Plural Rings Containing Patents (Class 568/325)
  • Patent number: 4255434
    Abstract: Fungicidal 1-(azol-1-yl)-4-halo-1-phenoxy-butan-2-ones and -ols of the formula ##STR1## in which R represents alkyl with 1 to 4 carbon atoms;X represents hydrogen, alkyl with 1 to 4 carbon atoms or halogen;Y represents halogen;Z represents halogen, straignt-chain or branched alkyl with 1 to 4 carbon atoms, cycloalkyl with 5 to 7 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, alkoxy with one or 2 carbon atoms, alkylthio with 1 or 2 carbon atoms, alkoxycarbonyl with 1 to 5 carbon atoms in the alkoxy part, amino, cyano, nitro, phenyl or phenoxy substituted with at least one of halogen, amino, cyano, nitro and alkyl with 1 to 2 carbon atoms, phenylalkyl with 1 or 2 carbon atoms on the alkyl part optionally substituted in the alkyl part by alkylcarbonyl with a total of up to 3 carbon atoms and in the phenyl part by halogen, nitro or cyano;n represents 0,1,2 or 3,A is --CO-- or CH(OH)--, andB is --N.dbd. or --CH.dbd., or a salt thereof.
    Type: Grant
    Filed: November 27, 1978
    Date of Patent: March 10, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl Buchel, Paul-Ernst Frohberger, Wilhelm Brandes, Hans Scheinpflug
  • Patent number: 4239767
    Abstract: Diaryloxy-imidazolyl-O,N-acetals of the formula ##STR1## or pharmaceutically-acceptable, nontoxic salts thereof wherein X and Y are each halo, alkyl, alkoxy, haloalkylthio, nitro, amino, alkylamino or dialkylamino;Z is a direct bond, methylene, oxygen, sulphur, sulphonyl, alkoxymethylene or a keto moiety;A is a keto moiety or a moiety of the formula C(OH)R, wherein R is hydrogen or alkyl; anda and b are each integers from 0 to 3;are useful for their antimycotic activity and their sporocidal action.
    Type: Grant
    Filed: November 6, 1975
    Date of Patent: December 16, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl H. Buchel, Wolfgang Kramer, Manfred Plempel
  • Patent number: 4229354
    Abstract: The invention includes novel alkali metal complex compounds (and processes for their preparation) which are useful, inter alia for the hydrogenation of alkali metals at room temperature or below room temperature to form hydrides or nitrides.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: October 21, 1980
    Assignee: Studiengesellschaft Kohle mbH
    Inventor: Borislav Bogdanovic
  • Patent number: 4228105
    Abstract: A process for the production of compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms,R.sub.2 is hydrogen, fluorine, chlorine or bromine, andR.sub.3 is bromine, iodine, isobutyl, tert. butyl, cyclohexyl, cyclohexenyl; or phenyl, optionally substituted by fluorine, chlorine, bromine or alkoxy of 1 to 4 carbon atoms; or a radical of formula II, ##STR2## in which either R.sub.4 and R.sub.5 are the same or different and each signifies alkyl of 1 to 3 carbon atoms,orR.sub.4 and R.sub.5 together signify the radical --(CH.sub.2).sub.n --, in which n is 4 or 5, the radical --CH.sub.2 --CH.sub.2 --0--CH.sub.2 --CH.sub.2 --, the radical --CH.sub.2 --CH.dbd.CH--CH.sub.2 --, or the radical --CH.sub.2 --CH.sub.2 --N(R.sub.6)--CH.sub.2 --CH.sub.2 --, in which R.sub.6 is hydrogen or alkyl of 1 to 3 carbon atoms. Hydroxyketone and hydroxy imine intermediates are also disclosed.The compounds of formula I are known to exhibit anti-inflammatory activity.
    Type: Grant
    Filed: November 27, 1978
    Date of Patent: October 14, 1980
    Assignee: Sandoz Ltd.
    Inventor: Rudiger Jeck
  • Patent number: 4218468
    Abstract: There are provided insecticidal ketones having the general structure: ##STR1## insecticidal compositions containing the ketones and a carrier, and the method of controlling insects with the ketones.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: August 19, 1980
    Assignee: Mobil Oil Corporation
    Inventor: Jill H. Paul
  • Patent number: 4216232
    Abstract: Anti-inflammatory compositions are prepared which comprise a therapeutically effective effective amount of a compound of the formula ##STR1## wherein X is CO; Y is an oxygen atom; the dotted line represents a double bond which is present or absent; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen; and R.sub.3 is phenyl unsubstituted or substituted by 1 or 2 substituents selected from the group consisting of fluorine, chlorine, bromine, methyl, ethyl, methoxyl, ethoxyl, benzyloxyl, hydroxyl, acetoxyl, trifluoromethyl, nitro, amino, acetyl, methylthiol, methylsulphonyl, methylamino and dimethylamino; in combination with a pharmaceutically acceptable carrier. Methods of treating inflammation utilizing the compounds of formula (I) are part of the present invention together with the compounds themselves of the above formula.
    Type: Grant
    Filed: February 17, 1978
    Date of Patent: August 5, 1980
    Assignee: Beecham Group Limited
    Inventors: William G. Cole, Alexander C. Goudie, Carl J. Rose
  • Patent number: 4215044
    Abstract: Process for preparing an organic compound of the formula R.sup.2 R.sup.2 CFC(O)R.sup.3, which process comprises contacting and reacting in a reaction mixture which includes an inert solvent, at a temperature of -40.degree. C. to -100.degree. C., ROF and ##STR1## R is polyfluoroperhaloalkyl of 1-6 carbon atoms or FOCF.sub.2 ; R.sup.1 is hydrocarbyl of 1-6 carbon atoms;each R.sup.2 is selected from H, alkyl of 1-17 carbon atoms, cycloalkyl of 3-6 carbon atoms, aryl, heteroaryl and such alkyl, cycloalkyl, aryl and heteroaryl substituted by halogen or alkoxy of 1-6 carbon atoms;R.sup.3 is selected from H, alkyl and haloalkyl of 1-16 carbon atoms, cycloalkyl of 3-10 carbon atoms, aryl and haloaryl, OSi(R.sup.1).sub.3, OH, NH.sub.2, alkoxy of 1-6 carbon atoms, aryloxy, NHR.sup.1 and NR.sup.1.sub.2 wherein R.sup.1 is alkyl of 1-6 carbon atoms, N-arylamino and nitrogen or sulfur heterocyclic of 4-5 carbon atoms;R.sup.3 and one R.sup.2 taken together is a diradical which with the C.dbd.
    Type: Grant
    Filed: April 23, 1979
    Date of Patent: July 29, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William J. Middleton
  • Patent number: 4212998
    Abstract: The present invention relates to a novel organic compound, 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanol. This compound may be produced by:a. condensing 3-trifluoromethylbenzaldehyde with acetophenone under basic conditions to form a substituted chalcone,b. epoxidation of the substituted chalcone to produce the corresponding epoxide,c. converting the epoxide to a chlorohydrin, andd. catalytic hydrogenolysis of the chlorohydrin to produce a diol and subsequently converting the diol into the corresponding alcohol, 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanol.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: July 15, 1980
    Assignee: Hooker Chemicals & Plastics Corp.
    Inventors: David Y. Tang, Arthur M. Foster
  • Patent number: 4212999
    Abstract: The present invention relates to a novel organic compound, 1-phenyl-3-(3-trifluoromethylphenyl)-1,2-propane diol. This compound may be produced by:(a). condensing 3-trifluoromethylbenzaldehyde with acetophenone under basic conditions to form a substituted chalcone,(b). epoxidation of the substituted chalcone to produce the corresponding epoxide,(c). converting the epoxide to a chlorohydrin, and(d). catalytic hydrogenolysis of the chlorohydrin to produce a diol, 1-phenyl-3-(3-trifluoromethylphenyl)-1,2-propan-diol.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: July 15, 1980
    Assignee: Hooker Chemicals & Plastics Corp.
    Inventors: David Y. Tang, Arthur M. Foster
  • Patent number: 4208425
    Abstract: Beta-diketones substituted by an aryl-aliphatic group in which the aliphatic chain is interrupted by a cyclic group, and useful as anti-viral agents, are prepared by interacting the appropriate aryl-aliphatic halide with an alkali metal salt of a beta-diketone.
    Type: Grant
    Filed: October 10, 1978
    Date of Patent: June 17, 1980
    Assignee: Sterling Drug Inc.
    Inventor: Guy D. Diana