Abstract: The present invention provides a dental paste, a dental article, methods of making and using the dental paste, and compositions prepared therefrom. In one embodiment, the dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-aggregated primary silica particles, with the fillers being dispersed in a hardenable resin.

Abstract: A one-part self-etching and bonding dental resin composition comprising in combination about 10 to about 30 weight percent of a polymerizable (meth)acrylate carboxylic acid/anhydride, based on the total weight of the polymerizable components in the composition; a copolymerizable multi-functional (meth)acrylate resin; a copolymerizable diluent monomer; and a curing system. The composition has the advantage of not requiring a separate etching and bonding step.

Abstract: A material contains at least a polymerizable N,O-functionalized acrylic acid hydroxyamide of the Formula (I) in which A is an n+m-valent linear or branched aliphatic C1 to C50 radical, in which the carbon chain can be interrupted by O, S, —CO—O—, CO—NH, O—CO—NH or NH—CO—NH, an n+m-valent aromatic C6 to C18 radical or an n+m-valent cycloaliphatic or heterocyclic C3 to C18 radical, wherein the radicals can carry one or more substituents, Y is not present, or is O, S, an ester, amide or urethane group, R1 is hydrogen, an aliphatic C1 to C20 alkyl or C3 to C8 cycloalkyl radical which can carry one or more substituents, R2 is H or a C1 to C10 alkyl radical, R3 is not present or is a C1 to C16 alkylene radical which can be interrupted by O, HG is not present, is —COOH, —P?O(OH)2; —P?O(OH)(OR4); —O—P?O(OH)2, —SO2OH or —O—P?O(OH)(OR4), R4 is a C1 to C15 alkyl radical, phenyl or benzyl radical and n is a number from 1 to 5 and m a number from 0 to 3.

Abstract: A flowable, light-curing underfilling material that is easily visible and distinguishable from the tooth substance. The underfilling material contains at least one polymerizable monomer, at least one polymerization initiator and also 0.3-10% white pigment.

Abstract: Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and crosslinking in situ. Methods for making the resulting biocompatible crosslinked polymers biodegradable or not are provided, as are methods for controlling the rate of degradation. The crosslinking reactions may be carried out in situ on organs or tissues or outside the body. Applications for such biocompatible crosslinked polymers and their precursors include controlled delivery of drugs, prevention of post-operative adhesions, coating of medical devices such as vascular grafts, wound dressings and surgical sealants. Visualization agents may be included with the crosslinked polymers.

Abstract: An aqueous one-pack self-etching and self-priming dental adhesive composition having a pH of at most 2, which comprises: (i) a polymerizable N-substituted alkylacrylic or acrylic acid amide monomer which optionally contains an inorganic acidic moiety selected from a phosphonic acid moiety or a sulfonic acid moiety, and (ii) a curing system.

Abstract: Compositions, methods, and kits are provided for sealing applications. Compositions are prepared by combining a first cross-linkable component with a second cross-linkable component to form a porous matrix having interstices, and combining the porous matrix with a hydrogel-forming component to fill at least some of the interstices. The compositions exhibit minimal swelling properties.

Abstract: The present application relates to a dental primer adhesive system that is capable of being used as either a one-step or two-step self-etch dental primer and is compatible with self-cure composites and dual-cure composites with reduced permeability.

Abstract: The present invention provides hydrogels formed from polyurethane (meth)acrylates in water using water-soluble redox initiators.

Abstract: A novel composition-of-matter, method of manufacturing thereof, and applications thereof as an adhesive, in a wide variety of different fields, and in particular, in the health care fields of medicine, dentistry, and veterinary science, for use by health care providers, such as medical, dental, and veterinary, surgeons, in procedures for reattaching or repairing body parts or components thereof, such as tissue, of (human or animal) subjects, especially under wet conditions, for example, involving adhesion of wet surfaces. The composition is comprised of a cross-linked form of a water miscible polymer, and at least one phloroglucinol type compound selected from the group consisting of: phloroglucinol, a derivative of phloroglucinol, and a polymer synthetically prepared from phloroglucinol or a derivative of phloroglucinol. An exemplary water miscible polymer is a naturally existing, or synthetically prepared, salt form of the carbohydrate alginic acid, such as sodium alginate, or alginic acid itself.

Abstract: The present invention provides a dental paste, a dental article, methods of making and using the dental paste, and compositions prepared therefrom. In one embodiment, the dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-aggregated primary silica particles, with the fillers being dispersed in a hardenable resin.

Abstract: Ceramic filler compositions of customized shapes (FIGS. 1-30) according to the present invention, includes ceramic and glass-ceramic particles having a customized shape which provides mechanical locking within a resin matrix giving significantly improved fracture toughness performance for a resin/glass or ceramic composite system. The material has particular application as a tooth filling material with significantly improved wear resistance. The wide range of unique-shaped filler particles are produced using wet chemistry methods according to the invention of preparing the ceramic particles for use in a resin matrix composite material. Such composite materials have a very wide application, especially as a dental composite filling material for restoring a tooth.

Abstract: A cationically curable composition for dental use containing a cationic polymerization initiator (I) and cationically polymerizable monomers (II), the cationically polymerizable monomers (II) containing an oxetane compound and an epoxy compound or an alkenyl ether compound at a ratio of amounts that satisfy the conditions expressed by the following formula, (a×A):(b×B)=91:9 to 45:55 wherein A is a mol number of the oxetane compound, “a” is an average number of the oxetane functional group contained in one molecule of the oxetane compound, B is a mol number of the epoxy compound or the alkenyl ether compound, and “b” is an average number of the epoxy functional group contained in one molecule of the epoxy compound or an average number of the alkenyl ether functional group contained in one molecule of the alkenyl ether compound.

Abstract: The present invention features ionomer compositions containing nanofillers. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Abstract: A method of using a shelf-stable two-part self-adhering dental composition that comprises (a) at least one acidic compound containing at least one acidic moiety selected from the group consisting of where R is an alkyl or aryl group; (b) at least one polymerizable monomer without any acidic group where the polymerizable group is selected from the group consisting of an acrylate, a methacrylate and a vinyl group; (c) a substituted thiourea selected from the group consisting of 1-(2-pyridyl)-2-thiourea and 1-(2-tetrahydrofurfuryl)-2-thiourea; and (d) a hydroperoxide compound with at least one hydroperoxide group attached to a tertiary carbon. The first and second parts are then mixed immediately prior to application, applied to a dental substrate, and hardened. The bond strength of the mixed composition to dentine substrate is at least 3 MPa. The composition has excellent shelf-life and is self-adhering to various dental substrates such as a tooth, metal alloy and porcelain.

Abstract: A mouldable pressure-sensitive hydrocolloid adhesive composition, particularly useful as a medical adhesive, comprising a dispersion of a discontinuous phase of one or more water-soluble and/or water swellable absorbent polymers in a continuous phase comprising a thermoplastic elastomer, a compatible liquid rubber, a polyisobutylene and a low-molecular weight polybutene.

Abstract: A denture liner which includes a hydrophobic polymer component, a plasticizer component and an adhesive component. A method for making this denture liner and a denture liner kit are also provided. The compositions have improved consistency and are useful in prosthodontics, including formulating denture liners for the compositions have a glass transition temperature lower than the lower of an ambient temperature at which the liner is applied and a temperature inside the oral cavity. Phthalate-free embodiments, as well as kits are also described.

Abstract: There is provided a highly functional one-step light-curing dental adhesive composition i) based on a multifunctional prepolymer mixture of 2,2-bis-[4-(2-hydroxy-3-methacryloyloxypropoxy)phenyl]propane (“Bis-GMA”) and a multifunctional prepolymer formed by substitiuting hydrogen atoms of hydroxyl groups present in Bis-GMA molecules with methacrylate groups, in which the Bis-GMA is used as a base prepolymer of conventional dental adhesive compositions; and ii) comprising and acidic monomer for removing a portion of smear layer, which is allowed to be bonded without separate treatment of acid etchant, an adhesive monomer having both hydrophobic and hydrophilic properties, a hydrophilic monomer which is allowed to be bonded in the present of moisture, an inorganic filler for improving mechanical properties, diluent, water for demineralization, a photoinitiation system and other additives.

Abstract: A method for convenient, controlled wound closure of an eye, the skin, internal organs and other soft tissue which comprises administering to the wound a sterile, body compatible photopolymerizable acrylate or methacrylate adhesive, and exposing the applied adhesive to light.

Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.

Abstract: A one-part, self-etching dental adhesive having improved performance such as adhesion performance with a simple one-coat application, without the need of separate acid-etching, a priming pre-treatment, or bonding step. The invention provides such improvements due to a function of the pH balance of the system in combination with an acid stable photoinitiating system. More specifically, the performance and pH balance is achieved through the employment of a hydrolytically stable, acidic, high-strength adhesive monomer (such as PENTA), with a stable, bifunctional, hydrophilic monomer (such as AHPMA) that yields greater crosslinking.

Abstract: A two-part self-curing endodontic sealing system comprises a thiourea derivative, such as acetyl thiourea, and a hydroperoxide, such as cumene hydroperoxide. The thiourea derivative is used as a reducing agent and the hydroperoxide is used as an oxidizing agent.

Abstract: This invention relates generally to compositions and systems for forming biomaterials containing a transient colorant for visualizing tissue or surgical materials coated with such biomaterials, to methods of using such compositions as bioadhesives, for tissue augmentation, in the prevention of surgical adhesions, for coating surfaces of synthetic implants, as drug delivery matrices, for ophthalmic applications, and in other applications.

Abstract: Polymerizable compositions and methods are provided that include an ethylenically unsaturated compound and an arylsulfinate salt. The polymerizable compositions are useful as hardenable dental compositions.

Abstract: A visible light cationically photopolymerizable composition is provided. This composition includes an expanding monomer and a dioxirane. More specifically, the expanding monomer used in this composition is one or more dioxiranyl tetraoxaspiro[5.5]undecanes. The composition of the present invention may be used as a matrix resin for dental restorative materials. Another embodiment of the present invention is various novel dioxiranyl tetraoxaspiro[5.5]undecanes.

Abstract: A self-etching, priming dental adhesive composition comprises an olefinically unsaturated monomer having an —SO3 functionality; a copolymerizable multi-functional (meth)acrylate adhesive; and a curing system. The self-etching, priming dental adhesive may further comprise a copolymerizable adhesion promoter containing an acid functionality, the adhesion promoter being different from the olefinically unsaturated monomer having an —SO3 functionality and the copolymerizable multi-functional (meth)acrylate adhesive, and a solvent system in an amount effective to dissolve the adhesive and/or the adhesion promoter. The adhesive composition provides even further advantages over the art, as all etching, priming, and application of an adhesive can be performed in one step.

Abstract: The invention relates to a method for the production of an adhesive and an adhesive kit for joining similar or different metal surfaces or ceramics, especially in the field of biomedicine. The objective of the invention is to avoid polymerization-linked by-products and disadvantageous effects, in addition to enabling a temporary biocompatible bond between metal and metal or metal and ceramics. The inventive method consist in using a monomer-free polymethylmethacrylate which is mixed with a suitable, non-toxic solvent and a bioactive vitreous-crystalline material with a particle size ranging from 0.05–20?, consisting of 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to an adhesive kit consisting of said components.

Abstract: A method for providing a dental composition comprising providing a paste/paste two-part self-adhering dental composition comprising (a) at least one acidic compound containing at least one acidic moiety selected from the group consisting of where R is an alkyl or aryl group; (b) at least one polymerizable monomer without any acidic group where the polymerizable group is selected from the group consisting of an acrylate, a methacrylate and a vinyl group; (c) at least one finely divided filler; (d) a reducing agent; and (e) an oxidizing agent; and providing instructions for mixing the two pastes immediately prior to application where the ratio of a first paste containing (a) or a higher concentration of (a) to a second paste not containing (a) or containing a lower concentration of (a) is greater than 1:1 (by volume). The method also includes mixing the two pastes and applying the mixed composition to a dental substrate.

Abstract: The present invention provides methods of constructing, reinforcing or modifying dental structures. The methods of the present invention include contacting a dental structure with dental resin and a triaxial material. In another aspect, the present invention provides dental structures including a triaxial material.

Abstract: Sealing and filling compositions for use in filling and/or sealing a root canal. The sealer and filler compositions include a polymerizable material that shrinks when polymerized. The composition also includes a gas releasing component that at least partially offsets the shrinkage caused by polymerization of the polymerizable material. The gas releasing component offsets polymerization shrinkage by creating tiny gas bubbles in the polymeric material, which causes expansion. The gas releasing component can be an acid and a base such as citric acid and sodium bicarbonate, which when mixed give off carbon dioxide. The composition can also include a dispersing agent to disperse the gas bubbles throughout the composition.

Abstract: The present invention provides a hardenable (i.e., curable by polymerization, crosslinking, ionic, or other chemical reaction) composition that includes polymerizable urea or thiourea compounds that function as reductants (i.e., reducing agents) in redox polymerization reactions.

Abstract: A polymerisable dental filling and sealing composition is provided which comprises a mixture of at least one resin containing on average at least two acrylate or methacrylate groups and a copolymerisable methacrylate or acrylate monomer, which has a low viscosity compared with said resin, the copolymerisable monomer being present in an amount such that the composition can be introduced by syringing into a cavity having a diameter of less than 1 mm.

Abstract: The present invention features ionomer compositions containing nanofillers. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Abstract: A visible light photopolymerizable composition comprising a) an aryliodonium salt and b) an acylphosphine oxide compound. These compositions can be used together with an epoxy resin as a dental composition.

Abstract: The present invention provides a one-bottle dental bonding composition that provides a bonding layer excellent in bonding strength, independent of the skill of the practitioners, and, more preferably, that releases fluoride ion gradually into oral cavity over an extended period of time. The one-bottle dental bonding composition comprises a radical polymerizable monomer (A) having an acidic group in the molecule, another radical polymerizable monomer (B), a photopolymerization initiator (C) and a water-soluble organic solvent (D), and is substantially free of water.

Abstract: The present invention provides a dental paste, methods of making and using the dental paste, and compositions prepared therefrom. The dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-agregated primary silica particles, with the fillers being dispersed in a hardenable resin. Fillers including porous, non-pyrogenic silica, and methods of making and using the fillers, are also provided.

Abstract: This invention relates to the kit of parts containing (co)polymers having hydrogen-siloxane groups, a catalyst, a vinyl compound and a hydrosilyl compound. The kits of parts may be used as permanent or temporary, soft or hard elastic, bonding or filling materials on a dental substrate or a bone substrate.

Abstract: Dental composite formulations containing an initiator and a multiacrylate compound are disclosed. The formulations lack methyl methacrylate, a volatile, irritating, and potentially hazardous material commonly found in dental formulations. The multiacrylate compound has at least three acrylate functionalities per molecule. The formulations cure to form a surface lacking an oxygen inhibition layer. The formulations can be used as dental sealants, dental coatings, and in fingernail/toenail repair applications.

Abstract: The invention relates to iminooxadiazine dione derivatives with the formula (I) in which X, Y and Z represent a (meth)acrylic acid radical of the formula (II) in which R1 is hydrogen, an aliphatic hydrocarbon radical with 1 to 14 carbon atoms, which can be interrupted by oxygen atoms, or an aromatic hydrocarbon radical with to 16 carbon atoms; R2 is hydrogen, an aliphatic hydrocarbon radical with 1 to 5 carbon atoms or an aromatic hydrocarbon radical with 6 carbon atoms, n is 1 or 2; where the (meth)acrylic acid radical of formula (II) is bound to the radical of formula (I) by R1 or R2 and the binding point remaining at R2 or R1 is saturated by hydrogen and X, Y and Z can be the same or different; the individual radicals R being able to be the same or different and selected from alicyclic or aromatic hydrocarbon radicals with 5 to 10 or aliphatic hydrocarbon radicals with 1 to 10 carbon atoms.

Abstract: A dental adhesive containing an acidic group-containing radically polymerizable monomer, a non-acidic radically polymerizable monomer, a chemical polymerization initiator and a filler, as well as a 2,4-diphenyl-4-methyl-1-pentene. When the dental adhesive is used for adhering a crown restorative to the tooth, an excess of cement swelling from the surface of adhesion can be favorably removed, the curing time can be suitably adjusted without decreasing the strength of adhesion to the tooth, and a change in the color tone of the cured body can be effectively suppressed.

Abstract: The invention relates to uses of glasses and glass-ceramics in dental and orthodontic applications.

Abstract: Stable self-etching copolymerizable primer compositions are provided including compounds having a polymerizable ethylenically unsaturated groups and acidic groups, and optionally comonomers and suitable solvents. Such compositions are used in conjunction with dental adhesives to provide one or multi-component dental systems capable of etching or decalcifying tooth dentin and enamel without the need for a separate rinse step. Methods of use of such compositions according to the present invention include application for priming and imparting enhanced adhesion between the primers, adhesives, and the tooth substrates such as dentin or cut or uncut enamel, and subsequently applied dental composites, restoratives or other dental components.

Abstract: One embodiment of the invention provides a dental cement composition which includes (a) an acid group-having polymerizable monomer, (b) a polyalkenoic acid, (c) an ion-leachable glass filler, (d) a polymerizable monomer not having an acid group, (e) water, (f) a peroxide, (g) a salt of an aromatic sulfinic acid, and (h) an aromatic secondary amine and/or an aromatic tertiary amine.

Abstract: An ionomer composite composition having improved and unique physical properties, includes a glass material containing at least one of divalent cations and multivalent cations; and at least one copolymer. The copolymer comprises: at least one hydrophilic monomer containing acid functional groups adapted to react with the at least one of divalent cations and multivalent cations to form ionic crosslinks among polymer chains, the hydrophilic monomer present in an amount sufficient to impart a desired degree of aqueous solubility to the copolymer, and at least one hydrophobic monomer present in an amount sufficient to impart a desired degree of structural stability to the composite composition when exposed to an aqueous environment.

Abstract: Dental material containing an amide of the general formula BXn in which B stands for a hydrocarbon radical with 1 to 5 carbon atoms, which can contain one or more of the groups O, S, NH, CO—NH, O—CO—NH and/or NH—CO—NH, and which is substituted n times with the group X, X stands for the group which is bound via the nitrogen atom or via C-2 to the radical B, the bond site not connected to B carrying a radical R2, R1 being hydrogen, an alkyl group with 1 to 20 carbon atoms or a phenyl radical, two or more radicals X being able to share a radical R1 and R1 also being able to be a constituent of the radical B, R2 being hydrogen, an alkyl group with 1 to 20 carbon atoms or a phenyl radical, and n being a number from 2 to 5.

Abstract: The invention relates to a redox initiator system which allows dental formulations to be cured in acidic medium by way of a free-radical polymerization and which ensures a high level of adhesion of the polymerizing composition to the hard substances of the teeth, namely enamel and, in particular, dentine. The redox initiator system comprises the following constituents: (A) from 14.9 to 50% by weight of a barbituric acid or thiobarbituric acid and/or of a barbituric or thiobarbituric acid derivative, (B) from 30 to 75% by weight of a peroxodisulfate compound and/or peroxodiphosphate compound, (C) from 10 to 35% by weight of a sulfinic acid compound, and (D) from 0.1 to 5% by weight of a copper compound.

Abstract: Dental resin cement materials having unique handling properties are provided that comprise a) filler, b) polymerizable resin, and c) a polymeric handling modifier that is dispersed in the polymerizable resin at 25° C. and that has a molecular weight of between about 500 and 100,000. Components a) b) and c) are present in an amount effective to achieve a Viscosity vs Shear Rate Curve that fits a power law model of F(x)=AxB. The correlation value of the material to this curve is greater than 0.85 for both the increasing and decreasing shear rate curves, and the value of B is less than about ?0.01. Resin cements are also provided that comprise acid functionality and water, but which do not comprise an acid reactive filler. Such cements may be self etching, thereby avoiding the need to carry out a separate acid etch step.

Abstract: An adhesive composition comprising (a) an acidic group-containing polymerizable monomer; (b) a polymerizable monomer represented by the general formula (I): wherein R1 is hydrogen atom or methyl group; R2 is a halogen atom, hydroxyl group, mercapto group or —O—R3—OH group, wherein R3 is an alkylene group having 6 to 25 carbon atoms; and Y is oxygen atom or sulfur atom; and (c) a hydrophilic polymerizable monomer, wherein the weight ratio of the polymerizable monomer (b)/acidic group-containing polymerizable monomer (a) is 0.001 to 0.5. The adhesive composition of the present invention can be suitably used for bonding a hard tissue with a resin material in the medical field and the dental field.

Abstract: A dental polymerizable and curable composition that can be used as a dental composite restorative featuring excellent handling property at the time of filling, a small contraction upon polymerization, a high bending strength, excellent surface smoothness and wear resistance, and a very good matching of color tone to the natural tooth after restored.

Abstract: A dental composition comprising a silver-containing ceramic having antimicrobial and color stabilizing properties and methods for using the composition. The composition comprises a silver-containing glass powder or a silver-containing zeolite powder, at least one monomer having at least one ethylenically unsaturated group, and a polymerization initiator system. Other components, such as a filler, may also be included. The inventive composition possesses antimicrobial properties and exhibits excellent mechanical properties upon curing. Additionally, when the polymerization initiator is a two-part redox initiator system, the composition has improved color stability. The inventive composition can be used as a dental restorative composition, an endodontic composition, an orthodontic composition, and/or a prosthetic composition.