Ring Carbon Is Shared By Each Of The Three Cyclos (e.g., 1,8 Naphthalimides, Etc.) Patents (Class 546/98)
  • Patent number: 10113031
    Abstract: The present invention relates to a composition containing a particulate solid, an organic or aqueous medium and a dispersant that may be a reaction product of an organic di or polyepoxide with a primary amine, aminoalcohol, amino acid, hydroxyacid or alcohol containing a fused or non-fused aromatic imide group. The invention further provides compositions for coatings, inks, toners, plastic materials (such as thermoplastics), plasticizers, plastisols, crude grinding and flush.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: October 30, 2018
    Inventors: Dean Thetford, Andrew J. Shooter, Robert A. Jennings
  • Patent number: 9505721
    Abstract: [Problem] to provide an aromatic imide compound wherein the sensitivity for visible light such as g-line, h-line etc. is increased and solubility is also improved. [Means for solving problem] The aromatic imide compound of the invention is a compound represented by the formula (1) below (in the formula, R1 represents a haloalkyl group having 1 to 7 carbon atoms or a haloaryl group, R2 represents a group containing a substituted or unsubstituted, aliphatic or aromatic group which may have a heteroatom, and adjacent R2s may form an imido group by connecting each other, R3 represent a halogen atom or a hydrocarbon group, m is zero or an integer of 1 or more, n is zero or an integer of 1 or more, and a sum of n and m is 1 to 6). These compounds are obtained by following processes. A halogenated naphtharic anhydride is reacted with an aromatic group-containing hydrocarbon such as ethynylbenzene to prepare a naphthalic anhydride substituted by an aromatic group-containing group.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: November 29, 2016
    Assignee: AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L.
    Inventors: Eri Hirahara, Ralph Dammel, Georg Pawlowski
  • Patent number: 9475774
    Abstract: Novel alpha-hydrogen substituted nitroxyl compounds and their corresponding oxidized (oxoammonium cations) and reduced (hydroxylamine) forms, and the use of such compounds, inter alia, for oxidation of primary and secondary alcohols to aldehydes and ketones, respectively; resolution of racemic alcohols; desymmetrization of meso-alcohol; as radicals and spin trapping reagents; and as polymerization agents. Processes for preparing the novel nitroxyl/oxoammonium/hydroxylamine compounds from the corresponding amines, and certain novel amine derivatives and their uses. The compounds and amine precursors are useful as ligands for transition metals and as organocatalysts in e.g., aldol reactions.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: October 25, 2016
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Alex M. Szpilman, Michal Amar
  • Patent number: 8945703
    Abstract: The invention relates to a polyester film incorporating at least one UV stabilizer of the formula I, in which R1 is hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl, or heteroaryl, and R2 is a moiety which contains at least one ?-electron system, which contains a carbon atom and at least one further atom selected from carbon, oxygen, and nitrogen, where the moiety R2 contains at least one atom different from carbon, where the film includes at least one further UV absorber which does not correspond to the formula I. The invention further relates to a process for producing the film, and also to articles formed from the film.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: February 3, 2015
    Assignee: Mitsubishi Polyester Film GmbH
    Inventors: Holger Kliesch, Oliver Klein, Andreas Bork, Ingo Fischer
  • Publication number: 20140350258
    Abstract: Novel alpha-hydrogen substituted nitroxyl compounds and their corresponding oxidized (oxoammonium cations) and reduced (hydroxylamine) forms, and the use of such compounds, inter alia, for oxidation of primary and secondary alcohols to aldehydes and ketones, respectively; resolution of racemic alcohols; desymmetrization of meso-alcohol; as radicals and spin trapping reagents; and as polymerization agents. Processes for preparing the novel nitroxyl/oxoammonium/hydroxylamine compounds from the corresponding amines, and certain novel amine derivatives and their uses. The compounds and amine precursors are useful as ligands for transition metals and as organocatalysts in e.g., aldol reactions.
    Type: Application
    Filed: August 6, 2014
    Publication date: November 27, 2014
    Inventors: Alex M. Szpilman, Michal Amar
  • Publication number: 20140094609
    Abstract: The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 3, 2014
    Inventors: Brandon H. Brown, Xiang Wang, Keith R. Fandrick, Joe Ju Gao, Nizar Haddad, Serge R. Landry, Wenjie Li, Zhi-Hui Lu, Bo Qu, Diana C. Reeves, Carl Thibeault, Yongda Zhang
  • Patent number: 8680268
    Abstract: Disclosed are a novel sulfonic acid derivative compound and a novel naphthalic acid derivative compound with high solubility in organic solvents, good photosensitivity, and suitability as a photoacid generator and a polymerization initiator. The sulfonic acid derivative compound is represented by the formula (I) (wherein R01, R04, R05, and R06 represent a hydrogen atom; any one of R02 and R03 represents an alkoxy group having a carbon number of 4 to 18 which may be substituted with an alicyclic hydrocarbon group, a heterocyclic group, or a halogen atom and which may have a branch, or the like; and R07 represents an aliphatic hydrocarbon group having a carbon number of 1 to 18 which may be substituted with a halogen atom and/or an alkylthio group, or the like).
    Type: Grant
    Filed: January 12, 2011
    Date of Patent: March 25, 2014
    Assignee: Adeka Corporation
    Inventors: Toshihiko Murai, Yoshie Makabe, Shohei Fujita
  • Patent number: 8614225
    Abstract: The present application relates to a process for purification of palonosetron or its salt substantially free of its R-isomer and structure related impurities.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: December 24, 2013
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Raghavendracharyulu Venkata Palle, Madhavrao Marathe Anant, Nageshwar Gunda
  • Patent number: 8507590
    Abstract: A compound of Formula (I) wherein R1, R2, and R3 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality, with the proviso that R2 and R3 are not hydrogen when R1 is a methyl or hydrogen; R4 and R5 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R7 and R8 are independently at each occurrence, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R6 is a C2-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality; and “n” and “m” are each independently integers having a value of 0 to 3.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: August 13, 2013
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventors: Shantaram Narayan Naik, Adil Minoo Dhalla, Yogendrasinh Bharatsinh Chauhan
  • Patent number: 8362276
    Abstract: The present invention provides a novel ?-sulfonimide compound having at least one imide group and at least one sulfonyl group and a method for preparing the same.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: January 29, 2013
    Assignee: INKTEC Co., Ltd.
    Inventors: Kwang-Choon Chung, Hyun-Nam Cho, Myoung-Seon Gong, Yun-Ho Jung
  • Patent number: 8350036
    Abstract: The present invention relates to chemical compounds with anti-cancer and anti-parasite activity. The invention relates, above all, to novel bisnaphthalimidopropyl derivatives with specific cytotoxic activity towards human cancer cells and protozoan cells capable of causing parasitic diseases in humans. The invention further relates to chemical compounds to be administered especially to humans and in particular for therapeutic use.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: January 8, 2013
    Assignee: Universidade Do Porto
    Inventors: Anabela Cordeiro Da Silva, Joana Alexandra Pinto Da Costa Tavares, Paul Kong Thoo Lin
  • Patent number: 8329377
    Abstract: An imide compound represented by the formula (I): wherein R1 represents a C1-C20 aliphatic hydrocarbon group etc., W1 represents —CO—O— etc., Q1 and Q2 each independently represent a fluorine atom etc., and A represents a group represented by the formula (I-1): wherein A1 represents —CH2—CH2— etc., and a chemically amplified resist composition containing the same.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: December 11, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Ichiki Takemoto, Tatsuro Masuyama, Takashi Hiraoka
  • Publication number: 20120309759
    Abstract: The present invention embraces methods for identifying compounds that modulate the activity of telomerase. Compounds of the invention are identified by designing or screening for a compound which binds to at least one amino acid residue of the TRBD, “thumb,” “finger,” and/or “palm” domain; or FP-pocket, PT-pocket or Th-pocket of telomerase and testing the compound for its ability to modulate the activity of telomerase. Compounds selected for interacting with the T-pocket or Fingers-Palm pocket of telomerase are also provided.
    Type: Application
    Filed: February 8, 2011
    Publication date: December 6, 2012
    Applicant: The Wistar Institute
    Inventor: Emmanuel Skordalakes
  • Publication number: 20120289697
    Abstract: Disclosed are a novel sulfonic acid derivative compound and a novel naphthalic acid derivative compound with high solubility in organic solvents, good photosensitivity, and suitability as a photoacid generator and a polymerization initiator. The sulfonic acid derivative compound is represented by the formula (I) (wherein R01, R04, R05, and R06 represent a hydrogen atom; any one of R02 and R03 represents an alkoxy group having a carbon number of 4 to 18 which may be substituted with an alicyclic hydrocarbon group, a heterocyclic group, or a halogen atom and which may have a branch, or the like; and R07 represents an aliphatic hydrocarbon group having a carbon number of 1 to 18 which may be substituted with a halogen atom and/or an alkylthio group, or the like).
    Type: Application
    Filed: January 12, 2011
    Publication date: November 15, 2012
    Inventors: Toshihiko Murai, Yoshie Makabe, Shohei Fujita
  • Publication number: 20120203001
    Abstract: A compound of Formula (I) wherein R1, R2, and R3 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality, with the proviso that R2 and R3 are not hydrogen when R1 is a methyl or hydrogen; R4 and R5 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R7 and R8 are independently at each occurrence, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R6 is a C2-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality; and “n” and “m” are each independently integers having a value of 0 to 3.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 9, 2012
    Applicant: SABIC INNOVATIVE PLASTICS IP B.V.
    Inventors: Shantaram Narayan Naik, Adil Minoo Dhalla, Yogendrasinh Bharatsinh Chauhan
  • Patent number: 8211613
    Abstract: The present invention provides a radical generator having a naphthalimide structure or a crosslinking agent and a photosensitive compound having a function as a radical generator. A photoradical polymerization initiator of the present invention comprises a compound (a) having only one naphthalimide structure-containing group in one molecule. The radial generator of the present invention comprises a compound (c) having two or more naphthalimide structure-containing groups in one molecule and also functions as a crosslinking agent. A first photosensitive compound of the present invention comprises a compound (d) having a naphthalimide structure-containing group and an ethylenic unsaturated group in one molecule. A second photosensitive compound of the present invention comprises a polymer (e) of one or more radical polymerizable compounds containing the compound (d).
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: July 3, 2012
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventor: Katsuya Sakayori
  • Patent number: 8188112
    Abstract: The invention relates to compounds for use in medicine.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: May 29, 2012
    Assignee: Agency for Science, Technology and Research
    Inventors: Surana Uttam, Vaidehi Krishnan, Anthony Ting, Hong Hwa Lim
  • Patent number: 8124311
    Abstract: Disclosed are a photosensitive compound containing oxime group which is directly decomposed by exposure to light, which is a molecular resist whose size is smaller than conventional polymer for photoresist, and a photoresist composition including the same. The photosensitive molecular compound has a structure represented by a following formula. In Formula, R1 is hydrogen atom or methyl group (CH3); Ra and Rb each is independently alkyl group of 1-6 carbon atoms, alkylcarbonyl group of 2-7 carbon atoms, aryl group of 6-10 carbon atoms or arylcarbonyl group of 7-11 carbon atoms, and Ra and Rb form one group as an united body, alkyl or cycloalkyl group of 1-20 carbon atoms or arylalkyl group of 7-20 carbon atoms which are doubly bonded to nitrogen atom.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: February 28, 2012
    Assignee: Dongjin Semichem Co., Ltd.
    Inventors: Jung-Youl Lee, Jeong-Sik Kim, Eu-Jean Jang, Jae-Woo Lee, Jae-Hyun Kim
  • Publication number: 20110269791
    Abstract: The present invention relates to compounds defined by Formula (I), wherein the groups A, B, X, m, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11?-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 3, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Stefan Peters, Matthias Eckhardt, Bradford S. Hamilton, Frank Himmelsbach, Joerg Kley, Thorsten Lehmann-Lintz
  • Patent number: 7988741
    Abstract: The present application relates to a novel family of cationic naphthalimide compounds that can be used as a direct dye, and to a dye composition for the dyeing of keratin fibers, in particular human keratin fibers such as the hair, comprising, in a suitable dyeing medium, at least one such compound. The present application also relates to the dyeing process using this composition and its uses.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: August 2, 2011
    Assignee: L'Oreal S.A.
    Inventors: Tiina Luukas, Andrew Greaves, Hervé David
  • Patent number: 7947839
    Abstract: Bis 1,8 naphthalimide compounds including antibody drug conjugate (ADC) are described. Pharmaceutical compositions comprising an effective amount of a 1,8 bis-naphthalimide compound for treatment of hyperproliferative disorders and other disorders are described. Methods are described for killing or inhibiting the proliferation of tumor cells or cancer cells including administering to a patient an effective amount of a 1,8 bis-naphthalimide compound.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: May 24, 2011
    Assignee: Genentech, Inc.
    Inventors: Lewis J. Gazzard, Edward HyungSuk Ha, David Y. Jackson, Joann M. Um
  • Publication number: 20110079773
    Abstract: Disclosed are new selectively functionalized rylene imides and diimides that can exhibit desirable electronic properties and can possess processing advantages including solution-processability and/or good stability at ambient conditions.
    Type: Application
    Filed: August 20, 2010
    Publication date: April 7, 2011
    Inventors: Michael R. Wasielewski, Joseph E. Bullock, Michael T. Vagnini
  • Publication number: 20110065843
    Abstract: A compound of Formula (I) wherein R1, R2, and R3 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality, with the proviso that R2 and R3 are not hydrogen when R1 is a methyl or hydrogen; R4 and R5 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R7 and R8 are independently at each occurrence, a halogen, a cyano functionality, a C1-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C10 aromatic functionality; R6 is a C2-C20 aliphatic functionality, a C3-C10 cycloaliphatic functionality or a C3-C20 aromatic functionality; and “n” and “m” are each independently integers having a value of 0 to 3.
    Type: Application
    Filed: September 17, 2009
    Publication date: March 17, 2011
    Inventors: Shantaram Narayan Naik, Adil Minoo Dhalla, Yogendrasinh Bharatsinh Chauhan
  • Publication number: 20110013124
    Abstract: Lyotropic chromophoric compounds comprised of a naphthalimide derivative, a perylene-3,4-dicarboxylic imide derivative, or a perylenetetracarboxylic diimide derivative are described. The compounds can be used to form liquid crystal systems possessing high quality optical properties. The resulting liquid crystal systems are readily applied onto a substrate to obtain optically isotropic or anisotropic, at least partially crystalline films applicable in various fields.
    Type: Application
    Filed: March 5, 2009
    Publication date: January 20, 2011
    Applicant: Nitto Denko Corporation
    Inventors: Shuangxi Wang, Zongcheng Jiang, Michiharu Yamamoto
  • Patent number: 7868173
    Abstract: The instant invention relates to novel prodrugs of optically pure benzoquinolizine-2-carboxylic acid and pharmaceutical compositions that include the prodrugs. In particular, the present invention relates to the sulfonic acid salts of L-alanine and L-valine prodrugs of S-(?)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid. The compounds and compositions of the invention can be used to treat bacterial Gram-positive, Gram-negative and anaerobic infections, especially infections caused by resistant Gram-positive organism and Gram-negative organism, mycobacterial infections and emerging nosocomial pathogen infections.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: January 11, 2011
    Assignee: Wockhardt Limited
    Inventors: Mahesh Vithalbhai Patel, Vijaya Narayan Desai, Prasad Keshav Deshpande, Ravindra Dattatraya Yeole, Rajesh Prabhakar Kale
  • Publication number: 20100314556
    Abstract: The invention relates to the use of 1,8-naphthalimide derivatives and of their salts as scintillation agents and more specifically as agents for discriminating between fast neutrons and gamma rays. It also relates to liquid scintillators comprising these scintillation agents in solution in a solvent and to novel 1,8-naphthalimide derivates of use as scintillation agents, in particular for discriminating between fast neutrons and gamma rays. Applications: all the fields of use of scintillators and in particular industry, geophysics, fundamental physics, in particular nuclear physics, the safety of goods and people, protection from radiation of workers in the industrial, nuclear and medical sectors, medical imaging, and the like.
    Type: Application
    Filed: January 27, 2009
    Publication date: December 16, 2010
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Matthieu Hamel, Stéphane Normand, Vesna Simic
  • Patent number: 7807836
    Abstract: A process for preparing perylene-3,4:9,10-tetracarboxylic dianhydride, comprising: dimerizing a naphthalene-1,8-dicarboximide of the formula IIa; reoxidizing the resulting alkali metal salt of the leuco form of the perylene-3,4:9,10-tetracarboxylic diimide of the formula Ia; hydrolyzing the diimide to the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid in the presence of an inert organic solvent, of an alkali metal base and of water; and subjecting the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid to the action of an aqueous inorganic acid to convert it into perylene-3,4:9,10-tetracarboxylic dianhydride; wherein R3 is cyclohexyl or phenyl which may each be substituted by up to three C1-C4-alkyl radicals, and the dimerizing is in a substantially homogeneous reaction medium consisting essentially of an apolar aprotic organic solvent and an alkali metal base.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: October 5, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Dung, Felix Mueller, Arno Boehm, Willi Helfer, Volker Weyrauch, Georg Henning
  • Patent number: 7780743
    Abstract: The invention relates to the dyeing of keratin materials using naphthylimide thiol/disulphide thiol fluorescent dyes, and to a dyeing process which has a lightening effect on keratin materials, in particular keratin fibres, especially human keratin fibres such as the hair, using said composition. It similarly relates to novel thiol/disulphide fluorescent dyes and to uses thereof in lightening keratin materials. This composition makes it possible to obtain a particularly resistant and visible lightening effect on dark keratin fibres.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: August 24, 2010
    Assignee: L'Oreal S.A.
    Inventors: Andrew Greaves, Nicolas Daubresse
  • Publication number: 20100168428
    Abstract: The present invention generally relates to environment-sensitive fluorophores, including environment-sensitive fluorophores for reporting protein/protein and peptide/protein interactions. In one aspect, the present invention is directed to compounds and salts thereof, compositions and methods useful in determining biological interactions. In some cases, the compounds of the present invention are environment-sensitive fluorophores that have spectroscopic behavior that may depend on factors such as the physicochemical properties of the surrounding environment. The compounds of the present invention can be used, in certain embodiments, to monitor ions, small molecules, and biological processes such as protein folding, protein-protein interactions and phosphorylation events.
    Type: Application
    Filed: February 26, 2008
    Publication date: July 1, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Barbara Imperiali, Galen S. Loving
  • Publication number: 20100158798
    Abstract: The present invention embraces compounds selected for interacting with the Fingers-Palm pocket of telomerase and use thereof for modulating the activity of telomerase and preventing or treating diseases or conditions associated with telomerase.
    Type: Application
    Filed: February 8, 2010
    Publication date: June 24, 2010
    Inventor: Emmanuel Skordalakes
  • Publication number: 20100137600
    Abstract: This invention describes reagent precursors and methods for chemical and biochemical reactions. These reagent precursors that can be activated in solution upon irradiation to generate reagents required for the subsequent chemical reactions. Specifically, photogenerated reagents (PGR) are useful for controlling parallel combinatorial synthesis and various chemical and biochemical reactions.
    Type: Application
    Filed: May 18, 2009
    Publication date: June 3, 2010
    Inventors: Xiaolian Gao, Zhuo Xiaochruan, Wu Yao, Jean-Phillipe Pollols
  • Patent number: 7714044
    Abstract: A description is given of the use of naphthalene-1,8-dicarboxylic monoimides of the formula (I), in which R1 is hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl or heteroaryl and R2 is a radical containing at least one ? electron system containing a carbon atom and at least one further atom selected from carbon, oxygen, and nitrogen, with the proviso that the radical contains at least one atom other than carbon; to protect organic material from the damaging effects of light, of compositions which comprise at least one naphthalene-1,8-dicarboxylic monoimide of the formula (I) in an amount which provides protection from the damaging effects of light, and at least one organic material, and of new naphthalene-1,8-dicarboxylic monoimides (I).
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: May 11, 2010
    Assignee: BASF Akitengesellschaft
    Inventors: Simon Schambony, Alban Glaser, Ruediger Sens, Arno Boehm, Helmut Reichelt
  • Publication number: 20100028807
    Abstract: An imide compound represented by the formula (I): wherein R1 represents a C1-C20 aliphatic hydrocarbon group etc., W1 represents —CO—O— etc., Q1 and Q2 each independently represent a fluorine atom etc., and A represents a group represented by the formula (I-1): wherein A1 represents —CH2—CH2— etc., and a chemically amplified resist composition containing the same.
    Type: Application
    Filed: July 21, 2009
    Publication date: February 4, 2010
    Applicant: SUMITOMO CHEMICAL COMPANY, LTD.
    Inventors: Ichiki TAKEMOTO, Tatsuro MASUYAMA, Takashi HIRAOKA
  • Publication number: 20100016593
    Abstract: The present invention provides crystalline forms of Palonosetron hydrochloride, processes for their preparation and pharmaceutical compositions containing such crystalline forms of Palonosetron HCl.
    Type: Application
    Filed: October 23, 2007
    Publication date: January 21, 2010
    Inventors: Pierluigi Rossetto, Peter Lindsay McDonald, Gaia Banfi, Csilla Nemethne Racz
  • Publication number: 20090320216
    Abstract: The invention relates to the dyeing of keratin materials using napthylimide thiol/disulphide thiol fluorescent dyes, and to a dyeing process which has a lightening effect on keratin materials, in particular keratin fibres, especially human keratin fibres such as the hair, using said composition. It similarly relates to novel thiol/disulphide fluorescent dyes and to uses thereof in lightening keratin materials. This composition makes it possible to obtain a particularly resistant and visible lightening effect on dark keratin fibres.
    Type: Application
    Filed: March 23, 2007
    Publication date: December 31, 2009
    Inventors: Andrew Greaves, Nicolas Daubresse
  • Publication number: 20090270440
    Abstract: The invention relates to the use of N,N?-dihydroxyamidine (I), N,N?-dihydroxyamidine ether (II), N,N?-dihydroxyamidine diether (III), N,N?-dihydroxyamidine ester (IV), N,N?-dihydroxyamidine diester (V) or 4-hydroxy-1,2,4-oxadiazoline (VI) of the formulae cited above, wherein R represents hydrogen, an alkyl and/or aryl radical, as a substitute for an amidine function of a medicament for improving the bioavailability of the medicament.
    Type: Application
    Filed: July 10, 2007
    Publication date: October 29, 2009
    Applicant: Drite Patentportfolio Beteilligungsgesellschaft mbH & Co. KG
    Inventors: Bernd Clement, Christiane Reeh
  • Publication number: 20090270593
    Abstract: A nucleic acid binding substance having an affinity for nucleic acid polymers.
    Type: Application
    Filed: April 10, 2009
    Publication date: October 29, 2009
    Inventors: David B. Bailey, Charles DeBoer, John M. Noonan, Richard S. Murante
  • Publication number: 20090203728
    Abstract: The invention relates to compounds for use in medicine.
    Type: Application
    Filed: March 31, 2005
    Publication date: August 13, 2009
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Surana Uttam, Vaidehi Krishnan, Anthony Ting, Hong Hwa Lim
  • Publication number: 20090036480
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylen substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Application
    Filed: December 27, 2005
    Publication date: February 5, 2009
    Inventors: Antoni Torrens Jover, Susana Yenes Minguez, Josep Mas Prio, Luz Romero Alonso, Alberto Dordal Zueras, Helmut Henrich Buschmann
  • Publication number: 20080275154
    Abstract: The present invention provides a radical generator having a naphthalimide structure or a crosslinking agent and a photosensitive compound having a function as a radical generator. A photoradical polymerization initiator of the present invention comprises a compound (a) having only one naphthalimide structure-containing group in one molecule. The radial generator of the present invention comprises a compound (c) having two or more naphthalimide structure-containing groups in one molecule and also functions as a crosslinking agent. A first photosensitive compound of the present invention comprises a compound (d) having a naphthalimide structure-containing group and an ethylenic unsaturated group in one molecule. A second photosensitive compound of the present invention comprises a polymer (e) of one or more radical polymerizable compounds containing the compound (d).
    Type: Application
    Filed: July 2, 2008
    Publication date: November 6, 2008
    Inventor: Katsuya SAKAYORI
  • Publication number: 20080241416
    Abstract: A polymerizable compound represented by the following formula (1): wherein, in the formula (1), R1 represents any one of a hydrogen atom, a substituted alkyl group, and an unsubstituted alkyl group; R2 represents an alkylene group; W represents any one of —CO—, —C(?O)O—, —CONH—, —OC(?O)—, and a phenylene group; X represents any one of —CO—, —NHCO—, —OC(?O)—, —CH(OH)CH2—, and —SO2—; R3 and R4 represent a monovalent substituent; R3 and R4 may be bound to each other to form a ring structure; and m and n each independently represent 0 or 1.
    Type: Application
    Filed: March 20, 2008
    Publication date: October 2, 2008
    Applicant: FUJIFILM Corporation
    Inventors: Norihide SHIMOHARA, Hisato Nagase, Shigetomo Tsujihata
  • Publication number: 20080221147
    Abstract: The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75NTR comprises, particularly when bound to nerve growth factor, at least two of the following: (1) a first electronegative atom or functional group positioned to interact with Lys34 of nerve growth factor; (2) a second electronegative atom or functional group positioned to interact with Lys95 of nerve growth factor; (3) a third electronegative atom or functional group positioned to interact with Lys88 of nerve growth factor; (4) a fourth electronegative atom or functional group positioned to interact with Lys32 of nerve growth factor; and (5) a hydrophobic moiety which interacts with the hydrophobic region formed by Ile31, Phe101 and Phe86 of nerve growth factor.
    Type: Application
    Filed: April 8, 2008
    Publication date: September 11, 2008
    Inventors: Gregory M. Ross, Igor L. Shamovsky, Sandra Marone, Donald F. Weaver, Richard J. Riopelle
  • Patent number: 7410746
    Abstract: The present invention provides a radical generator having a naphthalimide structure or a crosslinking agent and a photosensitive compound having a function as a radical generator. A photoradical polymerization initiator of the present invention comprises a compound (a) having only one naphthalimide structure-containing group in one molecule. The radial generator of the present invention comprises a compound (c) having two or more naphthalimide structure-containing groups in one molecule and also functions as a crosslinking agent. A first photosensitive compound of the present invention comprises a compound (d) having a naphthalimide structure-containing group and an ethylenic unsaturated group in one molecule. A second photosensitive compound of the present invention comprises a polymer (e) of one or more radical polymerizable compounds containing the compound (d).
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: August 12, 2008
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventor: Katsuya Sakayori
  • Publication number: 20080161569
    Abstract: A process for preparing perylene-3,4:9,10-tetracarboxylic dianhydride, comprising: dimerizing a naphthalene-1,8-dicarboximide of the formula IIa; reoxidizing the resulting alkali metal salt of the leuco form of the perylene-3,4:9,10-tetracarboxylic diimide of the formula Ia; hydrolyzing the diimide to the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid in the presence of an inert organic solvent, of an alkali metal base and of water; and subjecting the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid to the action of an aqueous inorganic acid to convert it into perylene-3,4:9,10-tetracarboxylic dianhydride; wherein R3 is cyclohexyl or phenyl which may each be substituted by up to three C1-C4-alkyl radicals, and the dimerizing is in a substantially homogeneous reaction medium consisting essentially of an apolar aprotic organic solvent and an alkali metal base.
    Type: Application
    Filed: December 13, 2007
    Publication date: July 3, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Bernhard DUNG, Felix Mueller, Arno Bohm, Willi Helfer, Volker Weyrauch, Georg Henning
  • Patent number: 7393956
    Abstract: A process for preparing perylene-3,4:9,10-tetracarboxylic diimides of the general formula I comprising dimerizing a naphthalene-1,8-dicarboximide of the formula II in a reaction medium consisting essentially of an apolar aprotic organic solvent and an alkali metal base and subsequently reoxidizing the resulting alkali metal salt of the leuco form of the perylene-3,4:9,10-tetracarboxylic diimide in the presence of a polar solvent.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: July 1, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Dung, Felix Mueller, Arno Boehm, Willi Helfer, Volker Weyrauch, Georg Henning
  • Patent number: 7358362
    Abstract: A process for preparing terylene-3,4:11,12-tetracarboximides I where the variables are each defined as follows: R, R? are each independently hydrogen; if desired substituted alkyl or cycloalkyl; R1 is hydrogen or alkyl; R2 is hydrogen; alkyl; if desired substituted aryl or hetaryl, by reacting a perylene-3,4-dicarboximide II in the presence of a base-stable, high-boiling organic solvent and of an alkali metal or alkaline earth metal base, with a naphthalene-1,8-dicarboximide III in which X is hydrogen, bromine or chlorine.
    Type: Grant
    Filed: January 15, 2005
    Date of Patent: April 15, 2008
    Assignees: BASF Aktiengesellschaft, Maz-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Martin Koenemann, Arno Boehm, Willi Helfer, Juergen Romeis, Jianqiang Qu, Klaus Muellen
  • Patent number: 7282575
    Abstract: A compound represented by the general formula (I) below: In the formula, A is as defined in the specification and B denotes where n is an integer of 1 to 4, and a process for producing the above compound includes a reaction between an activated ester and a t-butoxycarbonylaminoethylamine or an ?-amino acid derivative.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: October 16, 2007
    Assignee: Credia Japan Co., Ltd.
    Inventors: Hisafumi Ikeda, Isao Saito, Fumihiko Kitagawa
  • Patent number: 7217465
    Abstract: A light-emitting compound that can be easily applied to vacuum vapor deposition and exhibit long wavelength light is disclosed. Further, a light-emitting element without inferior luminescence properties due to the carbonization of a light-emitting compound during vapor deposition; and a light-emitting device that is composed of the light-emitting elements are also disclosed. A pyran derivative is represented by the following general formula 1: wherein R1 is a hydrogen element or an alkoxy group.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: May 15, 2007
    Assignee: Semicondutor Energy Laboratory Co., Ltd.
    Inventors: Sachiko Yamagata, Hiroko Abe, Nobuharu Ohsawa, Ryoji Nomura, Satoshi Seo
  • Patent number: 7148352
    Abstract: The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75NTR comprises, particularly when bound to nerve growth factor, at least two of the following: (1) a first electronegative atom or functional group positioned to interact with Lys34 of nerve growth factor; (2) a second electronegative atom or functional group positioned to interact with Lys95 of nerve growth factor; (3) a third electronegative atom or functional group positioned to interact with Lys88 of nerve growth factor; (4) a fourth electronegative atom or functional group positioned to interact with Lys32 of nerve growth factor; and (5) a hydrophobic moiety which interacts with the hydrophobic region formed by Ile31, Phe101 and Phe86 of nerve growth factor.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: December 12, 2006
    Assignee: Queen's University at Kingston
    Inventors: Gregory M. Ross, Igor L. Shamovsky, Sandra Marone, Donald F. Weaver, Richard J. Riopelle
  • Patent number: RE39265
    Abstract: Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: September 5, 2006
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Joseph T. Strupczewski, Kenneth J. Bordeau, Edward J. Glamkowski, Yulin Chiang, Grover C. Helsley