Natural Gum Or Resin Patents (Class 514/782)
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Patent number: 5484776Abstract: This invention relates to a process for the production of optimally stable orally administrable solution forms of medicaments containing high-molecular polysaccharides, with controlled release of drugs having beta-blocking action, this process consisting of the reacting of 1 to 20 parts (w/w) of beta-blocking agent (oxprenolol, pindolol, sotalol, metoprolol, alprenolol, acebutolol, atenolol, bopindolol, practolol, nadolol or propranolol) in 100 parts of an aqueous solution with 0.001 to 10.0 parts of a polysaccharide polymer, advantageously with Xanthan Gum having beta-1,4-glucan chain, or dextran, or amylodextrin, or carboxymethylamylum. The reaction is allowed to take place in the course of 20 minutes at a pH adjusted no 2.0-4.5, with vigorous stirring at 80.degree. C. temperature. Following the usual method of the pharmaceutical practice, the system is then formulated by the addition of water to obtain a solution suitable for oral administration.Type: GrantFiled: October 14, 1993Date of Patent: January 16, 1996Assignee: Synepos AktiengesellschaftInventors: Istvan Racz, Sylvia Marton
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Patent number: 5468716Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.Type: GrantFiled: October 3, 1994Date of Patent: November 21, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5466469Abstract: A novel granular drug delivery system having a gel-forming dietary fiber that can be made into a an orally-ingestible dispersion by admixture with a liquid that can deliver an effective dose of a pharmaceutically-active compound. The granular drug delivery system comprises granules consisting essentially of a pharmaceutically active compound, and a gel-forming dietary fiber, the granules being coated with at least one of the following: a gel-forming dietary fiber, a starch or a protein. The composition may further include a mineral salt that releases a physiologically-acceptable gas upon ingestion. The composition of the granular drug delivery system will deliver microgram quantities of a pharmaceutically-active compound in an orally-ingestible dispersion without forming a thick gel and without forming "hot" and "cold" spots of the pharmaceutically-active compound.Type: GrantFiled: March 28, 1994Date of Patent: November 14, 1995Assignee: Cibus Pharmaceutical, Inc.Inventor: Eric H. Kuhrts
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Patent number: 5464805Abstract: The present invention provides a method for controlling mildew in cultivated crops. The aqueous fungicide formulation which is applied to pre-harvest and post-harvest crops contains ingredients which are biocompatible for purposes of agricultural and horticultural applications. Illustrative of a formulation which is harmless to animals and humans is an aqueous solution having a content of potassium bicarbonate, potassium carbonate, potassium oleate and xanthan gum. The combination of potassium oleate and xanthan gum functions as an effective spreader-sticker medium for forming a solid coating on plant surfaces. The solid coating exhibits both immediate and long duration fungicidal activities.Type: GrantFiled: March 23, 1995Date of Patent: November 7, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5464874Abstract: A surfactant having an elevated viscosity is prepared with thickeners comprising an alkyl polyglycosides, polymer and optionally, a foreign electrolyte.Type: GrantFiled: August 22, 1994Date of Patent: November 7, 1995Assignee: Huels AktiengesellschaftInventor: Dieter Balzer
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Patent number: 5462749Abstract: Bioadhesive pharmaceutical carrier consisting essentially of a polymer blend of sodium carboxymethyl cellulose and xanthan gum or sodium alginate. The invention also provides for a method of control releasing a pharmaceutical active comprising incorporating an active into the bioadhesive pharmaceutical carrier. The invention is particularly adaptable for oral use and teething gels.Type: GrantFiled: April 26, 1994Date of Patent: October 31, 1995Assignee: McNell-PPC, Inc.Inventor: William F. Rencher
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Patent number: 5461081Abstract: Universal ophthalmic pharmaceutical vehicles which increase in viscosity upon instillation in the eye are disclosed. Ophthalmic compositions of the universal vehicle and a pharmaceutically active drug are also disclosed. In one embodiment, the vehicle gels upon instillation in the eye. In another embodiment, suspension vehicles having superior physical stability are provided.Type: GrantFiled: January 7, 1994Date of Patent: October 24, 1995Assignee: Alcon Laboratories, Inc.Inventors: Yusuf Ali, Kenneth W. Reed
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Patent number: 5455050Abstract: The present invention relates to an aqueous pharmaceutical suspension for oral use, and a method of preparation, having antacid and antiulcer properties which contains a therapeutically effective amount of calcium carbonate in combination with magnesium carbonate and/or magnesium trisilicate and a carboxylic acid pH adjusting agent.Type: GrantFiled: November 12, 1993Date of Patent: October 3, 1995Assignee: McNeil-PPC, Inc.Inventors: Douglas S. Beyerle, Gerard P. McNally
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Patent number: 5446070Abstract: Compositions for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a pharmaceutically acceptable carrier, and a solvent for the pharmaceutical agent(s) in the carrier and methods of administering the pharmaceutical agents to a mammal are disclosed.Type: GrantFiled: August 27, 1993Date of Patent: August 29, 1995Assignee: Nover Pharmaceuticals, Inc.Inventor: Juan A. Mantelle
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Patent number: 5432146Abstract: The present invention provides a fungicidal fertilizer composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, potassium oleate, xanthan gum and a fertilizer-effective content of nitrogen, phosphorus and potassium elements. The combination of potassium oleate and xanthan gum functions as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications. When the aqueous medium is hard water, calcium oleate is formed which enhances the sticker properties of the aqueous fungicide composition in agricultural applications.Type: GrantFiled: December 20, 1993Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5432148Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: December 7, 1994Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5432147Abstract: The present invention provides a method for controlling fungal disease in cultivated crops. The aqueous fungicide formulation which is applied to pre-harvest and post-harvest crops contains ingredients which are biocompatible for purposes of agricultural and horticultural applications. Illustrative of a formulation which is harmless to animals and humans is an aqueous solution having a content of potassium bicarbonate, potassium carbonate, nonionic surfactant and xanthan gum. The combination of nonionic surfactant and xanthan gum functions as an effective spreader-sticker medium for forming a film-like coating on plant surfaces. The adherent coating exhibits both immediate and long duration fungicidal activities.Type: GrantFiled: October 19, 1994Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventors: Anthony E. Winston, Alfredo Vinci
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Patent number: 5425952Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: October 13, 1993Date of Patent: June 20, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5424270Abstract: The present invention provides a method for controlling fungal disease in plants with a fungicidal fertilizer composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. Illustrative of an invention composition is an aqueous solution which has a content of two alkali metal bicarbonate salts, an alkali metal fatty acid salt, and a water-soluble thickener such as xanthan gum. The combination of fatty acid salt and thickener functions as an effective spreader-sticker medium.Type: GrantFiled: July 7, 1993Date of Patent: June 13, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5415877Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.Type: GrantFiled: December 22, 1993Date of Patent: May 16, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5409907Abstract: The present invention relates to an aqueous pharmaceutical suspension composition comprising: from about 0.2% to 20% of a substantially water soluble pharmaceutical active, e.g. acetaminophen; a suspension stabilizing effective amount of xanthan gum and microcrystalline cellulose; an effective amount of taste masking compositions; and water, as well as a process for producing such aqueous pharmaceutical suspensions.Type: GrantFiled: December 16, 1993Date of Patent: April 25, 1995Assignee: McNeil-PPC, Inc.Inventors: Cynthia M. Blase, Manoj N. Shah
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Patent number: 5395851Abstract: A coating composition for application to tree wounds, such as pruning wounds of living trees is provided. The composition is non-phytotoxic and provides extended protection against fungal pathogens. The coating composition comprises a liquid carrier together with a fatty acid metal salt active ingredient. Exemplary fatty acid metal salts include those prepared from alpha monocarboxylic acids having from 4 to 18 carbon atoms and a compound containing a metal selected from the group consisting of calcium, copper, iron, magnesium, and zinc. Various additives can be included within the composition, including gum-like substances and binders suitable to facilitate the adhesion of the active ingredient to the tree surface, as well as defoaming agents and other formulation enhancing agents.Type: GrantFiled: July 16, 1993Date of Patent: March 7, 1995Assignee: W. Neudorff GmbH KGInventor: Frederick S. Sedun
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Patent number: 5389386Abstract: The present invention provides a method for controlling fungal disease in cultivated crops. The aqueous fungicide formulation which is applied to pre-harvest and post-harvest crops contains ingredients which are biocompatible for purposes of agricultural and horticultural applications. Illustrative of a formulation which is harmless to animals and humans is an aqueous solution having a content of potassium bicarbonate, potassium carbonate, nonionic surfactant and xanthan gum. The combination of nonionic surfactant and xanthan gum functions as an effective spreader-sticker medium for forming a film-like coating on plant surfaces. The adherent coating exhibits both immediate and long duration fungicidal activities.Type: GrantFiled: June 30, 1994Date of Patent: February 14, 1995Assignee: Church & Dwight Co., Inc.Inventors: Anthony E. Winston, Alfredo Vinci
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Patent number: 5362495Abstract: The present invention has for its object an insert material used for widening the gingival sulcus, substantially without bleeding or oozing, particularly in order to make a cast for a dental prosthesis.According to the invention, this material takes the form of a biocompatible paste which is injectable for external use and preferably hydrophilic, whose viscosity is of between about 13000 and about 30000 Pascals.second.Application: dental surgery.Type: GrantFiled: December 10, 1991Date of Patent: November 8, 1994Inventor: Patrick Lesage
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Patent number: 5340591Abstract: A solid dispersion and a method of producing a solid dispersion of a sparingly water-soluble drug characterized by mixing the sparingly water-soluble drug and a water-soluble polymer at a temperature where neither the water-soluble drug nor water-soluble polymer is melted.Type: GrantFiled: January 4, 1993Date of Patent: August 23, 1994Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Minoru Nakano, Toshinobu Uemura, Shinichi Morizane, Kiyoshi Okuda, Keiko Nakata
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Patent number: 5334390Abstract: Method for alleviating symptoms of nicotine withdrawal employing calcium carbonate.Type: GrantFiled: November 5, 1992Date of Patent: August 2, 1994Inventors: Neil Solomon, Theodore C. Solomon, Allen J. Freed
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Patent number: 5332576Abstract: A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, bioadhesive carrier, and a solvent for the pharmaceutical agent(s) in the carrier and a method of administering the pharmaceutical agent to a mammal are disclosed.Type: GrantFiled: May 21, 1993Date of Patent: July 26, 1994Assignee: Noven Pharmaceuticals, Inc.Inventor: Juan A. Mantelle
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Patent number: 5320847Abstract: A high-fiber, consumable bulk fiber composition, which may be used as a laxative, comprises powdered psyllium husks agglomerated with a water soluble, low viscosity gum, preferably gum acacia, to form a dry, free-flowing, water dispersible dietary fiber combinate. To form the dietary fiber combinate, the powdered psyllium husks are mixed with an aqueous solution of the water soluble, low viscosity gum, preferably by fluid bed agglomeration, and dried. The composition is employed to treat constipation by ingesting an effective amount of the dietary fiber combinate dispersed in water.Type: GrantFiled: May 13, 1993Date of Patent: June 14, 1994Assignee: Valentine Enterprises, Inc.Inventors: William Valentine, William K. Valentine
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Patent number: 5306506Abstract: The invention provides a solid pharmaceutical composition for addition to water to produce a suspension of a drug comprising (a) a drug which is substantially water-insoluble or microencapsulated; (b) a thickening or suspending agent; (c) a pharmaceutically acceptable acid; (d) a pharmaceutically acceptable carbonate or bicarbonate; characterised in that the weight ratio of c+d:b is from 1:1.5 to 1:15 and the amount of c+d is sufficient to obtain rapid hydration of the thickening or suspending agent (b) when the composition is mixed with water such that a homogeneous suspension of the drug is obtained within 30 seconds. A method for preparing the composition is also described.Type: GrantFiled: March 3, 1992Date of Patent: April 26, 1994Assignee: Eurand International S.p.A.Inventors: Marco Zema, Luigi G. Mapelli, Marco G. Marconi
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Patent number: 5300302Abstract: A pharmaceutical active principle delivery system has a pharmaceutical active principle contained in solution or solid form in an excipient gel formed with gelling agents which provide for a pseudoplastic and more or less thixotropic water-dispersible gel which may be packed in a dispenser having a metering pump for delivering therapeutic doses of the composition.Type: GrantFiled: September 9, 1991Date of Patent: April 5, 1994Assignee: Nestec S.A.Inventors: Pierre Tachon, Beatrice Vagneur, Jean-Louis Viret
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Patent number: 5292518Abstract: A prolonged-release unit dosage formulation or pharmaceutical composition, preferably in tablet form, is described. The composition consists essentially of a gel-forming dietary fiber, a biologically-absorbable drug or other active therapeutic agent, and a disintegrant, namely, a mineral salt which releases a physiologically-acceptable gas upon ingestion, preferably carbon dioxide, e g., a mineral carbonate or bicarbonate, and advantageously dextrose or like soluble sugar. A physiologically-acceptable acid may optionally be included in the composition to further facilitate disintegration. The dietary fiber-containing composition, when compressed into a tablet together with the drug and the specific disintegrants, provides a unique and efficient prolonged-action drug-delivery system.Type: GrantFiled: March 16, 1992Date of Patent: March 8, 1994Assignee: Hauser-KuhrtsInventor: Eric H. Kuhrts
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Patent number: 5284655Abstract: Swollen demineralized bone particles are formulated into a flowable osteogenic composition which is useful in the repair of osseous defects.Type: GrantFiled: February 4, 1992Date of Patent: February 8, 1994Assignee: Osteotech, Inc.Inventors: Simon Bogdansky, Robert K. O'Leary
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Patent number: 5272137Abstract: The present invention relates to an aqueous pharmaceutical suspension composition comprising: from about 0.2% to 20% of a substantially water soluble pharmaceutical active, e.g. acetaminophen; a suspension stabilizing effective amount of xanthan gum and microcrystalline cellulose; an effective amount of taste masking compositions; and water, as well as a process for producing such aqueous pharmaceutical suspensions.Type: GrantFiled: February 14, 1992Date of Patent: December 21, 1993Assignee: McNeil-PFC, Inc.Inventors: Cynthia M. Blase, Manoj N. Shah
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Patent number: 5260279Abstract: A nutritionally complete feeding composition contains soluble fiber, especially hydrolyzed guar gum or pectin. This composition provides nourishment to colon cells, preventing bacterial sepsis and also preventing diarrhea.Type: GrantFiled: May 4, 1992Date of Patent: November 9, 1993Assignee: Sandoz Ltd.Inventor: Norman A. Greenberg
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Patent number: 5252340Abstract: A method of producing an absorbent composition. A polymeric material characterized as having surface anionic reactive sites is mixed with a source of multivalent metal ions to render the polymeric material sorbent of aqueous liquids. A dispersant is then added to form a wet slurry which is subsequently dried to a granular consistency.Type: GrantFiled: April 28, 1992Date of Patent: October 12, 1993Assignee: Isolyser Company, Inc.Inventor: Travis W. Honeycutt
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Patent number: 5236703Abstract: A polymeric substrate such as rubber or latex incorporates povidone-iodine as a control release biologically active agent.Type: GrantFiled: July 20, 1989Date of Patent: August 17, 1993Assignee: Virex Inc.Inventor: Anton-Lewis Usala
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Patent number: 5234957Abstract: A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, bioadhesive carrier, and a solvent for the pharmaceutical agent(s) in the carrier and a method of administering the pharmaceutical agent to a mammal are disclosed.Type: GrantFiled: December 23, 1991Date of Patent: August 10, 1993Assignee: Noven Pharmaceuticals, Inc.Inventor: Juan A. Mantelle
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Patent number: 5208028Abstract: The present invention relates to gelled emulsion particles obtained when predetermined volumes, especially drops, of an emulsion with an aqueous external phase, containing an appropriate reagent in solution in the said aqueous phase, are added to a gelling solution and left therein for a period of time which depends on the degree of gelling desired for the said particles. It further relates to compositions-especially solutions, gels or emulsions with an aqueous external phase-in which the said particles are present.Type: GrantFiled: March 29, 1989Date of Patent: May 4, 1993Assignee: Helena Rubinstein, Inc.Inventors: Anne Clement, Pierre Fodor, Gerard Guth, Nathalie Thiollet
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Patent number: 5196190Abstract: Membranes suitable for use as wound dressings and in particular as synthetic skin substitutes are disclosed. The membranes consist of a natural or synthetic polymer, a non-gellable polysaccharide and a cross-linking agent.The membranes of the invention may contain one or more additional components selected from water-loss control agents, emulsifying agents and plasticizers. An internal reinforcing material may also be provided to supplement the inherent mechanical strength of the membrane.Methods of forming such membranes are also disclosed.Type: GrantFiled: October 3, 1990Date of Patent: March 23, 1993Assignee: Zenith Technology Corporation, LimitedInventors: Avinash Nangia, Cheung-Tak Hung
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Patent number: 5194253Abstract: An aqueous gel based on hyaluronic acid and on deoxyribonucleic acid usable in cosmetics, and a method of preparation.The invention relates to an aqueous gel formed by a homogeneous mix of:a) an alkaline salt or an ammonium salt of hyaluronic acid in the form of an aqueous gel;b) a mineral or organic salt of high molecular weight deoxyribonucleic acid in the form of an aqueous gel;c) at least one hydrophilic polymer having the property of forming aqueous film-forming gels.Application to the preparation of masks in cosmetics.Type: GrantFiled: May 9, 1990Date of Patent: March 16, 1993Assignee: Pier Auge (Societe Anonyme)Inventor: Ricardo Garrido
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Patent number: 5192544Abstract: Cosmetic or pharmaceutical composition consisting of a dispersion in a physiologically acceptable aqueous phase D of vesicles of ionic and/or nonionic amphiphilic lipid(s), the vesicles being bounded by one or more lipid lamellae, the lipid lamellae containing at least one retinoid compound and the aqueous dispersion phase a pyrimidine derivative. The said composition may be used by topical application on the hair and scalp.Type: GrantFiled: October 11, 1990Date of Patent: March 9, 1993Assignee: L'OrealInventors: Jean-Francois Grollier, Georges Rosenbaum, Isabelle Richoux
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Patent number: 5188825Abstract: A method of preparing a freeze-dried dosage form including a water soluble active agent is disclosed. The water soluble active agent is bonded to an ion exchange resin to form a substantially water insoluble complex. This complex is then mixed with a compatible carrier and freeze-dried. The resulting freeze-dried dosage form contains an effective unit dosage amount of the active agent and exhibits enhanced compositional and physical stability, as well as permitting processing according to conventional freeze-drying techniques.Type: GrantFiled: December 28, 1989Date of Patent: February 23, 1993Inventors: Martin C. Iles, Angela D. Atherton, Neil M. Copping
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Patent number: 5169633Abstract: The invention relates to compositions for the parenteral administration of an essentialy uniform and continuous amount of a phenylethanolamine derivative over an extended period of time. The invention also relates to the preparation and administration of said compositions.Type: GrantFiled: August 2, 1991Date of Patent: December 8, 1992Assignee: American Cyanamid CompanyInventors: Richard Fishbein, Susan M. Cady, Ajit K. Chaudhuri
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Patent number: 5154926Abstract: The present invention relates to a syrup composition characterized in that the composition contains phenobarbital or acetaminophen, a polyhydric alcohol and/or a polymer of a polyhydric alcohol, and a water soluble macromolecule, and the weight ratio of phenobarbital to the polyhydric alcohol and/or the polymer of the polyhydric alcohol is from 1:20 to 1:100, and the weight ratio of phenobarbital to the water soluble macromolecule is from 1:1 to 1:20, which has a reduced bitterness and is easy to take.Type: GrantFiled: February 6, 1991Date of Patent: October 13, 1992Assignee: Showa Yakuhin Kako Co., Ltd.Inventors: Yoshihiko Kawasaki, Yukio Suzuki
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Patent number: 5147651Abstract: There is disclosed a composition useful for medicated treatment of hooves of live animals. The composition comprises a major portion of a carrier and hoof penetrant, a minor amount of a filler comprising chiefly polyolefin fibers, and an oil-in-water emulsifier to form a staple composition. The composition can include optional quantities of a medicinal compound. A specific example of the compound comprises approximately 12 weight percent of chopped fibers of a polyolefin such as polyethylene or polypropylene, about 69 percent of a carrier comprising pine tar, paraffin wax and coconut oil, and an oil-in-water emulsifier such as an aliphatic alcohol or alkyl glucose fatty acid ester. Preferably, the composition also includes a medicinal compound such as alcohol, iodine or a soluble iodide. The method comprises packing the hooves of live animals such as horses with the composition.Type: GrantFiled: April 23, 1990Date of Patent: September 15, 1992Inventors: Don R. Hobson, Edwin L. Kinney
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Patent number: 5141741Abstract: A novel anti-sunburn skin-care preparation, such as creams, foundations, milky lotions and the like, is proposed which contains, as the ultraviolet-absorbing and -shielding ingredient, a salt of ellagic acid with a polyvalent metal, e.g., calcium, barium and magnesium. The skin-care preparation is free from the problem of irritation and sensitization of human skin and exhibits excellent anti-sunburn effect with durability.Type: GrantFiled: December 4, 1989Date of Patent: August 25, 1992Assignee: Lion CorporationInventors: Keiichiro Ishida, Yoshimi Sato, Makoto Egawa, Keiji Takeuchi
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Patent number: 5139771Abstract: A face masque composition useful for treating human skin for improvement comprising about 1-70% of a hydrolzed grain endproduct, about, 0.1-15% of a seaweed derivative and about 20-95% water.Type: GrantFiled: February 11, 1992Date of Patent: August 18, 1992Assignee: Revlon, Inc.Inventor: Terry Gerstein
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Patent number: 5118510Abstract: A readily-dispersible physiologically-effective fiber drink mix containing granules which are a blend of a mineral salt which releases a physiologically-acceptable gas upon ingestion, a physiologically-acceptable edible acid, and a gel-forming dietary fiber, and which granules are coated with a gel-forming dietary fiber, starch, or protein, are disclosed. The resulting granules can be mixed into water or juice for ingestion. They readily disperse into solution and do not immediately gel up and solidify, but become activated when they reach the acid environment of the stomach and dissolve, at which time the internally-contained acid and mineral salt cooperate to mechanically disperse the fiber in a slow and prolonged manner as it hydrates, the gas released by the mineral salt and the organic acid assisting in slow disintegration of the granules. An orally-ingestible pharmaceutically-active compound, e.g.Type: GrantFiled: November 22, 1989Date of Patent: June 2, 1992Assignee: Hauser-Kuhrts, Inc.Inventor: Eric H. Kuhrts
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Patent number: 5093130Abstract: Methods and materials are provided for coating hydrogel capsules containing botanic tissue with an inert substance that decrease capsule surface adhesiveness and facilitates singulation and flowability of the hydrogel capsules. The coating may be composed of at least one hydrophobic powder capable of forming a discontinuous film about the capsule surface.Type: GrantFiled: September 26, 1989Date of Patent: March 3, 1992Assignee: Plant GeneticsInventors: Jon A. Fujii, Keith Redenbaugh, Yuji Sakamoto
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Patent number: 5069898Abstract: This invention provides a hair enrichment composition which includes a hair-sorbable bulking agent, a blood vessel dilator, and a scalp stimulant, together with a method of using the composition.Type: GrantFiled: April 24, 1989Date of Patent: December 3, 1991Assignee: Revlon, Inc.Inventor: Marvin E. Goldberg
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Patent number: 5068108Abstract: This invention concerns compositions for zootechnical and veterinary use, characterized in that biologically active substances are incorporated in protective matrices, which have the following properties: 1) controlled release (ruminal by-pass) effect; 2) chemical-physical protection of active principles against degradation induced by technological processes of production, storage and pellettization of fodders for all animal species. The matrices of the invention are characterized by a plastic rheological behaviour due to the presence of lipogelling agents. The obtained products show the following advantages: increased active principle stability in feeds for all animal species; protection of the active principles from attack of Rumen microorganisms in fodder from attack of for ruminants.Type: GrantFiled: February 27, 1990Date of Patent: November 26, 1991Assignee: Industria Italiana Integratori Trei S.p.A.Inventors: Luigi Fezzi, Giacomo Grassigli
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Patent number: 5059422Abstract: The invention relates to compositions for the parenteral administration of an essentially uniform and continuous amount of a phenylethanolamine derivative over an extended period of time. The invention also relates to the preparation and administration of said compositions.Type: GrantFiled: June 25, 1990Date of Patent: October 22, 1991Assignee: American Cyanamid CompanyInventors: Richard Fishbein, Susan M. Cady, Ajit K. Chaudhuri
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Patent number: 5030444Abstract: The invention concerns a process for making a toothpaste containing an abrasive agent and a binder consisting wholly or partly of guar gum or other plant gum. The plant gum is hydrated by a liquid hydration medium consisting of water and 0 to 33% by weight of the hydration medium of sorbitol. To hydrate the plant gum it is mixed with the hydration medium in the presence of sufficient of the abrasive agent to produce enough shear to give a smooth cream. Other conventional ingredients are then mixed in.Type: GrantFiled: July 21, 1989Date of Patent: July 9, 1991Assignee: Chesebrough-Pond's USA Co., division of Conopco, Inc.Inventors: Ronald Hoyles, Andrew E. Wilde
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Patent number: 5013763Abstract: A skin preparation such as skin lotion or cream which is resistant to being removed when the skin is washed includes a skin-preparation base and a plurality of wash-off-resistance substantivity agents. The wash-off-resistance substantivity agents include a polymeric skin-feel-modifying compound, a quanternary ammonium compound, a hydrophobic modified starch, a substantive silicone and a substantive emollient.Type: GrantFiled: November 30, 1987Date of Patent: May 7, 1991Assignee: The Andrew Jergens CompanyInventors: David R. Tubesing, Maxine L. Truax
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Patent number: 5002974Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: March 26, 1991Assignee: Warner-Lambert Co.Inventor: Navin M. Geria