Indomethacine Per Se Or Ester Thereof Patents (Class 514/420)
  • Pharmaceutical preparations
    Patent number: 4545992
    Abstract: A pharmaceutical preparation for external use which comprises a solution of a non-steroid antipholgistic analgesic agent which is dissolved in at least one adjuvant selected from the group consisting of peppermint oil, methyl salicylate, ethyl salicylate and monoglycol salicylate in an amount at least sufficient to dissolve said antipholgistic analgesic agent, and bases for external use.
    Type: Grant
    Filed: July 26, 1982
    Date of Patent: October 8, 1985
    Assignee: Toko Yakuhin Industry Co., Ltd.
    Inventor: Takuzo Kamishita
  • Gel-like ointment containing indometacin
    Patent number: 4540572
    Abstract: In addition to indometacin, the gel-like ointment for the topical treatment of inflammation contains a water-soluble cellulose ether or/and a polyacrylic acid, the carboxyl groups of which are neutralized by a water-soluble amine, plus water and ethanol or isopropanol; the components are present in the ratio of amounts suitable for forming a gel. Determination of the level of indometacin in the serum of humans has shown that the absorption through the skin of the active compound from the new ointment is significantly higher than that from the most closely related products.
    Type: Grant
    Filed: December 29, 1983
    Date of Patent: September 10, 1985
    Assignee: Mepha AG
    Inventor: Pyare Seth
  • Antiinflammatory analgesic gelled ointment
    Patent number: 4525347
    Abstract: An antiinflammatory analgesic ointment comprising: (a) an antiinflammatory amount of indomethacin; (b) a medium consisting of a hydroxy compound in the range of from 15 to 85% by weight, water in the range of 30 to 55% by weight and a gelating agent being present in an amount sufficient to effect gelation of said ointment and selected from the group consisting of a cellulose compound and a carboxyvinyl polymer which has been neutralized with aqueous ammonia or an amine; (c) an adjuvant being present in the range of from 0.5 to 5% by weight and selected from the group consisting of a C.sub.1 -C.sub.5 alcohol ester of a C.sub.4 -C.sub.14 monocarboxylic acid and a C.sub.1 -C.sub.3 alcohol diester of a C.sub.4 -C.sub.
    Type: Grant
    Filed: February 22, 1983
    Date of Patent: June 25, 1985
    Assignee: Kowa Company Limited
    Inventors: Toshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
  • Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same
    Patent number: 4522826
    Abstract: Novel pharmaceutical compositions of matter are provided comprising analgesic/non-steroidal anti-inflammatory drugs and diphenhydramine and methods of using said compositions to elicit an enhanced analgesic and/or anti-inflammatory response in mammalian organisms in need of such treatment.
    Type: Grant
    Filed: February 8, 1984
    Date of Patent: June 11, 1985
    Assignee: Richardson-Vicks Inc.
    Inventors: Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
  • Watersoluble derivatives of non-steroidal anti-inflammatory agents and a process for the production thereof
    Patent number: 4518608
    Abstract: The invention relates to watersoluble derivatives of non-steroidal anti-inflammatory drugs and also to therapeutic compositions containing these derivatives.
    Type: Grant
    Filed: April 20, 1983
    Date of Patent: May 21, 1985
    Assignee: Medimpex Gyogyszerkuelkereskedelmi Vaallalat
    Inventor: Agostne Kahan