Halogen In Acid Moiety Patents (Class 560/62)
-
Patent number: 4699920Abstract: The invention relates to 9-halo-.DELTA..sup.2 -prostane derivatives of general Formula I ##STR1## wherein Hal is a fluorine or chlorine atom in the .alpha.- or .beta.-position,R.sub.1 is the residue OR.sub.2 with R.sub.2 meaning a hydrogen atom, alkyl, cycloalkyl, aryl or a heterocyclic residue; or the residue NHR.sub.3 wherein R.sub.3 means an acid residue or the residue R.sub.2 andA is a --CH.sub.2 --CH.sub.2 -- or cis-CH.dbd.CH--group,B is a --CH.sub.2 --CH.sub.2 -- or trans--CH.dbd.CH-- or --C.tbd.C--group,W is a free or functionally modified hydroxymethylene or ##STR2## wherein the respective OH-groups can be in the .alpha.- or .beta.-position,D and E jointly mean a direct bond orD is a straight- or branched-chain alkylene group of 1-10 carbon atoms, which can optionally be substituted by fluorine atoms,E is an oxygen or sulfur atom, a direct bond, a --C.tbd.C--bond or a --CR.sub.6 .dbd.CR.sub.7 --group wherein R.sub.6 is a hydrogen atom or an alkyl group and R.sub.Type: GrantFiled: September 17, 1985Date of Patent: October 13, 1987Assignee: Schering AktiengesellschaftInventors: Werner Skuballa, Bernd Raduchel, Helmut Vorbruggen, Walter Elger, Olaf Loge
-
Patent number: 4683327Abstract: A novel heat-curable acrylic-terminated monomer is provided which exhibits an optically anisotropic melt phase at a temperature which enables it to undergo melt processing in the formation of molded articles, etc. Subsequent to melt processing articles prepared from the monomer are capable of being cured to produce a thermoset self-reinforced composite which is soft and flexible relative to prior art monomers. The monomer may, for example, consist essentially of the reaction product of a methacrylic-substituted phenol and terephthalic acid.Type: GrantFiled: June 24, 1985Date of Patent: July 28, 1987Assignee: Celanese CorporationInventor: Robert W. Stackman
-
Patent number: 4681941Abstract: An improved method of preparing aryloxyphenoxy propanoic acid esters is disclosed. Low-water levels and low temperatures increase the yield and decrease by-product formation. A hindered non-nucleophilic phenol, which is converted in situ to the phenate form, is added to the reaction mixture to drive the reaction to 99+% conversion.Type: GrantFiled: April 11, 1985Date of Patent: July 21, 1987Assignee: The Dow Chemical CompanyInventor: Timothy J. Adaway
-
Patent number: 4673529Abstract: A novel liquid crystal compound useful as a component of liquid crystal compositions and a liquid crystal composition containing the same are provided, which compound is a phenoxypropanol ester derivative expressed by the formula ##STR1## wherein R.sup.1 and R.sup.2 each represent an alkyl group or an alkoxy group each of 1 to 15 carbon atoms, F atom, Cl atom or CN group, but either one of R.sup.1 and R.sup.Type: GrantFiled: November 27, 1985Date of Patent: June 16, 1987Assignee: Chisso CorporationInventors: Shigeru Sugimori, Tetsuya Ogawa, Yasuyuki Goto, Toyoshiro Isoyama, Kazunori Nigorikawa, Kisei Kitano, Naoyuki Yoshida, Yoshito Furukawa
-
Patent number: 4661618Abstract: This invention relates to the new 1,3-bis-(dimethylamino)-2-propyl-4-chlorophenoxyacetate of the Formula (I) ##STR1## acid addition salts thereof, a process for the preparation of the same and pharmaceutical compositions comprising the said compounds.The novel compound of the present invention corresponds to the Formula (I). This compound stimulates the function of the brain cells and thereby mental activity.The compound of the Formula (I) can be prepared by esterifying (4-chlorophenoxy)-acetic acid or a functional reactive derivative thereof with 1,3-bis-(dimethylamino)-2-propanol or a halogeno derivative thereof in a manner known per se.Type: GrantFiled: May 2, 1984Date of Patent: April 28, 1987Assignee: Biogal GyogyszergyarInventors: Imre Z. Nagy, Zsuzsanna Emri, Sandor Jancso, Istvan Csernus, Janos Balint
-
Patent number: 4659370Abstract: Novel substituted phenoxypropionates of the formula ##STR1## in which Ar represents the group ##STR2## or the group ##STR3## in which Y represents a halogen atom or a trifluoromethyl group andb is 1 or 2,R represents a hydrogen atom or a methyl group,X represents a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group or a lower alkoxy group,a and m each independently is 1 or 2, andn is 0, 1 or 2,and their use as herbicides.Novel intermediates of the formulae ##STR4## in which formulae R, X, m, n and a have the meanings given above,Z.sup.1 is a halogen atom andm is a hydrogen atom or an alkali metal atom.Type: GrantFiled: May 22, 1984Date of Patent: April 21, 1987Assignee: Nihon Tokushu Noyaku Seizo K.K.Inventors: Junichi Saito, Kazuomi Yasui, Kozo Shiokawa, Atsumi Kamochi
-
Patent number: 4639537Abstract: New laevorotatory enantiomers of phenoxy propionic acid derivatives of the formula ##STR1## in which R.sup.2 represents a radical of the formula ##STR2## wherein Y represents oxygen or the radical SO.sub.m,whereinm represents 0, 1 or 2,R.sup.2 represents hydrogen or methyl,n represents 1 or 2 andR.sup.3 and R.sup.4 independently of one another represent hydrogen, halogen, alkyl with 1 to 4 carbon atoms, alkoxy with 1 to 4 carbon atoms, alkylthio with 1 to 4 carbon atoms, nitro, cyano or alkoxycarbonyl with 1 to 4 carbon atoms in the alkoxy group, and their use as intermediates for preparing herbicides.Type: GrantFiled: May 24, 1985Date of Patent: January 27, 1987Assignee: Bayer AktiengesellschaftInventors: Koichi Moriya, Uwe Priesnitz, Hans-Jochem Riebel, Ludwig Eue, Robert R. Schmidt
-
Patent number: 4638082Abstract: A novel method of producing the p-chlorophenol ester of p-chlorophenoxyisobutyric acid, which is a product useful in the treatment of hyperlipemias, is disclosed.Type: GrantFiled: February 25, 1986Date of Patent: January 20, 1987Assignee: Societe Corial, S.A.Inventors: Claude Feniou, Patrick Descas
-
Patent number: 4627933Abstract: Compounds of the formulaR.sup.1 --Q.sup.1 --(CH.sub.2).sub.m --(COO).sub.n --(CH.sub.2).sub.p --Q.sup.2 --R.sup.2whereinR.sup.1 and R.sup.2 are each independently alkyl or alkoxy each of 1-12 C atoms, F, Cl, Br, CN or --Q.sup.3 --R.sup.3, or one of R.sup.1 and R.sup.2 can also be H;Q.sup.1, Q.sup.2 and Q.sup.3 are each independently 1,4-phenylene, 1,4-cyclohexylene, 1,4-bicyclo(2,2,2)-octylene or 1,3-dioxane-2,5-diyl, each of which is unsubstituted or substituted by 1-4 fluorine, chlorine or bromine atoms;R.sup.3 is alkyl or alkoxy each of 1-8 C atoms, H, F, Cl, Br or CN;m is 1, 2, 3, 4, 5 or 6; n is 0 or 1; and p is 0, 1, 2, 3, 4 or 5; the sum of (m+p) being 2, 4 or 6 and the sum of (m+n+p) being at least 3;but with the proviso that Q.sup.3 is unsubstituted 1,4-phenylene or 1,4-phenylene substituted by a fluorine, chlorine or bromine atom, only when n=1 or (m+p)=6 or at least one of R.sup.1 or R.sup.3 is F, Cl or Br or none of R.sup.1 to R.sup.3 is CN or two of the radicals R.sup.1 to R.sup.Type: GrantFiled: July 7, 1983Date of Patent: December 9, 1986Assignees: Merck Patent Gesellschaft mit beschrankter Haftung, The Secretary of State for Defense in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern IrelandInventors: Rudolf Eidenschink, Joachim Krause, Beatrice M. Andrews, George W. Gray, Neil Carr
-
Patent number: 4622415Abstract: There is disclosed an R enantiomer of phenoxypropionic acid compound of the formula ##STR1## in which X represents hydrogen or halogen, and R represents hydroxyl, alkoxy, halogen or the radical of the formula ##STR2## wherein R.sup.1 and R.sup.2 independently of one another represent hydrogen or methyl, n represents 0, 1 or 2 and Y represents trimethylsilyl, or optionally substituted azolyl bonded via nitrogen, or represents alkoxy, alkoxycarbonyl or the radical of the formula ##STR3## wherein Q represents oxygen, sulphur, SO or SO.sub.2 and R.sup.3 and R.sup.4 independently of one another represent hydrogen, halogen, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, alkylthio having 1 to 4 carbon atoms, nitro, cyano or alkoxycarbonyl having 1 to 4 carbon atoms in the alkoxy group; compositions containing herbicidally effective amounts of such R enantiomers and the use of such R enantiomers as herbicides.Type: GrantFiled: July 31, 1985Date of Patent: November 11, 1986Assignee: Bayer AktiengesellschaftInventors: Heinz Forster, Bernd Gallenkamp, Uwe Priesnitz, Hans-Jochem Riebel, Ludwig Eue, Robert R. Schmidt
-
Patent number: 4614608Abstract: The invention relates to a group of organic compounds of the 1-(4-hydroxyphenyl)-2-(4'-trifluoromethylphenyl)-ethane ester type having a mesomorphous phase of the smectic A type, to the mixtures obtained from said compounds, as well as to the process for producing the molecules of said group. The compound according to the invention is in accordance with the general chemical formula: ##STR1## whereby n can be between 1 and 15.Type: GrantFiled: March 13, 1985Date of Patent: September 30, 1986Assignee: Thomson-CSFInventors: Pierre Le Barny, Jean C. Dubois, Gilles Ravaux
-
Patent number: 4607116Abstract: Provided is a process for preparing a diaryl or a mixture of diaryls represented by any or a combination of the following formulae (II), (III) and (V), characterized in that a diaryliodonium salt represented by the following formula (I) is reacted in a solvent in the presence of a transition metal catalyst and a reducing metal at a temperature in the range of room temperature to 100.degree. C.:[Ar.sub.1 -I.sup..sym. -Ar.sub.2 ]X.sup..crclbar. (I)Ar.sub.1 -Ar.sub.1 (II)Ar.sub.1 -Ar.sub.2 (III)Ar.sub.2 -Ar.sub.2 (IV)wherein Ar.sub.1 and Ar.sub.2, which may be alike or different, are each an aryl group which may have a substituent group or groups and X.sup..crclbar. is a counter ion which is inert to said reaction.Type: GrantFiled: March 8, 1984Date of Patent: August 19, 1986Assignee: Nippon Petrochemicals Company LimitedInventors: Yasuo Yamazaki, Takehiko Suzuki, Masaharu Uchiyama
-
Patent number: 4598085Abstract: Novel compounds of the class of 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles having fungicidal and plant-growth regulating properties.Type: GrantFiled: January 21, 1982Date of Patent: July 1, 1986Assignee: Janssen Pharmaceutica N.V.Inventors: Jan Heeres, Leo J. J. Backx, Joseph A. Mostmans
-
Patent number: 4596599Abstract: New dextrorotatory enantiomers of phenoxy propionic acid derivatives of the formula ##STR1## in which R.sup.1 represents a radical of the formula ##STR2## wherein X.sup.1 represents hydrogen or halogen,X.sup.2 represents halogen or trifluoromethyl,X.sup.3 represents halogen or trifluoromethyl,X.sup.4 represents hydrogen or halogen andX.sup.5 represents hydrogen or halogen,Y represents oxygen or the radical SO.sub.m,whereinm represents 0, 1 or 2,R.sup.2 represents hydrogen or methyl,n represents 1 or 2 andR.sup.3 and R.sup.4 independently of one another represent hydrogen, halogen, alkyl with 1 to 4 carbon atoms, alkoxy with 1 to 4 carbon atoms, alkylthio with 1 to 4 carbon atoms, nitro, cyano or alkoxycarbonyl with 1 to 4 carbon atoms in the alkoxy group, and their use as herbicides.Type: GrantFiled: December 12, 1983Date of Patent: June 24, 1986Assignee: Bayer AktiengesellschaftInventors: Koichi Moriya, Uwe Priesnitz, Hans-Jochem Riebel, Ludwig Eue, Robert R. Schmidt
-
Patent number: 4589907Abstract: Compounds having the formula ##STR1## in which Z is ##STR2## wherein X is hydrogen or halogen and Y is --CH or N; R is alkyl, phenyl, trihalomethylphenyl, cyanomethyl, carboalkoxymethyl, ##STR3## alkenyl; and R.sub.1 is hydrogen, lower alkyl, halo-(lower alkyl), or Z; and intermediate alkyl onium salts of the type ##STR4## in which R.sub.3 is C.sub.1 -C.sub.8 alkyl, G is nitrogen or phosphorus and Z' is ##STR5## wherein X is hydrogen or halogen and Y is --CH or N; are herbicides.Type: GrantFiled: September 17, 1985Date of Patent: May 20, 1986Assignee: Stauffer Chemical CompanyInventor: Raymond A. Felix
-
Patent number: 4552977Abstract: Process for the preparation of (phenoxy- or benzyl-)-phenoxypropionic acids and the alkali metal salts thereof by adding a double molar amount of an aqueous alkali hydroxide to a boiling mixture of a (benzyl- or phenoxy-)-phenol and 2-chloropropionic acid (ester), with simultaneous azeotropic distillation of the water introduced or formed in the reaction.Type: GrantFiled: September 24, 1982Date of Patent: November 12, 1985Assignee: Hoechst AktiengesellschaftInventors: Manfred Koch, Peter Herbrechtsmeier
-
Patent number: 4551264Abstract: New polyhalogenoaromatic compounds of Formula I ##STR1## wherein Y and Z are each independently alkyl, alkoxy or alkanoyl each of 1 to 12 C atoms, --COOR.sup.1, --O--CO--R.sup.1, CN, NO.sub.2, NH.sub.2 or OH;Q is one or two identical or different radicals selected from Ph, Cy, 1,4-bicyclo[2,2,2]octylene or 1,3-dioxane-2,5-diyl;X.sup.1 to X.sup.4 are each independently H, F, Cl or Br;R.sup.1 is alkyl of 1 to 4 C atoms, Ph--R.sup.2 or Cy--R.sup.2 ;R.sup.2 is alkyl or alkoxy each of 1-12 C atoms or CN;Ph is 1,4-phenylene; and Cy is 1,4-cyclohexylene,can be used as components of liquid-crystal dielectrics.Type: GrantFiled: March 14, 1983Date of Patent: November 5, 1985Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Rudolf Eidenschink, Michael Romer, Georg Weber
-
Patent number: 4550981Abstract: Compounds of the formula ##STR1## wherein X.sup.2 is a single covalent bond or --COO--; X.sup.1 is a single covalent bond, --COO--, --CH.sub.2 CH.sub.2 -- or when X.sup.2 is --COO--, X.sup.1 also can be p--C.sub.6 H.sub.4 --, p--C.sub.6 H.sub.4 --CH.sub.2 CH.sub.2 --, --CH.sub.2 CH.sub.2 --p--C.sub.6 H.sub.4, p--C.sub.6 H.sub.4 --COO-- or --COO--p--C.sub.6 H.sub.4 ; ring A is a benzene ring or trans-1,4-cyclohexylene; ring B is a benzene ring or when X.sup.2 is --COO-- and X.sup.1 is a single covalent bond, --COO-- or --CH.sub.2 CH.sub.2 --, ring B also can be trans-1,4-cyclohexylene; Z.sup.1, Z.sup.2 and Z.sup.3 individually are hydrogen or when positioned on a benzene ring which is not linked directly with a further ring via a single covalent bond, Z.sup.1, Z.sup.2 and Z.sup.3 also can be halogen, cyano or methyl; Y.sup.2 is cyano, nitro, 2,2-dicyanovinyl or when Y.sup.1 is hydrogen Y.sup.2 also can be 2,2-dicyano-1-methylvinyl; Y.sup.1 is halogen, cyano, C.sub.1 -C.sub.3 -alkyl or, when X.sup.Type: GrantFiled: September 9, 1983Date of Patent: November 5, 1985Assignee: Hoffmann-La Roche Inc.Inventors: Martin Petrzilka, Martin Schadt, Alois Villiger
-
Patent number: 4550192Abstract: Novel fluorophenoxyphenoxypropionates and derivatives thereof possess herbicidal activity selectively in the presence of broadleaf crops. Preemergent and postemergent applications are contemplated.Type: GrantFiled: September 1, 1983Date of Patent: October 29, 1985Assignee: The Dow Chemical CompanyInventors: Richard B. Rogers, B. Clifford Gerwick, III
-
Patent number: 4531969Abstract: Optically active enantiomers of the formula I ##STR1## where R is a group of the formulae ##STR2## R.sub.1 and R.sub.2, among others, are halogen or CF.sub.3 and Z is a carboxyl, carboxylate, carboxylic acid ester, thioester, carbonamide, carboxylic acid anilide, carbohydrazide or thioamide group, are interesting herbicides the effect of which is considerably superior to that of the optically inactive racemates.Type: GrantFiled: December 20, 1978Date of Patent: July 30, 1985Assignee: Hoechst AktiengesellschaftInventors: Hans J. Nestler, Gerhard Horlein, Reinhard Handte, Hermann Bieringer, Friedhelm Schwerdtle, Peter Langeluddeke
-
Patent number: 4532328Abstract: Process for making optically active esters having an enhanced optical purity by reacting a mole of an appropriate substrate phenol with a molar excess of an appropriate optically active ester.Type: GrantFiled: July 14, 1983Date of Patent: July 30, 1985Assignee: The Dow Chemical CompanyInventor: William A. Kleschick
-
Patent number: 4526704Abstract: Compounds of the formula ##STR1## wherein n is 0 or 1; one of X.sup.1 and X.sup.2 is --COO-- or --OOC-- and the other is a single covalent bond or --CH.sub.2 CH.sub.2 --; X.sup.3 and X.sup.4 individually are a single covalent bond or --CH.sub.2 CH.sub.2 --, with the proviso that at most one of X.sup.1, X.sup.2, X.sup.3 and X.sup.4 is --CH.sub.2 CH.sub.2 --; rings A.sup.1 and A.sup.5 individually are a group of the formula ##STR2## or trans-1,4-cyclohexylene; rings A.sup.2, A.sup.3 and A.sup.4 individually are a group of formula II or, when ring A.sup.2, A.sup.3 or A.sup.4 is not linked with at least one of the other two of these rings by a single covalent bond then such ring also can be trans-1,4-cyclohexylene, with the proviso that at least one of rings A.sup.1 through A.sup.5 is a group of formula II; Y is hydrogen, or when Y is attached to a ring of formula II which is not linked with another ring via a single covalent bond, Y also can be fluorine, chlorine or methyl; and R.sup.1 and R.sup.Type: GrantFiled: July 11, 1983Date of Patent: July 2, 1985Assignee: Hoffmann-La Roche Inc.Inventors: Martin Petrzilka, Martin Schadt, Alois Villiger
-
Patent number: 4522647Abstract: Substituted phenoxyalkanediones and intermediates therefor, and the use of said compounds for the control of weeds.Type: GrantFiled: June 29, 1983Date of Patent: June 11, 1985Assignee: Zoecon CorporationInventors: Richard J. Anderson, Shy-Fuh Lee
-
Patent number: 4520199Abstract: 3-Alkoxy-4-substituted phenoxy alkanoic acid esters, derivatives thereof, and the use thereof for the control of weeds.Type: GrantFiled: August 13, 1982Date of Patent: May 28, 1985Assignee: Zoecon CorporationInventors: Gustave K. Kohn, Joe T. Bamberg
-
Patent number: 4500346Abstract: Novel substituted phenoxypropionates of the formula ##STR1## in which Ar represents the group ##STR2## or the group ##STR3## in which Y represents a halogen atom or a trifluoromethyl group andb is 1 or 2,R represents a hydrogen atom or a methyl group,X represents a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group or a lower alkoxy group,a and m each independently is 1 or 2, andn is 0, 1 or 2,and their use as herbicides.Novel intermediates of the formulae ##STR4## in which formulae R, X, m, n and a have the meanings given above,Z.sup.1 is a halogen atom andm is a hydrogen atom or an alkali metal atom.Type: GrantFiled: April 11, 1983Date of Patent: February 19, 1985Assignee: Nihon Tokushu Noyaku Seizo K.K.Inventors: Junichi Saito, Kazuomi Yasui, Kozo Shiokawa, Atsumi Kamochi
-
Patent number: 4490552Abstract: A novel process for the preparation of aryl esters of organic carboxylic acids in high isomer purity by decomposing a compound of the formula ##STR1## wherein Ar is an aryl radical, X is an acyloxy of an organic carboxylic acid and Y is selected from the group consisting of an acyloxy of an organic carboxylic acid and an anion of a strong organic and mineral acid in an aqueous media in the presence of a palladium salt or in the form of a two-phase reaction, wherein the aryl thallium salt is dissolved in water and the catalytic palladium salt is dissolved in a water-immiscible organic solvent and the reaction takes place with mixing.Type: GrantFiled: December 20, 1982Date of Patent: December 25, 1984Assignee: Rutgerswerke AGInventor: Ulrich Knips
-
Patent number: 4479900Abstract: Compounds of the formula: ##STR1## wherein R.sup.1 is lower alkyl or benzyl. R.sup.2 is lower alkoxy, benzyloxy, or the group ##STR2## where R.sup.3 is lower alkoxy; and Ar is phenyl optionally substituted with 1 to 3 substituents independently selected from halogen, trihalomethyl, nitro or lower alkyl, show plant growth regulating activity.Type: GrantFiled: April 29, 1983Date of Patent: October 30, 1984Assignee: Chevron Research CompanyInventor: Tatao Luo
-
Patent number: 4476319Abstract: A new compound derived from p-chlorophenoxyacetic acid, the p-chlorophenocetate of 1-aminoadamantine-2-ethanol of the following structural formula I: ##STR1## as well as its pharmaceutically acceptable salts, possessing properties for the treatment of various pathological conditions of the central nervous system. Also disclosed are its method of preparation; pharmaceutical compositions containing the said compounds; and the treatment of various pathological conditions of the central nervous system with the use of the said compositions.Type: GrantFiled: October 27, 1982Date of Patent: October 9, 1984Assignee: Sociedad Espanola de Especialidades Farmaco-Terapeuticas S.A.Inventors: Romeo R. Andreoli, Xavier D. Cirera
-
Patent number: 4468247Abstract: Salts, esters, amides, hydrazides and hydroxyamides of 4-methyl-4-[3'-(4"-trifluoromethylphenoxy)-phenoxy]crotonic acid are herbicidal against broad leaf plants.Type: GrantFiled: June 22, 1982Date of Patent: August 28, 1984Assignee: Chevron Research CompanyInventor: David C. K. Chan
-
Patent number: 4456768Abstract: Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the following positions 4,4; 7,7; 10,10; and 5.Type: GrantFiled: May 1, 1981Date of Patent: June 26, 1984Assignee: The University of ChicagoInventor: Josef Fried
-
Patent number: 4450172Abstract: Polyhalohydroxyisopropyl phenylalka(e)noic acid esters of alkylaminohydroxypropyloxyphenylalkyl alcohols, such as 2-(4-((2-hydroxy-3-(1-methylethylamino)-phenyl)ethyl 3-(4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl))benzene propanoate, are useful as antihypertensive agents. Preferred compounds give vasodilatory activity and reduced tachycardia.Type: GrantFiled: March 10, 1982Date of Patent: May 22, 1984Assignee: E. I. Du Pont de Nemours and CompanyInventor: Sung-eun Yoo
-
Patent number: 4444788Abstract: Compounds of the formula ##STR1## wherein the 9-chlorine atom can be in the .alpha.- or .beta.-position,R.sub.1 is OR.sub.2, or NHR.sub.3 wherein R.sub.3 is H or the acyl group ofa C.sub.1-15 hydrocarbon carboxylic or sulfonic acid;A is --CH.sub.2 --CH.sub.2 -- or cis--CH.dbd.CH--,B is --CH.sub.2 --CH.sub.2 --,trans--CH.dbd.CH--, or --C.tbd.C--, ##STR2## wherein the OH-group in each case can be in the .alpha.- or .beta.-position, and can be etherified or esterified by tetrahydropyranyl, tetrahydrofuranyl, .alpha.-ethoxyethyl, trimethylsilyl dimethyl, tert-butylsilyl, tribenzylsilyl, acetyl, propionyl, butyryl or benzoyl;D and E together represent a direct bond orD is a straight-chain or branched alkylene group of 1-10 carbon atoms, optionally substituted by fluorine, andE is oxygen or sulfur or a direct bond, andR.sub.4 is hydroxy or hydroxy etherified or esterified as defined for W above;R.sub.5 is a C.sub.1-10 hydrocarbon aliphatic group; a C.sub.Type: GrantFiled: June 10, 1982Date of Patent: April 24, 1984Assignee: Schering AktiengesellschaftInventors: Werner Skuballa, Bernd Raduechel, Helmut Vorbrueggen, Walter Elger, Olaf Loge, Ekkehard Schillinger
-
Patent number: 4441913Abstract: Novel substituted phenoxypropionates of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently are a hydrogen atom or a C.sub.1 to C.sub.6 alkyl group,X is a hydrogen or halogen atom, nitro, C.sub.1 to C.sub.6 alkyl or C.sub.1 to C.sub.6 alkoxy,a and n each independently are 1 or 2, andAr is a group of the formula ##STR2## wherein Y is a trifluoromethyl group, a halogen atom ora nitro, cyano or C.sub.1 to C.sub.6 alkyl group, andb is 1, 2 or 3,and their use as herbicides.Novel intermediates of the formulae ##STR3## in which formulae R.sup.1, R.sup.2, X, a and n have the meanings given above andZ.sup.1 represents halogen.Type: GrantFiled: June 17, 1982Date of Patent: April 10, 1984Assignee: Nihon Tokushu Noyaku Seizo K.K.Inventors: Masahiro Aya, Junichi Saito, Kazuomi Yasui, Kozo Shiokawa, Koichi Moriya
-
Patent number: 4429167Abstract: This invention relates to 3-alkoxy-4-substituted-phenoxy-2,3-unsaturated acid esters and derivatives thereof and the use of said acid esters and derivatives for the control of weeds.Type: GrantFiled: January 22, 1982Date of Patent: January 31, 1984Assignee: Zoecon CorporationInventor: Shy-Fuh Lee
-
Patent number: 4424394Abstract: Arylacetic acids and their esters, of the formula Ar(CH.sub.2 -COOR).sub.n (where Ar=aryl, R is H or a hydrocarbon radical, and n is 1 or 2) are manufactured by carbonylation of halomethylaryl compounds Ar(CH.sub.2 C).sub.n (where X is Cl, Br or I) with carbon monoxide and a catalyst m.sup.+ ?Fe(O).sub.3 NO!.sup.- (where M is an alkali metal, ammonium or one equivalent of an alkaline earth metal) in the presence of stoichiometric amounts of an inorganic base or of an alcoholate of an alcohol ROH.Type: GrantFiled: November 8, 1979Date of Patent: January 3, 1984Assignee: BASF AktiengesellschaftInventors: Kurt Schneider, Rudolf Kummer, Kurt Schwirten, Hans-Dieter Schindler, deceased, Maria E. Schindler, heir-at-law, Ute Lang, heir-at-law, Rainer Schindler, heir-at-law
-
9-Deoxy-9-methylene derivatives of (dl)-16-phenoxy and 16-phenoxy substituted prostatriene compounds
Patent number: 4418206Abstract: Novel compounds of the formula: ##STR1## wherein A is CHOH, CHO or COOR; R is hydrogen or a lower alkyl group of 1 to 4 carbon atoms; and the pharmaceutically acceptable, non-toxic salts of compounds in which R is hydrogen; and X is hydrogen, o-, m- or p-halo(fluoro, chloro or bromo), o-, m- or p-methyl or o-, m- or p-methoxy. These compounds possess prostaglandin-like activity and thus are useful in the treatment of mammals where prostaglandins are indicated. They are particularly useful as inhibitors of gastric acid secretions and as agents for the control of asthmatic attack, because of their bronchodilating activity.Type: GrantFiled: March 22, 1982Date of Patent: November 29, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Douglas L. Wren -
Patent number: 4416687Abstract: 3,5-Bis (trifluoromethyl)phenoxy carboxylic acids and derivatives thereof have been found to reduce herbicidal injury of certain food crops, especially grain sorghum, due to the application thereto of herbicides that kill or control weeds that impede the yield of the crops.Type: GrantFiled: February 1, 1982Date of Patent: November 22, 1983Assignee: Monsanto CompanyInventors: John J. D'Amico, Tann R. Schafer
-
Patent number: 4415746Abstract: This disclosure describes novel 16-aryloxy-17,18,19,20-tetranoprostanoic acids and derivatives thereof useful as bronchodilators and as hypotensive and contraceptive agents.Type: GrantFiled: October 5, 1981Date of Patent: November 15, 1983Assignee: American Cyanamid CompanyInventors: Charles V. Grudzinskas, Martin J. Weiss
-
Patent number: 4415354Abstract: Compounds of the formula ##STR1## wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group,Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, andZ is a substituted alkoxy group,and compositions containing these compounds exhibit herbicidal activity.Type: GrantFiled: September 16, 1981Date of Patent: November 15, 1983Assignee: Rohm and Haas CompanyInventors: Horst O. Bayer, Colin Swithenbank, Roy Y. Yih
-
Patent number: 4414017Abstract: Compounds of the formula ##STR1## wheren X.sup.1 is halo or trihalomethyl, X.sup.2 is hydrogen or halo, R.sup.1 is nitro or --OR.sup.3, R.sup.2 is hydrogen or --OR.sup.4, R.sup.3 ##STR2## R.sup.4 is ##STR3## and R is hydroxy, alkoxy, alkenoxy, alkynoxy, thiol, alkythio, alkenylthio, amino, mono- or di-substituted amino or OM, wherein M is a monovalent cation; R' and R" are hydrogen, alkyl, alkenyl, alkynyl or phenyl; and Y is oxygen, sulfur, or substituted or unsubstituted nitrogen, have herbicidal activity.Type: GrantFiled: May 27, 1980Date of Patent: November 8, 1983Assignee: Chevron Research CompanyInventor: David C. K. Chan
-
Patent number: 4412998Abstract: Novel hypolipidemic nicotinates and related esters, being phenoxy organic compounds, are disclosed, as well as pharmaceutical compositions thereof and method of treating hyperlipidemia therewith.Type: GrantFiled: November 27, 1981Date of Patent: November 1, 1983Assignee: Merz & CompanyInventors: Arthur Scherm, Dezsoe Peteri, Klaus Hummel
-
Patent number: 4406814Abstract: Disclosed is a new family of Liquid Crystalline Materials for use in optical display devices having the general formula: ##STR1## The members of the family of materials are characterized by having a broad nematic operating range in conjunction with low viscosity and exhibit fast response times to a controlled electrical field in the lower temperature regions of their nematic operating range and may be mixed with other members of the family or with other liquid crystalline materials and/or homologous non-liquid crystalline materials.Type: GrantFiled: April 10, 1981Date of Patent: September 27, 1983Assignee: Eaton CorporationInventor: Joseph P. Ferrato
-
Patent number: 4404396Abstract: Process for the preparation of 2-(2,4-dichlorophenoxy)phenylacetic acid in which the potassium salts of 2-chlorophenylacetic acid and 2,4-dichlorophenol are reacted in aromatic hydrocarbon solvents at elevated temperatures in the presence of a copper chloride catalyst, followed thereafter by acidification.Type: GrantFiled: January 11, 1982Date of Patent: September 13, 1983Assignee: Reckitt & Colman Products LimitedInventors: Colin Thomson, Neil J. Tweddle
-
Patent number: 4402855Abstract: A family of liquid crystals having a type A smectic mesophase with a positive dielectric anisotropy, which are particularly useful in the case of the thermo-optical effect.The substances of the family are in accordance with the general formula: ##STR1## in which R represents an organic group of the alkyl or alkoxy type containing 1 to 15 carbon atoms and in which X and Y designate either the bromine or the nitrile radical.Type: GrantFiled: July 15, 1981Date of Patent: September 6, 1983Assignee: Thomson-CSFInventors: Annie Zann, Jean-Claude Dubois
-
Patent number: 4380661Abstract: 2-[p-(p-substituted phenoxy)phenoxy]propionyl oximes, processes for their preparation, herbicidal compositions containing these oximes and methods of use of the herbicidal compositions are disclosed.Type: GrantFiled: February 23, 1981Date of Patent: April 19, 1983Assignee: Hoffmann-La Roche Inc.Inventor: Milos Suchy
-
Patent number: 4370489Abstract: Compounds of the formula ##STR1## in which R represents hydroxyl, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.6)alkylthio, (C.sub.2 -C.sub.4)alkenyloxy, cyclohexyloxy, cyclopentyloxy, phenoxy or phenylthio both optionally substituted once or twice with halogen, benzyloxy, benzylthio or -O-cat in which "cat" stands for the cation of an inorganic or organic base, have a very good effect on wild oat, barnyard grass, bristle grass and rayegrass in a much lower concentration than known analogous compounds.Type: GrantFiled: January 14, 1977Date of Patent: January 25, 1983Assignee: Hoechst AktiengesellschaftInventors: Heinz Boesenberg, Gerhard Horlein, Helmut Kocher, Peter Langeluddeke
-
Patent number: 4368135Abstract: Anisotropic compounds with negative or positive DCA and .DELTA.n.ltoreq.0.2 have the formula (1) ##STR1## in which R.sup.1 and R.sup.2 l are independently hydrogen, alkyl, alkoxy having 1 to 12 carbon atoms respectively, or one of R.sup.1 and R.sup.2 can represent cyclical fragment of formulae (1a) or (1b); ##STR2## the bridges Z.sup.1, Z.sup.2 and Z.sup.3 are identical or different and means covalent bonds or carboxyl or oxycarbonyl groups; R.sup.3 is hydrogen, alkyl or alkoxy group having 1 to 12 carbon atoms, respectively; X.sup.1 and X.sup.4 are independently hydrogen, halogen, nitrile or nitro, wherein at least one of X.sup.1 and X.sup.4 is not hydrogen when R.sup.2 represents a cyclical fragment of formula (1a) or (1b) and Z.sup.2 is a carboxyl group or Z.sup.3 is an oxycarbonyl group, respectively. Liquid crystal compositions are also disclosed.Type: GrantFiled: June 30, 1980Date of Patent: January 11, 1983Assignee: BBC, Brown, Boveri & Company, Ltd.Inventor: Maged A. Osman
-
Patent number: 4365991Abstract: Propionic acid oximes of the general formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of from 1 to 6 carbon atoms or cycloalkyl of from 3 to 6 carbon atoms, R.sub.2 is hydrogen, alkyl of from 1 to 6 carbon atoms, alkenyl of from 2 to 6 carbon atoms or alkynyl of from 2 to 6 carbon atoms, or R.sub.1 and R.sub.2 together with the carbon atom to which they are attached form a cyclopentane or cyclohexane ring which can be mono-, di- or trisubstituted with alkyl of from 1 to 3 carbon atoms, R.sub.3 is hydrogen, halogen or nitro with the proviso that R.sub.1 and R.sub.2 are not simultaneously hydrogen, processes for their manufacture, herbicidal compositions containing these compounds as the active ingredient and methods of use of the herbicidal compositions are disclosed.Type: GrantFiled: March 6, 1981Date of Patent: December 28, 1982Assignee: Hoffmann-La Roche Inc.Inventor: Wijitha de Silva
-
Patent number: 4360375Abstract: A herbicidal composition which comprises a phenoxyphenoxy unsaturated derivative having the formula: ##STR1## wherein X represents a halogen atom or CF.sub.3 ; Y represents a hydrogen atom or a halogen atom; and Z represents --COOR, --COR", --COOH, --CH.sub.2 OH, or --CH.sub.2 OR"'.Type: GrantFiled: December 23, 1980Date of Patent: November 23, 1982Assignee: Kumiai Chemical Industry Co., Ltd.Inventors: Kazuo Jikihara, Shigekazu Itoh, Shuichi Takayama, Koichi Sato, Ichiro Kimura, Isao Chiyomaru
-
Patent number: RE31715Abstract: Novel liquid crystal compounds are disclosed, which are chiral esters based upon the phenol ##STR1## Typical examples are: ##STR2## and mixtures of these compounds have a helical pitch such that the mixtures reflect light of a specific wavelength when illuminated with ordinary light and the pitch is temperature sensitive so that the mixtures can be used in temperature indicating devices. Specific examples are given as are samples of mixtures that can be used in phase change electro-optic display devices.Type: GrantFiled: March 27, 1981Date of Patent: October 30, 1984Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern IrelandInventors: David Coates, George W. Gray, Damien G. McDonnell