Nitrogen Attached Indirectly To The Sulfonate Group By Acyclic Nonionic Bonding Patents (Class 562/104)
  • Patent number: 10071955
    Abstract: The high-yield circular production method of taurine includes the following steps: S1, ethylene oxide reacts with sodium bisulfite solution to generate sodium hydroxyethyl sulfonate; S2, sodium hydroxyethyl sulfonate obtained in S1 is subjected to ammonolysis reaction in ammonia, and ammonia gas is recycled through flash evaporation upon completion of the reaction; S3, a reaction solution obtained after flash evaporation in S2 is sent to pass through an acidic cation exchange resin column, a material liquid containing taurine is collected, the inactivated resin column is subjected to regeneration with sulfur dioxide or carbon dioxide aqueous solution, and an eluent acquired during regeneration can be recycled directly or recycled after treated by sulfur dioxide; S4, the material liquid collected in S3 is subjected to post treatment to acquire taurine.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: September 11, 2018
    Assignee: QIANJIANG YONGAN PHARMACEUTICAL Co., Ltd.
    Inventors: Yong Chen, Xiquan Fang, Shaobo Li
  • Patent number: 9815778
    Abstract: There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is reacted with ammonium isethionate to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: November 14, 2017
    Assignee: VITAWORKS IP, LLC
    Inventor: Songzhou Hu
  • Patent number: 9598360
    Abstract: A cyclic process is disclosed for the production of taurine from alkali vinyl sulfonate in a high overall yield by continuously converting the byproducts of the ammonolysis reaction, sodium ditaurinate and sodium tritaurinate, to sodium taurinate. Sodium sulfate and residual taurine in the crystallization mother liquor are efficiently separated by converting taurine into a highly soluble form of sodium taurinate or ammonium taurinate while selectively crystallizing sodium sulfate.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 21, 2017
    Assignee: VITAWORKS IP, LLC
    Inventor: Songzhou Hu
  • Patent number: 9593076
    Abstract: There is disclosed a process for producing taurine by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is neutralized with isethionic acid to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: March 14, 2017
    Assignee: Vitaworks IP, LLC
    Inventor: Songzhou Hu
  • Patent number: 9428451
    Abstract: A cyclic process is disclosed for the production of taurine from alkali isethionate in a high overall yield by continuously converting the byproducts of the ammonolysis reaction, sodium ditaurinate and sodium tritaurinate, to sodium taurinate. Sodium sulfate and residual taurine in the crystallization mother liquor are efficiently separated by converting taurine into a highly soluble form of sodium taurinate or ammonium taurinate while selectively crystallizing sodium sulfate.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: August 30, 2016
    Inventor: Songzhou Hu
  • Patent number: 8956799
    Abstract: A photoacid generator includes those of formula (I): wherein each Ra in formula 1 is independently H, F, a C1-10 nonfluorinated organic group, C1-10 fluorinated organic group, or a combination comprising at least one of the foregoing, provided at least one Ra is F or a C1-10 fluorinated organic group, the C1-10 fluorinated and nonfluorinated organic groups each optionally comprising O, S, N, or a combination comprising at least one of the foregoing heteroatoms; L1 is a linking group comprising a heteroatom comprising O, S, N, F, or a combination comprising at least one of the foregoing; G+ is an onium salt of the formula (II): wherein in formula (II), X is S or I, each R0 is independently C1-30 alkyl group; a polycyclic or monocyclic C3-30 cycloalkyl group; a polycyclic or monocyclic C4-30 aryl group; or a combination comprising at least one of the foregoing, provided at least one R0 is substituted where each R0 is a C6 monocyclic aryl group, and wherein when X is I, a is 2, and where X is S, a is 3,
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: February 17, 2015
    Assignee: Rohm and Haas Electronic Materials LLC
    Inventors: Emad Aqad, Cheng-Bai Xu, Mingqi Li, William Williams, III
  • Patent number: 8900794
    Abstract: A photoacid generator compound has the formula (I): [A-(CHR1)p]k-(L)-(CH2)m—(C(R2)2)n—SO3?Z+??(I) wherein A is a substituted or unsubstituted, monocyclic, polycyclic, or fused polycyclic C5 or greater cycloaliphatic group optionally comprising O, S, N, F, or a combination comprising at least one of the foregoing, R1 is H, a single bond, or a substituted or unsubstituted C1-30 alkyl group, wherein when R1 is a single bond, R1 is covalently bonded to a carbon atom of A, each R2 is independently H, F, or C1-4 fluoroalkyl, wherein at least one R2 is not hydrogen, L is a linking group comprising a sulfonate group, a sulfonamide group, or a C1-30 sulfonate or sulfonamide-containing group, Z is an organic or inorganic cation, p is an integer of 0 to 10,k is 1 or 2, m is an integer of 0 or greater, and n is an integer of 1 or greater.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: December 2, 2014
    Assignee: Rohm and Haas Electronic Materials LLC
    Inventors: Emad Aqad, Cheng-Bai Xu, Mingqi Li, Shintaro Yamada, William Williams, III
  • Publication number: 20140314779
    Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 23, 2014
    Applicant: GENENTECH, INC.
    Inventors: Natarajan VIJAYASANKARAN, Steven J. MEIER, Sharat VARMA, Yi YANG
  • Publication number: 20140243282
    Abstract: The present invention relates to novel drug conjugates, where in two drugs are linked together through an appropriate linker having at least two functional groups capable of forming covalent bond with drugs D1 and D2. The invention also relates to developing novel compositions, methods for their preparation and their use in treating various disease conditions.
    Type: Application
    Filed: December 12, 2011
    Publication date: August 28, 2014
    Inventor: Satish Reddy Kallam
  • Publication number: 20140243552
    Abstract: A reactive emulsifier comprising a compound of formula (I), which makes polymerization stability satisfactory and is capable of improving the water resistance etc. of the polymer film to be obtained. In the formula (I), D represents a polymerizable unsaturated group represented by the chemical formula D-1 or D-2; m1 represents a number of 1 or larger; R1 represents an alkyl group having 1 to 12 carbon atoms; m2 represents a number of 0 to 4; and the sum of m1 and m2 is 1 to 5. R2 represents a hydrocarbon group having 6 to 30 carbon atoms; A represents either an alkylene group or a substituted alkylene group which has 2 to 4 carbon atoms; and n is in the range of 0 to 1,000. X represents a hydrogen atom or an anionic hydrophilic group which is —(CH2)a—SO3M etc. R3 represents a hydrogen atom or methyl.
    Type: Application
    Filed: September 18, 2012
    Publication date: August 28, 2014
    Applicant: Dai-ichi Kogyo Seiyaku Co., Ltd.
    Inventors: Asako Ogasawara, Masayuki Hashimoto
  • Patent number: 8816078
    Abstract: Compositions and methods related to the removal of acidic gas. In one embodiment, compositions and methods are provided for the removal of acidic gas from a gas mixture using an aqueous amine solvent comprising water, a first amine, and a second amine, wherein the first amine contributes at least 50% by weight of the solvent's total amine concentration.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: August 26, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Gary Rochelle, Stephanie Freeman, Xi Chen, Thu Nguyen, Alexander Voice, Humera Rafique
  • Publication number: 20140170054
    Abstract: One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines, aryl amines or tertiary amines. The TSILs may be used for gas capture, capitalizing on their non-volatile nature. In certain embodiments, the captured gas is selected from the group consisting of CO2, SO2, CS2, and NO2. Another aspect of the present invention relates to a library of CO2-philic salts, which library facilitates reactive gas separation. In certain embodiments, the CO2-philic salts are CO2-reactive TSILs. In certain embodiments, the CO2-philic salts are resinous or plastic in nature.
    Type: Application
    Filed: September 17, 2013
    Publication date: June 19, 2014
    Applicant: University of South Alabama
    Inventor: James H. Davis, JR.
  • Publication number: 20140158621
    Abstract: The present invention relates to a thermo-responsive draw solute that can be applied to water desalination and purification based on forward osmosis. The thermo-responsive draw solute has a molar mass of 50 to 3000 g/mol and undergoes a phase transition at a temperature of 0° C. to 70° C. The thermo-responsive draw solute creates optimum conditions for the desalination of seawater and the purification of contaminated water based on forward osmosis. The present invention also relates to a method for water desalination and purification using the thermo-responsive draw solute. The method consumes little energy for water desalination or purification, is simple to apply to water desalination or purification, and enables separation of the draw solute in a very easy manner.
    Type: Application
    Filed: July 27, 2012
    Publication date: June 12, 2014
    Applicant: SNU R&DB FOUNDATION
    Inventors: Yan Lee, Minwoo Noh, Yeongbong Mok, Heejin Kim, Seonju Lee, Daichi Nakayama
  • Publication number: 20140121405
    Abstract: The present disclosure provides a process for producing taurine, includes: adjusting a PH value of a sodium taurate solution by a S4+ compound; introducing ethylene oxide into the sodium taurate solution to produce sodium hydroxyethyl sulfonate; separating crude taurine before or after introducing the ethylene oxide to the solution; and adding ammonia to the sodium hydroxyethyl sulfonate reaction solution to be reacted with the reaction solution to reproduce sodium taurate. The process for producing taurine of the present disclosure makes use of the balances of the sodium bases in the system, recycles the mother liquor until the sodium taurate is reproduced out of the reactions in the mother liquor, and thus is capable of allowing taurine to be synthesized and extracted.
    Type: Application
    Filed: February 19, 2013
    Publication date: May 1, 2014
    Applicant: QIANJIANG YONGAN PHARMACEUTICAL CO., LTD
    Inventor: Yong Chen
  • Publication number: 20140107027
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: December 18, 2013
    Publication date: April 17, 2014
    Applicant: BHI LIMITED PARTNERSHIP
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
  • Patent number: 8609890
    Abstract: A method is disclosed for the production of taurine by a cyclic process of reacting ethylene oxide with sodium bisulfite and ammonium to obtain sodium taurinate. After excess ammonia is removed from the reaction mixture, sodium taurinate is neutralized with sulfur dioxide or sulfurous acid to recover taurine and to regenerate sodium bisulfate, which is then reacted with ethylene oxide.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: December 17, 2013
    Inventor: Songzhou Hu
  • Publication number: 20130316248
    Abstract: The invention relates to a method for producing perfluoroalkanesulfonic acid esters and for further transforming the same into the salts thereof. The invention also relates to the use of the produced compounds in electrolytes, batteries, capacitors, supercapacitors, and galvanic cells.
    Type: Application
    Filed: July 8, 2009
    Publication date: November 28, 2013
    Inventors: Nikolai Ignatyev, Michael Schmidt, Udo Heider, Peter Sartori, Andry Kucheryna
  • Patent number: 8563769
    Abstract: A fluorine-containing compound exhibiting excellent surface tension-reducing ability despite the absence of perfluoroalkyl group having a chain length of 8 or more which had been the cause of the PFOS and PFOA problems and use of a fluorine material with low environmental load is provided. Also provided are a fluorine-containing surfactant and a composition thereof, an aqueous resin emulsion and a floor polish composition containing such surfactant. The fluorine-containing compound is represented by the following formula (1): Rf1—CpH2p—CH(OH)—CqH2q—NR—CrH2r—(O)n—SO3M (1) wherein Rf1 is a C1-6 perfluoroalkyl group, p, q, and r are independently an integer of 1 to 6, M is a cationic atom or atomic group, n is 0 or 1, R is hydrogen atom, a C1-12 alkyl group, or a group represented by the following formula (2): Rf2—CsH2s—CH(OH)—CtH2t—??(2) wherein Rf2 is a C1-6 perfluoroalkyl group, and s and t are independently an integer of 1 to 6.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: October 22, 2013
    Assignee: AGC Seimi Chemical Co., Ltd.
    Inventors: Katsuyuki Tsugita, Masato Mitsuhashi
  • Publication number: 20130256228
    Abstract: This disclosure describes draw solution compositions for FO processes which increase the available membrane area for permeation and are also amenable to reconcentration with standard techniques, such as membrane filtration and evaporative technologies. The composition are comprised of a water soluble draw solute having surface active properties, i.e., a surfactant.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 3, 2013
    Inventors: Upen J. Bharwada, Isaac V. Farr
  • Publication number: 20130190417
    Abstract: The disclosure provides anionic Gemini surfactants comprising at least two carbonyl moieties and at least two aliphatic moieties. In some aspects, at least two of the aliphatic moieties comprise at least seven carbon atoms and at least one pair of conjugated carbon-to-carbon double bonds. The anionic Gemini surfactants are polymerizable and may be used to prepare triply periodic multiply continuous lyotropic phase and polymers thereof that substantially retain triply periodic multiply continuous lyotropic phase structure.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 25, 2013
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Wisconsin Alumni Research Foundation
  • Publication number: 20130161014
    Abstract: An amine adduct is made by (1) forming an addition intermediate by heating a mixture comprising at least one diene and at least one unsaturated fatty acyl compound, and reacting the addition intermediate with a diamine to form the amine adduct, or by (2) reacting at least one unsaturated fatty acyl compound with at least one diamine to form an amine intermediate, and heating a mixture of the amidoamine intermediate and at least one diene to form the amine adduct, or by (3) reacting at least one unsaturated fatty tertiary amine compound with at least at least one diene to form the amine adduct.
    Type: Application
    Filed: December 21, 2012
    Publication date: June 27, 2013
    Applicant: RHODIA OPERATIONS
    Inventors: Derek Pakenham, Mikal Morvan, Guillaume Degre
  • Publication number: 20130109025
    Abstract: The present invention relates to the field of improving and stabilizing concentrated solutions and in particular to improving and stabilizing concentrated solutions for the extraction of nucleic acids from sample material. Thus, the present invention, further, relates to the field of molecular biology. The present invention describes the use of betaines for stabilizing organic salts or chaotropic agents in solution which is particularly useful in cases where organic salts or chaotropic agents are present at high concentration such as for example chaotropic agents in buffers for the extraction of nucleic acids from sample material. The present invention describes the corresponding buffers and further relates to processes for the extraction of nucleic acids from sample material as well as processes for the analysis of sample material. Moreover, the present invention relates to kits and cartridges comprising at least one container with the corresponding buffer.
    Type: Application
    Filed: May 27, 2011
    Publication date: May 2, 2013
    Inventors: Anke Pierik, Paul Offermans, Bernadet Meijering, Peter Sillekens, Henk Stapert
  • Patent number: 8415497
    Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: April 9, 2013
    Assignee: Novabay Pharmaceuticals, Inc.
    Inventors: Ramin Najafi, Rakesh K. Jain, Timothy P. Shiau, Eddy Low, Satheesh K. Nair
  • Publication number: 20130065325
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Application
    Filed: May 18, 2011
    Publication date: March 14, 2013
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Patent number: 8283106
    Abstract: Disclosed is a fluorinated sulfonic acid salt or fluorinated sulfonic acid group-containing compound having a structure represented by the following general formula (A). In the formula, n indicates an integer of 1 to 10; R indicates a substituted or unsubstituted C1-C20 linear, branched or cyclic alkyl group, a substituted or unsubstituted C1-C20 linear, branched or cyclic alkenyl group, a substituted or unsubstituted C6-C15 aryl group, or a C4-C15 heteroaryl group; and a indicates 1 or 0. A photoacid generator containing the above fluorinated sulfonic acid salt or fluorinated sulfonic acid group-containing compound shows high sensitivity to an ArF excimer laser or the like, presents no concerns about human body accumulation, can generate an acid (photoacid) of sufficiently high acidity, and exhibits high solubility in a resist solvent and good compatibility with a resist resin.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: October 9, 2012
    Assignee: Central Glass Company, Limited
    Inventors: Kazuhiko Maeda, Yoshimi Isono, Satoru Narizuka
  • Publication number: 20120253064
    Abstract: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provided a parakeratosis inhibitor, a pore reducing agent and a skin roughness preventing/ameliorating agent each comprising at least one compound selected from the group consisting of specified glycine derivatives and salts thereof and specified aminosulfuric acid derivatives and salts thereof. Still further, there are provided skin preparations for external use comprising these compounds.
    Type: Application
    Filed: May 9, 2012
    Publication date: October 4, 2012
    Applicant: SHISEIDO COMPANY, LTD.
    Inventors: Mikiko Kaminuma, Masaru Suetsugu, Toshii Iida, Shinji Inomata, Keiko Takada, Yuji Katsuta
  • Publication number: 20120190886
    Abstract: A composition for lowering a blood uric acid level is characterized by comprising taurine as an active ingredient.
    Type: Application
    Filed: September 10, 2010
    Publication date: July 26, 2012
    Applicant: TAISHO PHARMACEUTICAL CO., LTD.
    Inventors: Fuminori Kimura, Hideaki Kitajima, Takao Tanaka, Toru Nishikawa
  • Publication number: 20120132564
    Abstract: The present invention relates to a process for the removal of organic acids, particularly naphthenic acids, from crude oils and crude oil distillates by use of a supported basic ionic liquid in a mass ratio of crude oil and/or crude oil distillate and ionic liquid of from greater than 40:1, the basic ionic liquid comprises a basic anion selected from serinate, prolinate, histidinate, threoninate, valinate, asparaginate, taurinate and lysinate.
    Type: Application
    Filed: March 30, 2010
    Publication date: May 31, 2012
    Inventors: Chris Hardacre, Peter Goodrich, Kris Anderson
  • Publication number: 20120053243
    Abstract: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provide a parakeratosis inhibitor and a pore reducing agent each comprising at least one compound selected from the group consisting of a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid, a beta-alanine derivative and salts of these derivatives.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 1, 2012
    Applicant: SHISEIDO COMPANY, LTD.
    Inventors: Mikiko Kaminuma, Masaru Suetsugu, Toshii Iida, Shinji Inomata, Keiko Takada, Yuji Katsuta
  • Publication number: 20110313040
    Abstract: The invention relates to organic nutrient salts, to compositions containing the same, to their preparation as well as their use. Preferred compositions include nutraceutical compositions and dietary supplements for use in neuroprotection and for improving or protecting cognitive and memory function.
    Type: Application
    Filed: November 13, 2009
    Publication date: December 22, 2011
    Applicant: BELLUS HEALTH INC.
    Inventors: Xianqi Kong, Nigel Levens, Serge Lamothe, Ahmed Aman
  • Publication number: 20110280815
    Abstract: The present invention provides a composition for inhibiting melanin production to promote skin whitening, which is characterized by containing compounds represented by formula (I): wherein R1, R2 and R3 are defined as herein. The present invention also provides a method for inhibiting melanin production to promote skin whitening by using the same.
    Type: Application
    Filed: August 13, 2010
    Publication date: November 17, 2011
    Applicant: TAIWAN HOPAX CHEMS. MFG. CO., LTD.
    Inventors: Han-Fen HUANG, Shan-Ying Lin
  • Patent number: 8044100
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 25, 2011
    Assignee: Bellus Health Inc.
    Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
  • Patent number: 7999009
    Abstract: Strontium salts of the sulphonic acids of formula (I): A-B—SO3H??(I), wherein: A represents a group selected from OH, NH2, SO3H and CO2H, B represents an arylene group or an optionally substituted linear or branched C1-C12alkylene chain wherein one or more carbon atoms of the alkylene chain may be optionally replaced by an oxygen atom, by a nitrogen atom or by an SO2 group. Medicinal products containing the same which are useful in the treatment of osteoarthritis and osteoporosis.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: August 16, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Francois Lefoulon, Yves Rolland
  • Patent number: 7972633
    Abstract: Compositions for supporting healthy memory and optimizing mental energy and methods for improving, preventing, and treating mental disorders or deterioration. The compositions of the invention can be formulated as nutritional or dietary supplements.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: July 5, 2011
    Assignee: Applied Cognitive Sciences, LLC
    Inventor: Kyl L. Smith
  • Publication number: 20110152537
    Abstract: The present invention relates to chemical compounds comprising a [Y(CHRa)n—CH(Ra)SO3]? anion, their preparation and application. The chemical compounds are preferably ionic liquids.
    Type: Application
    Filed: May 12, 2009
    Publication date: June 23, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Peter Wasserscheid, Natalia Paape, Andreas Boesmann, Peter Schulz
  • Publication number: 20110151025
    Abstract: Disclosed herein are methods and compositions for the treatment or prophylaxis, in a mammal, of bronchopulmonary infections, obstructive pulmonary disease, cystic fibrosis, and ventilator-associated infections. The methods and compositions include a therapeutically effective amount of one or more N-halogenated or N,N-dihalogenated amines, and their analogues, derivatives, or pharmaceutically acceptable salts and esters.
    Type: Application
    Filed: April 10, 2009
    Publication date: June 23, 2011
    Inventors: Waldemar Gottardi, Markus Nagl, Ramin Najafi, Lu Wang, Rakesh K. Jain, Timothy Shiau, Eddy Low, Charles Francavilla
  • Publication number: 20110091570
    Abstract: Disclosed herein are compositions, methods, uses, and devices having antiseptic and anticoagulation properties in a mammal. The compositions, methods, uses, and devices are based on a therapeutically effective amount of one or more N-halogenated or N,N-dihalogenated amines, analogues or derivatives thereof, or pharmaceutically acceptable salts and esters. The preferred compound is N-chlorotaurine.
    Type: Application
    Filed: March 17, 2009
    Publication date: April 21, 2011
    Inventor: Waldemar Gottardi
  • Publication number: 20110071116
    Abstract: The present invention relates to a formulation comprising a N-halogenated amino acid and a phase transfer agent. The present invention also describes a method for disinfecting and/or cleaning a contact lens comprising contacting a contact lens with a formulation comprising a N-halogenated amino acid salt for a time sufficient to disinfect and/or clean the lens.
    Type: Application
    Filed: November 24, 2010
    Publication date: March 24, 2011
    Applicant: ALCON RESEARCH, LTD.
    Inventors: L. Wayne Schneider, Wesley Wehsin Han, Masood A. Chowhan, David W. Stroman, W. Dennis Dean, Michael S. Gaines
  • Publication number: 20110052813
    Abstract: A functionalised graphene oxide and a method of making a functionalised graphene oxide comprising: (i) oxidizing graphite to form graphite oxide wherein the graphene sheets which make up the graphite independently of each other have a basal plane fraction of carbon atoms in the sp2-hybridised state between 0.1 and 0.9, wherein the remainder fraction comprises sp3-hybridised carbon atoms which are bonded to oxygen groups selected from hydroxyl and/or epoxy and/or carboxylic acid; and (ii) exfoliating and in-situ functionalizing the graphite oxide surface with one or more functional groups such that functionalisation of the surface is effected at a concentration greater than one functional group per 100 carbon atoms and less than one functional group per six carbon atoms. The functionalised graphene oxide is dispersible at high concentrations in appropriate solvents without aggregating or precipitating over extended periods at room temperature.
    Type: Application
    Filed: January 3, 2009
    Publication date: March 3, 2011
    Inventors: Peter Ho, Lay-Lay Chua, Shuai Wang, Perq-Jon Chia, Ghim Siong Goh
  • Patent number: 7893109
    Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: February 22, 2011
    Assignee: Novabay Pharmaceuticals, Inc.
    Inventors: Mansour Bassiri, Ramin Najafi, Lu Wang, Jane Yang
  • Patent number: 7858820
    Abstract: Described herein are both non-hygroscopic salts of L-carnitine and alkanoyl L-carnitine with taurine chloride (2-aminoethane-sulphonic chloride) and non-hygroscopic salts of L-carnitine and alkanoyl L-carnitine with glycine chloride which lend themselves favorably to the preparation of solid compositions suitable for oral administration. Also described are solid compositions containing said salts.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: December 28, 2010
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Maria Ornella Tinti
  • Publication number: 20100311791
    Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.
    Type: Application
    Filed: December 28, 2007
    Publication date: December 9, 2010
    Inventors: Ramin Najafi, Rakesh K. Jain, Timothy P. Shiau, Eddy Low, Satheesh K. Nair
  • Patent number: 7846971
    Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds. FIG. 1: A dual chamber apparatus for the preparation of NNDCT on site.
    Type: Grant
    Filed: January 25, 2006
    Date of Patent: December 7, 2010
    Assignee: Novabay Pharmaceuticals, Inc.
    Inventors: Ramin Najafi, Mansour Bassiri, Lu Wang, Behzad Khosrovi
  • Patent number: 7799762
    Abstract: The present invention is directed in particular to dipeptide-like compounds derived from functionally substituted amino acids, having fatty acid chains bound thereto through amidification of the amine functional groups of said dipeptide-like compounds, one end portion of which bears an accessory functional side chain spacer, with the other end portion being an acid group either in neutral or charged state. Compounds of the present invention have immunomodulating properties like adjuvants, In addition, compounds of the invention can be grafted on a given antigen in order to modulate or tune the immune response or can be equally grafted on a pharmaceutical carrier to enhance the therapeutic effect or targeting thereof. Accordingly, compounds of the invention find use in human and veterinary medicine both as immunogens and diagnostic tools.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: September 21, 2010
    Assignee: OM Pharma
    Inventors: Jacques Bauer, Olivier Richard Martin, Sylvain Rodriguez
  • Publication number: 20100150804
    Abstract: One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines, aryl amines or tertiary amines. The TSILs may be used for gas capture, capitalizing on their non-volatile nature. In certain embodiments, the captured gas is selected from the group consisting of CO2, SO2, CS2, and NO2. Another aspect of the present invention relates to a library of CO2-philic salts, which library facilitates reactive gas separation. In certain embodiments, the CO2-philic salts are CO2-reactive TSILs. In certain embodiments, the CO2-philic salts are resinous or plastic in nature.
    Type: Application
    Filed: April 2, 2008
    Publication date: June 17, 2010
    Applicant: University of South Alabama
    Inventor: James H. Davis, JR.
  • Publication number: 20100069290
    Abstract: The ejection liquid of the present invention includes a compound having a guanidine group, and a carboxyl group or a sulfonic acid group in one molecule, and being represented by the general formula (1), or a salt of the compound, for the purpose of stably ejecting a solution including at least one of a protein and a peptide by imparting thermal energy to the solution.
    Type: Application
    Filed: November 9, 2007
    Publication date: March 18, 2010
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Yohei Masada, Masaru Sugita, Hideki Kaneko, Naoko Sakurada
  • Publication number: 20090318556
    Abstract: Disclosed herein are biomarkers for determining gamma radiation exposure by an animal or human. The biomarkers include 3-hydroxy-2-methylbenzoic acid 3-O-sulfate, N-hexanoylglycine, ?-thymidine, taurine, xanthine, xanthosine, 2?-deoxyuridine, 2?-deoxycytidine, 2?-deoxyxanthosine, or any salt, ion, or combination thereof. Also disclosed are methods for determining gamma radiation exposure by an animal or human, which include the step of measuring the amount of one or more biomarkers specific to gamma radiation in the biological fluid and correlating the amount of said biomarkers to the amount of gamma radiation exposure by the animal or human. Systems for determining gamma radiation exposure by an animal or human and methods of treating an animal or human for gamma radiation exposure are also disclosed.
    Type: Application
    Filed: May 15, 2008
    Publication date: December 24, 2009
    Inventors: Jeffrey R. Idle, Frank J. Gonzalez, John B. Tyburski, Kristopher W. Krausz, Andrew David Patterson
  • Publication number: 20090308248
    Abstract: An acid gas absorbent comprising a metal sulfonate, phosphonate or carboxylate of a hindered amine and a process for the selective removal Of H2S as well as other acidic components such as carbon disulfide, carbonyl sulfide and oxygen and sulfur derivatives of C1 to C4 hydrocarbons from mixtures containing such acidic components and CO2 using said absorbent.
    Type: Application
    Filed: August 1, 2006
    Publication date: December 17, 2009
    Inventors: Michael Siskin, Alan R. Katritzky, Frank Cheng-Yu Wang
  • Publication number: 20090269673
    Abstract: The invention relates to a method for producing perfluoroalkanesulfonic acid esters and for further transforming the same into the salts thereof. The invention also relates to the use of the produced compounds in electrolytes, batteries, capacitors, supercapacitors, and galvanic cells.
    Type: Application
    Filed: July 8, 2009
    Publication date: October 29, 2009
    Inventors: Nikolai Ignatyev, Michael Schmidt, Udo Heider, Peter Sartori, Andry Kucheryna
  • Publication number: 20090163606
    Abstract: Suspensions having additives for controlled dispersion including a solvent, an ion source, a particle source selected from a partially dissolving colloid or a non-dissolving colloid, and an additive where the additive is added to the solvent prior to the ion source and the particle source when the particle source is the partially dissolving colloid.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 25, 2009
    Inventors: GLEN HAROLD KIRBY, Brett Allen Boutwell