Carboxylic Acid, Percarboxylic Acid, Or Salt Thereof (e.g., Peracetic Acid, Etc.) Patents (Class 514/557)
  • Patent number: 10307406
    Abstract: In an effort to discover therapies for treating diseases caused by EBV, a novel screening assay for identifying compounds that reactivate EBV latent infection and a family of small molecules based on a tetrahydrocarboline backbone were discovered. Specifically, the compounds have the structure of the formula (I), wherein R1-R11 are defined herein and activate/reactivate EBV in a variety of cell types in a patient and are, therefore, useful in preventing or treating EBV-positive cancer, optionally with an anti-viral agent. In screening these compounds, novel compositions, EBV-positive cell lines, and methods are provided.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: June 4, 2019
    Assignees: The Wistar Institute of Anatomy and Biology, Drexel University
    Inventors: Paul M. Lieberman, Nadezhda Tikhmyanova-Eckert, Joseph M. Salvino
  • Patent number: 10301263
    Abstract: The invention relates to pharmaceutical uses of compounds of formula (II). Particular aspects of the invention relate to the use of those compounds in treating, preventing or ameliorating a seizure-related disorder, bipolar disorder, mania, migraine, Alzheimer's disease, Parkinson's disease or stroke.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: May 28, 2019
    Assignee: Royal Holloway and Bedford New College
    Inventors: Robin Williams, Matthew Walker
  • Patent number: 10265289
    Abstract: The present invention provides an application of chlorogenic acid in preparing medicines for treating melanoma and a pharmaceutical composition comprising chlorogenic acid and used for treating melanoma.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: April 23, 2019
    Assignee: SICHU JIUZHANG BOPLOGICAL SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Jie Zhang, Xiaoguang Chen, Jun Huang, Wang Huang
  • Patent number: 10233149
    Abstract: The present invention relates generally to methods for forming peroxyformic acid, comprising contacting formic acid with hydrogen peroxide. The methods for forming peroxyformic acid can include adding formic acid with a relatively lower concentration of hydrogen peroxide, or adding formic acid to a peroxycarboxylic acid composition or forming composition to react with hydrogen peroxide in the compositions. The present invention also relates to peroxyformic acid formed by the above methods. The present invention further relates to the uses of peroxyformic acid for treating a variety of targets, e.g., target water, including target water used in connection with oil- and gas-field operations. The present invention further relates to methods for reducing or removing H2S or iron sulfide in the treated water source, improving clarity of the treated water source, or reducing the total dissolved oxygen or corrosion in the treated water source, using peroxyformic acid, including peroxyformic acid generated in situ.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: March 19, 2019
    Assignee: ECOLAB USA INC.
    Inventors: Ramakrishnan Balasubramanian, Junzhong Li, Richard Staub, Victor Keasler, Brian Bennett, Allison Brewster
  • Patent number: 10194656
    Abstract: Embodiments herein relate to animal feed preservatives including byproducts containing levulinic acid and methods of making and using the same. In an embodiment, a method of making an animal feed preservative is included. The method can include obtaining an acidic byproduct of a manufacturing process. The acidic byproduct can include at least about 1% by weight levulinic acid or a salt thereof. The method can further include mixing the acidic byproduct with a base to form the animal feed preservative. The animal feed preservative can include at least about 5 wt. % of the acid byproduct. In various embodiments, a method of reducing the amount of mycotoxins formed in an animal feed product during storage is included. In various embodiments, an animal feed preservative or supplement is included. Other embodiments are also included herein.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: February 5, 2019
    Assignee: Hawkins, Inc.
    Inventors: Theodore R. Stern, Stephen G. Campano, Gary Carl Larson
  • Patent number: 10168125
    Abstract: A composition for deterring intruders includes propionic acid, ammonia and water. A content of water in the composition is at least approximately 60% by weight. A system for spraying a composition comprises a nozzle configured to spray the composition in an area inside a building. The composition comprises propionic acid, ammonia and water. A content of water in the composition is at least approximately 60% by weight.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: January 1, 2019
    Assignee: CROTEGA, LLC
    Inventors: Jody Allen Crowe, Oliver D. Nichols
  • Patent number: 10154974
    Abstract: The present disclosure provides methods for treating or preventing malaria by administration of abscisic acid, analogs or pharmaceutical salts thereof to a mammalian subject infected with or at risk of exposure to Plasmodium. In some aspects, the therapeutic and prophylactic regimens of the present disclosure are effective in reducing parasitemia and gametocytemia in a mammalian subject and/or reducing transmission of Plasmodium by a mosquito vector.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: December 18, 2018
    Assignee: The Regents Of The University Of California
    Inventors: Shirley Luckhart, Elizabeth K. K. Glennon
  • Patent number: 10149610
    Abstract: Systems and methods to improve the detection and classification of inflammation in the eye are presented. The inflammatory markers in image data can be graded by comparing identified and extracted characteristics from the images with characteristics derived from a set of images of eyes from a general population of subjects. The image data can be divided into sub-regions for analysis to better isolate the true inflammatory markers from the impacts of cataracts or other opacities. In another embodiment, the location of an imaging beam can be controlled to minimize the impact of lens opacities from the collected data used to analyze the inflammation state of an eye.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: December 11, 2018
    Assignee: CARL ZEISS MEDITEC, INC.
    Inventors: Harihar Narasimha-Iyer, Mary K. Durbin
  • Patent number: 10143671
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: December 4, 2018
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 10130598
    Abstract: The present disclosure relates to the discovery that compounds of the invention, particularly 3-bromopyruvate and related compounds, can be safely administered at concentrations effective for the treatment of cancer when formulated with an acidity of greater than or equal to pH of 2 and less than or equal to a pH of 6. Disclosed herein are novel and improved methods and compositions for the treatment of cancer using 3-halopyruvate and related compounds.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: November 20, 2018
    Assignee: The Johns Hopkins University
    Inventors: Jean-Francois Geschwind, Mustafa Vali
  • Patent number: 10130646
    Abstract: A terminally sterilized aqueous calcium gluconate solution comprising 1 to 15 wt. % calcium gluconate and from 1 to 19 wt. parts of calcium saccharate per 100 wt. parts of calcium gluconate packaged in a flexible plastic container with the remainder water.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: November 20, 2018
    Assignee: HQ SPECIALTY PHARMA CORPORATION
    Inventor: Joseph Pizza
  • Patent number: 10130689
    Abstract: The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: November 20, 2018
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventor: John L. Gainer
  • Patent number: 10111849
    Abstract: Methods and compositions for treating or preventing, the occurrence of senile dementia of the Alzheimer's type, or other conditions arising from reduced neuronal metabolism and leading to lessened cognitive function are described. In a preferred embodiment the administration of triglycerides or fatty acids with chain lengths between 5 and 12, to said patient at a level to produce an improvement in cognitive ability.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: October 30, 2018
    Assignee: Accera, Inc.
    Inventor: Samuel T. Henderson
  • Patent number: 10085939
    Abstract: Stable non-alcoholic transdermal hydrogel of dexibuprofen was prepared by using a simple manufacturing process, and the experimental trials showed that the pH modifying agent, antioxidant and water miscible solvent are the essential excipients to obtain stable non-alcoholic transdermal hydrogel of dexibuprofen. The dexibuprofen hydrogel prepared using carbopol as a gelling polymer produced an opaque gel, whereas hydrogel prepared using hyroxypropyl methylcellulose (HPMC) as a gelling polymer produced a transparent gel. There was no significant changes observed with respect to physical description, pH, assay and particularly to the related substance values when the hydrogels were subjected to the stability study at accelerated condition (40° C./75% RH) for 3 months in laminated tubes.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: October 2, 2018
    Assignee: Strides Shasun Limited
    Inventors: Jeffrey Stuart Bergman, Sampathkumar Devarajan, Selvakumar Ramalingam, Anandsenthil Vel Palanisamy
  • Patent number: 10080729
    Abstract: The present invention relates to intervertebral misalignment, such as scoliosis, spondylolisthesis, vertebral subluxation and vertebral fractures. A composition for use in the treatment of intervertebral misalignment is provided. The composition comprises lactic acid, or a pharmaceutically acceptable salt thereof. The composition is administered into a disc space comprising the nucleus pulposus of an intervertebral disc.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: September 25, 2018
    Assignee: STAYBLE THERAPEUTICS AB
    Inventor: Kjell Olmarker
  • Patent number: 10077415
    Abstract: The present invention relates to novel combined laundry detergent, bleach, and antimicrobial composition incorporating novel sulfoperoxycarboxylic acid compounds, and methods for making and using them. The sulfoperoxycarboxylic compounds used in compositions of the invention are storage stable, water soluble and have low to no odor. Compositions of the invention may be in the form of a liquid, a solid, or a gel. The sulfoperoxycarboxylic compounds useful in preparing compositions of the present invention can be formed from non-petroleum based renewable materials.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 18, 2018
    Assignee: Ecolab USA Inc.
    Inventors: David W. Gohl, Robert D. P. Hei, Thomas Merz, Peter Jens Forth, Matthias Kreysel, David D. McSherry, Junzhong Li, Jonathan P. Fast
  • Patent number: 10064811
    Abstract: The present disclosure relates to methods of retarding hair loss or facilitating hair growth and/or regrowth. More specifically, the present disclosure relates to methods of using the disclosed compositions to increase the rate of terminal hair growth and/or regrowth in a mammal.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: September 4, 2018
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Longsheng Hu, Virginia Streusand Goldman, Josephine A. Minerva, Susan Wendling
  • Patent number: 10016378
    Abstract: Methods are provided for preventing, inhibiting, or treating intimal hyperplasia in a patient who has undergone a coronary bypass procedure that include providing a solution comprising DCA added to water; and administering the solution orally to a patient to prevent, inhibit, or treat intimal hyperplasia.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: July 10, 2018
    Inventors: Tobias Deuse, Sonja Schrepfer
  • Patent number: 10004230
    Abstract: Methods for the generation of non-equilibrium solutions of peroxyacetic acid are disclosed. These methods comprise introducing triacetin and aqueous hydrogen peroxide to water, mixing, and then adding an aqueous source of an alkali metal or earth alkali metal hydroxide. Triacetin is converted rapidly and with a high conversion rate into peracetic acid. These methods produce solutions with a high level of peracetic acid.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: June 26, 2018
    Assignee: Enviro Tech Chemical Services, Inc.
    Inventors: Michael S. Harvey, Jonathan N. Howarth
  • Patent number: 10001493
    Abstract: There is provided protein biomarkers and methods for their use in diagnosing and treating Inflammatory Bowel Disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) as well as methods for assessing the severity of the diseases.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: June 19, 2018
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Daniel Figeys, Alain Stintzi, David R. Mack, Cheng-Kang Chiang, Amanda Elizabeth Starr
  • Patent number: 9975917
    Abstract: A pentacyclic triterpenoidal derivative can include 3,11-dioxo-24(phenyl)-urs-12-en-24-one (4), 24-norurs-12-en-24(phenyl)-3,11-dione (5), 3,11-dioxo-24(Phenyl)-urs-1,12-diene-24-one (6), or 24-nor-urs-1,12-diene-24(phenyl)-3,11-dione (7). The pentacyclic triterpenoidal derivative demonstrates highly potent 5-lipoxygenase inhibition activity.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: May 22, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Abd El-Galil E. Amr, Mohamed A. Al-Omar, Ahmed M. Naglah
  • Patent number: 9962324
    Abstract: A composition including a buffered lactic acid having a pH within the range of from 3.0 to 6.5 is disclosed. The composition is a lubricant composition and has a water activity of from 0.03 to 0.60. The friction between the absorbent product and the skin/mucous membrane of the user is reduced when in contact with the skin or mucous membrane of the user. An additional advantage is that the composition has a pH in the acidic range which is close to the pH of the skin and/or mucous membrane.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: May 8, 2018
    Assignee: SCA HYGIENE PRODUCTS AB
    Inventors: Ulrika Husmark, Ulla Forsgren Brusk, Chatrine Stridfeldt
  • Patent number: 9936695
    Abstract: Compositions and methods for the disinfection of surfaces are provided. The compositions include an alcohol and a peracid. The disinfectant composition is characterized by a pH of no more than about 5. Broad spectrum efficacy is achieved, and synergistic activity is exhibited against bacterial and fungal spores, including Clostridium difficile spores. The compositions and methods are also useful against conformationally altered prions, bacteria, fungi, and viruses.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: April 10, 2018
    Assignee: GOJO Industries, Inc.
    Inventors: James Edmund Bingham, Christopher M. Fricker, Michael J. Dolan
  • Patent number: 9913859
    Abstract: An improved aqueous teat dip comprising iodine and chlorhexidine in an aqueous solution.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 13, 2018
    Assignee: Webco Chemical Corporation
    Inventor: Michael J. Loosemore
  • Patent number: 9877483
    Abstract: The present invention provides methods for producing a non ?-keto peracid that has lower toxicity and lower corrosivity. The present embodiments also provide methods and compositions for reducing microbes on a surface, methods, and compositions for preventing and reducing infectious vegetative bacteria on a substrate, and methods and compositions for treating a wound. In particular, compositions of the invention provide for a mixture of an ?-keto peracid and a non ?-keto peracid that works synergistically to reduce microbes on a surface, to prevent vegetative bacteria on a surface and to heal a wound in animals or humans.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: January 30, 2018
    Assignee: Armis Biopharma, Inc.
    Inventors: Edwin D. Neas, John D. Skinner
  • Patent number: 9822104
    Abstract: Disclosed are taxifolin derivative with superior antioxidant effect, a method of synthesizing the same and a cosmetic composition containing the same. In accordance with the method, taxifolin derivatives having higher antioxidant activity than taxifolin can be synthesized using lipoic acid. As such, a novel taxifolin derivative synthesized according to the present invention can exhibit anti-aging effects when used for cosmetics and the like.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: November 21, 2017
    Assignee: Yeomyung Biochem Co., Ltd.
    Inventors: Jae Duk Lee, Hyun Jin An, Da Hye Park, Yong Sub Yi, Yong Hwa Lee
  • Patent number: 9814796
    Abstract: Methods for killing spores include contacting the spores with an aqueous solution containing performic acid. The contacting occurs at a temperature of less than or equal to about 35° C. for a period of time of less than or equal to about 15 seconds, and the contacting effects at least a 4 log reduction in a number of spores capable of reproduction, metabolism, and/or growth.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: November 14, 2017
    Assignees: PERFORMANCE PACKAGING OF NEVADA, LLC
    Inventor: Joseph Dunn
  • Patent number: 9782372
    Abstract: There is provided pharmaceutical compositions suitable for topical application to the nail for the treatment of nail diseases such as onychomycosis, comprising a urea-based component, a diol component, such as propylene glycol, an organic acid component, such as lactic acid, and a triol component, such a glycerol. There is further provided methods of improving the storage stability of a pharmaceutical composition suitable for topical application to the skin and/or nails comprising such urea-based components, diol components, organic acid components, and, optionally, an aqueous base, which method comprises adding a triol component, such a glycerol, to that composition prior to said storage.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: October 10, 2017
    Assignee: Moberg Pharma AB
    Inventors: Ewa Karlsson, Sahar Feizollahi Ashkar, Peter Kaufmann
  • Patent number: 9770424
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: September 26, 2017
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Patent number: 9757347
    Abstract: An ingestion method of creatine composition, taking orally the creatine composition with beverage, characterized in that, the creatine composition is taken orally by preparing creatine composition aqueous solution with dissolving the creatine composition over one minute into water heating at 80-100° C. and by mixing the creatine composition aqueous solution with the beverage having ordinary or cool temperature.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: September 12, 2017
    Inventors: Hirohisa Nishizawa, Haruhiko Sueoka
  • Patent number: 9737487
    Abstract: The invention provides compositions comprising cyclodextrins encapsulating a selective ATP inhibitor, as well as uses thereof.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: August 22, 2017
    Assignee: The Johns Hopkins University
    Inventors: Jean-Francois Geschwind, Shanmugasundaram Ganapathy-Kanniappan, Surojit Sur, Bert Vogelstein, Kenneth W. Kinzler
  • Patent number: 9737072
    Abstract: Methods for the generation of non-equilibrium solutions of peroxyacetic acid are disclosed. These methods comprise introducing triacetin and aqueous hydrogen peroxide to water, mixing, and then adding an aqueous source of an alkali metal or earth alkali metal hydroxide. Triacetin is converted rapidly and with a high conversion rate into peracetic acid. These methods produce solutions with a high level of peracetic acid.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: August 22, 2017
    Assignee: Enviro Tech Chemical Services, Inc.
    Inventors: Michael S. Harvey, Jonathan N. Howarth
  • Patent number: 9706790
    Abstract: The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: July 18, 2017
    Assignee: CHROMOCELL CORPORATION
    Inventors: Francis Xavier Brennan, William P. Jones, Jane V. Leland, David Hayashi
  • Patent number: 9708256
    Abstract: The present invention relates to apparatus and methods for making a peroxycarboxylic acid. The apparatus includes a reaction catalyst and a guard column for pretreating one or more reagents, which can increase the life, activity, and/or safety of the reaction catalyst. The peroxycarboxylic acid compositions made by the method and apparatus can include one or more peroxycarboxylic acids.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: July 18, 2017
    Assignee: Ecolab USA Inc.
    Inventors: David D. McSherry, Richard Staub, Dan N. Tallman, Junzhong Li, Keith D. Lokkesmoe
  • Patent number: 9693935
    Abstract: A Personal care 100% plant derived, biodegradable solid granules that sustain beneficial essential oils, and or plant/herbal extracts and emulsify in hot water to create an emulsified therapeutic solution is disclosed. This invention improves over existing liquids in that it's solid granule form is completely plant derived and biodegradable and can sustain essential oils and antioxidants without the requirement of chemical preservatives, and can be packaged in eco-friendly, compostable paper. It improves over existing solid forms in that it is a 100% water soluble granule that emulsifies easily in hot water to form an easy to use liquid product.
    Type: Grant
    Filed: January 13, 2013
    Date of Patent: July 4, 2017
    Inventor: Sarah McCoy
  • Patent number: 9682056
    Abstract: A description and explanation is provided of the use of oleacein, especially this obtained from Ligustrum vulgare L., in the manufacturing of a preparation for the treatment and prevention of diseases that are consequences of the atherosclerotic plaque degradation. Such diseases include in particular those selected from the following group: ischemic brain stroke, heart attack and ischemic heart disease.
    Type: Grant
    Filed: July 13, 2013
    Date of Patent: June 20, 2017
    Assignee: Warszawski Uniwersytet Medyczny
    Inventors: Monika Ewa Czerwinska, Anna Karolina Kiss, Marek Aleksy Naruszewicz, Agnieszka Filipek
  • Patent number: 9622963
    Abstract: A method for stimulating hair growth includes providing a topical composition including a purified oil extract from Melaleuca alternifolia, also known as tea tree. The method may further include applying the topical composition to the skin surrounding the follicles of the human hair at least once a day. A method for preventing the loss of human hair includes providing a topical composition including a purified oil extract from Melaleuca alternifolia, also known as tea tree. The method may further include applying the topical composition to the skin surrounding the follicles of the human hair at least once a day.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: April 18, 2017
    Assignee: NNC Blending LLC
    Inventor: Steven Constantino
  • Patent number: 9603823
    Abstract: Methods and compositions for treating or preventing, the occurrence of senile dementia of the Alzheimer's type, or other conditions arising from reduced neuronal metabolism and leading to lessened cognitive function are described. In a preferred embodiment the administration of triglycerides or fatty acids with chain lengths between 5 and 12, to said patient at a level to produce an improvement in cognitive ability.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: March 28, 2017
    Assignee: Accera, Inc.
    Inventor: Samuel T. Henderson
  • Patent number: 9592212
    Abstract: The present invention provides a therapeutic treatment for a neurodegenerative disease with a pan-PPAR agonist, such as bezafibrate. In particular, the present invention provides that pan-PPAR agonists enhance PPAR related responses in both the central nervous system and peripheral tissues in Huntington's Disease (HD) and tauopathy. Therapeutic compositions comprising one or more pan-PPAR agonist(s), and kit thereof, for treating a neurodegenerative disease or disorder are also provided.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: March 14, 2017
    Assignee: Cornell University
    Inventor: Flint Beal
  • Patent number: 9578879
    Abstract: Compositions and methods for the disinfection of surfaces are provided. The compositions include an alcohol and a peracid. The disinfectant composition is characterized by a pH of no more than about 5. Broad spectrum efficacy is achieved, and synergistic activity is exhibited against bacterial and fungal spores, including Clostridium difficile spores. The compositions and methods are also useful against conformationally altered prions, bacteria, fungi, and viruses.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: February 28, 2017
    Assignee: GOJO INDUSTRIES, INC.
    Inventors: James Edmund Bingham, Christopher M. Fricker, Michael J. Dolan
  • Patent number: 9560874
    Abstract: Described is a method of sanitizing animal carcasses using aqueous streams having an antimicrobial composition added to the stream. Preferably, the antimicrobial composition includes a mixture of one or more carboxylic acids having up to 18 carbon atoms and one or more peroxycarboxylic acids having up to 12 carbon atoms, preferably a mixture of a C2-C4 peroxycarboxylic acid and a C8-C12 peroxycarboxylic acid. Also described is a novel antimicrobial composition adapted for sanitizing animal carcasses containing a mixture of one or more C2-C4 peroxycarboxylic acids and one or more C8-C12 peroxycarboxylic acids and an alpha-hydroxy mono- or dicarboxylic acid.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: February 7, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Timothy A. Gutzmann, Brian J. Anderson, Pamela J. Reed, Bruce R. Cords, Lawrence A. Grab, Edward H. Richardson
  • Patent number: 9555017
    Abstract: Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: January 31, 2017
    Assignee: Jazz Pharmaceuticals Ireland Limited
    Inventors: Clark P. Allphin, Michael DesJardin
  • Patent number: 9521859
    Abstract: Disclosed are substantially clear nutritional liquids comprising protein and calcium HMB wherein soluble protein represents from about 65% to 100% by weight of total protein. The liquids have a pH of from about 2.8 to about 4.6 and may be manufactured as a hot fill product. The substantially clear nutritional liquids may also have a weight ratio of calcium HMB to soluble calcium of from 4.5:1 to 7.3:1. In some embodiments, the substantially clear nutritional liquids are substantially free of fat, and may optionally include isomaltulose and/or beta alanine.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: December 20, 2016
    Inventors: Normanella T. DeWille, Kelley J. Lowe, Terrence B. Mazer, Paul W. Johns
  • Patent number: 9498433
    Abstract: An edible animal medicine container for delivering medicine or other ingestible material, contained therein, to an animal, includes first and second edible housing shells. The first shell includes a first peripheral ledge, surrounding a first central hollow, and a first interlocking feature extending therefrom. The second shell includes a second peripheral ledge, surrounding a second central hollow, and a second interlocking feature extending into, and at least partially defined by, the second peripheral ledge. The second shell is positionable relative to, and connectable to, the first shell to define an interior in which the ingestible material may be disposed. In such connected state the first interlocking feature is seated and frictionally held within the second interlocking feature of the second edible housing shell so as to retain the first and second shells together and thereby retain the ingestible material within the interior until ingested by an animal.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: November 22, 2016
    Assignee: Make Ideas, LLC
    Inventors: Keith Alan Mullin, William Bradley Allen
  • Patent number: 9486465
    Abstract: Provided are an attractant for bone marrow stem cells containing at least one of cinnamtannin B1 and pentagalloylglucose, and a method for attracting bone marrow stem cells in which bone marrow stem cells are attracted by the attractant.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: November 8, 2016
    Assignees: Pias Corporation, Osaka University
    Inventors: Tadashi Furumoto, Koichi Nakaoji, Kazuhiko Hamada, Noriyasu Ozawa, Yuta Inami, Misaki Toyoshima, Kosuke Fujita, Akito Maeda, Yasufumi Kaneda, Katsuto Tamai
  • Patent number: 9480666
    Abstract: Methods are provided for preventing, inhibiting, or treating intimal hyperplasia in a patient who has undergone a coronary bypass procedure that include providing a solution comprising DCA added to water; and administering the solution orally to a patient to prevent, inhibit, or treat intimal hyperplasia.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: November 1, 2016
    Inventors: Tobias Deuse, Sonja Schrepfer
  • Patent number: 9474708
    Abstract: The present invention provides for a formulation comprising: at least one hydrophilic polymer, at least one desquamatory agent and alpha hydroxyl acid.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: October 25, 2016
    Inventor: Julius Zecchino
  • Patent number: 9456589
    Abstract: Compounds for repelling elasmobranch having an aldehyde or derivative, a carboxylic acid a derivative, a ketone or a derivative thereof, a di-ketone or a derivative thereof, a pyridine or derivative thereof, or an antipyrine or a derivative thereof and methods of use thereof.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: October 4, 2016
    Inventor: Eric Matthew Stroud
  • Patent number: 9427437
    Abstract: This invention provides compositions and methods of inhibiting, suppressing, or treating a tendinous or musculoskeletal soft tissue injury. The invention further provides a method of ameliorating symptoms associated with a tendinous or musculoskeletal soft tissue injury. Additionally, the invention provides methods for evaluating the risk of developing a tendinous or musculoskeletal soft tissue injury.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: August 30, 2016
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Joseph A. Abboud, Louis J. Soslowsky
  • Patent number: 9399026
    Abstract: Disclosed herein are methods and compositions for alleviating side effects of statin administration, such as myopathic or myalgic side effects, short-term memory loss, abnormal liver function, glucose intolerance, hyperglycemia, increased risk for diabetes, or cumulative trauma disorder, comprising administration of ?-hydroxy ?-methylbutyrate (HMB) to an individual taking a statin. Also disclosed are methods and compositions for alleviating acute rhabdomyolysis comprising administration of HMB. The disclosure further provides uses of HMB in combination with a statin to alleviate side effects of statin administration.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: July 26, 2016
    Inventor: Roland W. Winterfield