Abstract: A controlled pesticide delivery system includes a film-forming alkanol solution of at least one amphiphilic polymer and at least one pesticide composition for the treatment of at least one pest in gardens, landscapes, forests, and wooden structures, targeting at least one pest selected from fire ants, tent caterpillars, gypsy moths, wood-boring beetles, and bark beetles during at least one phase of their life cycles.

Abstract: An improved pesticide delivery system is disclosed. The system is based on a microblend comprising (a) an amphophilic compound containing at least one hydrophilic group and at least one hydrophobic group and (b) a second compound. Compositions based on the microblend and methods of using the compositions to control pests are also disclosed.

Abstract: Method of controlling insects with a gel or foam formulation containing at least one insecticidal active substance, characterized in that the agrochemical formulation is applied externally to the trunk of the plant to be protected.

Abstract: Volatile impregnated substrates, such as wicks and mats, that can be used in a dispensing device that uses a heat source or otherwise uses active means to promote the release of the volatile material from the substrate are disclosed. The preferred substrate has a structure including sand particles adhered together by a binder to form a network of pores and passages. The binder is selected from thermoset polymeric materials and mixtures thereof. A volatile material is disposed in the pores before the substrate is installed in the dispensing device. The impregnated substrate is positioned in the dispensing device on or near the heat source of the dispensing device. The heat source is activated thereby elevating the temperature of the substrate such that volatile material is released from the pores. In one embodiment, the sand particles comprise silica sand and the binder is a cured novolac resin.

Abstract: Volatile impregnated substrates, such as wicks and mats, that can be used in a dispensing device that uses a heat source or otherwise uses active means to promote the release of the volatile material from the substrate are disclosed. The preferred substrate has a structure including sand particles adhered together by a binder to form a network of pores and passages. The binder is selected from thermoset polymeric materials and mixtures thereof. A volatile material is disposed in the pores before the substrate is installed in the dispensing device. The impregnated substrate is positioned in the dispensing device on or near the heat source of the dispensing device. The heat source is activated thereby elevating the temperature of the substrate such that volatile material is released from the pores. In one embodiment, the sand particles comprise silica sand and the binder is a cured novolac resin.

Abstract: A method of inhibiting excitotoxicity by indirectly activating ?4?2 nicotinic acetylcholine receptors (nAChRs) which indirectly activate synaptic AMPA and NMDA receptors is disclosed. Inhibitors of ?7 nACHRs, such as macrocyclic diterpenoids, more specifically cembranoids or methyllycaconitine (MLA), indirectly activate ?4?2 nAChRs and can be used to treat neurodegenerative diseases, including, but not limited to, Alzheimer's Disease, Parkinson Disease, AIDS related dementia and the delayed effects of stroke. They can also be used to treat diseases associated with neuronal impairment, including, but not limited to glaucoma caused by optical nerve damage, delayed effects of epilepsy; and multiple sclerosis.

Abstract: Volatile impregnated substrates, such as wicks and mats, that can be used in a dispensing device that uses a heat source or otherwise uses active means to promote the release of the volatile material from the substrate are disclosed. The preferred substrate has a structure including sand particles adhered together by a binder to form a network of pores and passages. The binder is selected from thermoset polymeric materials and mixtures thereof. A volatile material is disposed in the pores before the substrate is installed in the dispensing device. The impregnated substrate is positioned in the dispensing device on or near the heat source of the dispensing device. The heat source is activated thereby elevating the temperature of the substrate such that volatile material is released from the pores. In one embodiment, the sand particles comprise silica sand and the binder is a cured novolac resin.

Abstract: The present invention relates to novel renin inhibitors of the general Formula (I), and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds. These novel renin inhibitors are used in treating cardiovascular events and renal insufficiency.

Abstract: The present invention provides a granular pesticide composition which is highly effective in controlling pests. In particular, the pesticide composition of the present invention is prepared by adsorbing an oil in water emulsion on inert granular particles. These compositions provide improved release of the pesticide. Methods of preparing the granular pesticide composition and methods of use thereof are disclosed.

Abstract: The present invention relates to a method for controlling arthropods by indirect contact action using the pesticides mentioned in the description.

Abstract: Pesticide concentrates are provided containing an emulsifier that is an EPA list 4 inert and is a polyglycerol fatty acid ester, a sorbitan fatty acid ester or a combination thereof, a pesticide and a solvent that is either a EPA list 3 inert of acetyl ester, EPA list 4 inert of a methyl fatty ester, an acetyltributyl citrate, white mineral oil or a combination thereof. The pesticide can be a water-insoluble synthetic pyrethroid, natural pyrethrum, channel blocking insecticide, acetylcholinesterase inhibitor, oxadiazine, organophosphate, neonicotinoid insecticide, thiamethoxam, imidacloprid, acetamiprid, thiacloprid, clothianidin, nitenpyran, insect growth regulator, juvenile hormone mimic, fermentation insecticide, plant oil insecticide acaracide, miticide, fungicide, herbicide and combinations thereof. The pesticide concentrate is diluted with a hydrocarbon solvent, a white mineral oil or a combination thereof and mixed with water.

Abstract: A two-layered olefin-based resin pellet comprising a core layer formed of an olefin-based resin composition (A) and a sheath layer formed of an olefin-based resin composition (B) and laminated on the outer surface of the core layer, wherein said olefin-based composition (A) contains an insecticidal compound, a granular inorganic filler, a metal soap, and an olefin-based resin (a) having a relatively high solubility to the insecticidal compound; and said olefin-based resin composition (B) contains, as a main component, an olefin-based resin (b) having a relatively low solubility to the insecticidal compound.

Abstract: An improved pesticide delivery system is disclosed. The system is based on a microblend comprising (a) an amphiphilic compound containing at least one hydrophilic group and at least one hydrophobic group and (b) a pesticide. Compositions based on the microblend and methods of using the compositions to control pests are also disclosed.

Abstract: Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils and/or their constituents, plant essential oils and/or their constituents in admixture with known active pesticidal compounds or plant essential oils and/or their constituents in admixture with other compounds not previously used as active ingredients in pesticidal formulations, such as, for example, so called signal transduction modulators. In addition, the present invention is directed to a method for controlling pests by applying a pesticidally effective amount of the above synergistic and residual pesticidal compositions to a locus where pest control is desired.

Abstract: The present invention is directed to novel insecticidal and/or miticidal compositions comprising bifenthrin and a cyano-pyrethroid. The compositions exhibit an unexpected increase in insecticidal activity as compared to the insecticidal activity of the individual components.

Abstract: Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils and/or their constituents, plant essential oils and/or their constituents in admixture with known active pesticidal compounds or plant essential oils and/or their constituents in admixture with other compounds not previously used as active ingredients in pesticidal formulations, such as, for example, so called signal transduction modulators. In addition, the present invention is directed to a method for controlling pests by applying a pesticidally effective amount of the above synergistic and residual pesticidal compositions to a locus where pest control is desired.

Abstract: Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils and/or their constituents, plant essential oils and/or their constituents in admixture with known active pesticidal compounds or plant essential oils and/or their constituents in admixture with other compounds not previously used as active ingredients in pesticidal formulations, such as, for example, so called signal transduction modulators. In addition, the present invention is directed to a method for controlling pests by applying a pesticidally effective amount of the above synergistic and residual pesticidal compositions to a locus where pest control is desired.

Abstract: Insecticidal compositions having insecticide and disinfectant activity are provided. Preferably, the insecticidal composition contains both an insect control agent and a disinfectant. Particularly low levels (i.e., below 20%) of at least one hydrocarbon are introduced as a solvent. The insecticidal compositions further comprise an emulsifier, buffer and antifoaming agent. These insecticidal compositions are particularly suitable for delivery in a spray for non-industrial environments. In use, the present insecticidal compositions may be applied directly to or in or around any area where it is desired to control pestiferous insects and the fungi, bacteria, viruses and other contaminants associated with them.

Abstract: Disclosed are compositions and methods related to powder and granular emulsifiable concentrate pesticide formulations. As disclosed, emulsions from non-aqueous based liquid or solvent soluble pesticide actives may be prepared using a high purity, high molecular weight sulfonated lignin as the emulsion stabilizer. The resulting emulsions may then be dried to obtain a powder or granular emulsion concentrate where the high molecular weight sulfonated lignin acts as a solid matrix for the pesticide active. The powder or granular emulsifiable concentrate formulations thus formed have high loading rates, good storage properties and are easily reconstituted when added to water.

Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.

Abstract: Embodiments of the present invention provide compositions for controlling a target pest including a pest control product and at least one active agent, wherein: the active agent can be capable of interacting with a receptor in the target pest; the pest control product can have a first activity against the target pest when applied without the active agent and the compositions can have a second activity against the target pest; and the second activity can be greater than the first activity.

Abstract: The present invention comprises methods for reducing plasma lipids, plasma free fatty acids (FFA), plasma glycerol and triglycerides in a mammal through the administration of certain substituted cyclopropane acid derivatives of Formula 1: wherein R1-R6 are defined herein and pharmaceutical compositions comprising them.

Abstract: The present invention discloses methods of using of compounds for the enhancement of the innate immune system of a patient. In particular, the active compounds of the present invention include at least one calcineurin inhibitor, mTOR inhibitor or non-immunosuppresive derivative, or a derivative, isomer, or pharmaceutically acceptable salt thereof; and optionally, at least one calciferol or LMW inhibitor, or a derivative, isomer, or pharmaceutically acceptable salt thereof. Pharmaceutical formulations comprising same are also disclosed.

Abstract: An aerosol-based insecticide composition comprising an active ingredient, such as deltamethrin, and a suitable carrier is disclosed as well as a method for its use. The insecticide composition may optionally contain one or more surfactants. Deltamethrin is preferably used as the active ingredient in the insecticide composition because of its tolerance for use on food. Furthermore, it has also been determined that deltamethrin is non-repellant to termites.

Abstract: The invention relates to process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid water-insoluble particulate matter with a cationic additive in an aqueous medium to obtain a dispersion of said particulate matter having a positive zeta potential; (b) coating the solid water-insoluble particulate matter by precipitation of a metal oxide salt onto the surface of the particulate matter, forming a metal oxide layer thereon; and (c) aging said coating layer The invention further relates to coated particulate matter obtained by the process and to compositions comprising solid, water-insoluble particulate matter, coated by a metal oxide layer, the particulate matter being a dermatological active agent or a pesticide. The invention additionally relates to methods of treating a surface condition in a subject using compositions comprising solid, water insoluble dermatologically active agent, coated by a metal oxide layer.

Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.

Abstract: An article (11) for providing a physical and chemical barrier to impede the penetration of insects through a passageway in a concrete slab (20), the article being adapted to reside in the passageway, between the slab and a member extending through the passageway.

Abstract: The present invention relates to an insecticidal composition of bifenthrin and acetamiprid with significantly improved knockdown and mortality characteristics when applied to general household pests.

Abstract: A carboxylic acid compound having cyclopropane ring(s) of the formula (I): wherein R is alkyl or alkenyl optionally having one or more 1,2-cyclopropylene in a carbon chain and/or optionally having cyclopropyl at the end of a chain,X is a single bond or alkylene, wherein the total number of carbon less the number of cyclopropane ring is 10-25, and a pharmaceutically acceptable salt thereof are provided. The compound (I) shows an LTP-like potentiation of synaptic transmission, allows slow metabolism in the living body, show a stable LTP-like potentiation of synaptic transmission, and is useful as an agent for LTP-like potentiation of synaptic transmission, a cognition-enhancing drug or an agent for the prophylaxis and treatment of dementia, a learning and memory disorder and a neurotransmitter release disorder.

Abstract: Agrochemical formulation comprising at least one room-temperature-solid active substance from the class of the neonicotinoids, at least one room-temperature-solid active substance from the class of the pyrethroids, at least one penetrant, at least one vegetable oil, cyclohexanone, at least one nonionic surfactant and/or at least one anionic surfactant, and one or more additives, process for producing it, and its use for controlling harmful organisms.

Abstract: An encapsulated composition of (a) a pesticide at least active via ingestion that is photolabile, and (b) at least one photoprotectant, wherein the encapsulating polymeric barrier is base triggerable is disclosed. A method for controlling damage of a material by a pest by the use of such encapsulated compositions is likewise disclosed. The composition as disclosed gives protection for beneficial arthropods and reduces workers exposure.

Abstract: A cartridge for insecticide transpiration includes an annular hollow structure which has openings in the inner peripheral surface and an outer peripheral surface thereof; a core portion situated at the center of the hollow structure for connecting to the rotation support shaft; a plurality of spoke portions connecting the core portion and the hollow structure; and blade portions integrally formed with the hollow structure so as to extend from the inner peripheral surface toward the center thereof and adapted to promote passing of air from the inner peripheral surface to the outer peripheral surface of the hollow structure, and; an insecticide transpiration apparatus wherein a cartridge for insecticide transpiration accommodating granular chemical-impregnated material 3 in the hollow structure is connected to a motor through the rotation support shaft and the cartridge for insecticide transpiration.

Abstract: Disclosed are novel compound of formula I, As defined herein and their use as pharmaceutically active compounds for reducing blood glucose, and/or treating one or more of type II diabetes, disturbances of lipid and carbohydrate metabolism, arteriosclerotic manifestations, and insulin resistance.

Abstract: The invention relates to a method for crop protection comprising administering to one or both of the crop and its environment a composition comprising a carrier; and microcapsules having a core material comprising a pesticide encapsulated by a silica shell, wherein the silica shell constitutes up to 10% w/w out of the total weight of the microcapsules, and wherein said administration gives rise to pesticide activity with immediate onset and prolonged effect. The invention further relates to a method for acute treatment of a pest-infested crop.

Abstract: An insecticidal composition which comprises an ester compound given by formula (1): [wherein R represents a methyl or methoxymethyl group] and 2,4,6-triisopropyl-1,3,5-trioxane as active ingredients, wherein the weight ratio of the ester compound to 2,4,6-triisopropyl-1,3,5-trioxane is 1:4000 to 1:4, is useful for controlling insects, especially insects which are harmful to fabric.

Abstract: The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the formula (I) and the active compounds identified in the disclosure.

Abstract: Pesticidal mixtures comprising, as active components 1) a compound of the formula I wherein W is CI or CF3; X and Y are each independently CI or Br; R1 is alkyl, alkenyl, alkynyl, or cycloalkyl optionally substituted with 1 to 3 halogens, or alkyl which is substituted by alkoxy; R2 and R3 are alkyl or may be taken together to form cycloalkyl optionally substituted by 1 to 3 halogens; R4 is H or C1-C8-alkyl, or the enantiomers or salts thereof, and a Compound II selected from organo(thio)phosphates, carbamates, pyrethroids, growth regulators, nicotinic receptor agonists/antagonists Compounds, GABA antagonist compounds, macrocyclic lactone insecticides, METI I acaricides, METI II and III compounds, uncoupler compounds, oxidative phosphorylation inhibitor compounds, moulting disrupter compounds, mixed function oxidase inhibitor compounds, sodium channel blocker compounds, and other various pesticide compounds.

Abstract: A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth.

Abstract: The present invention provides wherein R1 is selected from the group consisting of C1-C10 alkoxy, OH and NR4R5; R2 is selected from the group consisting of C1-C10 alkyl and (CH2)nOH; R3 is selected from the group consisting of C1-C10 alkyl, heteroaryl, e.g. thienyl, furanyl and pyridyl, phenyl, mono, -di-, tri-substituted phenyl and heteroaryl; R4 and R5 are independently selected from the group consisting of H, C1-C10 alkyl, C1-C10 alkyl hydroxyl; m is 0 or an integer from 1 to 3 and n is an integer of from 1 to 4. These compounds are useful in lowering intraocular pressure and/or treating glaucoma or providing neuroprotection to the eye of a human patient.

Abstract: Ticks and other arthropod ectoparasitic pests of birds may be effectively controlled and the populations of ticks on treated birds significantly reduced by affixing to the bird a leg band or wing tag containing a pesticide in an amount effective against the tick or other pest.

Abstract: A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth.

Abstract: The invention relates to aqueous insecticidal compositions embodied in the form of an aqueous polymer fine particle dispersion containing at least one type of organic insecticidal active substance whose water solubility is equal to or less than 5 g/l at 25° C./1013 mbar and a polymer particle average size, determined by dynamic light scattering, is equal to or less than 300 nm, wherein the polymer particles containing at least one insecticidal active substance exhibit a cationic surface charge and the aqueous dispersion of active substance containing polymer particles is obtained by radical aqueous emulsion polymerisation of an ethylenically unsaturated monomer composition M, in which said ethelenycally unsaturated monomer M contains at least one type of insecticidal active substance in a dissolved form. The use of the inventive aqueous insecticidal compositions for protecting lignocellulose-containing materials, in particular wood, against infest pest attacks is also disclosed.

Abstract: A topical formulation having significant parasiticidal activity effective against endoparasites and/or ectoparasites such as heartworms, mites, fleas, ticks, flies is provided, which can be safe to use and avoids the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of a macrocyclic lactone, a neo-nicotinoid and optionally, an insect growth regulator. The topical formulation can be packaged together or packaged so that the macrocyclic lactone and the neo-nicotinoid are stored separately prior to administering the topical insecticide formulation to the animal.

Abstract: Product for the treatment of household pets as having need of a therapeutic treatment, characterised in that it comprises, in separate form and intended to be mixed: a non-foaming base suited to constituting a galenic form for topical application and/or dermatological treatment, and a concentrated preparation of at least one component with reduced biological activity and suited to acquiring a maximum biological activity in relation to the desired treatment, under the effect of an appropriate change to the pH, advantageously to pH 6-7, whereas said at least one activable component with reduced biological activity is itself premixed with at least one foaming agent and as an option at least one emulsifier in said concentrated preparation, and whereas the pH of said concentrated preparation is either less than around 5 or more than 8, with as an option adjustment to this value by means of an appropriate buffer.

Abstract: Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils and/or their constituents, plant essential oils and/or their constituents in admixture with known active pesticidal compounds or plant essential oils and/or their constituents in admixture with other compounds not previously used as active ingredients in pesticidal formulations, such as, for example, so called signal transduction modulators. In addition, the present invention is directed to a method for controlling pests by applying a pesticidally effective amount of the above synergistic and residual pesticidal compositions to a locus where pest control is desired.

Abstract: A topical insecticide preparation is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. The topical insecticide contains a combination of a first pyrethroid insecticide effective for killing fleas, a second pyrethroid insecticide effective for killing ticks, and an insect growth regulator (IGR). The topical insecticide preparation can be packaged together or packaged so that the first and second pyrethroid insecticides are stored separately prior to administration of the insecticide preparation to the animal. The combination of the first and second pyrethroid insecticides with an insect growth regulator results in an insecticide preparation formulated to have enhanced insecticidal activity against fleas and ticks compared to the effectiveness of the first and second insecticides used alone.

Abstract: A combustible pesticidal product is disclosed which comprises a structural element formed from a cardboard having a thickness of at least 0.75 mm, a density of 450-850 kgm3 and consisting of 1 or more plies, the cardboard including: an alkali or alkaline earth metal nitrate or nitrite in an amount of from 0 to 1.83% w/w, or an alkali or alkaline earth carbonate or bicarbonate in an amount of from 0.02 to 7.0% w/w; one or more mineral silicates in an amount of from 0.01 to 8.0% w/w; a phosphate in an amount of from 0.01 to 0.40% w/w and selected from the group consisting of diammonium phosphate, monoammonium phosphate, triammonium phosphate and mixtures thereof; a boron compound in an amount of from 0.001 to 0.

Abstract: Aerosol insecticidal sprays are disclosed that contain butylhydroxytoluene, limonene, and sodium benzoate, in addition to water, hydrocarbon solvent, propellant, surfactant, and insecticidal active. The sprays are resistant to discoloration even during long term storage.

Abstract: A method and device are disclosed which prevent the intrusion of insects onto wood structures by using a barrier capable of retaining pesticide. In the disclosed method, the barrier maintains a minimal effective level of insecticide for a predetermined period of time.

Abstract: The present invention relates to the promotion of a continuous chemical barrier of a soil-born invertebrate pest control agent in soil in a locus where soil-borne invertebrate pests are suspected or known to exist. In particular the present invention relates to compositions of liquid soil-borne invertebrate pest control agents and selected adjuvants wherein the adjuvant improves the downward and lateral movement in the soil of the soil-born invertebrate pest control agent contained in the liquid soil-borne invertebrate pest control agent. The invention set forth herein finds particular utility with soil-born invertebrate pest control agents with a water solubility of 3 ppm, or less, such as bifenthrin.