Oxy Containing Patents (Class 562/564)
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Patent number: 11242265Abstract: A system and method treat oilfield produced water by two-stages of hazardous sulfide treatments. In an embodiment, a two-stage oil and gas field produced water treatment system includes an oil removal vessel. The oilfield produced water is introduced to the oil removal vessel. The oil removal vessel removes a portion of the hydrocarbons from the oilfield produced water to provide a reduced oil produced water. In addition, the system includes an iron sponge. The reduced oil produced water is introduced to the iron sponge, and the iron sponge removes a portion of the hazardous sulfides from the reduced oil produced water to provide a reduced sulfide produced water. The system also includes a stabilized sodium percarbonate solution. The stabilized sodium percarbonate solution is mixed with the reduced sulfide produced water to remove a portion of the hazardous sulfides from the reduced sulfide produced water to provide a treated produced water.Type: GrantFiled: February 14, 2017Date of Patent: February 8, 2022Assignee: United Laboratories International, LLCInventors: Stephen D. Matza, Martha T. Smith
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Patent number: 10982124Abstract: The present application provides a drill-in slurry containing an aqueous base fluid; a solid particulate material; a hygroscopic chelating agent; optionally an alkali formate; and optionally an additional ingredient such as a defoamer, a viscosity modifier, a stabilizer, soda ash or sodium bicarbonate. Methods for making the drill-in slurry and methods of using the drill-in slurry for drilling into a reservoir section or a producing section of a subterranean formation are also provided.Type: GrantFiled: November 6, 2017Date of Patent: April 20, 2021Assignee: Saudi Arabian Oil CompanyInventors: Hussain AlBahrani, Abdullah Saleh Hussain Al-Yami, Abdulla Hussein Al-Awadh
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Publication number: 20150096528Abstract: A fuel soluble additive for a diesel engine, a method for improving performance of fuel injectors and a method for cleaning fuel injectors for a diesel engine. The fuel soluble additive includes a quaternary ammonium salt derived from the reaction of (a) a hydrocarbyl amine containing at least one tertiary amino group, (b) an epoxide compound selected from a glycidol, a glycidyl ether, glycidyl ester, polyglycidyl ether, a polyglycidyl ester, and combinations thereof, wherein substituents of the glycidyl group have, on average, less than five carbon atoms per hetero atom, and (c) optionally a proton donor.Type: ApplicationFiled: October 8, 2013Publication date: April 9, 2015Applicant: Afton Chemical CorporationInventors: Scott D. SCHWAB, Xinggao FANG
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Patent number: 8927767Abstract: This invention discloses novel crystalline polymorphs of acetyl-glycine-beta-alanine and process of making the same. The mentioned crystalline polymorphs can exhibit excellent purity and storage stability according to this invention. Therefore, the mentioned crystalline polymorphs can be applied in topical cosmetic compositions, pharmaceutical compositions as skin care preparations, or other functional preparations.Type: GrantFiled: May 6, 2014Date of Patent: January 6, 2015Assignee: Corum Inc.Inventor: Nai-Hsuan Hsu
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Publication number: 20140364642Abstract: [Problem] Provision of a novel compound having read-through activity and a drug for the treatment of nonsense mutation-type disease containing this compound. [Solution] A compound represented by the following general formula (1): and a pharmaceutical composition containing this compound.Type: ApplicationFiled: May 30, 2014Publication date: December 11, 2014Applicant: THE UNIVERSITY OF TOKYOInventors: Yoshio HAYASHI, Akihiro TAGUCHI, Fumika YAKUSHIJI, Yuri YAMAZAKI, Ryoichi MATSUDA, Masataka SHIOZUKA
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Patent number: 8901355Abstract: Provided are new dendrimers and processes for making them. The dendrimers are derived from a nitroalkyloxirane compound of formula (III): wherein R1, R2, and R3 are as described herein.Type: GrantFiled: May 17, 2012Date of Patent: December 2, 2014Assignees: Dow Global Technologies LLC, ANGUS Chemical CompanyInventors: Ian A. Tomlinson, Asghar A. Peera
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Publication number: 20140346089Abstract: The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.Type: ApplicationFiled: April 22, 2014Publication date: November 27, 2014Inventors: David S. Soane, Rosa Casado Portilla, John H. Dise, Robert P. Mahoney
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Publication number: 20140323390Abstract: The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 2. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.Type: ApplicationFiled: July 9, 2014Publication date: October 30, 2014Applicant: IRM LLCInventors: Tom Yao-Hsiang WU, Yefen Zou, Timothy Z. Hoffman, Jianfeng Pan
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Publication number: 20140309401Abstract: A DPP-4 inhibitor comprising a peptide represented by the formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe is an amino acid residue with an isoelectric point of 5.9 to 6.3; Pro/Ala/Hyp represents Pro, Ala, or Hyp; Xa is an amino acid residue other than Hyp, Pro, and Arg, or deletion; Xb is Gly, Pro, or deletion; Xc is Pro, Ala, or deletion; and Xd is an amino acid residue or deletion) as an active component. The inhibitor can be expected to bring out an effect of lowering blood glucose levels by enhancing effects of incretins; and the inhibitor may be used as a therapeutic agent for diabetes and, in addition, can act on the immune system or the like to be thus used in treatment for skin diseases or the like.Type: ApplicationFiled: November 2, 2012Publication date: October 16, 2014Inventors: Osamu Hayashida, Masashi Kusubata, Yuji Atsuzawa, Yuki Taga, Youichi Koyama, Shunji Hattori
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Publication number: 20140303397Abstract: The present invention provides novel polymerizable monomers having chelating functionality and processes to make them. In particular, the novel monomers are ethylenically unsaturated aminocarboxylates and are prepared by reacting ethylenediamine triacetic acid or its salt with an ethylenically unsaturated monomer. The ethyleneically unsaturated monomer may be a polymerizable vinyl monomer selected from (o-, p-, m-)DVBMO, allyl glycidyl ether, and glycidyl (meth)acrylate.Type: ApplicationFiled: October 31, 2012Publication date: October 9, 2014Applicants: ROHM AND HAAS COMPANY, DOW GLOBAL TECHNOLOGIES LLCInventors: Scott Backer, Allen Bulick, Joseph Manna, Cynthia Rand, Jia Xie
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Publication number: 20140303063Abstract: The invention relates to a washing or cleaning agent, wherein use thereof generates hydrogel layers surfaces, comprising a hydrogel former having a molecular weight less than 3500 g/Mol, wherein the hydrogel former is water-soluble at concentrations below the minimum gel formation concentration, wherein the minimum gel formation concentration is the concentration at which a yield point of at least 0.05 Pa is formed in a binary solution of water and hydrogel former at T=25° C., and wherein said minimum gel formation concentration lies below 2 wt % of hydrogel former, relative to the system consisting of water and hydrogel former. The washing or cleaning agents according to the invention enable the hydrophiliation of surfaces, and the specific and retarded releasing of active substances embedded in the hydrogel layers, such as aromatic substances or antimicrobial active substances, for example.Type: ApplicationFiled: April 3, 2014Publication date: October 9, 2014Applicant: Henkel AG & Co. KGaAInventors: Christian Kropf, Matthias Sunder, Peter Schmiedel, Ulrich Pegelow, Joerg C. Tiller, Marco Mueller, Kaoru Tachikawa, Yvonne Willemsen
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Publication number: 20140239241Abstract: The present invention provides a macromolecular dispersant and a synthesis method thereof, and the dispersant is synthesized by reacting polyisobutylene-g-succinic anhydride with amine compounds. In addition, the present invention also provides an oil-soluble dispersant composition with nano particle pigments and the manufacturing method thereof. The oil-soluble dispersant composition is manufactured by milling a macromolecular dispersant with a pigment and a grinding media. The oil-soluble dispersant composition is adequate for various pigments, shows the excellent immiscibility of oil/water interface, and owns the low viscosity of ?4 cps and the optical density of ink ?1.1. Therefore, the oil-soluble dispersant of the present invention for the nano particle pigment can be acted as the material of the electrowetting display.Type: ApplicationFiled: January 3, 2014Publication date: August 28, 2014Applicant: National Taiwan UniversityInventors: Jiang-Jen Lin, Chih-Wei Chiu, Tzu-Chien Lee, Ling-Yu Chang
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Publication number: 20140234187Abstract: The objective of the present invention is to selectively extract light rare earth metals, and by extension, europium, from an acidic solution containing a plurality of types of rare earth metal. This valuable metal extraction agent is represented by the general formula. In the formula: R1 and R2 each indicate the same or different alkyl group; R3 indicates a hydrogen atom or an alkyl group; and R4 indicates a hydrogen atom or any given group other than an amino group bonded to the ? carbon as an amino acid. Preferably, the general formula has a glycine unit, a histidine unit, a lysine unit, an aspartic acid unit, or an N-methylglycine unit. Preferably, when extracting europium using the extraction agent, the pH is adjusted into the range of 2.0-3.0 inclusive, and when selectively extracting light rare earth metals, the pH is adjusted to 1.7-2.7 inclusive.Type: ApplicationFiled: November 2, 2012Publication date: August 21, 2014Applicants: SUMITOMO METAL MINING CO., LTD., Kyushu University, National University CorporationInventors: Masahiro Goto, Fukiko Kubota, Yuzo Baba
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Patent number: 8785679Abstract: Hydrophilic, biocidal coating compositions and methods to make and use the compositions are disclosed. The coatings include compounds with quaternary amine polyethylene glycol groups and polyaminoalkyl biguanide groups as substituents. The compounds when incorporated in paints provide hydrophilic, self-cleaning and biocidal property to the coating.Type: GrantFiled: December 10, 2012Date of Patent: July 22, 2014Assignee: Empire Technology Development LLCInventors: Glen Leon Brizius, Phillip Kent Montgomery
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Publication number: 20140154183Abstract: What is described are the compounds and the synthesis of [F-18]-labelled L-glutamic acid, [F-18]-labelled L-glutamate, their derivatives of the formula (I) and their use.Type: ApplicationFiled: February 5, 2014Publication date: June 5, 2014Inventors: Matthias FRIEBE, Heribert SCHMITT-WILLICH, Matthias BERNDT, Ludger DINKELBORG, Norman KOGLIN, Keith GRAHAM
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Publication number: 20140135486Abstract: A multi-arm polyethylene glycol (I) having different kinds of reactive groups and the uses thereof are disclosed, which is formed by polymerizing ethylene oxide with oligo-pentaerythritol as an initiator, wherein, PEG is same or different and is —(CH2CH2O)m—, the average value of m is an integer of 2-250; l is an integer of 1 or more. The method for producing the multi-arm polyethylene glycol having different kinds of reactive groups, the multi-arm polyethylene glycol active derivatives comprising linking groups X attached to PEG and terminal reactive groups F attached to X, the gels formed by the multi-arm polyethylene glycol active derivatives, the drug conjugates formed by the multi-arm polyethylene glycol active derivatives and drug molecules, and the uses thereof in preparing drugs are also disclosed.Type: ApplicationFiled: January 21, 2014Publication date: May 15, 2014Applicant: JENKEM TECHNOLOGY CO., LTD, TIANJIN BRANCHInventors: Xuan Zhao, Meina Lin
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Publication number: 20140113884Abstract: Compounds and compositions comprising epoxyeicosatrienoic acid (EET) analogs that act as EET agonists and are useful as medications in the treatment of drug-induced nephrotoxicity, hypertension and other related conditions. Methods of making and using the compounds and compositions are further described.Type: ApplicationFiled: April 4, 2012Publication date: April 24, 2014Inventors: John David Imig, William B. Campell, John Russell Falck
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Publication number: 20140081045Abstract: Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power.Type: ApplicationFiled: September 16, 2012Publication date: March 20, 2014Applicant: Rohm and Haas Electronic Materials LLCInventors: Erik Reddington, Gonzalo Urrutia Desmaison, Zukra I. Niazimbetova, Donald E. Cleary, Mark Lefebvre
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Publication number: 20140057816Abstract: The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.Type: ApplicationFiled: November 5, 2012Publication date: February 27, 2014Applicant: Soane Energy, LLCInventors: David S. Soane, Rosa Casado Portilla, John H. Dise, Robert P. Mahoney
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Publication number: 20140010939Abstract: The present invention relates to novel sweetness enhancer compounds of the formula (I), or a stereoisomer or a salt or a hydrate thereof, to the use of a compound of formula (I) or a stereoisomer or a salt or a hydrate thereof as a sweetness enhancer, to sweetener compositions comprising at least one sweetener and a compound of formula (I) or a stereoisomer or a salt or a hydrate thereof, to a method for the manufacture of a compound of formula (I) or a stereoisomer or a salt or a hydrate thereof, to methods of making the sweetener compositions and to tabletop sweetener compositions comprising a compound of formula (I) or a stereoisomer or a salt or a hydrate thereof. Further, the invention relates to consumables comprising a consumable product and a compound of formula (I) or a stereoisomer or a salt or a hydrate thereof.Type: ApplicationFiled: February 7, 2012Publication date: January 9, 2014Applicant: Nutrinova Nutrition Specialties & Food Ingredients GmbHInventors: Michael Krohn, Simon Seibert, Alice Kleber, Johann Wonschik, Karsten Siems, Jens-Peter Muller, Lars Ole Haustedt, Oliver Schwarz
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Publication number: 20130340326Abstract: Gemini surfactants of bis-N-alkyl polyether, bis-N-alkenyl polyether, bis-N-cycloalkyl polyether, bis-N-aryl polyether bis-beta or alpha-amino acids or their salts, are produced for use as multifunctional corrosion inhibitors, which protect and prevent corrosion of ferrous metals exposed to acidic, basic and neutral liquids when transporting or storing crude oil and liquid fuels. The surfactants are also used to inhibit corrosion of equipment and pipes used in cooling systems in petroleum and petrochemical equipment.Type: ApplicationFiled: July 18, 2013Publication date: December 26, 2013Applicant: INSTITUTO MEXICANO DEL PETROLEOInventors: Raul HERNANDEZ ALTAMIRANO, Violeta Yasmin MENA CERVANTES, Luis Silvestre ZAMUDIO RIVERA, Hiram Isaac BELTRAN CONDE, Simon LOPEZ RAMIREZ
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Publication number: 20130323777Abstract: A ligand design allows compact nanoparticle materials, such as quantum dots (QDs), with excellent colloidal stability over a wide range of pH and under high salt concentrations. Self-assembled biomolecular conjugates with QDs can be obtained which are stable in biological environments. Energy transfer with these ligands is maximized by minimizing distances between QDs/nanoparticles and donors/acceptors directly attached to the ligands or assembled on their surfaces.Type: ApplicationFiled: July 16, 2013Publication date: December 5, 2013Applicant: Naval Research LaboratoryInventors: Igor L. Medintz, Kimihiro Susumu, Michael H. Stewart
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Patent number: 8536375Abstract: The present invention provides novel and more efficient synthesis's for obtaining an intermediate in the synthesis of obtaining a protecting group aminoxy PEG linker.Type: GrantFiled: December 7, 2009Date of Patent: September 17, 2013Assignee: GE Healthcare LimitedInventor: Torgrim Engell
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Publication number: 20130209439Abstract: The present invention provides methods and materials for use in increasing HSP20 activation in a biological system, for example by increasing phosphorylation of Ser16 of HSP20. In one aspect, the invention provides a method for increasing HSP20 activation in a biological system, comprising contacting the system with an antagonist capable of inhibiting PDE4 binding to HSP20, the antagonist comprising or consisting essentially of a fragment of PDE4 or an analogue thereof. In a further aspect the invention provides a method of screening for an agent able to increase activation of HSP20. A preferred antagonist has a C-terminal lysine residue.Type: ApplicationFiled: October 7, 2011Publication date: August 15, 2013Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOWInventors: George S. Baillie, Miles Houslay, Jon Day
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Publication number: 20130177961Abstract: Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms polya and polyb, respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEGa and mPEGb have the structure CH3O—(CH2CH2O)nCH2CH2— where n may be the same or different for polya- and polyb- and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.Type: ApplicationFiled: December 14, 2012Publication date: July 11, 2013Applicant: NEKTAR THERAPEUTICSInventor: NEKTAR THERAPEUTICS
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Publication number: 20130131310Abstract: The present invention relates to methods for synthesizing compounds of formula I or pharmaceutically acceptable salts thereof: (I) wherein each of X, Alk, and W are as defined and described herein.Type: ApplicationFiled: July 22, 2011Publication date: May 23, 2013Inventors: John Kane, Thomas M. Lancaster, Todd C. Zion
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Publication number: 20130096340Abstract: An amino acid-modified organopolysiloxane is provided. It has an amino acid derivative bonded to at least one silicon atom of the organopolysiloxane segment constituting the backbone of the organopolysiloxane via an amide bond represented by the following general formula (1): wherein X and Y are independently a C1-10 divalent hydrocarbon group; m is an integer of 0 to 4; Ra is hydrogen atom, a monovalent hydrocarbon group containing 1 to 4 carbon atoms, or an organic group represented by the following general formula (2): (wherein Rb is hydrogen atom, a C1-7 monovalent hydrocarbon group, an alkaline metal, or an alkaline earth metal, and Rc is independently hydrogen atom, hydroxy group, or a C1-10 monovalent hydrocarbon group optionally containing oxygen atom, sulfur atom, or nitrogen atom); and Z is an organic group represented by the general formula (2).Type: ApplicationFiled: December 4, 2012Publication date: April 18, 2013Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventor: SHIN-ETSU CHEMICAL CO., LTD.
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Patent number: 8389657Abstract: A composition comprising a copolymer having repeating units in any sequence of Formula I wherein Rf is a straight or branched perfluoroalkyl group which is optionally interrupted by at least one oxygen atom, X3 is oxygen or X1, each X1 is independently an organic divalent linking group, G is F or CF3, A is an amide, X2 is an organic linking group, Y is O, N or S, Z is H, a straight or branched alkyl group or halide, B is H or wherein Rf, X1, X3, G, and A are as defined above, and each W is independently various copolymer units.Type: GrantFiled: April 13, 2012Date of Patent: March 5, 2013Assignee: E. I. du Pont de Nemours and CompanyInventor: Weiming Qiu
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Publication number: 20130052130Abstract: Disclosed are general and “substantially pure” branched discrete polyethylene glycol constructs useful in attaching to a variety of biologically active groups, for example, preferential locators, as well as biologics like enzymes, for use in diagnostics, e.g. imaging, therapeutics, theranostics, and moieties specific for other applications. In its simplest intermediate state, a branched discrete polyethylene glycol construct is terminated at one end by a chemically reactive moiety, “A”, a group that is reactive with a biologic material that creates “A”, which is a biologically reactive group, connected through to a branched core (BC) which has attached at least two dPEG-containing chains, indicated by the solid line, , having terminal groups, which can be charged, non-reactive or reactable moieties and containing between about 2 and 64 dPEG residues.Type: ApplicationFiled: August 30, 2012Publication date: February 28, 2013Applicants: UNIVERSITY OF WASHINGTON, QUANTA BIODESIGN, LTD.Inventors: Paul D. Davis, D. Scott Wilbur
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Publication number: 20130053315Abstract: Novel polypeptide derivatives having protracted profile of action.Type: ApplicationFiled: March 22, 2012Publication date: February 28, 2013Inventors: Jesper Lau, Thomas Kruse Hansen, Kjeld Madsen, Paw Bloch, Florencio Zaragoza Dorwald, Nils Langeland Johansen
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Publication number: 20130040884Abstract: Novel polypeptide derivatives having protracted profile of action.Type: ApplicationFiled: March 22, 2012Publication date: February 14, 2013Inventors: Jesper Lau, Thomas Kruse Hansen, Kjeld Madsen, Paw Bloch, Florencio Zaragoza Dorwald, Nils Langeland Johansen
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Publication number: 20130030033Abstract: This invention relates to novel 4-trimethylammoniobutyrates of the formula wherein A1, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments.Type: ApplicationFiled: October 5, 2012Publication date: January 31, 2013Applicant: Hoffmann-La Roche Inc.Inventor: Hoffmann-La Roche Inc.
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Patent number: 8344027Abstract: This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formula wherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors.Type: GrantFiled: April 28, 2009Date of Patent: January 1, 2013Assignee: Hoffmann-La Roche Inc.Inventors: Mirjana Andjelkovic, Simona M. Ceccarelli, Odile Chomienne, Gerald Lewis Kaplan, Patrizio Mattei, Jefferson Wright Tilley
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Publication number: 20120309944Abstract: The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there altered profile considered particular useful in therapy.Type: ApplicationFiled: January 24, 2011Publication date: December 6, 2012Applicant: Novo Nordisk Health Care AGInventors: Carsten Behrens, Nils Langeland Johansen, Henrik Sune Andersen, Leif Noerskov-Lauritsen, Jens Buchardt
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Publication number: 20120270813Abstract: A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide product having cholecystokinin secretion promoting effect is obtained. Also disclosed is the composition containing the peptide product and the use thereof.Type: ApplicationFiled: October 5, 2011Publication date: October 25, 2012Applicant: Food Industry Research and Development InstituteInventors: Yi-Hong Chen, Yu-Hui Liu, Chu-Chin Chen, Shiao-Cheng Chuang, Hsiang-Ling Lai, Chien-Ti Chang, Ming-Yu Hung, Su-Er Liou, Fu-Ning Chien
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Publication number: 20120264972Abstract: A composition comprising a copolymer having repeating units in any sequence of Formula I wherein Rf is a straight or branched perfluoroalkyl group which is optionally interrupted by at least one oxygen atom, X3 is oxygen or X1, each X1 is independently an organic divalent linking group, G is F or CF3, A is an amide, X2 is an organic linking group, Y is O, N or S, Z is H, a straight or branched alkyl group or halide, B is H or wherein Rf, X1, X3, G, and A are as defined above, and each W is independently various copolymer units.Type: ApplicationFiled: April 13, 2012Publication date: October 18, 2012Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventor: WEIMING QIU
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Patent number: 8206692Abstract: The present invention relates to a method for screening compounds having the ability to prevent, treat or reduce malodor development on body surfaces. In particular, the method allows to efficiently screen for compound having the ability of preventing sweat malodor development caused by volatile sulfur compounds (VSCs). The present invention is based on the finding of the direct precursor of naturally VSCs, which is present in human sweat and which will be metabolized by Staphylococci to VSCs.Type: GrantFiled: July 18, 2007Date of Patent: June 26, 2012Assignee: Firmenich SAInventors: Christian Starkenmann, Anthony Clark, Myriam Troccaz, Yvan Niclass
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Publication number: 20120010360Abstract: A modified layered material is provided, which includes a layered inorganic material intercalated with an organic modifier. The organic modifier includes wherein M includes a metal and R1 includes a carbon chain. An unsaturated polyester nanocomposite is also provided, which includes a polymer material including unsaturated polyester and the modified layered material, wherein the modified layered material is dispersed in the polymer material and is at least partially exfoliated.Type: ApplicationFiled: September 23, 2011Publication date: January 12, 2012Applicants: UNITED SHIP DESIGN & DEVELOPMENT CENTER, CHUNG YUAN CHRISTIAN UNIVERSITYInventors: Tsung-Yen Tsai, Chien-Hung Kuo, Cheng-Hsien Chung, Chia-Hao Hsu
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Publication number: 20120004423Abstract: The present invention provides novel and more efficient synthesis's for obtaining an intermediate in the synthesis of obtaining a protecting group aminoxy PEG linker.Type: ApplicationFiled: December 7, 2009Publication date: January 5, 2012Applicant: GE HEALTHCARE LIMITEDInventor: Torgrim Engell
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Publication number: 20110229940Abstract: The present invention relates to a method for producing an L-amino acid by reacting an enantiomeric mixture of an N-succinyl amino acid with L-succinylase in the presence of N-acylamino acid racemase to specifically hydrolyze the L-form. In particular, the present invention relates to a method for producing an L-amino acid in high yield by using an N-succinyl amino acid whose dissolved concentration is particularly low as a raw material to perform a reaction while precipitating the produced L-amino acid out of the reaction system. The present invention enables efficient production of an L-amino acid having high optical purity, particularly an L-amino acid useful as a raw material for products such as pharmaceutical products and agricultural chemicals.Type: ApplicationFiled: October 28, 2009Publication date: September 22, 2011Applicant: KANEKA CORPORATIONInventors: Masutoshi Nojiri, Tozo Nishiyama, Naoaki Taoka
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Publication number: 20110207634Abstract: The present invention relates to a process for preparing ether carboxylates.Type: ApplicationFiled: February 18, 2011Publication date: August 25, 2011Applicant: BASF SEInventors: Robert Baumann, Markus Christian Biel, Andreas Deckers, Alfred Oftring, Frank Rittig, Wolfgang Staffel
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Publication number: 20110165076Abstract: What is described are the compounds and the synthesis of [F-18]-labelled L-glutamic acid, [F-18]-labelled L-glutamate, their derivatives of the formula (I) and their use.Type: ApplicationFiled: May 14, 2009Publication date: July 7, 2011Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFTInventors: Ludger Dinkelborg, Mathias Berndt, Matthias Friebe, Heribert Schmitt-Willich, Detlev Sülzle, Norman Koglin
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Publication number: 20110138683Abstract: The disclosure relates to new surfactants of bis-N-alkyl polyether, bis-N-alkenyl polyether, bis-N-cycloalkyl polyether, bis-N-aryl polyether bis-beta or alpha-imino acids or their salts, process for obtaining and using mainly as multifunctional corrosion inhibitors, which protect and prevent corrosion of ferrous metals exposed to acidic, basic and neutral when transporting or storing crude oil and liquid fuels, or to the equipment and pipes used in cooling systems industry petroleum and petrochemical industries.Type: ApplicationFiled: December 14, 2010Publication date: June 16, 2011Applicant: INSTITUTO MEXICANO DEL PETROLEOInventors: Raúl HERNÁNDEZ ALTAMIRANO, Violeta Yasmín MENA CERVANTES, Luis Silvestre ZAMUDIO RIVERA, Hiram Isaac BELTRÁN CONDE, Simón LÓPEZ RAMÍREZ
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Publication number: 20110130327Abstract: Multi-arm amine compounds and compositions for enhancing intracellular, in vitro, and in vivo delivery of drug, active, and therapeutic substances including ribonucleic acids. This disclosure provides novel compounds and compositions for making and using delivery materials and carriers which increase the efficiency of delivery of biologically active and pharmacologically active molecules. Embodiments of this disclosure may further provide delivery of various therapeutic agents including nucleic acid therapeutics such as regulatory RNA, interfering RNA, and agents for RNAi, as well as other protein and peptide therapeutics. In some aspects, this disclosure provides multi-arm amine compounds and compositions which can enhance permeation of a drug substance.Type: ApplicationFiled: November 26, 2010Publication date: June 2, 2011Applicant: MARINA BIOTECH, INC.Inventors: MICHAEL E. HOUSTON, JR., ROGER C. ADAMI, STEVEN C. QUAY, PHUONG NGUYEN, HARRY C. WANG, DIANE E. FRANK
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Publication number: 20110041725Abstract: Methods and compositions are provided for the reduction of fouling of objects present in marine environments. The methods and compositions include anticoagulants, such as, for example, glycosaminoglycans, coumarin-type molecules, metal chelators, plasminogen activators and platelet inhibitors. The methods include reducing marine fouling, comprising incorporating an anticoagulant compound into a marine coating. In addition, the methods include identifying compounds useful for reducing marine fouling, comprising measuring either blood coagulation or barnacle cement polymerization in the presence and absence of the compound, wherein a reduction in the blood coagulation or the barnacle cement polymerization in the presence of the compound identifies the compound as useful for reducing marine fouling. The coagulation or the polymerization can be measured by a serine protease activity or a transglutaminase activity.Type: ApplicationFiled: June 13, 2008Publication date: February 24, 2011Inventors: Daniel Rittschof, Gary H. Dickinson, Beatriz Orihuela de Diaz, Eric R. Holm
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Patent number: 7850928Abstract: The present invention provides: a fixed-bed shell-and-tube reactor, which can stably produce an aimed product for a long period when a solid particulate material such as a catalyst is packed and used for each substance; and its usage. The fixed-bed shell-and-tube reactor comprises a plurality of reaction tubes that are packed with a solid particulate material and arranged in parallel, wherein the solid particulate material is weighed so as to be uniform volume, and is packed in each reaction tube in a packing time of not shorter than 30 seconds per liter.Type: GrantFiled: April 23, 2006Date of Patent: December 14, 2010Assignee: Nippon Shokubai Co., Ltd.Inventors: Michio Tanimoto, Hideto Hashiba
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Patent number: 7799941Abstract: There is provided a process for efficiently producing an anti form of an optically active ?-hydroxy-?-aminocarboxylic acid derivative that is useful as an intermediate for pharmaceuticals and agrochemicals. The process for producing optically active ?-hydroxy-?-aminocarboxylic acid derivative of formula (2) or (3) wherein R1 is substituted or unsubstituted C1-20 alkyl group, or substituted or unsubstituted C4-12 aromatic group, R2 is substituted or unsubstituted C1-20 alkyl group, or substituted or unsubstituted C4-12 aromatic group, characterized by comprising subjecting an ?-aminoacyl acetic acid ester compound of formula (1) wherein R1 and R2 have the same meaning as the above, to hydrogenation by catalytic asymmetric hydrogenation in the presence of an acid.Type: GrantFiled: July 9, 2004Date of Patent: September 21, 2010Assignee: Nissan Chemical Industries, Ltd.Inventors: Yasumasa Hamada, Kazuishi Makino
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Patent number: 7732470Abstract: Derivative compounds of 11-nonyloxy-undec-8(Z)-eonic acid that mimic epoxide metabolites are provided. Also provided are compositions comprising a therapeutically effective amount of the derivative compounds. The present invention further provides methods for the use of such compositions for the treatment of renal or cardiovascular disease and/or related conditions.Type: GrantFiled: February 29, 2008Date of Patent: June 8, 2010Assignees: Medical College of Georgia Research Institute, Board of Regents, The University of Texas SystemInventors: John D. Imig, John R. Falck
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Publication number: 20100105900Abstract: A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: March 9, 2008Publication date: April 29, 2010Inventors: Heinz W. Pauls, Peter Brent Sampson, Bryan T. Forrest, Radoslaw Laufer, Yong Liu, Miklos Feher, Yi Yao, Guohua Pan
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Publication number: 20100063150Abstract: An object of the present invention is to provide an aflatoxin production inhibitor that inhibits aflatoxin production specifically and efficiently, is highly safe, and is practical, and an efficient production method thereof; and a method for controlling aflatoxin contamination that uses the aflatoxin production inhibitor. Specifically, the present invention relates to an aflatoxin production inhibitor that includes at least one of a dioctatin represented by the following formula (I) and a derivative thereof, as an active ingredient: where, in the formula (I), R represents one of hydrogen and a methyl group. The present invention also relates to a method for producing an aflatoxin production inhibitor in which dioctatin is prepared: by a method including culturing a dioctatin-producing microorganism, and at least one of separating and purifying dioctatin from a culture obtained, by centrifugal liquid liquid partition chromatography; or by chemical synthesis.Type: ApplicationFiled: June 13, 2006Publication date: March 11, 2010Inventor: Shohei Sakuda