Phosphorus, And Two Chalcogens Bonded Directly Thereto, In The Same Ring (e.g., Cyclic Phosphonates, Etc.) Patents (Class 558/77)
  • Patent number: 10138355
    Abstract: A flame retardant resin composition containing 1 to 100 parts by weight of (B) an organophosphorus compound (component B) represented by the following formula (1) per 100 parts by weight of (A) a resin component (component A) containing at least 60 wt % of an acrylic resin has high flame retardancy, high transparency and satisfactory physical properties: wherein X1 and X2 are the same or different, and represent alkyl groups substituted with aromatic groups represented by the following formula (2): ALAr)n??(2) wherein AL represents a branched or linear aliphatic hydrocarbon group having 1 to 5 carbon atoms, Ar represents a phenyl group, a naphthyl group, or an anthryl group each optionally substituted, n represents an integer of 1 to 3, and Ar can be bonded to any carbon atom in AL.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: November 27, 2018
    Assignee: TEIJIN LIMITED
    Inventors: Katsuhiro Yamanaka, Tsuyoshi Takeda, Kenta Imazato
  • Patent number: 9127156
    Abstract: In one embodiment, A flame-retardant thermoplastic starch material, including (A1) 100 parts by weight of starch; (A2) 5 to 75 parts by weight of plasticizer; and (A3) 5 to 30 parts by weight of organic phosphonate flame-retardant, wherein the organic phosphonate flame-retardant has the following formula (I): wherein X is a trivalent aliphatic hydrocarbon radical containing 3 to 12 carbon atoms; R1 and R2 are independently C1 to C8 alkyl; and n is 0 or 1.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: September 8, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Sheng-Ju Liao, Chih-Jen Chang, Yao-Chu Chung, Fu-Ming Chien, Chien-Ming Chen
  • Publication number: 20150132607
    Abstract: Flame retardant synthetic leather having high flame retardancy and excellent physical properties (light resistance, heat resistance and feeling). The flame retardant synthetic leather contains an organic phosphorus compound (component A) represented by the following formula (1). (In the formula, X1 and X2 are the same or different and each an aromatic substituted alkyl group represented by the following formula (2).) —(AL)—(Ar)n ??(2) (In the formula, AL is a branched or linear aliphatic hydrocarbon group having 1 to 5 carbon atoms, and Ar is a phenyl group, riaphthyl group or anthryl group, all of which may have a substituent. “n” is an integer of 1 to 3, and Ar may be bonded to any carbon atom contained in AL.
    Type: Application
    Filed: June 7, 2013
    Publication date: May 14, 2015
    Applicants: TEIJIN LIMITED, MARUBISHI OIL CHEMICAL CO., LTD.
    Inventors: Katsuhiro Yamanaka, Tsuyoshi Takeda, Kuniaki Kondo, Masaki Haruyoshi
  • Publication number: 20150073169
    Abstract: A process for reducing the level of contaminant metals in ligands used in the preparation of catalysts is disclosed.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 12, 2015
    Applicant: Dow Technology Investments LLC
    Inventor: Glenn A. Miller
  • Publication number: 20140350268
    Abstract: The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Brønsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.
    Type: Application
    Filed: January 8, 2013
    Publication date: November 27, 2014
    Applicant: STUDIENGESELLSCHAFT KOHLE MBH
    Inventors: Benjamin List, Ilija Coric, Sreekumar Vellalath
  • Publication number: 20140221316
    Abstract: This disclosure relates to novel compounds containing an H2S releasing moiety and a nitric oxide (NO) releasing moiety covalently linked with a core (e.g., a salicylic acid moiety) and the use of such compounds in treating inflammatory diseases, including cancers. Therapeutic potency of these compounds is significantly higher than NSAIDs containing a H2S-releasing moiety alone (HS-NSAIDs) and NSAID containing a NO-releasing moiety alone (NO-NSAIDs). The compounds, in addition, exhibit reduced side effect, e.g., reduced stomach ulcers, upon administration.
    Type: Application
    Filed: August 15, 2012
    Publication date: August 7, 2014
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Khosrow Kashfi, Ravinder Kodela
  • Patent number: 8796389
    Abstract: The present invention relates to a method for thermal crosslinking of adhesives and also to products produced with these adhesives. An object of the invention is to provide a method for thermal crosslinking of adhesives where the crosslinking is covalent and (initiated by a chemical or physical stimulus) reversible. As and when required, the crosslinking method can also be configured to result in a covalent, irreversible network.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: August 5, 2014
    Assignee: TESA SE
    Inventors: Alexander Prenzel, Sarah Bamberg
  • Publication number: 20130317246
    Abstract: The invention relates to a process for the purification of 6,6?-[(3,3?-di-tert-butyl-5,5?-dimethoxy-1,1?-biphenyl-2,2?diyl)bis(oxy)]bis(dibenzo[d,f][1,3,2]dioxaphosphepin), abbreviation: biphephos (see formula 1).
    Type: Application
    Filed: December 22, 2011
    Publication date: November 28, 2013
    Applicant: Evonik Oxeno GmbH
    Inventors: Burkard Kreidler, Dirk Fridag, Bernhard Schemmer, Bjoern Wechsler, Andrea Christiansen, Doris Neumann
  • Patent number: 8278375
    Abstract: Mixtures of three types of linear, branched or cyclic phosphates are useful flame retardants, especially for thermoplastic resins or as functional additives in polymer matrices.
    Type: Grant
    Filed: July 5, 2006
    Date of Patent: October 2, 2012
    Assignee: Rhodia UK Limited
    Inventors: Vincent Schanen, Dwight Shamblee, Gleb Priimov, Julie Ann Salter
  • Patent number: 8222329
    Abstract: Disclosed herein is a symmetric cyclic phosphonate compound represented by the following Formula 1, a method of preparing the same and a flame retardant styrenic resin composition including the same: wherein R1 and R2 are each independently hydrogen, C1-C6 alkyl or C6-C20 aryl. The styrene resin composition employing the symmetric cyclic phosphonate compound exhibits good flame retardancy and impact strength, does not release halide gas during preparation or combustion of the resin composition, and thus is environmentally friendly.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: July 17, 2012
    Assignee: Cheil Industries Inc.
    Inventors: Beom Jun Joo, Sang Hyen Hong, Min Soo Lee, Byun Kun Lee
  • Publication number: 20110136993
    Abstract: Phosphorus-containing compounds of formula (I): (I) wherein m, n, R, R1 and R2 are as set forth in the claims. The compounds of formula (I) can be used to provide polymers with flame retardant properties.
    Type: Application
    Filed: August 26, 2009
    Publication date: June 9, 2011
    Applicant: Dow Global Technologies LLC
    Inventors: Anteneh Z Worku, Ashwin R. Bharadwaj, Raymond J. Thibault, Mark B. Wilson, Douglas L. Potts
  • Patent number: 7919481
    Abstract: The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: April 5, 2011
    Assignee: NormOxys, Inc.
    Inventors: Yves Claude Nicolau, Jean-Marie Lehn, Konstantina Fylaktakidou, Ruth Greferath
  • Patent number: 7648970
    Abstract: The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: January 19, 2010
    Assignee: Normoxys, Inc.
    Inventors: Yves Claude Nicolau, Jean-Marie Lehn, Konstantina Fylaktakidou, Ruth Greferath
  • Patent number: 7618954
    Abstract: The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: November 17, 2009
    Assignees: NormOxys, Inc., Universite de Strasbourg
    Inventors: Yves Claude Nicolau, Jean-Marie Lehn, Konstantina Fylaktakidou, Ruth Greferath
  • Publication number: 20090163627
    Abstract: Disclosed herein is a symmetric cyclic phosphonate compound represented by the following Formula 1, a method of preparing the same and a flame retardant styrenic resin composition including the same: wherein R1 and R2 are each independently hydrogen, C1-C6 alkyl or C6-C20 aryl. The styrenic resin composition employing the symmetric cyclic phosphonate compound exhibits good flame retardancy and impact strength, does not release halide gas during preparation or combustion of the resin composition, and thus is environmentally friendly.
    Type: Application
    Filed: December 16, 2008
    Publication date: June 25, 2009
    Applicant: CHEIL INDUSTRIES INC.
    Inventors: Beom Jun JOO, Sang Hyen HONG, Min Soo LEE, Byun Kun LEE
  • Patent number: 7365113
    Abstract: Flavan-based and spirodichroman compound-based phosphate esters prepared by reacting flavans and spirodichroman compounds with phosphorus oxychloride, monophenyl dichlorophosphate, or diphenyl chlorophosphate compounds are described. The flavans and spirodichroman compounds can be synthesized by the reaction of resorcinol with aliphatic acetone. Such phosphate esters can be used as flame retardants.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: April 29, 2008
    Inventors: Raj B. Durairaj, Gary A. Jesionowski
  • Patent number: 7294729
    Abstract: A novel bis-chelating composition characterized by formula I: wherein M is a Group VB element; R1 and R2 are each independently selected from hydrogen and monovalent hydrocarbyl radicals; or R1 and R2 are bonded together to form a diradical; or one of R1 or R2 is hydrogen or a monovalent hydrocarbyl radical, while the other of R1 or R2 is a hydrocarbyl radical bonded to an atom in Ar; wherein Ar is selected from 1,2-arylenes; Q is selected from 1,2-arylenes, 2,2?-bisarylenes and alkyl diradicals; and W is selected from II, III, IV, or V: wherein M is as defined hereinbefore; each R is independently selected from hydrogen and monovalent hydrocarbyl radicals; X is selected from alkyl and aryl diradicals; Ar1 and Ar2 are each independently selected from 1,2-arylenes;Ar3 and Ar4 are each independently selected from monovalent aryl radicals; and n in formula IV is 0 or 1.
    Type: Grant
    Filed: September 26, 2003
    Date of Patent: November 13, 2007
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventors: Wei-Jun Peng, Johnathan E Holladay
  • Patent number: 7279515
    Abstract: Resorcinol carbonate-based phosphate esters are prepared by reacting resorcinol carbonates with phosphorous oxychloride or a chlorophosphate. The resorcinol carbonates can be synthesized by the reaction of resorcinol with phosgene or diphenyl carbonate. The resorcinol carbonate-based phosphate esters can be used as flame retardants and perhaps flowing agents.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: October 9, 2007
    Inventors: Raj B. Durairaj, Gary A. Jesionowski
  • Patent number: 7196230
    Abstract: A novel organophosphorus composition and synthesis thereof, the composition being characterized by one phosphite moiety, one phosoxophite moiety, and a plurality of sterically bulky substituents. The novel composition finds utility as a ligand in Group VIII transition metal phosoxophite complex catalysts and complex catalyst precursors that are used in carbonylation processes, preferably, hydroformylation processes. Additionally, there is disclosed a novel method of preparing a phosphoromonochloridite composition that finds utility as a precursor to the novel phosoxophite composition.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: March 27, 2007
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventors: Wei-Jun Peng, David Robert Bryant
  • Patent number: 7161020
    Abstract: Phosphites of the formula I and phosphite-metal complexes, their preparation and their use in catalytic reactions, in particular in processes for the hydroformylation of olefins, are described.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: January 9, 2007
    Assignee: Oxeno Olefinchemie GmbH
    Inventors: Detlef Selent, Armin Boerner, Cornelia Borgmann, Dieter Hess, Klaus-Diether Wiese
  • Patent number: 7009068
    Abstract: Phosphites of the formula I or II and their metal complexes, their preparation and the use of the phosphites as ligands in catalytic reactions, in particular in processes for the hydroformylation of olefins, are described.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: March 7, 2006
    Assignee: Oxeno Olefinchemie GmbH
    Inventors: Reinhard Schmutzler, Ion Neda, Christine Kunze, Armin Börner, Detlef Selent, Cornelia Borgmann, Dieter Hess, Klaus-Diether Wiese
  • Patent number: 6617028
    Abstract: The present invention discloses a phosphorus- and nitrogen-containing resin hardener, which has a structure represented by the following formula: wherein R2 represents a hydrogen atom or a group represented by the following formula: wherein n is an integer of from 0 to 20, and R represents phenylene, naphthylene or a group represented by the following formula: wherein A represents —O—, —S—, —SO2—, —CO—, —CH2—, —C(CH3)2— or a group represented by the following formula: provided that at least one R2 is not a hydrogen atom; and R1 represents NHR2, C1-6alkyl or phenyl; in the above groups represented by R and A, the aromatic group can be substituted by one or more substituents selected from the group consisting of hydroxy, amino, carboxy and C1-6alkyl. The present invention also discloses a flame retarding composition containing said hardener.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: September 9, 2003
    Assignee: Chang Chun Plastics Co., Ltd.
    Inventors: Kuen Yuan Hwang, Hong Hsing Chen, An Pang Tu
  • Patent number: 6570033
    Abstract: A bisphosphite of the formula I wherein R1, R2, R3 and R4 are each hydrogen, an aliphatic, alicyclic, aliphatic-alicyclic, aromatic, aromatic—aromatic, aliphatic-aromatic hydrocarbon or heterocyclic or aliphatic-heterocyclic group having from 1 to 50 carbon atoms, F, Cl, Br, I, —CF3, —OR7, —COR7, —CO2R7, —CO2M, —SR7, —SO2R7, —SOR7, —SO3R7, —SO3M, —CO2NR7R8, NR7R8, N═CR7R8, NH2, where R1 to R4 are identical or different and may be covalently linked to one another; R7 and R8 are each hydrogen, a substituted or unsubstituted, aliphatic or aromatic hydrocarbon radical having from 1 to 25 carbon atoms, and may be identical or different; M is an alkali metal, alkaline earth metal, ammonium or phosphonium ion; Q is a substituted or unsubstituted divalent aliphatic, alicyclic, aliphatic-alicyclic, aromatic, aliphatic-aromatic hydrocarbon, heterocyclic or aliphatic-heterocyclic radical having from 1 to 50 carbon atoms whe
    Type: Grant
    Filed: October 29, 2001
    Date of Patent: May 27, 2003
    Assignee: Oxeno Olefinchemie GmbH
    Inventors: Dirk Röttger, Dieter Hess, Klaus-Diether Wiese, Cornelia Borgmann, Armin Börner, Detlef Selent, Reinhard Schmutzler, Christine Kunze
  • Publication number: 20020193620
    Abstract: A process to produce organic phosphites from the group consisting of: 1
    Type: Application
    Filed: June 12, 2002
    Publication date: December 19, 2002
    Applicant: General Electric Co.
    Inventor: Gary Vincent Marlin
  • Publication number: 20020161220
    Abstract: Disclosed are novel bicyclic tris(anhydride)s useful as intermediates in the synthesis of biologically active compounds, and the compounds which may be synthesized from such intermediates.
    Type: Application
    Filed: November 13, 2001
    Publication date: October 31, 2002
    Inventors: Krzysztof W. Pankiewicz, Krystyna Lesiak, Kyoichi A. Watanabe
  • Patent number: 6329547
    Abstract: The present invention provides compounds represented by the following general formula [I] and salts thereof, which are useful as therapeutic agents for glaucoma, wherein R1 is H, lower alkyl or phenyl, and the phenyl can be substituted by lower alkyl, hydroxy, lower alkoxy, halogen, nitro or phenyl; R2 and R3, being the same or different, are H, halogen or lower alkyl; R4 and R5, being the same or different, are H, lower alkyl or carboxyl or ester thereof; and R6 is carboxyl or phosphono or ester thereof.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: December 11, 2001
    Assignee: Santen Pharmaceutical Co., Ltd.
    Inventors: Eiichi Shirasawa, Koji Konomi, Masaki Ichikawa, Hiroshi Suhara
  • Patent number: 5844028
    Abstract: Certain (1,3,2-dioxaphosphorinanemethan) amine compounds, which are useful as flame retardant compounds, are disclosed. The compounds are particularly useful in polyurethane compositions.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: December 1, 1998
    Assignee: Solutia Inc.
    Inventor: Frank E. Paulik
  • Patent number: 5726165
    Abstract: A compound of formula (I): ##STR1## or a pharmaceutically acceptable salt, or solvate thereof, wherein,R.sup.o represents an aryl group, optionally substituted;X represents O or S;R.sup.1 and R.sup.1a each independently represents hydrogen or an alkyl group;R.sup.2 represents OCH.sub.2 CO.sub.2 H, or an ester or amide thereof, or R.sup.2 represents a moiety of formula (b): ##STR2## wherein R.sup.4 represent hydrogen, alkyl, hydroxyalkyl, arylalkyl, aralkyloxyalkyl or cycloalkyl and R.sup.5 represent hydroxy, alkoxy, arylalkyloxy, hydroxyalkyloxy, alkoxyalkyloxy, arylalkoxyalkyloxy, cycloalkyloxy, hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, arylalkyl, arylalkyloxyalkyl or R.sup.5 together with OR.sup.4 represents O(CH.sub.2).sub.n O wherein n is 2, 3 or 4; andR.sup.3 represents hydrogen, halogen, alkyl or alkoxy or R.sup.3 together with R.sup.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 10, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Lee James Beeley, Mervyn Thompson, David Kenneth Dean, Nikesh Rasiklal Kotecha, John Michael Berge, Robert William Ward
  • Patent number: 5717126
    Abstract: Phosphorus-containing calixarenes of the general formula I ##STR1## and a process for their preparation are described. Additionally, a process for the preparation of aldehydes by the hydroformylation of C.sub.3 -C.sub.20 -olefins by means of rhodium or ruthenium carbonyl complexes, in which the phosphorus-containing calixarenes of the formula I are used as ligands, is described.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: February 10, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Rocco Paciello, Michael Roper, Heinz-Josef Kneuper, Ernst Langguth, Peter Michael Lorz
  • Patent number: 5710305
    Abstract: A method for producing alkyl derivatives of phosphonic acids together with hexyl-bis?5-ethyl-2-hexyl-1,3,2-dioxaphosphorinan-5-yl)methyl!ester, P,P'dioxide as a novel product and the use of such a product as, or in connection with, a flame retardant.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: January 20, 1998
    Assignee: Albright & Wilson UK Limited
    Inventors: Adrian Charles Archer, Christopher John Harris, Gary Woodward, Mohsen Zakikhani
  • Patent number: 5705668
    Abstract: New phosphazene derivatives, fully substituted by aromatic groups and perfluoropolyethereal chains, are utilized as stabilizers for oils and greases based on perfluoropolyethers. Such derivatives inhibit the degradation process affecting the perfluoropolyethereal chains when these are subjected to high temperatures in an oxidizing atmosphere and in the presence of metals, such as for example aluminium, titanium, vanadium and their alloys, or steels.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: January 6, 1998
    Assignee: Ausimont S.p.A.
    Inventors: Paolo Odello, Walter Navarrini, Richard Dickinson Chambers, Costante Corti
  • Patent number: 5688847
    Abstract: Disclosed is a fluorophosphite compound of the formula ##STR1## This compound shows superior performance as a stabilizer in polymers, such as polypropylene, and polyvinyl chloride. Also disclosed is a process for making this compound.
    Type: Grant
    Filed: November 7, 1996
    Date of Patent: November 18, 1997
    Assignee: Witco Corporation
    Inventors: Michael E. Gelbin, Michael H. Fisch, R. David Peveler
  • Patent number: 5502231
    Abstract: The present invention relates to a process for the preparation of compounds of the general formula I ##STR1## in which R.sup.1 and R.sup.2 are defined as stated in claim 1, characterized in that a 1,1,1-tris(hydroxymethyl)-(C.sub.2 -C.sub.5)-alkane or 2,2-bis(hydroxymethyl)-1,3-propanediol is reacted with vinylphosphonic anhydride.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: March 26, 1996
    Assignee: Cassella Aktiengesellschaft
    Inventors: Fritz Engelhardt, Ulrich Riegel, Hans-Jerg Kleiner
  • Patent number: 5347029
    Abstract: Provided are novel dialkyl (dialkoxyphosphinyl)methyl phosphates of formula ##STR1## which am useful as anti-inflammatory and anti-arthritic agents. The compounds are synthesized from the reaction of tetraethyl oxiranylidenebisphosphonate and unsubstituted or alkyl-amines. Representative compounds include 2-(benzylamino)-1-(diethoxyphosphinyl)ethyl phosphonic acid diethyl ester, 1-(diethoxyphosphinyl)-2-[2'-(1', 2', 3', 4'-tetrahydro)napthylamino]ethyl phosphonic acid diethyl ester, 2-(3-fluorobenzylamino)-1-(diethoxyphosphinyl)ethyl phosphonic acid diethyl ester, and 5,5 -dimethyl-2-[2-(3-fluorobenzyl)amino-1-[(5,5-dimethyl-1,3,2-dioxaphosphori nan-2-yl)oxy]ethyl]-1,3,2-dioxaphosphorinane P,2-dioxide.
    Type: Grant
    Filed: December 16, 1993
    Date of Patent: September 13, 1994
    Assignee: The Upjohn Company
    Inventor: Roy A. Johnson
  • Patent number: 5342869
    Abstract: A composition, having good weatherability properties, comprisinga) one or more compounds of formula I ##STR1## in which m is 1;n is 0 or 1;p is 0;each R or R.sup.1 independently, is a group derived from an aliphatic, alicyclic or aromatic alcohol containing one or two OH groups; whereby the two --OH groups are not positioned to be able to form a P-containing ring;or both groups R form a group derived from an aliphatic, alicyclic or aromatic alcohol containing two OH groups in such a position that they can form a cyclic group with a single phosphorus atom;Y is --O--, --S--, --CH(R.sub.5)-- or --C.sub.6 H.sub.4 --;where R.sub.5 is hydrogen or C.sub.1-8 alkyl or COOR.sub.6 and R.sub.6 is C.sub.1-8 alkyl; andb) a polymeric material.
    Type: Grant
    Filed: July 6, 1992
    Date of Patent: August 30, 1994
    Assignee: Sandoz Ltd.
    Inventors: Klaus Stoll, Rainer Wolf
  • Patent number: 5308902
    Abstract: Biphosphites of formula I ##STR1## wherein m is 0, 1 or 2,n is 1 to 4 or 6,R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl and, if m=2, the radicals R.sub.1 are identical or different, and A is the radical of an at least n-hydric alcohol or phenol, which radical is attached to the P atom or atoms through the alcoholic or phenolic O atom or atoms, obtainable by reacting a compound of formula II ##STR2## wherein m is 0, 1 or 2, R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl and, if m=2, the radicals R.sub.1 are identical or different and R.sub.2 ' is phenyl, C.sub.1 -C.sub.12 alkylphenyl or C.sub.1 -C.sub.4 alkyl, with a polyether polyol or polyether/ester polyol, the hydroxy functions of said polyether polyol or polyether/ester polyol being partially or completely esterified with the ##STR3## are suitable for use as stabilizers, especially processing stabilizers, for organic polymers, preferably PVC resins, high density polyethylene and propylene.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: May 3, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Holger Andreas, Alfred Renner, Horst Zinke
  • Patent number: 5288869
    Abstract: A new group of pentaerythryl diphosphonates and poly(pentaerythryl diphosphonates) are described. Flame-retardant compositions are also described, which include a thermoplastic polymer and a certain amount of self-extinguishing agent consisting of one of the above-mentioned pentaerythryl diphosphonates or poly(pentaerythryl diphosphonates).
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: February 22, 1994
    Assignee: Enichem Synthesis S.p.A.
    Inventors: William Giroldini, Gianluigi Landoni, Antonio Rinaldi, Carlo Neri
  • Patent number: 5254276
    Abstract: Cyclic diol- and diol-ester phosphite adducts of olefins and polymeric olefins provide superior multifunctional and lubricating fluid media with internal synergistic multifunctional antiwear, antioxidant properties and extreme pressure/antiwear additives for both mineral and synthetic lubricating oils as well as liquid hydrocarbon fuels.
    Type: Grant
    Filed: February 3, 1992
    Date of Patent: October 19, 1993
    Assignee: Mobil Oil Corporation
    Inventors: Linda A. Benjamin, Andrew G. Horodysky, Derek A. Law, Shi-Ming Wu
  • Patent number: 5239103
    Abstract: 3,7,9-Trioxa-1-aza-2,8-diphosphaspiro[4.5]decanes of formula I ##STR1## wherein R.sub.1 and R.sub.2 are independently hydrogen, alkyl, cycloalkyl, bicycloalkyl, tricycloalkyl or aryl; or can be halogen when n or m is zero,R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are independently hydrogen, alkyl, aralkyl or aryl;X and Y are independently --O--, --S-- or --NR.sub.16 -- where R.sub.16 is alkyl, cycloalkyl, alkenyl, aryl or aralkyl;W and Z are independently O or S; andn, m, o and p are independently zero or 1, are effective in stabilizing organic materials against the deleterious effects of oxygen, heat and/or actinic radiation.
    Type: Grant
    Filed: November 12, 1992
    Date of Patent: August 24, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Raymond Seltzer, Paul A. Odorisio, Sai P. Shum, Stephen D. Pastor
  • Patent number: 5177237
    Abstract: A hydrazine derivative having the formula: ##STR1## wherein R is a hydrogen atom or ##STR2##
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: January 5, 1993
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Hiroo Matsumoto, Kiyotomo Seto, Ryozo Sakoda
  • Patent number: 5157027
    Abstract: Compounds which are inhibitors of cholesterol biosynthesis (by inhibiting de novo squalene biosynthesis), and thus are useful as hypocholesterolemic agents and antiatherosclerotic agents are provided which have the structure ##STR1## and analogs thereof, wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same or different and are H, lower alkyl, a metal ion or a prodrug ester;R.sup.5 is H, halogen or lower alkyl;Zq is substituted alkenyl, substituted alkynyl, mixed alkenyl-alkynyl or substituted phenylalkyl or, phenylalkenyl or phenylalkynyl, or alkyl, including all stereoisomers thereof.New methods for using such compounds to inhibit cholesterol biosynthesis are also provided.
    Type: Grant
    Filed: May 13, 1991
    Date of Patent: October 20, 1992
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Scott A. Biller, David R. Magnin
  • Patent number: 5075482
    Abstract: 3,7,9-Trioxa-1-aza-2,8-diphosphaspiro[4.5]decanes of formula I ##STR1## wherein R.sub.1 and R.sub.2 are independently hydrogen, alkyl, cycloalkyl, bicycloalkyl, tricycloalkyl or aryl; or can be halogen when n or m is zero,R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are independently hydrogen, alkyl, aralkyl or aryl;X and Y are independently --O-- --S--, or --NR.sub.16 -- where R.sub.16 is alkyl, cycloalkyl, alkenyl, aryl or aralkyl;W and Z are independently O or S; andn, m, o and p are independently zero or 1, are effective in stabilizing organic materials against the deleterious effects of oxygen, heat and/or actinic radiation.
    Type: Grant
    Filed: August 23, 1990
    Date of Patent: December 24, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Raymond Seltzer, Paul A. Odorisio, Sai P. Shum, Stephen D. Pastor
  • Patent number: 5070082
    Abstract: The N-phosphorylation of basic nitrogenous drug compounds to produce pro-drugs with enhanced water solubility or lipid solubility, or reduced toxicity, is disclosed. Drugs containing amine, amidine, guadinine, isourea, isothiourea an biguanide functions may be converted to such pro-drugs. The pro-drugs are hydrolyzed in the body, regenerating the original drugs with the release of a salt of phsophoric acid.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: December 3, 1991
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Ving J. Lee
  • Patent number: 5043330
    Abstract: The invention relates to new gem-diphosphonates derivatives substituted by phenol groups of formula (I): ##STR1## as well as the process for their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 14, 1989
    Date of Patent: August 27, 1991
    Assignee: Symphar S.A.
    Inventors: Lan Nguyen, Eric Niesor, Hieu Phan, Pierre Maechler, Craig Bentzen
  • Patent number: 4758683
    Abstract: A spirodiphosphoamidate-type composition is provided, wherein the composition is represented by the general formula: ##STR1## wherein A and A' are independently selected from the group consisting of oxygen and sulfur; R.sup.1 and R.sup.3 are independently selected from the group consisting of hydrogen, aliphatic, oxyaliphatic, polyoxyaliphatic, cycloaliphatic and aromatic moieties; and R.sup.2 and R.sup.4 are independently selected from the group consisting of C.sub.13 and larger aliphatic, oxyaliphatic, polyoxyaliphatic and aliphatic substituted aryl groups.
    Type: Grant
    Filed: September 25, 1987
    Date of Patent: July 19, 1988
    Assignee: Borg-Warner Chemicals, Inc.
    Inventors: Lee Cherney, Yuval Halpern
  • Patent number: 4670492
    Abstract: Cyclic bis and tris phosphites are provided having the formula: ##STR1## wherein: A is selected from the group consisting of sulfur; oxygen; alkylidene having from one to about six carbon atoms; cycloalkylidene having from three to about eight carbon atoms; and phenyl and alkyl phenyl alkylidene having from seven to about fourteen carbon atoms;R is selected from the group consisting of alkyl having from one to about eighteen carbon atoms; cycloalkyl having from three to about eight carbon atoms; and phenalkylidene and alkyl phenalkylidene having from seven to about twelve carbon atoms;R.sub.1 is selected from the group consisting of hydrogen; alkyl having from one to about eighteen carbon atoms; cycloalkyl having from three to about eight carbon atoms; and phenalkylidene and alkyl phenalkylidene having from seven to about twelve carbon atoms;n is 2 or 3;R.sub.2 is ##STR2## wherein: m=0 when n is 2; and 1 when n is 3;R.sub.3, R.sub.4, R.sub.5, R.sub.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: June 2, 1987
    Assignee: Adeka Argus Chemical Co., Ltd.
    Inventors: Yutaka Nakahara, Tohru Haruna, Etsuo Tobita
  • Patent number: 4650609
    Abstract: Compounds having a quinodimethane or a 7,8-dihydroquinodimethane nucleus and four substituted phosphinyl groups at the 7- and 8-positions are disclosed. A process for preparing the specified compounds is also disclosed.
    Type: Grant
    Filed: June 25, 1985
    Date of Patent: March 17, 1987
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: David R. Brittelli