Patent number: 6642273
Abstract: An unsaturated derivative at the 4-position of 6-tert-butyl-1,1-dimethylindane corresponding to the following formula:
in which:
X represents:
a divalent radical of formula:
and Y represents a divalent radical of following formula:
R1 represents —CH3, —(CH2)p—OR4, —(CH2)p—COR5 or —S(O)t—R6,
p being 0, 1, 2 or 3,
t being 0, 1 or 2,
R4 represents H, lower alkyl, —COR7, aryl, aralkyl, mono- or polyhydroxyalkyl, or a polyether radical,
R5 represents H, lower alkyl, —OR8 or
R6 represents H or lower alkyl,
R7 represents lower alkyl,
R8 represents H, alkyl, alkenyl, alkynyl, aryl, aralkyl, mono- or polyhydroxyalkyl, a sugar residue selected from the group consisting of residues deriving from glucose, galactose, mannose and glucuronic acid or an amino acid residue deriving from lysine, glycine and aspartic acid,
r′ and r″, which are identical or different, represent H, low
Type:
Grant
Filed:
August 9, 2002
Date of Patent:
November 4, 2003
Assignee:
Galderma Research & Development
Inventors:
Angel De Lera, Beatriz Dominguez