Abstract: Plastics materials may be plasticized using lipids as the sole plasticizer or in combination with conventional plasticizers. When appropriate lipids are used thermosetting plastics and elastomers may be rendered biocompatible or therapeutic articles and substained release medicaments may be formed.

Abstract: Hydrocolloid adhesive compositions for use as wound dressings or ostomy/prosthesis adhesives are disclosed. These adhesive compositions are made of a mixture of a hydrophobic, unsaturated, elastomeric homopolymer, a polyisobutylene tackifier and a hydrocolloid absorbent which is cross-linked by 5-200 kGy gamma radiation to provide a cross-linked matrix having a wet integrity value of at least about eighty percent, a shear hold value of at least about 500 min/500 g and a dry cohesive strength which prevents adhesive composition breakage or delamination. Methods of using such wound dressings or ostomy/prosthesis adhesives and methods of making the hydrocolloid adhesive compositions are also disclosed.

Abstract: A new conservative method of conditioning enamel, dentin and other similar substrates, for obtaining strong and durable adhesive bonding of polymeric materials is disclosed. The method of conditioning addresses both the inorganic and organic phases of the tooth and is based on the concept of formation of a unitary polymeric network comprising the tooth structure and the restorative material, including an intermediary smear layer chemically modified and transformed into a stable, uniform and porous layer by rubbing the tooth surface with an aqueous solution of mild polyfunctional organic acids (pH=1.2-3.5).

Abstract: A pressure sensitive hot melt adhesive comprising a block copolymer and 60 to 95 parts of a liquid diluent, the adhesive being characterized by a midblock Tg less than -10.degree. C., a G' less than 15.times.10.sup.4 dynes/cm.sup.2 at 10 rad/s, 25.degree. C., a G" of 1 to 6.times.10.sup.4 dynes/cm.sup.2 and a tensile strength greater than 10 psi exhibit superior properties, without the need for any curing operation after cooling.

Abstract: The present invention relates generally to the field of biological and medical adhesives and encompasses more specifically the closing of microsurgical wounds and other tissue wounds and defects due to surgical procedures or other causes. A medical adhesive comprising a photosensitizing species and an protein or peptide containing moiety are disclosed which may be applied to various tissues, an adhesive bond being formed by exposure of the adhesive to photoactivating radiation.

Abstract: A hydrophilic, pressure sensitive adhesive of a poly(ethylene oxide) derived network plasticized with an essentially non-volatile, polar plasticizer present in an amount sufficient to form a cohesive, pressure sensitive adhesive. The polymeric network is prepared from an oligomeric precursor comprising difunctional poly(ethylene glycol) moieties which have been end-capped with ethylenically unsaturation. The adhesive is useful as a biomedical adhesive for transmitting or receiving electrical signals as a component of a biomedical electrode. The adhesive is also useful as a drug delivery device to deliver pharmaceuticals or other active ingredients to or through mammalian skin. The adhesive is also useful as a component in a skin covering for protecting mammalian skin or mammalian skin openings with antimicrobial agents. A method of preparation of the adhesive is also disclosed.

Abstract: Ad adhesive composition suitable for wound dressing and other medical applications comprising a mixture of polyisobutylene and a rubber polymer selected from the group consisting of random styrene butadiene copolymer (SBR) and halobutyl rubber so as to form a rubbery elastomer base matrix, and at least one hydrocolloid. The addition of the SBR or halobutyl rubber to the elastomer base offsets the possible degradation of the polyisobutylene upon sterilization, and therefore, helps to maintain the integrity of the composition. Water soluble hydrocolloid gums and water swellable cohesive strengthening agents are dispersed within the base matrix and may carry a pharmaceutical agent to be dispensed directly to a wound site.

Abstract: A curable cyanoacrylate adhesive composition intended for medical and/or veterinary uses is sterilized in liquid form by gamma irradiation. The composition comprisesa) a cyanoacrylate monomerb) a combination of an anionic stabilizer and a free-radical stabilizer in amounts effective to stabilize the composition during irradiation and to stabilize the sterilized composition during storage prior to cure, wherein the free radical stabilizer is a selected phenolic antioxidant (but not including hydroquinone).The preferred free radical stabilizer is butylated hydroxyanisole. After irradiation the cyanoacrylate monomer is substantially ungelled.

Abstract: There is provided a highly biodegradable resin composition comprising a hydroxyalkanoate polymer and a crystallization nucleating agent. The resin composition may typically comprise a hydroxybutyrate homopolymer or a hydroxybutyrate-hydroxyvalerate copolymer and an aromatic amino acid. There is also provided a device prepared by using such a resin composition. The resin composition of the invention is capable of undergoing a crystallization at a high speed to provide the article molded therefrom with improved properties. The resin composition is also highly degradable in an animal body or in the environment.

Abstract: Polymers containing a plurality of free hydroxy groups, such as cellulose, agarose or polyvinyl alcohol, are contacted in absence of reactants for hydroxy groups, with at least one N-heterocyclic compound, e.g. pyridine, pyrrole, pyridazine, their partially or fully hydrogenated analogs and any of these which may be substituted, in a pre-activation step prior to reaction with reactant for free hydroxy groups in the polymer, the polymer-bound residue of which reactant may be thereafter reacted in turn with amino compounds containing at least one unsubstituted N-attached hydrogen atom, e.g. proteins, thereby to form amine-polymer conjugates. The invention further relates to a powder, bandage, patch or like cover for application to wounds which has been manufactured from polymer containing a plurality of hydroxy groups by a process which includes the step of providing an amine conjugated to the polymer; the amine may be, e.g., trypsin, chymotrypsin, lysozyme, collagenase, albumin and hyaluronidase.

Abstract: The present invention provides a radiation curable vinyl-silicone pressure-sensitive adhesive composition which combines the advantages of silicone and acrylate pressure-sensitive adhesives and which does not experience gross phase separation problems. The composition comprises at least about 20 weight percent of a certain telechelic silicone polymer, about 0.5 to about 80 weight percent of monofunctional free-radically polymerizable vinyl monomer copolymerizable with the silicone polymer, and a sufficient amount of a silicate MQ tackifying resin to impart a degree of adhesive tack to the cured composition at the use temperature, wherein the weight percentages of the silicone polymer and the monomer are based upon the total weight of the silicone polymer and monomer.

Abstract: The invention relates to an adhesive, biocompatible, biodegradable and non-toxic composition for surgical use, in particular for binding tissues, which composition is of the following general formula: ##STR1## in which: R is a hydrocarbon chain containing from 1 to 50 carbon atoms,R.sub.1 and R.sub.2 are identical or different and are chosen from the following groups: ##STR2## R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.

Abstract: A pressure sensitive adhesive composition particularly suitable for use as a protective skin barrier material for sealing the faceplate of an ostomy appliance, such as the faceplate of a one-piece or two-piece urostomy or an ileostomy appliance, to skin surfaces surrounding a patient's stoma. The composition includes a blend of two viscoelastic adhesive elastomers, specifically, high molecular weight polyisobutylene and a styrene block copolymer, which, along with a plasticizer (preferably petrolatum) and a suitable tackifier and antioxidant, form a continuous phase in which hydrocolloids such as sodium carboxymethylcellulose and pectin are dispersed. The composition is exceptional for its durability, flexibility and strength, even when saturated, and for its controlled swelling upon hydration.

Abstract: An adhesive hydrogel product includes a mixture comprising water, and a thermoplastic, water-soluble polymer extruded in a dry state. The thermoplastic, water-soluble polymer constitutes the principal water-soluble polymer of the mixture and is present in the mixture in a concentration, by weight, of at least 15 percent. The mixture having been exposed to a dose of radiant energy effective to provide an adhesive hydrophilic gel having a gel breaking strength of at least 10 p.s.i., and an absorption capacity per mil of thickness of the gel in excess of 10% by weight, and more preferably in excess of 30% by weight.

Abstract: A sheet material, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer, is used for bonding of tissues, with improved handleability.Surgical instruments, comprising a non-adherent material towards an NCO-terminated urethane prepolymer, are used for application of surgical adhesive. Such instruments, comprising a rod tapered so that the tip can be partly inserted into blood vessel, are suitable for anastomosis of blood vessel.

Abstract: An adhesive composition suitable for wound dressing and other medical applications comprising a mixture of polyisobutylene and a rubber polymer selected from the group consisting of random styrene butadiene rubber (SBR) and halobutyl rubber so as to form a rubbery elastomer base matrix, and at least one hydrocolloid. The addition of the SBR or halobutyl rubber to the elastomer base offsets the possible degradation of the polyisobutylene upon sterilization, and therefore, helps to maintain the integrity of the composition. Water soluble hydrocolloid gums and water swellable cohesive strengthening agents are dispersed within the base matrix and may carry a pharmaceutical agent to be dispensed directly to a wound site.

Abstract: Photocurable glycosaminoglycan (GAG) derivatives and crosslinked glycosaminoglycans, which are highly safe and biocompatible, a method of preparing such photocurable GAG derivatives readily moldable by casting using a solvent when desired, by which method unreacted substances causative of adverse effects can be readily eliminated, and a method of producing the crosslinked GAGs and medical materials based on the photocurable GAG derivatives or crosslinked GAGs are provided. The photocurable GAG derivatives comprise a glycosaminoglycan and a photoreactive compound bound thereto and can be produced, for example, by subjecting hydroxyl or carboxyl groups of the glycosaminoglycan to esterification reaction or amidation reaction, respectively, with the photoreactive compound. The crosslinked GAGs are derived from the photocurable GAG derivatives by intermolecular crosslinking of the photoreactive compound bound thereto.

Abstract: Described is the use of physiologically compatible tocopherols and especially of vitamin E as an inhibitor against premature polymerization initiation in reactive systems capable of undergoing a free radical-initiated polymerization, which systems before and/or after the polymerization thereof are placed in tissue contact with the living human or animal body and, more specifically, are implanted into the living organism thereby. The reactive systems and the polymers formed therefrom may be degradation resistant. However, a special embodiment relates to compositions or molded bodies which are decomposed by the living organism, and especially so under time-controlled conditions.

Abstract: An adhesive for soft tissue comprising at least one member selected from (meth)acrylic esters each containing an acid anhydride group represented by the specific formula (I) and derivatives of the (meth)acrylic esters represented by the specific formula (Ia), a (meth)acylate, a poly(meth)acrylate derived from a (meth)acrylate and a polymerization initiator; and a kit of an adhesive for soft tissue, comprising containers and, placed therein, the above ingredients.

Abstract: A sheet material, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer, is used for bonding of tissues, with improved handleability.Surgical instruments, comprising a non-adherent material towards an NCO-terminated urethane prepolymer, are used for application of surgical adhesive. Such instruments, comprising a rod tapered so that the tip can be partly inserted into blood vessel, are suitable for anastomosis of blood vessel.

Abstract: The invention concerns an electrically conductive, transparent, pressure-sensitive adhesive film with an electric conductivity above 10.sup.-5 S, for the production of biomedical electrodes, consisting of100 parts by weight of a carboxyl group-containing copolymer on an acrylate basis;50 to 150 parts by weight of a water-soluble amine;50 to 250 parts by weight of a polyoxyalkylene with a molecular mass of below 1000 and/or a polyalcohol and/or its derivatives;50 to 200 parts by weight of a solution of electrolytes and0.1 to 6 parts by weight of a cross-linking agent.

Abstract: The present invention provides a wound dressing in the form of a gauze or similar absorbent material having dehydrated hydrogel material impregnated therein for absorbing wound exudate. The dehydrated hydrogel material is formed from an aqueous mixture comprising: (a) from about 0% to about 90% by weight polyhydric alcohol; (b) from about 6% to about 60% by weight aliphatic diisocyanate terminated prepolymer; (c) from about 4% to about 40% by weight polyethylene oxide based polyamine; (d) 0% to about 2% by weight sodium chloride; and (e) the balance water. The present wound dressing is capable of absorbing large amounts of wound exudate without inhibiting the healing of the wound to which it is contacted since it does not adhere to such a wound.

Abstract: A dressing comprising a backing and an adhesive layer, wherein the backing is moisture-permeable and the adhesive layer comprises an adhesive composition comprising a rubber-based adhesive, a polymer having a water-absorbing property and/or a water-swelling property, and a metal oxide and/or a metal salt, the polymer having the water-absorbing property and/or the water-swelling property being a polymer containing a functional group having an ability to form a salt and/or coordination compound.

Abstract: A hydrophilic, pressure-sensitive adhesive composition prepared by irradiating solid poly(N-vinyl lactam) with ionizing radiation to crosslink the poly(N-vinyl lactam) and thereafter mixing the radiation-crosslinked poly(N-vinyl lactam) with essentially unirradiated plasticizer in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition. The composition is useful as a biomedical adhesive for transmitting or receiving electrical signals as a component of a biomedical electrode. The composition is also useful as a drug delivery device to deliver pharmaceuticals or other active ingredients to or through mammalian skin. The composition is also useful as a component in a skin covering for protecting mammalian skin Or mammalian skin openings with antimicrobial agents. A method of preparation of the composition is also disclosed.

Abstract: Materials based on gypsum and organic additives are improved if they contain polyethers and, if desired, polymers. They can be used in a wide range of areas, for example as slabs in the building sector and for improving plasters, mortars, insulating materials and other construction compositions, casts and/or moulds.

Abstract: A composite of a gel of swollen hydrocolloid dispersed in a pressure sensitive adhesive matrix is provided. The gel has a natural or synthetically derived hydrocolloid swollen with a non-volatile swelling agent, such that the gel may have a shear modulus of less than 6.2.times.10.sub.6 dynes/cm.sup.2 The gel-adhesive composite has continued skin adhesion whether applied to or existing in dry or moist skin conditions. The gel contributes a high moisture vapor transmission rate to attempt to maintain dry skin conditions while the adhesive maintains skin adhesion. The gel-adhesive composite may be used in a variety of tape, dressing, bandage, drape, or other skin contacting usage and may optionally include antimicrobial agents to treat the skin while adhesion continues.

Abstract: A method is disclosed for the preparation of non-stringy hydrogels that are comprised of a homogeneous uniform mixture of water and at least one water-soluble high molecular weight polymer. Suitable mixtures may be derived from poly(ethylene oxide) and water or poly(vinyl pyrrolidone), a viscosity enhancing hydrophilic polymer and water, and further, may optionally contain an effective amount of a water-soluble electrolyte to provide conductive non-stringy materials. These polymeric mixtures are crosslinked by exposure to radiant energy to provide gel-like solids which are sufficiently tacky and adhesive to adhere to the subjects' skin and yet are substantially non-stringy and non-aggressive such that contact with such hydrogels imparts less discomfort to the user. In addition, the consumer utilizing the products of this invention would not experience the objectionable sticky, stringy sensation associated with existing adhesive gels.

Abstract: A wetness indicating hot melt adhesive composition comprising:a) a graft copolymer ofi. about 40-80% by weight of vinyl monomer; andii. about 20-60% by weight of water-soluble polyalkylene oxide polymer having a molecular weight of about 3,000-20,000 and a polymerized ethylene oxide content of at least 50% by weight; andb) an effective amount of a wetness indicating agent.

Abstract: A cyanoacrylate adhesive is applied to the skin areas prone to blistering prior to blister formation.

Abstract: Acrylic pressure sensitive adhesives which exhibit hydrophilicity and moisture permeability can be made by curing or crosslinking low molecular weight acrylic oligomers modified with substantial quantities of a hydroxyl containing monomer. The resultant modified pressure sensitive adhesive acrylic copolymers, upon crosslinking, will then have a hydrophilic hydroxy component incorporated into the copolymer backbone. Such adhesives are particularly useful in skin contact applications, such as the adhesives used on bandages or the adhesives used in transdermal drug delivery systems.

Abstract: A salt of an uncrosslinked copolymer of a monoethylenically unsaturated mono- or dicarboxylic acid and an alkyl ester of acrylic or methacrylic acid is suitable as a pressure-sensitive skin adhesive for plasters, for transdermal pharmaceutical forms, or for fastening bandages, which is permanently flexible and can be washed off with water, for which the proportion of carboxylic acid has to be sufficient to make the copolymer water-soluble in the salt form.

Abstract: Therapeutic gels are provided which promote the healing of wounds and which have a minimum yield point of about 800 poise and a maximum apparent viscosity of about 100,000 cps, which gels comprise water, sodium chloride, and a gelling agent.

Abstract: A method of using a pressure sensitive adhesive to form a moisture resistant, water-dispersible tape is provided. The adhesive and tape are resistant to autoclavation conditions and/or moisture and body fluids during usage, and are water-dispersible when immersed in aqueous solutions. The tape may be used with cloth body coverings, such as garments such as hospital gowns, drapes, dressings, diapers and other body coverings which require cloth to cloth or cloth to skin adhesion in the presence of moisture and bodily fluids yet be dispersible from such body coverings during laundering or other aqueous alkali immersion.

Abstract: Novel non-elastomeric biomedical adhesive compositions for calcified tissues, are described. The compositions are characterized by a network structure which is obtained by the reaction of a polyisocyanate having at least two isocyanate groups with at least one polyol which possesses surface wetting properties with the participation of compounds selected from calcium and phosphorus, optional in the presence of a catalyst. The polyisocyanate is selected from aliphatic, alicyclic and aromatic compounds and preferred amounts are in the range of 20% to 80% by weight of the total amount of reactants. The polyol is selected from polyalkylene ether glycols and polyester glycols containing between 25 to 75 carbon atoms and preferred amounts are in the range of 10% to 80% by weight of the total amount of reactants. The adhesive compositions were found to produce a fast bonding of the calcified tissues, with a joint strength of above 0.5 N/sq.mm.

Abstract: A dressing includes a stable, tacky gel of polyurethane and poly(N-vinyl lactam), the poly(N-vinyl lactam) having a K-value of at least about 60 and mole equivalents of acid groups above 1.4. The dressing may also include a substrate and various additives incorporated with the gel.

Abstract: A polyetherimide suture exhibits excellent properties such as resistance to creep, great knot security and physical stability. The suture may be monofilament or multifilament, and methods of making and using the suture are disclosed.

Abstract: Catalyzes methods and curable compositions involving amino-ester catalysts and isocyanate-functional materials. Also disclosed are casting articles and methods of orthopedic casting.

Abstract: Polycarbophil or crosslinked acrylic acid polymer is prepared in a solvent selected from acetone, alkyl acetates, and mixtures thereof, in the presence of an effective amount of divinyl glycol crosslinker, and in the presence of an effective amount of a suitable initiator allowing for polymerization to proceed at a temperature below 100.degree. C. at atmospheric pressure. The polymer produced has average particle size of less than 10 microns without grinding, its viscosity is greater than about 20,000 cPs when measured in water at 1% concentration, and it adheres to mucous membranes. By preparing the polymer in a non-aqueous solvent, the need for aqueous washing is avoided and the subsequent and enormous swelling of the polymer is avoided which means that prolonged and excessive drying inherent in the known processes is avoided.

Abstract: A novel topical medicinal composition is described which comprises a copolymer which has both pendant fluorochemical groups and pendant polysiloxane grafts.

Abstract: The invention relates to a process for the preparation of acrylate-based pressure-sensitive hot-melt adhesives by irradiation on a substrate, characterized in thata) at least one acrylic monomer is copolymerized with N-tert.-butylacrylamide (TBA), whereinb) the reaction mixture (of a) to be polymerized can additionally contain one or more ethylenically unsaturated compounds which do not belong to the group of acrylic monomers of a),c) the resulting solid polymer is heated and is applied in a form which is capable of flowing or a liquid form to a substrate, it being possible for the compositions of steps a) to c) to contain additives and auxiliaries if appropriate, andd) the coated substrate is irradiated with high-energy radiation.

Abstract: A composition and a method for coating a wound is described. The composition consists of a mixture of 20 parts by weight of polyether polyurethane resin pellets being dissolved in about 80 parts by weight of tetrahydrofuran thereafter mixing the solution in order to provide complete mixing in an air tight container. The composition then being applied to a wound to form a tough but elastic wound coating to promote healing of animal tissue.

Abstract: Crosslinked hydrogel polymers are made by reacting a disubstituted aliphatic diamine of the general formula (I) or (XI) as given in the specification, with one or more diepoxides having the general formula (II), also as given in the specification, and subjecting the resulting non-crosslinked polymer having repeating units of the formula III or XIII to crosslinking conditions to produce the desired crosslinked hydrogel polymer. Hydrogel polymers thus produced are highly hydrophilic with a high degree of water uptake and a high equilibrium water content. In addition, these hydrogel polymers are highly absorptive of fluids and are adhesive when applied to dry surfaces but not when applied to wet surfaces. The hydrogel polymers are useful in wound dressings.

Abstract: A self-adhesive bandage is provided. The bandage comprises a substrate having a first side and a second side and a plurality of layers including a backing layer which forms the first side of the substrate, and an adhesive layer which forms the second side of the substrate. A hydrogel layer is disposed over the second side of the substrate and is made from a polyurethane hydrogel material especially suitable for absorbing bodily fluids, such as wound exudate. Additionally, a plurality of support layers may be interposed between the substrate and the hydrogel layer to provide the bandage with additional support.

Abstract: A dressing includes a stable, tacky gel of polyurethane and poly(N-vinyl lactam), the poly(N-vinyl lactam) having a K-value of at least about 60 and mole equivalents of acid groups above about 1.4. The dressing may also include a substrate and various additives incorporated with the gel.

Abstract: A wound dressing for a deep wound is provided. The wound dressing comprises a hydrogel layer having an upper surface and a lower surface. The hydrogel layer is correspondingly sized to fill the cavity of the deep wound. The wound dressing further comprises a dressing removal layer disposed between the upper surface and the lower surface of the hydrogel layer. The dressing removal layer extends outwardly from the hydrogel layer so as to form a pull tab which facilitates removal of the hydrogel layer from the deep wound. A method of making a wound dressing for a deep wound is also provided.

Abstract: There is disclosed a composition useful for medicated treatment of hooves of live animals. The composition comprises a major portion of a carrier and hoof penetrant, a minor amount of a filler comprising chiefly polyolefin fibers, and an oil-in-water emulsifier to form a staple composition. The composition can include optional quantities of a medicinal compound. A specific example of the compound comprises approximately 12 weight percent of chopped fibers of a polyolefin such as polyethylene or polypropylene, about 69 percent of a carrier comprising pine tar, paraffin wax and coconut oil, and an oil-in-water emulsifier such as an aliphatic alcohol or alkyl glucose fatty acid ester. Preferably, the composition also includes a medicinal compound such as alcohol, iodine or a soluble iodide. The method comprises packing the hooves of live animals such as horses with the composition.

Abstract: A dressing material for the treatment of wounds comprises a dressing and corpuscles which are placed on or may be placed on the dressing, most frequently by means of an irreversible adhesive connection, and which contains at least one substance which is active in wound care. The corpuscles consist of a solid, continuous, hydrophobic, biologically inert, water-insoluble matrix which is stable at temperatures below 50.degree.C. and which contains at least one hydrophilic, discontinuous phase in which one or more biologically active substances are dispersed, dissolved or are present as a coating thereon. As active substances may for example be used EGF (epidermal growth factor) EGF-urogastron, immunoglobulines, antiseptics, antibiotics, antiinflammatory agents, proteolytics and local anaesthetics, heparin and vasodilators.

Abstract: The invention relates to a wound secretion absorbing hydrogel of the following composition:a) 20 to 70%-wt of at least one multivalent alcoholb) 10 to 35%-wt of at least one natural thickener (biopolymer)c) 0.05 to 12%-wt of at least one uncross-linked copolymer of one or more vinylcarboxylic acids and their salts (synthetic polymer)d) 0.05 to 10%-wt of a cross-linking agente) 0 to 50%-wt of water or physiological salineas well as to the use of this hydrogel as wound dressing.

Abstract: The invention provides a method of synthesizing a copolymer of two .alpha.-amino acids which comprises the preparation of an N-carboxyanhydride of a first .alpha.-amino acid and the N-carboxyanhydride of a second .alpha.-amino acid, followed by the copolymerization of this mixture. The mixture is obtained by the reaction of phosgene with a mixture of a first and the second .alpha.-amino acids, the amino acids having similar reaction rates with phosgene. It also relates to the copolymer obtained by implementation of this method and an agent for covering skin wounds comprising this copolymer.

Abstract: A method of using a pressure sensitive adhesive to form a moisture resistant, water-dispersible tape is provided. The adhesive and tape are resistant to autoclavation conditions and/or moisture and body fluids during usage, and are water-dispersible when immersed in aqueous solutions. The tape may be used with cloth body coverings, such as garments such as hospital gowns, drapes, dressings, diapers and other body coverings which require cloth to cloth or cloth to skin adhesion in the presence of moisture and bodily fluids yet be dispersible from such body coverings during laundering or other aqueous alkali immersion.