Polyoxy Alcohol Moiety Patents (Class 560/63)
  • Patent number: 4227009
    Abstract: Phenoxyphenoxy-propionic acid derivatives of the formula ##STR1## exhibit an outstanding herbicidal activity against a wide variety of weed grasses and are well tolerated by dicotyledonous crop plants and various cereals.
    Type: Grant
    Filed: May 24, 1977
    Date of Patent: October 7, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Koch, Reinhard Handte, Gerhard Horlein, Heinrich Leditschke, Helmut Kocher, Peter Langeluddeke
  • Patent number: 4225533
    Abstract: Novel esters of ether and thioether substituted cyclopropanecarboxylic acids, synthesis thereof, and intermediates therefor, such esters being useful as pesticides.
    Type: Grant
    Filed: June 1, 1979
    Date of Patent: September 30, 1980
    Assignee: Zoecon Corporation
    Inventor: Clive A. Henrick
  • Patent number: 4182761
    Abstract: Acyloxy-substituted aryloxyalkyl diketones, useful as anti-viral agents, are prepared either by esterification of the corresponding hydroxy-substituted compounds or by reacting a haloalkyl diketone with an alkali metal salt of an acyloxy-substituted phenol.
    Type: Grant
    Filed: June 7, 1978
    Date of Patent: January 8, 1980
    Assignee: Sterling Drug Inc.
    Inventors: Joseph C. Collins, Guy D. Diana
  • Patent number: 4175947
    Abstract: Phenoxy-phenoxypropionic acid derivatives of the formula ##STR1## wherein R is hydrogen or halogen, and R.sub.1 is substituted alkyl, cyclohexenyl, phenylalkenyl or (substituted) alkinyl, are interesting selective herbicides having a special activity against weed grasses. They are obtained for example by reaction of corresponding phenoxypropionic acid halides with hydroxy compounds of the formula HO--R.sub.1.
    Type: Grant
    Filed: April 21, 1977
    Date of Patent: November 27, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Koch, Reinhard Handte, Gerhard Horlein, Hermann Bieringer, Peter Langeluddeke
  • Patent number: 4169720
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, chlorine or fluorine; andR.sub.3 is --CH.sub.2 OH, --CH.sub.2 --O--COR.sub.4, --CH.sub.2 --O--CONHR.sub.5, --COOH, --COOCat, --COOR.sub.6, --CONR.sub.7 R.sub.8 or --CO--SR.sub.9 ;where Cat is one equivalent of an inorganic or organic cation;R.sub.4 is hydrogen or alkyl of 1 to 10 carbon atoms;R.sub.5 is alkyl of 1 to 4 carbon atoms, phenyl or halo-substituted phenyl;R.sub.6 is alkyl of 1 to 10 carbon atoms which may optionally have a chloro, hydroxyl, lower alkoxy, lower alkoxy-lower alkoxy, lower alkylthio, amino, mono-lower alkyl-amino, di-lower alkyl-amino, allyloxy or phenoxy substituent attached thereto; phenyl; benzyl; monochloro-benzyl; dichloro-benzyl; cyclohexyl; 1-ethynyl-cyclohexyl; lower alkenyl; lower alkynyl; --N.dbd.C(CH.sub.3).sub.2 ; 2--(2',4',5'-trichloro-phenoxy)-ethyl, 2-(2', 5'-dichloro-4'-bromo-phenoxy)-ethyl; or ##STR2## R.sub.
    Type: Grant
    Filed: July 28, 1977
    Date of Patent: October 2, 1979
    Assignee: Celamerck GmbH & Co. KG
    Inventors: Erich Schacht, Gunter Lauterbach, Werner Mehrhof, Jurgen Curtze, Gerbert Linden, Siegmund Lust, Klaus Thomas
  • Patent number: 4168385
    Abstract: This invention discloses .alpha.-aryloxy or .alpha.-arylthio para substituted phenyl acetic acid compounds that are useful in lowering sterol and triglyceride serum levels.
    Type: Grant
    Filed: February 17, 1977
    Date of Patent: September 18, 1979
    Assignee: American Cyanamid Company
    Inventors: Ronald I. Trust, Francis J. McEvoy, Jay D. Albright
  • Patent number: 4168386
    Abstract: The present invention relates to novel 9-deoxy-9-methylene-inter-phenylene-13,14-didehydro-16-phenyl-17,18,19,20- tetranor-PGF.sub.1 compounds. These compounds are useful pharmacological agents, and are useful for the same purposes as the corresponding PGE-type compounds.
    Type: Grant
    Filed: July 12, 1978
    Date of Patent: September 18, 1979
    Assignee: The Upjohn Company
    Inventor: Gordon L. Bundy
  • Patent number: 4166912
    Abstract: The present invention relates to novel 9-deoxy-9-methylene-inter-phenylene-16-phenyl-PGF compounds.These compounds are useful pharmacological agents, and are useful for the same purposes as the corresponding PGE-type compounds.
    Type: Grant
    Filed: July 12, 1978
    Date of Patent: September 4, 1979
    Assignee: The Upjohn Company
    Inventor: Gordon L. Bundy
  • Patent number: 4156011
    Abstract: The sulphur- and oxygen-containing diaryl compounds of the formula: ##STR1## in which A and B, which may be the same or different, represent O, S, SO or SO.sub.2,Alk is a C.sub.1 -C.sub.4 hydrocarbon radical with a straight or branched chain, R represents COOH, an esterified COOH group, a carboxylic amide group, OH, O-SO.sub.2 CH.sub.3, NH.sub.2, NHR.sub.1, NR.sub.1 R.sub.2, NHZOH, NHZNR.sub.1 R.sub.2, C(.dbd.NH)NH.sub.2, C(.dbd.NH)NHOH or 2-.DELTA..sup.2 -imidazolinyl, Z is a C.sub.2 -C.sub.4 hydrocarbon radical with a straight or branched chain, and R.sub.1 and R.sub.2 each represent a C.sub.1 -C.sub.
    Type: Grant
    Filed: April 5, 1977
    Date of Patent: May 22, 1979
    Assignee: Societe Anonyme dite: Laboratoire L. Lafon
    Inventors: Victor Lafon, Louis Lafon
  • Patent number: 4153803
    Abstract: Compounds possessing pharmaceutical activity as substances able to lower the level of fatty substances in the blood possess the following general formula: ##STR1## wherein R represents hydrogen, halogen, hydroxy or alkyl or alkoxy containing from 1 to 4 carbon atoms;A.sup.1 and A.sup.2 which can be the same or different are hydrogen or alkyl containing from 1 to 9 carbon atoms such that A.sup.1 and A.sup.
    Type: Grant
    Filed: March 1, 1977
    Date of Patent: May 8, 1979
    Assignee: Siegfried Aktiengesellschaft
    Inventors: Kurt Thiele, Quazi Ahmed, Rudolf Adrian, Ulrich Jahn
  • Patent number: 4118583
    Abstract: Therapeutically active compounds of the general formula: ##STR1## wherein Ac.sub.1 is a first acyl group, Ac.sub.2 is a second acyl group different from Ac.sub.1, A is a C--C bond or a divalent organic residue; R.sub.1, R.sub.2 are a hydrogen atom or a lower alkyl group, R.sub.1 and R.sub.2 together being able to take part in the formation of a ring having up to 6 atoms, A, R.sub.1 and R.sub.2 may be substituted by -OH groups esterified or not by acyl groups.
    Type: Grant
    Filed: December 6, 1976
    Date of Patent: October 3, 1978
    Assignee: Laboratories om Societe Anonyme
    Inventors: Pierre Baudet, Jean-Paul Ricard, Adrian Schulthess
  • Patent number: 4113966
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: August 1, 1977
    Date of Patent: September 12, 1978
    Assignee: The Upjohn Company
    Inventor: Herman W. Smith
  • Patent number: 4113965
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: August 1, 1977
    Date of Patent: September 12, 1978
    Assignee: The Upjohn Company
    Inventor: Herman W. Smith
  • Patent number: 4073876
    Abstract: In the preparation of glycol esters by the oxidation of an olefin in the presence of a catalyst comprising tellurium, wherein the accumulation of foreign metals in association with the tellurium catalyst component has an adverse effect upon the reaction, such foreign metals are maintained at low levels while the tellurium catalyst values are recovered for recycling in high yield by purging a portion of a high-boiling residual fraction produced in the distillation treatment of the reaction mixture and treating the purged portion with water and/or an aqueous alkaline solution.
    Type: Grant
    Filed: July 1, 1976
    Date of Patent: February 14, 1978
    Assignee: Halcon International, Inc.
    Inventor: Vijai P. Gupta
  • Patent number: 4072754
    Abstract: Hydratropic acid derivatives of the formula ##STR1## wherein R.sub.1 is H, alkyl of 1-4 carbon atoms, 2-acetamidoethyl, 1-methyl-4-piperidyl, or 2,3-dihydroxypropyl, and R.sub.2 is Hal, phenyl, 4-Hal-phenyl, 4-Hal-phenoxy, 4-Hal-phenoxymethyl, 1,2,3,4-tetrahydro-1-naphthyl, 1-pyrryl, piperidino, isoindolino, 1,2,3,4-tetrahydroquinolino, 1,2,3,4-tetrahydro-4-quinolyl or 1-methyl-1,2,3,4-tetrahydro-4-quinolyl, Hal being F, Cl, or Br, and the physiologically acceptable salts thereof, which possess cholesterol and triglyceride serum-level-lowering activity, can be prepared by reacting a phenol of the formula ##STR2## with a compound of the formula X--C(CH.sub.3)(C.sub. 6 H.sub.5)--COOR.sub.1 wherein X represents Cl, Br, I, OH, or esterified OH.
    Type: Grant
    Filed: November 25, 1974
    Date of Patent: February 7, 1978
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Erich Schacht, Werner Mehrhof, Zdenek Simane, Herbert Nowak, Detlev Kayser
  • Patent number: 4065432
    Abstract: Thermally stable, rigid bisphenols of the formula ##STR1## WHERE R is ##STR2## or ##STR3## where R.sup.2 is arylene or substituted arylene, andR.sup.1 is hydrogen or acyl,Are used to prepare thermally stable, rigid, ordered polyesters of the formula ##STR4## where R.sup.4 is arylene or substituted arylene, andn is at least about 10.
    Type: Grant
    Filed: December 16, 1976
    Date of Patent: December 27, 1977
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: August Henry Frazer
  • Patent number: 4055595
    Abstract: Derivatives of 2-hydroxy-3,3,3-trifluoro-2-(alkyl or trifluoromethyl)propionic acid bearing a phenyl or naphthyl group linked to the 2-hydroxy group either directly or via an intermediate methylene group. The compounds reduce the concentrations of cholesterol, total esterified fatty acids or fibrinogen in the blood plasma of test animals and some compounds show anti-arthritic properties.
    Type: Grant
    Filed: November 10, 1975
    Date of Patent: October 25, 1977
    Assignee: Imperial Chemical Industries Limited
    Inventors: David Bryan Haydock, Thomas Patrick Cunningham Mulholland, Jeffrey Meyrick Thorp