Electromagnetic Coil Patents (Class 600/13)
  • Publication number: 20130072746
    Abstract: Energy emitting systems are provided which include an adjustable conductive coil configured to generate a magnetic or electromagnetic field focused on a target nerve. The coil includes a central aperture which may be adjustable between a first configuration and a second configuration having a radius greater than the radius of the first configuration. The adjustable or movable nature of the coil allows the conductive coil to conform to, accommodate, or be positioned on a particular anatomical structure of a patient to position the coil in proximity to the underlying target nerve. In certain embodiments, methods of magnetic induction therapy are provided which include positioning a conductive coil relative to a portion of a patient's body by adjusting the central aperture of the coil such that the coil may conform to, accommodate or be positioned on the portion of the patient's body in proximity to the underlying target nerve.
    Type: Application
    Filed: April 26, 2012
    Publication date: March 21, 2013
    Applicant: EMKINETICS, INC.
    Inventors: Daniel R. BURNETT, Christopher HERMANSON, James H. Ahlman, Bruno Strul
  • Publication number: 20130072747
    Abstract: A device according to some embodiments may include a primary antenna configured to be located external to a subject. The device may also include at least one processor in electrical communication with the primary antenna and configured to receive a condition signal from an implantable device, the condition signal indicative of a precursor to sleep disordered breathing, and cause transmission of a primary signal from the primary antenna to the implantable device, in response to the condition signal, to stimulate at least one nerve in response to the precursor to sleep disordered breathing.
    Type: Application
    Filed: September 28, 2012
    Publication date: March 21, 2013
    Inventor: Adi Mashiach
  • Publication number: 20130066137
    Abstract: Methods and systems for establishing, adjusting, and/or modulating parameters for neural stimulation based, at least in part, on functional and/or structural measurements are disclosed. A method in accordance with one embodiment includes measuring a volume of functionally active neural tissue within a patient's central nervous system both before and after affecting a target neural population of the patient with electromagnetic stimulation. The method further includes controlling at least one signal delivery parameter with which the electromagnetic stimulation is applied to the patient based, at least in part, on the measured difference in the volume of functionally active neural tissue.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 14, 2013
    Inventor: Justin Hulvershorn
  • Patent number: 8391953
    Abstract: Apparatus for driving current in a power circuit of a medical device inserted into a body of a subject includes a power transmitter, which is adapted to generate, in a vicinity of the body, an electromagnetic field having a predetermined frequency capable of inductively driving the current in the power circuit. A passive energy transfer amplifier, having a resonant response at the frequency of the electromagnetic field is placed in proximity to the medical device so as to enhance the current driven in the power circuit by the electromagnetic field.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: March 5, 2013
    Assignee: Biosense Webster, Inc.
    Inventors: Assaf Govari, Michael Levin
  • Patent number: 8388510
    Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.
    Type: Grant
    Filed: July 10, 2011
    Date of Patent: March 5, 2013
    Assignees: Brainsway, Inc., Yeda Research & Development Co. Ltd. at the Weizmann Institute of Science, The United States of America as Represented by the Secretary Department of Health and Human Services
    Inventors: Abraham Zangen, Yiftach Roth, Pedro C. Miranda, David Hazani, Mark Hallet
  • Publication number: 20130053621
    Abstract: A method of increasing bone mass throughout the body of a user. The method may include the steps of obtaining a distributor comprising a plurality of electromagnetic coils, obtaining a controller comprising a processor and a memory device, operably connected to one another, the memory device storing code executable by the processor, selecting a source of electrical current, connecting the source to the controller, and positioning a user proximate the distributor. The method may further include controlling, by the controller in accordance with the code, delivery of electrical current sequentially and exclusively to each coil of the plurality of electromagnetic coils to generate a magnetic field extending into the user.
    Type: Application
    Filed: February 21, 2012
    Publication date: February 28, 2013
    Inventors: Gregory S. Anderson, Pita Witehira, Elizabeth P. Witehira, Evan L. Bydder
  • Publication number: 20130041201
    Abstract: A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system.
    Type: Application
    Filed: July 20, 2012
    Publication date: February 14, 2013
    Applicant: NATIVIS, INC.
    Inventors: John T. Butters, Bennett M. Butters, Patrick Naughton, Miller Puckette
  • Publication number: 20130035538
    Abstract: A portable digital transducer device that is programmable, has high discrimination at low frequency and low intensity, including a modular, portable digital device that generates electromagnetic fields and can be used for many medical applications. The device can be programmed using software in terms of the main parameters thereof (amplitude, waveform, frequency, pulse sequence, positive-negative model, etc.). In addition, the device is completely portable, lightweight and powered by rechargeable batteries. The high degree of modularity of the device allows flexibility in terms of future developments in accordance with new required parameters. The device also enables the synchronous construction of generator arrays for linear and sequential applications. The device has high discrimination at frequencies below 1 milli-Hz and an intensity of 0.001 ?A.
    Type: Application
    Filed: February 9, 2011
    Publication date: February 7, 2013
    Applicant: Pneuma Research S.L.
    Inventors: Ceferino Maestu Unturbe, Frnak Mikuski, Francisco Del Pozoguerrero
  • Patent number: 8364271
    Abstract: According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation in communication with a predetermined site, wherein the site is brain tissue site. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: January 29, 2013
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Dirk De Ridder
  • Publication number: 20130023714
    Abstract: In one embodiment the present invention discloses a nanocluster or a nanorose composition comprising two or more closely spaced nanoparticles each comprising one or more metals, metal oxides, inorganic substances, or a combination thereof and one or more stabilizers. The stabilizers are in contact with the two or more closely spaced nanoparticles to form a nanocluster composition in which the inorganic weight percentage is greater than 50% and the average size is below 300 nm, and the nanocluster composition has magnetic properties, optical properties or a combination of both.
    Type: Application
    Filed: October 26, 2009
    Publication date: January 24, 2013
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS
    Inventors: Keith P. Johnston, Li L. Ma, Marc D. Feldman, Thomas E. Milner, Konstantin V. Sokolov, Jasmine Rowe, Justina Tam, Stanislav Emelianov, Kort Travis, Avinash K. Murthy
  • Publication number: 20130023719
    Abstract: A system for monitoring the use of a home-based medical apparatus providing medical therapy to a patient incorporates communication technology to permit communication from the operated component of the medical apparatus to a central station through one or more of Bluetooth® telephone communications, Smart Phone communications, Internet communications through a network, or other known or forthcoming communication devices. The operated medical apparatus can report any operational function to the central station for monitoring by medical professionals or caregivers, including the timing of any operation of the apparatus, the duration of operation, the effectiveness of the therapy, and malfunctions in the operation of the apparatus. The monitoring system is particularly adapted for use with inflation garment therapy and negative pressure wound therapy systems.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 24, 2013
    Inventor: John A. Bennett
  • Publication number: 20130012759
    Abstract: This invention pertains to a non-contact Qi emission and amplification electronic device. Qi is a Chinese word for the life energy that circulates in human beings. The device is a passive electronic device, that is, it is not powered by any battery or electrical supply. It does not come into contact with the user. The user places the device a few feet away. As such the device is totally safe in terms of dangerous electrical shocks or electromagnetic emissions. The device has a switch to turn it on or off. The switch connects together electronic components, including a piezo-crystal, inside the device. Ambient fluctuations in the voltage of the piezo-crystal may produce an influence field that is broadcasted to an approximately six foot radius surrounding the device. The influence field feels like a cool breeze and affects the user in similar ways to the emitted Qi from Qi Gong practitioners.
    Type: Application
    Filed: July 11, 2012
    Publication date: January 10, 2013
    Inventor: Jack Y. Dea
  • Patent number: 8343027
    Abstract: Methods and devices for providing electromagnetic field treatment to a subject having a metal-containing implant or prosthesis at or near the treatment site. These treatment methods can include calibrating the treatment devices such that the treatment field provided is not distorted or affected by the presence of metal in the target location. Additionally, embodiments of the invention provide for wearable and adjustable electromagnetic treatment devices with reinforcing support members to maintain the structure of flexible metal applicators, which generate the therapeutic electromagnetic field.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: January 1, 2013
    Assignee: Ivivi Health Sciences, LLC
    Inventors: Andre' A. DiMino, Matthew E. Drummer, Arthur A. Pilla
  • Publication number: 20120330090
    Abstract: A portable, non-invasive device for providing therapeutic treatment to a joint to promote healing of the joint includes a cuff positionable around the joint. The cuff includes an electromagnetic stimulator configured to provide an electromagnetic field within the joint and at least one thermal therapy component including an activation circuit configured to activate the electromagnetic stimulator circuit, the thermal therapy component coupleable to the cuff, the thermal therapy component comprising at least two substances in separate compartments separated by a breakable barrier, wherein the at least two substances are configured to react upon mixing to produce thermal energy exchangeable with the joint.
    Type: Application
    Filed: July 3, 2012
    Publication date: December 27, 2012
    Applicant: ORTHOCOR MEDICAL, INC.
    Inventors: Kin-Joe Sham, Jared J. Savela, Kristopher M. Siverhus, John F. Dinusson
  • Publication number: 20120310035
    Abstract: The treatment of specific neurological and psychiatric illnesses using Transcranial Magnetic Stimulation (TMS) requires that specific neuroanatomical structures are targeted using specific pulse parameters. Described herein are methods of positioning and powering TMS electromagnets to selectively stimulate a deep brain target region while minimizing the impact on non-target regions between the TMS electromagnet and the target. Use of these configurations may involve a combination of physical, spatial and/or temporal summation. Specific approaches to achieving temporal summation are detailed.
    Type: Application
    Filed: August 15, 2012
    Publication date: December 6, 2012
    Inventors: M. Bret Schneider, David J. Mishelevich
  • Publication number: 20120302821
    Abstract: In certain variations, systems and/or methods for electromagnetic induction therapy are provided. One or more ergonomic or body contoured applicators may be included. The applicators include one or more conductive coils configured to generate an electromagnetic or magnetic field focused on a target nerve, muscle or other body tissues positioned in proximity to the coil. One or more sensors may be utilized to detect stimulation and to provide feedback about the efficacy of the applied electromagnetic induction therapy. A controller may be adjustable to vary a current through a coil to adjust the magnetic field focused upon the target nerve, muscle or other body tissues based on the feedback provide by a sensor or by a patient. In certain systems or methods, pulsed magnetic fields may be intermittently applied to a target nerve, muscle or tissue without causing habituation.
    Type: Application
    Filed: April 25, 2012
    Publication date: November 29, 2012
    Applicant: EMKINETICS, INC.
    Inventor: Daniel R. BURNETT
  • Publication number: 20120296150
    Abstract: The present invention relates to the electromagnetic field physiotherapy and may be used for treating and preventing various diseases and disorders. A portable apparatus for local integrated electromagnetic irradiation comprises a device for generating a light field with a combinable wavelength, an array of individual light sources with different wavelengths, a controllable magnetic field source including at least one coil and a core made of a ferromagnetic material and a device for controlling and combining the light and magnetic fields.
    Type: Application
    Filed: January 19, 2010
    Publication date: November 22, 2012
    Inventors: Sergey V. Pletnev, Andrey S. Pletnev, Anatoly A. Barsukov, Sergey V. Pletnev
  • Patent number: 8313422
    Abstract: Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: November 20, 2012
    Assignee: Pulse Therapeutics, Inc.
    Inventor: Francis M. Creighton
  • Patent number: 8308627
    Abstract: A medical and recreational device comprises at least two laminas. The laminas comprise sources of magnetic field. The sources of the magnetic field located on one of the laminas faced to another one completely or partially by like and/or unlike magnetic poles and at least one of said laminas configured to be attached to the treated body part.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: November 13, 2012
    Inventor: Walter Friberg
  • Patent number: 8308628
    Abstract: Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: November 13, 2012
    Assignee: Pulse Therapeutics, Inc.
    Inventor: Francis M. Creighton
  • Patent number: 8303479
    Abstract: The invention relates to a biophysiological regulator for therapeutic treatments, including brain stimulation coils (7) which generate current using a microcontroller (11). The invention includes a second microcontroller (16), a liquid crystal display (17), a selector (21) for selecting pre-recorded programs and a connection port (20) for an external device (19) which is provided with a speaker (24) and LEDs that indicate whether or not the battery is charged (18), the regulator is connected (27), an application is underway (26) and the battery is low (25), and an internal program (28) which regulates the frequency and typology of the output wave and the time. The invention also includes a tamper protection system formed by a microcontroller (29) inside a special connector (30) built into the assembly (applicator and cable), in which the internal software of the device reads the serial number located inside the microcontroller of the connector.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: November 6, 2012
    Assignee: Laboratorios BZ I&D, S.L.
    Inventor: Carlos Zapata Perez
  • Patent number: 8303478
    Abstract: Robotized installation for the guided and controlled positioning and movement of a component or an instrument for diagnostic or surgical treatment at or around the head of a patient, whereby the installation includes a robotic device that forms a serial kinematic chain and carries component or instrument at its free and position-controlled end. The robotic device has three kinematic sub-assemblies that are mutually combined in series and include, a first sub-assembly in the form of a rotary-articulation mechanism corresponding to a serial-type, spherical kinematic arrangement with three degrees of freedom, a second sub-assembly in the form of a mechanism with linear translation along an axis, and a third sub-assembly in the form of a second rotary-articulation mechanism, integral with the moving part of the second sub-assembly and also corresponding to a serial-type spherical kinematic arrangement with three degrees of freedom.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: November 6, 2012
    Assignees: Universite de Strasbourg, Centre National de la Recherche Scientifique, Institut National des Sciences Appliquees
    Inventors: Cyrille Lebosse, Pierre Renaud, Bernard Bayle, Michel De Mathelin, Olivier Piccin, Edouard Laroche
  • Publication number: 20120265048
    Abstract: A system for providing treatment signals to a body of an individual includes a magnetic field measurement circuitry for measuring the magnetic field of the body of the individual and providing feedback information responsive thereto. A user interface displays the feedback information and receives a control input. A plurality of energy treatment circuitries each provides treatment energy to the body of the individual responsive to at least one control signal. An application interface applies the treatment energy to the body of an individual. A control block generates the at least one control signal responsive to the control input.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 18, 2012
    Applicant: AVAZZIA, INC.
    Inventors: TERRYL E. BIGGS, KEVIN FRANK, FRANK SKAGGS, TAMMY J. SMITH LAHUTSKY, TIMOTHY B. SMITH
  • Publication number: 20120259156
    Abstract: This document relates to systems and techniques for the treatment of a cardiac arrest victim via electromagnetic stimulation of physiologic tissue.
    Type: Application
    Filed: February 16, 2012
    Publication date: October 11, 2012
    Applicant: ZOLL MEDICAL CORPORATION
    Inventor: Gary A. Freeman
  • Publication number: 20120259205
    Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells. In one embodiment, the method provides a synergetic effect with chemotherapy.
    Type: Application
    Filed: June 19, 2012
    Publication date: October 11, 2012
    Inventor: Gholam A. Peyman
  • Patent number: 8277371
    Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.
    Type: Grant
    Filed: July 10, 2011
    Date of Patent: October 2, 2012
    Assignees: Brainsway, Inc., Yeda Research & Development Co. Ltd. at the Weizmann Institute of Science, The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Abraham Zangen, Yiftach Roth, Pedro C. Miranda, David Hazani, Mark Hallet
  • Publication number: 20120245403
    Abstract: A device includes a therapeutic electromagnetic circuit configured to emit an electromagnetic field upon activation and a resilient shoe insole coating surrounding the therapeutic electromagnetic circuit, in which the therapeutic electromagnetic device has a circuit board, having an electromagnetic field generator thereon, an antenna, coupled to the circuit board and arranged to radiate the electromagnetic field generated by the electromagnetic field generator, a power source, coupled to the electromagnetic field generator via an activator, and the activator, in which the activator, when turned on, is configured to activate the electromagnetic field generator.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: BIOELECTRONICS CORP.
    Inventor: John Martinez
  • Publication number: 20120232330
    Abstract: A device has a voltage source, an electric conductor connected to an electric pole of the voltage source and acting as an electrode, and a substrate arranged in an electromagnetic field which is formed in the vicinity of the electric conductor when the voltage source is active. The substrate is used to receive drugs.
    Type: Application
    Filed: October 13, 2010
    Publication date: September 13, 2012
    Inventor: Bjarne Geiges
  • Patent number: 8265910
    Abstract: Methods and systems for modeling and displaying magnetic field intensities during Transcranial Magnetic Stimulation (TMS) are described, particularly methods and system for modeling and displaying TMS using overlapping magnetic fields to stimulate deep brain regions.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: September 11, 2012
    Assignee: Cervel Neurotech, Inc.
    Inventors: David J. Mishelevich, M. Bret Schneider
  • Publication number: 20120226139
    Abstract: A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles.
    Type: Application
    Filed: April 25, 2012
    Publication date: September 6, 2012
    Inventor: Gholam A. Peyman
  • Publication number: 20120220813
    Abstract: A device for delivering energy to a muscle may include a housing and at least one energy conduit associated with the housing. The at least one energy conduit may be configured to facilitate transfer of energy from an energy source that may be configured to provide energy to muscle within an organ. The device may further include a plurality of needles connected to the at least one energy conduit. Each needle may be configured to pierce tissue. The plurality of needles may include at least one needle configured to deliver energy through an energy emitting portion. The at least one needle may be sized so that when inserted into a wall of the organ, the energy emitting portion may be located within a muscle layer, and such that a majority of energy delivered via the at least one needle may be substantially confined to the muscle layer.
    Type: Application
    Filed: January 25, 2012
    Publication date: August 30, 2012
    Inventor: Sanford LANE
  • Publication number: 20120209054
    Abstract: The invention is directed to a novel method for reducing discomfort caused by transcutaneous stimulation. The novel method includes providing transcutaneous stimulation, reducing the transcutaneous stimulation at a first location, and substantially maintaining the transcutaneous stimulation at a second location. The transcutaneous stimulation may be created by electric and/or magnetic fields. The first location may be relatively proximate to the cutaneous surface and may comprise tissue, nerves and muscle. Also, the second location may be relatively deeper than the first location and include, for example, brain tissue that requires the transcutaneous stimulation for treatment purposes. The invention further may include locating a conductor on a treatment area and/or a transcutaneous stimulation device relative to the first location. In addition, the method may further include adjusting how much the transcutaneous stimulation is reduced at the first location.
    Type: Application
    Filed: January 12, 2012
    Publication date: August 16, 2012
    Applicant: NEURONETICS, INC.
    Inventors: Mark Edward Riehl, Kenneth Marc Ghiron
  • Publication number: 20120197064
    Abstract: Provided is a magnetic stimulation type medicalcare device including a main body for generating a magnetic stimulation and various probes electrically connected to the main body to stimulate a skin of a patient through non-contact deep penetration. The magnetic stimulation type medicalcare device includes a main body for generating a voltage and at least one probe in which a coil for generating a magnetic field from the voltage generated in the main body is built, the at least one probe being electrically connected to the main body.
    Type: Application
    Filed: July 29, 2010
    Publication date: August 2, 2012
    Inventors: Do Guwn Hwang, Syung Hyun Cho, Byung Jae Kim, Sang Dae Choi
  • Publication number: 20120197063
    Abstract: Systems and methods for removing plaque from blood vessels by applying constant or time varying magnetic or electrical fields. In one embodiment a system includes winding configurations positioned about a central axis along which a body region may be placed. Each winding configuration generates a magnetic field in a direction which passes through the body region. A first winding configuration generates a first magnetic field component perpendicular to a second magnetic field component generated by a second winding configuration. In a related method for removing a deposit of plaque from a position along a wall of a blood vessel a magnetic field is applied which has a net direction predominantly orthogonal to the direction of the flow of blood through the vessel.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 2, 2012
    Inventors: Rainer Meinke, Sasha Ishmael
  • Publication number: 20120183534
    Abstract: Apparatuses, compositions and methods for removing cells which interfere with regenerative processes. The apparatuses, compositions and methods selectively kill partially functional and/or non-functional cells versus functional cells while protecting functional proliferative cells to the extent that, upon removal of the killed cells by disintegration or scavenging, functional cells replace the partially- or non-functional cells.
    Type: Application
    Filed: December 21, 2011
    Publication date: July 19, 2012
    Inventor: Lewis Gruber
  • Publication number: 20120184800
    Abstract: Methods and devices for the regulation of gene expression in tissue by applying an electric and/or electromagnetic field generated by specific and selective signals so as to treat diseases, conditions, and/or tissue. Gene expression is the up-regulation or down-regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are described for the regulation of Matrix Metalloproteinase (MMP) protein gene expression in tumor cells of various targeted tissues via the capacitive coupling or inductive coupling (e.g., by electrodes or one or more coils or other field generating devices disposed with respect to the targeted cells) of specific and selective signals to the cells of these tissues, where the resultant electric and/or electromagnetic fields treat diseased or injured tissues.
    Type: Application
    Filed: July 11, 2011
    Publication date: July 19, 2012
    Inventor: Carl T. Brighton
  • Patent number: 8216121
    Abstract: The invention relates to a device for generating a pulsed electromagnetic field with pulse control, wherein the pulses provided by the pulse generator represent periodic pulses having ascending and descending envelope curves with harmonic or anharmonic oscillation profile within the envelope curves, the pulse sequence is in the range of from 1 pulse/20 minutes to 10 pulses/minute, with pulse sequence, pulse function type and electromagnetic flux density being controlled via values which, obtained using non-invasive measuring methods on a target tissue, represent features of the blood microcirculation, with exponential functions as pulse function type being excluded. Greater and longer-lasting improvements of the microcirculation are achieved.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: July 10, 2012
    Inventors: Peter Gleim, Rainer Klopp
  • Patent number: 8214053
    Abstract: To realize a body surrounding solenoid-type body heating device with small coil impedance which can generate a magnetic flux of predetermined density to one part of the living body near the affected area in the solenoid coil, a body heating device 10 includes a cylindrical solenoid coil 17 in which the body can be inserted easily, a high-frequency power supply 11 to drive the solenoid coil, and a body holder 15 which can be inserted easily in the solenoid coil 17. In the body heating device 10, an across-body direction cross section of the solenoid coil 17 has an arched-shape over a half of the solenoid coil 17 in the peripheral direction and a straight-lined shape in the rest, and a secondary solenoid coil 21 with shorter length and coiled more densely than the solenoid coil 17 is inserted in the solenoid coil 17. A magnetic core 40 which can be inserted easily in the solenoid coil 17 is installed on the body holder 15.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: July 3, 2012
    Assignees: Nanotherapy Co., Ltd., Dai-Ichi High Frequency Co., Ltd.
    Inventors: Kotaro Hirayama, Isamu Tomoda, Shuichiro Miyata
  • Patent number: 8212554
    Abstract: A system (100) including a catheter mounted magneto sensor (114), such as a superconducting quantum interference device (SQUID), and methods using the system are disclosed, where the system and method are designed to detect changes in a magnetic field in a body of interest, such as a patient, to detect changes in a magnetic field in a patient, to identify loci in a target body that accumulate magnetic particles or to identify vulnerable plague in a patient.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: July 3, 2012
    Assignees: The University of Houston System, Board of Regents, The University of Texas Systems
    Inventors: Audrius Brazdeikis, Jaroslaw Wosik, Paul Cherukuri, Morteza Naghavi
  • Publication number: 20120149968
    Abstract: Methods and devices are described for the regulation of BMP 2 and 4, TGF-beta 1, 2, and 3, FGF-2, osteocalcin, and alkaline phosphatase mRNA in stem cells via capacitive coupling or inductive coupling of specific and selective electric and/or electromagnetic fields to the bone cells or other tissues containing the stem cells, where the specific and selective fields are generated by application of specific and selective signals to field generating devices disposed with respect to the stem cells so as to facilitate the treatment of diseased or injured bone and other tissues. The resulting methods and devices are useful for the targeted treatment of osteoporosis, osteopenia, osteonecrosis, fresh bone fractures, fractures at risk, nonunion, bone defects, spine fusion, and/or other conditions in which BMP 2 and 4, TGF-beta 1, 2, and 3, FGF-2, osteocalcin, and alkaline phosphatase mRNA and/or protein deficiencies in stem cells has been implicated.
    Type: Application
    Filed: November 23, 2011
    Publication date: June 14, 2012
    Inventor: Carl T. Brighton
  • Publication number: 20120149969
    Abstract: A method and morphologically adaptable apparatus for altering the charge distribution upon living membranes is provided. The method and apparatus further provides a static magnetic device for production of a magnetic field for treatment of various disorders that can be focused at the site of pain or edema to deliver a gradient in the magnetic field to prevent or reduce charge flow. Further there is provided a static magnetic device for production of a magnetic field for treatment of disorders wherein the device provides a static magnetic field such that the focused magnetic field gradient is oriented to be perpendicular to the neuron or membrane charge flow providing maximum deflection of the ion or charge flow.
    Type: Application
    Filed: January 27, 2012
    Publication date: June 14, 2012
    Applicant: GRADIENT TECHNOLOGIES LLC
    Inventor: William Farone
  • Publication number: 20120143043
    Abstract: A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles. The heat (temperature) and photoacoustic sound wave production inside the target tissue is measured. The desired temperature is achieved using a laser and photoacoustic imaging technique. Hyperthermia treatment of tissue applies a heat source to kill cells without protein denaturation. The hyperthermia treatment may further comprise platelet-derived treatment. The method introduces an encapsulated dye that is released at a selected temperature in the target site to indicate that a threshold temperature has been reached to hyperthermally treat the tissue. The temperature to which the target site is treated ranges from about 39° C. to about 58° C., and may last from about 5 seconds to about 30 minutes. The composition which can be a liposome composition encapsulating the dye can be introduced to the bloodstream to flow through the target site.
    Type: Application
    Filed: January 30, 2012
    Publication date: June 7, 2012
    Inventor: Gholam A. Peyman
  • Patent number: 8177702
    Abstract: A proximity sensor for a transcranial magnetic stimulation (TMS) system detects the proximity of a TMS coil assembly to a position at which the coil is to receive pulses during TMS treatment and provides feedback to the operator so that the operator may adjust the TMS coil assembly as necessary to maintain optimal positioning during treatment. A flexible substrate containing a sensor or sensor array is disposed between the TMS coil assembly and the position such that the coupling of the TMS coil assembly to the position may be detected by the sensor(s). Sensor outputs are processed by signal processing circuitry to provide an indication of whether the TMS coil assembly is properly disposed with respect to the position during TMS treatment. A display may be used to provide an indication of how to adjust the TMS coil assembly to improve the positioning of the TMS coil assembly.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: May 15, 2012
    Assignee: Neuronetics, Inc.
    Inventors: Mark Edward Riehl, Kenneth Marc Ghiron, Stanford W. Miller
  • Patent number: 8172742
    Abstract: A magnetic stimulation apparatus for central nervous system and circuit thereof, and use of the apparatus and method of using the apparatus are shown. Controlling circuit design and outputting wave form signal to a drive power supply circuit enables the drive power supply circuit to output current of corresponding wave form to coils, and by means of the design of the shape, number of turns, size, interval of the coils, generates within a certain region inside the coils a desired time-variant magnetic field which is then applied to the brain of an animal or a human being so that the central nervous system can receive a wide area synergy magnetic stimulation with a precise wave form, high frequency or a combination of a plurality of frequency components, thus achieving the treatment of nervous and psychiatric diseases or brain function improvement in combination with behavior guidance, thought guidance, or psychological guidance.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: May 8, 2012
    Inventors: Yunfeng Zheng, Jiang Wang, Lin Xu
  • Patent number: 8157718
    Abstract: The present invention relates to an electric circuit having a transformer capable of functioning as a buffer inductor, and a magnetic stimulator using the transformer. The electric circuit of the present invention includes a power supply unit, and rectification means for rectifying current from the power supply unit. A transformer has an inductor on a primary side connected to the power supply unit. A capacitor is connected to an inductor on a secondary side of the transformer. Reverse flow prevention means is connected in series between the capacitor and the transformer to prevent charges stored in the capacitor from reversely flowing toward the transformer. A discharge inductor receives charges stored in the capacitor as discharge current and forms a magnetic field. First switching means turns on or off flow of the discharge current that flows in one direction. Bypass means causes current to flow in one direction.
    Type: Grant
    Filed: November 26, 2005
    Date of Patent: April 17, 2012
    Assignee: MCube Technology Co., Ltd
    Inventors: Jeong-Han Yi, Jung-Hoe Kim, Soo-Yeol Lee, Min-Hyoung Cho
  • Publication number: 20120083647
    Abstract: This invention concerns a method for altering an individual's level of consciousness by directing stimulation or inhibition to a CNS locus target region in the individual's brain that is responsible for consciousness.
    Type: Application
    Filed: September 28, 2011
    Publication date: April 5, 2012
    Inventors: Harry SCHEININ, Michael ALKIRE, Kimmo KASKINORO, Jaakko LANGSJO
  • Patent number: 8140169
    Abstract: An induction heating apparatus includes a first interventional device and a second interventional device. The first interventional device includes an electrically conductive material. The first interventional device is adapted for implantation inside a body and for receiving an alternating current. The second interventional device comprises a magnetically conductive material. The second interventional device is adapted for implantation inside the body in close proximity to the first interventional device. With both devices placed inside the body, the second interventional device magnetically couples with the first interventional device and the second interventional device generates heat upon the application of the alternating current to the first interventional device thereby heating the body site.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: March 20, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Barry N. Gellman, Jozef Slanda, Kimberly Paddock
  • Patent number: 8140168
    Abstract: A transcutaneous energy transfer system, transcutaneous charging system, external power source, external charger and methods of transcutaneous energy transfer and charging for an implantable medical device and an external power source/charger. The implantable medical device has a secondary coil adapted to be inductively energized by an external primary coil at a carrier frequency. The external power source/charger has a primary coil and circuitry capable of inductively energizing the secondary coil by driving the primary coil at a carrier frequency adjusted to the resonant frequency to match a resonant frequency of the tuned inductive charging circuit, to minimize the impedance of the tuned inductive charging circuit or to increase the efficiency of energy transfer.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: March 20, 2012
    Assignee: Medtronic, Inc.
    Inventors: David P. Olson, Andrew L. Schmeling, Steven J. Nelson
  • Patent number: 8137259
    Abstract: A magnetic method for therapeutic treatment of an animal with a tissue dysfunction using a pair of very low power electromagnetic coils connected to a pulse generator, a kit using the pulse generator connected to a pair of very low power electromagnetic coils, and a pet bed containing the pair of very low power electromagnetic coils and pulse generator. The pulse generator can include a power supply, a bi-directional communication and power port, a microcontroller, a processor, a data storage, computer instructions, transistors, a voltage multiplier, and power supply conduits.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: March 20, 2012
    Assignee: Magnafix, LLC
    Inventors: Robert Glenn Dennis, Paul Edward Kosnik, James Ronald Clark
  • Publication number: 20120065456
    Abstract: The invention includes a method of treating and preventing a neurological disorder, such as Alzheimer's Disease, in a subject in need thereof by positioning an electromagnetic field emitting source proximal to the subject and exposing the subject to an electromagnetic field having a predetermined frequency for a predetermined absorption period. Preferably, each individual treatment (comprising exposure to the predetermined frequency for the predetermined absorption period) is continued at a predetermined schedule (preferably daily) for a predetermined treatment period. The predetermined frequency, according to a preferred embodiment, is about 918 MHz with a specific absorption rate (SAR) of about 0.25 W/kg+/?2 dB. The predetermined absorption period of this preferred embodiment is about one hour. The treatment period is long-term, being greater than about 6 months and preferably between about 7 and 9 months.
    Type: Application
    Filed: September 12, 2011
    Publication date: March 15, 2012
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Gary W. Arendash, Chuanhai Cao, Jun Tan