Abstract: This invention relates to the field of therapeutics. Disclosed are methods of conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand.

Abstract: The invention relates to a method for stimulating the growth of the plants and/or improving the biomass production and/or increasing the carbon fixation by the plant comprising introducing into a plant cell, plant tissue or plant one or more nucleic acids, wherein the introduction of the nucleic acid(s) results inside the chloroplast of a de novo expression of one or more polypeptides having the enzymatic activity of a glycolate dehydrogenase made up from translationally fused subunits of bacterial multi-subunit glycolate dehydrogenase enzymes.

Abstract: The present invention provides a method for cultivation of a genetically-modified plant that can highly produce a desired protein. More specifically, the present invention provides a method for cultivation of a genetically-modified plant comprising: cultivating the genetically-modified plant in a medium, wherein the genetically-modified plant is transformed by introducing an expression vector comprising a promoter regulating expression of RNA and a seed storage protein isolated from a plant that highly expresses RNA and the seed storage protein under a high nitrogen condition; and a polynucleotide encoding an objective protein, and wherein the medium is adjusted so that nitrate nitrogen is 70 mg/L to 750 mg/L and/or ammonium nitrogen is 70 mg/L to 750 mg/L for a definite period in a period from 30 days before an expected flowering date to a date on or before flowering of the genetically-modified plant.

Abstract: The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.

Abstract: Five novel plant transcription terminators MYB2, KTI1, PIP1, EF1A2, and MTH1 are isolated from soybean and their functions in the regulation of RNA transcription and processing in plants are described.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH364361. The invention thus relates to the plants, seeds and tissue cultures of the variety CH364361, and to methods for producing a corn plant produced by crossing a corn plant of variety CH364361 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH364361.

Abstract: The present invention provides methods of differentiating the infectivity and lethality of isolates of influenza virus and provides compounds for diagnosing, preventing, and treating outbreaks of influenza virus including compounds for diagnosing, preventing, and treating across different strains of influenza virus.

Abstract: The present invention provides a transgenic corn event MON87460, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for MON87460 in a sample, methods for detecting the presence of MON87460 event polynucleotides in a sample, and probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of MON87460 in a sample. The present invention also provides methods of breeding with MON87460 to produce water deficit tolerance corn plants.

Abstract: The present invention relates to the field of IgE-mediated allergy, particularly occupational asthma such as bakers asthma. More specifically the invention relates to the identification of a novel wheat allergen and the use thereof in therapy and diagnosis of IgE-mediated allergy. Furthermore the present invention provides the use of known peptides and proteins in therapy and diagnosis. The invention also relates to methods for diagnosis and treatment of IgE-mediated allergy in mammals.

Abstract: The invention relates to the isolation and characterization of a maize gene, RAMOSA3 (RA3), responsible for meristem development and inflorescence development including branching. The gene, gene product, and regulatory regions may be used to manipulate branching, meristem growth, inflorescence development and arrangement, and ultimately to improve yield of plants. The invention includes the gene and protein product as well as the use of the same for temporal and spatial expression in transgenic plants to alter plant morphology and affect yield in plants. The invention also includes the gene and protein product for SISTER OF RAMOSA3 (SRA).

Abstract: The present invention provides for peptides that bind to Receptor for Hyaluronic Acid Mediated Motility (RHAMM) molecules. More specifically, provided are peptides capable of specifically binding RHAMM molecules and capable of binding RHAMM with substantially high affinity. These novel RHAMM-binding peptides provide the basis for new imaging probes that can be used to identify cells expressing RHAMM, and for methods of imaging, prognosis, diagnosis and treatment of conditions associated with RHAMM expression.

Abstract: The invention provides an isolated polynucleotide comprising the sequence of SEQ ID NO: 1 or a variant thereof, wherein the variant encodes a polypeptide capable of modulating in a plant tolerance to at least one environmental stress selected from drought, cold, freezing, heat and salinity. The invention also provides construct, vectors, host cells, plant cells and plants genetically modified to comprise the polynucleotide. The invention also provides methods for producing and selecting plants that are tolerant to at least one environmental stress selected from drought, cold, freezing, heat and salinity, making use of the polynucleotides of the invention.

Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.

Abstract: The present invention relates to methods to modify at least one target locus in a plant cell, comprising, providing a plant cell with one or more target loci and one or more donor loci, followed by induction of homologous recombination between homologous regions of at least one target locus and at least one donor locus by at least one rare cleaving nuclease. The present invention related also to target loci, donor loci and nuclease loci used in these methods, and plant cells, plants and plant parts comprising these target loci, donor loci, nuclease loci and/or the recombined loci.

Abstract: A novel maize variety designated PH1TWW and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1TWW with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1TWW through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1TWW or a locus conversion of PH1TWW with another maize variety.

Abstract: Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased tolerance to abiotic stress (e.g., high or low temperature, drought, flood).

Abstract: Methods of simultaneously excising large nucleic acid sequences from a target nucleic acid and inserting large foreign nucleic sequences into the target nucleic acid sequence using DNA binding protein nucleases are described.

Abstract: A novel maize variety designated PH1MBR and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MBR with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1MBR through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1MBR or a locus conversion of PH1MBR with another maize variety.

Abstract: The invention relates to the soybean variety designated 01046169. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01046169. Also provided by the invention are tissue cultures of the soybean variety 01046169 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01046169 with itself or another soybean variety and plants produced by such methods.

Abstract: A novel maize variety designated PH1W03 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1W03 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1W03 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1W03 or a locus conversion of PH1W03 with another maize variety.

Abstract: Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH740515. The invention thus relates to the plants, seeds and tissue cultures of the variety CH740515, and to methods for producing a corn plant produced by crossing a corn plant of variety CH740515 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH740515.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH832984. The invention thus relates to the plants, seeds and tissue cultures of the variety CH832984, and to methods for producing a corn plant produced by crossing a corn plant of variety CH832984 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH832984.

Abstract: This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a Group H nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.

Abstract: The invention relates to the soybean variety designated 01045749. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01045749. Also provided by the invention are tissue cultures of the soybean variety 01045749 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01045749 with itself or another soybean variety and plants produced by such methods.

Abstract: The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3? termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait. One of ordinary skill in the art, having this data, can obtain cloned DNA fragments, synthetic DNA fragments or polypeptides constituting desired sequences by recombinant methodology known in the art or described herein.

Abstract: The invention relates to the soybean variety designated 01046192. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01046192. Also provided by the invention are tissue cultures of the soybean variety 01046192 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01046192 with itself or another soybean variety and plants produced by such methods.

Abstract: This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.

Abstract: The invention relates to the soybean variety designated A1036442. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1036442. Also provided by the invention are tissue cultures of the soybean variety A1036442 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1036442 with itself or another soybean variety and plants produced by such methods.

Abstract: The invention relates to the soybean variety designated 01046137. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01046137. Also provided by the invention are tissue cultures of the soybean variety 01046137 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01046137 with itself or another soybean variety and plants produced by such methods.

Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV931026. The invention thus relates to the plants, seeds and tissue cultures of the variety CV931026, and to methods for producing a corn plant produced by crossing a corn plant of variety CV931026 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV931026 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV931026.

Abstract: Nucleic acid molecules from cannabis has been isolated and characterized and encode polypeptides having aromatic prenyltransferase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.

Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.

Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.

Abstract: The present invention provides herein a polynucleotide sequence encoding the tubby-like protein, CaTLP1, from chickpea (Cicer arientium L.) that is responsive to abiotic stress and is involved in plant growth and development. Further, the recombinant DNA construct and recombinant vector comprising the polynucleotide sequence encoding CaTLP1, host cell comprising the recombinant vector and a process for producing a transgenic plant that expresses the CaTLP1 protein are also provided herein.

Abstract: As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion of exogenous sequences.

Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV062333. The invention thus relates to the plants, seeds and tissue cultures of the variety CV062333, and to methods for producing a corn plant produced by crossing a corn plant of variety CV062333 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV062333 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV062333.

Abstract: This invention discloses the development of a novel platform for recombinant production of bioactive glycoproteins and cancer specific vaccines in plants. Plants and plant cell cultures have been humanized with respect to human mucin-type protein O-glycosylation. A panel of plant cell factories for production of recombinant glycoproteins with designed human O-glycosylation, including an improved cancer vaccine candidate, has been developed. The platform provides basis for i) production of an essentially unlimited array of O-glycosylated human glycoprotein therapeutics, such as human interferon ?2B and podoplanin, and ii) for further engineering of additional cancer specific O-glycans on glycoproteins of therapeutical value. Currently, mammalian cells are required for human O-glycosylation, but plants offer a unique cell platform for engineering O-glycosylation since they do not perform human type O-glycosylation.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH250410. The invention thus relates to the plants, seeds and tissue cultures of the variety CH250410, and to methods for producing a corn plant produced by crossing a corn plant of variety CH250410 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH250410.

Abstract: A novel maize variety designated X13D063 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13D063 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13D063 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13D063, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13D063. This invention further relates to methods for producing maize varieties derived from maize variety X13D063.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH900059. The invention thus relates to the plants, seeds and tissue cultures of the variety CH900059, and to methods for producing a corn plant produced by crossing a corn plant of variety CH900059 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH900059.

Abstract: The present invention pertains to a novel and extensive analytical platform for selecting genes with a possible commercial phenotype from a large group of candidate genes identified using tools in bioinformatics, data from EST sequencing and DNA array. An aspect of the invention provides a method of producing a transgenic plant having an increased growth compared to its wild type. The method comprises altering in the plant the level of a gene product of at least one gene specifically expressed during different phases of wood formation. Further aspects of the invention provide a plant cell or plant progeny of a transgenic plant comprising a recombinant polynucleotide according to the invention. Other aspects pertain a DNA construct comprising a nucleotide sequence of the invention and a plant cell or plant progeny comprising the DNA construct.

Abstract: The invention provides seed and plants of tomato line CHI 12-94083. The invention thus relates to the plants, seeds and tissue cultures of tomato line CHI 12-94083, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.

Abstract: A novel maize variety designated PH1VVD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1VVD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1VVD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1VVD or a locus conversion of PH1VVD with another maize variety.

Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV684080. The invention thus relates to the plants, seeds and tissue cultures of the variety CV684080, and to methods for producing a corn plant produced by crossing a corn plant of variety CV684080 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV684080 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV684080.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH445169. The invention thus relates to the plants, seeds and tissue cultures of the variety CH445169, and to methods for producing a corn plant produced by crossing a corn plant of variety CH445169 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH445169.

Abstract: A soybean cultivar designated 34251723 is disclosed. The invention relates to the seeds of soybean cultivar 34251723, to the plants of soybean cultivar 34251723, to the plant parts of soybean cultivar 34251723, and to methods for producing progeny of soybean cultivar 34251723. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 34251723. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 34251723, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 34251723 with another soybean cultivar.

Abstract: This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity.

Abstract: The present invention is to provide a novel non-diffusing plant virus vector wherein virus vector infection and proliferation are possible only in a recombinant plant transformed with a gene necessary for viral proliferation, thereby enabling avoidance of unintended diffusion of a recombinant virus, a selective and specific expression system therefor, and a method of expression thereof which comprises combining a non-diffusing virus vector lacking a gene involved in intercellular movement of a cucumber mosaic virus (CMV) genome and a transgenic plant transformed with the lacked gene involved in intercellular movement for the non-diffusing virus vector to establish infection and proliferation selectively and specifically in the transgenic plant.