Bonded To Triazine Ring Carbon Patents (Class 544/216)
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Patent number: 5420099Abstract: A compound having the formula ##STR1## wherein A is CR.sub.7 ; and R.sup.1 through R.sup.7 are substituents such as hydrogen, halogen, branched and straight chain hydrocarbons, cyclic hydrocarbons, aromatics, and sulfur and nitrogen containing functional groups. Further, R.sup.5 and R.sup.6 may be taken together with the atom to which they are attached to form a group ##STR2## in which R.sup.9 and R.sup.10 are further functional groups. The compounds are useful in herbicidal compositions, particularly in combination with carriers and surfactants. A process for making this compound is also presented.Type: GrantFiled: December 21, 1992Date of Patent: May 30, 1995Assignee: Shell Research LimitedInventor: Trevor W. Newton
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Patent number: 5418212Abstract: The present invention provides a novel alkanoic acid amide derivative of the formula, ##STR1## (wherein R.sup.1 is a hydrogen atom, an alkyl group or an alkoxyalkoxy group, R.sup.2 is a group of --SO.sub.2 R or a hydroxyl group, R.sup.5 is an alkyl group, R.sup.3 is an alkyl group, a cycloalkyl group, a cycloalkenyl group or a phenyl group, R.sup.4 is a hydrogen atom or an alkyl group, X and Y may be the same or different and are an alkoxy group, an alkylamino group or a dialkylamino group, and Z is a methine group or a nitrogen atom) and its salt, a process for preparing the same and a herbicidal composition containing the same as an effective ingredient.This compound kills annual and perennial weeds grown in paddy fields and upland fields at a small dose, and is safe to a useful crop plant.Type: GrantFiled: April 27, 1993Date of Patent: May 23, 1995Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.Inventors: Takumi Yoshimura, Keiji Toriyabe, Katsumi Masuda, Ryo Hanai
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Patent number: 5410048Abstract: A UV absorber of formula (1a) ##STR1## in which E.sub.1, E.sub.2 and E.sub.3 are independently substituted alkyl or substituted silyl or siloxyl moieties, are useful in protecting photographic materials from the deleterious effects of actinic light.Type: GrantFiled: January 21, 1994Date of Patent: April 25, 1995Assignee: Ciba-Geigy CorporationInventors: David G. Leppard, Vien V. Toan, Mario Slongo
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Patent number: 5362874Abstract: A novel light-sensitive bistrihalomethyl-s-triazine compound is provided, which is represented by the general formula (I): ##STR1## wherein T represents a (4,6-bistrihalomethyl-S-triazine-2-yl) group; Y represents a divalent group; and the benzene rings may further contain substituents; a novel photopolymerizable composition containing the same and a light- and heat-sensitive recording material containing the same.Type: GrantFiled: March 13, 1992Date of Patent: November 8, 1994Assignee: Fuji Photo Film Co., Ltd.Inventors: Ken Iwakura, Yuichi Wakata, Hirotaka Matsumoto, Mikio Totsuka
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Patent number: 5352654Abstract: N-Pyridinesulfonyl-N'-pyrimidinyl- and -triazinylureas of the formula I ##STR1## in which R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 C.sub.4 haloalkoxy or CF.sub.3 ; R.sub.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; A is C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl, each of which is monosubstituted to trisubstituted by halogen, or is C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl, each of which is substituted by C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 alkylsulfinyl, C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, amino, C.sub.1 -C.sub.4 alkylamino, C.sub.1 -C.sub.4 dialkylamino or C.sub.2 -C.sub.4 alkynyl, it being possible for the C.sub.2 -C.sub.4 alkenyl radical and the C.sub.5 -C.sub.Type: GrantFiled: May 30, 1990Date of Patent: October 4, 1994Assignee: Ciba-Geigy CorporationInventors: Werner Fory, Rolf Schurter
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Patent number: 5347004Abstract: A mixture of amines made by reacting an amine compound with an aldehyde compound has been found to reduce the levels of H.sub.2 S in liquid or gaseous hydrocarbon streams. At least one of the compounds must have an alkoxyalkylene radical. In one embodiment of the invention, the mixture of amines contains at least one hexahydrotriazine compound of the formula: ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are independently selected from the group consisting of hydrogen and an alkyl radical, including substituted alkyl radicals, of 1 to 5 carbon atoms; where at least one of the groups is an alkoxyalkylene group. In another embodiment of the invention, the amine mixture may contain other by products, such as the monomers which make up the hexahydrotriazine, with or without the hexahydrotriazine being present. These materials are selective to the reduction of H.sub.2 S levels in hydrocarbon or aqueous streams in the presence of CO.sub.2 which does not compromise their performance.Type: GrantFiled: October 9, 1992Date of Patent: September 13, 1994Assignee: Baker Hughes, Inc.Inventors: Gordon T. Rivers, Richard L. Rybacki
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Patent number: 5326762Abstract: Amides of the formula ##STR1## wherein R.sub.1 and R.sub.2 are independently heteroaryl, X-substituted heteroaryl, X-substituted phenyl, N-substituted triazinyl or N-substituted imidazolyl;and in addition, one of R.sub.1 and R.sub.2 can be as defined above and the other can be phenyl;R.sub.3 is an alkyl chain of 2 to 25 carbon atoms, saturated or unsaturated; an alkyl chain as defined substituted by one or more substituents selected from the group consisting of phenyl, X-substituted phenyl, heteroaryl and X-substituted heteroaryl; an alkyl chain as defined interrupted by one or more groups independently selected from the group consisting of --O--, --S--, --SO--, --SO.sub.2 --, --NH--, --N(lower alkyl)--, --C(O)--, phenylene, X-substituted phenylene, heteroarylene and X-substituted heteroarylene; or an interrupted alkyl chain as defined substituted by one or more substituents selected form the group consisting of phenyl, X-substituted phenyl, heteroaryl and X-substituted heteroaryl;R.sub.Type: GrantFiled: May 19, 1992Date of Patent: July 5, 1994Assignee: Schering CorporationInventors: John Clader, Sundeep Dugar, Timothy Kogan, Bradley Tait, Wayne Vaccaro
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Patent number: 5322845Abstract: An acrylic acid compound useful for fungicides is provided. The compound has the following formula (I) ##STR1## wherein X represents a phenyl group which may be substituted, or a methylene group, n represents 0 or 1, Y represents an oxygen atom or a sulfur atom, Z represents a phenyl group, an aralkyl group, an aromatic heterocyclyl group or an aromatic heterocyclylmethylene group and Z may be substituted.Type: GrantFiled: October 1, 1992Date of Patent: June 21, 1994Assignee: Sumitomo Chemical Company, LimitedInventors: Tsuguhiro Katoh, Atsuo Mizuguchi, Hirotaka Takano
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Patent number: 5306718Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the following general Formulas I, II and III are disclosed: ##STR1## Specifically the compounds are azabicyclo [2.2.1] omimes, azabicyclo [2.2.2] oximes, azabicyclo [2.2.1] amines, azabicyclo [2.2.2] amines, azabicyclo [3.2.1] oximes and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 4 to 5 [3 to 7] carbon atoms.Type: GrantFiled: October 16, 1991Date of Patent: April 26, 1994Assignee: Warner-Lambert CompanyInventors: David J. Lauffer, Walter H. Moos, Michael R. Pavia, Haile Tecle, Anthony J. Thomas
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Patent number: 5306728Abstract: Substituted amine derivatives represented by the general formula ##STR1## wherein Q is -C-D-E- F-G-M- or -N-H-I-J-K-L- [C, D, E, F, G, H, I, J, K and L are each O, S, a carbonyl group, -CHR.sup.2 -, -R.sup.b = or -NR.sup.c - (R.sup.a, R.sup.b and R.sup.c are each H or a lower alkyl group), M and N are each an aromatic ring of 5-6 members optionally having a halogen, OH, LN, a lower alkyl group or a lower alkoxy group, provided that L is not O, S, or -NR.sup.c -]; R is a heterocyclic ring of 5-6 members; R.sup.1 is H, a lower alkyl group, a lower haloalkyl group, a lower alkenyl group, a lower alkynyl group or a cycloalkyl group; R.sup.2, R.sup.3, R.sup.4, R.sup.5 R.sup.6 and R.sup.7 are each H, a halogen or a lower alkyl group or two of them denote a single bond; R.sup.8 and R.sup.9 are each F, CF.sub.3 or a lower alkyl group or are a cycloalkane in combination thereof; and R.sup.10 is H, F, CF.sub. 3 an acetoxy group, a lower alkyl group or a lower alkoxy group.Type: GrantFiled: March 4, 1993Date of Patent: April 26, 1994Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yoshimi Tsuchiya, Takashi Nomoto, Masahiro Hayashi, Yoshikazu Iwasawa, Hitoshi Masaki, Mitsuru Ohkubo, Yumiko Sakuma, Yasufumi Nagata, Toshihiko Satoh, Toshio Kamei
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Patent number: 5286881Abstract: A benzodifuranone compounds of the formula, ##STR1## wherein R.sup.1 and R.sup.2 are each independently a naphthyl group or an unsubstituted or substituted phenyl group, which is useful for dyeing or printing hydrophobic fiber materials, is prepared in high purity and high yield by allowing benzofuran compounds of the formula, ##STR2## wherein R.sup.1 is as defined above, to react with acetonitrile compounds of the formula, ##STR3## wherein R.sup.2 is as defined above, and then carrying out an oxidation reaction to give the benzodifuranone compound.Type: GrantFiled: September 30, 1992Date of Patent: February 15, 1994Assignee: Sumitomo Chemical Company LimitedInventors: Junichi Sekihachi, Jun Yamamoto, Yutaka Kayane
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Patent number: 5276033Abstract: Compounds having the formula (I) ##STR1## wherein: R.sup.1 is methyl, ethyl or isopropyl; R.sup.2 is alkyl, aralkyl, cycloalkyl, cycloalkylmethyl, aryl, heterocyclic, or heterocyclic-substituted thio; R.sup.3 is hydrogen, methyl or ethyl; or R.sup.2 together with R.sup.3 is --(CH.sub.2).sub.n --, wherein n is 3,4 or 5; and A is aromatic heterocyclic; and salts thereof, are valuable agricultural and horticultural anthelmintic, acaricidal and insecticidal agents.Type: GrantFiled: December 17, 1992Date of Patent: January 4, 1994Assignee: Sankyo Company, LimitedInventors: Toshiaki Yanai, Soji Sugai, Hideo Takeshiba, Junzo Tobitsuka, Kazuo Sato, Shinji Yokoi, Shinya Niimi, Akio Saito
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Patent number: 5258515Abstract: The invention relates to aqueous solutions of sodium salts of trimercapto-s-triazine whose molar saturation concentration at 0.degree. C. to 40.degree. C. is above the saturation concentration of trimercapto-s-triazine trisodium salt (TMT-Na.sub.3). More than two but less than three hydrogen atoms of the trimercapto-s-triazine are replaced by sodium ions. The solutions preferably contain trimercapto-s-triazine disodium salt (TMT-Na.sub.2) in addition to a little TMT-Na.sub.3. Surprisingly, the water solubility of TMT-Na.sub.2 is greater than that of TMT-Na.sub.3. The solutions represent a suitable supply form for the active substance trimercapto-s-triazine (TMT-H.sub.3) used in the separation of heavy metals The preparation takes place by means of reacting TMT-Na.sub.3 with TMT-H.sub.3 in a molar ratio of 1:greater than 0-less than 0.5, especially 1:0.1 to 1:<0.5 in aqueous solution.Type: GrantFiled: August 25, 1992Date of Patent: November 2, 1993Assignee: Degussa AktiengesellschaftInventors: Klaus Hentschel, Marc Samson, Marcel Vingerhoets, Karl-Ludwig Weber
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Patent number: 5250521Abstract: Novel substituted pyrazolopyrimidines of formula (I) which are useful as angiotensin II antagonists, are disclosed.Type: GrantFiled: November 25, 1991Date of Patent: October 5, 1993Assignee: Merck & Co., Inc.Inventors: Eric E. Allen, William J. Greenlee, Prasun K. Chakravarty, Malcolm MacCoss, Arthur A. Patchett, Thomas F. Walsh
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Patent number: 5225549Abstract: Lubricants for electromagnetic recording media are characterized in that they are amides, imides or amide-imides consisting of perfluoroalkylpolyether derivatives. The derivatives are reacted with perfluoropolyether radicals and cyclic amino compounds, nitrogen-containing heterocyclic amino compounds and phosphonitrile amide compounds. The general formula is represented by (1)(Rf) l--Z . . . (1)with the molecular weight of the Rf group being comprised between 400 and 10,000.Type: GrantFiled: January 15, 1992Date of Patent: July 6, 1993Inventor: Takateru Dekura
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Patent number: 5216158Abstract: Compounds of general formula I are disclosed ##STR1## wherein R.sup.1 denotes an unsubstituted or substituted carbocyclic or heterocyclic aryl radical,R.sup.2 and R.sup.3 are different from each other and either denote a hydrogen atom or a 4,6-bis-trichloromethyl-s-triazin-2-yl group, andn and m independently of each other, denote one of the numbers 0 and 1.The compounds are effective free-radical-forming photoinitiators and photolytically-activatable acid donors for photosensitive compositions.Type: GrantFiled: October 8, 1991Date of Patent: June 1, 1993Assignee: Hoechst AktiengesellschaftInventors: Georg Pawlowski, Fritz Erdmann, Heidrun Lutz
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Patent number: 5212307Abstract: The invention describes light-sensitive bis-trichloromethyl-s-triazines of the general formula I ##STR1## wherein A denotes the ring members required to complete a 5- or 6-membered heterocyclic ring which may be substituted or may carry a substituted or unsubstituted fused benzene ring,R denotes a substituted or unsubstituted alkyl group andX denotes CH or N.The compounds are readily prepared in high yields. They are suitable for use as light-sensitive free-radical and acid donors in light-sensitive compositions.Type: GrantFiled: April 5, 1990Date of Patent: May 18, 1993Assignee: Hoechst AktiengesellschaftInventor: Wojciech A. Wilczak
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Patent number: 5206364Abstract: The invention provides antifungal agents of the formula: ##STR1## and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF.sub.3 ;R.sup.1 is C.sub.1 -C.sub.4 alkyl;R.sup.2 is H or C.sub.1 -C.sub.4 alkyl; and"Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, halo, CF.sub.3, CN, NO.sub.2, NH.sub.2, --NH(C.sub.1 -C.sub.4 alkanoyl) or --NHCO.sub.2 (C.sub.1 -C.sub.4 alkyl).Type: GrantFiled: March 4, 1992Date of Patent: April 27, 1993Assignee: Pfizer Inc.Inventors: Roger P. Dickinson, Kenneth Richardson
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Patent number: 5201937Abstract: Salicylic acid derivatives of the formula I ##STR1## (R.sup.1 is succinimidoxy; unsubstituted or substituted hetaryl; OR.sup.5 where R.sup.5 is substituted or unsubstituted cycloalkyl, alkyl, alkenyl, alkynyl, phenyl or substituted methyleneamino; OR.sup.8 where R.sup.8 is hydrogen, alkali metal or alkaline earth metal cation, ammonium or organic ammonium;R.sup.2 and R.sup.3 are each C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.2 -haloalkyl, C.sub.1 -C.sub.4 -alkoxy or C.sub.1 -C.sub.2 -haloalkoxy and/or C.sub.1 -C.sub.4 -alkylthio;R.sup.4 is ethynyl or unsubstituted or substituted vinyl;X is oxygen or sulfur;Z is nitrogen or methine)are used as herbicides and bioregulators.Type: GrantFiled: October 16, 1991Date of Patent: April 13, 1993Assignee: BASF AktiengesellschaftInventors: Joachim Rheinheimer, Karl Eicken, Uwe J. Vogelbacher, Karl-Otto Westphalen, Matthias Gerber, Helmut Walter
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Patent number: 5186734Abstract: Herbicidal bisazinyl compounds of the formula ##STR1## in which A.sup.1 and A.sup.2 are identical or different and represent nitrogen or a C--X group, X representing hydrogen, halogen, alkyl or alkoxy, andQ.sup.1 and Q.sup.2 are identical or different and represent oxygen, sulphur, NH or N-alkyl,(the substituents R, X.sup.1, X.sup.2, Y.sup.1, Y.sup.2 and Z representing a variety of organic radicals).The compounds of the formulas ##STR2## are also new.Type: GrantFiled: September 11, 1991Date of Patent: February 16, 1993Assignee: Bayer AktiengesellschaftInventors: Roland Andree, Mark W. Drewes, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt
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Patent number: 5187175Abstract: The present invention is novel compounds which are 2-carbonyl substituted-5-hydroxy-1,3-pyrimidines and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever and the like. Thus, the present invention is also a pharmaceutical composition or method of manufacturing a pharmaceutical composition for the use of treating the noted conditions.Type: GrantFiled: March 6, 1992Date of Patent: February 16, 1993Assignee: Warner-Lambert CompanyInventors: Thomas R. Belliotti, David T. Connor, Catherine R. Kostlan, Steven R. Miller
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Patent number: 5186736Abstract: Compounds of the formula I or salts thereof ##STR1## where R.sup.1 is H or an aliphatic radical; R.sup.2 and R.sup.3 are H, alkyl or phenyl; W is O, S, NR.sup.4 or NOR.sup.4 ; X is CHR.sup.2, O or NR.sup.4 ; L is a (substituted) phenyl, naphthyl or monocyclic heteroaryl radical, A is a (substituted) pyrimidyl, triazinyl, triazolyl or bicyclic heteroaryl radical, and m and n are 0 or 1, have advantageously herbicidal or plant growth-regulating properties.Type: GrantFiled: July 11, 1991Date of Patent: February 16, 1993Assignee: Hoechst AktiengesellschaftInventors: Oswald Ort, Lothar Willms, Klaus Bauer, Hermann Bieringer, Arno Schulz
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Patent number: 5185445Abstract: 2-(2-Hydroxyphenyl)-4,6-diaryl-1,3,5-triazines, which carry in the 4-position of the 2-hydroxyphenyl radical a silyl group linked through oxygen to the phenyl nucleus, as well as condensation products whose ##STR1## units contain 2-(2-hydroxyphenyl)-4,6-diaryl-1,3,5-triazines in the side-chain, are UV absorbers which are suitable for use as stabilizers for organic polymers.Type: GrantFiled: February 27, 1992Date of Patent: February 9, 1993Assignee: Ciba-Geigy CorporationInventors: Roger Meuwly, Mario Slongo, Andreas Valet
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Patent number: 5158954Abstract: Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein K is oxygen or sulphur; Z is optionally substituted aryl or optionally substituted heteroaryl; X is O, S(O).sub.n, NR.sup.4, CR.sup.1 R.sup.2, CHR.sup.5, CO, CR.sup.1 (OR.sup.2), C.dbd.CR.sup.1 R.sup.2, CHR.sup.1 CHR.sup.2, CR.sup.1 .dbd.CR.sup.2, CHR.sup.1 CR.sup.2 .dbd.CH, C.dbd.C, OCHR.sup.1, CHR.sup.1 O, OCHR.sup.1 O, S(O).sub.n CHR.sup.1, S(O).sub.n CHR.sup.1 O, CHR.sup.1 S(O).sub.n, CHR.sup.1 OSO.sub.2, NR.sup.4 CHR.sup.1, CHR.sup.1 NR.sup.4, CO.sub.2, O.sub.2 C, SO.sub.2 O, OSO.sub.2, CO.CO, COCHR.sup.1, COCHR.sup.1 O, CHR.sup.1 CO, CHOH.CHR.sup.1, CHR.sup.1.CHOH, ##STR2## CONR.sup.4, OCONR.sup.4, NR.sup.4 CO, CSNR.sup.4, OCS.NR.sup.4, SCO.NR.sup.4, NR.sup.4 CO.sub.2, NR.sup.4 CS, NR.sup.4 CSO, NR.sup.4 COS, NR.sup.4 CONR.sup.4, S(O).sub.n NR.sup.4, NR.sup.4 S(O).sub.n, CS.sub.2, S.sub.2 C, CO.S, SCO, N.dbd.N, N.dbd.CR.sup.1, CR.sup.1 .dbd.N, CHR.sup.1 CHR.sup.2 CH(OH), CHR.sup.1 OCO, CHR.sup.1 SCO, CHR.sup.1 NR.sup.Type: GrantFiled: October 15, 1990Date of Patent: October 27, 1992Assignee: Imperial Chemical Industries PLCInventors: John M. Clough, Christopher R. A. Godfrey, Stephen P. Heaney, Kenneth Anderton
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Patent number: 5153323Abstract: Radiation-sensitive organo-halogen compounds having a photo-labile halomethyl-1,2,5-triazine moiety and at least one photoinitator moiety within one molecule. The compounds of this invention are good photoinitiators, and compositions containing them can be used in printing, duplicating, copying, and other imaging systems. The compounds of this invention eliminate the need for a combination of photoinitiators in a photocurable or photopolymerizable composition.Type: GrantFiled: March 28, 1991Date of Patent: October 6, 1992Assignee: Minnesota Mining and Manufacturing CompanyInventors: Mitchell A. Rossman, James A. Bonham
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Patent number: 5149357Abstract: Compound of the formula ##STR1## in which A is O, S, or NR.sup.3 ; G is CH or N; R and R.sup.1 are independently alkyl, alkoxy, haloalkoxy or alkylamino; R.sup.2 is phenyl, substituted phenyl, alkyl, cycloalkyl, haloalkyl or --CH.sub.2 [(R.sup.4)C(R.sup.5).sub.n --Z; R.sup.3 and R.sup.7 are, independently, hydrogen, alkyl, --C(O)NH.sub.2 or --C(O)alkyl; R.sup.4 and R.sup.5 are independently hydrogen, alkyl, or halogen; R.sup.6 is halogen, alkyl, alkoxy, haloalkoxy, NO.sub.2, amino, alkyl substituted amino, or acyl substituted amino; n is 0 to 5; Z is cyano, amino, alkylamino, dialkylamino, --NHCO.sub.2 alkyl, alkoxy, alkylthio, alkylsulfonyl, alkenyl, alkynyl, phenyl or substituted phenyl; and Q is hydrogen, halogen, alkyl, alkoxy, haloalkoxy, nitro, amino, haloalkyl, alkythio, alkylsulfonyl, phenyl, substituted phenyl or phenoxy; or a 5 or 6 membered aromatic heterocycle having the formula ##STR2## in which "m" is 0 or 1; A' is O, S, or NR.sup.Type: GrantFiled: June 19, 1990Date of Patent: September 22, 1992Assignee: FMC CorporationInventors: John A. Dixson, Natesan Murugesan, Keith D. Barnes
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Patent number: 5138064Abstract: Novel 3-pyrrolidinylthio-1-azabiycyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and pharmaceutically acceptable salts thereof have antimicrobial activity and are useful as medicaments in the treatment of infectious diseases caused by pathogenic microorganisms.Type: GrantFiled: February 6, 1990Date of Patent: August 11, 1992Assignee: Fujisawa Pharmaceutical Company, Ltd.Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
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Patent number: 5120843Abstract: The aromatic amines (I), alkyl amines (II), bicyclic amines (III). ##STR1## cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pharmaceutical agents for treating a number of conditions including spinal trauma, mild and/or moderate to severe head injury, etc. Also disclosed is a method of treatment using the 3,4-dihydrobenzopyrans (XI).Type: GrantFiled: October 23, 1989Date of Patent: June 9, 1992Assignee: UpjohnInventors: John M. McCall, Donald E. Ayer, E. Jon Jacobsen, Frederick J. VanDoornik, John R. Palmer
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Patent number: 5116977Abstract: Radiation-sensitive organo-halogen compounds having a photo-labile halomethyl-1,3,5-triazine moiety and at least one amine-containing moiety within one molecule. The compounds serve the dual purpose of photoinitiation and polymerization acceleration, thereby eliminating the need for the use of two separate compounds. The compounds of this invention are good photoinitiators, and compositions containing them are useful in printing, duplicating, copying, and other imaging systems.Type: GrantFiled: January 14, 1991Date of Patent: May 26, 1992Assignee: Minnesota Mining and Manufacturing CompanyInventors: Mitchel A. Rossman, James A. Bonham
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Patent number: 5098465Abstract: The invention relates to new 2-pyrimidinyl- and 2-triazinylacetic acid derivatives of general formula I ##STR1## in which A, R.sup.2-5 and X have the meanings given in the description, processes for their preparation and their use as herbicides, fungicides and plant growth regulants.Type: GrantFiled: October 1, 1990Date of Patent: March 24, 1992Assignee: Shering AktiengesellschaftInventors: Gabriele Kruger, Christoph Harde, Nikolaus Heinrich, Anita Kruger, Erhard Nordhoff, Gerhard Tarara, Peter Wegner, Clemens Kotter, Gerhard Johann, Richard Rees, Graham P. Jones
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Patent number: 5095021Abstract: Phenylalkylamines of the formula ##STR1## where n is 5, 6, 7, 8 or 9, m is 1, 2 or 3, R.sup.1 is methyl, halogen, substituted or unsubstituted aryl or substituted or unsubstituted phenoxy, and, when m is 2, two adjacent radicals R.sup.1 together denote the radical ##STR2## X is oxygen, except when R.sup.1 is methyl, or the radical ##STR3## R.sup.4 is isopropyl, tert-butyl or substituted or unsubstituted phenyl and R.sup.5 is H or OH, R.sup.2 and R.sup.3 are each hydrogen and, when X is oxygen, R.sup.2 and R.sup.3 additionally denote methyl or ethyl, and their plant-tolerated salts, and fungicides containing these compounds.Type: GrantFiled: April 29, 1991Date of Patent: March 10, 1992Assignee: BASF AktiengesellschaftInventors: Matthias Zipplies, Ernst Buschmann, Eberhard Ammermann, Gisela Lorenz
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Patent number: 5089044Abstract: The invention relates to new substituted pyrimidinyloxy(thio)- and triazinyloxy(thio)acrylic acid derivative of general formula I ##STR1## in which A, G, R.sup.1-3, X and Y have the meanings given in the description, processes for their preparation and their use as herbicides, fungicides and plant growth regulants.Type: GrantFiled: July 19, 1990Date of Patent: February 18, 1992Assignee: Schering AktiengesellschaftInventors: Christoph Harde, Erhard Nordhoff, Anita Kruger, Gabriele Kruger, Gerhard Tarara, Peter Wegner, Nikolaus Heinrich, Clemens Kotter, Gerhard Johann, Richard Rees
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Patent number: 5084570Abstract: There is disclosed a process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines of formula (1) as indicated in claim 1, which process comprises reacting, in a first step, a compound of formula (4) as indicated in claim 1, with the aid of a Lewis acid, in the presence of xylene or toluene, with a substituted benzene of formula (5) as indicated in claim 1, and, in a second step, reacting the resultant compound of formula (2) as indicated in claim 1, in the presence of toluene or xylene, with chlorine or sulfuryl chloride, to give the compound of formula (3) as indicated in claim 1, and, in a third step, reacting the resultant compound with 1,3-dihydroxybenzene, with the aid of a Lewis acid, to give the compound of formula (1), in the presence of toluene, xylene or a mixture of xylene isomers.Type: GrantFiled: April 18, 1990Date of Patent: January 28, 1992Assignee: Ciba-Geigy CorporationInventors: Kurt Burdeska, Franz Gunter
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Patent number: 5084459Abstract: There is provided a pest control composition containing a compound represented by the formula, ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same or different and independently mean a hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted and X means an electron attracting group or a salt thereof.The compounds are of minimal toxicity to man, domestic animals and fish and selectively display remarkable control effect on pests.Type: GrantFiled: October 25, 1989Date of Patent: January 28, 1992Assignee: Takeda Chemical Industries, Ltd.Inventors: Hideki Uneme, Isao Minamida, Tetsuo Okauchi, Noriko Higuchi
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Patent number: 5079361Abstract: Cross-linking reagents which are highly specific for sulphydryl groups and react with thiols at an excellent rate. The essential feature of the reagents is at least one vinyl group conjugated with an armoatic nitrogen heterocycle. Particular examples include vinyl pyridines, vinyl pyrimidines and vinyl triazines.Type: GrantFiled: September 9, 1988Date of Patent: January 7, 1992Assignee: Celltech LimitedInventors: Rikki P. Alexander, Michael A. W. Eaton, Thomas A. Millican, Richard C. D. Titmas
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Patent number: 5075316Abstract: Novel compounds of the formula ##STR1## in which: R.sub.1 and R.sub.2 independently of one another are hydrogen, halogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.2 halogenoalkyl, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 halogenoalkoxy; R.sub.3 is C.sub.3 -C.sub.6 cycloalkyl or C.sub.3 -C.sub.6 cycloalkyl which is substituted by up to three identical or different methyl or halogen groups; R.sub.4 is halogen, thiocyano, --OR.sub.5, --SR.sub.5 or --NR.sub.5 R.sub.6, in which R.sub.5 and R.sub.6 are halogen groups; R.sub.4 is halogen, thiocyano, --OR.sub.5, --SR.sub.5 or --NR.sub.5 R.sub.6, in which R.sub.5 and R.sub.6 are as defined herein, are novel active compounds for preventing attack of plants by microorganisms. The compounds can be employed as microbicides as such or in the form of suitable agents.Type: GrantFiled: March 20, 1990Date of Patent: December 24, 1991Assignee: Ciba-Geigy CorporationInventor: Adolf Hubele
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Patent number: 5064959Abstract: Compounds of general formula ##STR1## are disclosed in which R.sup.1 and R.sup.2 are different from one another and denote either a hydrogen atom or a radical of the formula ##STR2## R.sup.3 denotes a substituted or unsubstituted alkoxy, alkenyloxy, alkynyloxy or aryloxy radical, a hydroxyl group or a halogen atom andn the number 0 or 1.The compounds are useful intermediates for the preparation of photoinitiators and are themselves active as photoinitiators.Type: GrantFiled: March 1, 1989Date of Patent: November 12, 1991Assignee: Hoechst AktiengesellschaftInventors: Georg Pawlowski, Fritz Erdmann, Heidrun Lutz
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Patent number: 5061812Abstract: This invention relates to a novel ascorbic acid derivative having excellent antioxidant action and a process for preparing the same.Furthermore, this invention also relates to a novel antioxidant comprising the aforementioned ascorbic acid derivative or other known ascorbic acid derivatives.Type: GrantFiled: July 20, 1989Date of Patent: October 29, 1991Assignee: Nippon Hypox Laboratories IncorporatedInventors: Toshio Satoh, Yasunori Niiro, Hisao Kakegawa, Hitoshi Matsumoto
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Patent number: 5057143Abstract: Salicyclic acid derivatives and their sulfur analogs of the formula I ##STR1## where R.sup.1 to R.sup.5, X, Y and Z have the meanings given in the disclosure and claims, agents containing the salicyclic acid derivatives, and their use as herbicides.Type: GrantFiled: June 14, 1989Date of Patent: October 15, 1991Assignee: BASF AktiengesellschaftInventors: Joachim Rheinheimer, Karl Eicken, Peter Plath, Gerhard Paul, Albrecht Harreus, Karl-Otto Westphalen, Bruno Wuerzer, Klaus Grossmann, Wilhelm Rademacher, Johann Jung
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Patent number: 5055579Abstract: Compounds of general formula I are disclosed ##STR1## wherein L denotes a hydrogen atom, an aryl radial or a substituent of the formula ##STR2## M denotes an alkylene radical or alkenylene radical or a 1,2-arylene radical,Q denotes a sulfur, selenium or oxygen atom, a dialkylmethylene group, an alken 1,2-ylene radical, a 1,2-phenylene radical or an N-R.sup.1 group,denotes an alkyl, aralkyl, aryloxyalkyl or alkoxyalkyl radical,R.sup.2 and R.sup.3 denote a hydrogen atom or a 4,6-bis-trichloromethyl-s-triazin-2-yl group, andn is 0 or 1.The compounds are suitable for use as photoinitiators in photosensitive systems that are induced to reaction by free radicals or acid cations. The compounds are characterized by high sensitivity in the visible spectral region.Type: GrantFiled: March 1, 1989Date of Patent: October 8, 1991Assignee: Hoechst AktiengesellschaftInventors: Georg Pawlowski, Heidrun Lutz
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Patent number: 5053411Abstract: This invention pertains to novel substituted N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides useful as analgesics, and methods of administering analgesia, which comprises the systemic administration to mammals of such compounds, and pharmaceutical compositions containing such compounds, wherein the novel compounds have the general formula: ##STR1## including optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the disclosure.Type: GrantFiled: April 20, 1989Date of Patent: October 1, 1991Assignee: Anaquest, Inc.Inventors: Jerome R. Bagley, Nhora L. Lalinde, Bao-Shan Huang, H. Kenneth Spencer
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Patent number: 5043443Abstract: Novel aminomethyloxooxazolidinyl arylbenzene derivatives, wherein the aryl includes the phenyl, substituted phenyl, pyridyl, and substituted pyridyl groups, such as (l)-N-{3-[4- (4'-pyridyl)phenyl]-2-oxooxazolidin-5-ylmethyl}acetamide, possess useful antibacterial activity.Type: GrantFiled: July 24, 1990Date of Patent: August 27, 1991Assignee: Du Pont Merck Pharmaceutical CompanyInventors: Randall K. Carlson, Chung-Ho Park, Walter A. Gregory
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Patent number: 5041545Abstract: Hydrazide functionalized 2-hydroxybenzophenone ultraviolet light and heat stabilizers and derivatives are disclosed having the general formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X, Y, Z, all substituents thereof, and n are set forth in the Summary of the Invention. Y--N(R.sup.6)--Z is the hydrazide or derivative group and --X--R.sup.5 -- links the hydrazide group to an aromatic nucleus of the optionally substituted benzophenone group. Derivatives are, for example, acyl hydrazides, diacyl hydrazides (including imides), hydrazones and alkyl hydrazides. The compounds are useful as ultraviolet light absorbers and heat stabilizers for plastics.Type: GrantFiled: April 6, 1989Date of Patent: August 20, 1991Assignee: Atochem North America, Inc.Inventor: Terry N. Myers
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Patent number: 5037979Abstract: Novel cationic compounds of formula ##STR1## wherein R.sub.1 and B are as defined in claim 1, are used for photochemically stabilizing basic dyeable polyamide, polyacrylonitrile and polyester fibre materials. The preparation of the novel compounds and of the novel starting materials is also described.Type: GrantFiled: July 18, 1989Date of Patent: August 6, 1991Assignee: Ciba-Geigy CorporationInventors: Alfred Hohener, Kurt Burdeska, Gerhard Reinert
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Patent number: 5026418Abstract: Pyrimidine compounds useful as plant growth regulators have the formula (I): ##STR1## wherein Y is an optionally substituted secondary or tertiary alkyl group containing from 3 to 7 carbon atoms or an optionally substituted cycloalkyl or alkylcycloalkyl group containing from 3 to 7 carbon atoms; R.sup.1 and R.sup.2, which may be the same or different, are hydrogen or a lower alkyl group; A is an optionally substituted heterocyclic group, for example thienyl or pyridyl; n is an integer which may be from 0 to 2 and is preferably 0; and R.sup.3 is hydrogen, an alkyl group containing from 1 to 4 carbon atoms, or an alkenyl or alkynyl group containing from 2 to 4 carbon atoms.Type: GrantFiled: February 20, 1990Date of Patent: June 25, 1991Assignee: Imperial Chemical Industries PLCInventor: Kevin R. Lawson
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Patent number: 5021486Abstract: Bis(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidin-4-yl) malonate or malonamide derivatives of 1,3,5-triazine corresponding to the formula ##STR1## are effective light stabilizers in a wide variety of substrate systems.Type: GrantFiled: February 14, 1989Date of Patent: June 4, 1991Assignee: Ciba-Geigy CorporationInventor: James P. Galbo
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Patent number: 5019611Abstract: There is disclosed compounds having, within their structural formulae, a trivalent moiety: ##STR1## which exhibit antiozonant activity when added to rubber compositions at antiozonant effective levels and which exhibit synergistic antiozonant activity when used with conventional antiozonants in rubber compositions. There is also disclosed novel compounds which can be used as antiozonants.Type: GrantFiled: January 15, 1987Date of Patent: May 28, 1991Assignee: The Goodyear Tire & Rubber CompanyInventors: Kevin L. Rollick, James G. Gillick, Joseph A. Kuczkowski
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Patent number: 5011860Abstract: Aryl-substituted naphthyridines and pyridopyrazines are disclosed which are useful in treating allergic reactions, inflammation, peptic ulcers and/or hyperproliferative skin disease. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed.Type: GrantFiled: June 26, 1989Date of Patent: April 30, 1991Assignee: Schering CorporationInventors: David J. Blythin, Ho-Jane Shue
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Patent number: 5002694Abstract: Nitrogen-containing heterocyclic compounds of the formula II ##STR1## wherein R.sup.1 and R.sup.2 in each case denote an alkyl group having 1 to 15 C atoms, wherein one or more CH.sub.2 groups may also be replaced by a grouping selected from the group comprising --O--, --S--, --CO--, --O--CO--, --O--COO--, --CO--O--, --CH.dbd.CH--, --CH--halogen and --CHCN--, or else by a combination of two suitable groupings, two heteroatoms not being directly linked to each other,m denotes 0 or 1,Ar denotes 1,4-phenylene, 4,4'-biphenylyl or 2,6-naphthylene, wherein one or more CH groups are in each case replaced by N,Z denotes --C--O--, --O--CO--, --CH.sub.2 O--, --OCH.sub.2 --, --CH.sub.2 CH.sub.2 --, --CH.sub.2 CHCN--, --CHCNCH.sub.2 --, --CH.dbd.CH or a single bond, andA denotes unsubstituted 1,4-cyclonexylene or 11,4-cyclohexylene substituted in position 1 or position 4 by CN,with the proviso that if A=unsubstituted 1,4-cyclonexylene, Z denotes --CHCNCH.sub.2 -- or --CH.sub.2 CHCN-- and/or at least one CH.sub.Type: GrantFiled: May 13, 1987Date of Patent: March 26, 1991Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Andreas Wachtler, Rudolf Eidenschink, Joachim Krause, Bernhard Scheuble
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Patent number: RE34201Abstract: This invention pertains to novel substituted N/aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides useful as analgesics, and methods of administering analgesia, which comprises the systemic administration to mammals of such compounds, and pharmaceutical compositions containing such compounds, wherein the novel compounds have the general formula: ##STR1## including optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the disclosure.Type: GrantFiled: April 14, 1992Date of Patent: March 23, 1993Assignee: Anaquest, Inc.Inventors: Jerome R. Bagley, Nhora L. Lalinde, Bao-Shan Huang, H. Kenneth Spencer