Abstract: The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one glycerol fatty ester surfactant which is solid at a temperature of less than or equal to 45° C.; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion and methods for its use. Ideally, the emulsion is transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and, in the ophthalmological field, as an eye lotion for treating the eyes.

Abstract: An improved method of treating skin diseases comprises applying to the skin of a patient suffering such a skin disease an allantoin-containing composition in a therapeutically effective quantity. The allantoin-containing composition is a water-in-oil emulsion that includes allantoin and an emulsifier system that includes at least one emulsifier that is either an anionic emulsifier or a nonionic emulsifier. If the emulsifier is an anionic emulsifier, the emulsifier system can include beeswax. The nonionic emulsifiers used can include at least one nonionic emulsifier that is an ethoxylated ether or an ethoxylated ester whose carbon chain length ranges from 8 to 22 carbon atoms. Alternatively, the emulsifier system can include an acidic anionic polymer such as carboxypolymethylene and an anionic emulsifier. In another alternative, the emulsifier system can include the acidic anionic polymer and a nonionic emulsifier, or the acidic anionic polymer alone.

Abstract: W/O or O/W stable dispersions are formed by mixing an oily phase and an aqueous phase when the dispersion is stabilized with cubic gel particles formed by the combination of two amphiphilic compounds, one of the amphiphilic compounds being capable of forming a lamellar phase in the presence of water, and the other being capable of forming an inverse hexagonal phase in the presence of water.

Abstract: A stable medicated animal care formulation including, by weight; (a) 0.1-10% of an active agricultural ingredient, of an animal care and/or veterinary reagents, (b) 0.0002-40% of a microemulsion concentrate including: (i) 0-10% of a castor oil ethoxylate or tristyryl phenol ethoxylate, (ii) 0-1% of an ethoxylated phosphoric acid as pH buffer, (iii) 0.0002-4% of a N—C8-C18 alkyl pyrrolidone and (iv) 0-6% of a N—C1-C4 alkyl pyrrolidone, (c) a surfactant with shampoo properties, and (d) water, wherein (c)+(d) is 50-99.4%.

Abstract: Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability.

Abstract: A delayed release pharmaceutical dosage form for oral administration of a hydrophilic drug, e.g., a polysaccharide drug such as low molecular weight heparin, are provided. The dosage form comprises a composition of: (a) a therapeutically effective amount of low molecular weight heparin; (b) a bile salt or bile acid; (c) at least one surfactant selected from hydrophilic surfactants, lipophilic surfactants, and mixtures thereof; and a means for delaying release of the composition from the dosage form following oral administration. Osmotic drug delivery systems for oral administration of a hydrophilic drug are also provided, wherein an osmotically activated device houses the drug, a bile salt or bile acid, and at least one surfactant selected from the group consisting of hydrophilic surfactants, lipophilic surfactants, and mixtures thereof. Methods for administering hydrophilic drugs, particularly polysaccharide drugs such as low molecular weight heparin, are also provided.

Abstract: The present invention relates to triglyceride-free pharmaceutical compositions for delivery of hydrophobic therapeutic agents. Compositions of the present invention include a hydrophobic therapeutic agent and a carrier, where the carrier is formed from a combination of a hydrophilic surfactant and a hydrophobic surfactant. Upon dilution with an aqueous solvent, the composition forms a clear, aqueous dispersion of the surfactants containing the therapeutic agent. The invention also provides methods of treatment with hydrophobic therapeutic agents using these compositions.

Abstract: Pharmaceutical composition comprising micro particles having an average diameter ranging from 40 to 150 nm, consisting of one or more lipids, a drug and, optionally, a steric stabilizer, suitable to the transmucosal passage and to the overcoming of the blood-brain barrier and the blood-cerebrospinal fluid barrier, said micro particles being obtained dispersing in an aqueous medium cooled to 2-4° C. an oil/water or a water/oil/water micro emulsion comprising said constituents.

Abstract: Alkylmethylsiloxane-dimethylsiloxane polyalkylene oxide copolymers useful as surfactants for both oil-in-water emulsions and silicone-in-water emulsions are disclosed.

Abstract: The present application relates to novel oil-in-water emulsions comprising i) at least one specific 1,3,5-triazine derivative and ii) at least one polyalkyl-polyethersiloxane carrying polyoxyalkylene groups grafted onto the main silicone chain; with the proviso that the said emulsions do not comprise cetylstearyltrimethylammonium chloride. Another subject-matter of the present invention is the use of such emulsions in the manufacture of cosmetic or dermatological compositions intended for the photoprotection of the skin and/or hair and/or other keratinous substances against ultraviolet radiation, in particular solar radiation.

Abstract: The present invention relates to a nanoemulsion, the oil globules of which have an average size of less than 100 nm, comprising (1) a surfactant which is solid at a temperature of less than or equal to 45° C., which surfactant is chosen from sorbitan fatty esters and oxyethylenated sorbitan fatty esters, (2) at least one oil having a molecular weight of greater than 400 and (3) at least one ionic amphiphilic lipid chosen from the group formed by the alkaline salts of dicetyl and dimyristyl phosphate, the alkaline salts of cholesterol sulphate, the alkaline salts of cholesterol phosphate, lipoamino acids, the sodium salts of phosphatidic acid, cationic amphiphilic lipids and alkylsulfonic derivatives, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The surfactant used is, for example, chosen from sorbitan monostearate, sorbitan monopalmitate and sorbitan 20 EO tristearate. The emulsion obtained is transparent and stable on storage.

Abstract: An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 5.0 to about 6.5. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.

Abstract: Block copolymers containing a fluorinated hydrocarbon unit, a hydrocarbon unit, and a poly(oxyethylene) unit are useful in fluid formulations of pharmaceutical agents. A typical embodiment is: C11H23—CONHC2H4NHCO—C8F16—CONHC2H4NHCOO—(C2H4O)34—H.

Abstract: The present invention relates to a stabilized self-emulsifying system, comprising a therapeutically effective amount of o-(chloroacetylcarbamoyl)fumigillol, a pharmaceutically acceptable carrier and a stabilizing component, wherein the pharmaceutically acceptable carrier comprises an oily constituent and at least one surfactant. The stabilizing component comprises from about 1% to about 15% water relative to the weight of the self-emulsifying system, an acid, an adsorbent, or a complex-forming agent.

Abstract: The present invention relates to pharmaceutical compositions, pharmaceutical systems, and methods for enhanced absorption of hydrophilic therapeutic agents. Compositions and systems of the present invention include an absorption enhancing carrier, where the carrier is formed from a combination of at least two surfactants, at least one of which is hydrophilic. A hydrophilic therapeutic agent can be incorporated into the composition, or can be co-administered with the composition as part of a pharmaceutical system. The invention also provides methods of treatment with hydrophilic therapeutic agents using these compositions and systems.

Abstract: A skin cream composition containing allantoin and an emulsifier has improved stability coming from the adjustment of the pH to a range of 4.5 to 5.8. The lower pH preserves the stability of the allantoin and the functionality of the emulsifier system is maintained. The emulsifier system can be a nonionic emulsifier or an anionic emulsifier plus beeswax. The acid used to adjust the pH can be an organic acid or an inorganic acid. The composition can further comprise other ingredients such as herbal extracts, chelating agents, preservatives, emollients, solvents, and fragrance.

Abstract: Water-redispersible granules including at least one active material in the form of a hydrophobic liquid, at least one non-ionic surfactant selected from polyoxyalkylene derivatives, and at least one water-soluble compound selected from polyelectrolytes belonging to the weak polyacid family are disclosed. A method for prepang such granules by preparing an aqueous emulsion of at least one active material, at least one non-ionic surfactant and at least one water-soluble compound, and drying the resulting emulsion, is also disclosed.

Abstract: A clear, one-phase, efficacious aqueous microemulsion of an agriculturally active pyrethroid insecticide for delivery at a high loading of active is provided herein which is free of nonylphenol ethoxylate.

Abstract: A composition and method for the treatment of the conditions vulvar vestibulitis, interstitial cystitis, vulvar vaginitis or vaginitis dynea wherein a composition containing cromolyn sodium in effective amount is applied to the vaginal vestibule area, with the application repeated as necessary to effectively address the symptoms and conditions. Preferably, the cromolyn sodium is present in an amount of about 2 to 10 percent in a carrier ointment or cream, with the carrier composition preferably comprising a mixture of pluronic gel and lecithin organogel.

Abstract: The present invention relates to a leave-on antimicrobial composition comprising from about 0.001% to about 5% of an antimicrobial active; from about 0.5% to about 10% of an anionic surfactant; from about 0.1% to about 10% of a proton donating agent, wherein the proton donating agent is such that the composition is essentially free of C4-C20 alkyl fatty acid; and from about 0% to about 98.85% of water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0; wherein the leave-on antimicrobial composition has a One-wash Immediate Germ Reduction Index of greater than about 50%; and wherein the leave-on antimicrobial composition has a Mildness Index of greater than 0.3. The invention also encompasses methods for moisturizing skin, reducing germs on the skin, and providing residual effectiveness versus Gram positive bacteria using these products.

Abstract: In an apparatus for continuously manufacturing microspheres, a dispersed phase (O) is supplied to a chamber 27 for the dispersed phase inside of a bulkhead member 26 via a supply port 23. Thereafter, the dispersed phase enters into a gap 31 between a plate 22 via a supply port 29 in a base 25. The dispersed phase which enters into the gap 31 grows microspheres (particles) having a certain diameter while passing through a microchannel 33 by pressure applied by, for example, a pump, and is mixed with a continuous phase (W), so that microspheres are produced. The thus-produced microspheres float or are suspended in the continuous phase without needing any particular external force in response to their specific gravity, allowing the microspheres to be generated and withdrawn from a withdrawal port 32 at a significantly reduced pressure in comparison to conventional methods and apparatus.

Abstract: A stable monophasic liquid composition characterized by the ability to solubilize increased amounts of surfactant into the composition while retaining a monophasic state, the composition comprising: one or more surfactants selected from the group consisting of cationic surfactants, anionic surfactants, amphoteric surfactants, nonionic surfactants, and mixtures thereof; a hydrophobic material; and one or more coupling agents selected from the group consisting of straight, branched and cyclic alkanes containing 7 to 12 carbon atoms and substituted with two hydroxyl groups, and alkoxylates thereof containing up to 20 alkoxy units each of which is ethoxy, propoxy, or butoxy, and mixtures thereof, in an amount of the one or more coupling agents effective to increase the amount of the one or more surfactants that can be solubilized in the monophasic composition.

Abstract: An organic solvent-less O/W type emulsion having an excellent stability for storage and water-dilution is produced by a specific process in which (1) a mixture of (a) water with (b) an oily substance selected from oily effective materials and oily liquid materials, the oily substance and water being capable of forming an interface therebetween, (c) a high molecular weight surfactant and (d) a low molecular weight surfactant is stirred at a temperature of 40.degree. C. or less, to provide an O/W type emulsion; (2) the emulsion is heated to gel the emulsion; (3) the gel is heated to phase invert from O/W to W/O; (4) the W/O emulsion is cooled to a temperature below the gelling temperature; and (5) the resultant O/W emulsion is further stirred, and optionally in or after the cooling step (4), a particulate solid substance or an aqueous suspension thereof is mixed with the emulsion.

Abstract: An O/W/O type multiple emulsion in which an O/W type emulsion is dispersed in the outer phase oil wherein the O/W type emulsion in the inner phase contains water, an oil based ingredient, a surfactant and an amphiphilic substance chosen from those which can form a gel at ordinal temperature or higher in an amphiphilic substance-surfactant-oil-water system or N-long chain acyl acidic amino acid monosalt and an amphiphilic substance chosen from those which can form a gel at ordinal temperature or higher in an amphiphilic substance-N-long chain acyl acidic amino acid monosalt-oil-water system, said outer phase oil contains organophilic modified clay minerals and an emulsifying agent with a HLB of 7 or lower, and the weight ratio of the O/W type emulsion and the outer phase oil is 2:3-19:1. An O/W/O type multiple emulsion with superior stability over time and good usability.

Abstract: There is provided an emulsifier composition comprising (a) a blend consisting essentially of a polyoxyethylene (EO)/polyoxypropylene (PO) block copolymer which contains 10-40% EO, and where the molecular weight of the PO hydrophobe is about 500-6000; anionic surfactants; and a solvent; (b) a blend consisting essentially of a polyoxyethylene (EO)/polyoxypropylene (PO) block copolymer which contains 50-80% EO, and where the molecular weight of the PO hydrophobe is about 500-6000; anionic surfactants; and a solvent; and (c) a butyl ether of an EO/PO block copolymer.

Abstract: A method of lubrication of a mammalian joint or other physiological articulation which comprises administering a composition comprising one or more phospholipids in association with propylene glycol.

Abstract: A composition which is a silicone polyether containing arylalkyl groups, most preferably an arylalkyl group such as the 2-phenylpropyl group, i.e., --CH.sub.2 CH(C.sub.6 H.sub.5)CH.sub.3. The compositions demonstrate improvements in emulsification over silicone polyethers without such arylalkyl groups. The compositions have a formula generally corresponding toR.sub.3 SiO(R.sub.2 SiO).sub.x (RQSiO).sub.y (RQ'SiO).sub.z SiR.sub.3in which R is an alkyl group, Q is a polyoxyalkylene block, Q' is an arylalkyl radical, x is 0-500, y is 1-50, and z is 1-50. The compositions and emulsions containing the compositions have general utility, but are especially useful in the personal care arena.

Abstract: An oil-in-water emulsifier composition including between about 10 percent and about 70 percent by weight of a blend of mono- and diester phosphates of alkoxylated fatty alcohols containing between about 12 and 22 carbon atoms and alkoxylated with between about 1 and about 50 moles of an alkylene oxide selected from the group consisting of ethylene oxide, propylene oxide and mixtures thereof, wherein the mono- and diester ratio is between about 10:90 and about 90:10; and between about 90 percent and about 30 percent by weight of a blend of mono- and di-ester phosphates of fatty alcohols containing between 12 and 22 carbon atoms, wherein the mono- and diester ratio is between about 10:90 and about 90:10. Emulsifying waxes, oil-in-water emulsions and microemulsions, and topical compositions formulated therefrom are also disclosed.

Abstract: The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 6% to about 16%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 100:0 to about 1.5:1; from about 2% to about 4%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75, wherein the proton donating agent is such that the composition is essentially free of C.sub.4 -C.sub.20 alkyl fatty acid, and wherein from about 0.

Abstract: Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsifying agent, advantageously an anionic amphiphilic polymer, and (c) at least one biologically active agent, for example an active agent that modulates skin differentiation and/or proliferation and/or pigmentation, an anti-inflammatory, an antibacterial, an antifungal, etc.

Abstract: A heat and shelf-stable oil-in-water emulsion useful as a tissue or cell-selective delivery vehicle. Radioactive or stable, synthetic or semi-synthetic polyhalogenated triglycerides, such as 2-oleoylglycerol-1,3-bis[7-(3-amino-2,4,6-triiodophenyl)heptanoate] or 2-oleoylglycerol-1,3-bis[.omega.-(3,5-bis-trifluoromethyl)-heptanoate] or phenyl acetate, can be incorporated into the lipophilic core of a lipoprotein-like emulsion particle. The lipophilic core is surrounded by a phospholipid membrane comprising cholesterol and apolipoproteins. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm as measured by number weighting analysis with a narrow size distribution (<2% greater than 300 nm) and having a composition simulating naturally-occurring chylomicron remnants. Use of cholesterol in the emulsion formula facilitates association of apolipoproteins, especially Apo E which are recognized by liver cells and necessary for binding and uptake.

Abstract: A method is disclosed for controlling biofouling in an aqueous medium by treating the aqueous medium with an oil-in-water emulsion comprising an antimicrobial oil phase and at least one emulsifier. This method efficiently controls biofouling in the aqueous medium by specifically targeting the antimicrobial oil phase directly to biofilms, cell surfaces and cell aggregates in a concentrated form.

Abstract: The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily globule containing at least one lipophilic compound which is cosmetically or dermatologically active is individually coated with a monolamellar or oligolamellar layer obtained from at least one lipophilic surface-active agent, from at least one hydrophilic surface-active agent and from at least one ionic amphiphilic lipid imparting to the emulsion a pH ranging from 5.5 to 7.5, the coated oily globules having a mean diameter of less than 500 nanometers.

Abstract: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.

Abstract: Block copolymers containing a fluorinated hydrocarbon unit, a hydrocarbon unit, and a poly(oxyethylene) unit are useful in fluid formulations of pharmaceutical agents. A typical embodiment is:C.sub.11 H.sub.23 --CONHC.sub.2 H.sub.4 NHCO--C.sub.8 F.sub.16 --CONHC.sub.2 H.sub.4 NHCOO--(C.sub.2 H.sub.4 O).sub.34 --H.

Abstract: A clear, one-phase, efficacious aqueous microemulsion of an agriculturally active pyrethroid insecticide for delivery at a high loading of active is provided herein which is free of nonylphenol ethoxylate.

Abstract: Rinse-off, water-in-oil-in-water multiple emulsion compositions are disclosed. The multiple emulsion compositions comprise an external aqueous phase optionally incorporating an emulsifier and/or a second topically-active compound. The internal phase comprises a primary water-in-oil emulsion, wherein the primary emulsion comprises a first topically-active compound, a surfactant phase, an oil phase, and water.

Abstract: A water-in-volatile silicone emulsion gel having skin moisturizing qualities. The gel is formed by mixing an oil phase with a water phase. The oil phase contains a volatile silicone, a siloxane polyether, and an oil. The water phase contains water, a humectant, and an oxyethylene functional organosilane. Matching of the refractive index of the oil phase and the water phase results in the formation of a crystal clear gel having a viscosity in the range of 5,000 to 150,000 centistokes.

Abstract: Disclosed are compositions comprising paclitaxel; and a pharmaceutically-acceptable, water-miscible, non-aqueous solvent, together with kits comprising the composition and methods of using the composition.

Abstract: An oil-in-water emulsion useful as a delivery vehicle of hydrophobic ingredients such as pharmaceutical drugs and cosmetic active agent; wherein the emulsion particles have a net positive charge (i.e. a positive zeta potential).

Abstract: A sprayable or solid biodegradable wax carrier for insect pheromones and a method for constant release rate of the pheromone from the biodegradable wax. A composition comprising a pheromone and paraffin wax formulated as an aqueous emulsion or a solid suitable for application to a surface of a tree or crop for mating disruption of insect pests. Pheromone is released by diffusion or by partitioning from the biodegradable wax carrier or by pheromone exposure due to the biodegradable wax carrier degradation.

Abstract: Compositions for pain relieving non-steroidal anti-inflammatory drugs and/or medicaments such as ibuprofen, methotrexate, capsaicin, diphenhydramine, aspirin, methyl-nicotinate and other medicaments largely soluble in oil, alcohol, and/or water, are produced for transdermal delivery. The composition is manufactured by admixing an appropriate amount of oil surfactant with an appropriate amount of pharmaceutically approved co-solubilizer alcohol to establish a non aqueous phase. The oil surfactant may be a polyethoxylated oil such as castor oil. The co-solubilizer solubilizer may be isopropyl alcohol or virtually any other alcohols except for methanol. Thereafter, an appropriate amount of distilled water is slowly added to the homogeneous or non-aqueous phase to further reduce viscosity. The final admixture is a clear, oil-continuous solution having a viscosity no greater than 850 centistokes as measured by the VST Hoppler method at 25 degrees Celsius.

Abstract: An eye drop composition for alleviation of dry eye related symptoms in dry eye patients and contact lens wearers includes an emulsion of a higher fatty acid glyceride, polysorbate 80 and an emulsion stabilizing amount of Pemulen.RTM. in water suitable for topical application to ocular tissue.

Abstract: An anti-acne cosmetic composition in the form of a multiple phase water-in-oil emulsion and process for preparing thereof, wherein the composition comprises two or more aqueous phases and a coalescence inhibitor for preventing coalescence of the aqueous phases and wherein at least a first aqueous phase comprises the anti-acne active in the form of an aqueous/alcoholic solution. The composition exhibits moisturisation, anti-acne activityand skin anti-ageing benefits, together with product and colour stability.

Abstract: Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, 2-hydroxypropanoic acid, 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioicacid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone.

Abstract: Compositions suitable for cosmetic and/or dermatological use which contain a cosmetic and/or dermatological active agent, at least 20% of a fatty phase, a fatty acid ester of a C.sub.5 -C.sub.7 carbohydrate and polyol.

Abstract: A cosmetic composition consisting essentially of (i) a fatty phase, (ii) at least one fatty acid ester of a C.sub.5 -C.sub.7 carbohydrate, and (iii) at least one polyol.

Abstract: A stable oil-in-water emulsion suitable for parenteral administration, containing less than 10% by weight lecithin, consisting of an aqueous phase and of an oil phase which is very finely dispersed by means of a physiologically tolerated emulsifier and which contains at least one carotenoid and is based on a physiologically tolerated oil or fat and comprises as emulsifier polyoxyethylene/polyoxypropylene block polymers and/or lecithin, and wherein the carotenoid is present in the oil phase in a concentration above the saturation solubility of the carotenoid in the oil or fat at room temperature.

Abstract: The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily globule containing at least one lipophilic compound which is cosmetically or dermatologically active is individually coated with a monolamellar or aligolamellar layer obtained from at least one lipophilic surface-active agent, from at least one hydrophilic surface-active agent and from at least one ionic amphiphilic lipid imparting to the emulsion a pH ranging from 5.5 to 7.5, the coated oily globules having a mean diameter of less than 500 nanometers.

Abstract: A homogeneous, essentially nonaqueous adjuvant composition containing at least one spray oil selected from the group consisting of: (a) vegetable oils; (b) fatty acids and blends thereof; (c) esterified fatty acids or blends thereof; (d) saponified fatty acids or blends thereof; (e) N,N-dimethylamide of the formula RCON(CH3)2 (f) polybutenes of the following formula  a surfactant in an effective amount to emulsify said composition and a buffering agent in amount sufficient to reduce the pH to below about 7.