Polyoxyalkylated Compound Containing Patents (Class 514/941)
  • Patent number: 5925681
    Abstract: Concentrated aqueous liquid disinfectant compositions which exhibit a blooming effect when diluted in a larger volume of water are provided. The concentrate compositions include non-phenolic constituents to provide a disinfecting effect, and are non pine-oil containing. Working strength dilutions of the concentrated aqueous liquid disinfectant compositions are effective against gram positive type pathogenic bacteria such as Staphylococcus aureus, as well as gram negative type pathogenic bacteria such as Salmonella choleraesuis.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: July 20, 1999
    Assignee: Reckitt & Colman Inc.
    Inventors: Michael George Crisanti, Dennis Thomas Smialowicz
  • Patent number: 5922698
    Abstract: The invention relates to a pesticidal formulation having systemic activity and intended for application to a stem of a plant, which includes the compound methamidophos as an active ingredient, a suitable solvent for the active ingredient, and a colorant selected to impart an identifiable coloration to the formulation for a predetermined period of time related to the duration of the residual activity of the active ingredient. The solvent is preferably a non-volatile organic solvent selected for its low phytotoxicity and its low toxicity for humans, such as an aryl ethoxylate or a polyhydric alcohol. The colorant is preferably selected on the basis of its water solubility, having a limited solubility in water to be eluted gradually from the formulation over a period of time selected to coincide with the duration of the residual activity of the active ingredient. The formulation advantageously also includes an ingredient capable of screening ultra violet rays of the sun.
    Type: Grant
    Filed: July 12, 1994
    Date of Patent: July 13, 1999
    Assignee: Gouws & Scheepers (Proprietary) Limited
    Inventors: Martin David Bloomberg, Coenraad Jacobus Beukes Scholtz, Ian Francois Brink
  • Patent number: 5919830
    Abstract: A stable non-aqueous carrier for personal care compositions comprising:a) about 80-98% by weight of a liquid polyoxyalkylene glycol of MW=3000-100000;b) about 2-20% by weight of a non-ionic solid triblock EO/PO/EO copolymer of MW=8500-25,000.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: July 6, 1999
    Inventors: Sridhar Gopalkrishnan, Richard J. Holland, Kathleen M. Guiney
  • Patent number: 5916543
    Abstract: The invention encompasses oil-in-water type emulsion formulations having decreased skin rub-in times, comprising a nonaqueous phase, an aqueous phase and an oil-in-water emulsifier, which emulsion formulation also contains a water-in-oil emulsifier.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: June 29, 1999
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventor: Carl Kaplan
  • Patent number: 5912267
    Abstract: The subject of the invention is an aqueous suspension containing: 0.1-20% by mass beta-cypermethrin, 0-40% by mass other pesticide substance, 1-10% by mass surface active substances in total and within this, 1-5% by mass ethoxylated polyaryl-phenol-phosphate or sulfate, 0.1-25% by mass mineral and/or synthetic silicates, 0.1-1% by mass synthetic silicic acid and up to 100% by mass other auxiliary materials and water as dispersant.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: June 15, 1999
    Assignee: Chinoin Pharmaceutical & Chemical Works Co., Ltd.
    Inventors: Istvan Szekely, Sandor Botar, Bela Bertok, Janis Hajimichael, Jeno Kiraly, Janosne Hadobas, Laszlo Pap, B. Iidiko Menesine
  • Patent number: 5905072
    Abstract: Adjuvants for systemic fungicides in the form of a stable microemulsion comprise water, a mixture of methyl esters of fatty acids obtained by the transesterification of vegetable oils, an anionic surface-active agent, at least one non-ionic surface-active agent with an HLB of between 13-18 and a cloud point of >65.degree. and at least one non-ionic surface-active agent with an HLB of between 10 and 12. These adjuvants, which can additionally contain conventional components and/or formulation additives, improve the activity of systemic fungicides belonging to different chemical groups.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: May 18, 1999
    Assignee: Isagro S.p.A.
    Inventors: Luigi Capuzzi, Mario Ferri, Ernesto Signorini, Nicola Stramacchia, Claude Delestre, Luigi Mirenna
  • Patent number: 5886041
    Abstract: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: March 23, 1999
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5886042
    Abstract: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: March 23, 1999
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5883128
    Abstract: Preventive as wall as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: March 16, 1999
    Assignee: Tristrata Technology Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5869423
    Abstract: The present invention relates to oil-in-water emulsions containing 0.001 to 70% by weight of at least one active substance from the group consisting of phosphates, thiophosphates and/or carbamates, 0.001 to 30% by weight of one or more surfactant compounds from the group consisting of ethoxylated fatty amines or of phosphorylated fatty amine ethoxylates, and also, if desired, adjuvants and water to make up 100% by weight.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: February 9, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Frisch, Zoltan Damo
  • Patent number: 5863909
    Abstract: An adjuvant composition for agricultural chemicals comprising at least one sorbitan/fatty acid ester surfactant (A) and at least one surfactant (B) selected from the group consisting of resin acid surfactants and anionic oligomer or polymer type quaternary ammonium salt surfactants can be used for various crops in safety without causing injury thereof to the crops, and can enhance the efficacies of various agricultural chemicals.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: January 26, 1999
    Assignee: Kao Corporation
    Inventors: Kazuhiko Kurita, Keiko Hasebe, Katsuhiko Yamaguchi, Masaharu Hayashi, Yuichi Hioki
  • Patent number: 5858334
    Abstract: Stable and homogeneous, topically applicable cosmetic compositions well suited for artificially tanning human skin, comprise a storage-stable, ultrafine oil-in-water emulsion, devoid of lipid vesicles, containing an effective artificial tanning amount of dihydroxyacetone, and further wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically ranges from 100 nm to 1,000 nm.
    Type: Grant
    Filed: February 4, 1997
    Date of Patent: January 12, 1999
    Assignee: Societe L'Oreal S.A.
    Inventors: Jean-Marc Ascione, Delphine Allard, Isabelle Hansenne
  • Patent number: 5858398
    Abstract: A pharmaceutical composition comprises microparticles in micelle. The microparticles contain at least one pharmaceutically-active agent, at least one water soluble or miscible phospholipid, at least one lipid soluble or miscible phospholipid, at least one non-ionic surfactant having an HLB value of about 15 or greater, at least one non-ionic surfactant having an HLB value of about or less, and at least one water soluble or miscible sterol compound. The microparticles are suspended in at least one fatty acid having a chain length of C.sub.14 or less. The composition may optionally contain at least one fatty acid having a chain length of C.sub.16 or greater in a concentration of about 5 w/v % or less. The composition is prepared by admixing the pharmaceutically-active agent, phospholipids, surfactants, and sterol, micronizing the admixture to form microparticles, and suspending the microparticles in at least one fatty acid of chain length of C.sub.14 or less to form microparticles in micelle.
    Type: Grant
    Filed: May 2, 1996
    Date of Patent: January 12, 1999
    Assignee: Isomed Inc.
    Inventor: Young W. Cho
  • Patent number: 5851510
    Abstract: A heat and shelf-stable oil-in-water emulsion useful as a tissue or cell-selective delivery vehicle. Radioactive or stable, synthetic or semi-synthetic polyhalogenated triglycerides, such as 2-oleoylglycerol-1,3-bis?7-(3-amino-2,4,6-triiodophenyl)heptanoate! or 2-oleoylglycerol-1,3-bis?.omega.-(3,5-bis-trifluoromethyl)heptanoate! or phenyl acetate, can be incorporated into the lipophilic core of a lipoprotein-like emulsion particle. The lipophilic core is surrounded by a phospholipid membrane comprising cholesterol and apolipoproteins. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm as measured by number weighting analysis with a narrow size distribution (<2% greater than 300 nm) and having a composition simulating naturally-occurring chylomicron remnants. Use of cholesterol in the emulsion formula facilitates association of apolipoproteins, especially Apo E which are recognized by liver cells and necessary for binding and uptake.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: December 22, 1998
    Assignee: The Board of Regents of The University of Michigan
    Inventors: Raymond E. Counsell, Marc A. Longino, Jamey P. Weichert, Douglas A. Bakan
  • Patent number: 5846905
    Abstract: The present invention relates to oil-in-water emulsions containing 0.001-70% by weight of at least one active substance from the group consisting of phosphates, thiophosphates and/or carbamates, 0.001-30% by weight of one or more surfactant compounds from the group consisting of nonionic surfactant compounds or phosphorylated surfactant compounds or sulfated surfactant compounds or sulfonated surfactant compounds, and also, if desired, adjuvants, and, water to make up 100% by weight.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: December 8, 1998
    Assignee: Clariant GmbH
    Inventors: Gerhard Frisch, Zoltan Damo
  • Patent number: 5843334
    Abstract: There is provided a method of producing an emulsion by which an emulsion consisting of uniform and microfine globules can be easily obtained with a reduced energy input as compared with the conventional technology.This method of producing an emulsion comprises applying a back pressure equal to not less than 0.2% but less than 5% of the pressure acting on the point of high-pressure emulsifying action in a high-pressure emulsification zone in the course of production of an emulsion with a high-pressure emulsification equipment. The back pressure can be obtained typically by equipping an emulsification machine with a pipeline smaller in inside diameter than the discharge line of the machine.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: December 1, 1998
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Akira Saheki, Junzo Seki
  • Patent number: 5833973
    Abstract: A skin treatment composition is provided which includes a crosslinked non-emulsifying siloxane elastomer, a volatile siloxane and at least 50% by weight of water. Inclusion of the elastomer provides a unique liquid/powdery feel when rubbed into the skin.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: November 10, 1998
    Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.
    Inventors: Brian John Dobkowski, Alexander Paul Znaiden, Michael Charles Cheney, Walter Rose, Salvador Pliego
  • Patent number: 5834510
    Abstract: Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, 2-hydroxypropanoic acid, 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioic acid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 10, 1998
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5830483
    Abstract: An oil-in-water emulsion comprising(A) from about 50 to about 99% by weight of water;(B) from about 1 to about 30% by weight of an oil phase; and(C) an emulsifying effective quantity of an emulsifier system consisting essentially of(i) at least one nonionic emulsifier of formula (I):Z.sub.x R.sup.1 (R.sup.2 --CO).sub.y G.sub.z (I)in which Z is a sugar unit selected from the group consisting of pentoses and hexoses, x is a number of 1 to 5, R.sup.1 is a saturated alkyl radical containing 1 to 3 carbon atoms, R.sup.2 is a linear or branched alkyl radical or mono- or polyunsaturated alkenyl radical containing 8 to 22 carbon atoms, y is the number 1 or 2, G is a polyglycerol residue consisting of 2 to 10 glycerol units and z is the number 1 or 2, and(ii) at least one ionic emulsifier selected from the group consisting of cationic and anionic emulsifiers.
    Type: Grant
    Filed: September 12, 1996
    Date of Patent: November 3, 1998
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Kurt Seidel, Christian Priebe, Detlef Hollenberg
  • Patent number: 5817254
    Abstract: An aqueous emulsion concentrate comprising:A) a water-insoluble oil component;B) at least one hydrophilic nonionic emulsifier;C) at least one lipophilic co-emulsifier; andD) from about 50 to about 70% by weight of water, based on the weight of the concentrate;wherein components A), B) and C) are present in a ratio by weight of A:B:C of 1:(0.31-1.5):(0.31-1.5); and wherein the emulsion concentrate is flowable and pumpable at 20.degree. C.
    Type: Grant
    Filed: May 14, 1996
    Date of Patent: October 6, 1998
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Armin Wadle, Achim Ansmann, Guido Baumoeller, Holger Tesmann
  • Patent number: 5804216
    Abstract: A composition containing a dispersion of lipid vesicles with an aqueous core and/or of lipid vesicles with an oily core. At least one acidic compound is present in the dispersion in an amount which is sufficient to impart a pH of less than 5 to the composition. The lipid membrane of the vesicles with an aqueous core does not contain:(a) acidic amphiphilic lipids(b) or non-hydrogenated soya lecithin in the presence of glycerol in the dispersion.The composition is stable and may be stored for several months.
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: September 8, 1998
    Assignee: L'Oreal
    Inventors: Nadia Terren, Jacques Michelet, Martine Perrin
  • Patent number: 5798346
    Abstract: The invention relates to a pesticidal formulation having systemic activity and intended for application to a stem of a plant, which includes the compound methamidophos as an active ingredient, a suitable solvent for the active ingredient, and a colorant selected to impart an identifiable coloration to the formulation for a predeterminable period of time related to the duration of the residual activity of the active ingredient. The solvent is preferably a non-volatile organic solvent selected for its low phytotoxicity and its low toxicity for humans, such as an aryl ethoxylate or a polyhydric alcohol. The colorant is preferably selected on the basis of its water solubility, having a limited solubility in water to be eluted gradually from the formulation over a period of time selected to coincide with the duration of the residual activity of the active ingredient. The formulation advantageously also includes an ingredient capable of screening ultra violet rays of the sun.
    Type: Grant
    Filed: July 12, 1994
    Date of Patent: August 25, 1998
    Assignee: Gouws & Scheepers (Proprietary) Limited
    Inventors: Martin David Bloomberg, Coenraad Jacobus Beukes Scholtz, Ian Francois Brink
  • Patent number: 5750122
    Abstract: The present invention relates to compositions useful for treating hair or skin. These compositions comprise a topical vehicle containing panthenol and a polyalkyleneglycol having from 3 to about 12 repeating ethyleneglycol or propyleneglycol units.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: May 12, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Joel Franklin Evans, Bruce Russell Cox, Michael Thomas Dodd, Jeffrey Jon Hopkins
  • Patent number: 5750124
    Abstract: Multiple emulsions of the W/O/W type having a continuous external aqueous phase, an oily phase dispersed therein and a second (internal) aqueous phase dispersed in this oily phase, comprising(a) at least one emulsifier whose lipophilicity increases with increasing temperature and the hydrophilicity of which increases with decreasing temperature, the emulsifier or emulsifiers changing from an HLB value <10 to an HLB value >10 in the temperature range of 40.degree.-90.degree. C.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: May 12, 1998
    Assignee: Beiersdorf Ag
    Inventors: Sven Gohla, Anja Muller, Jens Nielsen
  • Patent number: 5741502
    Abstract: A homogeneous, essentially nonaqueous adjuvant composition containing at least one spray oil selected from the group consisting of:(a) vegetable oils;(b) fatty acids and blends thereof;(c) esterified fatty acids or blends thereof;(d) saponified fatty acids or blends thereof;(e) N,N-dimethylamide of the formulaRCON(CH.sub.3).sub.2wherein R is an alkyl chain derived from fatty acids having about 6 to about 18 carbon atoms;(f) polybutenes(g) alpha or beta pinene,(h) thymol,(i) d-limonene and(j) jojoba bean oil,(2) a surfactant in an effective amount to provide emulsification of said composition and(3) a buffering agent wherein said buffering agent can also be the same ingredient as said oil or said surfactant and said buffering agent reduces the pH of said composition to about 7 or below.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: April 21, 1998
    Assignee: Helena Chemical Co.
    Inventor: Johnnie R. Roberts
  • Patent number: 5738839
    Abstract: The present invention relates to gelled emulsion particles obtained when predetermined volumes, especially drops, of an emulsion with an aqueous external phase, containing an appropriate reagent in solution in the said aqueous phase, are added to a gelling solution and left therein for a period of time which depends on the degree of gelling desired for the said particles.It further relates to compositions--especially solutions, gels or emulsions with an aqueous external phase--in which the said particles are present.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 14, 1998
    Assignee: Helene Rubenstein, Inc.
    Inventors: Anne Clement, Pierre Fodor, Gerard Guth, Nathalie Thiollet
  • Patent number: 5723137
    Abstract: A process for producing a storage-stable, fine-particle wax dispersion by heating a mixture containing(A) 10% to 80% by weight of a wax,(B) 0.5% to 30% by weight of a hydrophilic nonionic dispersant having an HLB value of 8 to 18, and(C) 1% to 30% by weight of a hydrophobic co-dispersant selected from the group consisting of fatty alcohols containing 12 to 22 carbon atoms and partial esters of polyols containing 3 to 6 carbon atoms with fatty acids containing 12 to 22 carbon atoms,with the proviso that the weight ratio of component (B) to component (C) is in the range from 0.5:1 to 20:1, in the presence of 15% to 85% by weight of water to a temperature above the melting point of the mixture of components (A) to (C) to form a dispersion, heating the dispersion to its phase inversion temperature, and then cooling the dispersion to a temperature below its phase inversion temperature.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: March 3, 1998
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Bernd Wahle, Peter Waltenberger, Claudia Klink, Thomas Foerster, Thomas Engels
  • Patent number: 5716992
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin mucic acid or mucolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 10, 1998
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5702688
    Abstract: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, ache, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
    Type: Grant
    Filed: October 7, 1993
    Date of Patent: December 30, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5700472
    Abstract: The present invention relates to oil-in-water emulsions comprising 0.001-70% by weight, preferably from 0.5 to 45% by weight, of at least one active substance from the class of the phosphates and/or carbamates, from 0.001-20% by weight, preferably from 0.1-10% by weight, of at least one salt of an aryl polyglycol ether phosphate of the formula I ##STR1## in which each R.sup.1, independently of the others, is hydrogen, C.sub.1 -C.sub.24 -alkyl, C.sub.5 -C.sub.15 -cycloalkyl, C.sub.8 -C.sub.24 -aryl or C.sub.6 -C.sub.24 -alkaryl,R.sup.2 is hydrogen, --O--C.sub.1 -C.sub.24 -alkyl, --O--C.sub.5 --C.sub.15 -cycloalkyl, --O--C.sub.6 -C.sub.18 -aryl or A,M is an alkali metal ion, alkaline earth metal ion or ammonium ion of the formula HN(R.sup.3).sub.3, where each R.sup.3, independently of the others, is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.5 -C.sub.15 -cycloalkyl, C.sub.6 -C.sub.18 -aryl or a group of the formula --(CH.sub.2).sub.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: December 23, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Frisch, Zoltan Damo
  • Patent number: 5690967
    Abstract: Compositions for improved topical delivery of lactic acid comprising lactic acid and an amphoteric or pseudoamphoteric agent.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 25, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5679351
    Abstract: A clove oil formulation which inhibits soil-borne fungal diseases is disclosed. The formulation includes about 70-90% by weight rectified clove oil, and about 2-30% by weight surfactant. The surfactant includes about 15-95% by weight nonionic compounds such as ethoxylated monoglycerides, ethoxylated diglycerides, ethoxylated alcohols, silicone glycol copolymers, sorbitan fatty acid esters, ethoxylated alkyl phenols, ethylene oxide block copolymers, and propylene oxide block copolymers. The surfactant further includes about 5-85% by weight anionic compounds such as amine alkylaryl sulfonate, calcium alkylaryl sulfonate and phosphate esters. The formulation may also include up to about 30% by weight of a solvent such as alcohol, esters, glycol ethers, mineral oil, methyl esters and hydrocarbon solvents.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 21, 1997
    Assignee: Thermo Trilogy Corporation
    Inventors: James Frederic Walter, James Charles Locke, Michele Carter Normoyle
  • Patent number: 5672564
    Abstract: An aqueous, multiphase, stable finished formulation for crop protection active compounds is described, containing in addition to watera) 10 to 700 g/l of one or more crop protection active compounds,b) 5 to 150 g/l of one or more dispersants,c) 50 to 500 g/l of one or more wetting agents,d) 0.5 to 5 g/l of one or more thickeners ande) if appropriate an organic solventand processes for preparation thereof are described.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: September 30, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: August Wigger, Hans-Michael Fricke, Uwe Kardorff, Adolf Parg, Reiner Kober
  • Patent number: 5670139
    Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion resistant to phase separation/settling, of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, as well as a stabilizing amount of at least one mixed silicate which comprises alkali and/or alkaline earth metals, and further wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically ranges from 100 nm to 1,000 nm.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: September 23, 1997
    Assignee: L'Oreal
    Inventors: Delphine Allard, Jean-Marc Ascione
  • Patent number: 5656665
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin quinic acid or quinolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 12, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5656666
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin ribonic acid or ribonolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 12, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5656616
    Abstract: An insecticidal composition comprising an effective amount of a biocide and an effective amount of a insecticide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a hydroxyalkyl phosphate, a polyoxyalkylene alkyl ether phosphate, a salt thereof, a polyoxyalkylene alkenyl ether phosphate, a salt thereof, a polyoxyalkylene hydroxyalkyl ether phosphate and a salt thereof.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 12, 1997
    Assignee: KAO Corporation
    Inventor: Tetsuji Iwasaki
  • Patent number: 5656289
    Abstract: Orally or rectally administrable formulations of biologically active material comprise a water-in-oil microemulsion, wherein the hydrophilic phase of the microemulsion comprises the biologically active material and the hydrophobic phase comprises chylomicra or material capable of forming chylomicra in the intestinal mucosa after administration. The biologically active material may be any of a wide range of substances including insulin, calcitonin and somatotrophin or growth hormone. Formulations of the invention are particularly suitable for the oral administration of insulin in the treatment of diabetes.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: August 12, 1997
    Assignee: Patralan Limited
    Inventors: Young W. Cho, Michael John Flynn
  • Patent number: 5654340
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin gulonic acid or gulonolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 5, 1997
    Assignee: Tristrata Technology
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5654291
    Abstract: A biocide composition comprises an effective amount of a biocide and an effective amount of a biocide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a hydroxyalkyl phosphate, a polyoxyalkylene alkyl ether phosphate, a salt thereof, a polyoxyalkylene alkenyl ether phosphate, a salt thereof, a polyoxyalkylene hydroxyalkyl ether phosphate and a salt thereof.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: August 5, 1997
    Assignee: Kao Corporation
    Inventor: Tetsuji Iwasaki
  • Patent number: 5653989
    Abstract: The application is directed to a water-in-oil lotion containing hydrocotisone-21-acetate-17-propionate and one of four compositions containing a water-in-oil emulsion. The lotion is suitable for use on dry skin, it has good spreadability on large surface areas and it is dermatologically acceptable.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: August 5, 1997
    Assignee: Galderma S.A.
    Inventor: Henning Sattler
  • Patent number: 5652267
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin saccharic acid or saccharolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 29, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5650436
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin galactonic acid or galactonolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 22, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5650440
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin citramalic acid.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 22, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5650437
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin benzilic acid.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 22, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5648389
    Abstract: The present invention provides compositions and methods for alleviation of both visible and non-visible, or pre-emergent, dermatological lesions associated with changes in normal keratinization, cutaneous infection, epidermal formation or pilosebaceous function, such as acne, psoriasis, seborrhea, ingrown hairs and pseudofolliculitis barbae, and hyperpigmented skin. The inventive compositions comprise a dermatologically absorbable topical antimicrobial, antibiotic, antibacterial or antifungal agent; a dermatologically absorbable alpha or beta hydroxy acid; and a dermatologically absorbable zinc compound in a suitable carrier.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: July 15, 1997
    Assignee: Medicis Pharmaceutical, Inc.
    Inventors: Eugene H. Gans, Jonah Shacknai
  • Patent number: 5648388
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin methyllactic acid.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 15, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5648391
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin galacturonic acid or galacturonolactone.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 15, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5643963
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin isocitric acid.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 1997
    Assignee: Tristrata Technology, Inc.
    Inventors: Ruey J. Yu, Eugene J. Van Scott
  • Patent number: 5643953
    Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin 3-phenyllactic acid.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 1997
    Assignee: Tristrata Technology
    Inventors: Ruey J. Yu, Eugene J. Van Scott