Abstract: Novel quinolylacetic acid compounds of the formula (I): ##STR1## wherein R.sub.1 is a member selected from the group consisting of hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, and a lower alkyl group having 1 to 4 carbon atoms substituted with an aromatic group having a substituent;R.sub.2 is a member selected from the group consisting of hydrogen atom and a lower alkyl group having 1 to 4 carbon atoms;R.sub.3 is a member selected from the group consisting of hydrogen, a halogen atom, an alkyl group having 1 to 8 carbon atoms, and an alkenyl group having 2 to 8 carbon atoms;R.sub.4 and R.sub.5, carpable of cyclization, are each a member selected from the group consisting of hydrogen atom and a lower alkyl group having 1 to 4 carbon atoms;R.sub.
Abstract: Certain aminoethyl substituted 1,3-benzthiazol- and 1,3-benzoxazol-2(3H)-ones are D.sub.2 -dopamine agonists. These compounds are prepared by reacting an appropriate o-aminophenol or thiophenol with phosgene.
Abstract: Optically active enantiomers of the formula I ##STR1## where R is a group of the formulae ##STR2## R.sub.1 and R.sub.2, among others, are halogen or CF.sub.3 and Z is a carboxyl, carboxylate, carboxylic acid ester, thioester, carbonamide, carboxylic acid anilide, carbohydrazide or thioamide group, are interesting herbicides the effect of which is considerably superior to that of the optically inactive racemates.
Type:
Grant
Filed:
December 20, 1978
Date of Patent:
July 30, 1985
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Hans J. Nestler, Gerhard Horlein, Reinhard Handte, Hermann Bieringer, Friedhelm Schwerdtle, Peter Langeluddeke
Abstract: Novel substituted carboxylic acid amide compound of the formula ##STR1## wherein n is an integer from 1 to 4each R is independently selected from hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, amino, alkylamino, dialkylamino, nitro, cyano and alkoxycarbonyl; and two R radicals taken together can represent methylenedioxy, dichloromethylenedioxy or difluoromethylenedioxy,R.sup.1 is hydrogen or alkyl,R.sup.2 and R.sup.3 are individually selected from hydrogen or a radical selected from alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl, aryl and nitrogen-containing heterocycles, each of which radicals may be substituted and each of which radicals may, together with the nitrogen atom to which they are attached, form an optionally substituted, optionally partially unsaturated and optionally benzofused monocyclic or bicyclic radical, which may contain one or more further hetero-atoms, and X is oxygen or sulfur.
Type:
Grant
Filed:
August 19, 1983
Date of Patent:
April 9, 1985
Assignee:
Bayer Aktiengesellschaft
Inventors:
Heinz Forster, Wolfgang Hofer, Volker Mues, Ludwig Eue, Robert R. Schmidt
Abstract: 2-Hydroxy-3-halo-1-propanesulfonates are reacted with certain arylamines, preferably in the presence of a base such as KOH or NaOH in one or more of ethylene glycol, propylene glycol, 2-ethoxyethanol and the like to give 2-hydroxy-3-(arylamino)-1-propanesulfonates useful as couplers for acid dyes for polyamide fibers. The present coupler products which are derivatives of aniline, tetrahydroquinoline, and benzomorpholine, have the general formulae ##STR1## wherein the rings may be substituted with a wide variety of substituents known to the dye art;M is NH.sub.4.sup.+ or a group IA metal, preferably Na.sup.+, or K.sup.+ ; andR.sup.3 is hydrogen or a group such as alkyl, cycloalkyl and aryl, each of which may be substituted.
Abstract: A continuous process for preparing benzothiazyl disulfide. More particularly, the invention relates to an improved continuous process for preparing benzothiazyl disulfide by oxidizing sodium mercaptobenzothiazole with chlorine under controlled conditions of pH, reactant concentrations, oxidation-reduction potential and agitation.
Abstract: This disclosure relates to 3-substituted aminoalkyl-2-benzothiazolinones which are useful as plant growth regulants. More specifically, this disclosure relates to 3-substituted aminoalkyl-2-benzothiazolinones and compositions containing said compounds and to the use of said compounds and compositions to regulate the growth of leguminous plants such as soybeans.
Abstract: Disclosed are certain herbicidally active benzoxazolyloxy benzoate derivatives, herbicidal compositions containing these compounds and the use of such compounds to control the growth of noxious plants, i.e., weeds.
Abstract: Disclosed are certain herbicidally active benzoxazolyl acetophenone oxime derivatives, herbicidal compositions containing these compounds and the use of such compounds to control the growth of noxious plants, i.e., weeds.
Abstract: The invention relates to cyclic sulphenamides of Formula I and methods for their manufacture. Also included in the invention are compositions containing said cyclic sulphenamides and methods for the use of said compounds and compositions as lipoxygenase inhibitors.
Type:
Grant
Filed:
April 14, 1982
Date of Patent:
May 29, 1984
Assignee:
Bayer Aktiengesellschaft
Inventors:
Wolf-Dieter Busse, Edmund Krauthausen, Mithat Mardin
Abstract: A process for preparing organic thioethers of formula R--S--R.sub.1 in which R is an aliphatic, aryl, arylaliphatic or heterocyclic radical and R.sub.1 is an aliphatic or arylaliphatic radical, from organic dithiocarbonates and organic halides or sulphonates, in the presence of an aqueous alkaline base and a phase transfer catalyst, at a temperature of between 50.degree. and 100.degree. C. for a time of 10-60 minutes.
Abstract: The invention relates to compounds having the formula ##STR1## wherein R is equal to hydrogen, halogen or alkyl containing 1-5 carbon atoms; X is equal to oxygen, sulfur or --NH; n is equal to the integer 1 to 6; with the proviso when X is --NH, n may not equal 6. These compounds are useful in regulating the growth of leguminous plants.
Abstract: The preparation of (optionally substituted) 2-mercaptobenzothiazole by reaction of corresponding 2-halogenoanilines with an alkali metal xanthate or alkaline earth metal xanthate or with CS.sub.2 in the presence of bases.
Type:
Grant
Filed:
March 2, 1981
Date of Patent:
February 14, 1984
Assignee:
Hoechst A.G.
Inventors:
Reinhard Handte, Lothar Willms, Ernst Blume
Abstract: A process for the manufacture of a 2(3H)-benzothiazolone compound substituted in 3-position, or of a 2(3H)-naphthothiazolone compound substituted in 3-position which comprises treating a 2(3H)-iminobenzothiazoline compound substituted in 3-position or a 2(3H)-naphthothazoline compound substituted in 3-position with an alkali metal hydroxide or alkaline earth metal hydroxide in a solvent or diluent stable to alkalis, in the absence of water or with substantial exclusion of water, and cyclizing the alkali metal or alkaline earth metal salt of the ortho-mercapto-N-phenyl- or -naphthyl-urea compound substituted at the nitrogen atom so formed, optionally without intermediate isolation, by treatment with an acid to give the 2(3H)-benzothiazolone compound substituted in 3-position or the 2(3H)-naphthothiazolone compound substituted in 3-position. The process furnishes the final products with high yield and purity; waste water problems are excluded by this process.
Abstract: A process for the manufacture of a 2-hydroxybenzothiazole compound which comprises treating a 2-aminobenzothiazole compound with an alkali metal hydroxide or alkaline earth metal hydroxide in a solvent or diluent stable to alkalis, in the absence of water or with substantial exclusion of water and cyclizing the alkali metal or alkaline earth metal salt of the ortho-mercapto-N-phenylurea compound so obtained, optionally without intermediate isolation, by treatment with an acid to give the 2-hydroxybenzothiazole compound. The process furnishes the final products with high yield and purity; waste water problems are excluded by this process.
Abstract: Imides derived from 2-thioxo-3-benzothiazoline acetic and propionic have been found to be effective as herbicides and plant growth regulants.
Abstract: 3,4-Disubstituted benzoxa(thia)zole-2-one derivatives of the formula: ##STR1## wherein R.sub.1 is a halogen atom or methyl group, R.sub.2 is a methyl or ethyl group and X and Y are individually an oxygen or sulfur atom, and their preparation and use as a fungicide.
Abstract: A new carbonate compound which is N,N'-di-succinimidyl carbonate, N,N'-diphthalimidyl carbonate or N,N'-bis(5-norbornene-2,3-dicarboxyimidyl) carbonate is produced by reacting an N-hydroxy compound of the formulaR-OHwherein R is succinimido, phthalimido or 5-norbornene-2,3-dicarboximido group, with a silylating agent, followed by reacting the resultant silylated product with phosgene, or alternatively by reacting said N-hydroxy compound with trichloromethyl chloroformate either in the molten state or in the presence of a non-polar organic solvent such as xylene.
Abstract: Lactone oxazoline reaction products of hydrocarbon substituted lactone carboxylic acids, for example, polybutyl lactone carboxylic acid, with 2,2-disubstituted-2-amino-1-alkanols, such as tris-(hydroxymethyl)aminomethane (THAM), and their derivatives are useful additives in oleaginous compositions, such as sludge dispersants for lubricating oil, or anti-rust agents for gasoline.
Abstract: A process for producing N-alkylbenzothiazolone derivatives of the formula (I), ##STR1## wherein R.sub.1 is a hydrogen, chlorine, bromine, fluorine atom or a methyl group, and R.sub.2 is an alkyl group having 1 to 5 carbon atoms, from 2-halogenobenzothiazole derivatives of the formula (II), ##STR2## wherein R.sub.1 is as defined above and X is a chlorine, bromine or fluorine atom, which is a starting material, through the intermediate of 2-alkoxybenzothiazole derivatives of the formula (III), ##STR3## wherein R.sub.1 and R.sub.2 are as defined above, or benzothiazolone derivatives of the formula (IV), ##STR4## wherein R.sub.1 is as defined above.
Abstract: Imides derived from 2-thioxo-3-benzothiazoline acetic and propionic have been found to be effective as herbicides and plant growth regulants. Imides derived from 2-thioxo-3-benzoxazoline acetic and propionic acid have been found to be effective plant growth regulants.
Abstract: Azole and azoline disulfides useful as corrosion inhibitors and antiwear agents are prepared by the halogen-induced coupling of a thiol reactant e.g., hydrocarbyl mercaptans, with a metal azole thiolate, e.g. the potassium salt of 3,5-bis-mercapto 1,2,4-thiadiazole or 2,5-bis-mercapto 1,3,4-thiadiazole in a 2-phase reaction medium comprising a mixture of a hydrocarbon and water.
Abstract: Novel 2-substituted-3-hydroxythiazolo[2,3-b]benzo-(and azabenzo)thiazolium salts, the mesoionic didehydro derivatives thereof and related compounds are disclosed, as well as the use thereof as modulators of the immune response.
Abstract: A novel process for the preparation of a hydroxyphenyl ether compound of the formula ##STR1## in which R represents a radical of the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are independently selected from hydrogen, halogen, haloalkyl, nitro or cyano; orR represents a heterocyclic radical which optionally carries one or more substituents selected from halogen, halogenoalkyl, alkoxy, nitro and cyano and which can contain an optionally substituted fused benzene ring,which process comprises reacting a halogen compound of the formulaR--Hal (II)in whichR is defined as above, andHal is fluorine, chlorine or bromine,with a dihydroxybenzene of the formula ##STR3## in the presence of calcium hydroxide and in the presence of a polar diluent, at a temperature of from 20.degree. C. to 200.degree. C.
Abstract: Heterocyclic phenyl ethers of the formula ##STR1## in which (R).sub.n is hydrogen or up to three identical or different substituents selected from halogen, CF.sub.3, NO.sub.2, CN, alkyl, alkoxy and alkylthio, and A is oxygen, sulfur or N(C.sub.1 -C.sub.4)alkyl, provided that the --OH group is not in para-position if (R).sub.n is hydrogen and A is sulfur, are useful as starting materials for the manufacture of selective herbicides.
Abstract: The disclosure herein relates to a novel process for producing tertiary 2-haloacetamides by reacting primary or secondary 2-haloacetamides with an agent capable of generating an anion of the primary or secondary 2-haloacetamide under base conditions and alkylating the anion of the 2-haloamide with an alkylating agent; said anion is generated, for example, by electrolysis or by metals, metal hydrides, fluorides, oxides, hydroxides, carbonates, phosphates, or alkoxides.
Abstract: N-substituted benzothiazolines and benzoxazolines having the formula ##STR1## have been found to be effective as herbicides and plant growth regulants.
Abstract: A process for the preparation of a disperse methine dye containing at least one dicyanomethylidene group comprising the steps of(A) preparing an anhydrous solution of an aldehyde formed by contacting an aromatic amine, 1,2,3,4-tetrahydroquinoline or benzomorpholine compound capable of undergoing the Vilsmeier-Haack reaction with POCl.sub.3 and a N,N-di-alkylformamide wherein the alkyl moiety is 1-4 carbon atoms;(B) subsequently adding to said solution at least one equivalent of cyanoacetamide based on the equivalents of aldehyde formed in (A), thereby forming a reaction mixture of aldehyde and in situ generated malononitrile; and(C) adjusting the pH of the solution to a point sufficient for the condensation of the aldehyde and in situ generated malononitrile to occur thereby producing a disperse methine dye.