Nitrogen In The Acyclic Chain Patents (Class 562/43)
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Patent number: 8969616Abstract: A process for the preparation of isosulfan blue (Active Pharmaceutical Ingredient) is provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). Also provided is a process for the preparation of an isoleuco acid of formula (4), which upon mild oxidation gives rise to isosulfan blue of pharmaceutical grade which can be used for preparation of pharmaceutical formulations. The isolation and purification procedures provided in the process provide substantially pure isosulfan blue with HPLC purity 99.5% or greater.Type: GrantFiled: July 25, 2013Date of Patent: March 3, 2015Assignee: Apicore US LLCInventors: Ravishanker Kovi, Satyam S. Nampalli, Peter Xavier Tharial
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Publication number: 20140329746Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.Type: ApplicationFiled: July 16, 2014Publication date: November 6, 2014Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
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Patent number: 8710236Abstract: The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity. The present invention further provides for pharmaceutical compositions comprising the same as well as methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucagon receptor antagonist is indicated, including Type I and II diabetes, insulin resistance and hyperglycemia. The present invention also provides for processes of making the compounds of Formula I, including salts and co-crystals thereof, and pharmaceutical compositions comprising the same.Type: GrantFiled: April 8, 2011Date of Patent: April 29, 2014Assignee: Metabasis Therapeutics, Inc.Inventors: Jorge E. Gomez-Galeno, K. Raja Reddy, Paul D. van Poelje, Robert Huerta Lemus, Thanh Huu Nguyen, Matthew P. Grote, Qun Dang, Scott J. Hecker, Venkat Reddy Mali, Mingwei Chen, Zhili Sun, Serge Henri Boyer, Haiqing Li, William Craigo
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Publication number: 20140113842Abstract: Betaine surfactants of formula (I) and preparation methods and uses thereof are provided. The surfactant can decrease the interfacial surface tension of crude oil till 10?3 mN/m, have the capabilities of antiheating (130° C.), antimineralizing and antidiluting, and can be used in the field of tertiary oil recovery.Type: ApplicationFiled: March 11, 2011Publication date: April 24, 2014Applicant: PetroChina Company LimitedInventors: Chunde Liu, Shiyi Yuan, Demin Wang, Xinmin Song
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Publication number: 20140107027Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.Type: ApplicationFiled: December 18, 2013Publication date: April 17, 2014Applicant: BHI LIMITED PARTNERSHIPInventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
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Patent number: 8609864Abstract: The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.Type: GrantFiled: January 7, 2010Date of Patent: December 17, 2013Assignee: Purdue Pharmaceutical Products, L.P.Inventors: Yu Chen, Yi Chen
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Publication number: 20120172589Abstract: Process for the synthesis of ivabradine of formula (I): and addition salts thereof with a pharmaceutically acceptable acid.Type: ApplicationFiled: September 17, 2010Publication date: July 5, 2012Applicant: LES LABORATOIRES SERVIERInventors: Jean-Louis Peglion, Pascal Caignard, Jean-Michel Lerestif, Jean-Pierre Lecouve
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Publication number: 20110269706Abstract: The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.Type: ApplicationFiled: January 7, 2010Publication date: November 3, 2011Applicant: Northlake Biosciences LLCInventors: Yu Chen, Yi Chen
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Publication number: 20110110842Abstract: Systems and methods for the extraction of carbon nanotubes (CNTs) by continuous and/or batch processing are disclosed. Generally, a carbon nanotube material including carbon nanotubes (CNTs), carbon nanoparticles (CNPs), and carboxylated carbon (CC) is provided and agitated to produce a well-dispersed mixture. The well-dispersed mixture can be allowed to stand in a vessel having a lower end and an upper end. In some cases, the CNPs settle at the lower end. In some cases, at least some of the CNTs and CC are disposed at the upper end and can be removed in a dispersion, which can be pH adjusted and/or filtered to extract the CNTs from the CC.Type: ApplicationFiled: December 15, 2010Publication date: May 12, 2011Inventor: Robert C. Haddon
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Publication number: 20100316557Abstract: Systems and methods for the purification of carbon nanotubes (CNTs) by continuous liquid extraction are disclosed. Carbon nanotubes are introduced to a flow of liquid that enables the separation of CNTs from impurities due to differences in the dispersibility of the CNTs and the impurities within the liquid. Examples of such impurities may include amorphous carbon, graphitic nanoparticles, and metal containing nanoparticles. The continuous extraction process may be performed in one or more stages, where one or more of extraction parameters may be varied between the stages of the continuous extraction process in order to effect removal of selected impurities from the CNTs. The extraction parameters may include, but are not limited to, the extraction liquid, the flow rate of the extraction liquid, the agitation of the liquid, and the pH of the liquid, and may be varied, depending on the impurity to be removed from the CNTs.Type: ApplicationFiled: June 10, 2010Publication date: December 16, 2010Applicant: Carbon Solutions, Inc.Inventor: Robert C. Haddon
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Patent number: 7767846Abstract: A novel class of compounds that includes HPTS-Cys-MA, and methods of making them are disclosed herein. The class of compounds including HPTS-Cys-MA are useful as fluorescent dyes for analyte detection.Type: GrantFiled: August 22, 2008Date of Patent: August 3, 2010Assignee: Glumetrics, Inc.Inventor: Jeff T Suri
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Patent number: 7417164Abstract: A novel class of compounds that includes HPTS-Cys-MA, and methods of making them are disclosed herein. The class of compounds including HPTS-Cys-MA are useful as fluorescent dyes for analyte detection.Type: GrantFiled: July 24, 2007Date of Patent: August 26, 2008Assignee: Glumetrics Inc.Inventor: Jeff T. Suri
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Patent number: 7414076Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.Type: GrantFiled: June 18, 2004Date of Patent: August 19, 2008Assignee: Neurochem (INTERNATIONAL) LimitedInventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
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Patent number: 7399577Abstract: Compounds of the formula (I) or (II) wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2- C10haloalkanoyl, halobenzoyl; R2 is halogen or C1-C10 haloalkyl; Arl is phenyl, biphenylyl, fluorenyl, naphthyl, anthracyl, phenanthryl, or heteroaryl, all of which are optionally substituted; Ar?1 is for example phenylene, naphthylene, diphonylene, heteroarylene, oxydiphenylene, phenyleneD-D1-D-phenylene or —Ar?1-A1—Y1-A1—Ar?1—; wherein these radicals optionally are substituted; Ae?, is phenylene, naphthylene, anthracylene, phenanthrylene, or heteroarylene, all optionally substituted; A, is for example a direct bond, —0—, —S—, or —NR6—; Y, inter alia is C1-C18alkylene; X is halogen; D is for example —0—, —S— or —NR6—; D, inter alia is C1-C18alkylene; are particularly suitable as photolatent acids in ArF resist technology.Type: GrantFiled: February 9, 2004Date of Patent: July 15, 2008Assignee: Ciba Specialty Chemicals CorporationInventors: Hitoshi Yamato, Toshikage Asakura, Akira Matsumoto, Peter Murer, Tobias Hintermann
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Patent number: 7244764Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.Type: GrantFiled: June 18, 2004Date of Patent: July 17, 2007Assignee: Neurochem (International) LimitedInventors: Xianqi Kong, Walter A. Szarek, Francine Gervais
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Patent number: 6943268Abstract: The invention provides anti-thiol reagents which inhibit enzyme activity of cell-associated protein disulfide isomerase (PDI) by oxidizing or blocking PDI active site vicinal thiol groups which normally participate in disulfide bond rearrangement of PDI substrates. Inhibition of this PDI function is particularly useful in blocking PDI-mediated entry of HIV or other virions into a host cell, as well as inhibiting lymphocyte traffic through the lymph nodes. The invention further provides an assay for the identification of such PDI inhibitors based on the discovery that inhibitors of the invention also induce shedding of the leucocyte L-selectin adhesion molecule. The invention additionally provides for suppression of inflammation and of lymph node entry by calmodulin antagonists that, like PDI inhibition, cause leukocyte L-selectin shedding.Type: GrantFiled: October 31, 2002Date of Patent: September 13, 2005Assignee: Science & Technology Corporation @ UNMInventors: Snezna Rogelj, Teresa A. Bennett, Larry A. Sklar
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Publication number: 20040044208Abstract: This invention relates to high purity hydrogen ion buffers and in particular amino-organosulfonic acid zwitterionic compositions having low metal content. The concentration of any single metal in the composition is no greater than about 500 ppb, and ideally is less than about 20 ppb.Type: ApplicationFiled: August 29, 2002Publication date: March 4, 2004Applicant: Buffers & Biochemicals CorporationInventors: David Bow, Glenn Thomas Carroll
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Patent number: 6531628Abstract: Substantive UV-absorbing water-soluble 2-hydroxy sulfobetaine of cinnamidoalkylamines of Formula I. Hair, skin and fabric care compositions containing the compounds of Formula I. wherein, R1 is a substituent, selected from H, halo, —OH, —NH2, —NO2, —OCH3, —N(CH3)2, alkyl groups containing from 1 to 6 carbon atoms, alkoxy groups containing from 1 to 6 carbon atoms, alkylamino or N,N-dialkylamino groups containing from 1 to 6 carbon atoms; R2 is selected from hydrogen, alkyl group containing from 1 to 12 carbon atoms; R3 and R4 are independently selected from benzyl, alkyl group containing from 1 to 12 carbon atoms, n is an integer from 1 to 6.Type: GrantFiled: March 22, 2002Date of Patent: March 11, 2003Assignee: Galaxy Surfactants Ltd.Inventors: Nirmal Madhukar Koshti, Arun Harchandra Jawale, Bharat Bhikaji Parab, Shubhangi Dattaram Naik, Manasi Dattatraya Moghe, Tanaji Shamrao Jadhav, Subhash Shivling Nashte
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Publication number: 20020147354Abstract: This invention provides a new class of squaraine dyes having moieties which serve for the covalent attachment to biological substrates and resulting in the fluorescent labeling of the substrates. The labeled substrates are intended for use in analytical techniques for the detection and measurement of biological and clinical compounds of interest.Type: ApplicationFiled: April 2, 2001Publication date: October 10, 2002Inventor: Spyros Theodoropulos
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Publication number: 20020095050Abstract: The present invention relates to new phenylserine derivatives as integrin antagonists with a broad spectrum of action having, inter alia, antiosteoporotic, antirestenotic, anticarcinogenic and antiatherosclerotic activity. The present invention moreover relates to the preparation of these compounds and their use for the production of medicaments, and also medicaments comprising them.Type: ApplicationFiled: June 12, 2001Publication date: July 18, 2002Inventor: Andrea Vaupel
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Patent number: 6153789Abstract: The present invention provides a method of purifying an aqueous dye solution having an aldehyde and/or ketone impurity including a step of reacting the impurity with a hydrazine derivative, forming a water-insoluble hydrazone compound. The hydrazone compound is then removed from the solution to form a dye having an increased purity.Type: GrantFiled: June 29, 1999Date of Patent: November 28, 2000Assignee: BASF CorporationInventors: Kevin P. Cusack, Kwang Kim, Dennis L. Edie, Benjamin S. Tennyson
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Patent number: 6147253Abstract: N-protected/N-substituted alpha-amino aldehydes, which are useful as pharmaceuticals and pharmaceutical intermediates, can be stored and shipped in a more stable form as N-protected/N-substituted-beta-amino hydroxy sulfonates which can be readily converted back into the aldehyde under mild conditions. The present invention relates to N-protected/N-substituted-beta-amino hydroxy sulfonates and their preparation and use.Type: GrantFiled: August 16, 1999Date of Patent: November 14, 2000Assignee: G. D. Searle & Co.Inventor: Joseph J. Wieczorek
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Patent number: 6011140Abstract: Reactive dyes of the formula ##STR1## where n is 1 or 2,G.sup.1 is hydrogen or hydroxyl,G.sup.2 is hydrogen or hydroxysulfonyl,G.sup.3 is hydrogen or arylazo,R.sup.1 is hydrogen or hydroxysulfonylmethyl,R.sup.2 is hydrogen or hydroxysulfonylmethyl, andD is the radical of a diazo or tetraazo component having in each case at least one anchor radical of the formula SO.sub.2 --Y, where Y is vinyl or substituted ethyl,their use for dyeing or printing hydroxyl-containing or nitrogenous organic substrates, and naphthylamines as intermediates therefor.Type: GrantFiled: July 6, 1998Date of Patent: January 4, 2000Assignee: BASF AktiengesellschaftInventors: Andrea Zamponi, Manfred Patsch, Hermann Loffler
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Patent number: 5948939Abstract: An .omega.-guanidino-.alpha.-amino-acid (or its functional derivative) or a compound containing it may be prepared by the reaction of the .omega.-amino group of an .alpha.,.omega.-diamino acid (or its functional derivative) or a compound containing it with a formamidinesulfonic acid.Type: GrantFiled: April 20, 1992Date of Patent: September 7, 1999Assignee: Syntex (U.S.A.) Inc.Inventors: Humberto B. Arzeno, David J. Morgans, Jr.
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Patent number: 5847201Abstract: N-protected/N-substituted alpha-amino aldehydes, which are useful as pharmaceuticals and pharmaceutical intermediates, can be stored and shipped in a more stable form as N-protected/N-substituted-beta-amino hydroxy sulfonates which can be readily converted back into the aldehyde under mild conditions. The present invention relates to N-protected/N-substituted-beta-amino hydroxy sulfonates and their preparation and use.Type: GrantFiled: November 13, 1996Date of Patent: December 8, 1998Assignee: G.D. Searle & Co.Inventor: Joseph J. Wieczorek
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Patent number: 5817861Abstract: A process for the preparation of (S)-N,N'-bis?2-hydroxy-1-(hydroxymethyl)ethyl!-5-(2-acetoxy-propionylamino )-2,4,6-triiodo-isophthalamide, an intermediate useful for the synthesis of iopamidol, by reaction between L-5-(2-acetoxy-propionylamino)-2,4,6-triiiodoisophthaloyl dichloride and 2-amino-1 ,3-propanediol in N-methylpyrrolidone and in the presence of a base, is described.Type: GrantFiled: March 21, 1997Date of Patent: October 6, 1998Assignee: Bracco International BVInventors: Marco Villa, Antonio Nardi, Maurizio Paiocchi
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Patent number: 5789557Abstract: Reactive dyes of the formula ##STR1## where n is 1 or 2,R.sup.1 is hydrogen or hydroxysulfonyl,R.sup.2 is hydrogen or hydroxyl,R.sup.3 is substituted C.sub.1 -C.sub.4 -alkyl, C.sub.5 -C.sub.7 -cycloalkyl or substituted phenyl,R.sup.4 is hydrogen or R.sup.3 and R.sup.4, together with the nitrogen atom linking them, form a heterocyclic radical andD is a radical of a diazo or tetrazo component, each having at least one mechanism,their use for dyeing or printing hydroxyl-containing or nitrogen-containing organic substrates, and novel aminonaphthalenes.Type: GrantFiled: March 27, 1997Date of Patent: August 4, 1998Assignee: Basf AktiengesellschaftInventors: Jurgen Dornhagen, Heike Kilburg, Manfred Patsch, Hermann Loffler, Ortwin Schaffer
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Patent number: 5763610Abstract: A composition comprising a nitrogen-containing olefinic compound and a process for using the nitrogen-containing olefinic compound to produce a water-soluble polymer which has applications in a subterranean formation are provided. The nitrogen-containing olefinic compound can be made from an amine and an alkylating agent. The polymer produced can be used in drilling fluids, workover fluids, completion fluids, permeability corrections, water or gas coning prevention, fluid loss prevention, matrix acidizing, fracture acidizing, and combinations of any two or more thereof.Type: GrantFiled: February 21, 1997Date of Patent: June 9, 1998Assignee: Phillips Petroleum CompanyInventors: Iqbal Ahmed, Ahmad Moradi-Araghi, Odd Ivar Eriksen
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Patent number: 5686492Abstract: Described herein are disubstituted p-fluorobenzenesulfonamides, containing a CF.sub.3 group, of general formula I ##STR1## which are suitable as NMR diagnostic agents.Type: GrantFiled: June 6, 1995Date of Patent: November 11, 1997Assignee: Schering AktiengesellschaftInventors: Ulrich Niedballa, Johannes Platzek, Bernd Raduchel
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Patent number: 5326906Abstract: The ampholytes are extracted from the reaction solution with a liquid cation exchanger which is immiscible with the acidic aqueous reaction solution, where the cation exchanger is dissolved in at least one organic solvent which is immiscible with water and forms an organic phase with the organic solvent. Subsequently the organic phase which is loaded with the ampholyte is separated from the reaction solution, and then the ampholytes are back-extracted from the organic phase with aqueous solvents. The product losses in the process are low, and the residual salt content is very low.Type: GrantFiled: January 10, 1992Date of Patent: July 5, 1994Assignee: Hoechst AktiengesellschaftInventors: Heribert Tetzlaff, Matthias Krull, Gernot Kremer, Christoph Porz
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Patent number: 5264622Abstract: Novel water-soluble methylenebis(dialkylaniline) derivatives of the following general formula and salts thereof are disclosed. They are useful as dye-forming substances in quantitative determination of peroxides in the copresence of peroxidase or the like. ##STR1## In the formula, R.sub.1 is hydrogen or a substituent selected from lower alkyl and C.sub.2-3 sulfoalkyl or hydroxysulfoalkyl; R.sub.2 is C.sub.2-3 sulfoalkyl or hydroxysulfoalkyl; and R.sub.3 is lower alkyl.Type: GrantFiled: December 21, 1992Date of Patent: November 23, 1993Assignee: Dojindo LaboratoriesInventor: Makoto Mizoguchi
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Patent number: 5153357Abstract: A process for the preparation of 2-(hydrogen, halogen or lower alkyl)-3-(hydroxy, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, --OCH.sub.2 CH.sub.2 OCH.sub.3, --OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5, --OCH.sub.2 CH.sub.2 SCH.sub.3 or --OCH.sub.2 CH.sub.2 SC.sub.2 H.sub.5)-4-(alkylthio or alkylsulfonyl)-acetophenones.Type: GrantFiled: December 17, 1991Date of Patent: October 6, 1992Assignee: Imperical Chemical Industries PLCInventor: Richard W. Brown
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Patent number: 5120872Abstract: A compound of the formula ##STR1## in which R.sub.1 and R.sub.2 independently of one another are each C.sub.1 -C.sub.10 alkyl which is unsubstituted or substituted by hydroxyl, C.sub.1 -C.sub.4 alkoxy, phenyl, sulfo, sulfato, thiosulfato, cyano or halogen, C.sub.5 -C.sub.7 cycloalkyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 alkoxy, or phenyl or naphthyl which both are unsubstituted or substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.4 alkanoylamino, benzoylamino, halogen or sulfo, R.sub.3 is hydrogen, halogen, C.sub.1 -C.sub.10 alkyl which is unsubstituted or substituted by hydroxyl, C.sub.1 -C.sub.4 alkoxy, phenyl, sulfo, sulfato, thiosulfato, cyano or halogen, C.sub.1 -C.sub.10 alkoxy which is unsubstituted or substituted by C.sub.1 -C.sub.4 alkoxy, or phenoxy which is unsubstituted or substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.Type: GrantFiled: December 3, 1990Date of Patent: June 9, 1992Assignee: Ciba-Geigy CorporationInventors: Harald Walter, Rudolf Hurter
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Patent number: 5110985Abstract: A process for preparing a carboxyalkyl-substituted hydroxylamine represented by formula (I) ##STR1## where L represents an alkylene group; A represents a hydrogen atom, a sulfo group, a carboxy group, a phosphono group, a trialkylammonio group, a hydroxy group, an amino group, an acyl group, a carbamoyl group, a sulfamoyl group, an alkoxycarbonyl group, or a cyano group; and R.sub.1, R.sub.2, and R.sub.3, which may be the same or different, each represent a hydrogen atom, an alkyl group, or an aryl group; which comprises: reacting an .alpha.,.beta.-unsaturated carboxylic acid represented by formula (II) as an alkylating agent ##STR2## where R'.sub.1, R'.sub.2, and R'.sub.3, which may be the same or different, each represent the same group as defined for R.sub.1, R.sub.2, and R.sub.Type: GrantFiled: November 9, 1990Date of Patent: May 5, 1992Assignee: Fuji Photo Film Co., Ltd.Inventors: Hiroshi Hayakawa, Kiyoshi Morimoto
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Patent number: 5026905Abstract: The present invention describes a class of dyes for use in staining cell samples and methods of making such dyes. A preferred class of dyes known as detergent dyes which possess the ability to stain cells in whole blood and are only slowly leached or lost from the stained cells over time are described. The present invention has application, for example, to blood typing for the determination of the presence of blood group antigens A, B, AB, O, and D (Rh.sub.o) and antibodies to such antigens.Type: GrantFiled: August 19, 1988Date of Patent: June 25, 1991Assignee: Syntex (U.S.A.) Inc.Inventors: Thomas L. Tarnowski, Mae W. Hu, Maureen Laney, John S. Pease, Vartan Ghazarossian
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Patent number: 4985595Abstract: Aminobenzamide derivatives of the formula (I) ##STR1## wherein: R.sub.1 and R.sub.2 each represents a lower alkoxy group,R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower acyl group, a lower alkoxycarbonyl group or --R.sub.5 --SO.sub.3 Z, wherein R.sub.5 represents a lower alkylene group and Z represents an alkali metal or an alkaline earth metal,R.sub.4 represents an amino group, a morpholino group or a lower alkylamino group which may be substituted with a hydroxyl group at the alkyl moiety thereof, with the proviso that, when R.sub.3 represents a hydrogen atom, R.sub.4 cannot be an amino group,Y represents a hydrogen atom, a halogen atom or a lower alkoxy group,n represents an integer of from 1 to 6,and salts thereof; are disclosed. These compounds have excellent anti-peptic ulcer activities, and chemical and physical stabilities.Type: GrantFiled: December 1, 1988Date of Patent: January 15, 1991Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Tosaku Miki, Masahide Asano, Toru Hosokami
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Patent number: 4978781Abstract: The present invention relates to low-foam alkali-stable surface active agents which are amphoteric. The subject materials are hydroxypropyl sultaines.Type: GrantFiled: September 25, 1989Date of Patent: December 18, 1990Assignee: Miranol, Inc.Inventor: Richard J. Nadolsky
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Patent number: 4898944Abstract: Precursors for the preparation of fiber-reactive triphendioxazine dyestuffs correspond to the general formulas: ##STR1## in which Y' is a vinyl, a beta-hydroxyethyl or an ethyl group which contains in the beta-position a substituent which can be eliminated by an alkali;T is an optionally substituted alkyl (e.g.Type: GrantFiled: October 27, 1988Date of Patent: February 6, 1990Assignee: Hoechst AktiengesellschaftInventors: Gunther Schwaiger, Hartmut Springer, Walter Helmling
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Patent number: 4891159Abstract: Novel surface active agents of the formula: ##STR1## wherein R is selected from the group consisting of alkyl, aryl, alkylaryl groups of 2-18 carbons and alkoxymethyl wherein the alkoxy group is of 2-18 carbon atoms,R.sup.2 and R.sup.3 are individually selected from the group consisting of methyl; alkyl of 2 to 6 carbon atoms wherein said alkyl group is substituted by an electron-donating group on the beta carbon atoms thereof; polyoxyethylene and polyoxypropylene or R.sup.2 R.sup.3 may jointly form a --CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 -- or CH.sub.2 CH.sub.2 SCH.sub.2 CH.sub.2 -- group so as to form, together with the nitrogen atom to which they are bound, to form a morpholine or thiomorpholine ringQ is a covalent bond or ##STR2## wherein R.sup.1 is independently selected from the same groups as R.sup.2 and R.sup.Type: GrantFiled: August 27, 1986Date of Patent: January 2, 1990Assignee: Miranol Inc.Inventor: Richard J. Nadolsky