Abstract: A composition containing a compound represented by General Formula (I) below (see the definition in the specification for the symbols in the formula) or a salt thereof has an excellent CaSR agonistic effect and provides a pharmaceutical agent, a CaSR agonistic agent, a prophylactic or therapeutic agent for a disease that can be ameliorated through CaSR activation as well as seasonings and an agent for imparting kokumi.

Abstract: The invention provides novel compounds of the formula I below: wherein the meaning of each substituent is defined in the application. The compounds are useful as inhibitors of the glycine transporter and useful in the treatment of diseases responsive to the inhibition of the glycine transporter. The invention provides a pharmaceutical composition comprising a compound of Formula I as defined above and the use of compounds as above for the manufacture of medicaments for treatment of diseases responsive to ligands of the glycine transporter.

Abstract: The preferred oligomers of the present invention are polyureas having a number average molecular weight of <10,000. These oligomers are water-soluble, have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geometry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. These oligomers are prepared by reacting an aromatic diamine with a difunctional electrophile, in the presence of an acid acceptor, in water as the solvent or water with up to about 1 mole of water immiscible cosolvent, at a temperature of from 0.degree. to 100.degree. C. and at a pH between about 7 to about 9. The oligomers are useful for the treatment and/or diagnosis of AIDS and ARC.

Abstract: This invention relates to the novel pharmaceutical compositions of Formulas (I) and (II) each of which comprises a compound of Formula (I) or (II) and a pharmaceutically acceptable diluent or carrier.This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a compound or composition of Formula (I) or (II).

Abstract: There are described formazan dyes of the formula ##STR1## where m and n are each 1 or 2,Kat is the equivalent of a cation,Me is copper or nickel,X is oxygen or a radical of the formula CO-O or SO.sub.2 -O,Y is vinyl or a radical of the formula C.sub.2 H.sub.4 -Q, wherein Q is a group that is detachable under alkaline reaction conditions,E is a fiber-reactive radical,the rings A and B may be substituted and benzofused, andthe ring C may be substituted,the use thereof for dyeing or printing hydroxyl- or nitrogen-containing organic substrates, novel aminophenols and a process for preparing same.

Abstract: Sulfonic acid stilbenes are disclosed which block the infection of cells by HSV, HIV and CMV.

Abstract: Novel semicarbazides of the formula ##STR1## wherein R.sub.1 and R.sub.2, each independently of the other, are hydrogen, C.sub.1 -C.sub.5 alkyl, C.sub.2 -C.sub.5 alkenyl, C.sub.1 -C.sub.5 alkoxy or phenyl, or R.sub.1 and R.sub.2, together with the linking nitrogen atom, form a morpholine or piperazine radical, p is 0 or 1, and Q depends on the value of p as described herein. The novel compounds, which are water-soluble in aqueous application systems, have fibre affinity and are suitable for the photochemical and thermal stabilization of polyamide fibre materials and the dyeings produced thereon.

Abstract: There is disclosed a water-soluble, asymmetrical oxalic acid diarylamide of general formula ##STR1## wherein the substituents R.sub.1 are each independently of the other unsubstituted or hydroxy- or alkoxy-substituted C.sub.1 -C.sub.5 alkyl, unsubstituted or C.sub.1 -C.sub.5 alkyl-substituted benzyl,R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.12 alkyl or phenyl-C.sub.1 -C.sub.5 alkyl,R.sub.3 is hydrogen, halogen, C.sub.1 -C.sub.12 alkyl, phenyl-C.sub.1 -C.sub.5 alkyl or C.sub.1 -C.sub.5 alkoxy,A is a direct bond or a divalent radical of formula --O--Q--, whereinQ is unsubstituted or hydroxy-substituted C.sub.1 -C.sub.6 alkylene,M is hydrogen or alkali metal, andr is 2, 1 or 0.The novel water-soluble compound having fiber affinity is suitable for the photochemical and thermal stabilisation of polyamide fiber materials and the dyeings produced thereon.

Abstract: Urea derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently a 4-disubstituted aminoaryl group or the like, and R.sup.3 is a carboxyalkyl group or the like, is soluble in water and effective as a color producing reagent for determining hydrogen peroxide or the like or the activity of peroxidase.

Abstract: Urea derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently a 4-disubstituted aminoaryl group or the like, and R.sup.3 is a carboxyalkyl group or the like, is soluble in water and effective as a color producing reagent for determining hydrogen peroxide or the like or the activity of peroxidase.

Abstract: Compounds corresponding to Formula I ##STR1## wherein R.sup.1 denotes an acyl group andX denotes hydrogen, halogen, alkoxy, aroxy, SO.sub.3 H or a heterocyclic group attached through --O-- or --N<are prepared form a compound corresponding to Formula II ##STR2## wherein X has the meaning already indicated and Q denotes the group required for completing a dicarbonimide ringby reduction of the said compound to the amino compound and acylation into a compound corresponding to Formula III ##STR3## wherein X, Q and R.sup.1 have the meanings indicatedfollowed by conversion of the compound corresponding to Formula III into a compound corresponding to Formula I by hydrazinolytic or hydrolytic decomposition of the dicarbonimide ring.