Both Rings Which Form The Spiro Are Hetero Rings Patents (Class 549/343)
  • Patent number: 4602933
    Abstract: Novel compounds of the formula ##STR1## wherein D is hydrogen, halogen, (halo)alkyl or (halo)alkoxy; R is hydrogen, alkyl or alkoxy and R.sup.1 is the hydrocarbyl residue of a saturated oxygen-heterocyclic alcohol, are useful as herbicides.
    Type: Grant
    Filed: November 13, 1984
    Date of Patent: July 29, 1986
    Assignee: Shell Oil Company
    Inventor: Kurt H. Pilgram
  • Patent number: 4602934
    Abstract: Novel compounds of the formula ##STR1## wherein D is hydrogen, halogen, (halo)alkyl or (halo)alkoxy; R is alkyl or is cycloalkyl optionally 1-substituted by alkyl or halogen and R.sup.1 is the hydrocarbyl residue of a saturated oxygen-heterocyclic alcohol, are useful as herbicides.
    Type: Grant
    Filed: November 13, 1984
    Date of Patent: July 29, 1986
    Assignee: Shell Oil Company
    Inventor: Kurt H. Pilgram
  • Patent number: 4542027
    Abstract: A compound represented by the formula ##STR1## wherein R.sup.1 is an alkali metal cation or hydrogen and which useful for increasing the feed efficiency of ruminants and for treating coccidiosis in domestic animals, especially chickens.
    Type: Grant
    Filed: February 23, 1984
    Date of Patent: September 17, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Robin D. Clark
  • Patent number: 4533553
    Abstract: Growth of cattle and swine is promoted and feed utilization efficiency increased by an improved nutrient feed containing the antibiotic of the formula ##STR1##
    Type: Grant
    Filed: November 9, 1983
    Date of Patent: August 6, 1985
    Assignee: Pfizer Inc.
    Inventors: Walter D. Celmer, Walter P. Cullen, Riichiro Shibakawa, Junsuke Tone
  • Patent number: 4510317
    Abstract: The present invention relates to a novel polyether ionophore antibiotic of the formula ##STR1## and its pharmaceutically acceptable salts . . . The compound of formula I and its salts exhibit activity as an antibacterial agent and as an anticoccidial agent.
    Type: Grant
    Filed: July 28, 1983
    Date of Patent: April 9, 1985
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Chao-Min Liu, John Westley
  • Patent number: 4431665
    Abstract: Compounds represented by the formula ##STR1## wherein R.sup.1 is an aliphatic or alicyclic hydrocarbon acyl group of two to eighteen carbon atoms and R.sup.2 is an alkali metal cation or hydrogen are useful for increasing the feed efficiency of ruminants and for treating coccidiosis in domestic animals, especially chickens.
    Type: Grant
    Filed: June 24, 1980
    Date of Patent: February 14, 1984
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arthur F. Kluge, Robin D. Clark
  • Patent number: 4410354
    Abstract: Certain spiro ether derivatives are useful as herbicides.
    Type: Grant
    Filed: February 1, 1982
    Date of Patent: October 18, 1983
    Assignee: Shell Oil Company
    Inventors: Kurt G. R. Sundelin, James E. Powell, Willy D. Kollmeyer
  • Patent number: 4408059
    Abstract: Milbemycin and avermectin macrolides are synthesized by the cyclized linking of separately synthesized northern and southern hemisphere intermediates. The northern hemisphere intermediate is a spiroketal alkenyl aldehyde, and the southern hemisphere intermediate is an aryl alkenyl phosphine oxide anion.
    Type: Grant
    Filed: December 4, 1981
    Date of Patent: October 4, 1983
    Assignee: University Patents, Inc.
    Inventors: Amos B. Smith, III, Steven R. Schow
  • Patent number: 4359583
    Abstract: The novel antibiotics represented by the formula ##STR1## wherein either (a) R.sup.1 is hydroxy and R.sup.2 is hydrogen, or (b) R.sup.1 is methoxy and R.sup.2 is hydroxy, and the salt thereof, are produced by the cultivation of the organism Streptomyces hygroscopicus TM-531 under aerobic conditions. They are separated from coproduced Antibiotic TM-531 as disclosed in U.S. Pat. No. 4,269,971 and from each other by chromatography on silica gel.
    Type: Grant
    Filed: September 15, 1981
    Date of Patent: November 16, 1982
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Taku Mizutani, Michio Yamagishi, Kazutoshi Mizoue, Akira Kawashima, Sadafumi Omura, Noboru Otake, Haruo Seto