Sulfur, Oxygen, Halogen Or Group Ia Or Iia Light Metal Containing Patents (Class 568/6)
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Publication number: 20100311968Abstract: Organic compounds having t-butyl ester or BOC carbonate protecting groups are effectively deprotected by heating in a fluorinated alcohol solution.Type: ApplicationFiled: June 9, 2010Publication date: December 9, 2010Inventors: Jason Chi-Chung Choy, Saul Jaime-Figueroa
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Patent number: 7847115Abstract: The present invention relates to a process for preparing porous organic frameworks by reaction of a reaction mixture in a liquid phase comprising the appropriate starting compounds in the presence of a nonaqueous organic solvent in the presence of and/or with liberation of water, wherein the latter is withdrawn from the liquid phase of the reaction mixture during the reaction. Here, frameworks having relatively high specific surface areas can be obtained in a reproducible way.Type: GrantFiled: February 8, 2007Date of Patent: December 7, 2010Assignee: BASF AktiengesellschaftInventors: Markus Schubert, Ulrich Mueller, Hendrick Mattenheimer
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Publication number: 20100298609Abstract: The present invention discloses a method for preparing an aromatic boron reagent through Barbier-type reaction, comprising reacting an aromatic halogen compound with a boron compound in the presence of a metal to obtain an aromatic boron reagent, wherein the metal may be or may not be activated by an activator. The method according to the present invention can avoid using expensive and complicated procedures of prior art and hence is efficient and economic.Type: ApplicationFiled: July 27, 2010Publication date: November 25, 2010Applicant: TAMKANG UNIVERSITYInventors: Shih-Yuan Lee, Shu-Fang Chu, Yu-Ting Chang
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Publication number: 20100292508Abstract: Provided is a composition comprising hexagonal boron nitride particles having a surface and a substituted phenyl radical bonded to the surface, the substituted phenyl radical being represented by the structure: where X is a radical selected from NH2—, HO—, R2OC(O)—, R2C(O)O—, HSO3—, NH2CO—, halogens, alkyl or aryl, including substituted aryl; where R1 is hydrogen, alkyl or alkoxy, and R2 is hydrogen, alkyl or aryl, including substituted aryl. A process for preparing the composition is also provided.Type: ApplicationFiled: May 13, 2009Publication date: November 18, 2010Applicant: E. I. DU POND DE NEMOURS AND COMPANYInventor: Govindasamy Paramasivam Rajendran
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Publication number: 20100292504Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.Type: ApplicationFiled: July 30, 2010Publication date: November 18, 2010Applicant: Anacor Pharmaceuticals, Inc.Inventors: Stephen J. Baker, Vincent S. Hernandez, Rashmi Sharma, James A. Nieman, Tsutomu Akama, Yong-Kang Zhang, Jacob J. Plattner, Michael Richard Kevin Alley, Rajeshwar Singh, Fernando Rock
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Publication number: 20100286092Abstract: Disclosed herein are ?-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising ?-aminoboronic acids and methods of use thereof.Type: ApplicationFiled: November 13, 2008Publication date: November 11, 2010Inventors: Christopher J. Burns, Randy W. Jackson, Rajesh Goswami, Hongyu Xu
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Patent number: 7829743Abstract: A novel sulfonium borate complex, which can reduce the amount of fluorine ions produced during thermal cationic polymerization, and realize low-temperature, rapid curing properties in a thermal cationic polymerizable adhesive, is represented by the structure of the following formula (1). In the formula (1), R1 is an aralkyl group and R2 is a lower alkyl group. However, when R2 is a methyl group, R1 is not a benzyl group. X is a halogen atom, and n is an integer of 1 to 3.Type: GrantFiled: March 18, 2008Date of Patent: November 9, 2010Assignees: Sony Corporation, Sony Chemical & Information Device CorporationInventor: Yoshihisa Shinya
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Patent number: 7829742Abstract: The present invention relates to novel boronic acid aryl derivatives which are useful as antitumor/anticancer agents. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good inhibitors of the growth of human breast cancer cells. The present invention also relates to the use of the novel boronic acid aryl derivatives to treat cancer. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of cancer.Type: GrantFiled: December 21, 2004Date of Patent: November 9, 2010Assignee: Johns Hopkins UniversityInventor: Saeed R. Khan
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Publication number: 20100267857Abstract: Provided are a salt compound, cationic polymerization initiator and cationically polymerizable composition, which have a superior acid-generating capacity and high sensitivity, and are free from coloration. The salt compound is represented by the following general Formula (1): (wherein, R01 to R05 each independently represents a group selected from a hydrogen atom, a fluorine atom and —YR group, one of the R01 to R05 being a —YR group and at least two of the R01 to R05 being fluorine atoms; Y represents an oxygen atom or a sulfur atom; R represents a C1-C4 alkyl group; Ctp+ represents a p-valent cation, the p being 1 or 2; and n represents a coefficient required for maintaining electrical neutrality).Type: ApplicationFiled: October 28, 2008Publication date: October 21, 2010Applicant: ADEKA CORPORATIONInventors: Kentaro Kimura, Shohei Fujita, Tomoya Tamachi
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Publication number: 20100261674Abstract: Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors). Disclosed herein are potent inhibitors of FAAH and methods for their use for treating a variety of disorder, including hypertension and cardiac hypertrophy.Type: ApplicationFiled: April 6, 2010Publication date: October 14, 2010Inventors: George Kunos, Alexandros Makriyannis
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Publication number: 20100254903Abstract: Substituted aryl-boron compounds comprising at least one 18F atom, as illustrated by the formula (I), where at least one of Y1 or Y2 is 18F and A1 is a substituted aromatic ring, with G1-5 being, independently, C or N, and where the substitutents of the aromatic ring or polycyclic moiety (other than boron) comprise at least one electron-withdrawing group (EWG), providing that sigma total (?total) for all substituents on the aromatic ring or polycyclic moiety except B is about 0.06 or more when said at least one EWG is positioned ortho to B, or about 0.2 or more when no EWG is positioned ortho to B. The compounds include neutral (N=1) and ionic borate (N=2) embodiments. The compounds are useful as positron emission tomography (PET) imaging agents.Type: ApplicationFiled: July 24, 2008Publication date: October 7, 2010Inventors: David Perrin, Richard Ting, Christopher Overall
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Publication number: 20100226597Abstract: The present application provides a process for the preparation of Bortezomib, its intermediates and process for crystalline forms of Bortezomib.Type: ApplicationFiled: September 12, 2008Publication date: September 9, 2010Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.Inventors: Raghavendracharyulu Venkata Palle, Rajasekhar Kadaboina, Veerendeer Murki, Amarendhar Manda, Nageshwar Gunda, Ramaseshagiri Rao Pulla, Mallesha Hanmanthu, Narasimha Naidu Mopidevi, Suresh Kumar Ramdoss
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Publication number: 20100222301Abstract: The various embodiments herein provide a topical drug composition for the treatment of diabetes-related complications. According to one embodiment herein, the composition comprises of a compound belonging to a group of chemicals containing borates. Boric acid is used as the base material of the drug. Boric acid is dissolved in saline 0.9% or half saline serum or water, distilled water or boiled water to obtain a boric acid solution with given concentration. The best concentration is 3-5% solution. Alcohol at preset concentration is added to the boric acid solution. According to another embodiment, a method is provided for preparing a topical drug composition for the treatment of diabetes-related disorders.Type: ApplicationFiled: May 16, 2010Publication date: September 2, 2010Inventor: Mihan Jafari JAVID
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Publication number: 20100217001Abstract: Disclosed is a commercially advantageous method for producing a pyrazole fused ring derivative (such as a 7-phenylpyrazolo[1,5-a]pyridine derivative).Type: ApplicationFiled: October 17, 2008Publication date: August 26, 2010Inventors: Keizo Sato, Kazumasa Nara, Naoyuki Shimomura
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Publication number: 20100197875Abstract: The present invention relates to white-emitting copolymers which are obtained by a combination of blue-, green- and red-emitting repeating units. The copolymers of the invention display better film formation and an improved efficiency when used in polymeric organic light-emitting diodes compared to materials according to the prior art.Type: ApplicationFiled: March 22, 2010Publication date: August 5, 2010Applicant: Merck Patent GmbHInventors: Aurelie Falcou, Arne Büsing, Susanne Heun, Jürgen Steiger, Anja Gerhard, Niels Schulte, Heinrich Becker
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Publication number: 20100179350Abstract: A polymerizable boric compound for electrochemical devices represented by the formula (1), wherein, B represents a boron atom, Z represents a polymerizable functional group, X represents a divalent C1-12 hydrocarbon group or in the absence of X, Z and B form a direct bond, AO represents a C2-4 oxyalkylene group, m and n are each the number of moles of the oxyalklylene group added and each independently stands for 2 or greater but less than 6, and R1 and R2 each represents a C1-12 hydrocarbon group.Type: ApplicationFiled: March 22, 2010Publication date: July 15, 2010Inventors: Norio IWAYASU, Shin Nishimura, Takefumi Okumura, Tetsuya Itoh, Takeshi Yabe
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Publication number: 20100168476Abstract: Boron chelate complexes of the general formula are described, where X is either —C(R1R2)— or —C(R1R2)—C(?O)—, in which R1, R2 independently of one another denote H, alkyl (with 1 to 5 C atoms), aryl, silyl or a polymer, and one of the alkyl radicals R1 or R2 may be bonded to a further chelatoborate radical, or X denotes 1,2-aryl with up to two substituents S in the positions 3 to 6 in which S1, S2 independently of one another denote alkyl (with 1 to 5 C atoms), fluorine or a polymer, as well as M+ denotes Li+, Na+, K+, Rb+, Cs+ or [(R3R4R5R6)N]+ or H+, where R3, R4, R5, R6 independently of one another denote H or alkyl with preferably 1 to 4 C atoms.Type: ApplicationFiled: December 10, 2009Publication date: July 1, 2010Inventors: Ulrich Wietelmann, Uwe Lischka, Klaus Schade, Jan-Christoph Panitz
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Publication number: 20100160689Abstract: The invention relates to salts having alkoxytris(fluoroalkyl)borate anions which on the one hand are used for the synthesis of ionic liquids, but on the other hand can be employed per se as ionic liquid, and to processes for the preparation thereof.Type: ApplicationFiled: March 2, 2010Publication date: June 24, 2010Inventors: Nikola (Mykola) Ignatyev, Urs Welz-Biermann, Maik Finze, Eduard Bernhardt, Willner Helge
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Publication number: 20100143806Abstract: A mixture of low-acid lithium borate salts and lithium hydride, to methods for producing the same and to the use thereof for battery electrolytes.Type: ApplicationFiled: July 3, 2008Publication date: June 10, 2010Inventors: Rainer Dietz, Ulrich Wietelmann, Uwe Lischka
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Publication number: 20100137249Abstract: The present disclosure encompasses compounds and compositions that are useful as specific AI-2 antagonists for the control of bacterial quorum sensing. Although the AI-2 antagonists according to the present disclosure may not have bactericidal effect, their ability to attenuate virulence, drug resistance, and/or biofilm formation have therapeutic benefits. In addition, the AI-2 antagonists of the present disclosure can also be used as tools to probe bacterial AI-2 functions. The present disclosure also encompasses methods for inhibiting or attenuating microbial virulence, biofilm formation, and drug resistance. The methods are suitable for preventing bacteria from accruing and forming extensive biofilms that may be a health or hygiene hazard or a physical issue, such as in the blockage of water or fuel lines.Type: ApplicationFiled: June 6, 2008Publication date: June 3, 2010Inventors: Binghe Wang, Nanting Ni, Junfeng Wang, Chung-Dar Lu, Han-Ting Chou, Minyong Li, Shilong Zheng, Yunfeng Cheng, Hanjing Peng
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Publication number: 20100127251Abstract: Light emitting devices are described which incorporate, as the light emitting element, a dendrimer of which the constituent dendrons include a conjugated dendritic structure comprising aryl and/or heteroaryl groups connected to each other via bonds between sp2 hybridized ring atoms of said aryl or heteroaryl groups.Type: ApplicationFiled: November 25, 2009Publication date: May 27, 2010Applicants: ISIS INNOVATION LIMITED, THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWSInventors: Paul Leslie Burn, Ifor David Samuel, Shih-Chun Lo
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Patent number: 7687282Abstract: Methods and compositions are provided for determining the potential of a membrane. In one aspect, the method comprises: (a) introducing a first reagent comprising a hydrophobic fluorescent ion capable of redistributing from a first face of the membrane to a second face of the membrane in response to changes in the potential of the membrane, as described by the Nernst equation, (b) introducing a second reagent which labels the first face or the second face of the membrane, which second reagent comprises a chromophore capable of undergoing energy transfer by either (i) donating excited state energy to the fluorescent ion, or (ii) accepting excited state energy from the fluorescent ion, (c) exposing the membrane to radiation; (d) measuring energy transfer between the fluorescent ion and the second reagent, and (e) relating the energy transfer to the membrane potential. Energy transfer is typically measured by fluorescence resonance energy transfer.Type: GrantFiled: September 29, 2006Date of Patent: March 30, 2010Assignee: The Regents of the University of CaliforniaInventors: Roger Y. Tsien, Jesus E. Gonzalez, III
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Patent number: 7683194Abstract: The invention relates to a method for the production of salts of weakly coordinating anions of the type according to the following formula (1), (2) or (3): M[F—X(OR F)m]z (1), M[(FRO)mX—F—X(ORF)m]z (2), M[(FRO)mX—F—X(ORF)n—F—X(ORF)m]z (3), these salts of weakly coordinating anions and use thereof.Type: GrantFiled: October 28, 2004Date of Patent: March 23, 2010Assignee: Universitat FreiburgInventors: Ingo Krossing, Marcin Gonsior, Lutz Muller
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Publication number: 20100056788Abstract: Provided is a fluoroboron compound which is highly safe and stable and is capable of forming a cyclic ether-fused ring by the intramolecular alkoxymethylation reaction, or a salt thereof. The compound can be synthesized by the intramolecular alkoxymethylation reaction of a fluoroboron compound represented by the formula (I) or a salt thereof in the presence of a metal catalyst. (wherein the moiety represented by the formula represents an aromatic ring; L represents a substituent such as a halogen atom; R represents a substituted or unsubstituted alkylene group having 1 or 2 carbon atoms; and M represents an alkali metal cation or the like, with the proviso that L and —R—OCH2BF3M are respectively located on contiguous carbon atoms on the aromatic ring, or in the case of a fused aromatic ring, on two carbon atoms adjacent to one carbon at the fused position).Type: ApplicationFiled: September 11, 2007Publication date: March 4, 2010Inventors: Keigo Tanaka, Norio Murai, Shuji Shirotori, Satoshi Nagao, Yuzu Watanabe
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Publication number: 20100022801Abstract: A novel sulfonium borate complex, which can reduce the amount of fluorine ions produced during thermal cationic polymerization, and realize low-temperature, rapid curing properties in a thermal cationic polymerizable adhesive, is represented by the structure of the following formula (1). In the formula (1), R1 is an aralkyl group and R2 is a lower alkyl group. However, when R2 is a methyl group, R1 is not a benzyl group. X is a halogen atom, and n is an integer of 1 to 3.Type: ApplicationFiled: March 18, 2008Publication date: January 28, 2010Applicant: Sony Chemical & Information Device CorporationInventor: Yoshihisa Shinya
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Publication number: 20100016484Abstract: A process for producing a 1,3,2-dioxaborinane compound of the general formula (I) in which each R individually is selected from the group consisting of H and C1-8-alkyl, by reacting a diol of the general formula (II) HO—CRR—CRR—CRR—OH ??(II) with diborane is performed without using a solvent.Type: ApplicationFiled: July 18, 2008Publication date: January 21, 2010Applicant: BASF SEInventors: Karl Matos, Alex J. Attlesey, David F. Rouda, Stefan Pichlmair
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Publication number: 20100010265Abstract: Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity.Type: ApplicationFiled: September 21, 2009Publication date: January 14, 2010Inventors: Alexander Christian Comely, Marta Marfil Sanchez, Llorenc Rafecas Jane, Xavier Verdaguer Espaulella
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Publication number: 20100010249Abstract: The principal object of the invention is to provide a lithium salt having excellent ion conductivity. The invention solves the problem by providing a lithium salt having a structure represented by the general formula (1): in which “M” represents B, Si, Ge, P, As or Sb; “X” represents the valence of “M”; “R1” represents —CmH2m— whereupon “m” is an integer of 1 to 4; “R2” represents —CkH2k+1 whereupon “k” is an integer of 1 to 8; and “n” represents 0 to 12.Type: ApplicationFiled: September 13, 2007Publication date: January 14, 2010Inventors: Tatsuo Fujinami, Ruoyuan Tao, Masaki Matsui
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Publication number: 20100009202Abstract: A stain inhibitor, which acts to neutralise the alkali leached to the surface of a sheet of glass in the presence of water, is disclosed. The stain inhibitor comprises a compound that reacts with the water to produce an acid. The acid acts to neutralise the alkali leached to the surface of the glass. Preferably, the compound hydrolyses to produce the acid, and is an ester.Type: ApplicationFiled: November 2, 2006Publication date: January 14, 2010Inventor: Paul Holmes
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Patent number: 7635595Abstract: The spectroscopic and photophysical properties of fluorescent probes comprising donor-acceptor derivatives comprising the boric acid group or a derivative of boric acid, B(OH)3 (or borate ion, BO(OH)2?1), arsenious acid, H3 AsO3 (or arsenite ion, H2AsO3?1), telluric acid, H6TeO6 (or tellurate ion, H5 TeO6?1) or germanic acid, Ge(OH)6 (or germanate ion, GeO(OH)3?1) are described. Method of using said probes are also provided.Type: GrantFiled: March 10, 2005Date of Patent: December 22, 2009Inventors: Joseph R. Lakowicz, Nicolas Dicesare
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Publication number: 20090239824Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.Type: ApplicationFiled: November 13, 2008Publication date: September 24, 2009Applicant: Anacor Pharmaceuticals, Inc.Inventors: Ving Lee, Jacob J. Plattner, Stephen J. Benkovic, Stephen J. Baker, Kirk R. Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio A. Sauro
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Patent number: 7586015Abstract: A process is used for the preparation of 1,3,2-oxazaborolidine compounds. This process prepares compounds of formula (I) or (IA): in which: R1 is an alkyl or an aryl; and R2, R3, R4 and R5 are especially a hydrogen atom or an alkyl, wherein the following are reacted in two steps: a) a boric precursor compound with an acetal compound to give a boronate compound; and b) the boronate compound with an amino alcohol compound. This process avoids by-products and exhibits a very good stereospecificity.Type: GrantFiled: January 25, 2007Date of Patent: September 8, 2009Assignee: Zach SystemInventors: Alain Burgos, Stëphane Frein
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Publication number: 20090221527Abstract: The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-? mediated conditions.Type: ApplicationFiled: January 31, 2006Publication date: September 3, 2009Applicants: CEPTION THERAPEUTICS, INC., TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAInventors: Mark I. Greene, Ramachandran Murali, Xin Cheng, Raphael Ottenbrite, Yingxin Xiao
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Publication number: 20090209492Abstract: The present invention relates to inhibitors of lipases, such as inhibitors of endothelial lipase, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. The prototype of these inhibitors has lipophilic portion and an electrophilic site.Type: ApplicationFiled: November 14, 2005Publication date: August 20, 2009Applicant: TRUSTEES OF TUFTS COLLEGEInventors: William W. Bachovchin, Hung-Sen Lai, Daniel Philip O'Connell
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Patent number: 7572458Abstract: Provided are a boron compound-layered double hydroxide (LDH) nanohybrid in which a boron compound for boron neutron capture therapy is intercalated in between layers of LDH, a method of preparing the boron compound-LDH nanohybrid, and a pharmaceutical composition including the boron compound-LDH nanohybrid, which can be used in boron neutron capture therapy.Type: GrantFiled: June 11, 2008Date of Patent: August 11, 2009Assignee: Ewha University-Industry Collaboration FoundationInventors: Jin Ho Choy, Ie Rang Jeon, Soo Jin Choi, Jae Min Oh
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Patent number: 7572541Abstract: A fuel cell comprises a unit cell having a membrane-like electrode unit including an electrolyte membrane, a fuel electrode consisting essentially of a catalyst layer and a diffusion layer, which are formed in the order mentioned on one surface of the electrolyte membrane, and an air electrode consisting essentially of a catalyst layer and a diffusion layer, which are formed in the order mentioned on the other surface of the electrolyte membrane. The diffusion layer of at least the fuel electrode includes a carbon paper prepared by laminating carbon fibers, and a specified water repellent polymer is arranged to cover the surface of the carbon fiber of the carbon paper or is loaded in the clearance among the carbon fibers.Type: GrantFiled: November 22, 2005Date of Patent: August 11, 2009Assignee: Kabushiki Kaisha ToshibaInventor: Tomoaki Arimura
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Publication number: 20090182172Abstract: The present invention discloses a new class of triarylsulfonium salt photoacid generators (PAGs), which are thermally stable and can be activated by long wavelength UV or visible light. The sulfonium PAGs of the present invention are additionally soluble in monomers that can be polymerized by cationic polymerization chemistry, and mixtures of said sulfonium PAGs and monomers can be stored for long periods of time without undergoing polymerization. Furthermore, typical holographic recording media comprising one of these sulfonium PAGs, polymerizable monomer(s), a sensitizing dye, and a binder can be stored for long periods of time without exhibiting significant loss of recording sensitivity. Preferred sulfonium PAGs of the present invention are sulfonium PAGs substituted with one or more fluoro or fluoroalkyl groups.Type: ApplicationFiled: August 4, 2008Publication date: July 16, 2009Inventors: Eric S. Kolb, Erdem A. Cetin, Kirk D. Hutchinson, Richard A. Minns
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Patent number: 7560219Abstract: Sulfonium salt photoinitiator compositions, precursors useful in the preparation of such photoinitiators and the use of these photoinitiators in, e.g., UV curable adhesives, UV curable sealants, UV curable coating compositions, such as printing inks and varnishes, and UV curable encapsulants.Type: GrantFiled: April 26, 2007Date of Patent: July 14, 2009Assignee: Henkel AG & Co. KGaAInventors: Yuxia Liu, Donald E. Herr
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Patent number: 7553924Abstract: The present invention mainly relates to a carbon-carbon bond formation catalyzed by a complex comprising a novel and stable ligand and a metal center. The ligand uses a ring, particularly a phenyl group, or a hydrocarbon group to link an amino group and PR1R2, NR1R2, OR1, SR1, or AsR1R2 group for stabling the structure of the ligand.Type: GrantFiled: June 23, 2004Date of Patent: June 30, 2009Assignee: National Sun Yat-Sen UniversityInventor: Lan-Chang Liang
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Publication number: 20090143586Abstract: The invention relates to a method for producing alkyl-substituted aromatic and heteroaromatic compounds by cross-coupling alkyl boronic acids with aryl- or heteroaryl-halogenides or with aryl- or heteroaryl-sulfonates in the presence of a catalyst and of a Brönsted base in a solvent or solvent mixture.Type: ApplicationFiled: March 7, 2006Publication date: June 4, 2009Inventors: Stefan Scherer, Andreas Meudt, Sven Nerdinger, Bernd Wilhelm Lehnemann, Thomas Jagusch, Victor Snieckus
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Publication number: 20090134369Abstract: Compounds, synthesis of, and methods for synthesizing metal alkoxide derivatives; and metal alkoxide derivatives for use as flame retardants are described. Group 13 metal alkoxides having flame retardant properties may be prepared by reacting the group 13 metal trihydroxide with an alcohol.Type: ApplicationFiled: October 31, 2008Publication date: May 28, 2009Applicant: APPLIED NANOWORKS, INC.Inventors: Partha S. Dutta, Sarah L. Lewis, Kyle E. Litz, Mark N. Rossetti, Tracey M. Jordan, Jennifer L. Vreeland
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Patent number: 7527899Abstract: Orthoborate salts suitable for use as electrolytes in lithium batteries and methods for making the electrolyte salts are provided. The electrolytic salts have one of the formulae (I). In this formula anionic orthoborate groups are capped with two bidentate chelating groups, Y1 and Y2. Certain preferred chelating groups are dibasic acid residues, most preferably oxalyl, malonyl and succinyl, disulfonic acid residues, sulfoacetic acid residues and halo-substituted alkylenes. The salts are soluble in non-aqueous solvents and polymeric gels and are useful components of lithium batteries in electrochemical devices.Type: GrantFiled: June 18, 2001Date of Patent: May 5, 2009Assignee: Arizona Board of Regents for and on behalf of Arizona State UniversityInventors: Charles Austen Angell, Wu Xu
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Patent number: 7514563Abstract: A process for producing cyano substituted arene boranes is described. The compounds are useful intermediates to pharmaceutical compounds using the cyano group as a reactant.Type: GrantFiled: June 8, 2006Date of Patent: April 7, 2009Assignee: Board of Trustees of Michigan State UniversityInventors: Milton R. Smith, III, Robert E. Maleczka, Ghayoor A. Chotana
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Publication number: 20090082561Abstract: The present invention provides methods for preparing complexed diaryl boronic acids from alkyl diarylborinates.Type: ApplicationFiled: July 18, 2008Publication date: March 26, 2009Inventors: Ali Tavassoli, Stephen J. Benkovic
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Publication number: 20090082568Abstract: In a process for the accelerated reduction of organic substrates, selected from the group consisting of ester, amides, nitriles, acids, ketones, imines or mixtures thereof, the substrates are reacted with an amine borane, sulfide borane or ether borane complex as a borane source in the presence of organic accelerator compounds containing both Lewis acidic and Lewis basic sites in their structure, of which the Lewis acidic site can coordinate with the carbonyl or nitrile or imine group of the substrate and the Lewis basic site can coordinate with the borane.Type: ApplicationFiled: September 21, 2007Publication date: March 26, 2009Applicant: BASF AktiengesellschaftInventor: Elizabeth Burkhardt
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Publication number: 20090069520Abstract: Provided is a method for polymerizing a polymer precursor, comprising: contacting a polymer precursor with a lithium carborane catalyst and an initiator under polymerizing conditions. A reaction solvent may be used, but is not necessary. Also provided is a method of preparing lithium carborane polymers, comprising: contacting a lithium carborane polymer precursor having a terminal alkenyl or alkynyl group with an initiator and an optional reaction solvent under polymerizing conditions. Functionalized carborane anions are also provided.Type: ApplicationFiled: August 4, 2006Publication date: March 12, 2009Inventors: Josef Michel, Kamesh Vyakaranam, Stefanie Korbe
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Publication number: 20090036628Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?zHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1 , 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFwRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.Type: ApplicationFiled: January 5, 2007Publication date: February 5, 2009Inventors: Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
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Publication number: 20090036622Abstract: Luminescent polymers having sterically twisted arylene repeat units are provided, which are particularly suited as electroluminescent polymers. Monomers necessary for the synthesis of the sterically twisted polyarylene are provided, as are electroluminescent device utilizing these polymers.Type: ApplicationFiled: February 22, 2006Publication date: February 5, 2009Applicant: SUMATION CO. LIMITEDInventors: Matthew L. Marrocco, Virgil J. Lee, Farshad J. Motamedi
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Publication number: 20090030238Abstract: A protected organoboronic acid includes a boron having an sp3 hybridization, a conformationally rigid protecting group bonded to the boron, and an organic group bonded to the boron through a boron-carbon bond. A method of performing a chemical reaction includes contacting a protected organoboronic acid with a reagent, the protected organoboronic acid including a boron having an sp3 hybridization, a conformationally rigid protecting group bonded to the boron, and an organic group bonded to the boron through a boron-carbon bond. The organic group is chemically transformed, and the boron is not chemically transformed.Type: ApplicationFiled: November 8, 2007Publication date: January 29, 2009Inventors: Martin D. Burke, Eric P. Gillis, Suk Joong Lee, David M. Knapp, Kaitlyn C. Gray
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Publication number: 20090012044Abstract: The present invention provides novel HIV protease inhibitors containing substituted borane, carborane or metallacarborane clusters with 6 to 12 boron atoms in each cluster. The charge of each borane, carborane or metallacarborane cluster is 0, ?1 or ?2. The number of borane, carborane or metallacarborane clusters in the inhibitor molecule is 1 to 9, and the carborane clusters in metallacarborane inhibitors are coordinated to transition metal atom, selected from the group containing cobalt, iron, nickel and ruthenium. In the cluster, heteroatoms can be present, such as nitrogen, phosphorus, silicon, germanium, tin and sulphur. The present invention covers pharmaceutical compositions containing these inhibitors and their use, both in vitro and in vivo. They are characterized by high effectiveness and stability.Type: ApplicationFiled: January 27, 2005Publication date: January 8, 2009Applicants: VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE, USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CZ, USTAV ANORGANICKE CHEMIE AV CZ, DEPARTMENT OF VIROLOGY, UNIVERSITY OF HEIDELBERGInventors: Vladimir Kral, Petr Cigler, Jan Konvalinka, Milan Kozisek, Jana Prejdova, Bohumir Gruner, Jaromir Plesek, Martin Lepsik, Jana Pokorna, Hans-Georg Krausslich, Jochen Bodem