Abstract: Disclosed are novel substituted cyclohexenyl phosphinylhydroxybutyrates as 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula: ##STR1## and pharmaceutically acceptable salts thereof.

Abstract: Halogenated 9-phosphonoalkyl derivatives of guanine and hypoxanthine are inhibitors of purine nucleoside phosphorylase and are useful as immuno suppressant and antiparasitic agents as well as against T cell leukemia and antiureicopoietic agents.

Abstract: Esters of trihydric or tetrahydric alcohols with alkenylphosphonic or -phosphinic acids, which can be polymerized by means of actinic light, are disclosed. They are combined with polymeric binders, in particular water-soluble polymers, and free-radical-forming photoinitiators to form photopolymerizable mixtures which are suitable for the preparation of photoresists and the production of printing plates. The mixtures show reduced temperature sensitivity and have long shelf lives.

Abstract: New chemical product, constituted by an organic phosphorus compound of the structure ##STR1## where Q is an N or O atom, T is an alkylene or arylene, possibly carrying substituents, or not existing, while R.sup.1 to R.sup.7, the same or different, are H or aliphatic, cycloaliphatic and/or arylic hydrocarbon radicals, possibly substituted, R.sup.3 not existing when Q is oxygen.This product is used as an intermediate in the preparation of different derivatives of phosphinous acid.

Abstract: Novel substituted N-alkyl-N-alkoxyamidophosphonates or -thiophosphonates and N-alkyl-N-alkoxyamidophosphates or -thiophosphates of formula ##STR1## wherein R is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy,R.sub.1 and R.sub.3 are each independently of the other C.sub.1 -C.sub.4 alkyl,R.sub.2 is hydrogen, C.sub.4 -C.sub.4 alkyl, or when taken together with R.sub.1, forms the radical --(CH.sub.2).sub.4 --; andX and Y are each independently of the other oxygen or sulfur, with the proviso that at least one of X or Y is sulfur if R.sub.2 is hydrogen.The preparation of these compounds is described, as well as the use thereof in pest control, especially for controlling insects and representatives of the order Acarina.

Abstract: Hydrocarbon compositions, including oligomers and polymers, for use in improving the thermo-oxidative stability and the dispersancy and viscosity index improvement (for high molecular weight) properties of fuels and lubricating oils are disclosed. These compositions are adducts of sulfur mono- and diimides having one of the following formulae: ##STR1## wherein r is a hydrocarbyl containing at least 18 carbon atoms, in which X.dbd. can be O.dbd., S.dbd., Y'--N.dbd., i is 0 or 1, --Y and Y'-- can be ##STR2## wherein R' is hydrocarbyl or hydrocarbyloxy, R" is hydrocarbyl, R'" and R"" are hydrocarbyloxy, and each of R', R", R'", and R"" is from 1 to 20 carbon atoms.

Abstract: Novel (halo)(hydroxy)-substituted phosphorus-containing acid derivatives are disclosed. Preferred compounds are 2-halo-3-hydroxypropyl ester derivatives of phosphorus and phosphoric acid formed by reaction of at least some amount of tertiary butyl glycidyl ether with a halogenated derivative of a phosphorus-containing acid followed by acid dealkylation of the product. The polyol products are useful in the production of polyurethane articles such as foams having increased resistance to the effects of fire. The derivatives can be additives or reactants in the polyurethane, depending on the presence or absence of terminal hydroxyl groups within the given ester moieties.

Abstract: Novel phosphoric esters of the general formula ##STR1## in which X represents a halogen, R.sub.1 represents a linear or branched alkyl, fluoroalkyl or alkenyl group having from 1 to 36 carbon atoms, or a phenyl group substituted with a linear or branched alkyl group having from 1 to 15 carbon atoms, R.sub.2 represents an alkylene group having 2 or 3 carbon atoms, n is a value of from 0 to 30, and M represents a hydrogen atom, alkali metal, alkaline earth metal, ammonium, or an alkylamine or alkanolamine salt are prepared by reacting a salt of a phosphoric monoester of the general formula (II) ##STR2## in which R.sub.1, R.sub.2 and n have, respectively, the same meanings as defined above, and M.sub.1 represents an alkali metal, with an epihalohydrin of the general formula (III) ##STR3## in which X has the same meaning as defined above, and optionally, converting the resulting product into a free acid or a different salt.

Abstract: The mannite derivatives have the formula (1) wherein R' and R.sup.2, idenal or different, represent when they are identical a straight or branched alkyl, alkenyl or alkynyl group containing from 5 to 24 atoms of carbon which may be substituted by a cycloalkyl residue having from 3 to 6 atoms of carbon, an aryl, benzyloxy, allyloxy, mesyloxy residue and/or halogen atoms and when R' and R.sup.2 are different, they represent a straight or branched alkyl group with 1 to 24 atoms or carbon, which may be substituted by a cycloalkyl residue having from 3 to 6 atoms of carbon, an aryl, benzyloxy, allyloxy, mesyloxy residue and/or halogen atoms, with the possibility for R' of being also a trityl group. From said mannite derivatives, it is possible to obtain in a simple way and with good yields the phospholipids in the form of their optical stereo isomers.

Abstract: Reaction products of 5-norbornene-2,3-dicarboxylic anhydride O,O-dialkyldithiophosphate adduct of the formula ##STR1## have been found to be beneficial additives for functional fluids used in the machinery of motorized vehicles. These additives are effective extreme pressure agents and antiwear agents as well as antioxidants for use in such functional fluids as lubricating oils including automatic transmission fluids and hydraulic fluids.

Abstract: The reaction product of a long chain vicinal diol containing at least 10 carbon atoms and at least one sulfur atom in the chain, with dihydrocarbyl hydrogen phosphites are effective friction reducing antiwear additives in lubricating oils, greases and fuels.

Abstract: This invention relates to novel substituted 2-hydroxy-2-phosphinyl ethanals of the general Formula I. ##STR1## to 1,2-dihydroxy-1,2-bisphosphinylethanes of the general Formula II ##STR2## to methods of making the same, to compositions containing compounds of the general Formula I, and/or of the general Formula II, to the use of such compositions to impart flame-resistance to cellulose and cellulose containing materials, to flame-resistant compositions containing compounds of the general Formula II and to the use of the compounds of the general Formula II as metal complexing agents.In the compounds of the Formulas I and II R.sub.1 and R.sub.2 may be the same or different radicals including alkoxy, aryloxy, arylalkoxy, cycloalkoxy, alkyl, alkenyl, aryl, aralkyl, cycloalkyl as well as such radicals containing substituents such as halogen, amino, hydroxy, alkoxy, mercapto, carboxy, carbalkoxy and the like in addition R.sub.1 and/or R.sub.2 may be hydroxy.

Abstract: Amine, diamine and triamine salts of diol-derived acid phosphates impart excellent friction reducing and antiwear characteristics to lubricant compositions into which they have been incorporated.