Tocopherols (e.g., Vitamin E, Etc.) Patents (Class 514/458)
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Patent number: 8535659Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.Type: GrantFiled: May 21, 2009Date of Patent: September 17, 2013Assignee: Argent Development Group, LLCInventors: John C. Morrison, Kenneth R. Greathouse
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Patent number: 8535660Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.Type: GrantFiled: November 7, 2011Date of Patent: September 17, 2013Assignee: Argent Development Group, LLCInventors: John C. Morrison, Kenneth R. Greathouse
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Patent number: 8536220Abstract: The present invention relates to a dietary supplement composition made of: linolinic expeller pressed soybean oil in the range of 65%-85%, Omega 3 (18/12) fish oil 15%-35%, and 1%-20% alpha-tocopherol and a method to use this composition to supplement the diet of a domestic animal, such as a canine or an equine.Type: GrantFiled: January 24, 2011Date of Patent: September 17, 2013Inventors: Murray Fulgham, Bruce Evans Wofford
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Publication number: 20130237613Abstract: The present invention relates to a thermodynamically stable, biocompatible, environment friendly, and temperature-insensitive microemulsion containing various botanical essential oils, sugar based surfactants, polyhydric alcohols, and an aqueous phase.Type: ApplicationFiled: September 4, 2012Publication date: September 12, 2013Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventor: Sanggu Kim
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Patent number: 8530519Abstract: Provided is a method for promoting upper gastrointestinal bicarbonate secretion in a mammalian subject, which comprises administering an effective amount of a compound of Formula (I): to a subject in need thereof, wherein W1, W2, R1, R2, x1, x2, Y and A are herein defined. The compound is also useful for protecting the upper gastrointestinal tract of a mammal from mucosal damage.Type: GrantFiled: November 23, 2010Date of Patent: September 10, 2013Assignee: Sucampo AGInventor: Ryuji Ueno
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Patent number: 8524696Abstract: Water-soluble compositions comprising a lipophilic compound and a solubilizing agent of the general formula: {X—OOC—[(CH2)n—COO]m}p—Y??(I) wherein: X is a residue of a hydrophobic moiety, Y is a residue of a hydrophilic moiety, p is 1 or 2, m is 0 or 1, and n is an integer greater than or equal to 0 are disclosed. The lipophilic compound is preferably selected from the group consisting of water-insoluble ubiquinones, ubiquinols, vitamins, provitamins, polyene macrolide antibiotics, and mixtures thereof. The hydrophobic moiety is preferably a sterol or a tocopherol and the hydrophilic moiety is preferably a polyalkylene glycol. In some embodiments, the sterol is cholesterol or sitosterol, the tocopherol is ?-(+)-tocopherol, the polyalkylene glycol is a polyethylene glycol or its methyl monoether having an average molecular weight between 400 and 1000, p is equal to 1 or 2, m is equal to 0 or 1 and n is an integer between 2 and 18.Type: GrantFiled: April 28, 2009Date of Patent: September 3, 2013Assignee: National Research Council of CanadaInventors: Henryk Borowy-Borowski, Marianna Sikorska-Walker, P. Roy Walker
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Publication number: 20130225521Abstract: A micronutrient dosage unit which comprises two or more micronutrients selected from vitamin A, vitamin B2, vitamin B6, vitamin B9, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, calcium, magnesium, zinc, boron and chromium in one or more specified ratios. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.Type: ApplicationFiled: April 9, 2013Publication date: August 29, 2013Inventor: Ralph BROWN
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Publication number: 20130210777Abstract: The present invention is directed to compositions and processes for their use that ameliorate the appearance of bruises, making them less cosmetically unappealing. The composition functions by acting both as a humectant and occlusive agent attracting water, returning the skin surface to a smooth state and holding water in place. The re-establishment of a homeostatic state in the skin results in a rapid dissipation of the negative cosmetic effects of the bruise on the skin.Type: ApplicationFiled: February 25, 2013Publication date: August 15, 2013Inventors: Bruce A. Cranner, Anne-Marie T. Karp, C. Scott Danos
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Patent number: 8492432Abstract: The invention provides compositions for preventing or treating kidney disease and improving kidney function comprising at least two ingredients selected from the group consisting of antioxidants and mitochondrial cofactors in amounts sufficient for preventing or treating kidney disease or for improving kidney function and methods for preventing and treating kidney disease or improving kidney function comprising administering such compositions to an animal susceptible to or suffering from kidney disease or impaired kidney function. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating kidney disease and improving kidney function, particularly in senior animals.Type: GrantFiled: August 17, 2006Date of Patent: July 23, 2013Assignee: Hill's Pet Nutrition, Inc.Inventors: Steven Curtis Zicker, Karen Joy Wedekind Lake
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Patent number: 8491937Abstract: The invention provides a multivitamin and mineral nutritional supplement composition comprising at least one polyvalent metal and at least one oxidizable vitamin with substantially improved resistance to reactions that lead to darkening and/or spotting and reactions that may reduce the potency of oxidizable vitamins. The composition is a multivitamin and mineral composition comprising at least one polyvalent metal and at least one oxidizable vitamin wherein the composition is substantially free of mobile bound water. The invention also includes methods for making such a composition and methods of preventing or reducing oxidation, improving the stability of oxidizable vitamins, and stabilizing the disintegration time of a multi-vitamin and mineral nutritional supplement composition.Type: GrantFiled: February 15, 2007Date of Patent: July 23, 2013Assignee: Wyeth LLCInventors: Alan M. Goldberg, Steven Dills, William Mark, Bruce Sutton, Chad Byerley
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Publication number: 20130183281Abstract: Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).Type: ApplicationFiled: April 20, 2012Publication date: July 18, 2013Inventors: Shin-San Michael Su, Lenny Dang, Stefan Gross, Shengfang Jin, Valeria Fantin
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Patent number: 8486374Abstract: A waterless composition suitable for delivery of an active agent to a body surface or cavity includes a vehicle having about 70% to about 99% by weight of a hydrophilic polar solvent, said hydrophilic solvent selected from the group consisting of (i) a mixture of two or more different polyethylene glycols (PEGs), wherein at least one PEG is a high molecular weight PEG having a melting point greater than 25° C.; and (ii) propylene glycol (PG); about 0% to about 10% of at least one surface active agent; about 0% to about 5% of a polymeric agent; about 0% to about 30% of a secondary hydrophilic solvent; and about 0% to about 5% of a silicone oil; and about 3% to about 25% hydrophobic propellant. The composition is otherwise substantially free of a hydrophobic solvent and includes at least one of a surface active agent and a polymeric agent. The vehicle and the propellant are sufficiently miscible that the components may be homogeneously distributed with mild shaking.Type: GrantFiled: January 14, 2008Date of Patent: July 16, 2013Assignee: Foamix Ltd.Inventors: Dov Tamarkin, Meir Eini, Doron Friedman, Alex Besonov, David Schuz, Tal Berman, Jorge Danziger, Rita Keynan, Ella Zlatkis
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Publication number: 20130178519Abstract: A process for the extraction of Vitamin E from annatto plant matter is disclosed wherein annatto seed matter is subjected, before extraction, to acidification using amla fruit matter. After the acidification, the mixture of the two plant matters is extracted by water. The acidification converts the vitamin E compounds in the plant matter into more water-soluble forms thus enhancing the vitamin yield. More of the vitamin is obtained in the ester form than in the form of vitamin alcohols. Processing time is reduced.Type: ApplicationFiled: July 30, 2012Publication date: July 11, 2013Inventors: Rajendran Ramaswamy, Kamala Ramaswamy
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Publication number: 20130178518Abstract: The instant invention pertains to a method for producing contact lenses with improved oxidative stability of Carotenoids in the contact lens. The method of the invention involves adding a vitamine E material into a contact lens in an amount sufficient to reduce oxidative degradation of Carotenoids in the lens by at least about 30% in comparison with an identical contact lens without the vitamin E material.Type: ApplicationFiled: December 17, 2012Publication date: July 11, 2013Applicant: NOVARTIS AGInventor: Novartis AG
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Patent number: 8476192Abstract: An aqueous seed treatment insecticidal and/or nematicidal composition in the form of a suspension comprising (A) at least one insecticide and/or nematicide in an amount of at least 3 weight %, based on the total weight of the composition, and (B) at least two surface active compounds, wherein (i) at least one is an anionic phosphate type compound, and (ii) at least one is a non-ionic alkoxylated phenol. Such compositions demonstrate improved dust-off performance when applied to plant propagation material, such as seeds.Type: GrantFiled: March 15, 2005Date of Patent: July 2, 2013Assignee: Syngenta Crop Protection LLCInventors: Lear Michael Haulsee, Humberto B. Lopez
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Publication number: 20130165435Abstract: Compositions of matter including (R)-2,5,6,8-tetramethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-1,2,3,8,9,10-hexahydrochromeno[5,6-e][1,3]oxazine and (R)-2,6,8-trimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-1,2,3,8,9,10-hexahydrochromeno[5,6-e][1,3]oxazine are disclosed herein. Further disclosed are methods of preparation of such compounds and the use of such compounds as anticancer agents.Type: ApplicationFiled: November 30, 2012Publication date: June 27, 2013Inventors: Khalid A. El Sayed, Paul W. Sylvester, Fathy A. Behery
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Patent number: 8470873Abstract: The present invention provides vitamin E succinate (VES)-stabilized compositions, methods for the preparation thereof and methods useful for the in vivo delivery of substantially water insoluble and optionally chemically unstable pharmacologically active agents (such as docetaxel).Type: GrantFiled: February 1, 2007Date of Patent: June 25, 2013Assignee: Mast Therapeutics, Inc.Inventor: Andrew Xian Chen
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Patent number: 8470876Abstract: The present invention provides lipid compositions comprising linolenic acid (LA), alpha-linolenic acid (ALA), stearidonic acid (SDA) and gamma linolenic acid (GLA), said LA and ALA in a ratio of about less than 2:1 LA:ALA. The compositions find use in for improving, treating, or preventing a condition selected from the group consisting of: eczema, dry skin, flaky skin, pruritus, pyotraumatic dermatitis, furunculosis, dry paw pads, rough paw pads, chapped paw pads, paw pad durability, dry rhinarium, chapped rhinarium, split claws, brittle claws, rashes, hairless spots, hot spots, symmetrical lupoid onychodystrophy, skin ulceration, skin crusting, reddening of skin between toes, external ear infection, and nutritional dermatosis.Type: GrantFiled: December 11, 2009Date of Patent: June 25, 2013Assignee: Olini LtdInventors: Inge Bruheim, Mikko Griinari
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Patent number: 8470880Abstract: The present disclosure relates to methods of retarding hair loss or facilitating hair growth and/or regrowth. More specifically, the present disclosure relates to methods of using the disclosed compositions to increase the rate of terminal hair growth and/or regrowth in a mammal.Type: GrantFiled: December 15, 2009Date of Patent: June 25, 2013Assignee: McNeil-PPC, Inc.Inventors: Longsheng Hu, Virginia Streusand Goldman, Josephine A. Minerva, Susan Wendling
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Patent number: 8470833Abstract: The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.Type: GrantFiled: December 15, 2009Date of Patent: June 25, 2013Assignee: McNeil-PPC, Inc.Inventors: Longsheng Hu, Virginia Streusand Goldman, Josephine A. Minerva, Susan Wendling
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Publication number: 20130149386Abstract: A method is provided for early treatment of steatosis, which method is based on early detection of steatosis based on the detection of CD36. CD36 is determined in a body fluid, and CD36 levels above a predetermined value is indicative of steatosis.Type: ApplicationFiled: December 7, 2012Publication date: June 13, 2013Applicant: REGION NORDJYLLANDInventor: REGION NORDJYLLAND
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Publication number: 20130142768Abstract: The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of rosemary, rosemary extract, coffeic acid, coffee extract, turmeric extract, cucurmin, blueberry extract, grapeseed extract, rosemarinic acid, tea extract, and mixtures thereof.Type: ApplicationFiled: February 1, 2013Publication date: June 6, 2013Applicant: THE IAMS COMPANYInventor: The IAMS Company
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Patent number: 8455006Abstract: An organic hair care composition made from organic ingredients, such as vegetable emulsifying wax, olive oil, shea butter, jojoba oil, and beeswax. The organic ingredients are mixingly introduced in predetermined proportions necessary to effectuate the styling, straightening, and therapeutic revitalization of hair in accordance with the included methods of manufacturing and use.Type: GrantFiled: November 4, 2010Date of Patent: June 4, 2013Inventor: Anika Lee Thompson-Staples
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Publication number: 20130137651Abstract: The present invention relates to a solid powder composed of a mixture of a natural or a synthetic polymer which forms a gel, a buffer, such as an hydroxyacid or a dicarboxyacid, a saccharide, one or more drugs useful for the treatment of diseases of the eyes and optionally one or more excipients and/or regulators of the osmotic pressure ophthalmologically acceptable.Type: ApplicationFiled: January 25, 2013Publication date: May 30, 2013Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.Inventor: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
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Publication number: 20130123214Abstract: This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of delta tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol in combination with cyclodextrin to a patient in need thereof.Type: ApplicationFiled: July 19, 2011Publication date: May 16, 2013Applicant: The United States of America as Represented by the Secretary Department of HRInventors: Wei Zheng, Juan Jose Marugan, Ke Liu, Noel Terrence Southall, Christopher P. Austin
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Publication number: 20130116314Abstract: A phytochemical composition for use as a veterinary dietary supplement comprising alpha linolenic acid (ALA) and up to 10% gamma linolenic acid (GLA). Preferably the ALA source is flax seed oil and GLA is sourced from borage oil.Type: ApplicationFiled: October 29, 2012Publication date: May 9, 2013Applicant: Lintbells Ltd.Inventor: Lintbells Ltd.
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Patent number: 8435544Abstract: The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or condition using the disclosed compositions. According to aspects illustrated herein, there is provided a pharmaceutical composition that includes a calcineurin inhibitor or an mTOR inhibitor; a first surfactant with an HLB index greater than about 10; and a second surfactant with an HLB index of greater than about 13, wherein an absolute difference between the HLB index of the first surfactant and the HLB index of the second surfactant is greater than about 3, and wherein the composition forms mixed micelles.Type: GrantFiled: October 8, 2008Date of Patent: May 7, 2013Assignee: Lux Biosciences, Inc.Inventors: Ashim K. Mitra, Poonam R. Velagaleti, Subramanian Natesan
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Publication number: 20130108573Abstract: Provided herein are methods of treating or ameliorating hypercholemia or a cholestatic liver disease by administering to an individual in need thereof a therapeutically effective amount of an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt thereof. Also provided are methods for treating or ameliorating a liver disease, decreasing the levels of serum bile acids or hepatic bile acids, treating or ameliorating pruritis, reducing liver enzymes, or reducing bilirubin comprising administering to an individual in need thereof a therapeutically effective amount of ASBTI or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 26, 2012Publication date: May 2, 2013Applicant: Lumena Pharmaceuticals, Inc.Inventor: Lumena Pharmaceuticals, Inc.
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Publication number: 20130101644Abstract: Vitamin E compositions, methods of making such compositions and therapeutic uses of vitamin E compositions are disclosed. Compositions of matter comprising a tocotrienol making up at least 15 dry basis weight percent of the composition of matter and a constituent selected from a triglyceride and a triglyceride ester, wherein upon mixing of the composition of matter with water the tocotrienol based composition is substantially emulsified; and wherein upon mixing of the composition of matter with water a resulting emulsion has an intensity-weighed mean droplet size of less than 700 nm are also disclosed.Type: ApplicationFiled: October 19, 2012Publication date: April 25, 2013Inventors: Sami Mahmoud Nazzal, Paul W. Sylvester, Alaadin Y. Alayoubi
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Publication number: 20130096190Abstract: A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses.Type: ApplicationFiled: November 29, 2012Publication date: April 18, 2013Applicant: OXYGEN BIOTHERAPEUTICS, INC.Inventor: OXYGEN BIOTHERAPEUTICS, INC.
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Publication number: 20130084272Abstract: The present invention relates to compositions, kits and methods for the administration of compositions and kits for supplementation with twelve carbon chain fatty acids or twelve carbon chain acylglycerols; and specifically for the supplementation with twelve carbon chain fatty acids such as lauric acid and twelve carbon chain acylglycerols such as monolaurin; and specifically for the co-supplementation with other vitamins, minerals and nutrients.Type: ApplicationFiled: September 29, 2011Publication date: April 4, 2013Inventors: Philippe PERRIN, Guillaume HERRY, Cecile BOYER-JOUBERT
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Publication number: 20130078320Abstract: A composition to be administered to a mammal for treating hearing loss is disclosed herein. The composition consists essentially of a biologically effective amount of vitamin A, vitamin C, vitamin E, and a vasodilator comprising magnesium. The composition optionally includes a withanolide and/or resveratrol. The vitamin A, vitamin C, vitamin E, and the vasodilator comprising magnesium provides an additive effect that is equal to or greater than a sum of the effects of the individual components.Type: ApplicationFiled: November 16, 2012Publication date: March 28, 2013Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventor: The Regents of the University of Michigan
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Publication number: 20130079395Abstract: The present invention provides a process for the production of an oil in water emulsion comprising the step of a) introducing an oil phase into a mixing device by applying a positive pressure in the oil phase containing tank.Type: ApplicationFiled: June 8, 2011Publication date: March 28, 2013Applicant: GlaxoSmithKline Biologicals S.A.Inventors: Vinciane De Cupere, Vincent Mancuso
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Patent number: 8404265Abstract: An appliance for the delivery of at least one bioactive agent to the eye has at least one diffusion attenuator within a hydrophilic or silicone-hydrogel contact lens. The bioactive agent can be a drug or a nutraceutical. The diffusion attenuator can be a plurality of solid particles or phase separated liquid aggregates within at least one continuous phase of the lens where the diffusion attenuators promote a tortuous path for the diffusion of the bioactive agent to mediate the rate by which the bioactive agent diffuses from the contact lens. The diffusion attenuator can be homogeneously dispersed throughout at least one continuous phase of the lens to modify the diffusivity of the bioactive agent through that phase. The diffusion attenuator can have little or no affinity for the bioactive agent or can be miscible with the bioactive agent. The diffusion attenuator can be incorporated while forming the contact lens by polymerization of a monomer mixture containing the diffusion attenuator.Type: GrantFiled: July 22, 2010Date of Patent: March 26, 2013Assignee: University of Florida Research Foundation, Inc.Inventors: Anuj Chauhan, Jinah Kim
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Publication number: 20130071372Abstract: Metallo-proteins including but not limited to lactoferrin (LF), transferrin (TF) and ovotransferrin (OTF) (all members of transferrin family), ceruloplasmin (CP) and metallo-thionein (MT) were found to stabilize and enhance the bio-functional activity of tocotrienol (T3), T3 mixtures or derivates. The synergism between MP and T3 also promote the intestinal transfer and the ultimate bio-availability of T3 and T3-derivatives for physiological functions. Such functional synergism includes hypocholesterolemic, anti-thrombotic, antioxidant, anti-athermogenic, anti-inflammatory and immuno-regulatory activities of T3 agents. Addition of a non-protein-type metal chelator provided further improvement in the action of the bio-functional activity of T3. These T3 compositions are useful as pharmaceuticals, in cosmetics, in foods and as nutritional supplements.Type: ApplicationFiled: November 9, 2012Publication date: March 21, 2013Applicant: Naidu LPInventor: Naidu LP
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Publication number: 20130058878Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.Type: ApplicationFiled: April 7, 2011Publication date: March 7, 2013Applicant: SEDERMAInventors: Arnaud Fournial, Philippe Mondon, Olivier Peschard
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Publication number: 20130053353Abstract: The present disclosure relates generally to compositions for cosmetic or pharmaceutical application. The compositions include a carrier and rheology modulators.Type: ApplicationFiled: May 4, 2011Publication date: February 28, 2013Applicant: FOAMIX LTD.Inventors: Dov Tamarkin, Elana Gazal, Yohan Hazot, David Schuz
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Publication number: 20130052234Abstract: An edible oral strip composition includes a therapeutically effective amount of active agent(s) to provide at least one effect selected from a stimulating effect, an increased physical endurance, alleviate temporary fatigue, improve nervous system functions, and combinations of any of the foregoing. In additional embodiments, the edible strip composition includes a therapeutically effective amount of active agent(s) to provide sleep aid.Type: ApplicationFiled: August 3, 2012Publication date: February 28, 2013Applicant: Purebrands LLCInventors: Michael Goldberg, Ehud Arbit
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Publication number: 20130039961Abstract: A personal care composition is disclosed comprising abrasive particles. The personal care composition may take a variety of forms such as a leave-on composition or an emulsion and/or may comprise one or more actives or agents.Type: ApplicationFiled: June 20, 2012Publication date: February 14, 2013Inventors: Denis Alfred GONZALES, Martin Ian James, Geert Andre Deleersnyder, Steven Ray Merrigan, Thomas Allen Desmarais, Paul Robert Tanner, Binwu Tao
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Publication number: 20130041024Abstract: The invention relates to methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions, particularly arthritis and joint pain, in canines, comprising measuring inflammatory biomarkers wherein elevated levels of the biomarkers in blood correlates to reduced inflammation and reduced levels in blood correlates to increase level in the tissues. The invention further provides a method to treat or control inflammation comprising administering a diet comprising increased levels of one or more of DHA, EPA, vitamin C, vitamin E, and/or L-carnitine.Type: ApplicationFiled: May 5, 2011Publication date: February 14, 2013Applicant: Hill's Pet Nutrition, Inc.Inventor: Nolan Zebulon Frantz
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Patent number: 8372825Abstract: Skin compositions comprising, hydrocortisone; allantoin; and a water-based vehicle that is essentially free of petroleum jelly, mineral oil and wax; and related method for protecting, healing and/or soothing the skin comprising: applying an effective amount of a cosmetic preparation selected from the group consisting of hand cream, foot cream, body cream, lip cream, lip gloss, lip stick, gel, balm and lotion to the skin surface; wherein said cosmetic preparation includes a skin composition made of hydrocortisone; allantoin; and a water-based vehicle that is essentially free of petroleum jelly, mineral oil and wax; and said effective amount is enough to protect, heal and/or soothe the skin surface.Type: GrantFiled: August 13, 2009Date of Patent: February 12, 2013Inventor: Norman Turkowitz
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Patent number: 8367085Abstract: Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: idebenone; N-acetylcysteine, and alpha-tocotrienol or an ester thereof with a C2-C4 organic acid.Type: GrantFiled: June 21, 2011Date of Patent: February 5, 2013Assignee: LVMH RechercheInventors: Patrice Andre, Isabelle Renimel, Céline Godenir, Michel Hocquaux
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Patent number: 8362078Abstract: The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine metabolism selected from the group consisting of vitamin B12 and precursors thereof, vitamin B6 and derivatives thereof, folic acid, zinc and magnesium, in the manufacture of a preparation for improving the action of receptors. This preparation is advantageously applied in patients suffering from Parkinson's disease, Huntington's chorea, epilepsy, schizophrenia, paranoia, depression, sleep disorders, impaired memory function, psychoses, dementia and ADHD.Type: GrantFiled: December 1, 2008Date of Patent: January 29, 2013Assignee: N.V. NutriciaInventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
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Patent number: 8361520Abstract: Antioxidant skin care composition comprising at least two antioxidant components one of which is a solid coffee extract antioxidant, which exhibits a synergistically increased antioxidant potency as measured by ORACsc compared to the antioxidant potency of antioxidant skin care compositions which do not contain at least two antioxidant components one of which is a solid coffee extract antioxidant. The skin care compositions are particularly suited for use in the treatment of wrinkles, pigmentation effects caused by sun damage and redness in the skin.Type: GrantFiled: October 8, 2010Date of Patent: January 29, 2013Inventor: Debbie M. Palmer
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Patent number: 8361512Abstract: Provided are methods and compositions for increasing CD4+ cell count in mammals, preferably by at least 25%, while undergoing treatment for various conditions whose treatment can have detrimental effects on immune system function. Such conditions include, but are not limited to, HIV infection, cancer, and hepatitis. The compositions include alpha lipoic acid; acetyl L-carnitine; N-acetyl-cysteine; zinc; selenium; vitamin C; bioflavinoid complex; vitamin E; optionally one or more antioxidants selected from co-enzyme Q10 and glutathione; and one or more vitamins or minerals selected from beta-carotene, vitamin A, vitamin B1, vitamin B2, vitamin B6, niacinamide, calcium pantothenate, folic acid, vitamin B12, copper, manganese, chromium, and molybdenum.Type: GrantFiled: May 27, 2011Date of Patent: January 29, 2013Assignee: K-PAX Vitamins, Inc.Inventor: Jon D. Kaiser
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Patent number: 8362071Abstract: Vitamin E succinate derivatives according to formula I: are described. These compounds can be included in pharmaceutical compositions, and can be used for the treatment of cancers such as metastatic cancer and as antiadhesive agents.Type: GrantFiled: April 16, 2010Date of Patent: January 29, 2013Assignee: The Ohio State University Research FoundationInventors: Ching-Shih Chen, Dasheng Wang, Samuel K. Kulp
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Publication number: 20130011347Abstract: Personal care compositions are disclosed comprising an isosorbide diester having the formula: wherein R? and R? are independently selected from a straight or branched C1-30 chain, which may be saturated or unsaturated. The personal care compositions also comprise a solid cosmetic active soluble in the isosorbide diester and a dermatologically acceptable carrier. The personal care composition may be in the form of an emulsion. A personal care composition is also disclosed comprising an isosorbide diester having the formula: wherein R? and R? are independently selected from a straight or branched C1-30 chain which may be saturated or unsaturated and Z1-Z6 are independently selected from hydrogen, hydroxyl, amino, amido, R?, or R?. Methods of making the aforementioned personal care compositions are also disclosed.Type: ApplicationFiled: July 7, 2011Publication date: January 10, 2013Inventors: Paul Robert Tanner, Larry Richard Robinson
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Publication number: 20130011498Abstract: The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5 ?-3), FOS, carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and subtantially lacking in free amino acids.Type: ApplicationFiled: January 11, 2012Publication date: January 10, 2013Applicant: ABBOTT LABORATORIESInventors: Jeffrey H. Baxter, Anne C. Voss, Pradip Mukerji, Michael J. Tisdale
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Patent number: 8344022Abstract: The invention provides compositions and methods for increasing cell growth, stimulating cell turnover and promoting the secretion of mucus within the reproductive tract of a female mammal.Type: GrantFiled: February 3, 2009Date of Patent: January 1, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Julie M. Villanueva, Sohail Malik
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Publication number: 20120329864Abstract: A transdermal fluid is provided wherein the main ingredient is tocotrienol, and curcumin is added to enhance the anti-cancer effects of tocotrienols. The composition is useful for the treatment or prevention of a cancer, a tumour or an inflammatory disorder, particularly breast cancer.Type: ApplicationFiled: March 8, 2011Publication date: December 27, 2012Applicant: MALAYSIAN PALM OIL BOARDInventors: Kalanithi Nesaretnam, Kanga Rani Selvaduray