Abstract: The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one anionic surfactant selected from the group including phosphoric acid fatty esters and oxyethylenated derivatives thereof, and mixtures thereof; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion, and methods for its use. The nanoemulsion is ideally transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in compositions, including topical, pharmaceutical, dermatological, cosmetic, opthalmic, and opthalmologic.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked ureas or carbamates of heterocyclic thioesters.

Abstract: A composition and method for retarding or preventing hair growth, wherein the composition includes a) citric acid, b) an electrolyte, and c) a cosmetically acceptable aqueous vehicle which includes a film forming agent.

Abstract: Formulations for the prevention and therapy of hair loss and seborrhoea are based on essential oils obtainable through alcoholic distillation of plants which contain the essential oils, combined with salicylic acid and with fatty acids having 10 to 40 carbon atoms.

Abstract: There is provided a cosmetic composition having at least two film formers and a plasticizer in a water-in-solvent emulsion. The film formers are (1) alkyl cycloalkylacrylate copolymers having C14 to C36 alkyl repeating units, and (2) esters containing acids derived from rosin. The plasticizer is preferably a block copolymer. The composition is transfer and wear resistant and maintains a high shine.

Abstract: Methods and compositions for stimulating the growth of hair are disclosed containing prostaglandins, derivatives or analogues thereof for use in treating the skin or scalp of a human or non-human animal. Prostaglandins of the A2, F2&agr; and E2 types are preferred for this treatment method.

Abstract: A germicidal composition suitable for cleaning fruits, vegetables, skin and hair, includes a mixture of fruit acids and a surfactant. The surfactant may be an anionic surfactant (such as sodium lauryl sulfate), a sophorose lipid biosurfactant, or a combination of the two surfactants. The mixture of fruit acids may include citric acid, glycollic acid, lactic acid, malic acid and tartaric acid. The fruit acids are preferably present, in an aqueous solution, in a sufficient amount to produce a pH of about 2-6, for example 3.8-4.2. The compositions of the present invention are germicidal, and are sufficient to kill 100% of E. coli, Salmonella and Shigelia in 30 seconds after application to the surface of the object.

Abstract: A sustained hair growth preparation comprising minoxidil and dipropylene glycol makes it possible to retain the absorbed minoxidil in the dermis and to increase the concentration of the minoxidil around the hair bulbs which are the hair growing sites, thereby making it possible to give a sufficient hair growth effect.

Abstract: The present invention relates to hair treatment compositions and methods of manufacturing the compositions, which are capable of acting as a cosmetic, reducing alopecia, preventing alopecia, stimulating hair growth or any combination thereof. The hair treatment composition comprises loess juice, brown algae juice, artemisia juice, pine leaves juice, and additives.

Abstract: The invention encompasses compounds corresponding to the formula in which R1 denotes a C1-C31, preferably C9-C25, hydrocarbon-comprising radical, in particular a saturated or unsaturated, linear or branched, C1-C31, preferably C9-C25, alkyl radical which can be substituted by one or more optionally esterified hydroxyls; and OR2 denotes a cholesteryl radical; the said compounds being in the form of a pure enantiomer or in the form of a mixture of isomers. The invention also relates to their process of preparation and to their use, in particular for the treatment and care of the skin, hair, nails and eyelashes, in cosmetics or in dermatology.

Abstract: This invention relates to methods of treating hair loss, through hair revitalization and germination, by administering non-immunosuppresive pyrrolidine carboxylate and pyrrolidine amide compounds.

Abstract: Compositions containing depolymerized fucane sulphates characterized by the following parameters (percentages by weight on the dry product): Molecular weight: 5,000-30,000 dalton; Sulphur: 5-16%; Fucose: 25-60%; Uronic acids 2-25%; they increase the percentage of growing hair and inhibit the Pytirosporun growth on the skin.

Abstract: A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a suppressor of the metabolic pathway for the conversion of glucose to acetyl-CoA.

Abstract: Hydroxypropyl quaternary ammonium compounds containing an ester function, in particular containing a fatty acid ester function, of formula (I): in which R denotes a branched C7-C35 alkyl chain; R1, R2 and R3 independently denote a C1-C18 alkyl chain; X− denotes a halide or another anion chosen from: in which R4 and R5 independently denote a C1-C8 alkyl chain are disclosed. Cosmetic or dermatological compositions containing these compounds, in particular haircare products in which the quaternary compounds are used as treatment agents for improving the surface condition of the hair as well as for protecting the hair under the action of atmospheric agents or mechanical or chemical treatments are disclosed.

Abstract: The present application relates to novel ceramide compounds to their process of preparation and to their use in cosmetics or in pharmaceuticals, in particular for treating and caring for the skin, hair, nails and eyelashes.

Abstract: The invention concerns the use of a substance P antagonist in a cosmetic composition used to treat sensitive skin. More specifically, the invention relates to a substance P antagonist used to prevent and/or combat skin irritations, desquamation, erythemas, sensations of dysesthesia/overheating, or pruritus of the skin.

Abstract: A method of enhancing hair growth or treating alopecia in a subject uses topically administered estrogen receptor antagonists. Pharmaceutical formulations comprising estrogen receptor antagonists are described.

Abstract: Methods and compositions for promoting hair growth, preventing or minimizing hair loss, enhancing or restoring hair color or remelanization and treating other hair and skin conditions are disclosed. The methods include topical application of the compositions to the skin or hair follicles being treated. The compositions include as an essential component a treatment agent in an amount effective for treating the condition and selected from the class of compounds consisting of anole, anethole, analogs thereof, polymers thereof and mixtures thereof. Various combinations of these compounds may be found in herb families including umbelliferae, magnoliaceae, labiatae and rutaceae. The invention preferably contemplates selecting the treatment agent from the class of herbs consisting of Foeniculum vulgares (fennel seed), Pimpinella anisum (anise), Carum carvi (caraway seeds) and mixtures thereof with each other and/or other herbs.

Abstract: A hair growth stimulant comprising p-menthane-3,8-diol and at least one substance from the group of a blood circulation promoter, a 5&agr;-reductase inhibitor, an antihistaminic, a cell activator, an antiphlogistic and an antimicrobial is disclosed. The hair growth stimulant is free from hormonal action, does not cause side effects and has excellent hair growth promoting effects.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.

Abstract: The present invention includes methods for the treatment and/or prevention of hair loss and methods for the regeneration or restoration of hair growth comprising a step of identifying an individual suffering from or susceptible to hair loss or hair thinning or in need of hair regeneration, and a step of administering an extract of the root of a Vetiver grass. Preferably, the extract is an aqueous extract and is administered topically. Also preferably, the Vetiver grass is a subspecies of Vetiveria zizanioides, and is most preferably Vetiveria zizanioides (L.) Nash. The present invention also provides a composition, preferably in the from of a lotion, gel, cream, or other suspension, and a distinct chemical compound or class of chemical compounds therein, effective in restoring hair growth, preventing hair loss, and/or reversing the effects of hair thinning.

Abstract: A composition for cosmetics use which comprises a lysophospholipid mixture, wherein 30 mol % or more of fatty acids bonded to said lysophospholipid mixture are monoenoic fatty acids; and a cosmetic composition which comprises a lysophospholipid mixture and a cosmetically acceptable carrier, wherein 30 mol % or more of fatty acids bonded to said lysophospholipid mixture are monoenoic fatty acids. The cosmetic composition having such a lysophospholipid mixture has high storage stability and is excellent in feeling upon use.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.

Abstract: An aqueous hair conditioning composition is disclosed. The composition includes stearalkonium chloride and a stabilizing component comprising a polyoxyethylene glycol ether of stearyl alcohol, such as, for example, polyoxyethylene (21) stearyl ether. The polyoxyethylene stearyl ether is provided in an amount sufficient to inhibit precipitation of stearalkonium chloride in the composition. Also disclosed are a method of conditioning hair and a method of inhibiting precipitation of a stearalkonium chloride in an aqueous cosmetic hair conditioning composition.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule sulfonamides.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.

Abstract: Topically applicable hair growth-/hair loss-affecting cosmetic/pharmaceutical compositions for treating mammalian subjects with hair or scalp disorders, comprise an effective amount of at least one 2-amino-1,3-alkanediol compound having the structural formula (I): formulated into a physiologically topically acceptable carrier medium therefor.

Abstract: A compound effect for the treatment of dermatological disorders comprises a mono- or diester of an &agr;,&ohgr;-dicarboxylic acid, wherein the alcohol moiety of the said ester comprises a keratolytically active alcohol. The compound may have the formula, where n is in the range of 6 to 12; m is in the range of 0 to 8; R′ is selected from the group consisting of H, alkyl, aryl, alkenyl, benzyl, OH, NHR″, CONHR″ and COOR″; R″ is selected from the group consisting of alkyl, aryl, alkenyl, and benzyl; and Y is selected from the group consisting of H, alkyl, aryl, alkenyl, benzyl and X.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pyrrolidine derivatives.

Abstract: Disclosed is a hair revitalizing tonic composition containing a dimethylpropanediol derivative of the formula: wherein R1 and R2 are each independently a C1-30 hydrocarbon group which may be substituted, or a five- or six-membered heterocyclic group which contains 1 to 4 heteroatoms selected from oxygen, sulfur and nitrogen atoms and which may be substituted, R3 is hydrogen atom, an alkyl group which may be substituted, an acyl group, an alkoxycarbonyl group, a phenoxycarbonyl group, or a carbamoyl group which may be substituted, and a and b are each 0 or 1, as well as a method for effecting hair growth promotion, hair growth stimulation, or hair loss prevention in mammals by using such a hair revitalizing tonic composition. Also disclosed is the use of a compound of formula (I) in the preparation of a hair revitalizing tonic composition. Thus, this invention can provide an excellent means of hair revitalization or hair loss prevention in mammals.

Abstract: A cosmetic or pharmaceutical composition for the treatment of the hair and scalp contains nonionic lipids capable of forming a lipidic lamellar phase in combination with an aqueous solution containing at least one cationic surface active agent and/or a quaternized protein.

Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-oxides of heterocyclic esters, amides, thioesters, or ketones.

Abstract: The present invention concerns a method for modulating hair by affecting the hedgehog protein signal transduction pathway. In one aspect, the invention provides a method for promoting hair or attenuating hair loss by stimulating the hedgehog protein signal transduction pathway. In a second aspect, the invention provides a method of retarding hair growth or promoting hair loss by antagonizing the hedgehog protein signal transduction pathway. The method can also be used to control hair pigmentation.

Abstract: A hair growth formulation. The two basic main ingredients are castor oil and a special lemon extract. The special lemon extract is made from fresh lemon peel. The peel, including the bioflavonoids membrane, is blended with purified water until it is liquidified. Then the mixture is filtered through a sanitized cloth. Other ingredients that have been found helpful include: inositol, choline (from bitartate), niacinamide or nicotinic acid, manganese in chelated form, bioflavonoids, and folic acid. Finally perfume and sodium benzoate (as a preservative) can be added.

Abstract: The character of male beard hair growth is altered by employing a conventional shave enhancing composition containing a topically active chemical agent capable of acting upon the sites influencing beard hair growth.

Abstract: Hair conditioning compositions comprising 0.1-20% cationic conditioning agent, 0.1-30% fatty alcohol, 0.001-10% nonionic surfactant, 0.001-20% of a polysiloxane having D and T units, wherein the ratio of D units to T units in the polysiloxane is about 10 to 80 D units for every T unit; and 5-95% water; as well as a method for improving the fade resistance of color treated hair comprising applying to the hair an aqueous based hair care composition containing one or more hair treating active ingredients and a siloxane having D and T units, wherein the ratio of D units to T units in the siloxane is about 10 to 80 D units for every T unit.

Abstract: A hair growth phase extender containing, as an effective ingredient, at least one compound selected from the group consisting of unsaturated fatty acid and/or its derivatives, especially an unsaturated fatty acid having the formula:C.sub.n H.sub.m O.sub.2where n is 12 to 28 and m is n+1 to 2n-2; or containing, as an effective ingredient, an extract of a plant belonging to the Coriandrum.

Abstract: Pesticides for the extermination of terrestrial arthropods are disclosed which comprise formulations of a combination of terpenes in aqueous solutions which may be used together with citral. No resistance to the formulations of the invention has been seen. When used on the scalp or body for lice infestation no extended dwell time is required. The formulations do not have unpleasant odors. The formulations are directed towards providing topical preparations which may be used on the skin, scalp and hairy body parts of humans and animals, sprays for use directly against terrestrial arthropods, a dipping solution for combs and a laundry additive, amongst others.

Abstract: A fine and stable emulsion of an oily phase in an aqueous phase containing ionic polymer particles, the oil globules of the emulsion having a mean size of at most 500 nm, a process for the stabilization of fluid emulsions, a process for the preparation of these emulsions and their use in the cosmetic and dermatological fields and more particularly as composition for anti-sun protection.

Abstract: A hair-growing agent comprising proanthocyanidin as the active ingredient. The present invention provides a hair-growing agent having strong pharmaceutical effects.

Abstract: An inhibitor of cholesterol synthesis is used for the treatment, alleviation or prevention of skin disorders.

Abstract: A hair cosmetic composition comprising an amine-oxide-containing water-soluble resin having a weight-average molecular weight of 5,000 to 1,000,000. The hair cosmetic composition of the present invention has excellent setting force, conditioning effects and hair-washing property and being free from stickiness.

Abstract: Dermatological/cosmetic compositions for reducing or decelerating human hair loss comprise an effective hair loss-reducing amount of combinatory immixture of (a) at least one antifungal agent and (b) at least one halogenated antibacterial agent other than a macrolide or pyranoside, characteristically formulated in a topically physiologically acceptable medium therefor.

Abstract: The invention concerns a procedure for testing a potentially-active substance used in the hair-care field, this procedure being characterized by the fact that a fragment of at least one hair follicle without dermal papilla is isolated, this fragment being taken from beneath the point of attachment of the sebaceous gland and excluding the portion of the hair shaft located above the point of attachment of the sebaceous gland; that this fragment is incubated in a suitable culture medium for a sufficient period; that this fragment is placed in contact with a potentially-active hair-care substance; that a marker of the activity of said tested substance is quantitatively determined; and that the results of this determination are assessed as they compare to a control.

Abstract: Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsifying agent, advantageously an anionic amphiphilic polymer, and (c) at least one biologically active agent, for example an active agent that modulates skin differentiation and/or proliferation and/or pigmentation, an anti-inflammatory, an antibacterial, an antifungal, etc.

Abstract: A dispersion for carrying at least one water-soluble material or water-dispersible material (especially ascorbic acid, Vitamin C) in a relatively stable form is described, the dispersion comprising an oil phase containing particles comprising water-soluble polymer, water-soluble material or water-dispersible material (ascorbic acid), and water. The dispersion preferably comprises particles which have number average diameter dimensions of less than 2 microns, more preferably less than 1 micron. The dispersion may comprise oil components such as, for example only, a mineral oil, silicone oil, or cosmetic oil. A method of forming a dispersion of solid particles which comprise water-soluble material or water-dispersible material (e.g.

Abstract: A method for maintaining hair growth and coloration in humans by using neurotrophin ligands to prevent p75 nerve growth factor (NGF) receptor mediated apoptosis in melanocytes and keratinocytes is described.

Abstract: A method of inhibiting hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a non-steroidal suppressor of angiogenesis.

Abstract: Seborrheic dermatitis of the scalp is treated by a synergistic combination of a cytotoxic agent and an antifungal agent.