Carboxylic Acid Ester Patents (Class 514/785)
  • Patent number: 10434043
    Abstract: The present invention provides a water-in-oil emulsion solid cosmetic that is further improved in terms of an excellent feeling in use (good spreadability and fresh feeling (texture)) obtained by incorporating a powder in a water phase, and that also has sufficient covering ability, stability even at high temperature, and long-lasting property. The present invention provides a water-in-oil emulsion solid cosmetic comprising an external oil phase comprising a liquid oil thickened or solidified with (A) wax and (B) disteardimonium hectorite, and an internal water phase comprising (C) an internal phase powder dispersed in an aqueous medium.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: October 8, 2019
    Assignee: SHISEIDO COMPANY, LTD.
    Inventors: Shoji Tajima, Tomoko Ikeda
  • Patent number: 10406135
    Abstract: Compositions comprising isosorbide monoesters and alcohols comprising at least one aromatic group What are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more alcohols comprising at least one aromatic group. The compositions are distinguished in particular by an advantageous antimicrobial activity.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: September 10, 2019
    Assignee: Clariant International Ltd.
    Inventors: Maurice Frederic Pilz, Peter Klug, Franz-Xaver Scherl, Joerg Grohmann
  • Patent number: 10370618
    Abstract: Aqueous surfactant compositions containing one or more alpha-sulfo fatty acid disalts (A) of the general formula (I), R1CH(SO3M1)COOM2??(I), in which the radical R1 is a linear or branched alkyl or alkenyl radical with 6 to 18 carbon atoms and the radicals M1 and M2, independently of one another, are selected from the group H, Li, Na, K, Ca/2, Mg/2, ammonium and alkanolamines, one or more N-acylglutamic acid compounds (B) of the general formula (II), M3OOC—CH2—CH2—CH(NH—CO—R2)—COOM4??(II) in which the radical R2 is a linear or branched alkyl or alkenyl radical with 7 to 19 carbon atoms and the radicals M3 and M4, independently of one another, are selected from the group H, Li, Na, K, Ca/2, Mg/2, ammonium and alkanolamines, and water, with specific limiting conditions, are disclosed. The compositions are transparent, storage-stable, exhibit good foaming ability, and are suitable for cosmetic products, detergents, and cleaners.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: August 6, 2019
    Assignee: BASF SE
    Inventors: Ansgar Behler, Claudia Brunn, Detlev Stanislowski
  • Patent number: 10016510
    Abstract: The present invention relates to an immunogenic composition comprising a continuous aqueous phase and a dispersed phase as droplets and comprising: an amphiphilic lipid, a solubilizing lipid comprising at least one fatty acid glyceride, a co-surfactant comprising at least one chain consisting of alkylene oxide units, a surfactant bearing an antigen of the following formula (I): (L1-X1—H1—Y1)v-G-Z1—Ag??(I), to its preparation method and its uses, notably for producing antibodies, as a drug or in an immunization method.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: July 10, 2018
    Assignee: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES
    Inventors: Fabrice Navarro Y Garcia, Thomas Courant, Isabelle Texier-Nogues, Patrice Marche
  • Patent number: 9937188
    Abstract: Disclosed herein are emulsions comprising testosterone or related androgens, castor oil, cyclodextrin, Pemulen TR-2, Polyoxyl 40, and other ingredients. The compositions are useful for treating keratoconjunctivitis sicca and meibomian gland disease.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: April 10, 2018
    Assignee: Allergan, Inc.
    Inventors: John T. Trogden, Adnan K. Salameh, Chetan P. Pujara, Anuradha V. Gore, Jaya Giyanani, Andrea S. Kim, Mayssa Attar, Ronald Bradford, Rhett M. Schiffman
  • Patent number: 9890348
    Abstract: A metathesized natural oil composition comprising (i) a mixture olefins and/or esters, or (ii) a metathesized natural oil, is disclosed. The metathesized natural oil composition has a number average molecular weight in the range from about 100 g/mol to about 150,000 g/mol, a weight average molecular weight in the range from about 1,000 g/mol to about 100,000 g/mol, a z-average molecular weight in the range from about 5,000 g/mol to about 1,000,000 g/mol, and a polydispersity index of about 1 to about 20. The metathesized natural oil composition is metathesized at least once.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: February 13, 2018
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Steven A. Cohen, M. Michelle Morie-Bebel, Alexander D. Ilseman, Benjamin Bergmann, Stephen A. DiBiase, S. Alexander Christensen
  • Patent number: 9820932
    Abstract: The present invention relates to cosmetics comprising a hydroxyl compound obtained by the reaction of a di- or higher-valent alcohol with a monovalent carboxylic acid and dimer acid, characterized in that the hydroxyl compound is obtained by reacting diglycerin with isostearic acid, and then reacting the obtained ester compound with dimer acid, wherein a molar ratio among diglycerin, isostearic acid and dimer acid is in the range of 1.0:1.4 to 1.6:0.5 to 0.8. The present invention provides cosmetics comprising the hydroxyl compounds having a high hydroxyl value.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: November 21, 2017
    Assignee: KOKYU ALCOHOL KOGYO CO., LTD.
    Inventors: Kyoichi Takeda, Yuki Kokeguchi, Mari Yoshida, Kiyoshi Maeno
  • Patent number: 9714209
    Abstract: A method for preparing an estolide compound and an estolide compound prepared thereby are disclosed. The method for preparing an estolide compound includes: converting biomass fat into a fatty acid; separating the fatty acid into a C16 saturated fatty acid and a C18 unsaturated fatty acid; preparing a linear internal olefin (LIO); increasing an amount of oleic acid through partial hydrogenation of the C18 unsaturated fatty acid; synthesizing an estolide polymer through cross metathesis of the oleic acid; capping the C16 saturated fatty acid onto the estolide polymer; and reacting the estolide polymer with the linear internal olefin.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: July 25, 2017
    Assignees: SK Innovation Co., Ltd., SK Lubricants Co., Ltd.
    Inventors: Yong Woo Kim, Hee Jung Jeon, Wan Seop Kwon, Hak Mook Kim, Jin Hee Ok
  • Patent number: 9617499
    Abstract: Disclosed is a method of producing an estolide, including a) converting biomass-derived oil into a fatty acid mixture, b) separating the fatty acid mixture into a C16 saturated fatty acid and a C18 unsaturated fatty acid, c) converting the C16 saturated fatty acid into a C15 or C16 linear internal olefin, d) subjecting the C15 or C16 linear internal olefin to an estolide reaction using a linking agent, thus obtaining an estolide A, e) subjecting the C18 unsaturated fatty acid to partial hydrogenating to increase the amount of oleic acid, and f) subjecting the oleic acid to an estolide reaction using a linking agent and then esterification, thus obtaining an estolide B.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 11, 2017
    Assignees: SK INNOVATION CO., LTD., SK LUBRICANTS CO., LTD.
    Inventors: Hee Jung Jeon, Jong Su Lee, Yong Woo Kim
  • Patent number: 9532586
    Abstract: The present invention provides a reduced sodium composition comprising at least one potassium salt, at least one sodium salt, at least one emulsifier and at least one thickening agent. For example, the reduced sodium composition comprises at least: one potassium salt, at least one sodium salt, glycerol monostearate and maltodextrin as well as to its method of preparation. The reduced sodium composition is used for enhancing the flavor of food, as a food seasoning, food condiment and/or food additive and provides a healthier alternative to the consumer, in particular where reducing the sodium in the diet is beneficial for health.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: January 3, 2017
    Assignee: HOLISTA BIOTECH SDN. BHD.
    Inventors: Christiani Jeya Kumar Henry, M. Rajendran a/l V. Marnickavasagar
  • Patent number: 9493725
    Abstract: The present invention relates generally to detergent compositions and, more specifically, to detergent compositions containing a branched surfactant.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: November 15, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Phillip Kyle Vinson, Patrick Christopher Stenger, Randall Thomas Reilman, Jeffrey John Scheibel, Praveen Kumar Depa, Stephanie Ann Urbin, Melinda Phyllis Steffey, Clemens Schröder
  • Patent number: 9090538
    Abstract: The use of an esteramide compound, alone or as a mixture of the following formula (I): R1OOC-A-CONR2R3??(I) is described, wherein: A is a covalent bond or a methylene group —CH2—, R1 is an optionally substituted hydrocarbon group having from 1 to 36 carbon atoms, R2 and R3, either identical or different, are groups selected from a hydrogen atom and optionally substituted hydrocarbon groups comprising from 1 to 36 carbon atoms, R2 and R3 may form together a ring having the nitrogen atom to which they are bound, said ring being, if need be, substituted and/or having an additional heteroatom and R2 and R3 not being simultaneously hydrogens. Also described, are applications for using the esteramide compound as a solvent, a co-solvent, a coalescence agent, a crystallization inhibitor, a plasticizer or an agent for increasing biological activity.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: July 28, 2015
    Assignee: RHODIA OPERATIONS
    Inventors: Massimo Guglieri, Thierry Vidal
  • Publication number: 20150148431
    Abstract: A composition suitable for use in a transdermal delivery patch for administration of a biologically active compound, the composition comprising a phosphate compound of tocopherol and a polymer carrier.
    Type: Application
    Filed: November 21, 2014
    Publication date: May 28, 2015
    Inventors: Jeremy Cottrell, Giacinto Gaetano, Mahmoud El-Tamimy, Nicholas Kennedy, Paul David Gavin
  • Publication number: 20150136150
    Abstract: Disclosed herein are methods and compositions of durable skin marking compositions that remains legible and visible on the skin after being treated with an aqueous, alcohol-based solution. The skin marking composition of the present invention includes a cyanoacrylate component, a solvent, and a colorant. The composition can further comprise one or more of viscosity modifiers/thickening agents, stabilizers, plasticizers, formaldehyde scavengers, polymerization accelerators, perfumes, adhesion promoters, and antibacterial, anti-fungal, anti-viral, or anti-microbial agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 5, 2012
    Publication date: May 21, 2015
    Applicant: OP-MARKS, INC.
    Inventors: Stephen Bruce Lober, Ian Askill
  • Publication number: 20150126616
    Abstract: N-methyl-N-acylglucamines are suitable as thickening agents in aqueous surfactant solutions containing one or more anionic surfactants of the group including alkyl ether sulfates and alkyl sulfates, the N-methyl-N-acylglucamines containing at least 60 wt.-% of N-methyl-N-acylglucamines that have a C12-, C14-acyl group or an unsaturated C18-acyl group and at the same time less than 5 wt.-% of N-methyl-N-acylglucamines that contain an acyl group <C12. The surfactant solutions are particularly used in cosmetic compositions.
    Type: Application
    Filed: May 29, 2013
    Publication date: May 7, 2015
    Applicant: Clariant Finance (BVI) Limited
    Inventors: Peter Klug, Carina Mildner
  • Publication number: 20150118288
    Abstract: Lipid nanoparticle formulations, methods of making, and methods of using same are disclosed.
    Type: Application
    Filed: May 23, 2013
    Publication date: April 30, 2015
    Applicant: Ohio State Innovation Foundation
    Inventor: Robert J. Lee
  • Publication number: 20150110875
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.
    Type: Application
    Filed: July 10, 2014
    Publication date: April 23, 2015
    Inventors: Charles LINDER, Sarina GRINBERG, Eliahu HELDMAN
  • Patent number: 9005663
    Abstract: An exemplary embodiment of the invention is a method for making silver nanoparticles, and includes steps of reacting a silver salt with a phosphene amino acid to make silver nanoparticles. Exemplary phosphene amino acids include trimers, with a particular example being a trimeric amino acid conjugate containing one phosphene group. In an exemplary method of the invention, the silver nanoparticles may be produced in timer periods of less than about 30 minutes, and at temperatures of less than about 40° C. Other methods of the invention are directed to methods for stabilizing silver nanoparticles.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: April 14, 2015
    Assignee: The Curators of the University of Missouri
    Inventors: Kannan Raghuraman, Kattesh K. Katti
  • Publication number: 20150099809
    Abstract: Many fragrances that provide a scent of freshness tend to be highly volatile and are therefore not very economical when used in typical applications such as washing or cleaning processes, so they have to be used in relatively large quantities to be able to produce adequate effects. The disclosed photolabile pro-fragrances provide a much longer-lasting sense of fragrance, in particular with a scent of freshness, when used in typical applications, thus allowing said fragrances to be used efficiently.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Thomas Gerke, Christian Kropf, Ursula Huchel, Axel Griesbeck, Agnieszka Landes
  • Publication number: 20150094383
    Abstract: Synergistic surfactant blends are disclosed. In one aspect, the blend comprises an anionic surfactant and a metathesis-based cationic surfactant comprising a quaternized derivative. The quaternized derivative is a quaternized fatty amine, quaternized fatty amidoamine, imidazoline quat, or esteramine quat made from a metathesis-derived C10-C17 monounsaturated acid or its ester derivative. Also disclosed are synergistic surfactant blends comprising a cationic surfactant and a metathesisbased anionic surfactant comprising a sulfonated derivative. The sulfonated derivative is a fatty ester sulfonate, fatty acid sulfonate, sulfoestolide, fatty amide sulfonate, sulfonated fatty ester alkoxylate, imidazoline quat sulfonate, sulfonated amidoamine oxide, or sulfonated amidoamine betaine. The synergistic blends have a negative value or a reduced interfacial tension (IFT) when compared with an expected IFT value calculated from the individual surfactant components.
    Type: Application
    Filed: April 12, 2013
    Publication date: April 2, 2015
    Inventors: Randal J. Bernhardt, Xue Min Dong
  • Publication number: 20150093339
    Abstract: The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the “umami” taste of monosodium glutamate) or sweet taste modifiers,—savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.
    Type: Application
    Filed: October 8, 2014
    Publication date: April 2, 2015
    Inventors: Catherine TACHDJIAN, Andrew P. PATRON, Sara L. ADAMSKI-WERNER, Farid BAKIR, Qing CHEN, Vincent DARMOHUSODO, Stephen Terrence HOBSON, Xiaodong LI, Ming QI, Daniel H. ROGERS, Marketa RINNOVA, Guy SERVANT, Xiao-Qing TANG, Mark ZOLLER, David WALLACE, Amy XING, Klaus GUBERNATOR
  • Publication number: 20150094679
    Abstract: A lotion composition is provided. The lotion composition can comprise a) about 0.1% to about 90%, by weight, of a microcrystalline wax; b) about 0.1% to about 25%, by weight, of POE-4 monolaurate; c) about 0.1% to about 50%, by weight, of POE-8 monostearate; and d) a carrier.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Inventors: Robert Ya-lin Pan, Debora Christine Ebert, Peter Christopher Ellingson, Raphael Warren
  • Patent number: 8993641
    Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: March 31, 2015
    Assignee: Innolex Investment Corporation
    Inventor: Daniel Winn
  • Patent number: 8980835
    Abstract: A chemically modified water-soluble elastin that is obtained by subjecting to N-acylating some or all of the primary amines and secondary amines contained in the molecule of a high molecular weight water-soluble elastin and coupling some or all of the carboxyl groups contained in the molecule with the amino group of an amino acid alkyl ester. A chemically modified water-soluble elastin/collagen mixed gel obtained by mixing a collagen with a chemically modified water-soluble elastin that is obtained by subjecting to N-acylating some or all of the primary amines and secondary amines contained in the molecule of a high molecular weight water-soluble elastin and coupling some or all of the carboxyl groups contained in the molecule with the amino group of an amino acid alkyl ester.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: March 17, 2015
    Assignee: Kyushu Institute of Technology
    Inventors: Kouji Okamoto, Hiroshi Yamada, Yosuke Maegawa, Ryota Watanabe, Mitsuhiro Adachi
  • Publication number: 20150073476
    Abstract: The present invention relates to compositions comprising shape memory polymer (SMP) materials and uses thereof. Particularly, although not exclusively, the present invention relates to biocompatible shape memory polymer (SMP) materials and uses thereof in the medical field.
    Type: Application
    Filed: October 5, 2012
    Publication date: March 12, 2015
    Inventors: Malcolm Brown, Horacio Montes de Oca Balderas, Michael Andrew Hall, Alan William Bull, David Franklin Farrar, Philip Caton-Rose, Philip David Coates, Glen Thompson, Michael Martyn, Ian MacMillan Ward, Mark James Bonner, Peter John Hine, Paul Unwin, Robin Anthony Chivers, Michael Woodhead
  • Publication number: 20150064242
    Abstract: The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel, trialkyl, cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of a specific target protein at relatively low doses.
    Type: Application
    Filed: February 22, 2013
    Publication date: March 5, 2015
    Inventors: James Heyes, Mark Wood, Alan Martin
  • Patent number: 8968775
    Abstract: Provided are pharmaceutical carriers based on oil-in-water microemulsions and methods of making same. Also provided are pharmaceutical compositions comprising a carrier of the invention and a lipophilic active pharmaceutical ingredient (API), as well as methods for making same. The pharmaceutical compositions are particularly suitable for use in formulating lipophilic APIs for topical administration to the eye. Specifically included are pharmaceutical compositions comprising fenofibrate or fenofibric acid as API. Also provided is a method of treating a disease of the posterior segment of the eye. Also provided is a pharmaceutical composition comprising a compound represented by formulated for topical administration to the eye.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 3, 2015
    Assignee: EyeCRO, LLC
    Inventors: Ronald A. Wassel, Fadee G. Mondalek, Rafal A. Farjo, Alexander B. Quiambao, Didier J. Nuño
  • Patent number: 8969604
    Abstract: A surfactant composition for agricultural chemicals, containing fatty acid polyoxyalkylene alkyl ether expressed by the following general formula (I), R1CO(EO)m(PO)nOR2??(I) wherein the fatty acid polyoxyalkylene alkyl ether has a narrow ratio of 55% by mass or more, where the narrow ratio is expressed by the following formula (A): Narrow ratio=?i=nMAX?2i=nMAX+2Yi??(A).
    Type: Grant
    Filed: January 15, 2013
    Date of Patent: March 3, 2015
    Assignee: Lion Corporation
    Inventors: Akinori Kanetani, Hiroyuki Izumoto, Shiro Sato, Takaaki Kano
  • Publication number: 20150057374
    Abstract: A material including a continuous aqueous phase and a dispersed phase in the form of droplets containing an amphiphilic lipid and a surfactant having the following formula (I): (L1-X1—H1—Y1)v-G-(Y2—H2—X2-L2)w ??(I), wherein: L1 and L2 independently represent lipophilic groups, X1, X2, Y1, Y2 and G independently represent a linking group, H1 and H2 independently represent hydrophilic groups including a polyalkoxylated chain, v and w are independently an integer from 1 to 8, wherein the droplets of the dispersed phase are covalently bonded by the surfactant having the formula (I). The invention also relating to the method for preparing the same and to the uses thereof.
    Type: Application
    Filed: April 2, 2013
    Publication date: February 26, 2015
    Inventors: Anne-Claude Couffin, Thomas Delmas, Emilie Heinrich, Isabelle Texier-Nogues, Jean-Sébastien Thomann, Véronique Mourier
  • Publication number: 20150057373
    Abstract: Disclosed herein are novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. The cationic lipids can demonstrate enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver. The present invention employs low molecular weight cationic lipids with one short lipid chain coupled with inclusion of hydrolysable functionality in the lipid chains to enhance the efficiency and tolerability of in vivo delivery of siRNA.
    Type: Application
    Filed: March 25, 2013
    Publication date: February 26, 2015
    Applicant: SIRNA THERAPEUTICS, INC
    Inventors: Matthew G. Stanton, Brian W. Budzik, Steven L. Colletti
  • Patent number: 8962023
    Abstract: A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent. The curing method can vary the application of UV light in both intensity and duration to achieve a desired amount of cross-linking forming the gel.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: February 24, 2015
    Assignee: Atrium Medical Corporation
    Inventors: Roger Labrecque, Philip McNamara, Joseph Ferraro, Lisa Rogers, Paul Martakos, Theodore Karwoski, Steve A. Herweck, Keith Faucher, Thomas M. Swanick
  • Patent number: 8957116
    Abstract: To provide a solution for forming a double eyelid which enables extremely easy formation of a natural and ideal double eyelid without giving a displeased feeling or an uncomfortable feeling to a user, and a method for forming a double eyelid using the solution for forming a double eyelid. A solution for forming a double eyelid 1 according to the present invention is formed by dissolving, into a solvent having volatility, a fibrous material which forms a film 1a onto a skin 5a of an eyelid 5 and shrinks with vaporization of the solvent. By applying the solution 1, in a successive-curve form, over an imaginary line I forming a fold 5d of a double eyelid in the eyelid 5 onto which a user want to make a fold and vaporizing the solvent so as to shrink the film 1a, successive concaved groove-like constricted part 5c is formed on the imaginary line I and the fold 5d of a double eyelid along the constricted part 5c is formed.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: February 17, 2015
    Inventors: Naoko Iwagaki, Masayuki Kamagata, Jirou Taniyama
  • Publication number: 20150038592
    Abstract: The invention comprises a cosmetic and/or dermatological preparation based on water-in-oil emulsions, comprising at least two W/O emulsifiers and at least one oil having a spreadability value of more than 600 mm2/10 min.
    Type: Application
    Filed: February 12, 2013
    Publication date: February 5, 2015
    Inventors: Stephanie Von Der Fecht, Svenja Lena Moellgaard, Petra Koch, Isabel Balcke
  • Publication number: 20150030553
    Abstract: The use of one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms as thickeners is described. The use is preferably in cosmetic, dermatological or pharmaceutical compositions, in crop protection formulations, in washing or cleaning compositions or in paints or coatings.
    Type: Application
    Filed: July 31, 2012
    Publication date: January 29, 2015
    Applicant: CLARIANT INTERNATIONAL LTD.
    Inventors: Maurice Frederic Pilz, Peter Klug, Franz-Xaver Scherl
  • Publication number: 20150030684
    Abstract: An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are also provided. Also, kits including the irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are described.
    Type: Application
    Filed: October 13, 2014
    Publication date: January 29, 2015
    Inventors: Gregory J. Pomrink, Cecilia A. Cao, Zehra Tosun, David M. Gaisser
  • Publication number: 20150024022
    Abstract: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Inventors: Steven Bennett, Nathaniel Mast, Kevin Lavigne, Walter Skalla, Saumya Banerjee, Timothy Sargeant, Joshua Stopek
  • Publication number: 20150011661
    Abstract: The present invention relates to a fast curing compositions comprising a (meth)acrylamide functionalized hydrophilic silicone monomers having a polyether moiety containing a branched linking group. In one embodiment, such compositions are useful for preparing water-absorbing silicone-hydrogel films for contact lens applications. In one embodiment, the (meth)acrylamide monomers disclosed here have a branched linking group on the polyether moiety which makes it possible to produce hydrophilic polyether modified silicone copolymers without the need to separate various by-products including, but not limited to, unreacted, isomerized polyether and associated high molecular weight by-products.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 8, 2015
    Inventors: Anubhav Saxena, Shreedhar Bhat, Senthilkumar Umapathy, Kenrick M. Lewis
  • Publication number: 20150011599
    Abstract: The present invention describes a novel thickening composition that comprises a mixture of esters of an alkoxylated polyol and is used to enhance the viscosity of agrochemical formulations. The composition according to the present invention may present itself in solid for or in liquid form, in this latter case further comprising one or more surfactants, solvents, and optionally water. The thickening composition described in this invention is compatible with a large variety of pesticides and inert components used in agrochemical formulations, and it has evidence that it is capable of improving the stability and the effectiveness of the said formulations.
    Type: Application
    Filed: December 7, 2012
    Publication date: January 8, 2015
    Applicant: Oxiteno S.A. Indústria e Comércio Company
    Inventors: Oscar Osvaldo Hernandez Avila, Priscila Castelani
  • Publication number: 20150011654
    Abstract: Cosmetic and/or dermatological preparations based on a water-in-oil emulsion comprising at least two W/O emulsifiers which differ in their HLB value up to a maximum of 1 lead to sensorily acceptable preparations and at the same stable W/O emulsions.
    Type: Application
    Filed: February 12, 2013
    Publication date: January 8, 2015
    Inventors: Stephanie Von Der Fecht, Svenja Lena Moellgaard, Isabel Balcke, Petra Koch
  • Publication number: 20150005363
    Abstract: The present invention relates to a cationic lipid of formula (I) having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.
    Type: Application
    Filed: December 7, 2012
    Publication date: January 1, 2015
    Inventors: Steven M Ansell, Xinyao Du
  • Patent number: 8921430
    Abstract: The invention is directed to a mixture of esters according to the general formula (I), R1—C(?O)—O—R2, wherein R1 is an alkyl moiety with 7 to 9 carbon atoms and wherein R2 is a an alkyl moiety with 8 to 10 carbon atoms, wherein the mixture comprises 5 to 60 weight-% of ester of the general formula (I), wherein R1 is an alkyl moiety with 9 carbon atoms, based on the total amount of esters according to formula (I) and/or wherein the mixture comprises 5 to 60 weight-% of ester of the general formula (I), wherein R2 is an alkyl moiety with 10 carbon atoms, based on the total amount of esters according to formula (I). The invention is further directed to cosmetic and/or pharmaceutical compositions comprising such esters and processes for the production of such esters.
    Type: Grant
    Filed: June 19, 2010
    Date of Patent: December 30, 2014
    Assignee: Cognis IP Management GmbH
    Inventors: Rolf Kawa, Stefan Brüning
  • Publication number: 20140371333
    Abstract: An organogelling agent for forming reverse worm-like micelles having high safety to living bodies and the environment, favorable feel of use, and a high gelating ability and a thickened gel composition comprising the organogelling agent are provided. Lecithin and ascorbic acid or an ascorbic acid derivative act as an organogelling agent to form reverse worm-like micelles of a variety of oils. A thickened gel composition having a reverse worm-like micelle structure can be prepared with a ternary system of lecithin, ascorbic acid or an ascorbic acid derivative, and a variety of oils.
    Type: Application
    Filed: November 30, 2012
    Publication date: December 18, 2014
    Inventors: Kaname Hashizaki, Yoshihiro Saito, Hiroyuki Taguchi
  • Publication number: 20140370081
    Abstract: The invention relates to enantiomerically pure DOTAP chloride and stable crystal modifications of (2R,S)-, (25)- and (2R)-DOTAP chloride, to a process for the preparation of these modifications, and to the use thereof as constituent for the preparation of medicaments.
    Type: Application
    Filed: September 2, 2014
    Publication date: December 18, 2014
    Applicant: Merck Patent GmbH
    Inventors: Michael Platscher, Alfred Hedinger
  • Publication number: 20140357731
    Abstract: A method for formulating a cationic and non-ionic oil in water emulsion, preferably in a cream form, containing growth factors, preferably platelet derived growth factors, specific matrikine peptides, botanicals, emollients, nano-molecules, antioxidants, antiseptics, neuro-peptides, anti-dermatophytics, polysaccharides, sensorial peptides, osmotically driven moisturizers, and siloxane barriers. For application to the feet and other affected parts of the body for the relief of diabetic skin and tissue trauma.
    Type: Application
    Filed: June 3, 2014
    Publication date: December 4, 2014
    Inventor: ALVIN DAVID NEEDLEMAN
  • Publication number: 20140357600
    Abstract: Described herein are compositions (e.g., a pharmaceutical composition) and methods for controlling the delivery of a therapeutic agent, and their use in the treatment and/or prevention of diseases and disorders.
    Type: Application
    Filed: June 6, 2014
    Publication date: December 4, 2014
    Applicant: CHEMIC LABORATORIES INC.
    Inventors: Joseph P. St. Laurent, Scott A. Goodrich, Gerald S. Jones, Jr.
  • Patent number: 8900603
    Abstract: The invention relates to oligofluorinated coatings and their use in drag delivery The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: December 2, 2014
    Assignee: Interface Biologics, Inc.
    Inventors: Roseita Esfand, J. Paul Santerre, Sylvia Tjahyadi, Bernadette Ilagan
  • Patent number: 8901347
    Abstract: Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applications, tissue adhesives products, implantable medical devices, foams and reticulated foams for wound healing and drug delivery, bone hemostats and bone void fillers, adhesion prevention barriers, meshes, filters, stents, medical device coatings, pharmaceutical drug formulations, consumer product and cosmetic and pharmaceutical packaging, apparel, infusion devices, blood collection tubes and devices, other medical tubes, skin care products, and transdermal drug delivery materials.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: December 2, 2014
    Assignee: Bezwada Biomedical, LLC
    Inventor: Rao S. Bezwada
  • Publication number: 20140348767
    Abstract: Provided is a compound capable of gelling various aqueous compositions containing salt, acid and the like. An amphoteric ion-type basic amino acid derivative represented by the formula (1A): wherein each substituent is as defined in DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: August 6, 2014
    Publication date: November 27, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenji HANABUSA, Masahiro SUZUKI, Takanori SUGIMOTO
  • Publication number: 20140343171
    Abstract: Compositions comprising isosorbide monoesters and hydroxypyridones What are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more substances selected from the group consisting of hydroxypyridones and their salts. The compositions are distinguished in particular by an advantageous antimicrobial activity.
    Type: Application
    Filed: July 31, 2012
    Publication date: November 20, 2014
    Applicant: CLARIANT INTERNATIONAL LTD.
    Inventors: Maurice Frederic Pilz, Peter Klug, Franz-Xaver Scherl, Joerg Grohmann
  • Patent number: 8889189
    Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Phares Pharmaceutical Research, N.V.
    Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton