Carbon To Carbon Unsaturation Patents (Class 514/703)
  • Patent number: 10639252
    Abstract: The present invention provides a skin peel composition including a plurality of substances, such as lactic acid, salicylic acid, and resorcinol and, additionally a post-inflammatory hyper pigmentation reducing substance such as a retinol (vitamin A) or retinol derivative. Skin is first prepared using an alcohol preparation followed by a combinations of acids and, lastly, a retinol or retinol derivatives. Other agents such as ascorbic acid (vitamin C) and vitamin E can be added as needed. Application of the skin peel composition may be either topically in the form of a cream or gel, and may further be injected subcutaneously into the skin to achieve deeper penetration of the composition within the skin layers of the area to be treated.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: May 5, 2020
    Assignee: Allergan, Inc.
    Inventors: Lora Colvan, Rahul Mehta, Sujatha Sonti
  • Patent number: 9629911
    Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: April 25, 2017
    Assignee: The Regents of the University of California
    Inventors: Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
  • Patent number: 9554990
    Abstract: A method is provided to promote secretion of cholecystokinin (CCK) by administering an active component. The active component includes acrylic acid and/or an unsaturated aldehyde having a main chain of 4 to 12 carbon atoms having a double bond in at least position 2 or 4, where the main chain has 4 to 9 carbon atoms when there is a double bond in only position 2, and the main chain has 9 to 12 carbon atoms when there is a double bond in only position 4. The cholecystokinin secretion-promoting composition can be used as an appetite suppressant. By adding this cholecystokinin secretion-promoting composition to food, appetite-suppressing food products can be provided.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: January 31, 2017
    Assignee: J-Oil Mills, Inc.
    Inventors: Hiroshi Hara, Tohru Hira, Chigusa Nishiyama, Noriko Tokura, Takatoshi Yamashita, Jun Imagi
  • Patent number: 9532717
    Abstract: A method for diagnosing the presence of a vulvovaginal disorder is provided. The method uses a source of cross-polarized light to detect subsurface irritation in the vulvovaginal area. The presence of subsurface irritation is then used to diagnose the presence of a vulvovaginal disorder.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: January 3, 2017
    Assignee: The Procter & Gamble Company
    Inventor: Miranda Aref Farage
  • Patent number: 9427415
    Abstract: Compounds and methods for modifying sensory perception associated with transient sensory receptors TRPA1, TRPV1, and TRPA1V1. A method for screening compounds for modulation of TRPA1, TRPV1, and/or TRPA1V1. Compositions comprising TRPA1V1 agonists or antagonists, for modifying sensory perception of the compositions.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: August 30, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Koti Tatachar Sreekrishna, Yakang Lin
  • Patent number: 9089141
    Abstract: The natural insect repellent BBX2 is a composition of refined oils such as Citronella, Cedar, Mineral, Castor, and Oleic Acid with Diatomaceous Earth to repel insects from landing on and remaining on human skin. It can be made in many different forms such as liquid, lotion, spray, paste, cream and can be a part of articles such as animal collars, garbage bags, planting material, and of course fabrics for clothing, tents, and anything that a person would use or wear.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: July 28, 2015
    Inventor: John James McIntyre
  • Patent number: 9078852
    Abstract: The present invention is directed to methods of treating a patient for a disease or condition associated with adipogenesis or insulin resistance by administering a retinaldehyde compound to the patient or a compound that increases endogenous retinaldehyde levels by inhibiting the enzyme retinaldehyde dehydrogenase 1.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: July 14, 2015
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Jorge Plutzky, Ouliana Ziouzenkova
  • Publication number: 20150098910
    Abstract: In certain embodiments, the present invention relates to compounds, compositions, and methods for disrupting biofilms. In some embodiments, the compounds and compositions comprise unsaturated long chain alcohols and/or aldehydes, or combinations of such compounds. In further embodiments, the present invention contains therapeutic actives to help reduce and/or eradicate the bacteria in the biofilm once the film is disrupted.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Carolyn J. Mordas, Robert J. Gambogi
  • Publication number: 20150099015
    Abstract: Methods and compositions are provided for treating neuropsychiatric disorders such as schizophrenia, depression, attention deficit disorder, mild cognitive impairment, dementia, and bipolar disorder. The methods entail administering to a patient diagnosed as having a neuropsychiatric disorder (e.g., schizophrenia, depression, attention deficit disorder, mild cognitive impairment, dementia bipolar disorder, etc.) or as at risk for a neuropsychiatric disorder a benzoic acid, benzoic acid salt, and/or benzoic acid derivative, and/or a sorbic acid, sorbic acid salt, and/or sorbic acid derivative, in combination with a neuropharmacological agent (e.g., an antipsychotic, an antidepressant, medications for attention deficit and hyperactivity disorder, cognitive impairment, or dementia, etc.) where the benzoic acid, benzoic acid salt, or benzoic acid derivative, and/or a sorbic acid, sorbic acid salt, and/or sorbic acid derivative, is in an amount sufficient to increase the efficacy of the neuropharmacological agent.
    Type: Application
    Filed: November 24, 2014
    Publication date: April 9, 2015
    Inventor: Guochuan Emil TSAI
  • Patent number: 8993637
    Abstract: The present invention relates to a new use of citral for manufacturing a medicament for treating focal segmental glomerulosclerosis (FSGS). Particularly, the present invention discloses that citral is effective in alleviating symptoms of FSGS, including reducing glomerular epithelial hyperplasia lesions (EPHLs), peri-glomerular inflammation or glomerular hyalinosis or sclerosis, and also reducing proteinuria or hematuria or lowering serum urea nitrogen level or serum creatinine level in the subject.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 31, 2015
    Assignee: National Defense Medical Center
    Inventors: Ann Chen, Kuo-Feng Hua, Shuk-Man Ka, Kuo-Ping Chao, Wen-Liang Chang, Kuo-Yuan Hwa
  • Patent number: 8962691
    Abstract: Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 24, 2015
    Assignee: University of Washington
    Inventors: Krzysztof Palczewski, David A. Saperstein
  • Publication number: 20150011649
    Abstract: The present invention provides methods of treating a human or other mammal infected with a parasitic microorganism by administering an effective amount in unit dosage form of a C8-C16-alpha, beta-unsaturated aliphatic aldehyde, such as trans-2-dodecenal, to the human or other mammal. The parasitic microorganisms may include trypanosomes, bacteria, fungi and nematodes.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 8, 2015
    Applicant: SLIPPERY ROCK UNIVERSITY FOUNDATION, INC.
    Inventors: Wayne M. FORBES, Carolyn S. STEGLICH
  • Publication number: 20140378530
    Abstract: The technology described herein is directed to methods of treating, e.g. obesity by administering retinaldehyde increasing agents.
    Type: Application
    Filed: February 1, 2013
    Publication date: December 25, 2014
    Inventors: Jorge Plutzky, Florian Kiefer
  • Publication number: 20140357709
    Abstract: (Modified) sorghum protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) sorghum protein and at least one active ingredient and to their manufacture, as well as to the (modified) sorghum protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) sorghum protein and such a composition, respectively.
    Type: Application
    Filed: August 13, 2014
    Publication date: December 4, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventor: Christian SCHAEFER
  • Publication number: 20140343167
    Abstract: The present invention relates to a new use of citral for manufacturing a medicament for treating focal segmental glomerulosclerosis (FSGS). Particularly, the present invention discloses that citral is effective in alleviating symptoms of FSGS, including reducing glomerular epithelial hyperplasia lesions (EPHLs), peri-glomerular inflammation or glomerular hyalinosis or sclerosis, and also reducing proteinuria or hematuria or lowering serum urea nitrogen level or serum creatinine level in the subject.
    Type: Application
    Filed: April 11, 2014
    Publication date: November 20, 2014
    Applicant: National Defense Medical Center
    Inventors: Ann CHEN, Kuo-Feng HUA, Shuk-Man KA, Kuo-Ping CHAO, Wen-Liang CHANG, Kuo-Yuan HWA
  • Patent number: 8877809
    Abstract: Methods of retarding formation of a lipofuscin pigment in the retina and of treating or ameliorating the effects of a disease characterized by an accumulation of a lipofuscin pigment in a retina are provided. These methods include the step of administering to a patient in need thereof a substituted C20-retinoid in an amount sufficient to reduce accumulation of a lipofuscin pigment in the retina. Further provided are methods of retarding formation of A2E and/or ATR-dimer by replacing an all-frans-retinal (ATR) substrate with a C20-D3-retinal substrate under conditions sufficient to impede the formation of A2E. Compositions for retarding formation of a lipofuscin pigment in the retina containing a substituted C20-retinoid and a pharmaceutically acceptable carrier are also provided.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: November 4, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Ilyas Washington
  • Patent number: 8865774
    Abstract: The present invention provides methods of treating a human or other mammal infected with a parasitic microorganism by administering an effective amount in unit dosage form of a C8-C16-alpha, beta-unsaturated aliphatic aldehyde, such as trans-2-dodecenal, to the human or other mammal. The parasitic microorganisms may include trypanosomes, bacteria, fungi and nematodes.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: October 21, 2014
    Assignee: Slippery Rock University Foundation
    Inventors: Wayne M. Forbes, Carolyn S. Steglich
  • Publication number: 20140302169
    Abstract: A method wherein subjects having or at risk for having hyperopia, presbyopia or astigmatism are administered a composition having an effective amount of ocular antioxidants, including specifically macular pigments, to prevent, treat, or delay the onset of age-related macular degeneration (AMD).
    Type: Application
    Filed: June 18, 2014
    Publication date: October 9, 2014
    Inventor: Richard Roberts
  • Patent number: 8853437
    Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: October 7, 2014
    Assignee: The University of Tokyo
    Inventors: Makoto Arita, Hiroyuki Arai, Yousuke Isobe, Ryo Taguchi
  • Publication number: 20140271537
    Abstract: The present invention generally relates to deuterium-enriched aldehydes, compositions comprising deuterium-enriched aldehydes, and methods for slowing the rate of aldehyde autoxidation. In one aspect, the present invention provides a composition comprising a compound of structure 1: wherein: there are at least 6×1018 molecules of the aldehyde and Rx is hydrogen, wherein the deuterium isotope in Rx is in an amount greater than 0.10 percent of the hydrogen atoms present in Rx.
    Type: Application
    Filed: March 15, 2014
    Publication date: September 18, 2014
    Inventor: Anthony W. Czarnik
  • Publication number: 20140271879
    Abstract: Fine dry particulate retinoid compositions suitable for use in topical formulations, as well as methods of making the same, are provided. In the dry particulate retinoid compositions, the retinoid active agent is associated with the particles, e.g., via entrapment in the pores of the particles and/or ionic binding and/or non-covalent binding to the surface of the particles and/or loosely associated with the particles. Also provided are topical formulations which include the dry particulate retinoid compositions of the invention, and methods of using the same.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Zahra Mansouri, Xin Chen, Rodica-Tatiana Canelide
  • Patent number: 8834908
    Abstract: A pest-combating composition including sodium lauryl sulfate and one or more of C6-12 fatty acids, preferably lauric and/or capric and/or caprylic acid, soy methyl ester, and 2-undecanone, and methods of combating pests utilizing same, are disclosed. The compositions can include a carrier oil such as silicon oil, soy methyl ester, or a vegetable oil, and can be in the form of an emulsion. The composition may be constituted as a spray composition, an aerosol, a lotion, a paste, or another compositional form. Pests that may be usefully combated with such composition include flying insects, including flies, mosquitoes, and wasps, ants, including arthropods such as fire ants, ticks, fleas, cockroaches, silver fish, thrips, gnats, aphids, Japanese beetles, and agricultural and horticultural arthropods and insects including beetles (potato and bean), flea beetles, fleahoppers, squash bugs, slugs, leaf hoppers, harlequin bugs, milk weed bugs, spiders, mites, lice, rodents, and deer.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: September 16, 2014
    Assignee: HOMS, LLC
    Inventor: Allen Jones
  • Publication number: 20140256795
    Abstract: Disclosed herein is a method of promoting sustained survival, sustained regeneration, in a lesioned mature neuron, sustained compensatory outgrowth in a neuron, or combinations thereof. The method comprises contacting the lesioned mature neuron with an effective amount of an inhibitor of PTEN and an effective amount of an inhibitor of SOCS3 to thereby promote survival and/or regeneration and/or compensatory outgrowth of the neuron. Therapeutic methods of treatment of a subject with a neuronal lesion by administration of a therapeutically effective amount of an inhibitor of PTEN and a therapeutically effective amount of an inhibitor of SOCS3, are also disclosed, as are pharmaceutical compositions and devices for use in the methods.
    Type: Application
    Filed: November 1, 2012
    Publication date: September 11, 2014
    Inventors: Zhigang He, Duo Jin, Fang Su
  • Publication number: 20140256826
    Abstract: The present document describes a method of reducing a microbial presence on at least one part of a subject by topically contacting the subject's part with an antimicrobial formulation comprising: a) at least one antimicrobial isolated or synthetic phenolic compound of natural origin; b) at least one surfactant sufficient to form a solution or dispersion of said phenolic compound in an aqueous carrier; c) a solvent for dissolving said phenolic compound; and d) a sufficient aqueous carrier quantity to make 100% (w/w).
    Type: Application
    Filed: March 8, 2013
    Publication date: September 11, 2014
    Applicant: Laboratoire M2
    Inventors: Gaetan LEMIRE, Ulysse DESRANLEAU DANDURAND, Sylvain QUESSY, Ann LETELLIER
  • Publication number: 20140256825
    Abstract: Compositions (feeding deterrent/repellent for Halyomorpha halys) containing at least two compounds selected from tridecane, E-2-decenal, isolongifolanone, isolongifolenone, and at least one isolongifolenone analog having the following formula: wherein R1 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid and R2 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid; optionally there is a double bond between carbons 5 and 6 and R2 is hydrogen; and optionally a carrier or carrier material. Also methods for deterring feeding/repelling Halyomorpha halys involving treating an object or area with a Halyomorpha halys deterring feeding/repelling effective amount of at least one compound selected from the above compounds.
    Type: Application
    Filed: February 7, 2013
    Publication date: September 11, 2014
    Applicant: The United States of America, as represented by the Secretary of Agriculture
    Inventor: The United States of America, as represented by the Secretary of Agriculture
  • Publication number: 20140170198
    Abstract: The present invention relates to compositions comprising terpenes which are particularly suitable for treating plant infections, to methods of making such compositions, and to methods of using them. The present invention also relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions; such compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions in the medical, veterinary and agricultural fields. In particular, the terpenes disclosed are thymol, eugenol, geraniol, citral and L-carvone.
    Type: Application
    Filed: February 25, 2014
    Publication date: June 19, 2014
    Applicant: Eden Research PLC
    Inventors: Lanny Franklin, Gary Ostroff
  • Patent number: 8741965
    Abstract: A device or collar having a matrix into which an interomone is incorporated in an amount from between about 0.001% and about 5% by weight of the device is described for the modification of undesirable or harmful stress-related behaviors or other behaviors of physiology in a variety of vertebrate species over an extended period of time, as well as methods of using the device to modify behaviors of a variety of vertebrate species over an extended period of time.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 3, 2014
    Assignee: Sergeant's Pet Care Products, Inc.
    Inventors: Larry Nouvel, John McGlone
  • Patent number: 8741964
    Abstract: The present invention relates to a method for preventing or treating dyslipidemia or fatty liver, comprising: administering to a mammalian subject in need thereof a therapeutically effective amount of a composition comprising nonenal. The present composition containing nonenal as an active ingredient is very effective in preventing or treating obesity, diabetes, dyslipidemia, fatty liver or insulin resistance syndrome (preferably, dyslipidemia or fatty liver, more preferably hyperlipidemia or fatty liver). The composition of the present invention useful as pharmaceuticals compositions or functional food compositions has therapeutic efficacies for obesity, diabetes, hyperlipidemia or fatty liver, and also induces significant decrease in fasting glucose level and blood insulin level to improve type 2 diabetes, insulin resistance and related metabolic disorders.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: June 3, 2014
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventor: Tae Sun Park
  • Publication number: 20140121646
    Abstract: Methods and devices for preventing nutrient absorption in the small intestine wherein a medical device is passed through the esophagus, and positioned in the small intestine to treat the interior mucosal surface of the small intestine, causing a reduced capacity for nutrient absorption in the treated segment. In one embodiment, the device contains an element that isolates the segment to be treated and allows for the delivery and removal of treatment agents and neutralizing agents.
    Type: Application
    Filed: October 29, 2012
    Publication date: May 1, 2014
    Inventors: David Lodin, Kemal Schankereli, Howard Lederer
  • Publication number: 20140105952
    Abstract: Compositions and methods for controlling and/or repelling bedbugs are provided. The compositions comprise one or more compounds having bedbug repellant activity. Such compounds may be, for example, naturally occurring semiochemicals or structural or functional analogs of naturally occurring semiochemicals. Exemplary compounds are compounds of general formula (I).
    Type: Application
    Filed: March 29, 2012
    Publication date: April 17, 2014
    Applicant: SemiosBIO Technologies Inc.
    Inventor: Michael Gilbert
  • Patent number: 8614253
    Abstract: Compounds which directly inhibit IRE-1? activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: December 24, 2013
    Assignee: MannKind Corporation
    Inventors: John Bruce Patterson, David Gregory Lonergan, Gary A. Flynn, Qingping Zeng, Peter V. Pallai
  • Publication number: 20130331323
    Abstract: A compound for controlling blood glucose level has a structure shown in Formula I: wherein R5-R8 are as defined herein. A method for controlling blood glucose level includes administering to a subject in need thereof a compound of Formula I. The method further includes administering to the subject a GLP-1 receptor ligand. The compound and the GLP-1 receptor ligand may be administered together. The compound may be Galanal A or Galanal B. The GLP-1 receptor ligand may be GLP-1 or exendin-4.
    Type: Application
    Filed: June 6, 2013
    Publication date: December 12, 2013
    Applicant: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Hui-Ling Chen, Yu-Yuan Wu, Jiann-Jyh Huang, Shoei-Sheng Lee, K-Lim King
  • Publication number: 20130317098
    Abstract: (Modified) sorghum protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) sorghum protein and at least one active ingredient and to their manufacture, as well as to the (modified) sorghum protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) sorghum protein and such a composition, respectively.
    Type: Application
    Filed: November 10, 2011
    Publication date: November 28, 2013
    Inventor: Christian Schaefer
  • Publication number: 20130310463
    Abstract: Provided is a material safely promoting the production of estrogen in a living body. The invention relates to use of a compound represented by the following formula (I) or a solvate thereof for producing an aromatase activator. The invention relates to an aromatase activation method comprising administering a compound represented by the following formula (I) or a solvate thereof (wherein the dashed line indicates that the bond may be a double bond, provided that a and b in the formula (I) do not simultaneously represent a double bond).
    Type: Application
    Filed: January 27, 2012
    Publication date: November 21, 2013
    Applicant: KAO CORPORATION
    Inventors: Susumu Ichinose, Shingo Kakuo
  • Patent number: 8586635
    Abstract: The present invention is related to an antifungal composition for the inhibition of wood decay caused by wood rot fungi. The invention further comprises a method for the inhibition of wood decay with gallates.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: November 19, 2013
    Assignee: National Taiwan University
    Inventors: Shang-Tzen Chang, Fu-Lan Hsu, Hui-Ting Chang, Tsair-Bor Yen
  • Publication number: 20130261191
    Abstract: Essential oil compounds, such as p-cymene, thymol, salicylaldehyde, tea tree oil, peppermint oil, cuminaldehyde, cinnamic acid, cinnamic alcohol, farnesal and farnesylacetone, especially 2-decenal and nerolidol when added to feed or drinking water to combat histomonas, a single cell protozoan organism that is an intestinal parasite infecting both vertebrates and invertebrates.
    Type: Application
    Filed: May 16, 2013
    Publication date: October 3, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Marco FREHNER, Riccardo Losa, Didier Archain
  • Publication number: 20130236610
    Abstract: This application relates to compositions and methods for inhibiting the growth of potato pathogens preventing disease during post-harvest storage and processing conditions.
    Type: Application
    Filed: August 15, 2011
    Publication date: September 12, 2013
    Applicant: UNIVERSITY OF IDAHO
    Inventor: Phillip Wharton
  • Publication number: 20130210775
    Abstract: Provided is an agent for reducing odors of pyrazine derivatives based on an olfactory receptor antagonism. The agent for reducing odors of pyrazine derivatives includes at least one antagonist of olfactory receptor OR5K1 as an active ingredient.
    Type: Application
    Filed: December 4, 2012
    Publication date: August 15, 2013
    Applicant: Kao Corporation
    Inventor: Kao Corporation
  • Publication number: 20130210927
    Abstract: A device or collar having a matrix into which an interomone is incorporated in an amount from between about 0.001% and about 5% by weight of the device is described for the modification of undesirable or harmful stress-related behaviors or other behaviors of physiology in a variety of vertebrate species over an extended period of time, as well as methods of using the device to modify behaviors of a variety of vertebrate species over an extended period of time.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Applicant: Sergeant's Pet Care Products, Inc.
    Inventor: Sergeant's Pet Care Products, Inc.
  • Publication number: 20130196950
    Abstract: Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
    Type: Application
    Filed: December 7, 2012
    Publication date: August 1, 2013
    Applicant: University Of Washington
    Inventor: University of Washingon
  • Patent number: 8481063
    Abstract: The present invention relates to a hydrated compound of an unsaturated monoterpenoid as well as its use as insect repellent.
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: July 9, 2013
    Assignee: Fulltec AG
    Inventor: Franz Bencsits
  • Publication number: 20130165453
    Abstract: The invention provides for the use of protein kinase activators or boosters of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) or other neurotrophic factors to treat stroke. Specifically, the present invention provides methods of treating stroke comprising the steps of identifying a subject having suffered a stroke and administering to said subject an amount of a pharmaceutical composition comprising a protein kinase C (PKC) activator or 4-methylcatechol acetic acid (MCBA) and a pharmaceutically acceptable carrier effective to treat at least one symptom of stroke.
    Type: Application
    Filed: July 19, 2012
    Publication date: June 27, 2013
    Inventors: Miao-Kun Sun, Daniel L. Alkon
  • Publication number: 20130149362
    Abstract: Treatment products and methods are disclosed. An example treatment product may be used for treating skin disorders by stimulating the dermis and epidermis skin layers. The example treatment product may have a composition of retinal in the amount of at least 0.15% by weight, and a liposome surrounding the retinal.
    Type: Application
    Filed: February 4, 2013
    Publication date: June 13, 2013
    Inventor: Benjamin Johnson
  • Publication number: 20130123308
    Abstract: A method for trapping, and neutralizing or killing microorganisms on a surface includes applying a barrier-forming composition that comprises an antimicrobial agent onto an inanimate surface, forming a barrier layer on the inanimate surface, in the barrier, trapping and killing microorganisms encountered on the surface and encountered from the environment after the applying step is performed. A composition for performing the method is also included. The dual-action of trapping and killing produces a barrier layer that has a powerful and long-lasting antimicrobial cidal or static activity. Compositions and methods are also included that have odor inhibiting activity and with activity to improve visual appearance of surfaces with microbial growth or discoloration.
    Type: Application
    Filed: January 4, 2013
    Publication date: May 16, 2013
    Applicant: Oasis Consumer Healthcare, LLC
    Inventor: Oasis Consumer Healthcare, LLC
  • Publication number: 20130109570
    Abstract: Fumigant compositions including hexafluoropropene or 1,1,3,3,3-pentafluoropropene, and methods of preparing such compositions, are provided herein. The fumigant compositions may be suitable for use as soil fumigant compositions and structural fumigant compositions against a variety of undesirable species such as weeds, nematodes, pathogens, animals and insects. The fumigant compositions also have low toxicity and low Global Warming Potential.
    Type: Application
    Filed: October 15, 2012
    Publication date: May 2, 2013
    Applicant: HONEYWELL INTERNATIONAL INC.
    Inventor: HONEYWELL INTERNATIONAL INC.
  • Publication number: 20130101687
    Abstract: Insecticidal compositions have at least one active agent and at least one insecticide. The active agent can include perilla oil, a component found in perilla oil, or a perillaldehyde or carvone analog. The insecticide can include a pyrethrum, pyrethrin, pyrethroid, neonicotinoid, chlofenapyr, ethiprole, sulfoxoflor, carbamate, organophosphate, or organochlorine. Methods for controlling insects include contacting an insect with an effective amount of a composition described in this specification. Modified plants that produce an active agent can be contacted with an insecticide.
    Type: Application
    Filed: July 13, 2012
    Publication date: April 25, 2013
    Inventors: Michael Dean Willis, Marie Elizabeth Saunders, Darryl Ramoutar, Joanna Maria Szymczyk, Frances Nita Krenick, Andrea Rohrbacher
  • Publication number: 20130072569
    Abstract: Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Krzysztof PALCZEWSKI, David A. SAPERSTEIN
  • Publication number: 20130072559
    Abstract: Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Krzysztof PALCZEWSKI, Matthew Batten
  • Publication number: 20130072570
    Abstract: A composition comprising an interomone is described for the modification of undesirable or harmful stress-related behaviors or other behaviors or physiology in a variety of vertebrate species, as well as methods of using the compositions in vertebrates from a species different than the species in which the interomone is a naturally occurring pheromone.
    Type: Application
    Filed: September 20, 2012
    Publication date: March 21, 2013
    Applicant: Sergeant's Pet Care Products, Inc.
    Inventor: Sergeant's Pet Care Products, Inc.
  • Publication number: 20130072568
    Abstract: Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Krzysztof Palczewski, David A. Saperstein