Acyclic Polycarbon Hydrocarbyl Group Bonded Directly To The Benzene Ring Patents (Class 568/780)
  • Publication number: 20150148430
    Abstract: The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I): wherein R2, R4, & R5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.
    Type: Application
    Filed: November 24, 2014
    Publication date: May 28, 2015
    Inventors: Max Baker, Rajesh Kumar Mishra, John J. Talley, Eduardo J. Martinez
  • Publication number: 20150065756
    Abstract: A straight-chain unsaturated hydrocarbon group having equal to or more than 10 carbon atoms is bonded to at least one or more of meta positions of all of phenol structure units.
    Type: Application
    Filed: May 29, 2013
    Publication date: March 5, 2015
    Applicant: SUMITOMO BAKELITE CO., LTD.
    Inventor: Yuji Suzuki
  • Publication number: 20140100290
    Abstract: A method of treating a prostate cancer condition in a mammal in need of such treatment is disclosed. The method comprises administrating to the mammal an anti-prostate cancer effective amount of a compound of a plant essential oil.
    Type: Application
    Filed: March 8, 2013
    Publication date: April 10, 2014
    Inventor: Jerome Rosenstock
  • Patent number: 8685887
    Abstract: The present application relates to surfactant compositions comprising a) at least one phosphated arylphenol alkoxylate surfactant having an average degree of alkoxylation of from 4-8; and b) at least one alkylamine alkoxylate surfactant having an average degree of alkoxylation of from 2-12 and to the use of these compositions in pesticide formulations comprising solid or encapsulated pesticidally active ingredients or formulation aids and methods for improving the re-suspension properties of pesticide suspensions.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: April 1, 2014
    Assignee: Syngenta Crop Protection LLC
    Inventors: Randall Charles Cush, Sarah Beth Cush, Michael James Hopkinson, Jason Keiper
  • Publication number: 20130316938
    Abstract: Provided is class of compounds of formula (I) wherein X, R1, R2 and R3 have the same meaning as given in the specification capable of releasing fragrant compounds in a controlled manner into the surroundings.
    Type: Application
    Filed: December 23, 2011
    Publication date: November 28, 2013
    Applicant: GIVAUDAN S.A.
    Inventors: Corinne Baumgartner, Felix Flachsmann, Philip Kraft
  • Patent number: 8575400
    Abstract: A (?)-stereoisomer of formula (I): wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful in the treatment or prevention of nausea and vomiting or for promoting an antiemetic effect.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: November 5, 2013
    Assignee: Signature Therapeutics, Inc.
    Inventor: Thomas E. Jenkins
  • Publication number: 20130225855
    Abstract: This specification discloses an operational continuous process to convert lignin as found in ligno-cellulosic biomass before or after converting at least some of the carbohydrates. The continuous process has been demonstrated to create a slurry comprised of lignin, raise the slurry comprised of lignin to ultra-high pressure, deoxygenate the lignin in a lignin conversion reactor over a catalyst which is not a fixed bed without producing char. The conversion products of the carbohydrates or lignin can be further processed into polyester intermediates for use in polyester preforms and bottles.
    Type: Application
    Filed: February 24, 2013
    Publication date: August 29, 2013
    Applicant: Chemtex Italia, S.p.A.
    Inventor: Chemtex Italia, S.p.A.
  • Publication number: 20130225853
    Abstract: This specification discloses an operational continuous process to convert lignin as found in ligno-cellulosic biomass before or after converting at least some of the carbohydrates. The continuous process has been demonstrated to create a slurry comprised of lignin, raise the slurry comprised of lignin to ultra-high pressure, deoxygenate the lignin in a lignin conversion reactor over a catalyst which is not a fixed bed without producing char. The conversion products of the carbohydrates or lignin can be further processed into polyester intermediates for use in polyester preforms and bottles.
    Type: Application
    Filed: February 24, 2013
    Publication date: August 29, 2013
    Applicant: Chemtex Italia, S.p.A.
    Inventor: Chemtex Italia, S.p.A.
  • Publication number: 20130225854
    Abstract: This specification discloses an operational continuous process to convert lignin as found in ligno-cellulosic biomass before or after converting at least some of the carbohydrates. The continuous process has been demonstrated to create a slurry comprised of lignin, raise the slurry comprised of lignin to ultra-high pressure, deoxygenate the lignin in a lignin conversion reactor over a catalyst which is not a fixed bed without producing char. The conversion products of the carbohydrates or lignin can be further processed into polyester intermediates for use in polyester preforms and bottles.
    Type: Application
    Filed: February 24, 2013
    Publication date: August 29, 2013
    Applicant: Chemtex Italia, S.p.A.
    Inventor: Chemtex Italia, S.p.A.
  • Publication number: 20130203984
    Abstract: In a process for oxidizing a hydrocarbon to a product comprising at least one of the corresponding hydroperoxide, alcohol, ketone, carboxylic acid and dicarboxylic acid, the hydrocarbon is contacted with an oxygen-containing compound in at least one oxidation zone in the presence of a catalyst comprising a cyclic imide having an imide group of formula (I): wherein X represents an oxygen atom, a hydroxyl group, or an acyloxy group and wherein the oxygen-containing compound supplied to said at least one oxidation zone has a water content of less than or equal to 0.6% by weight of the oxygen-containing compound.
    Type: Application
    Filed: August 16, 2011
    Publication date: August 8, 2013
    Inventors: Christopher L. Becker, Jihad M. Dakka, Franisco M. Benitez, Edmund J. Mozeleski
  • Patent number: 8486877
    Abstract: An alkylated hydroxyaromatic compound is disclosed which is prepared by reacting at least one hydroxyaromatic compound with at least one branched olefinic propylene oligomer having from about 20 to about 80 carbon atoms in the presence of an acid catalyst, wherein the at least one branched olefinic propylene oligomer is substantially free of any vinylidene content. The alkylated hydroxyaromatic compound has been determined to be substantially free of endocrine disruptive chemicals when the effects were quantified on pubertal development and thyroid function in the intact juvenile female rat.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: July 16, 2013
    Assignee: Chevron Oronite Company LLC
    Inventors: Curtis Bay Campbell, James J. Harrison
  • Publication number: 20130156708
    Abstract: The invention relates to the use of (i) a compound of formula (I) or a (pharmaceutically) acceptable salt thereof or (ii) a mixture comprising one or more or consisting of two or more compounds of formula (I) and/or said salts wherein R1 denotes a radical in ortho-, meta, or para-position to the phenolic OH group, the radical being selected from the group consisting of E/Z-3-methylbut-1-en-1-yl, 3-methylbut-2-en-1-yl and 3-methylbut-3-en-1-yl and R2 denotes a radical in ortho-, meta, or para-position to the phenolic OH group, the radical being selected from the group consisting of H and alkyl groups with 1 to 3 C atoms as antimicrobial agent for inactivation of microorganisms, in particular for rapid inactivation of microorganisms, with the proviso that the use is not within a method for treatment of the human or animal body by surgery or therapy or within a diagnostic method practised on the human or animal body.
    Type: Application
    Filed: October 25, 2012
    Publication date: June 20, 2013
    Applicant: Symrise AG
    Inventor: Symrise AG
  • Patent number: 8455457
    Abstract: Provided herein is a pharmaceutical composition or a kit comprising a combination of a non-selective beta-adrenergic receptor blocker and an adenosine A1 receptor agonist. Also provided herein is a method of reducing intraocular pressure (IOP) in a subject using such a combination or kit. In a particular embodiment, provided herein is a combination of timolol marketed under the brand Timoptic™ and Compound A.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: June 4, 2013
    Assignee: Inotek Pharmaceuticals Corporation
    Inventors: Norman N. Kim, William K. McVicar, Thomas G. McCauley
  • Patent number: 8350097
    Abstract: A (?)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or pro drug thereof, is useful as an anesthetic.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: January 8, 2013
    Assignee: Signature Therapeutics, Inc.
    Inventor: Thomas E. Jenkins
  • Patent number: 8242315
    Abstract: A (+)-stereoisomer of formula (I): wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: August 14, 2012
    Assignee: Singature Therapeutics, Inc.
    Inventor: Thomas E. Jenkins
  • Publication number: 20120196939
    Abstract: A (?)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or pro drug thereof, is useful as an anesthetic.
    Type: Application
    Filed: April 2, 2012
    Publication date: August 2, 2012
    Inventor: Thomas E. Jenkins
  • Patent number: 8173849
    Abstract: A (?)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, is useful as an anesthetic.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: May 8, 2012
    Assignee: Signature Therapeutics, Inc.
    Inventor: Thomas E. Jenkins
  • Publication number: 20120077884
    Abstract: An object of the present invention is to provide: a coccidiosis controlling agent which is excellent in safety, is free of problems such as side-effects, does not cause effect reduction or the like due to the acquisition of resistance to a medicament, and exhibits a high preventive effect and a high treatment effect against coccidiosis; a feed for an animal containing the anticoccidial composition; and a method for raising an animal using the coccidiosis controlling agent and the feed. In order to solve the above-mentioned problem, provided is a coccidiosis controlling agent for an animal, containing heated cashew nut shell liquid and/or cardanol.
    Type: Application
    Filed: June 8, 2010
    Publication date: March 29, 2012
    Inventors: Masami Mochizuki, Kyo Nagashima, Chie Hikita
  • Publication number: 20120035271
    Abstract: A (?)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.
    Type: Application
    Filed: October 14, 2011
    Publication date: February 9, 2012
    Inventor: Thomas E. Jenkins
  • Patent number: 8071818
    Abstract: A (?)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: December 6, 2011
    Assignee: PharmacoFore, Inc.
    Inventor: Thomas E. Jenkins
  • Publication number: 20110118160
    Abstract: An alkylated hydroxyaromatic compound is disclosed which is prepared by reacting at least one hydroxyaromatic compound with at least one branched olefinic propylene oligomer having from about 20 to about 80 carbon atoms in the presence of an acid catalyst, wherein the at least one branched olefinic propylene oligomer is substantially free of any vinylidene content. The alkylated hydroxyaromatic compound has been determined to be substantially free of endocrine disruptive chemicals when the effects were quantified on pubertal development and thyroid function in the intact juvenile female rat.
    Type: Application
    Filed: November 18, 2009
    Publication date: May 19, 2011
    Applicant: Chevron Oronite Company LLC
    Inventors: Curtis Bay Campbell, James J. Harrison
  • Publication number: 20100292346
    Abstract: A (?)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 18, 2010
    Inventor: Thomas E. Jenkins
  • Patent number: 7828991
    Abstract: This invention relates to novel polyether polyols which are prepared by alkoxylation of renewable resource materials, and particularly cashew nutshell liquid (CNSL), and to a process for the preparation of these novel polyether polyols. This invention also relates to flexible polyurethane foams prepared from these long chain polyether polyols, and to a process for the production of these flexible polyurethane foams.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: November 9, 2010
    Assignee: Bayer MaterialScience LLC
    Inventors: Jack R. Reese, Micah N. Moore, Don S. Wardius, Stanley L. Hager
  • Patent number: 7781623
    Abstract: A process for the production of a color-stable composition containing cardanol, including (a) subjecting crude, cashew nutshell liquid to distillation to obtain a distillate; (b) reacting the distillate with acetic anhydride to obtain a reaction mixture; and (c) subjecting the reaction mixture to fractional distillation is provided. A method for the production of color-stable phenalkamines, including (a) subjecting crude, cashew nutshell liquid to distillation to obtain a distillate; (b) reacting the distillate with acetic anhydride to obtain a reaction mixture; (c) subjecting the reaction mixture to fractional distillation to obtain a cardanol-containing fractional distillate; and (d) reacting the fractional distillate with an aliphatic amine and formaldehyde to form a color-stable phenalkamine is also provided.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: August 24, 2010
    Assignee: Cognis IP Management GmbH
    Inventors: Setsuo Sato, Wanderson Bueno De Almeida, Ramiro Carielo Bueno, Alexssander Shigueru Araujo
  • Patent number: 7759527
    Abstract: The invention entitled “A Microwave Induced One Pot Process for The Preparation of Arylethenes” provides a method for the preparation of commercially important 2- or 4-hydroxy substituted arylethenes like styrenes or stilbenes in one pot utilizing cheaper substrates in the form of 2- or 4-hydroxy substituted cinnamic acids and their derivatives as well as reagents in the form of base such as sodium hydroxide, potassium hydroxide, lithium hydroxide, sodium bicarbonate, sodium carbonate, potassium bicarbonate, potassium carbonate, ammonium acetate, imidazole, methylimidazole and the combination thereof, with or without solvent such as dimethylformamide, dimethylsulfoxide, ethylene glycol, diethylene glycol, acetonitrile, acetone, methyl imidazoles, ionic liquid, water and the like. The reaction time vary from 1 min-12 hrs and yield of the products from 49-76% depending upon the base, acid, substrate source of heating monomode or multimode microwave or conventional.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: July 20, 2010
    Assignee: Council of Scientific & Industrial Research
    Inventors: Arun Kumar Sinha, Anuj A Sharma, Vinod Kumar
  • Publication number: 20090247758
    Abstract: The present invention relates to a composition for the prevention and treatment of cardiovascular diseases containing the novel quinoline compound, the centipede extracts or compounds isolated from the extracts. The novel quinoline compound, the centipede extracts or a quinoline compound and a phenol compound isolated from the extracts of the invention exhibit excellent LDL-antioxidant activity, ACAT inhibiting activity, and anti-inflammatory activities, so that they can be included as an effective ingredient in a composition for the prevention and treatment of cardiovascular disease including hyperlipidemia, atherosclerosis, coronary heart disease, and myocardial infarction mediated by LDL-oxidation, cholesteryl ester synthesis and accumulation, and inflammation.
    Type: Application
    Filed: May 19, 2006
    Publication date: October 1, 2009
    Inventors: Ho Yong Park, Tae-Sook Jeong, Hyun-Woo Oh, Woo-Song Lee, Doo-Sang Park, Jong-Min Han
  • Patent number: 7528169
    Abstract: A compound represented by the following formula (I) or a salt thereof which has excellent antitumor activity and angiogenesis inhibitory action in a low oxygen condition, and a medicament such as an antitumor agent and an anti-inflammatory agent which comprises the compound or a physiologically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: May 5, 2009
    Assignee: Riken
    Inventors: Hiroyuki Osada, Hideaki Kakeya, Hiroshi Konno, Susumu Kanazawa
  • Publication number: 20090036584
    Abstract: Disclosed is an environmental stress cracking resistance improver that is composed of a compound that has in the molecule thereof a structure represented by the following general formula (I) and a molecular weight of from 200 to 2,000. Also disclosed are a method for improving environmental stress cracking resistance properties that uses the environmental stress cracking resistance improver, and a resin composition with improved environmental stress cracking resistance properties that contains the environmental stress cracking resistance improver. In the above general formula, R1 and R2 are each a hydrocarbon group having 1 to 6 carbon atoms, and may be the same or different from each other.
    Type: Application
    Filed: February 15, 2007
    Publication date: February 5, 2009
    Inventors: Keiko Fukushi, Kenji Iwamasa, Masahiko Okamoto
  • Patent number: 7393465
    Abstract: A process for preparing hydrophobic polyols that includes reacting A) a mixture having an OH content of from 180 to 300 mg KOH/g, a viscosity at 23° C. of from 5000 to 20 000 mPas and an OH functionality of from 2.8 to 4.5 including from 5 to 20 wt. % of 3-pentadecadienylphenol, from 5 to 10 wt. % of 3-pentadecadienyl-recorcinol and from 1 to 5 wt. % of 2-methyl 3-pentadecadienylrecorcinol; with B) alkylene oxides (AO) with addition of the AO monomers onto the AO-reactive groups of component A); the ratio of the amounts of A) to B) being from 1:9 to 9:1; where the hydrophobic polyols have an OH number of from 140 to 220 mg KOH/g and a viscosity at 23° C. of from 1000 to 4000 mPas. The hydrophobic polyols can be used in polyurethane systems, in coatings, adhesive bonds, sealants or moulding compounds, which can be used to coat substrates.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: July 1, 2008
    Assignee: Bayer MaterialScience AG
    Inventors: Meike Niesten, Jack Reese, Joachim Simon, Gerhard Ruttmann
  • Patent number: 7288683
    Abstract: An alkylation method comprises reacting a hydroxy aromatic compound with an alkyl alcohol in the presence of an alkylation catalyst comprising a metal oxide wherein the alkylation catalyst, has a surface area to volume ratio of about 950 to about 4,000 m2/m3, an aspect ratio of about 0.7 to about 1.0 or a combination of the foregoing.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: October 30, 2007
    Assignee: General Electric Company
    Inventors: Hugo G. E. Ingelbrecht, David Parrillo, Mukund Parthasarathy, Gert-Jan Schoenmakers, Geuch Zijlma
  • Patent number: 7244772
    Abstract: We describe a process for the preparation of polyurethane polyol from CARDANOL 3-(8pentadecenyl)phenol, derived from cashew nut shell liquid (CNSL), a renewable resource material. The polyol is made by oxidation with peroxy acid generated in situ to give epoxidised CARDANOL 3-(8-pentadecenyl)phenol and the epoxy derivative is converted to the polyol in the presence of the organic acid. The cardanol-based polyol may be reacted with isocyanate to form polyurethane. Alternatively blowing agents are included with the cardanol-based polyol before it is reacted with the isocyanate. These polyols are especially suitable for making rigid foams of very low density and high compressive strength.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: July 17, 2007
    Assignee: Council of Scientific and Industrial Research
    Inventors: Suresh Kattimuttathu Ittara, Kishanprasad Vadi Sarangapani
  • Patent number: 6989467
    Abstract: The present invention relates to “a microwave induced process for the preparation of 4-vinylphenols or its derivatives” in which commercially important FEMA GRAS approved perfumery and flavouring vinylphenols (i.e. hydroxystyrenes) namely 4-vinylguaiacol (FEMA GRAS No. 2675) and 4-vinylphenol (FEMA GRAS No. 3739) as well as other useful vinylphenols such as 2,6-dimethoxy-4-vinylphenol, 2-hydroxy-4-vinylphenol, 3-hydroxy-4-vinylphenol etc. by condensation of malonic acid and 4-hydroxyphenylaldehydes or its derivatives.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: January 24, 2006
    Assignee: Council of Scientific and Industrial Research
    Inventors: Arun Kumar Sinha, Bhupendra Prasad Joshi, Anuj Sharma
  • Publication number: 20040158104
    Abstract: In a method for the production of o-alkyl phenols by conversion of phenol with an alkanol at elevated temperature in the gas phase in the presence of a metal catalyst, the conversion takes place in at least two stages wherein the alkanol/phenol molar ratio in each reaction stage is set to a value of approximately ≦0.4; a clear increase in the selectivity for the o-alkyl phenol is obtained.
    Type: Application
    Filed: December 11, 2003
    Publication date: August 12, 2004
    Inventors: Jorg Talbiersky, Edgar Fuhrmann, Wolfgang Bruggemann
  • Publication number: 20040158093
    Abstract: A process for preparing an optically active biaryl compound the formula (4): 1
    Type: Application
    Filed: February 10, 2004
    Publication date: August 12, 2004
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Hiroshi Ueda, Isao Kurimoto
  • Publication number: 20030195379
    Abstract: Disclosed are a method of producing p-hydroxyphenylalkanol of formula.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 16, 2003
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventor: Chikara Murakami
  • Publication number: 20030187171
    Abstract: Polyisobutenylphenols are prepared by alkylating an aromatic hydroxy compound with substantially monoethylenically unsaturated and substantially homopolymeric polyisobutenes in the presence of a Lewis acid alkylation catalyst by a process in which the polyisobutenes have a &bgr; double bond content of at least 35 mol %.
    Type: Application
    Filed: March 25, 2003
    Publication date: October 2, 2003
    Inventors: Arno Lange, Hans Peter Rath
  • Patent number: 6541674
    Abstract: A process for condensing at least one carbonyl compound carrying at least one electron-withdrawing group with an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and said condensation is carried out in a basic medium.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: April 1, 2003
    Assignee: Rhodia Chimie
    Inventors: Roland Jacquot, Michel Spagnol
  • Patent number: 6504065
    Abstract: Reaction of a phenol with a metal salt of an alcohol produces a metal phenolate salt of a phenol. When a hindered phenol is used a hindered metal phenolate is produced. Such hindered metal phenolate salts are useful in driving the synthesis reaction of hindered phenol esters and phosphite esters to completion.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: January 7, 2003
    Assignee: General Electric Company
    Inventors: William Palmer Enlow, Gary Vincent Marlin
  • Patent number: 6476277
    Abstract: The present invention relates to a process for preparing hydroxyaromatics by oxidizing aromatics with dinitrogen monoxide in the gas phase in the presence of nanocrystalline zeolites.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: November 5, 2002
    Assignee: Bayer Aktiengesellschafter
    Inventors: Bernd Vogel, Elias Klemm, Mathias Seitz, Jochen Heller, Jörg Reiser
  • Publication number: 20020022750
    Abstract: A method for producing ortho-alkylated phenols comprising reacting phenols represented by the general formula (1) with monohydric or dihydric alcohol in the presence of germanium oxide under conditions in which said alcohol is in the supercritical condition, wherein each of R1, R2, R3, R4 and R5 independently represents a hydrogen atom, or a linear or branched alkyl group having 1 to 10 carbon atoms.
    Type: Application
    Filed: April 18, 2001
    Publication date: February 21, 2002
    Inventors: Tomoyuki Suzuki, Fumisato Goto
  • Patent number: 6333441
    Abstract: A cis-olefin of the formula: R1—CH═CH—R2 is prepared by reducing an alkyne of the formula: R1—C≡C—R2 with formic acid in the presence of a palladium catalyst. R1 and R2 are independently selected from the group consisting of a hydrogen atom, ester group, substituted silyl group, carboxyl group, cyano group, aliphatic C1-C20 hydrocarbon group, and phenyl group. The cis-olefin which is a useful intermediate for the synthesis of fine chemicals is selectively produced in high yields.
    Type: Grant
    Filed: March 4, 1993
    Date of Patent: December 25, 2001
    Assignees: Nissan Chemical Industries, Ltd.
    Inventors: Fumie Sato, Katsuaki Miyaji, Takehiro Amano
  • Publication number: 20010016671
    Abstract: A reduction-treated copper-based catalyst obtained by reducing a copper-based catalyst with hydrogen in the presence of a liquid phase and a process for producing &agr;-phenylethyl alcohol, which comprises hydrogenating acetophenone in the presence of the same.
    Type: Application
    Filed: January 18, 2001
    Publication date: August 23, 2001
    Inventors: Noriaki Oku, Masaru Ishino
  • Publication number: 20010004674
    Abstract: A process for producing an aromatic ring alkylated phenols, wherein said process comprises reacting phenols represented by the general formula (1): 1
    Type: Application
    Filed: December 13, 2000
    Publication date: June 21, 2001
    Inventors: Tomoyuki Suzuki, Fumisato Goto, Kozo Tanaka
  • Patent number: 6242609
    Abstract: A method for manufacturing a color coupler used in a silver halide photographic light-sensitive material using an ammonium trihalide. Said method for manufacturing the color coupler comprising the following step: a step for halogenating a coupling position of a four equivalent coupler using a halogenating agent, wherein said halogenating agent is said ammonium trihalide.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: June 5, 2001
    Assignee: Konica Corporation
    Inventor: Fumio Ishii
  • Patent number: 6191317
    Abstract: Polyalkyl hydroxyaromatics may be prepared from polyalkylenes and hydroxyaromatics in the presence of an acid catalyst and an organic solvent having a boiling point range with an initial boiling point value of below or about the boiling point of the selected hydroxyaromatic reactants and final boiling point of above or equal to about the boiling point of alkylhydroxyaromatic by-product of the reaction. Using this method, accumulation of undesirable alkylhydroxyaromatic by-product/s in a reaction vessel may be minimized, and/or viscosity of polyalkyl hydroxyaromatic product reduced, allowing for increased ease of transfer and transportation.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: February 20, 2001
    Assignee: Huntsman Petrochemical Corporation
    Inventor: Wei-Yang Su
  • Patent number: 6147123
    Abstract: New methods are described for the treatment of viral hepatitis C involving the administration of vitamin E and other compounds with antioxidant properties. Treatment with high doses of vitamin E is effective in treating chronic hepatitis C in patients refractory to interferon. In addition, new methods are described for the treatment of hepatic fibrosis and hepatic conditions manifesting hepatic fibrosis involving the administration of butylated hydroxytoluene and a metabolite of pentoxifylline, 1-[3-carboxypropyl]-3, 7-dimethylxanthine.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: November 14, 2000
    Assignee: The Regents of the University of California
    Inventors: Mario Chojkier, Dennis Carson
  • Patent number: 5886240
    Abstract: The invention relates to a process for preparing aromatic acetylenes of the formula (I): Ar--C.tbd.C--R.sup.8a, where Ar is: ##STR1## by reacting haloaromatics or aryl sulfonates of the formula (II): Ar--X, with monosubstituted acetylenes of the formula (III): Ar--C.tbd.C--R.sup.8a, where Ar is defined above and X is bromine, chlorine or OSO.sub.2 R, in the presence of a palladium compound catalyst of the formula (IV): ##STR2## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 are, independently of one another, hydrogen (C.sub.1 -C.sub.4)-alkyl, (C.sub.1 -C.sub.4)-alkoxy, fluorine, NH.sub.2, NH-alkyl-(C.sub.1 -C.sub.4), N(alkyl).sub.2 -(C.sub.1 -C.sub.4), CO.sub.2 -alkyl-(C.sub.1 -C.sub.4), OCO-alkyl-(C.sub.1 -C.sub.4), or phenyl, or R.sup.1 and R.sup.2, R.sup.2 and R.sup.3, R.sup.3 and R.sup.4, R.sup.5 and R.sup.6, together form an aliphatic or aromatic ring, and R.sup.7, R.sup.8 are (C.sub.1 -C.sub.8)-alkyl, (C.sub.3 -C.sub.
    Type: Grant
    Filed: April 26, 1996
    Date of Patent: March 23, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Matthias Beller, Claus Peter Reisinger, Wolfgang Anton Herrmann
  • Patent number: 5877381
    Abstract: The present invention provides a fluidized bed catalyst for the synthetic reaction of organic compounds which has a reduced catalyst loss. A fluidized bed catalyst for organic compound synthetic reaction, characterized in that 90% or more of the catalyst particles is in the range of 5-500 .mu.m on the weight-based particle size distribution and 90% or more of the 20-75 .mu.m particles has a crushing strength which satisfies the following equation:CS>A.multidot.d.sub..alpha.wherein CS represents a crushing strength ?g-weight/particle!,A represents a constant 0.001,d represents a particle diameter ?.mu.m!, and.alpha. represents a constant 2.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: March 2, 1999
    Assignee: Nitto Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yutaka Sasaki, Hiroshi Yamamoto, Kiyoshi Moriya, Yoshimi Nakamura
  • Patent number: 5811599
    Abstract: A process for the oxidation of hydrocarbons and their derivatives having the general formula RX, wherein R is from n-alkyl, iso-alkyl, benzyl, cyclohexyl, mono, di or tricyclic aryl, or alkenic groups and X is selected from H, OH or Cl to compounds having formula R.sup.1 XY wherein R.sup.1 =(R--H), X has the meaning defined as above and Y=OH; which comprises of reacting the appropriate hydrocarbon or it's derivative of the formula RX where R and X have the meaning given above, with a solution of aqueous hydrogen peroxide at a temperature in the range of 10.degree.-100.degree. C. in the presence of an amorphous titanium-silicate catalyst having molar chemical composition in terms of the anhydrous oxides of TiO.sub.2 : (5-400) SiO.sub.2, having an average micropore radius between 10 and 40 .ANG., an absorption band around 220 nm in the ultraviolet region, a band around 960 cm.sup.-1 in the infrared region, interatomic vectors around 1.6-1.7, 2.7-2.8, 4.1-4.2 and 5.0-5.2 .ANG.
    Type: Grant
    Filed: August 2, 1995
    Date of Patent: September 22, 1998
    Inventors: Keshavaraja Alive, Ramaswamy Arumugamangalam Venkataraman, Ratnasamy Paul
  • Patent number: RE37947
    Abstract: Novel pharmaceutically/cosmetically-active aromatic polyenic compounds have the structural formula (I): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: December 31, 2002
    Assignee: Centre International de Recherches Dermatologiques Galderma
    Inventors: Jean-Michel Bernardon, Phillippe Nedoncelle