Sulfur Containing Patents (Class 536/118)
  • Patent number: 4470976
    Abstract: Poly-cation salts of 4-O-polyhexaose-thio-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: September 11, 1984
    Assignee: American Cyanamid Company
    Inventors: Thomas G. Miner, Robert E. Schaub, Seymour Bernstein
  • Patent number: 4468385
    Abstract: Poly-cation salts of 4-O-polyhexaose-thio-alkylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: August 28, 1984
    Assignee: American Cyanamid Company
    Inventors: Francis M. Callahan, Thomas G. Miner, Seymour Bernstein
  • Patent number: 4443486
    Abstract: A stabilizer for milk products comprised of a carrageenan extractive of Eucheuma cottonii seaweed having a water viscosity at 1.5% concentration and 75.degree. C. of not less than 5 mPa.s and not more than about 20 mPa.s.
    Type: Grant
    Filed: March 11, 1981
    Date of Patent: April 17, 1984
    Assignee: FMC Corporation
    Inventor: Kenneth B. Guiseley
  • Patent number: 4440758
    Abstract: Poly-cation salts of bis(or tris)[4-O-monohexose-oxy]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: April 3, 1984
    Assignee: American Cyanamid Company
    Inventors: Janis Upeslacis, Robert E. Schaub, Seymour Bernstein
  • Patent number: 4435387
    Abstract: Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: March 6, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Patent number: 4431638
    Abstract: Poly-cation salts of bis(or tris)[4-O-monohexose-thio]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Patent number: 4431636
    Abstract: Poly-cation salts of bis (4-O-polyhexaose-thio)-phenyl urea sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Patent number: 4431637
    Abstract: Poly-cation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Janis Upeslacis, Robert E. Schaub, Seymour Bernstein
  • Patent number: 4407796
    Abstract: Poly-cation salts of bis-(or tris-) [polyhexaose-thio (or sulfinyl, or sulfonyl)]-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: October 4, 1983
    Assignee: American Cyanamid Company
    Inventors: Thomas G. Miner, Seymour Bernstein
  • Patent number: 4404365
    Abstract: Bis-[.beta.-D-glucopyranosyl-1-thio (or sulfinyl or sulfonyl)]-arylene sulfate derivatives, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation of such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: September 13, 1983
    Assignee: American Cyanamid Company
    Inventors: Thomas G. Miner, Seymour Bernstein
  • Patent number: 4404195
    Abstract: N,N'-Bis[4-[(2,3,4,6-tetra-O-sulfo-.alpha.(or .beta.)-D-glucopyranosyl)thio(or oxy)]phenyl]alkyl diamides, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation of such intermediates and end products.
    Type: Grant
    Filed: April 16, 1982
    Date of Patent: September 13, 1983
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Patent number: 4402944
    Abstract: Polysulfonated Sennoside A and B derivatives, useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: September 6, 1983
    Assignee: American Cyanamid Company
    Inventors: Francis M. Callahan, Seymour Bernstein
  • Patent number: 4399126
    Abstract: N,N'-Bis[4-[2,3,6,-tri-O-sulfo-4-O-(2,3,4,6-tetra-O-sulfo-.alpha.(and .beta.)-D-glucopyranosyl)-.alpha.(and .beta.)-D-glucopyranosylthio or sulfinyl or sulfonyl]phenyl]alkyldiamides and alkyldiamines, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: April 16, 1982
    Date of Patent: August 16, 1983
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Patent number: 4389523
    Abstract: A cellulose sulfate salt having a heparinic action is provided, which satisfies requirements of 0.8.ltoreq.<<F>>.ltoreq.2.6, <<f.sub.2 >>.gtoreq.<<f.sub.3 >> and <<f.sub.2 >>.gtoreq.<<f.sub.6 >> wherein <<f.sub.2 >>, <<f.sub.3 >> and <<f.sub.6 >> stand for probability of substitution of atoms H in the OH groups bonded to the C.sub.2, C.sub.3 and C.sub.6 positions of the glucopyranose ring unit by sulfuric acid radicals, respectively, and <<F>> stands for the total substitution degree which is the sum of <<f.sub.2 >>, <<f.sub.3 >> and <<f.sub.6 >>. The cellulose sulfate salt is prepared by reacting a cellulose having a crystal form I with an SO.sub.3 /amine or SO.sub.3 /amide complex in an amount of 2 to 4 mole equivalents per glucose unit of the cellulose at -10.degree. C. to 40.degree. C.
    Type: Grant
    Filed: November 25, 1981
    Date of Patent: June 21, 1983
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Kunihiko Okajima, Kenji Kamide, Toshihiko Matsui
  • Patent number: 4374832
    Abstract: Poly-cation salts of bis- (or tris-) (polyhexaose-oxy)-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: February 22, 1983
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4374831
    Abstract: Bis-(.beta.-D-glucopyranosyl-1-oxy)-arylene sulfate derivatives, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation of such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: February 22, 1983
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4359459
    Abstract: O-.alpha.-D-Galactopyranosyl(1.fwdarw.6)-O-.alpha.-D-galactopyranosyl(1.fwd arw.6)-O-.alpha.-D-glucopyranosyl(1.fwdarw.2)-O-.beta.-D-fructofuranosyl(1. fwdarw.6)-O-.alpha.-D-glucopyranosyl(1.fwdarw.4)-O-.alpha.-D-glucopyranosyl -.alpha.-D-glucopyranoside sulfate salts useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4359460
    Abstract: 6'-(1-Adamantanecarboxylate)-6-O-.alpha.-D-galactopyranosyl-.alpha.-D-gluco pyranose sulfate salts, useful as complement inhibitors, and the process for making such compounds.
    Type: Grant
    Filed: October 13, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4359458
    Abstract: O-.beta.-D (and O-.alpha.-D) multi-galactopyranosyl (or xylopyranosyl or glucopyranosyl) 1.alpha.,1.alpha.' galactopyranosyl (or xylopyranosyl or glucopyranosyl) sulfate salts, useful as complement inhibitors, the intermediates thereof and the process for preparation of such compounds.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Arthur J. Lewis, Seymour Bernstein
  • Patent number: 4359461
    Abstract: Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts, useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: October 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4357326
    Abstract: O-.alpha.-D-glucopyranosyl(1.fwdarw.4)-[O-.alpha.-D-glucopyranosyl-(1.fwdar w.4)].sub.n -O-.beta.-D-glucopyranosyl(1.fwdarw.6)-.beta.-D-fructofuranosyl-O-.alpha.- D-galactopyranosyl(1.fwdarw.6)-.alpha.-D-glucopyranoside sulfate salts, useful as inhibitors of the complement system and the process of making such compounds.
    Type: Grant
    Filed: August 28, 1981
    Date of Patent: November 2, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4353889
    Abstract: Analogs of the glycoside rebaudioside A are disclosed. These materials have the formula ##STR1## wherein R is a simple physiologically acceptable noncarbohydrate polar organic group. The analogs are sweet and find use as sweeteners.
    Type: Grant
    Filed: June 11, 1981
    Date of Patent: October 12, 1982
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4342752
    Abstract: Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: August 3, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, John F. Poletto, Seymour Bernstein
  • Patent number: 4342753
    Abstract: Carboxyalkyl derivatives of rutin polyl(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: August 3, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, John F. Poletto, Seymour Bernstein
  • Patent number: 4337249
    Abstract: N-(4-O-.alpha.-D-glucopyranosyl-.beta.-D-glucopyranosyl)-3,4-dihydroxycinna mamide, nonakis (H-sulfate) (nonaester), nona-alkali metal or alkaline earth metal-salts, useful as modulators of the complement system, the intermediates thereof and the process of making such salts and intermediates.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: June 29, 1982
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Patent number: 4334058
    Abstract: Rutin poly(H--)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: June 8, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4321364
    Abstract: A chromogenic substrate for the assay of polysaccharide endo-hydrolases is the reaction product of a polysaccharide susceptible to endo-hydrolase degradation, a chemical reagent for increasing the solubility of the polysaccharide so as to increase its susceptibility to enzyme degradation, and a dye substance for coloring the polysaccharide and rendering it capable of estimation by absorption spectrometry. The amount of chemical reagent should be such as to produce a degree of chemical substitution in the range 0.06 to 0.6 DS.
    Type: Grant
    Filed: April 17, 1980
    Date of Patent: March 23, 1982
    Assignee: Minister for Public Works for the State of New South Wales
    Inventor: Barry V. McCleary
  • Patent number: 4304904
    Abstract: D-Erythro-2,3-dihydroxy-1-(and 3-) (1-phenyl-1H-pyrazolo[3,4-b]quinoxalin-3-yl)propyl-.beta.-D-glucopyranosid e (and .alpha.-D-galactopyranoside) poly(H-sulfate)salts useful as complement inhibitors.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: December 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4304903
    Abstract: D-Erythro-2,3-dihydroxy-1-[substituted and unsubstituted)-1-phenyl-1H-pyrazolo[3,4-b]quinoxalin-3-yl]propyl-4-O-.alph a.-D-glucopyranosyl-.alpha.-D-glucopyranoside poly(H-sulfate)salts useful as complement inhibitors.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: December 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4302577
    Abstract: An improved process or method for the preparation of pharmaceutical grade biologically and physiologically "active" chondroitin sulfate, predominantly chondroitin sulfate A, chondroitin sulfate C, and mixtures thereof from source material comprising forming a solution from the source material containing said "active" material, adding thereto a complexing agent to form a precipitate which is a water insoluble complex of the active material and the complexing agent, and breaking said complex to recover the pharmaceutical grade "active" material.
    Type: Grant
    Filed: February 4, 1980
    Date of Patent: November 24, 1981
    Assignee: Biomed Research Inc.
    Inventor: Perry G. Rucker
  • Patent number: 4272526
    Abstract: The present invention relates to a chloral derivative having the general formula ##STR1## in which Y' is a polysaccharide consisting of a chain of anhydroglucose, modified anhydroglucose or uronic acid units as substituent group and in which R is selected from --H, --COCH.sub.2 OH, --[(CH.sub.2).sub.n 0].sub..chi. --H in which n is 2 to 5 and .chi. is 1 to 7; --CH.sub.2 OSO.sub.2 X' or --CH.sub.2 COOX' in which X' is NH.sub.4 or a single equivalent of a non-toxic metallic cation, --(CH.sub.2).sub.n H where n is 1 to 7, --(CH.sub.2).sub.n (OH).sub..chi. Y where Y is --H or --CH.sub.3 n is 1 to 7, .chi. is 1 to 12 and the --OH groups are attached to any or all of the carbon atoms by substitution and wherein when Y.sup.1 is a chain of unmodified anhydroglucose units, these units have the following configurations:.alpha.-D-glucopyranosyl units having a predominantly 1-4 linkage.beta.-D-glucopyranosyl units having a predominantly 1-4 linkage and/or.beta.
    Type: Grant
    Filed: May 8, 1979
    Date of Patent: June 9, 1981
    Assignee: Macarthys Pharmaceuticals Limited
    Inventors: David E. Simpkins, John B. O. Taylor
  • Patent number: 4258034
    Abstract: Lactobionic acid poly(H-sulfate) and salts thereof, useful as complement inhibitors.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: March 24, 1981
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4247535
    Abstract: Modified cyclodextrin sulfate salts useful as complement inhibitors.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: January 27, 1981
    Assignee: American Cyanamid Company
    Inventors: Arthur J. Lewis, Seymour Bernstein
  • Patent number: 4221907
    Abstract: O-.alpha.-D (and O-.beta.-D) multi-galactopyranosyl (and glucopyranosyl) 1.fwdarw.4 (and 1.fwdarw.6) galactopyranosyl 1.fwdarw.6-.alpha.-D-glucopyranose sulfate salts which are useful as complement inhibitors.
    Type: Grant
    Filed: July 9, 1979
    Date of Patent: September 9, 1980
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4174440
    Abstract: A process for producing ionic pullulan gels which comprises gelation of pullulan by crosslinking and introduction of ionic groups into the resulting pullulan gel, the former comprising reacting pullulan with a bi-functional compound in a solvent in the presence of an alkaline substance, and the latter comprising reacting the resulting pullulan gel with a compound having a carboxyl, sulfonic, phosphoric or amino group in a solvent in the presence of an alkaline substance.
    Type: Grant
    Filed: March 27, 1978
    Date of Patent: November 13, 1979
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Fumio Fujita, Kousuke Fukami, Masanori Fujimoto, Tsuneyuki Nagase
  • Patent number: 4138535
    Abstract: A polysaccharide or polyvinyl alcohol containing a mixture of nitrite ester groups with sulfate or nitrate ester groups with the mixture of ester groups being substantially uniformly distributed among the polymer units of the polysaccharide or polyvinyl alcohol.A nitrite ester of a polysaccharide alcohol having a degree of substitution of less than about 2.0. A nitrite ester of polyvinyl alcohol having a degree of substitution of 1.0 or less.
    Type: Grant
    Filed: April 18, 1977
    Date of Patent: February 6, 1979
    Inventor: Richard G. Schweiger
  • Patent number: 4133948
    Abstract: The invention provides novel compounds of the formula: ##STR1## wherein B is .alpha.- or .beta.- and represents a hydrocarbyl group in which the .alpha.-carbon atom is activated by a suitable blocked or unblocked functional group rendering it susceptible to oxidation. The compounds are useful as intermediates in the preparation of prostaglandins and prostaglandin analogues. The invention also provides a stereospecific method of producing these intermediates.
    Type: Grant
    Filed: April 8, 1976
    Date of Patent: January 9, 1979
    Assignee: Chembro Holdings (Proprietary) Limited
    Inventors: Gerhardus J. Lourens, Johannes M. Koekemoer, Elise M. M. Venter
  • Patent number: 4120953
    Abstract: Novel 2,2', 2"-[s-phenenyltris(sulfonylimino)]tris-[2-deoxy-.alpha.-D-glucopyranose], dodecakis (H-sulfate) compounds and their salts which are useful as inhibitors of the complement system of warm-blooded animals, and the compound 2,2',2"-[s-phenenyltris(sulfonylimino)]tris[2-deoxy-D-glucopyranose] which is a new intermediate for the preparation of the active dodecakis (H-sulfate) compounds.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Vijay Gopalan Nair, Seymour Bernstein
  • Patent number: 4120954
    Abstract: 2,2',2"-[s-Phenenyltris(carbonylimino)]tris-2-deoxy-D-glucopyranose and salts thereof, useful as complement inhibitors.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Joseph Peter Joseph, Seymour Bernstein
  • Patent number: 4115094
    Abstract: Organo-tin sucrose compounds wherein three of the tetravalent tin valences are carbon-tin bonds and the fourth is other than a carbon-tin bond exhibit pesticidal and herbicidal activity of the types comparable to the corresponding parent compounds lacking the sucrose residue but with greatly improved water solubility and occasionally higher activity per mole of tin.
    Type: Grant
    Filed: March 22, 1977
    Date of Patent: September 19, 1978
    Assignee: Research Corporation
    Inventors: Robert Clive Poller, Ann Parkin
  • Patent number: 4105760
    Abstract: Water-soluble local anaesthetic compounds having sustained effect are prepared by reacting a chondroitin derivative with a basic local anaesthetic compound.
    Type: Grant
    Filed: December 15, 1976
    Date of Patent: August 8, 1978
    Inventors: Jozsef Szejtli, Eva Dosa, Edomer Tassonyi, Agoston David, Zsuzsanna Nagy nee Biro
  • Patent number: 4098995
    Abstract: Polygalactosido-sucrose Poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: July 4, 1978
    Assignee: American Cyanamid Company
    Inventors: Vijay Gopalan Nair, Joseph Peter Joseph, Seymour Bernstein
  • Patent number: 4096250
    Abstract: The compounds are tri-substituted phosphinegold(I) 1-thio-.beta.-D-glucopyranosides which have antiarthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis. Of the three substituents on the phosphine one is optionally substituted phenyl and the others are lower alkyl or lower alkoxy.
    Type: Grant
    Filed: February 25, 1977
    Date of Patent: June 20, 1978
    Assignee: SmithKline Corporation
    Inventor: David T. Hill
  • Patent number: 4096327
    Abstract: Modified kappa-carrageenan containing hydroxyalkyl groups each having two to three carbon atoms, the degree of substitution of such groups above the corresponding unsubstituted kappa-carrageenan being from 0.1 to 2.0 meq. per gram, forms aqueous gels exhibiting decreased syneresis and melting point and increased compliancy as compared with the corresponding unmodified kappa-carrageenan. The modified kappa-carrageenan is useful in food products as well as in latex paint.
    Type: Grant
    Filed: January 5, 1977
    Date of Patent: June 20, 1978
    Assignee: FMC Corporation
    Inventor: Kenneth B. Guiseley
  • Patent number: 4096247
    Abstract: A new series of lower alkyl ethers of S-tri-lower-alkylphosphinegold 1-thio-.beta.-D-glucopyranoside has been prepared and found to have anti-arthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: February 16, 1977
    Date of Patent: June 20, 1978
    Assignee: SmithKline Corporation
    Inventor: Ivan Lantos
  • Patent number: 4096249
    Abstract: The compounds are trialkylphosphinegold(I)2,3,4,6-tetra-O-(N-loweralkylcarbamoyl)-1-thio-.be ta.-D-glucopyranosides which have antiarthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: February 16, 1977
    Date of Patent: June 20, 1978
    Assignee: SmithKline Corporation
    Inventor: Ivan Lantos
  • Patent number: 4067969
    Abstract: The novel compounds, 4'-deoxy-daunomycin and 4'-deoxy-adriamycin, as well as derivatives thereof are useful as anti-tumor antibiotics. These compounds are prepared by condensing the corresponding aglycone with a novel trifluoracetyl protected reactive halo sugar which is 2,3,4,6-tetradeoxy-3-trifluoroacetamido-L-threo-hexopyranosyl chloride.
    Type: Grant
    Filed: September 13, 1976
    Date of Patent: January 10, 1978
    Assignee: Societa Farmaceutici Italia S.p.A.
    Inventors: Sergio Penco, Federico Arcamone, Aurelio DI Marco
  • Patent number: 4066829
    Abstract: Malto-dextrin poly(H-)sulfate and salts thereof useful as inhibitors of the complement system.
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: January 3, 1978
    Assignee: American Cyanamid Company
    Inventors: Vijay Gopalan Nair, Joseph Peter Joseph, Seymour Bernstein
  • Patent number: 4035569
    Abstract: Preparation of partially substituted nitrate and sulfate esters of polysaccharides or polyvinylalcohol, their esters containing a mixture of nitrite with sulfate or nitrate groups, aqueous media thickened with such esters, the simultaneous preparation of such esters and alkyl nitrites or such esters and inorganic nitrites or nitrates and resulting products, useful as thickeners, films, fibers and in many other applications.
    Type: Grant
    Filed: March 23, 1976
    Date of Patent: July 12, 1977
    Inventor: Richard G. Schweiger
  • Patent number: RE30459
    Abstract: A polysaccharide or polyvinyl alcohol containing a mixture of nitrite ester groups with sulfate or nitrate ester groups with the mixture of ester groups being substantially uniformly distributed among the polymer units of the polysaccharide or polyvinyl alcohol.A nitrite ester of a polysaccharide alcohol having a degree of substitution of less than about 2.0. A nitrite ester of polyvinyl alcohol having a degree of substitution of 1.0 or less.
    Type: Grant
    Filed: April 26, 1979
    Date of Patent: December 23, 1980
    Inventor: Richard G. Schweiger