Cylindrical Reaction Tank Or Vessel Horizontally Disposed With Respect To Its Central Axis Patents (Class 435/298.1)
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Patent number: 8969073Abstract: The invention describes an appliance and a method, with the help of which specific bio-particles, but also dissolved bio-molecules can be recognized in and separated from fluids making use of suitable carriers and known immobilization methods. The appliance can be used both discontinuously and also for direct and continuous treatment of fluids. Fields of application of the invention are animals, bio-technology (including biological research) and medicinal diagnostics. Areas of application of the invention comprise, among others, therapy of humans, in particular direct treatment of blood.Type: GrantFiled: January 30, 2007Date of Patent: March 3, 2015Assignee: pluriSelect GmbHInventor: Hans Werner Heinrich
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Patent number: 8962310Abstract: The subject invention provides advantageous systems and processes for anaerobic digestion of organic waste streams, particularly agricultural waste streams. According to this invention, a new process is provided in which a liquid fraction from an organic waste stream comprising soluble compounds is segregated and incubated in a reactor separate from the solids fraction of the organic waste stream. Digestion of waste in both reactors occurs substantially simultaneously and both reactors produce biogas (thus both reactors function essentially like single stage reactors but allow for continuous or intermittent loading). According to one aspect of the invention, at least one cross-flow baffle is provided for use in an anaerobic digester to collect biogas and break up clumped solids in the reactor. In another aspect of the invention, packing media for use in an anaerobic digester is provided.Type: GrantFiled: March 14, 2013Date of Patent: February 24, 2015Assignee: University of Florida Reearch Foundation, Inc.Inventors: Pratap Pullammanappallil, Kerry Johanson, Ioannis Martinos Polematidis, John M. Owens, David P. Chynoweth
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Publication number: 20140242689Abstract: The invention relates biotechnology. The vortex bioreactor comprises a cylindrical tank with a lid, a device for agitating a medium, said device being located in the tank and consisting of a bladed wheel secured horizontally on a vertical shaft in the upper portion of the tank and a horizontal annular baffle mounted in the tank with a gap relative to the cylindrical walls of the tank and having a central axial orifice. The horizontal annular baffle is situated on a vertical rod that is capable of rotating. A mechanism for adjusting the position of the horizontal annular baffle on the rod is disposed on the vertical rod. A tube or telescopic tube is disposed inside the cylindrical tank and is joined to the axial orifice of the horizontal annular baffle. Said tube is affixed to the baffle from below and is disposed around the rod.Type: ApplicationFiled: August 15, 2011Publication date: August 28, 2014Applicant: OBSCHESTVO S OGRANICHENNOI OTVETSVENNOSTJU "TSENTR VIKHREVYKH TEKHNOLOGYInventors: Yury Akhmetovich Ramazanov, Andrei Petrovich Repkov
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Patent number: 8809043Abstract: A system and method for rotating a cell growth chamber of a cell expansion system includes a rotatable member for engaging a chamber coupling attached to the cell growth chamber. The rotatable member includes an independently operable mechanism for engaging a rotatable fitting associated with the chamber coupling. In at least one embodiment, the chamber coupling is selectively rotatable by turning the rotatable member, thereby rotating the cell growth chamber around a first axis. The cell growth chamber is also selectively rotatable around a second axis by turning the rotatable fitting associated with the chamber coupling. Other novel aspects include a way of attaching the cell growth chamber to the shaft assembly, and a new tube routing clip.Type: GrantFiled: February 13, 2013Date of Patent: August 19, 2014Assignee: Terumo BCT, Inc.Inventors: Paul M. Leuthaeuser, Jon A. Dodd, Thomas G. Dilorenzo
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Patent number: 8728802Abstract: An improved apparatus and process for treating biomass bearing material including municipal solid waste (MSW). The apparatus includes a reaction vessel configured for rotation and steam injection, with helically arranged auger vanes attached to the internal walls of the vessel, a self aligning door. Embodiments includes various of a heated jacket, modified raised projections on the top edge of the auger vanes, a modified door, modified door sealing assembly, and a process of quick charging the interior of the vessel with steam.Type: GrantFiled: June 29, 2010Date of Patent: May 20, 2014Assignee: Biomass Worldwide Group LimitedInventor: Anthony P. Noll
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Patent number: 8716010Abstract: A photobioreactor system is provided that comprises a bioreactor including at least two bioreactor tubes, each having an end and a hollow interior, the ends being connectively joined by one or more connector units having a hollow portion defined by a circumference, a solar concentrator configured to collect and concentrate solar power, at least one light guide associated with the solar concentrator to illuminate the hollow portion of the one or more connector units, and at least one LED illuminating the one or more connector units.Type: GrantFiled: December 15, 2010Date of Patent: May 6, 2014Assignee: GE Lighting Solutions, LLCInventors: István Csányi, Laszlo Balazs, Janos Sneider, Erazmus Gerencser
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Patent number: 8709796Abstract: The invention concerns a device for preparing a body fluid for a bacteriological analysis thereof comprising a container provided with a chamber (4) wherein a piston (5) is mobile between an opening position and a closing position, the chamber (4) including a separation zone (7) and means for introducing (15, 16) a fluid into said chamber and the piston (5) including a closure means (8) co-operating with the separation zone (7) so as to define an upper volume (9) and a lower volume (10) on either side of said zone, the upper volume (9) and the lower volume (10) mutually communicating when the piston (5) is in opening position and being tightly isolated from each other when the piston (5) is in closing position. The invention also concerns a preparation method using such a device (1).Type: GrantFiled: July 11, 2006Date of Patent: April 29, 2014Assignee: Becton, Dickinson and CompanyInventors: Isabelle Besson Faure, Jean-Pierre Hermet, Sébastien Ribault
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Publication number: 20130267020Abstract: Provided herein are a culture apparatus, culture systems and an alternating ionic magnetic resonance electromagnetic chamber for culturing cells, tissues or organoid bodies or for delivering a pulsating alternating ionic magnetic resonance field to an object of interest including the above or to an animal, human or plant. The culture apparatus comprises a culture unit having growth and nutrient modules and a randomizing adapter to continually randomize the gravity vector in the growth module. The culture systems further comprise the alternating ionic magnetic resonance electromagnetic chamber.Type: ApplicationFiled: April 9, 2013Publication date: October 10, 2013Inventors: Thomas J. Goodwin, Moses J. Kushman
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Patent number: 8546142Abstract: The invention is a reverse-flow method and system for the loading, proliferation and differentiation of cells into and throughout an implantable biocompatible three-dimensional scaffold.Type: GrantFiled: March 4, 2005Date of Patent: October 1, 2013Assignee: Millenium Biologix Technologies Inc.Inventors: Ivan Martin, David Wendt, Alessandra Braccini, Rodolfo Quatro, Marcel Jakob
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Patent number: 8507266Abstract: A bioreactor system includes a housing and a hydrostatic loading module. The housing includes a chamber with an inlet port and an outlet port. The inlet and outlet ports allowing the chamber to be continuously perfused with a culture medium while chamber is hydrostatically loaded.Type: GrantFiled: November 4, 2004Date of Patent: August 13, 2013Assignee: Case Western Reserve UniversityInventors: Jean F. Welter, Luis A. Solchaga, Jim A. Berilla, Kitsie Penick
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Patent number: 8496837Abstract: A process for affecting reductive conversion reactions in a reactor using the palladized bacterial cellulose immobilized on a support for reductive conversion reactions in a reactor.Type: GrantFiled: April 2, 2008Date of Patent: July 30, 2013Assignees: Department of Biotechnology, Indian Institute of TechnologyInventors: Upendra Patel, Sumathi Suresh
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Patent number: 8431391Abstract: A plant for producing an oxygen-containing additive for liquid motor fuels comprises an anaerobic fermentation vessel, a gasholder, a system for removal of sulphuretted hydrogen, and a hotwell. The plant further comprises an aerobic fermentation vessel, a device for liquid substance pumping, a device for liquid aeration with an oxygen-containing gas, a removal system of solid mass residue after fermentation, a gas distribution device; a device for heavy gases utilization; a device for ammonia adsorption by water; a liquid-gas mixer; a cavity mixer, a system that serves superficial active and dispersant matters and a cooler; all of these being connected to each other by pipelines. The technical result being the implementation of a process for producing an oxygen containing additive, which after being added to liquid motor fuels, provides an ecologically beneficial component for motor fuels by ensuring the stability of composition fuel properties during long-term storage.Type: GrantFiled: October 26, 2009Date of Patent: April 30, 2013Assignee: U.S. Department of EnergyInventors: Yury Paul Siryk, Ivan Peter Balytski, Volodymyr George Korolyov, Olexiy Nick Klishyn, Vitaly Nick Lnianiy, Yury Alex Lyakh, Victor Valery Rogulin
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Patent number: 8399245Abstract: A system and method for rotating a cell growth chamber of a cell expansion system includes a rotatable member for engaging a chamber coupling attached to the cell growth chamber. The rotatable member includes an independently operable mechanism for engaging a rotatable fitting associated with the chamber coupling. In at least one embodiment, the chamber coupling is selectively rotatable by turning the rotatable member, thereby rotating the cell growth chamber around a first axis. The cell growth chamber is also selectively rotatable around a second axis by turning the rotatable fitting associated with the chamber coupling. Other novel aspects include a way of attaching the cell growth chamber to the shaft assembly, and a new tube routing clip.Type: GrantFiled: February 9, 2010Date of Patent: March 19, 2013Assignee: Terumo BCT, Inc.Inventors: Paul M. Leuthaeuser, Jon A. Dodd, Thomas G. DiLorenzo
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Patent number: 8389064Abstract: A system and method are provided for protecting bio-reactor housing from solar radiation, by applying UV-protective material to an outer surface of a plastic wall of the bio-reactor housing to protect from solar radiation. The housing includes a wall formed of plastic that defines the outer surface. In this manner, the effective life of the housing is extended and the overall cost of generation of photosynthetic biomass is decreased, improving system performance and cost-effectiveness.Type: GrantFiled: October 18, 2008Date of Patent: March 5, 2013Assignee: Combined Power, LLCInventor: John D. H. King
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Patent number: 8247223Abstract: The methods are disclosed to introduce catalysts and fluids into an apparatus and/or media to effect remediation of contaminants, improve soil fertility and permeability, control undesirable pests, or create useful chemicals or food. Aerobic metabolism of compounds in a media is facilitated through the transfer of fluids, such as air. The apparatus and methods provide an environment for select organisms, including refugia and nutrient substrate. The biodegradable composition of the apparatus is partially transformed by catalytic treatment. Catalysts or remediation agents are produced in-situ, for specific applications that provide a range of retention, activation, activity, and release profiles.Type: GrantFiled: February 13, 2012Date of Patent: August 21, 2012Inventors: Robert William Rawson, Mia Rose Maltz
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Patent number: 8191202Abstract: The apparatus comprises a vacuum tank with a front-mounted collection means thereunder The collection means is a V-shaped scraper with a height adjustable suction inlet at the apex thereof. The collection means has a pair of laterally adjustable pivoting wings for varying its width to correspond to that of an alley or gutter. The suction inlet may be equipped with a snorkel to introduce a small quantity of air as an aid in entraining thick-consistency materials. A blower vac is used to both draw air into and blow air through the vacuum tank. A valve means comprising a pair of oppositely oriented check valves is used to alternate flow paths between a lowered rearward exhaust during collection and an elevated intake during tank discharge.Type: GrantFiled: August 4, 2010Date of Patent: June 5, 2012Assignee: Nuhn Industries Ltd.Inventor: Dennis Nuhn
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Publication number: 20120129257Abstract: The invention relates to an apparatus (1) for culturing anchorage-dependent cells. The apparatus (1) comprises a housing (2) with an inlet (4) and an outlet (5), and a plurality of culture plates (6) removably stacked within the housing (2). The housing (2) has a circumferential wall (7), a base (8) and a top wall (9). The base (8) comprises the inlet (4) and the top wall (9) comprises the outlet (5). The circumferential wall (7) of the housing (2) defines a longitudinal axis thereof, as well as an inner cross section perpendicular to the longitudinal axis. Shape and dimensions of the inner cross section are essentially uniform along the longitudinal axis. The culture plates (6) are arranged at least essentially parallel to each other. Each plate (6) is mounted and sealed to the circumferential wall (7) of the housing (2). Plates (6) are arranged at a distance from each other. Each culture plate (6) has a through hole (14), so that inlet (4) and outlet (5) are in fluid communication.Type: ApplicationFiled: October 8, 2009Publication date: May 24, 2012Applicant: Agency for Science, Technology and ResearchInventors: Hanry Yu, Lei Xia, Hwa Liang Leo
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Patent number: 8114664Abstract: A flexible wall bioreactor is described that uses a small droplet size mist unit, a lower rate ambient air flow rate, and a flexible wall culture chamber to provide an environment that allows for the growth of dense root matrix, shoot cultures, and 2 and 3 dimensional animal tissues.Type: GrantFiled: July 14, 2008Date of Patent: February 14, 2012Assignee: Worcester Polytechnic InstituteInventors: Pamela J. Weathers, Melissa J. Towler
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Patent number: 8114659Abstract: This apparatus introduces catalysts and fluids into a media to effect remediation of contaminants, improve soil fertility and permeability, control undesirable pests, or create useful chemicals or food. The apparatus generates and releases enzymes, metabolites, and biologically active organisms. Aerobic metabolism of compounds in a media is facilitated through the transfer of fluids, such as air. The apparatus and methods provide an environment for select organisms, including refugia and nutrient substrate. The biodegradable composition of the apparatus is partially transformed by catalytic treatment. Catalysts or remediation agents are produced in-situ, for specific applications that provide a range of retention, activation, activity, and release profiles. The apparatus is placed in contact with media. Catalytic infusion of media by biological consortia, such as fungi, releases exudates that transform or biodegrade materials.Type: GrantFiled: January 14, 2009Date of Patent: February 14, 2012Inventors: Robert William Rawson, Mia Rose Maltz
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Patent number: 8101217Abstract: A method includes operating an apparatus having a mash circulating and recirculating system with pump and fermentation tank, an atmosphere circulating and recirculating system with blower for recirculating atmosphere between the tank and an ethanol-removal station, and an integrated refrigerating heat-transfer system with first coils remote from the tank for condensing out ethanol from the atmosphere, and second coils for warming the mash. The entire apparatus can be up-sized or down-sized for specific applications. In one form, the system includes electrically-driven pump, blower, and refrigeration compressors, with the external energy consumption being entirely electrical and kept surprisingly low.Type: GrantFiled: May 31, 2011Date of Patent: January 24, 2012Assignee: ENE003, LLCInventors: Scott Sovereign, Frank A. VanKempen
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Publication number: 20110287529Abstract: Disclosed are a syringe-shaped culture tube which has a wide surface area and is changeable by a user to a desired size, and a cell culture apparatus in which a plurality of the culture tubes are mounted. The cell culture apparatus allows a culture medium to constantly and smoothly contact the entire inner circumference of the culture tube and rotate by a rotation unit at a preset speed when the culture tube is filled with the culture medium. Thus, the cell culture apparatus can promote stirring and gas supply and increase the gas exchange rate. Also, it can reduce consumption of the culture medium.Type: ApplicationFiled: September 23, 2009Publication date: November 24, 2011Applicant: CoreStem Co., Ltd.Inventors: Seok Kee Hong, Si Eun Yang, Kyung Suk Kim, Hyun Soo Yoon, Tae Yong Lee, Jin Hwa Lee
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Publication number: 20110236932Abstract: The present invention relates to a series of therapeutic material processing devices stacked into a column, hereby creating a bio material process plant with extremely small foot-print and all the processing devices being of single-use capabilities for lowest possible cost and methods of operating said column.Type: ApplicationFiled: December 18, 2009Publication date: September 29, 2011Applicant: STOBBE TECH A/SInventor: Per Stobbe
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Patent number: 8026095Abstract: Apparatus for biological production of ethanol from waste gases includes a bioreactor including a plurality of tunnels each having inlet and outlet passageways, a gasifier reactor generates a continuous supply of syngas from waste gases into the upper portion of each tunnel. A mixing device provides a continuous supply of fermentation microbes in a liquid directed by pumps and spray misters into the tunnel. Pumps direct the liquid vertically for conversion of the syngas into ethanol.Type: GrantFiled: June 2, 2007Date of Patent: September 27, 2011Inventor: Ingo Krieg
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Patent number: 8003379Abstract: A bioreactor and bioreactor system are suitable for the growth of materials from algae. More specifically, the system preferred embodiments use concentrated sunlight in a solo- or co-generation system to produce algae and products therefrom as well as solar thermal energy.Type: GrantFiled: August 1, 2007Date of Patent: August 23, 2011Assignee: Brightsource Energy, Inc.Inventors: Arnold J. Goldman, Michael Kagan, Yuri Kokotov
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Patent number: 7972825Abstract: An apparatus includes a mash circulating system with pump and fermentation tank, an atmosphere circulating system with blower for circulating atmosphere between the tank and an ethanol-removal station, and an integrated refrigerating heat-transfer system with first coils for condensing out ethanol from the atmosphere, and second coils for warming the mash. A support frame supports portions of the above components, making it a transportable modular unit to facilitate installation, minimize cost, and provide for efficient operation. The entire apparatus can be up-sized or down-sized for specific applications. In one form, the system includes electrically-driven pump, blower, and refrigeration compressors, with the external energy consumption kept surprisingly low. Methods related to the above are also disclosed.Type: GrantFiled: February 13, 2009Date of Patent: July 5, 2011Assignee: ENE003, LLCInventors: Scott Sovereign, Frank A. VanKempen
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Patent number: 7960172Abstract: A method and an apparatus are provided for aeration of organic material, wherein the organic material undergoes an aerobic composing process, such that air is caused to evenly penetrate the organic material. The organic material is first sealed in a vessel. Air is then delivered to the contents of the vessel such that an air pressure of from about 1 to about 1000 kPa above atmospheric pressure is maintained in the vessel. A pressure differential initially forms and is then allowed to equilibrate over a period of time, in which time air flows from areas of high pressure to areas of low pressure in the organic material thus ensuring that aeration is evenly distributed throughout the organic material.Type: GrantFiled: September 23, 2008Date of Patent: June 14, 2011Assignee: AnaeCo LimitedInventor: Thomasz Rudas
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Patent number: 7919304Abstract: A process and system are disclosed for the biofiltration of volatile organic compounds. The process involved recirculating contaminated effluent gas through a biofilter (1), the biofilter (1) having an inlet (20), outlet (15) and micro-organism laden filter media bed (3). The filter media bed additionally having moisture retaining properties. This process has been effective in removing high levels of VOCs from effluent gas streams and also in removing VOCs from an effluent gas stream where the VOC levels and/or volumes of effluent gas vary over time.Type: GrantFiled: May 3, 2001Date of Patent: April 5, 2011Assignee: Bord Na MonaInventors: Imelda Egan, Ian Phillips
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Publication number: 20110070636Abstract: The present invention relates to a resilient member (FIG. 7b) and combination of resilient members into resilient devices. Particular embodiments of the present invention relate to a bio film reactor comprising a stack of bio film discs formed as a resilient member thereby allowing the stack of bio film discs to be self compensative at least partially for expansion of the stack as a result of e.g. changes in temperature. Furthermore, the resilient member and device according to the present invention provide a great flexibility as to the actual choice of material for the member and device. The male protrusions (4) of one resilient member (1) are introduced into the voids (5) of the female protrusions (3) of a similar or identical member (1). Male protrusions (4) of a second kind do not abut the bottom of the voids (5).Type: ApplicationFiled: May 18, 2009Publication date: March 24, 2011Applicant: GRUNDFOS BIOBOOSTER A/SInventor: Anders Dalsgaard
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Patent number: 7888111Abstract: An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting transport of nutrients and excretion of effete matter, and elevating the culturing efficiency improving effect by the structural features. In order to attain the above object, there is provided a cell culture vessel including a culture section provided with a plurality of projections having an equivalent diameter smaller than the cells to be cultured and the culture section side walls enclosing the culture section, wherein the distance between an arbitrary position on the culture section/side wall boundary line and the nearest projection is smaller than the diameter of the cells to be cultured. The effect of the projections in the vessel given to the cultured cells is enhanced.Type: GrantFiled: November 9, 2009Date of Patent: February 15, 2011Assignee: Hitachi, Ltd.Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Norihito Kuno
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Publication number: 20100233788Abstract: This apparatus and methods introduce catalysts and fluids into a media to effect remediation of contaminants, improve soil fertility and permeability, control undesirable pests, or create useful chemicals or food. The apparatus generates and releases enzymes, metabolites, and biologically active organisms. Aerobic metabolism of compounds in a media is facilitated through the transfer of fluids, such as air. The apparatus and methods provide an environment for select organisms, including refugia and nutrient substrate. The biodegradable composition of the apparatus is partially transformed by catalytic treatment. Catalysts or remediation agents are produced in-situ, for specific applications that provide a range of retention, activation, activity, and release profiles. The apparatus is placed in contact with media. Catalytic infusion of media by biological consortia, such as fungi, releases exudates that transform or biodegrade materials.Type: ApplicationFiled: January 14, 2009Publication date: September 16, 2010Inventors: Robert William Rawson, Mia Rose Maltz
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Patent number: 7790437Abstract: An organ transportation device includes a fluid-tight organ container and structure within the organ container for engaging an organ within the organ container. A base assembly is provided, and structure for rotating the organ engaging structure and the organ relative to the base assembly. The base assembly can have a motor and a battery to provide for rotation of the organ container during shipping.Type: GrantFiled: December 14, 2006Date of Patent: September 7, 2010Assignees: Biorep Technologies, Inc., The University of MiamiInventors: Ramon E. Poo, Camillo Ricordi
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Patent number: 7745208Abstract: The invention is an apparatus and a process for treating biomass bearing material including municipal solid waste (MSW). The apparatus includes a reaction vessel held at an angle and configured for rotation and steam injection, with helically arranged internal flights, a self-aligning door closure, and a swing-away door assembly. It also includes a novel structure for shredding biomass bearing material attached to the edges of the flights. This structure is a number of projecting tooth like points and paddles.Type: GrantFiled: February 15, 2006Date of Patent: June 29, 2010Inventor: Anthony P. Noll
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Patent number: 7709113Abstract: Systems and processes for producing hydrogen using bacteria are described. One detailed process for producing hydrogen uses a system for producing hydrogen as described herein, the system including a reactor. Anodophilic bacteria are disposed within the interior of the reactor and an organic material oxidizable by an oxidizing activity of the anodophilic bacteria is introduced and incubated under oxidizing reactions conditions such that electrons are produced and transferred to the anode. A power source is activated to increase a potential between the anode and the cathode, such that electrons and protons combine to produce hydrogen gas. In one system for producing hydrogen is provided which includes a reaction chamber having a wall defining an interior of the reactor and an exterior of the reaction chamber.Type: GrantFiled: January 27, 2009Date of Patent: May 4, 2010Assignees: The Penn State Research Foundation, Ion Power, Inc.Inventors: Bruce Logan, Stephen Grot, Thomas E. Mallouk, Hong Liu
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Patent number: 7691625Abstract: An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting transport of nutrients and excretion of effete matter, and elevating the culturing efficiency improving effect by the structural features. In order to attain the above object, there is provided a cell culture vessel including a culture section provided with a plurality of projections having an equivalent diameter smaller than the cells to be cultured and the culture section side walls enclosing the culture section, wherein the distance between an arbitrary position on the culture section/side wall boundary line and the nearest projection is smaller than the diameter of the cells to be cultured. The effect of the projections in the vessel given to the cultured cells is enhanced.Type: GrantFiled: May 26, 2006Date of Patent: April 6, 2010Assignee: Hitachi, Ltd.Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Norihito Kuno
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Patent number: 7682821Abstract: The invention provides a device for growing genetically enhanced aquatic photoautotrophic organisms in a stable culture, causing said organisms to produce ethanol, and then separating, collecting, and removing the ethanol in situ.Type: GrantFiled: October 30, 2007Date of Patent: March 23, 2010Assignee: Algenol Biofuels Switzerland GmbHInventors: R. Paul Woods, Edward Legere, Benjamin Moll, Carlos Unamunzaga, Eulalia Mantecon
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Patent number: 7651852Abstract: A method and an apparatus is provided for aeration of organic material, wherein the organic material undergoes an aerobic composting process, such that air is caused to evenly penetrate the organic material. The organic material is first sealed in a vessel. Air is then delivered to the contents of the vessel such that an air pressure of from about 1 to about 1000 kPa above atmospheric pressure is maintained in the vessel. A pressure differential initially forms and is then allowed to equilibrate over a period of time, in which time air flows from areas of high pressure to areas of low pressure in the organic material thus ensuring that aeration is evenly distributed throughout the organic material.Type: GrantFiled: October 26, 2001Date of Patent: January 26, 2010Assignee: AnaeCo LimitedInventor: Tomasz Rudas
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Publication number: 20090272688Abstract: The invention relates to a bioreactor (1) for the purification of waters, said reactor comprising a cross-sectionally essentially circular or elliptical tank section (2) provided with inlet means (5) for water to be purified and outlet means (6) for purified water. The tank holds thereinside carrier material (3) on which a biofilm may develop. The tank is further provided with means (4) for supplying a fluid which contains a reaction gas required by the purification process, such that the water to be purified develops gas bubbles containing a reaction gas. The tank section is adapted to be essentially full of water during the purification process. The fluid supply means (4) are disposed on the tank wall and the reactor comprises control means for operating the fluid supply means in such a way that a spinning motion of the carrier, the water, and at least some of said reaction-gas bearing bubbles is effected thereby around a rotation centerline passing essentially through the tank's cross-sectional center.Type: ApplicationFiled: December 22, 2006Publication date: November 5, 2009Inventor: Gennadi Zaitsev
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Patent number: 7604987Abstract: The invention relates to a bioreactor comprising a chamber for containing cells or tissue cultures within a culture medium. The bioreactor also comprises a detector capable of detecting a change in one or more metabolites associated with growth of the cell or tissue cultures within the chamber and a chamber drive capable of rotating the chamber at a first speed about a first axis and a second speed about a second axis, the second axis being disposed at an angle relative to the first axis. In use, the magnitude of the first speed and the second speed are independently variable of each other.Type: GrantFiled: May 6, 2005Date of Patent: October 20, 2009Assignee: National University of SingaporeInventors: Dietmar W. Hutmacher, Swee Hin Teoh, Manoja Ranawake, Woon Shin Chong, Keng Soon Ting, Kay Chiang Chua, Than Myint, Chum Mok Puah, Toon Tien Foo, Jan-Thorsten Schantz
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Patent number: 7592173Abstract: Biofilm on glass beads deposited within a bottom portion of a vertically elongated bioreactor housing for possible experimental evaluation through a testing port in the housing which is also provided with inlet ports for aeration and infeed of nutrients with liquid. The biofilm collected within the housing chamber undergoes growth on glass slides within a cross-sectionally rectangular portion of the bioreactor housing from which the slides may be upwardly withdrawn under selective control without biofilm damage. The bioreactor housing arrangement also provides a high length to width ratio designed to enhance aeration.Type: GrantFiled: April 16, 2004Date of Patent: September 22, 2009Assignee: The United States of America as represented by the Secretary of the NavyInventors: David M. Stamper, Marianne Walch, Darrell H. Hill
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Publication number: 20090203119Abstract: A reactor for the conversion of biomass material includes an elongate annular chamber with an inner wall and an outer casing. A screw conveyor extends from one end into the chamber to feed biomass material. A heat source is provided within the inner wall of the chamber, and may be comprised of a series of permanent magnet assemblies mounted for rotation within a sleeve of electrically conductive material. The sleeve also serves as the inner wall of the chamber. Each magnet assembly includes a series of magnets spaced apart on a periphery of a circular support. A layer of insulating material is provided between the magnet assemblies and the sleeve. A rotatable shaft adapted for connection to a driving power source provides a mounting for the magnet assemblies.Type: ApplicationFiled: July 25, 2007Publication date: August 13, 2009Inventor: Brian Anthony Evans
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Patent number: 7563371Abstract: A tubular plug flow digester system assembled from manufactured components, including a holding/heating tank (15) connected to a manifold (14) that feeds a single or multiple parallel injection pumps (12). These pumps force feedstock though check valves (13) and into single or parallel digester hulls. This hulls are composed of manufactured parts including tapered end sections (11) and hull sections (10) that can be assembled onsite to a configuration that accommodates operational needs. Biogas produced by this digester is pressurized due to a liquid column created by an elevated effluent outlet (25). Feedstock is inoculated with relevant microorganisms that promote the generation of methane-rich biogas. Inoculation members (26) positioned within the hulls shelter biofilms containing these microbes while allowing regions of the biofilm to slough or naturally release microbes into the flowing feedstock stream. Biogas is collected through a manifold (22) and its release is controlled by a regulator or a valve.Type: GrantFiled: April 13, 2006Date of Patent: July 21, 2009Inventors: William Jason McCune-Sanders, Theodore Guy Roberts
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Patent number: 7510866Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).Type: GrantFiled: October 29, 2003Date of Patent: March 31, 2009Assignee: Korea Institute of Science and TechnologyInventors: Kuiwon Choi, Tae Soo Bae, Jung Kyu Kim, Chang Yang Lee
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Patent number: 7507577Abstract: The invention discloses a treatment apparatus for the excrement and a bio-toilet using the treatment apparatus. The treatment apparatus includes a tank, a reactor basin in the tank for containing the raw material and the excrement and having at least two parallel, concave parts having curved profile in the bottom part of the tank, a temperature control means for maintaining the temperature of the basin at a predetermined range; and at least two mixing devices which match with the at least two concave parts, each of them can rotate around a rotation shaft, the helical blade stirrer secured to the rotation shaft by a plurality of spokes. The bio-toilet is waterless, and thus a large quantity of water can be saved and the pollution of the environment due to the drainage of sewage can be avoided. Furthermore, treated by the treatment apparatus of the present invention, the microorganisms and the organic materials are combined and converted into stable loosen soil and the organic components.Type: GrantFiled: January 13, 2004Date of Patent: March 24, 2009Inventor: Andy Ming Fen Tung
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Patent number: 7491453Abstract: Systems and processes for producing hydrogen using bacteria are described. One detailed process for producing hydrogen uses a system for producing hydrogen as described herein, the system including a reactor. Anodophilic bacteria are disposed within the interior of the reactor and an organic material oxidizable by an oxidizing activity of the anodophilic bacteria is introduced and incubated under oxidizing reactions conditions such that electrons are produced and transferred to the anode. A power source is activated to increase a potential between the anode and the cathode, such that electrons and protons combine to produce hydrogen gas. One system for producing hydrogen includes a reaction chamber having a wall defining an interior of the reactor and an exterior of the reaction chamber. An anode is provided which is at least partially contained within the interior of the reaction chamber and a cathode is also provided which is at least partially contained within the interior of the reaction chamber.Type: GrantFiled: July 13, 2005Date of Patent: February 17, 2009Assignees: The Penn State Research Foundation, Ion Power, Inc.Inventors: Bruce Logan, Stephen Grot, Thomas E. Mallouk, Hong Liu
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Patent number: 7482154Abstract: The invention is an apparatus comprising a magnet adapted to create a diamagnetic force field at all points in space at which a magnetic field-field gradient product of the magnet has a value greater than or equal to a threshold value. At or above the threshold value, the diamagnetic force field induces a diamagnetic body force within a biological specimen supported within a bioreactor chamber that is disposed within the diamagnetic force field. The apparatus may alter the magnitude of the induced diamagnetic body force and may alter the direction of the induced diamagnetic body with respect to a spatial coordinate system or with respect to the direction of a secondary body force acting upon or within the biological specimen, thereby altering the vector sum of the induced diamagnetic body force and the secondary body force acting on the biological specimen.Type: GrantFiled: May 15, 2004Date of Patent: January 27, 2009Assignee: Rensselaer Polytechnic InstituteInventors: Natacha DePaola, Aleksandar G. Ostrogorsky
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Publication number: 20090017529Abstract: A flexible wall bioreactor is described that uses a small droplet size mist unit, a lower rate ambient air flow rate, and a flexible wall culture chamber to provide an environment that allows for the growth of dense root matrix, shoot cultures, and 2 and 3 dimensional animal tissues.Type: ApplicationFiled: July 14, 2008Publication date: January 15, 2009Applicant: WORCESTER POLYTECHNIC INSTITUTEInventors: Pamela J. Weathers, Melissa J. Towler
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Publication number: 20080299650Abstract: Apparatus for biological production of ethanol from waste gases includes a bioreactor including a plurality of tunnels each having inlet and outlet passageways, a gasifier reactor generates a continuous supply of syngas from waste gases into the upper portion of each tunnel. A mixing device provides a continuous supply of fermentation microbes in a liquid directed by pumps and spray misters into the tunnel. Pumps direct the liquid vertically for conversion of the syngas into ethanol.Type: ApplicationFiled: June 2, 2007Publication date: December 4, 2008Inventor: Ingo Krieg
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Patent number: 7449330Abstract: A bioreactor apparatus for processing waste, comprising a cylindrical pressure vessel having an inlet end and an exit end, an internally rotating main shaft having spaced apart ends, and a plurality of paddles and agitator bars attached to and extending radially from the shaft. At least some of the plurality of paddles and/or agitator bars extend radially outward from the shaft and form a helical spiral pattern when viewed from either of the spaced apart ends.Type: GrantFiled: August 30, 2002Date of Patent: November 11, 2008Assignee: Bouldin CorporationInventor: Floyd E. Bouldin
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Patent number: 7449331Abstract: The invention provides a roller bottle for cell growth culturing including a plurality of axial pleats therearound for increasing cell growth surface area and further including circumferential ribs integrally formed therewith for reinforcing the pleated wall structure. These circumferential ribs prevent the bottle walls from bowing outward when the inside of the bottle becomes pressurized during cell growth culturing.Type: GrantFiled: September 19, 2003Date of Patent: November 11, 2008Inventor: Kenneth W. Whitley
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Patent number: 7445927Abstract: A 10,000 gallon sequencing batch reactor tank for the on-site bio-degradation of oily sludge. Bacteria already present in and adapted to oily sludge degrade the hydrocarbons found in oily sludge within two weeks from 20,000 ppm to less than 100 ppm. A degradation cycle requires 5 days. After five days a recirculation pump and aeration system are turned off and solids are allowed to settle to the bottom of the tank. An ultrafiltration unit connected to the tank requires approximately 16 hours to process the contents of the reactor tank.Type: GrantFiled: September 3, 2004Date of Patent: November 4, 2008Assignee: The United States of America as represented by the Secretary of the NavyInventors: Gerardo F. Maga, Frederick E. Goetz