Abstract: Novel compounds of the formula ##STR1## wherein D is hydrogen, halogen, (halo)alkyl or (halo)alkoxy; R is hydrogen, alkyl or alkoxy and R.sup.1 is the hydrocarbyl residue of a saturated oxygen-heterocyclic alcohol, are useful as herbicides.
Abstract: Novel compounds of the formula ##STR1## wherein D is hydrogen, halogen, (halo)alkyl or (halo)alkoxy; R is alkyl or is cycloalkyl optionally 1-substituted by alkyl or halogen and R.sup.1 is the hydrocarbyl residue of a saturated oxygen-heterocyclic alcohol, are useful as herbicides.
Abstract: A compound represented by the formula ##STR1## wherein R.sup.1 is an alkali metal cation or hydrogen and which useful for increasing the feed efficiency of ruminants and for treating coccidiosis in domestic animals, especially chickens.
Abstract: Growth of cattle and swine is promoted and feed utilization efficiency increased by an improved nutrient feed containing the antibiotic of the formula ##STR1##
Type:
Grant
Filed:
November 9, 1983
Date of Patent:
August 6, 1985
Assignee:
Pfizer Inc.
Inventors:
Walter D. Celmer, Walter P. Cullen, Riichiro Shibakawa, Junsuke Tone
Abstract: The present invention relates to a novel polyether ionophore antibiotic of the formula ##STR1## and its pharmaceutically acceptable salts . . . The compound of formula I and its salts exhibit activity as an antibacterial agent and as an anticoccidial agent.
Abstract: Compounds represented by the formula ##STR1## wherein R.sup.1 is an aliphatic or alicyclic hydrocarbon acyl group of two to eighteen carbon atoms and R.sup.2 is an alkali metal cation or hydrogen are useful for increasing the feed efficiency of ruminants and for treating coccidiosis in domestic animals, especially chickens.
Abstract: Milbemycin and avermectin macrolides are synthesized by the cyclized linking of separately synthesized northern and southern hemisphere intermediates. The northern hemisphere intermediate is a spiroketal alkenyl aldehyde, and the southern hemisphere intermediate is an aryl alkenyl phosphine oxide anion.
Abstract: The novel antibiotics represented by the formula ##STR1## wherein either (a) R.sup.1 is hydroxy and R.sup.2 is hydrogen, or (b) R.sup.1 is methoxy and R.sup.2 is hydroxy, and the salt thereof, are produced by the cultivation of the organism Streptomyces hygroscopicus TM-531 under aerobic conditions. They are separated from coproduced Antibiotic TM-531 as disclosed in U.S. Pat. No. 4,269,971 and from each other by chromatography on silica gel.