Plural Hetero Rings Patents (Class 549/472)
  • Patent number: 4585574
    Abstract: Anthraquinone dyestuffs of the formula ##STR1## in which R.sub.1 and R.sub.2 denote hydrogen, alkyl, cycloalkyl, aryl or aralkyl, and the said hydrocarbon radicals can be substituted, andQ denotes an aryl radical or heterocyclic radical or an --OR', --SR', --CH.dbd.N--R', ##STR2## --CHO or --SO.sub.2 --O--R' radical, whereinR' represents an aryl, aralkyl or heterocyclic radical, and the radicals mentioned for R' can be substituted,processes for their preparation, and liquid-crystalline materials containing anthraquinone dyestuffs.
    Type: Grant
    Filed: November 25, 1981
    Date of Patent: April 29, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Martin Blunck, Uwer Claussen, Rutger Neeff
  • Patent number: 4577035
    Abstract: The new composition of matter, 2,2'-isopropylidine bis(tetrahydrofuran) and method of preparation.
    Type: Grant
    Filed: November 28, 1984
    Date of Patent: March 18, 1986
    Inventors: George W. Huffman, William J. Pentz, David E. Vietti, Joseph P. Wuskell
  • Patent number: 4569996
    Abstract: This invention provides a process for the preparation of pyrimidinone compounds with a group R.sup.2 CH(OH)-- at the 5-position thereof, wherein R.sup.2 is an optionally substituted acid-stable 5- or 6-membered nitrogen-containing heteroaryl group. The pyrimidinone ring is further substituted by a side-chain of a H.sub.1 -antagonist or H.sub.2 -antagonist or a precursor thereof.The compounds are convertible to 5-heteroaryl methyl compounds which are either useful H.sub.1 - or H.sub.2 -antagonists or precursors thereof.
    Type: Grant
    Filed: July 27, 1983
    Date of Patent: February 11, 1986
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: John Kitteringham, Brian P. Slingsby
  • Patent number: 4551536
    Abstract: A class of N,N',N"-trisubstituted bis-(p-aminobenzyl) anilines are found to be effective antioxidants in a broad spectrum of petroleum and petroleum related products. N,N',N"-Tri(arylmethyl) and tri(heteroarylmethyl) substituted materials of the parent compound are especially effective at concentrations as low as about 0.0005 percent by weight.
    Type: Grant
    Filed: July 15, 1983
    Date of Patent: November 5, 1985
    Assignee: UOP Inc.
    Inventor: John T. Roberts
  • Patent number: 4550214
    Abstract: The present invention relates to vinyl biphenyl compounds of the formula ##STR1## wherein one of R.sup.1 and R.sup.2 is vinyl and the other is hydrogen, and the cyclic moiety A is a -2,5-, -2,3-, or -3,4- di-OR-1-phenyl moiety wherein R is a hydroxy-protecting group, polymers prepared therefrom, and methods of preparation thereof. The subject vinyl biphenyls can be polymerized and the resultant polymers deblocked to remove the R groups and provide the corresponding polymeric dihydroxybiphenyls which can be employed as redox polymers.
    Type: Grant
    Filed: October 19, 1983
    Date of Patent: October 29, 1985
    Assignee: Polaroid Corporation
    Inventor: Avinash C. Mehta
  • Patent number: 4548752
    Abstract: Improved rigid urethane and isocyanurate foam compositions having improved fire resistance are described. The urethane foams are based on furan compositions and are chiefly made from adding propylene oxide to bis(hydroxymethyl)furan.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: October 22, 1985
    Assignee: QO Chemicals, Inc.
    Inventor: William J. Pentz
  • Patent number: 4540788
    Abstract: This disclosure describes novel Schiff bases of 1,4-bis[(.omega.-aminoalkyl)amino]-9,10-anthracenediones and leuco bases thereof which are useful as chelating agents and for inducing regression of leukemia and/or inhibiting tumor growth in mammals.
    Type: Grant
    Filed: July 14, 1983
    Date of Patent: September 10, 1985
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • Patent number: 4539332
    Abstract: Analogs of 2,5-Diaryl tetrahydrofurans which were substituted or unsubstituted at 3,4-positions were prepared.These compounds are found to have potent and specific PAF (Platelet Activating Factor) antagonistic activities and thereby useful in the treatment of various diseases or disorders mediated by the PAF, for example, inflammation, cardiovascular disorder, asthma, lung edema, adult respiratory distress syndrome, pain, and aggregation of platelets.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: September 3, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Tesfaye Biftu, San-Bao Hwang, Thomas W. Doebber, Thomas R. Beattie, Tsung-Ying Shen
  • Patent number: 4537623
    Abstract: Herbicidal 2-(oxaheterocycle or thiaheterocycle)-5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofurans and derivatives thereof. The compounds generally exhibit both pre-emergence and post-emergence phytotoxicity and are useful as herbicides and also plant growth regulating agents at low dosages.
    Type: Grant
    Filed: March 29, 1984
    Date of Patent: August 27, 1985
    Assignee: Chevron Research Company
    Inventor: Carl E. Ward
  • Patent number: 4514406
    Abstract: A compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are, same or different, each a hydrogen atom, a C.sub.1 -C.sub.3 alkyl group optionally substituted with halogen, an alkoxyalkyl or alkylthioalkyl group of the formula: R.sub.7 --Z--(CH.sub.2).sub.q --, a C.sub.2 -C.sub.3 alkenyl group, a C.sub.2 -C.sub.4 alkynyl group, a C.sub.1 -C.sub.2 alkoxy group, a C.sub.1 -C.sub.2 alkylthio group, a phenyl group, a pyridyl group, a furyl group or a thienyl group, or R.sub.1 and R.sub.2 may be combined together to form a saturated or unsaturated 5- or 6-membered ring having 0 to 2 oxygen or sulfur atom(s) within the ring, R.sub.3 and R.sub.4 are, same or different, each a hydrogen atom or a methyl group, R.sub.5 is a methyl group or a halogen atom, R.sub.6 is a C.sub.1 -C.sub.4 alkyl group, a methoxy group, a halogen atom, a trifluoromethyl group or a nitro group, R.sub.
    Type: Grant
    Filed: February 16, 1983
    Date of Patent: April 30, 1985
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Tadashi Ohsumi, Makoto Hatakoshi, Hirosi Kisida
  • Patent number: 4499311
    Abstract: The effluent stream from a process for producing phenolic compounds is reacted with an aldehyde in the presence of a base to form a water soluble resol which is useful in enhanced oil recovery.
    Type: Grant
    Filed: December 2, 1982
    Date of Patent: February 12, 1985
    Assignee: General Electric Company
    Inventors: Clifford L. Spiro, Edward J. Lamby
  • Patent number: 4496751
    Abstract: Compounds of the formula (I) ##STR1## in which R.sub.1 and R.sub.2 are the same or different and are selected from hydrogen, substituted or unsubstituted methyl or ethyl radicals, and substituted or unsubstituted vinyl radicals, X is a --NH.sub.2 or --NCO group, and n is 0 or 1 with the proviso that n is not 0 when X is --NH.sub.2.
    Type: Grant
    Filed: April 1, 1983
    Date of Patent: January 29, 1985
    Assignee: The University of Manchester Institute of Science & Technology
    Inventors: Richard H. Still, John L. Cawse, John L. Stanford
  • Patent number: 4481310
    Abstract: Acid-curable, condensation-type resins, particularly phenolic resin prepolymers and urea-formaldehyde and/or furfuryl alcohol-formaldehyde modified phenolic resin prepolymers, have improved properties when admixed with a dibasic acid di-ester of the compositionR.sup.1 O.sub.2 C(CH.sub.2).sub.n CO.sub.2 R.sup.2where n is from 1 to 8, R.sup.1 is furfuryl, and R.sup.2 is furfuryl or methyl. The di-esters are preferably added in the amount of 5-35%, by weight of total composition. These compositions are particularly useful in the preparation of sand cores and molds for foundry use which have improved strength and hardness.The dibasic acid di-esters of the compositionR.sup.1 O.sub.2 C(CH.sub.2).sub.n CO.sub.2 R.sup.2where n is from 1 to 8, R.sup.1 is furfuryl, and R.sup.2 is furfuryl or methyl are not reported in the literature and are novel compounds. These di-esters are oily liquids having high boiling points and are particulary useful as resin modifiers, diluents and plasticizers.
    Type: Grant
    Filed: June 14, 1983
    Date of Patent: November 6, 1984
    Assignee: CL Industries, Inc.
    Inventor: Wayne D. Woodson
  • Patent number: 4477678
    Abstract: Novel thioether compounds are disclosed which are useful as flavoring materials to enhance or impart meat-like flavors to foodstuffs. These compounds have the general formula ##STR1## where X can be, under specified conditions, --CH.sub.2 --, oxygen, or sulfur, Y can be oxygen or sulfur and R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are hydrogen or 1 to 3 carbon alkyl groups.
    Type: Grant
    Filed: January 4, 1983
    Date of Patent: October 16, 1984
    Assignee: P.F.W. Beheer B.V.
    Inventors: Steven van den Bosch, Dirk K. Kettenes, Kris B. de Ross, Gerben Sipma, Jan Stoffelsma
  • Patent number: 4456586
    Abstract: Non-ionic surface-active agents of the formula are disclosed: ##STR1## in which a=0 or 1, R denotes a C.sub.8 -C.sub.30 aliphatic or alicyclic radical, x+y totals a number from 1 to 10 and, in each unit, one of Z.sub.1 and Z.sub.2 denotes hydrogen and the other denotes the radical ##STR2## in which R.sub.1 denotes methyl or ethyl. These products can be prepared simply and are suitable for use in cosmetic or pharmaceutical compositions and in particular in cosmetic compositions for treating the hair or skin.
    Type: Grant
    Filed: October 23, 1981
    Date of Patent: June 26, 1984
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag, Rene Pierre
  • Patent number: 4450217
    Abstract: Novel chalcogenopentalene compounds having a tellurium atom in the 6a position, and methods of making chalcogenopentalenes having a tellurium or a selenium atom in the 6a position are disclosed. The chalcogenopentalene compounds are useful as sensitizers in electrophotographic compositions and elements containing an electron donor and as charge emitters in multilayer photoconductive elements.
    Type: Grant
    Filed: March 15, 1983
    Date of Patent: May 22, 1984
    Assignee: Eastman Kodak Company
    Inventors: Michael R. Detty, Jerome H. Perlstein
  • Patent number: 4439225
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are H or alkyl; n is 0 or 1 and R is an unsaturated moiety, are useful as herbicides and plant growth regulators.
    Type: Grant
    Filed: June 14, 1982
    Date of Patent: March 27, 1984
    Assignee: Shell Oil Company
    Inventor: Willy D. Kollmeyer
  • Patent number: 4417064
    Abstract: The present invention relates to novel biphenyl compounds of the formula ##STR1## wherein one of R.sup.1 and R.sup.2 is hydrogen and the other is --CH.sub.3-m X.sub.m wherein X is chloro or bromo and m is an integer one or two, and the cyclic moiety A is a -2,5-; -2,3-; or -3,4-di-OR-1-phenyl moiety wherein R is a hydroxy-protecting group and to a method of preparing same. The biphenyl compounds are useful as intermediates in preparing redox compounds containing a phenylhydroquinone or phenylcatechol moiety.
    Type: Grant
    Filed: October 22, 1981
    Date of Patent: November 22, 1983
    Assignee: Polaroid Corporation
    Inventor: Avinash C. Mehta
  • Patent number: 4417072
    Abstract: Substituted hydroquinone compounds of the formula ##STR1## wherein R.sub.1 to R.sub.4 are hydrogen or alkyl and Z is an aromatic ring or a group of the formula --X--Y--X--, wherein X is an aromatic ring and Y is an electron withdrawing group, are incorporated as developers into photographic materials. These materials are suitable for activation processings.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: November 22, 1983
    Assignee: Ciba-Geigy AG
    Inventors: Stephen R. Postle, Patrick D. P. Thomas, Brian R. D. Whitear
  • Patent number: 4405461
    Abstract: A method and product for use in controlling the deposition of silica-containing scales and their adhesion to the walls of piping and other plant components. The product is an amine to which is attached at least a pair of terminal groups. Each group is selected from the family of compounds consisting of furfuryl and a saturated or unsaturated hydrocarbon radical substituted with one or more members selected from hydroxy and carboxy, or a hydrohalide thereof. The method includes injecting the additive into saline brine or brackish water containing silica which may tend to precipitate as a scale.
    Type: Grant
    Filed: March 26, 1982
    Date of Patent: September 20, 1983
    Inventor: Alfred N. Rogers
  • Patent number: 4389526
    Abstract: Novel methods are provided for synthesizing 2-amino-2-tetritol, by positive halogen addition to protected 1,4-dioxybutene-2 in the presence of a nitrile, resulting in addition of a halo functionality and the nitrile functionality across the double bond. Upon hydrolysis, the desired erythro-product can be obtained in stereochemically good yield.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: June 21, 1983
    Assignee: The Regents of the University of California
    Inventors: Milos Sovak, Ramachandran Ranganathan
  • Patent number: 4388469
    Abstract: Diphenylalkanoether and diphenylalkanone oxime-ether derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each independently an aryl group optionally substituted with 1 to 3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, cyano, di(C.sub.1 -C.sub.4)alkylamino, amino, benzyloxy, hydroxyl, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfinyl, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 alkanoylamino, C.sub.1 -C.sub.4 alkylamino and N-(C.sub.1 -C.sub.4)alkyl-N-(C.sub.1 -C.sub.4)alkanoylamino, Z.sup.1 is a group of the formula: ##STR2## (wherein R.sup.3 and R.sup.4 are each independently a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or an ar(C.sub.1 -C.sub.
    Type: Grant
    Filed: April 2, 1980
    Date of Patent: June 14, 1983
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Keiichi Ono, Hajime Kawakami, Junki Katsube
  • Patent number: 4380655
    Abstract: Novel thioether compounds are disclosed which are useful as flavoring materials to enhance or impart meat-like flavors to foodstuffs. These compounds have the general formula ##STR1## where X can be, under specified conditions, --CH.sub.2 --, oxygen, or sulfur, Y can be oxygen or sulfur and R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are hydrogen or 1 to 3 carbon alkyl groups.
    Type: Grant
    Filed: May 22, 1978
    Date of Patent: April 19, 1983
    Assignee: P.F.W. Beheer B.V.
    Inventors: Steven van den Bosch, Dirk K. Kettenes, Kris Bart de Roos, Gerben Sipma, Jan Stoffelsma
  • Patent number: 4370488
    Abstract: The invention includes novel alkali metal complex compounds (and processes for their preparation) which are useful, inter alia for the hydrogenation of alkali metals at room temperature or below room temperature to form hydrides or nitrides.
    Type: Grant
    Filed: June 18, 1981
    Date of Patent: January 25, 1983
    Assignee: Studiengesellschaft Kohle mbH
    Inventor: Borislav Bogdanovic
  • Patent number: 4367340
    Abstract: Compounds of the general formula I are disclosed as useful intermediates in the preparation of prostanoids: ##STR1## wherein A represents O or H, OR.sub.z ;R.sup.z represents hydrogen or a protecting group;R.sup.x represents hydrogen or a protecting group; andR.sup.y represents halogen, a substituted thio group, di-substituted amino group, or a group of the formula R.sup.2, and R.sup.2 represents a straight-or branched-chain alkyl alkenyl or alkynyl group which may optionally be substituted by one or more carboxyl, carboxylic acid ester, or free or protected hydroxyl, thiol, aldehyde or keto groups;with the provisos that R.sup.x is not hydrogen when A is O and R.sup.y is R.sup.2 ; and that when A is H, OR.sup.z R.sup.y is R.sup.2 and R.sup.x and R.sup.z are not both hydrogen.Processes for the preparation of these compounds and of 2-substituted 4-hydroxy-cyclopent-2-en-1-one derivatives are also disclosed.
    Type: Grant
    Filed: March 4, 1981
    Date of Patent: January 4, 1983
    Assignee: The Australian National University
    Inventors: Rodney W. Rickards, Melvyn Gill, Robert M. Christie
  • Patent number: 4340543
    Abstract: Sulfonium compounds represented by the formula ##STR1## have anticancer activity, immunostimulant activity and the like, and useful as the active components of drugs and agricultural chemicals.
    Type: Grant
    Filed: February 3, 1981
    Date of Patent: July 20, 1982
    Assignee: Taiho Pharmaceutical Company Limited
    Inventors: Akihide Koda, Mikio Hori, Mitsugi Yasumoto, Ichiro Yamawaki, Yuji Yamada, Katsuo Takikawa
  • Patent number: 4334073
    Abstract: Process for the preparation of an alpha-hydroxycarboxylic acid amide compound of the formula ##STR1## wherein R.sup.1 is hydrogen or alkyl; andR.sup.2 and R.sup.3 are individually selected from hydrogen, alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl or aryl, each of which may be optionally substituted, or a nitrogen-containing heterocyclic radical; orR.sup.2 and R.sup.3, together with the nitrogen atom to which they are bonded, represent an optionally benzo-fused monocyclic or bicyclic ring, which ring may be substituted and may be partially unsaturated,which process comprises reacting in a first stage an alpha-halocarboxylic acid amide of the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are identified as above; andHal is chlorine or bromine,with an alkali metal acetate or alkaline earth metal acetate in the presence of a quaternary ammonium salt at a temperature between 20.degree. and 200.degree. C.
    Type: Grant
    Filed: December 1, 1980
    Date of Patent: June 8, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventor: Hans-Joachim Diehr
  • Patent number: 4328167
    Abstract: A novel process for the preparation of optically active alcohols of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, saturated and unsaturated, optionally substituted aliphatic, cycloaliphatic, aromatic and heterocyclic, with the proviso that at least one of R.sub.1 and R.sub.2 is other than hydrogen, and R.sub.1 and R.sub.2 taken together with the carbon atom to which they are attached form a hydrocarbon ring comprising reacting an ester of an optically active alcohol of the formula ##STR2## wherein A is the organic radical of a chiral carboxylic acid of the formula ##STR3## with a boron halide and reacting the resulting mixture with water to obtain the optically active isomer of the alcohol of formula I with the same configuration of the alcohol moiety of the starting ester in high yields without by-products of known processes.
    Type: Grant
    Filed: June 2, 1980
    Date of Patent: May 4, 1982
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Tessier, Jean-Pierre DeMoute
  • Patent number: 4328168
    Abstract: This invention provides a convenient and commercially adaptable process for the preparation of vinylcyclopropane derivatives in high yield. For the process an alkylating agent and activated methylene compound are reacted in the presence of a cyclic polyether compound and alkali metal compound. Water can also be present and/or the reaction may be carried out in an inert organic diluent.
    Type: Grant
    Filed: October 27, 1980
    Date of Patent: May 4, 1982
    Assignee: Emery Industries, Inc.
    Inventor: Richard G. Fayter, Jr.
  • Patent number: 4328169
    Abstract: This invention provides a convenient and commercially adaptable process for the preparation of vinylcyclopropane derivatives in high yield. For the process an alkylating agent and activated methylene compound are reacted in the presence of an alkylene oxide derivative and alkali metal compound. Water can also be present and/or the reaction may be carried out in an inert organic diluent.
    Type: Grant
    Filed: October 27, 1980
    Date of Patent: May 4, 1982
    Assignee: Emery Industries, Inc.
    Inventor: Allen L. Hall