Hair Treatment (therapeutic-scalp) Patents (Class 514/880)
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Patent number: 5281610Abstract: Disclosed is a pyrazolonaphthyridine compound represented by the formula: ##STR1## wherein R.sup.1 is represents hydrogen, lower alkyl, aralkyl, or substituted or unsubstituted aryl, R.sup.2 represents hydrogen, lower alkyl, thienyl, substituted or unsubsutituted aryl, hydroxy or amino, or a pharmaceutically acceptable salt thereof.The compound possesses antiinflammatory effect, immunosuppressive effect, broncho-dilatory effect and hair growth-stimulative effect.Type: GrantFiled: December 18, 1992Date of Patent: January 25, 1994Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Fumio Suzuki, Takashi Kawakita, Takeshi Kuroda, Kenji Ohmori, Hiroshi Nakajima, Toshikazu Kamiya, Tatsuya Tamaoki
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Patent number: 5280018Abstract: A topical pharmaceutical formulation, useful as a vehicle for E-type prostaglandins and in the treatment of androgenetic alopecia, is described.Type: GrantFiled: July 10, 1989Date of Patent: January 18, 1994Assignee: American Cyanamid CompanyInventors: Lawrence Ritter, James R. Lawter
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Patent number: 5258391Abstract: Therapeutic as well as preventative measures to improve the cosmetic conditions or to alleviate the symptoms of dermatologic disorders with phenyl alpha acyloxyalkanoic acids and derivatives is disclosed. The cosmetic conditions and dermatologic disorders in humans in which the compounds may be useful include brittle or soft nails; abnormally thin skin, mucous membranes or wound; friction blisters; brittle hairs; pruritus; acne; and diseased nails, skin or mucous membranes due to natural or unnatural causes including but not limited to in flammations or infections. The phenyl alpha acyloxyalkanoic acids and derivatives include, for example, diphenyl alpha acetoxyacetic acid, phenyl alpha acetoxyacetic acid, phenyl alpha methyl alpha acetoxyacetic acid and phenyl alpha acetoxypropanoic acid. The compositions containing the active ingredients are also useful for treatment of skin, nails and hair conditions or disorders in domestic animals.Type: GrantFiled: December 20, 1990Date of Patent: November 2, 1993Inventors: Eugene J. Van Scott, Ruey J. Yu
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Patent number: 5256647Abstract: This invention provides compositions comprising a physiologically-active agent and a compound having the structural formula ##STR1## wherein X may represent sulfur or two hydrogen atoms; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n is 0-18 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen, in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.Type: GrantFiled: November 13, 1990Date of Patent: October 26, 1993Assignee: Whitby Research, Inc.Inventors: Gevork Minaskanian, James V. Peck, Eric L. Nelson
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Patent number: 5256403Abstract: Solubilized melanin based compositions supply melanin to skin, scalp and/or hair. The compositions consist of melanin, as an active ingredient, and a substance to solubilize the melanin blended together in a vehicle suitable for topical application. A melanin-based composition applied to the skin provides photoprotection of the human epidermis from exposure to ultraviolet rays. A melanin-based composition applied to wounds in the skin accelerates healing of the wounds. A melanin-based composition applied to the hair and scalp strengthens the hair.Type: GrantFiled: January 8, 1991Date of Patent: October 26, 1993Inventor: Frances C. Gaskin
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Patent number: 5217711Abstract: In a composition for enhancing the growth of hair comprising a conditioner having the following ingredients based on a total of 500 grams by weight:______________________________________ water approximately 435.5 gm. cetyl alcohol approximately 12.5 gm. standamul approximately 12.5 gm. proteins approximately 35.0 gm. citric acid approximately 2.5 gm. honey approximately 0.5 gm. wheat germ oil approximately 0.5 gm. lecithin approximately 0.5 gm. herbal extract approximately 0.5 gm. methylchloroisothiazolinone approximately 0.5 gm. ______________________________________The composition also includes a shampoo and a cleansing solution.Type: GrantFiled: October 16, 1991Date of Patent: June 8, 1993Inventor: Mariana De Oliveira
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Patent number: 5216033Abstract: A water-in-silicone oil transparent emulsion is made from a volatile polydimethylsiloxane (1 to 50% by weight), a silicone surfactant (0.1 to 20% by weight), at least one polyhydric alcohol (1 to 50% by weight) and water.The silicone surfactant comprises a polymer of dimethyl polysiloxane with polyoxyethylene and/or polyoxypropylene side chains having a molecular weight of from 10,000 to 50,000 and having the structure: ##STR1## a having a value of from 9 to 115, b having a value of from 0 to 50,x having a value of from 133 to 673,y having a value of from 25 to 0.25.Type: GrantFiled: June 28, 1990Date of Patent: June 1, 1993Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.Inventors: Mavis C. Pereira, Udo Spiegel
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Patent number: 5215760Abstract: Composition in the form of a solution for inducing and stimulating hair-growth and for decreasing hair loss, said solution is a 100% saturation of purified sodium chloride fully dissolved in purified Aloe Vera.Type: GrantFiled: May 12, 1992Date of Patent: June 1, 1993Inventors: Howard Kavoussi, Harold P. Kavoussi
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Patent number: 5208015Abstract: The certain imidazoles have been found to exhibit anti-inflammatory as well as antifungal activity.Type: GrantFiled: July 23, 1991Date of Patent: May 4, 1993Assignee: Bristol-Myers Squibb CompanyInventors: Hemanshu S. Shah, Cheng-Der Yu, John Gibson
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Patent number: 5204092Abstract: A cosmetic composition comprises in solution in an appropriate vehicle at least one polymer having 50-100% of repeating units of the .beta.-alanine type having the formula ##STR1## and 0-50% of repeating units of the acrylamide type having the formula ##STR2## wherein R.sub.1 represents hydrogen or a member selected fromthe group consisting of (i) ##STR3## (ii) --CH.sub.2 OH, (iii) --(CH.sub.2).sub.n --CH.sub.3 wherein n is 0 or a whole number from1 to 11, (iv) ##STR4## wherein r' and r" each independently represent hydrogen or alkyl having 1-3 carbon atoms, (v) --CHOH--COOH, (vi) --CH.sub.2 --SO.sub.3 Na,(vii) ##STR5## and (viii) --(CH.sub.2 --CH.sub.2 --O).sub.m H wherein m ranges from 1 to 10, and R.sub.2 and R.sub.3 represent hydrogen or methyl.Type: GrantFiled: June 30, 1982Date of Patent: April 20, 1993Assignee: Societe Anonyme dite: L'orealInventors: Claude Mahieu, Christos Papantoniou
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Patent number: 5198470Abstract: The invention relates to a lipid compound of formula (I): ##STR1## where R.sub.1 denotes a C.sub.11 to C.sub.21 alkyl or alkenyl radical and R.sub.2 denotes a linear or branched C.sub.8 to C.sub.30 hydrocarbon radical, saturated or bearing one or more ethylenically unsaturated bonds, and also to a process for preparing it and to compositions for cosmetic use or pharmaceutical use for skin conditions containing this compound.Type: GrantFiled: June 25, 1992Date of Patent: March 30, 1993Assignee: L'OrealInventors: Alexandre Zysman, Guy Vanlerberghe, Henri Sebag
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Patent number: 5194250Abstract: A skin- or hair-care composition containing silica additionally comprises a C.sub.2-4 alkyl ester of a di, tri- or tetrabasic carboxylic acid or hydroxy-carboxylic acid (optionally acetylated). The alkyl ester may be dissolved in an aqueous solvent system.Type: GrantFiled: June 26, 1991Date of Patent: March 16, 1993Assignee: Beecham Group p.l.c.Inventors: Edgar Fairhurst, Helen Sayers, Steven Poile
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Patent number: 5194252Abstract: A novel composition of a hydrolyzed protein together with a surfactant produces a proteinaceous film on the skin to retard moisture loss in cosmetic and toiletry products, such as after shaves, and cleansing lotions. The products retard moisture loss from the skin matrix, but the primary cleansing functions of the products, i.e., removing excess moisture and oil, are not inhibited.Type: GrantFiled: December 31, 1991Date of Patent: March 16, 1993Assignee: ViJon Laboratories, Inc.Inventor: William H. Hofmann
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Patent number: 5192544Abstract: Cosmetic or pharmaceutical composition consisting of a dispersion in a physiologically acceptable aqueous phase D of vesicles of ionic and/or nonionic amphiphilic lipid(s), the vesicles being bounded by one or more lipid lamellae, the lipid lamellae containing at least one retinoid compound and the aqueous dispersion phase a pyrimidine derivative. The said composition may be used by topical application on the hair and scalp.Type: GrantFiled: October 11, 1990Date of Patent: March 9, 1993Assignee: L'OrealInventors: Jean-Francois Grollier, Georges Rosenbaum, Isabelle Richoux
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Patent number: 5192769Abstract: Disclosed is a pyrazolonaphthyridine compound represented by the formula: ##STR1## wherein R.sup.1 is represents hydrogen, lower alkyl, aralkyl, or substituted or unsubstituted aryl, R.sup.2 represents hydrogen, lower alkyl, thienyl, substituted or unsubstituted aryl, hydroxy or amino, or a pharmaceutically acceptable salt thereof.The compound possesses antiinflammatory effect, immunosuppressive effect, broncho-dilatory effect and hair growth-stimulative effect.Type: GrantFiled: July 30, 1992Date of Patent: March 9, 1993Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Fumio Suzuki, Takashi Kawakita, Takeshi Kuroda, Kenji Ohmori, Hiroshi Nakajima, Toshikazu Kamiya, Tatsuya Tamaoki
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Patent number: 5190916Abstract: A treating agent such as a wound therapeutic agent, inflammation therapeutic agent, hair growth agent and hair tonic, and a cosmetic, comprising as an effective component ovomacroglobulin are disclosed. They can act on the skin, a scalp or hairs to exhibit excellent wound curing promotion effect, hair growth promotion effect, and skin or hair protective effect.Type: GrantFiled: February 8, 1988Date of Patent: March 2, 1993Assignees: Japan Immuno Research Laboratories Co., Ltd., Otsuka Pharmaceutical Co., Ltd.Inventor: Masakazu Adachi
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Patent number: 5185325Abstract: A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises a glycosaminoglycanase inhibitor chosen from aldonomonolactones, alduronomonolactones and acylated monosaccharides, and a cosmetically acceptable vehicle for the inhibitor; the total amount of the inhibitor present in the composition being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than 3 months, by at least 10% more than that obtainable using a control composition from which the said inhibitor has been omitted, in accordance with the Rat Hair Growth Test.Type: GrantFiled: November 20, 1991Date of Patent: February 9, 1993Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.Inventors: Peter R. Brawn, Walter T. Gibson
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Patent number: 5183817Abstract: Increase in the rate of hair growth, stimulation of hair follicles to produce new hair growth, prolongation of the anagen phase of the hair cycle, conversion of vellus hair to growth as terminal hair, and treatment of alopecias due to organic dysfunction of the hair follicle is attained in mammalian skins by either oral administration or by topical application to the skin, hair and/or hair follicles of the mammal of effective amounts of a retinoid, particularly retinoic acid, and a minoxidil-type compound. The combination may be administered or applied alone or with other adjunctive compounds including vitamins, such as Vitamin D.sub.3, hormones, and/or antiandrogens.Type: GrantFiled: December 13, 1988Date of Patent: February 2, 1993Inventor: Gail S. Bazzano
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Patent number: 5182407Abstract: The present invention relates to the compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, denote a methyl or ethyl radical;R.sub.3 denotes a methyl, ethyl or hydroxyethyl radical;A denotes a ##STR2## radical or ##STR3## R denotes H or CH.sub.3 ; X denotes Cl.sup.-, BR.sup.-, I.sup.-, CH.sub.3 OSO.sub.3.sup.-, CH.sub.3 SO.sub.3.sup.-, ##STR4## p and q, which are identical or different, denote integers such that 1.ltoreq.p.ltoreq.15, 0.ltoreq.q.ltoreq.13 and 2.ltoreq.p+q.ltoreq.20;n denotes an integer equal to 2 or 3;m denotes 0 or 1, and m+q.noteq.0;as well as the salts from neutralization by bases, their preparation process and their utilization as an additive in compositions for treatment of keratinous materials.Type: GrantFiled: July 17, 1991Date of Patent: January 26, 1993Assignee: L'OrealInventor: Henri Sebag
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Patent number: 5182269Abstract: Depolymerized deoxyribonucleic acid containing weight amounts of purine and pyrimidine bases such that the related molar ratio purinea/pyrimidines is comprised within a determined range and having moreover molecular weights limited to a determined range of values of less than 100,000 are endowed with remarkable hair stimulating activity.Type: GrantFiled: February 11, 1991Date of Patent: January 26, 1993Assignee: Crinos Industria Farmacobiologica SpAInventor: Giovanni Gazzani
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Patent number: 5175340Abstract: The invention relates to an unsaturated benzalmalonate derivative of formula: ##STR1## in which: R.sub.1 and R.sub.2 denote a hydrogen atom, a hydroxyl, a trimethylsiloxy, a C.sub.1 -C.sub.6 straight or branched chain alkyl, C.sub.1 -C.sub.6 straight or branched chain alkoxy or a --(CH.sub.2).sub.p --C(R.sub.4).dbd.CH.sub.2 radical, where p is an integer between 1 and 10 and preferably between 1 and 4 and R.sub.4 denotes a hydrogen atom or a C.sub.1 -C.sub.4 straight or branched chain alkyl radical, one of the two radicals R.sub.1 or R.sub.2 denoting a residue --(CH.sub.2).sub.p --C(R.sub.4).dbd.CH.sub.2,R.sub.3 denotes a hydrogen atom, a C.sub.1 -C.sub.6 straight or branched chain alkyl radical or a C.sub.1 -C.sub.6 straight or branched chain alkoxy radical,R.sub.5 and R.sub.6, which are identical or different, denote a C.sub.1 -C.sub.8 straight or branched chain alkyl radical.Use as a sunscreen in cosmetic compositions.Type: GrantFiled: July 5, 1989Date of Patent: December 29, 1992Assignee: L'OrealInventors: Serge Forestier, Gerard Lang, Herve Richard
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Patent number: 5173289Abstract: Aromatic esters and thioesters of the formula ##STR1## are useful in human and veterinary medicine and in cosmetic formulations. In the formula, X represents oxygen or sulfur, r' and 4" represent hydrogen, lower alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl optionally substituted, the residue of an amino acid or aminated sugar, or taken together form a heterocycle, R.sub.2 represents .alpha., .alpha.'- dissubstituted alkyl having 4-12 carbon atoms or mono- or polycyclic cycloalkyl having 5-12 carbon atoms whose carbon linking carbon is trisubstituted and R.sub.3 and R.sub.4 represent hydrogen or lower alkyl.Type: GrantFiled: February 16, 1990Date of Patent: December 22, 1992Assignee: Centre International de Recherches Dermatologiques (C.I.R.D.)Inventors: Braham Shroot, Jacques Eustache, Jean-Michel Bernardon
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Patent number: 5158955Abstract: A preserved composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises:(i) a special ester of pyroglutamic acid; and(ii) a cosmetically acceptable vehicle for the ester.Type: GrantFiled: December 10, 1991Date of Patent: October 27, 1992Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.Inventors: Walter T. Gibson, Ian R. Scott
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Patent number: 5157036Abstract: The subject of the invention is a new composition comprising a nicotinic ester with a pyrimidine derivative, to produce hair regrowth much more rapidly than with the pyrimidine derivative alone, the nicotinic ester for its part having no action in respect of hair regrowth. Furthermore, the combination makes it possible to use smaller quantities of pyrimidine derivatives or a lower frequency of application.Type: GrantFiled: October 31, 1990Date of Patent: October 20, 1992Assignee: L'OrealInventor: Jean F. Grollier
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Patent number: 5154919Abstract: A disposable depilatory composition including an elastomer, a resin and a softener or sweetener. This composition can be deposited on the skin in a thin layer and can be stripped from the skin without use of a film such as cellophane.Type: GrantFiled: October 17, 1991Date of Patent: October 13, 1992Inventor: Christian Des Garets
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Patent number: 5152990Abstract: A hair grower consisting of each extract from the skin of a navel orange, the skin of an iyokan (Citrus iyo), the skin of a hassaku (Citrus hassaku), the skin of a sweet summer orange, the skin of a lemon, the skin of a mandarin orange, an aloe, all of said extracts are prepared by extracting with sake. The hair grower has an exellent hair-growing effect to positively promote the growth of human hair.Type: GrantFiled: January 23, 1991Date of Patent: October 6, 1992Inventor: Yutaka Miyauchi
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Patent number: 5151436Abstract: Therapeutically useful thioformamide derivatives of the formula: ##STR1## wherein R represents alkyl, Het represents pyrid-3-yl, isoquinolin-4-yl, tetrahydroquinolin-3-yl, quinolin-3-yl, pyridazin-4-yl, pyrimid-5-yl, thiazol-5-yl, thieno[2,3-b]-pyridin-5-yl, pyrazin-2-yl, indol-3-yl and thieno[3,2-b]-pyridin-6-yl, Y represents ethylene, methylene or a valency bond, and X represents carbonyl, hydroxymethylene, >C.dbd.NOR.sup.1, >C.dbd.NN(R.sup.1).sub.2 or >C.dbd.NN(R.sup.1)CON(R.sup.1).sub.2 in which R.sup.1 represents hydrogen or optionally substituted alkyl, benzyl, phenethyl, 1-naphthylmethyl, 2-naphthylmethyl or pyrid-3-ylmethyl, or two R.sup.1 substituents on the same nitrogen atom may together form an optionally substituted alkylene radical chain and salts thereof, processes for their preparation and compositions containing them are described.Type: GrantFiled: August 23, 1990Date of Patent: September 29, 1992Assignee: Rhone-Poulenc SanteInventors: David C. Cook, Terance W. Hart, Iain M. Mc Lay, Malcolm N. Palfreyman, Brian W. Sharp, Roger J. A. Walsh
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Patent number: 5130142Abstract: The present invention relates to a composition for regulating hair growth comprising a safe and effective amount of a supernatant derived from a culture of epithelial cells which comprises a growth stimulating factor with characteristics of mitogenicity to dermal papilla cells, mitogenicity to 3T3 cells, lack of mitogenicity to epidermal cells, and a molecular weight of greater than about 3,000D; and a pharmaceutically-acceptable carrier.Type: GrantFiled: October 31, 1990Date of Patent: July 14, 1992Assignee: The Practer & Gamble CompanyInventors: Teresa K. Wong, Raphael Warren
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Patent number: 5126125Abstract: A method of decreasing the melanin content in mammalian skin and hair by administering to a mammal a composition comprising an effective amount of one or more derivatives of 5,6-dihydroxyindole, the derivatives having one or more substituents which are capable of being removed enzymatically, in admixture with a pharmaceutically acceptable carrier, the amount being 0.5% to 20% wt/wt based on the composition.Type: GrantFiled: October 6, 1989Date of Patent: June 30, 1992Assignee: Yale UniversityInventor: John M. Pawelek
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Patent number: 5124446Abstract: Betaine group-containing polysaccharides with recurring anhydroglucose units of the average, general formula ##STR1## are disclosed. In this formula the R.sup.1 groups are the same or different and represent methyl, (C.sub.n H.sub.2n O).sub.m R.sup.2 or ##STR2## in which n=2 or 3, m=0 to 10, p=0 to 10 and R.sup.2 is a hydrogen atom or the betaine group ##STR3## in which R.sup.3 and R.sup.4 are the same or different and represent an alkyl group with 1 to 4 carbon atoms and R.sup.5 is a divalent aliphatic hydrocarbon group with 1 to 10 carbon atoms, with the proviso that at least 0.5% of the R.sup.1 groups in the polysaccharide molecule represent the betaine group.Also disclosed is a method for the synthesis of these compounds and their use in cosmetic preparations, especially for the care of the hair. In addition, novel compounds of the general formula ##STR4## are disclosed as intermediates in which the substituents R.sup.3, R.sup.4 and R.sup.5 have the above meaning.Type: GrantFiled: May 17, 1989Date of Patent: June 23, 1992Assignee: Th. Goldschmidt AGInventors: Burghard Gruning, Klaus Hoffmann, Gotz Koerner, Hans-Joachim Kollmeier
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Patent number: 5122369Abstract: An orally acceptable nutrient and mineral supplement for reducing hair loss wherein the composition contains divalent iron and pantothenic acid in a weight to weight ratio of approximately 1-3 and racemic d, 1-methionine. A particularly preferred composition contains 11.25 mg. of divalent iron as ferrous fumarate and 35 mg. of pantothenic acid as calcium pantothenate and 200 mg. of d,1-methionine.Type: GrantFiled: April 16, 1991Date of Patent: June 16, 1992Assignee: Harmony Health Products, Inc.Inventor: R. Harvey Dye
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Patent number: 5116606Abstract: Skin treatment solution and method having an aqueous, dissociable, sodium salt solution with a pH in the 6.0-8.0 range and containing enough sodium to substantially remove testosterone from the skin area to which the solution is applied topically. The sodium salt solution has sodium chloride as the major salt constituent and much smaller amounts of choline chloride, inositol, pantothenic acid and vitamin E, as well as a surfactant and sodium fluoride as a preservative.Type: GrantFiled: May 24, 1990Date of Patent: May 26, 1992Inventor: John P. Alt
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Patent number: 5116605Abstract: A topical application composition for mitigating male pattern baldness and testosterone-induced acne contains, as essential active, androgen-reducing components (a) a testosterone-reducing amount of an ionizable sodium salt, and (b) an association of compounds for forming, androgen segregating cellular proliferation phospholipids. The association includes lecithin, soy oil, phosphoric acid, choline chloride and optionally inositol and a nonionic surfactant in an amount for solubilizing and/or dispersing components (a) and (b) in a cosmetically-compatible vehicle for topical application.Type: GrantFiled: December 5, 1991Date of Patent: May 26, 1992Inventor: John P. Alt
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Patent number: 5106613Abstract: A hair conditioning shampoo is described, which contains C.sub.6, C.sub.8 and/or C.sub.10 alkyl sulfate and/or C.sub.6, C.sub.8 and/or C.sub.10 alkyl lower alkoxylate sulfate as an anionic detergent component, a water insoluble conditioning agent(s) from the group of silicones (preferably a certain type of aminosilicone), polyethylenes, paraffins, isoparaffins, microcrystalline waxes, C.sub.18-36(mixed) fatty acids or such triglycerides, high fatty alcohol ester of a high fatty acid (such as stearyl stearate), beeswax, cationic conditioning agent, such as a quaternary ammonium or any mixture thereof, and a stabilizer for the shampoo, in water. Among adjuvants that may be present are lauric monoethanolamide, cocodiethanolamide, and hydroxyethyl cellulose, other thickeners and viscosity modifiers, pH adjusting agents, antioxidants perfumes and colorants. The presence of the C.sub.6, C.sub.8 and/or C.sub.10 alkyl sulfate and/or C.sub.6, C.sub.8 and/or C.sub.Type: GrantFiled: January 14, 1991Date of Patent: April 21, 1992Assignee: Colgate-Palmolive CompanyInventors: Donna A. Hartnett, Charles Reich, Amrit M. Patel, Clarence R. Robbins
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Patent number: 5096697Abstract: Cell-stimulating composition having hair-growing effect and skin-vivifying effect. The composition comprising as an effective ingredient an aliphatic alcohol having odd number of carbon atoms or a derivative thereof in a cosmetically acceptable carrier.Type: GrantFiled: August 23, 1989Date of Patent: March 17, 1992Assignee: Lion CorporationInventors: Kuniaki Adachi, Hideo Tamai, Masanao Sadai
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Patent number: 5096911Abstract: The rate and character of mammalian hair growth is altered by the topical application to the skin of a composition containing an inhibitor of the enzyme gamma- glutamyl transpeptidase.Type: GrantFiled: June 25, 1990Date of Patent: March 17, 1992Inventors: Gurpreet S. Ahluwalia, Douglas Shander, F. Eugene Harrington
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Patent number: 5091173Abstract: A composition suitable for topical application to mammalian skin or hair comprising an amount of a cell-free supernatant from a culture of dermal papilla cells sufficient to increase hair growth in mammals.Type: GrantFiled: May 22, 1990Date of Patent: February 25, 1992Assignee: The University of DundeeInventors: Travis E. J. Buultjens, Stephen W. Hellens, Colin A. B. Jahoda, Roy F. Oliver, Anne P. Withers
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Patent number: 5086040Abstract: A dermatological hair growth stimulating composition containing an effective amount of a glycoprotein extract of gram negative bacteria as the growth stimulant and a method of stimulating hair growth.Type: GrantFiled: October 16, 1990Date of Patent: February 4, 1992Assignee: Roussel UclafInventors: Armelle Bonfils, Pierre Smets, Rene Zalisz
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Patent number: 5081151Abstract: A method for inducing, maintaining or increasing hair growth which is achieved by topically applying a preserved composition to mammalian skin and hair in a mammal having need thereof, the composition comprising a hexosaccharic acid, salts and esters thereof, in an amount sufficient to induce, maintain or increase hair growth.Type: GrantFiled: December 21, 1989Date of Patent: January 14, 1992Assignee: Chesebrough-Pond's USA Co., division of Conopco, Inc.Inventors: Michael F. A. Davis, Walter T. Gibson
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Patent number: 5071640Abstract: Non-ionic products of the formula:R--X--[C.sub.2 H.sub.3 (OCH.sub.2 CH.sub.2).sub.n(OH)--CH.sub.2 --Y--R'in which R and R' denote alkyl or alkenyl radicals having from 6 to 20 carbon atoms, the sum of the numbers of carbon atoms in R and R' being 24 to 32; X denotes an oxygen atom, a sulphur atom or a sulphoxide group; Y denotes a sulphur atom, a sulphoxide group or a methylene group (if Y denotes methylene, the sum of the numbers of carbon atoms in R and R' is 22 to 30); and n denotes an integer or decimal number from 1 to 40 are disclosed. These non-ionic compounds are suitable for use in pharmaceutical or cosmetic applications, in particular for the care of the skin or hair.Type: GrantFiled: February 6, 1989Date of Patent: December 10, 1991Assignee: Societe Anonyme dite: L'OrealInventors: Guy Vanlerberghe, Henri Sebag
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Patent number: 5069898Abstract: This invention provides a hair enrichment composition which includes a hair-sorbable bulking agent, a blood vessel dilator, and a scalp stimulant, together with a method of using the composition.Type: GrantFiled: April 24, 1989Date of Patent: December 3, 1991Assignee: Revlon, Inc.Inventor: Marvin E. Goldberg
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Patent number: 5063052Abstract: Cosmetic and dermatological application of polysiloxanes containing a diester functional group and compositions employed.The invention relates to the use in cosmetics and in dermatology of diorganopolysiloxanes containing a diester functional group carrying, per molecule, at least one unit of formula:ZR.sub.a SiO.sub.(3-a)/2where a is 0, 1 or 2, Z is a radical of formula: ##STR1## the symbols R', which are identical or different, denote a C.sub.1 -C.sub.12 monovalent saturated hydrocarbon, C.sub.2 -C.sub.12 alkoxyalkyl or C.sub.8 -C.sub.12 aryl, alkylaryl or aralkyl radical, X denotes H or CH.sub.3 ; W is a covalent bond or a C.sub.1 -C.sub.4 alkylene radical; and the symbols R, which are identical or different, denote C.sub.1 -C.sub.20 alkyl, vinyl, phenyl, 3,3,3-trifluoropropyl or hydroxyl, provided that only one radical R per silicon atom denotes hydroxyl.Type: GrantFiled: September 26, 1989Date of Patent: November 5, 1991Assignee: L'OrealInventors: Jean F. Grollier, Claude Dubief
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Patent number: 5061479Abstract: Use in cosmetics, as UV filters, of diorganopolysiloxanes containing a 3-benzylidenecamphor functional group of formula: ##STR1## R being C.sub.1 -C.sub.10 alkyl, phenyl or 3,3,3-trifluoropropyl, B denoting R or A, r=0-200, s=0-50, if s=0, at least one of the symbols B denotes A, or of formula: ##STR2## where u=1-20 and t=0-20,A and/or B denoting an optionally substituted alkylene or alkyleneoxy-3-benzylidenecamphor group.Type: GrantFiled: March 27, 1989Date of Patent: October 29, 1991Assignee: L'OrealInventors: Jean F. Grollier, Herve Richard, Serge Forestier, Gerard Lang
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Patent number: 5055456Abstract: This invention is concerned with a composition of matter and method of applying same for use as hair grooming aid or preferably, to treat androgenetic alopecia comprising (a) an effective amount of a polysaccharide or mixtures thereof, polysaccharide derivatives or mixtures thereof, or any combination of the foregoing; and (b) a minor amount of a fatty acid ester of sorbitol and its anhydrides, or mixture of said fatty acid esters; and (c) a minor amount of a lower alkyl ester of p-hydroxy benzoic acid or mixture of said esters; and (d) water sufficient to create a composition of 100% by volume.Type: GrantFiled: January 27, 1989Date of Patent: October 8, 1991Assignee: American Cyanamid Co.Inventors: Bruce J. Harris, James R. Lawter, Lawrence Ritter
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Patent number: 5053410Abstract: The invention relates to the combination of derivatives of pyrimidine and of nonsteroid antiinflammatory agents with a view to inducing and stimulating the growth of hair and reducing its loss.Type: GrantFiled: December 22, 1988Date of Patent: October 1, 1991Assignee: L'OrealInventors: Jean F. Grollier, Georges Rosenbaum
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Patent number: 5043162Abstract: Compositions containing mixtures of lower alkyl nicotinate and histamine hydrochloride, particularly useful in promoting hair growth and revitalizing the hair and scalp by topical application.Type: GrantFiled: September 5, 1990Date of Patent: August 27, 1991Inventor: Seymour F. Trager
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Patent number: 5041439Abstract: Topical pharmaceutical compositions containing a specific 6-amino-1,2-dihydro-1-hydroxy-2-iminopyrimidine component and a penetration-enhancing vehicle are disclosed. The vehicle comprises a binary combination of a C.sub.3 -C.sub.4 diol or C.sub.3 -C.sub.6 triol and isocetyl alcohol polar lipid compound. The vehicle provides marked transepidermal and percutaneous delivery of the iminopyrimidine compound. These compositions, when applied topically, act to stimulate the growth of mammalian hair on the body.Type: GrantFiled: November 20, 1990Date of Patent: August 20, 1991Assignee: The Procter & Gamble CompanyInventors: Gerald B. Kasting, Ellen R. Massaro, Ronald L. Smith, William E. Snyder
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Patent number: 5034221Abstract: A topical agent and method for the treatment and prevention of pseudofolliculitis barbae, commonly known as "razor bumps", is effected by the topical application to beard areas of the face of a combination of acetylsalicylic acid, corn starch, isopropyl alcohol, and aloe vera.Type: GrantFiled: June 22, 1989Date of Patent: July 23, 1991Inventors: Steven E. Rosen, Robert M. Thomas
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Patent number: 5034387Abstract: A compound having formula: ##STR1## is described, where R.sub.3 and R.sub.4 may be identical or different and represent a hydrogen atom, alkyl, alkenyl, cycloalkyl;or R.sub.3 and R.sub.4 represent aryl aralkyl;or R.sub.3 and R.sub.4 together with the nitrogen atom linked thereto form a heterocycle;R.sub.1 and/or R.sub.2, independent of each other, represent hydrogen or carbanoyl having formula: ##STR2## where R.sub.7 represents alkyl, alkenyl, cycloalkyl, aryl or aralkyl. The compounds of formula (I) can be used in cosmetic or pharmaceutical compositions for the cosmetic treatment of hair, the treatment of alopecia, and also for the treatment of desquamating dermatitis.Type: GrantFiled: February 21, 1990Date of Patent: July 23, 1991Assignee: L'OrealInventors: Jean Maignan, Serge Restle, Gerard Lang
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Patent number: 5030442Abstract: An aqueous, noncrystalline minoxidil composition for topical use which has significantly improved flux of the drug through human cadaver skin. The composition contains minoxidil complexed with an amphipathic compound, oleic acid and with pharmaceutically acceptable excipients. The composition may be formulated in an aqueous vehicle, or dispersed in fluorochlorocarbon solvent for spray delivery from a self- propelled spray device.Type: GrantFiled: April 4, 1989Date of Patent: July 9, 1991Assignee: Liposome Technology, Inc.Inventors: Paul S. Uster, Yolanda P. Quinn