Plural Rings Patents (Class 562/488)
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Patent number: 11161960Abstract: A method for rotary die cutting. The method may include providing, to an accumulator, an input comprising a melt. The method may include processing, by the accumulator utilizing a set of rolls, the melt to form a sheet of material. The method may include providing, from the accumulator, the sheet of material to a dandy roll. The method may include providing, from the dandy roll, the sheet of material to a rotary die. The method may include cutting, by the rotary die, a product from the sheet of material. The method may include providing, from the rotary die, the product to a stacker.Type: GrantFiled: February 25, 2021Date of Patent: November 2, 2021Assignee: OCTAL SAOC FZCInventors: Tarun Joshi, Muteeb Siddiqui, Klaus Haarmann, Jerry Bradnam, Sean Brown, Mohammed Razeem, William J. Barenberg, Nicholas P. Barakat
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Patent number: 10598658Abstract: A reduced graphene oxide-based biosensor includes a nano-structure field-effect transistor including a channel region which includes a reduced graphene oxide having a linking moiety to be bonded to a receptor specific to an analyte, and which is represented by a formula of —(C?O)—X—COOH, wherein X represents a C1-C3 alkenylene group or a C1-C3 alkylene group.Type: GrantFiled: November 16, 2015Date of Patent: March 24, 2020Assignee: Chang Gung UniversityInventors: Mu-Yi Hua, Hsiao-Chien Chen, Yi-Ting Chen, Rung-Ywan Tsai, Min-Cheng Chen, Chien-Lun Chen
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Patent number: 10029215Abstract: The present invention relates to a technology for manufacturing a nanocomposite membrane comprising a graphene oxide coating layer with a thickness of 1 nm to 50 nm, which is formed on various supports and has nanopores, and a reduced graphene oxide nanocomposite membrane, and applying the membranes to gas separation. The graphene oxide nanocomposite membrane for gas separation of the present invention has excellent gas permeability and selectivity at the same time, and especially, excellent hydrogen gas permeability and hydrogen gas selectivity compared with carbon dioxide, and the reduced graphene oxide nanocomposite membrane has remarkably enhanced hydrogen gas permeability and hydrogen gas selectivity compared with carbon dioxide, and thus the membranes are applicable as a gas separation membrane in an industrial field involving a hydrogen separation process.Type: GrantFiled: March 6, 2015Date of Patent: July 24, 2018Assignee: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)Inventors: Ho Bum Park, Hyo Won Kim, Myung Jin Yoo, Byung Min Yoo, Byungkook Ahn
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Patent number: 10016725Abstract: A forward osmosis process is provided, which includes separating a feed part and a draw solution part by a semi-permeable film. An ionic liquid is introduced into the draw solution part, and brine is introduced into the feed part. The brine has an osmotic pressure lower than that of the ionic liquid, so that pure water of the brine permeates through the semi-permeable film, enters the draw solution part, and mixes with the ionic liquid to form a draw solution. The draw solution was obtained out of the draw solution part to be left to stand at room temperature, so that the draw solution separated into a water layer and an ionic liquid layer.Type: GrantFiled: December 28, 2016Date of Patent: July 10, 2018Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Po-I Liu, Li-Ching Chung, Chih-Hsiang Fang, Chia-Hua Ho, Hsin Shao, Meng-Shun Huang, Ren-Yang Horng, Teh-Ming Liang, Min-Chao Chang, Tsui Jung Yang
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Patent number: 9738591Abstract: A compound for use as an antimicrobial having a formula (A).Type: GrantFiled: January 8, 2015Date of Patent: August 22, 2017Inventor: Ramiz Boulos
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Publication number: 20150135993Abstract: A method of treating particles by disaggregating, deagglomerating, exfoliating, cleaning, functionalising, doping, decorating and/or repairing said particles, in which the particles are subjected to plasma treatment in a treatment chamber containing a plurality of electrodes which project therein and wherein plasma is generated by said electrodes which are moved during the plasma treatment to agitate the particles.Type: ApplicationFiled: November 12, 2014Publication date: May 21, 2015Inventors: John Buckland, Dylan Walters
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Publication number: 20150126773Abstract: Synthetic alkylated graphenes of well chosen structure are prepared and used for mimicking indigenous asphaltenes. The mixtures can be used as multiphase flow test fluids in general and specifically in the Oil and gas industry.Type: ApplicationFiled: April 25, 2013Publication date: May 7, 2015Inventor: Vincent Olivier Pauchard
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Publication number: 20150065711Abstract: Disclosed are linear discrete PEG constructs, which can be created and produced in a precise and reproducible way. Key to being able to do these things, where x in the discrete PEGx can vary from about 2 to about 64, is that the processes used to make each linear portion is controlled to give essentially one oligomer/one compound. Having a variable length linear discrete PEG construct that is (a) primarily an linear discrete PEG construct with diagnostic or therapeutic groups attached along a chain of attachment cores, which is attached to a preferential locator; (b) is an m-discrete PEG as the terminal construct on the linear portion, and “hidden”; (c or linear discrete PEG with a terminus group that can be either negatively or positively charged, or neutral; and any of the discrete PEG portions can be designed to be cleaved after entering the cell.Type: ApplicationFiled: August 15, 2014Publication date: March 5, 2015Applicant: EquIP, LLCInventor: Paul D. Davis
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Patent number: 8969554Abstract: Disclosed are compounds exhibiting sufficient herbicidal activity at low application dosage when they are applied to soils and foliage, and an agrochemical composition using the same, in particular herbicides. The compounds are triazine derivatives represented by following Formula 1 or salts thereof, and the herbicides containing them: [Chem. 28] wherein in the formula, R1 represents a hydrogen atom; a C1-C12 alkyl group; a C2-C6 alkenyl group, etc., R2 represents a C1-C12 alkyl group, etc., Y and Z represent an oxygen atom or a sulfur atom, and A represents a 5- or 6-membered cyclic group which may contain a nitrogen atom, an oxygen atom, or a sulfur atom.Type: GrantFiled: May 26, 2011Date of Patent: March 3, 2015Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.Inventors: Atsushi Shibayama, Ryu Kajiki, Masami Kobayashi, Takashi Mitsunari, Atsushi Nagamatsu
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Publication number: 20140319404Abstract: The present invention relates to the use of certain substituted fullerenes in optoelectronic devices, preferably in photovoltaic cells, preferably in organic photovoltaic cells especially preferred in a two-component electron-selective buffer layer of an organic photovoltaic cell to improve the efficiency of solar cells for energy generation.Type: ApplicationFiled: July 3, 2012Publication date: October 30, 2014Applicant: LANXESS DEUTSCHLAND GMBHInventors: Roman Evgenievich Levin, Alexey Borisovich Kornev, Pavel Anatolyevich Troshin, Vladimir Fedorovich Razumov
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Publication number: 20140275605Abstract: A composition is described comprising a mixture of (methylcyclohexyl)toluene isomers having the following formula: wherein the mixture comprises at least 50 wt % in total of the 3,3, 3,4 4,3 and 4,4-isomers of (methylcyclohexyl)toluene.Type: ApplicationFiled: March 7, 2014Publication date: September 18, 2014Inventors: Jihad M. Dakka, Lorenzo C. DeCaul, Wei Tang
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Publication number: 20140163107Abstract: A pharmaceutical composition for treating viral infections by an influenza type A virus, includes a compound capable of acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of influenza type A viruses, and capable of binding to the viral-RNA-binding domain on the nucleoprotein. A pharmaceutical composition for treating viral infections by an orthomyxovirus, includes a compound capable of acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of orthomyxoviruses, and capable of binding to the viral-RNA-binding domain on the nucleoprotein of the viruses. A compound acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of influenza type A viruses, and binding to the viral-RNA-binding domain on the nucleoprotein of influenza type A viruses and a method for identifying such a compound having these properties are also described.Type: ApplicationFiled: April 20, 2012Publication date: June 12, 2014Applicant: Institut National de la Recherche AgronimiqueInventors: Anny Slama Schwok, Bernard Delmas, Stephane Quideau, Helene Bertrand, Bogdan Tarus
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Publication number: 20140005428Abstract: A metal organic framework (MOF) material including a Brunauer-Emmett-Teller (BET) surface area greater than 7,010 m2/g. Also a metal organic framework (MOF) material including hexa-carboxylated linkers including alkyne bond. Also a metal organic framework (MOF) material including three types of cuboctahedron cages fused to provide continuous channels. Also a method of making a metal organic framework (MOF) material including saponifying hexaester precursors having alkyne bonds to form a plurality of hexa-carboxylated linkers including alkyne bonds and performing a solvothermal reaction with the plurality of hexa-carboxylated linkers and one or more metal containing compounds to form the MOF material.Type: ApplicationFiled: June 18, 2013Publication date: January 2, 2014Applicant: Northwestern UniversityInventors: Omar K. Farha, Joseph T. Hupp, Christopher E. Wilmer, Ibrahim Eryazici, Randall Q. Snurr, Diego A. Gomez-Gualdron, Bhaskarjyoti Borah
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Publication number: 20130345249Abstract: The invention encompasses pharmaceutical formulations for the prevention and treatment of Wolbachia-related disease wherein the formulations comprise a compound previously unknown and unused for such a purpose, the compound being one or more of: Pararosaniline Pamoate, Pyrvinium Pamoate, Clofoctol, and Isoreserpine, derivatives, metabolites, precursors, pro-drugs and variants thereof.Type: ApplicationFiled: January 13, 2012Publication date: December 26, 2013Applicant: The Regents of the University of CaliforniaInventors: Alain Debec, Laura Serbus, Frederic Landmann, William Sullivan
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Patent number: 8609727Abstract: The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.Type: GrantFiled: October 17, 2006Date of Patent: December 17, 2013Assignee: Bayer Intellectual Property GmbHInventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr, Dieter Lang
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Publication number: 20130237723Abstract: Provided are a fluorinated graphene oxide and a preparation method thereof. In the fluorinated graphene oxide, the mass percent of fluorine is 0.5%<F %<40%; the mass percent of carbon is 50%<C %<80%, and the mass percent of oxygen is 0.5%<0%<30%. The preparation method comprises the following steps: providing graphite; preparing graphene oxide by using the graphite; and subjecting the graphene oxide to reacting with a mixed gas of N2 and F2 at 20˜200° C. for 0.5˜24 h, to prepare the fluorinated graphene oxide. The preparation method is simple, has fewer steps, and has better prospect of application.Type: ApplicationFiled: December 22, 2010Publication date: September 12, 2013Inventors: Mingjie Zhou, Daxi Liu, Yaobing Wang
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Publication number: 20130232853Abstract: The present invention is directed generally to a method of production of biobased chemicals, biofuels, and lignin residues from lignin sources, including waste lignin. This method may allow for selectively producing biobased chemicals, biofuels, and lignin residues from lignin sources using certain processing methods. The methods for production of these biobased chemicals, biofuels, and lignin residues may be provided by chemical-induced processing, catalytic oxidative lignin depolymerisation processing, and catalytic hydroprocessing. Further, the catalytic hydroprocessing from processes including catalytic reduction processing, catalytic hydrodeoxygenation processing, and/or catalytic/dehydrogenation processing may also be used. The method described herein also provides a means in which waste from the process(es) may be reduced and/or recycled.Type: ApplicationFiled: May 14, 2012Publication date: September 12, 2013Applicant: THESIS CHEMISTRY, LLCInventors: John R. Peterson, Jignesh S. Patel, Vladimir Romakh, Benjamin M.T. Scott
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Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration
Patent number: 8470075Abstract: Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.Type: GrantFiled: September 10, 2012Date of Patent: June 25, 2013Assignee: Northwestern UniversityInventors: Omar K. Farha, Joseph T. Hupp -
Publication number: 20130137894Abstract: A chemically-modified graphene includes a graphene layer and a plurality of functional groups that are grafted to the graphene layer and each of which is represented by —CO—R—COOH, wherein R is an optionally substituted C1-C5 alkylene group or an optionally substituted C1-C5 alkenylene group. A method for producing a chemically-modified grapheme includes subjecting a cyclic anhydride and graphite to a Friedel-Crafts reaction in the presence of a Lewis acid.Type: ApplicationFiled: September 14, 2012Publication date: May 30, 2013Applicant: Chang Gung UniversityInventors: Mu-Yi Hua, Shi-Liang Chen, Hsiao-Chien Chen, Rung-Ywan Tsai, Wu-Shiung Feng, Ming-Jer Jeng
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Patent number: 8426636Abstract: A sterically bulky stabilizer that is associated non-covalently with a benzimidazolone pigment. The sterically bulky stabilizer compound includes an aromatic acid derivative, and the presence of the sterically bulky stabilizer limits an extent of particle growth and aggregation, to afford nanoscale pigment particles.Type: GrantFiled: July 25, 2011Date of Patent: April 23, 2013Assignees: Xerox Corporation, National Research Council of CanadaInventors: Rina Carlini, Darren Andrew Makeiff
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Publication number: 20130079552Abstract: The present invention relates to a novel graphene oxide reducing agent and a method for manufacturing a reduced graphene oxide from graphene oxide using same. More particularly, in the present invention, the reduced graphene oxide is manufactured by reducing a graphene oxide using a reducing agent containing a halogen element, and is applicable as an electric conductor, a semiconductor, and an insulator in various fields.Type: ApplicationFiled: September 1, 2010Publication date: March 28, 2013Inventors: Hyo Young Lee, In Kyu Moon, Jung Hyun Lee
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Publication number: 20130072669Abstract: The present invention is directed to carbon nanostructures, e.g., carbon nanotubes, methods of covalently functionalizing carbon nanostructures, and methods of separating and isolating covalently functionalized carbon. In some embodiments, carbon nanotubes are reacted with alkylating agents to provide water soluble covalently functionalized carbon nanotubes. In other embodiments, carbon nanotubes are reacted with a thermally-responsive agent and exposed to light in order to separate carbon nanotubes of a specific chirality from a mixture of carbon nanotubes.Type: ApplicationFiled: April 4, 2012Publication date: March 21, 2013Applicant: University of Maryland, College ParkInventors: YuHuang Wang, Alexandra H. Brozena, Shunliu Deng, Yin Zhang
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Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration
Publication number: 20130061752Abstract: Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.Type: ApplicationFiled: September 10, 2012Publication date: March 14, 2013Applicant: Northwestern UniversityInventors: Omar K. Farha, Joseph T. Hupp -
Publication number: 20130053573Abstract: New triaminophenol compositions and related compounds are disclosed, as are processes for their preparation and for the preparation of novel salts and diacid complexes from such compounds. Polymers prepared from these compositions can be made into high strength fiber, film, and tape and are useful in applications such as protective apparel, aircraft, automotive components, personal electronics, and sports equipment.Type: ApplicationFiled: December 21, 2010Publication date: February 28, 2013Applicant: E I DU PONT DE NEMOURS AND COMPANYInventors: Rajiv Dhawan, Joachim C. Ritter
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Patent number: 8383545Abstract: A linking ligand compound includes three bidentate chemical moieties distributed about a central chemical moiety. Another linking ligand compound includes a bidentate linking ligand and a monodentate chemical moiety. Coordination polymers include a plurality of metal clusters linked together by residues of the linking ligand compounds.Type: GrantFiled: August 30, 2007Date of Patent: February 26, 2013Assignee: The Regents of the University of MichiganInventors: Adam J. Matzger, Antek G. Wong-Foy, Olivier Lebel
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Patent number: 8362295Abstract: Drilling fluids comprising graphenes and nanoplatelet additives and methods for production thereof are disclosed. Graphene includes graphite oxide, graphene oxide, chemically-converted graphene, and functionalized chemically-converted graphene. Derivatized graphenes and methods for production thereof are disclosed. The derivatized graphenes are prepared from a chemically-converted graphene through derivatization with a plurality of functional groups. Derivatization can be accomplished, for example, by reaction of a chemically-converted graphene with a diazonium species. Methods for preparation of graphite oxide are also disclosed.Type: GrantFiled: January 8, 2009Date of Patent: January 29, 2013Assignee: William Marsh Rice UniversityInventors: James M. Tour, Howard K. Schmidt, Condell D. Doyle, Dmitry V. Kosynkin, Jay R. Lomeda
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Publication number: 20120329871Abstract: A compound for use as an antimicrobial having a formula (A).Type: ApplicationFiled: December 21, 2010Publication date: December 27, 2012Applicant: THE UNIVERSITY OF WESTERN AUSTRALIAInventors: Allan James McKinley, Thomas V. Riley, Nigel Lengkeek, Scott Stewart, Ramiz Boulos
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Publication number: 20120309833Abstract: The present invention relates to analogs of bexarotene and methods of use thereof.Type: ApplicationFiled: February 17, 2011Publication date: December 6, 2012Inventors: Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall, Arjan van der Vaart
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Publication number: 20120289711Abstract: The present invention relates to a method for producing carbon nanomaterials and/or carbon micromaterials, in particular multi-wall carbon nanotubes. This method is characterized according to the invention in that the materials, in particular the side walls of the materials, undergo microwave-assisted functionalization. In addition, a correspondingly modified material is described.Type: ApplicationFiled: October 25, 2010Publication date: November 15, 2012Applicant: FUTURECARBON GMBHInventors: Jens Helbig, Christian Zenkel
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Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration
Patent number: 8262775Abstract: Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.Type: GrantFiled: October 13, 2009Date of Patent: September 11, 2012Assignee: Northwestern UniversityInventors: Omar K. Farha, Joseph T. Hupp -
Publication number: 20120183770Abstract: The present invention relates to the exfoliation and dispersion of carbon nanotubes resulting in high aspect ratio, surface-modified carbon nanotubes that are readily dispersed in various media. A method is disclosed for their production in high yield. Further modifications by surface active or modifying agents are also disclosed. Application of the carbon nanotubes of this invention as composites with materials such as elastomers, thermosets and thermoplastics are also described.Type: ApplicationFiled: June 20, 2011Publication date: July 19, 2012Inventors: Clive P. Bosnyak, Kurt W. Swogger
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Publication number: 20120170118Abstract: Presently described are multilayer optical films, oriented polyester films, negatively birefringent copolyester polymers, fluorene monomers, and polyester polymers prepared from such fluorene monomers. In one embodiment, the multilayer optical film comprises at least one first birefringent optical layer; and at least one second optical layer having a lower birefringence than the first optical layer; wherein at least one of the optical layers comprises a negatively birefringent polyester polymer comprising a backbone and repeat units comprising at least one pendent aromatic group that is conformationally locked relative to the backbone.Type: ApplicationFiled: November 23, 2011Publication date: July 5, 2012Inventors: Lei Wang, David T. Yust, George W. Griesgraber, Stephen A. Johnson, David S. Hays
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Patent number: 8173351Abstract: A compound shown by the following formula (1) can be used as a material for a radiation-sensitive composition capable of forming a resist film which effectively responds to electron beams or the like, exhibits low roughness, and can form a high precision minute pattern in a stable manner.Type: GrantFiled: January 8, 2008Date of Patent: May 8, 2012Assignee: JSR CorporationInventors: Daisuke Shimizu, Ken Maruyama, Toshiyuki Kai, Tsutomu Shimokawa
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Publication number: 20120101250Abstract: A dehydroabietic acid polymer includes a repeating unit containing a dehydroabietic acid skeleton, and a composite material including the same.Type: ApplicationFiled: June 24, 2010Publication date: April 26, 2012Applicant: FUJIFILM CORPORATIONInventors: Toshimitsu Sakuma, Kozo Sato
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Patent number: 8106236Abstract: The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R1, R2, R3, R4, R9, R10 given below, and solvates, hydrates, esters, and pharmaceutically acceptable salts thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of ?-secretase activity.Type: GrantFiled: April 19, 2007Date of Patent: January 31, 2012Assignee: Ortho-McNeil Pharmaceutical, Inc.Inventors: Francis Wilson, Alison Reid, Valerie Reader, Richard John Harrison, Mihiro Sunose, Remedios Hernandez-Perni, Jeremy Major, Cyrille Boussard, Kathryn Smelt, Jess Taylor, Adeline LeFormal, Andrew Cansfield, Svenja Burckhardt, Yan Zhang, Chih Yung Ho
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Publication number: 20110301305Abstract: According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride. [Chem. 134] AOCF2C-Q-CF2COA???(M-1) In the above formula, Q represents a divalent organic group having a substituted or unsubstituted aromatic ring; and A and A? each independently represent an organic group. This polymer exhibits a sufficiently low dielectric constant for use as a semiconductor protection film and has the capability of forming a film at a relatively low temperature of 250° C. or lower.Type: ApplicationFiled: February 18, 2010Publication date: December 8, 2011Applicant: CENTRAL GLASS COMPANY, LIMITEDInventors: Yoshimi Isono, Satoru Narizuka, Hidehisa Nanai, Kazuhiro Yamanaka
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Patent number: 8067466Abstract: The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient.Type: GrantFiled: June 9, 2008Date of Patent: November 29, 2011Assignee: Esperion Therapeutics, Inc.Inventors: Jean-Louis Henri Dasseux, Daniela Carmen Oniciu
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Patent number: 7985876Abstract: The invention relates to novel substituted dibenzoic acid derivatives of formula (I), wherein A represents a group of formula (II) or (III), to methods for producing the same, and to their use in the treatment and/or prophylaxis of diseases. The invention also relates to the use of said substances in the production of drugs for the treatment and/or prophylaxis of diseases, especially in the treatment and/or prevention of cardiovascular diseases.Type: GrantFiled: March 15, 2008Date of Patent: July 26, 2011Assignee: Bayer Schering Pharma AktiengesellschaftInventors: Michael Hahn, Eva-Maria Becker, Andreas Knorr, Dirk Schneider, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Dieter Lang
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Publication number: 20110144386Abstract: Drilling fluids comprising graphenes and nanoplatelet additives and methods for production thereof are disclosed. Graphene includes graphite oxide, graphene oxide, chemically-converted graphene, and functionalized chemically-converted graphene. Derivatized graphenes and methods for production thereof are disclosed. The derivatized graphenes are prepared from a chemically-converted graphene through derivatization with a plurality of functional groups. Derivatization can be accomplished, for example, by reaction of a chemically-converted graphene with a diazonium species. Methods for preparation of graphite oxide are also disclosed.Type: ApplicationFiled: January 8, 2009Publication date: June 16, 2011Applicant: William Marsh Rice UniversityInventors: James M. Tour, Howard K. Schmidt, Condell D. Doyle, Dmitry V. Kosynkin, Jay R. Lomeda
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Publication number: 20110110886Abstract: Autotaxin (ATX) is a prometastatic enzyme initially isolated from the conditioned media of human melanoma cells that stimulates a myriad of biological activities including angiogenesis and the promotion of cell growth, survival, and differentiation through the production of lysophosphatidic acid (LPA). ATX increases the aggressiveness and invasiveness of transformed cells, and ATX levels directly correlate with tumor stage and grade in several human malignancies. To study the role of ATX in the pathogenesis of malignant melanoma, we developed antibodies and small molecule inhibitors against recombinant human protein. Immunohistochemistry of paraffin embedded human tissue demonstrates that ATX levels are markedly increased in human primary and metastatic melanoma relative to benign nevi. Chemical screens identified several small molecule inhibitors with binding constants ranging from nanomolar to low micromolar.Type: ApplicationFiled: June 15, 2009Publication date: May 12, 2011Inventor: Demetrios Braddock
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Publication number: 20110077298Abstract: The invention relates to a retinoid derivative and pharmaceutical composition and use thereof. The compound of the invention is capable of preventing or treating hematological tumours, such as acute leukemia, chronic leukemia, multiple myeloma and lymphoma, solid tumours, such as liver cancer, rectal cancer, mammary cancer and esophagus cancer, and skin disorders, such as psoriasis and acne.Type: ApplicationFiled: May 31, 2009Publication date: March 31, 2011Applicants: ANHUI MEDICAL UNIVERSITY, Anhui New Star Pharmaceutical Development Co., LtdInventors: Feihu Chen, Jingbo Shi, Yuan Wang, Jun Li, Juan Shen, Jingjing Ruan, Fanrong Wu
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Publication number: 20110068290Abstract: Compounds, compositions, systems and methods for the chemical and electrochemical modification of the electronic structure of graphene and especially epitaxial graphene (EG) are presented. Beneficially, such systems and methods allow the large-scale fabrication of electronic EG devices. Vigorous oxidative conditions may allow substantially complete removal of the EG carbon atoms and the generation of insulating regions; such processing is equivalent to that which is currently used in the semiconductor industry to lithographically etch or oxidize silicon and thereby define the physical features and electronic structure of the devices. However graphene offers an excellent opportunity for controlled modification of the hybridization of the carbon atoms from sp2 to sp3 states by chemical addition of organic functional groups.Type: ApplicationFiled: May 29, 2009Publication date: March 24, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Robert C. Haddon, Mikhail E. Itkis, Palanisamy Ramesh, Elena Bekyarova, Sakhrat Khizroev, Jeongmin Hong
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Publication number: 20110064892Abstract: This invention relates to polycyclic organic compounds of general structural formula (I): wherein Y is a predominantly planar polycyclic system being at least partially aromatic, W1, W2, and W3 are different groups providing solubility in an organic solvent, and sum (n1+n2+n3) is 1, 2, 3, 4, 5, 6, 7 or 8. The polycyclic organic compounds are substantially transparent for electromagnetic radiation in the visible spectral range and are capable of forming supramolecules in the organic solvent.Type: ApplicationFiled: March 4, 2009Publication date: March 17, 2011Inventors: Alexey Nokel, Pavel I. Lazarev
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Patent number: 7901745Abstract: 3,4-Dicarboxy-1,2,3,4-tetrahydro-6-t-butyl-1-naphthalene-succinic dianhydride is provided. The tetracarboxylic dianhydride is represented by Formula 1, which is described in the specification. Further provided is a liquid crystal aligning agent comprising a polyimide prepared using the tetracarboxylic dianhydride and a solvent. Further provided is a liquid crystal alignment layer formed using the liquid crystal aligning agent. The liquid crystal alignment layer exhibits excellent electro-optical properties and good processability in terms of printability.Type: GrantFiled: June 2, 2009Date of Patent: March 8, 2011Assignee: Cheil Industries Inc.Inventors: Jae Min Oh, Tae Hyoung Kwak, Ji Young Jeong
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Publication number: 20110015426Abstract: A liquid crystalline compound has excellent liquid crystal properties, particularly high phase transition temperature. Diamantane compounds are represented by the general formula (I): (I) wherein A and B are each a six-membered, saturated or unsaturated, carbo- or hetero-cycle, and these cycles may have substituents, which substituents may be united to form a ring; and R1 and R2 are each a hydrocarbon group having 1 to 18 carbon atoms, and part of the carbon atoms of the hydrocarbon group may be replaced by heteroatoms or heteroatom-containing groups, while part of the hydrogen atoms thereof may be replaced by halogen atoms or heteroatom-containing groups.Type: ApplicationFiled: March 11, 2008Publication date: January 20, 2011Applicants: NATIONAL UNIVERSITY CORPORATION YOKOHAMA, JX NIPPON OIL & ENERGY CORPORATIONInventors: Yasushi Yokoyama, Tsuyoshi Gushiken, Takashi Ubukata
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Publication number: 20100298347Abstract: Substituted 2-naphthoic acids of structural formula are effective as antagonists of the biological activity of GPR105 protein. They are useful for the treatment, control or prevention of disorders responsive to antagonism of this receptor, such as diabetes, particularly, Type 2 diabetes, insulin resistance, hyperglycemia, lipid disorders, obesity, atherosclerosis, and conditions associated with the Metabolic Syndrome.Type: ApplicationFiled: December 1, 2008Publication date: November 25, 2010Applicant: MERCK FROSST CANADA LTDInventors: Michel Belley, Denis Deschenes, Rejean Fortin, Jean-Francois Fournier, Sebastien Gagne, Yves Gareau, Jacques Yves Gauthier, Lianhai Li, Joel Robichaud, Michel Therien, Geoffrey K. Tranmer, Zhaoyin Wang
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Patent number: 7816385Abstract: A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator -Activated Receptors (PPAR).Type: GrantFiled: December 12, 2003Date of Patent: October 19, 2010Assignee: High Point Pharmaceuticals, LLCInventors: Per Sauerberg, Lone Jeppesen, Zdenek Polivka, Karel Sindelar
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Publication number: 20100222543Abstract: Improved process for the continuous production of slow crystallizing polyester resin comprising esterification of at least one dicarboxylic acid or mono-esters thereof or di-esters thereof with at least one polyol, melt polymerizing the esterified mixture, preparing uniform crystalline hemispherical prepolymer by particle former process, adding at least one diol having tertiary or quaternary carbon atoms with pendant groups such as neopentyl glycol or 2-methyl-1,3-propanediol or any suitable diol at any stage during esterification or melt polymerization but before the particle former process; and solid state polymerizing the prepolymer to obtain high molecular weight slow crystallizing polyester. Slow crystallizing low molecular weight crystalline hemispherical prepolymer having IV of about 0.1 dl/g to about 0.45 and uniform hemispherical shape, uniform particle size, uniform crystallinity prepared by the above process and is used as precursor to prepare high molecular weight resin.Type: ApplicationFiled: August 14, 2006Publication date: September 2, 2010Applicant: Reliance Industries LtdInventors: Vikas Madhusudan Nadkarni, Srinivasacharya Ramacharya Ayodhya, Shreeram Ashok Wadekar, Ashwin Kumar Jain, Sachin Narayan Rane, Chetan Vijay Limaye
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Publication number: 20100204199Abstract: Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-Beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: enantiomers, diastereomers, solvates, or salts thereof, wherein A, W, X and Z are defined herein.Type: ApplicationFiled: April 14, 2010Publication date: August 12, 2010Inventors: Xiang-Yang Ye, Jeffrey A. Robl, Ronald L. Hanson, Zhiwei Guo, Ramesh N. Patel
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Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration
Publication number: 20100170395Abstract: Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.Type: ApplicationFiled: October 13, 2009Publication date: July 8, 2010Inventors: Omar K. Farha, Joseph T. Hupp