Candida Or Torulopsis Patents (Class 435/255.4)
  • Patent number: 6489147
    Abstract: A gene which contains the nucleotide sequence shown in SEQ ID NO:1 from nucleotide 671 to nucleotide 6295 or a nucleotide sequence which can be obtained therefrom by substitution, insertion or deletion of up to 30%, preferably up to 10%, particularly preferably up to 20%, especially preferably up to 5%, of the nucleotides, and whose gene product has the enzymatic activity of an adenylate cyclase, and its use.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: December 3, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Regula Altmann-Jöhl, Peter Philippsen, Henning Althöfer, Harald Seulberger
  • Patent number: 6444204
    Abstract: The present invention relates to the field of bio-technologies and environmental protection, and refers the cleaning of water, soil and other media polluted with petroleum products. The cleaning method of the present invention is carried out with a biological preparation that comprises a pool of yeast of the Candida maltosa genus from the strains deposited under No. VKPM Y-2256 and No. VKPM Y-2257. These strains may be present in the pool in any ratio but preferably in the ratio of 1:1. The biological preparation may be used for removing pollution caused by a wide range of hydrocarbons contained in crude oil and petroleum products, for example fuel oil, oils, etc. The biological preparation affords recovery of oil pollution at temperatures up to +41° C. and pH 3.0-9.0, and may be used in saline ecosystems.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: September 3, 2002
    Inventors: Petr Alexandrovich Kuznetsov, Penker Babaevna Avchieva
  • Patent number: 6426204
    Abstract: A D-arabinitol dehydrogenase enzyme is disclosed. The enzyme is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol and is substantially free of other enzymes capable of oxidizing D-mannitol. Also disclosed are methods for determining D-arabinitol. In one embodiment the method comprises the steps of providing in combination (1) a medium suspected of containing D-arabinitol and (2) a D-arabinitol dehydrogenase enzyme and examining the medium for the product of the oxidation of the D-arabinitol. The enzyme utilized is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol. Kits for conducting the present method are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 30, 2002
    Assignee: Dade Behring Marburg GmbH
    Inventors: Charles Garrett Miyada, Arthur C. Switchenko, Melanie W Quong, Man-Ying Laurie Wong
  • Patent number: 6423310
    Abstract: Novel methods and compositions are provided for the biocontrol of plant diseases by use of a biological coating that confers both a protective and a curative effect for the control of postharvest decay. The coating includes chitosan salts, an antagonistic microorganism, and a cation. A composition of chitosan salts, CaCl2 and yeast is effective. The combined fungicidal activities of the chitosan salts and the antagonistic microorganism make the compositions of the present invention superior to previous coatings. When applied to the surface of a harvested plant commodity, the compositions both prevent and cure postharvest decay.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: July 23, 2002
    Assignees: Biotechnology Research and Development Corporation, The United States of America as represented by the Secretary of Agriculture
    Inventors: Charles Wilson, Ahmed El Ghaouth
  • Patent number: 6379678
    Abstract: The present invention relates to antigenic preparations comprising polysaccharides and/or glycopeptides preparable from keratinophilic fungi as well as yeasts, processes for the preparation of these antigenic preparations, their use as pharmaceutical substances as well as their use as vaccines, including but not limited to, the prophylaxis and treatment of allergy, as well as for modulating the immune response.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: April 30, 2002
    Assignee: Boehringer Indgelheim Vetmedica GmbH
    Inventors: Dieter Farnow, Joachim Karle, Igor D. Poliakov, Ludmilla G. Ivanova
  • Patent number: 6379937
    Abstract: The present invention relates to a novel process for the preparation of mixture of 19 hydroxyeicosatetraenoic acid and 20 hydroxyeicosatetraenoic acid (19 HETE and 20 HETE) by biotransformation of Arachidonic acid or Poly Unsaturated Fatty Acids (PUFA) with yeast as the biotransforming agent.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: April 30, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Asmita Ashutosh Prabhune, Colin Ratledge
  • Patent number: 6346411
    Abstract: An isolated and purified DNA molecule encoding Candida albicans protein with integrin-like motifs, the protein itself, antibodies thereto, and methods of use, are provided.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: February 12, 2002
    Assignee: Regents of the University of Minnesota
    Inventors: Margaret K. Hostetter, Cheryl A. Gale, Catherine M. Bendel, Nian-jun Tao
  • Patent number: 6344231
    Abstract: A composition of yeast extract from genus Candida is provided. In the said composition, contents of mannitol, glutamic acid, alanine, 5′-IMP and 5′-GMP are above 0.5%, above 2.0%, above 0.5%, above 1.5% and above 1.5%, respectively, all of which should simultaneously be satisfied the condition. Increased contents of alanine and 5′-IG of the extract of Candida yeast resulted to obtain yeast extract having sea tangle (kombu) (Laminariales, kelps)-like taste and flavor.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: February 5, 2002
    Assignee: Nihon Tobacco Inc.
    Inventors: Yukihiro Nakajo, Hiroyuki Sano
  • Publication number: 20010055796
    Abstract: A fermentation process for preparing a high yield erythritol using a salt tolerant mutant of Candida sp. [Candida magnoliae SR101:KCCM-10160]. More specifically, the present invention relates to a process for preparing erythritol under optimal fermentation conditions for maximal erythritol production by optimizing the environmental conditions of culture, including medium component, pH, temperature, aeration rate and agitation speed.
    Type: Application
    Filed: August 17, 2001
    Publication date: December 27, 2001
    Applicant: Bolak Co. Ltd.
    Inventors: Jin Ho Seo, Yeon Woo Ryu, Soo Ryun Jung, Sang Yong Kim
  • Patent number: 6287833
    Abstract: A D-arabinitol dehydrogenase enzyme is disclosed. The enzyme is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol and is substantially free of other enzymes capable of oxidizing D-mannitol. Also disclosed are methods for determining D-arabinitol. In one embodiment the method comprises the steps of providing in combination (1) a medium suspected of containing D-arabinitol and (2) a D-arabinitol dehydrogenase enzyme and examining the medium for the product of the oxidation of the D-arabinitol. The enzyme utilized is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol. Kits for conducting the present method are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 11, 2001
    Assignee: Dade Behring Marburg GmbH
    Inventors: Charles Garrett Miyada, Arthur C. Switchenko, Melanie W. Quong, Man-Ying Laurie Wong
  • Patent number: 6284480
    Abstract: The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: September 4, 2001
    Assignee: Cytokinetics, Inc.
    Inventors: Corey E. Nislow, Roman Sakowicz, Christophe Beraud
  • Patent number: 6280988
    Abstract: A D-arabinitol dehydrogenase enzyme is disclosed. The enzyme is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol and is substantially free of other enzymes capable of oxidizing D-mannitol. Also disclosed are methods for determining D-arabinitol. In one embodiment the method comprises the steps of providing in combination (1) a medium suspected of containing D-arabinitol and (2) a D-arabinitol dehydrogenase enzyme and examining the medium for the product of the oxidation of the D-arabinitol. The enzyme utilized is capable of catalyzing the oxidation of D-arabinitol and substantially incapable of catalyzing the oxidation of D-mannitol. Kits for conducting the present method are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 28, 2001
    Assignee: Dade Behring Marburg GmbH
    Inventors: Charles Garrett Miyada, Arthur C. Switchenko, Melanie W Quong, Man-Ying Laurie Wong
  • Patent number: 6271007
    Abstract: The invention relates to novel yeast strains having a reduced ability to metabolize xylitol. The invention further relates to the use of said strains for the production of xylitol.
    Type: Grant
    Filed: February 7, 1994
    Date of Patent: August 7, 2001
    Assignee: Xyrofin Oy
    Inventors: Juha Apajalahti, Matti Leisola
  • Patent number: 6224915
    Abstract: The aim of the present invention is to obtain bioproteins derived from whey and/or wheyey residues and waste of the dairy industry. The obtainment of these bioproteins therefore entails the treatment of the whey and/or wheyey residues and includes a method for eliminating the lactose contained in milk in order to subsequently be able to extrapolate the proteins therefrom so that they constitute a product which is reusable and, in particular, generally digestible. In order to provide the treatment according to the invention, there are also particular plant stages for performing this elimination at the cellular level. It is particularly important for the invention that specific microorganisms are used which perform the elimination at the cellular level of the lactose contained in whey and/or wheyey residues.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: May 1, 2001
    Inventor: Riccardo Reverso
  • Patent number: 6171828
    Abstract: The present invention discloses a method for culturing microorganisms having a methanol metabolic pathway in which an expression unit is introduced that comprises a target gene linked downstream from a promoter that can be induced by methanol; wherein, during the culturing period, and including the period during which methanol is continuously or periodically added, the rate of addition is adjusted to a rate equal to or less than the maximum methanol consumption rate of said microorganisms.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: January 9, 2001
    Assignee: Suntory Limited
    Inventors: Koji Magota, Tomohiro Rogi, Yasuyoshi Sakai, Nobuo Kato