Halogen In Acid Moiety Patents (Class 560/219)
  • Patent number: 4153804
    Abstract: A fluorinated vinyl ether having an ester group which has the formulaCF.sub.2 .dbd. CFOCF.sub.2 (CF(CF.sub.3)OCF.sub.2).sub.n-1 (Rf).sub.m CO.sub.2 Rwherein n represents an integer of 1 to 5; m represents 0 or 1; Rf represents a C.sub.1 -C.sub.10 bifunctional perfluoro group and R represents an alkyl group, is produced by reacting fluorinated acyl fluoride having an ester group which has the formulaFOC(CF(CF.sub.3)OCF.sub.2).sub.n (Rf).sub.m CO.sub.2 Rwith an alkali metal carbonate to produce an alkali metal salt of fluorinated carboxylic acid having an ester group which has the formulaMOOC(CF(CF.sub.3)OCF.sub.2).sub.n (Rf).sub.m CO.sub.2 Rwherein M represnts an alkali metal;And then, thermally decomposing the alkali metal salt of fluorinated carboxylic acid having an ester group.
    Type: Grant
    Filed: June 21, 1978
    Date of Patent: May 8, 1979
    Assignee: Asahi Glass Co. Ltd.
    Inventors: Masaaki Yamabe, Seiji Munekata, Shunichi Samejima
  • Patent number: 4103025
    Abstract: Pharmaceutically active compounds of the formula ##STR1## wherein --OR.sub.1, --OR.sub.2, --OR.sub.3 and --OR.sub.4, which may be the same or different, each represents a free or esterified hydroxyl group and --COOR.sub.5 represents a free or esterified carboxyl group, are provided together with processes for their production and pharmaceutical compositions containing them. Compounds of formula II and III possess valuable cicatrizing and anti-inflammatory properties.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: July 25, 1978
    Assignee: Inverni Della Beffa S.p.A.
    Inventor: Giuseppe Mustich
  • Patent number: 4098805
    Abstract: The present invention relates in part to novel amido, cycloamido, carbonylamido and sulfonylamido derivatives and p-substituted phenyl esters of 9-deoxy-9-methylene-PGF-type compounds. These novel amides produce surprisingly prolonged oral activity as pharmacological agents, as compared to the previously known 9-deoxy-9-methylene-PGF-type compounds.Further, the novel p-substituted phenyl esters provide more stable pharmaceutical formulations as compared to known 9-deoxy-9-methylene-PGF-type esters.Additionally, a novel series of 16-phenyl-9-deoxy-9-methylene-PGF-type compounds in free acid, ester, C-1 alcohol, and C-1 amine form is provided. Such compounds exhibit characteristic prostaglandin-type pharmacological actions.
    Type: Grant
    Filed: April 11, 1977
    Date of Patent: July 4, 1978
    Assignee: The Upjohn Company
    Inventor: Gordon L. Bundy
  • Patent number: 4092337
    Abstract: New bromine compounds are provided. They correspond to the formulaH -- X' -- COO -- (X--OOC).sub.t-1 -- X" -- Hin which t is 1 or 2 and X, X' and X" are brominated alkylene. The new compounds are useful as flameproofing agents for synthetic fibers.
    Type: Grant
    Filed: June 30, 1976
    Date of Patent: May 30, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: Horst Jager, Peter Rohringer
  • Patent number: 4083855
    Abstract: A method for producing a 3,3-dimethyl-4-(2,2-dihalogenovinyl)-4-hydroxybutyric-1,4-lactone of the formula, ##STR1## wherein X is a halogen atom, which comprises reacting a 1,1,1-trihalogeno-4-methyl-3-pentene-2-ol of the formula, ##STR2## wherein X is a halogen atom, or a 1,1,1-trihalogeno-4-methyl-4-pentene-2-ol of the formula, ##STR3## wherein X is a halogen atom, or the mixture of the both compounds with vinylidene chloride of the formula, ##STR4## IN SULFURIC ACID.
    Type: Grant
    Filed: February 4, 1977
    Date of Patent: April 11, 1978
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Nobushige Itaya, Fumio Fujita
  • Patent number: 4061867
    Abstract: Immobilized enzymes, intermediates therefor, and a process for the preparation of such substances are described. The method comprises reacting an enzyme with a polymerizable, ethylenically, unsaturated monomer containing a reactive group, and then polymerizing or copolymerizing the covalently-bonded enzyme-monomer product thus produced in the presence of a cross-linking agent and an initiator. The process affords immobilized enzymes of high stability and activity.
    Type: Grant
    Filed: August 13, 1975
    Date of Patent: December 6, 1977
    Assignee: Caterpillar Tractor Co.
    Inventor: James J. Hamsher