Abstract: The present disclosure provides devices and methods for improved hemodynamic monitoring, including devices for characterizing hemodynamic activity within a tissue or region of interest.

Abstract: A pulse photometry probe includes a holding member that includes a contact face which is to be in contact with living tissue of a patient, an emitter that is placed in the holding member, a detector that is placed in the holding member and detects light emitted from the emitter, and, a spacer that is disposed between the contact face and the emitter and has an opening, wherein an air layer defined by the opening is disposed between an emitting face of the emitter and the contact face.

Abstract: Embodiments described herein generally relate to devices, methods and systems for determining blood oxygenation. By applying near infrared radiation of an appropriate wavelength to the tissue and determining the absorbance at a plurality of points where the distance between the source of the near infrared radiation and the detector are known, the oxygenation state of the hemoglobin can be determined based on position in a three dimensional space.

Abstract: A smart toothbrush is provided. The smart toothbrush includes a toothbrush head configured to be provided with bristles, a toothbrush body configured to be connected to the toothbrush head and to be able to be held, a temperature sensor configured to measure a temperature within an oral cavity of a user while the user is brushing teeth using the smart toothbrush, and a processor configured to determine a tooth brushing section in which the user is brushing teeth within the oral cavity, based on a temperature value measured by the temperature sensor.

Abstract: Some embodiments relate to a device, method, and/or computer-readable medium storing processor-executable process steps to remove a component of a signal corresponding to ambient light in a photoplethysmographic sensor device, including capturing a first detected light signal representing an ambient light at a first time, causing a light emitter to generate a source light signal driven at a first level, capturing a second detected light signal representing the source light signal after interacting with a user's tissue plus the first detected light signal, generating a first output signal based on the second detected light signal adjusted by the first detected light signal, causing the light emitter to generate a source light signal driven at a second level, capturing a third detected light signal representing the source light signal driven at the second level after interacting with the user's skin plus the first detected light signal, and generating a second output signal based on the third detected light sig

Abstract: According to an embodiment of the present invention, a physical monitoring device is in the form of a necklace or pendant and includes an object (e.g., stone, gem, glass, crystal, or other transparent or translucent object that conveys light signals or color). The physical activity monitoring device includes one or more sensors to measure physical activity or motion of the user (e.g., steps, distance traveled by foot, body motion, etc.). The object is illuminated or changed to different colors to openly and outwardly indicate a level of physical activity of the user.

Abstract: An oximeter includes a main body defining an opening and a finger clamping device arranged in the opening. The finger clamping device includes a shell, an upper clamping member, and a lower clamping member. The shell includes an inner wall carrying a sliding rail. The upper clamping member is arranged in the shell and defines a spindle. A portion of the spindle is received in the sliding rail and can slide along the sliding rail. The lower clamping member faces the upper clamping member and is coupled to the upper clamping member by a torsion spring. A finger being inserted between the upper clamping member and the lower clamping member causes the torsion spring to stretch, the finger is thus clamped by the upper clamping member and the lower clamping member with an elastic restoring force.

Abstract: A reusable sensor is disclosed for producing a signal indicative of at least one physiological parameter of tissue. The sensor can include a sensor housing that has a distal opening, a wire lumen, and a proximal opening. The distal opening can include a lumen extending through the body of the sensor housing and the wire lumen can be located on the outside of the sensor housing. The sensor can also include a first component located on a top surface of the sensor housing and along the pathway of the wire lumen. The sensor can also include a second component located on the bottom surface of the sensor housing opposite of the first component. The second component can also be located along the pathway of the wire lumen. The sensor can also include a wire coaxially disposed within the wire lumen and connecting the first component and second component.

Abstract: A patient monitor can noninvasively measure a physiological parameter using sensor data from a nose sensor configured to be secured to a nose of the patient. The nose sensor can include an emitter and a diffuser. The diffuser is configured to generate a signal when detecting light attenuated by the nose tissue of the patient. An output measurement of the physiological parameter can be determined based on the signals generated by the diffuser.

Abstract: A biopsy device with a hollow shaft is suggested, the shaft having a wall and a distal end portion, wherein a sidewardly facing notch is formed in the distal end portion. At least two optical fibers are arranged in the wall of the shaft so that end surfaces of the fibers are arranged in a longitudinal direction at opposite positions with respect to the notch.

Abstract: Provided according to embodiments of the invention are photoplethysmography (PPG) sensors, systems and accessories, and methods of making and using the same. In some embodiments of the invention, the PPG sensors include a clip body that includes a first end portion and a second end portion; a flex circuit attached or adjacent to the clip body, and an elastomeric sleeve that envelops (1) at least part of the first end portion and at least part of the flex circuit attached or adjacent thereto; or (2) at least part of the second end portion and at least part of the flex circuit attached or adjacent thereto.

Abstract: The invention provides a physiological probe that comfortably attaches to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe, which comprises a separate cradle module and sensor module, secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. The cradle module, which contains elements subject to wear, is preferably provided as a disposable unit.

Abstract: Various sensors and methods of assembling sensors are described. In some embodiments, the sensor assembly includes a first end, a body portion, and a second end. The first end can include a neck portion and a connector portion and the second end can include a flap, a first component, a neck portion, and a second component. A method is also described for sensor folding. The method can include using a circuit with an attached emitter and a detector that is separated by a portion of the circuit. The method can also include folding the portion of the circuit such that a first fold is created through the emitter and folding the portion of the circuit such that a second fold is created such that the first fold and second fold form an angle.

Abstract: A mounting cable includes: a metal cable that includes a core wire formed of a conductive material and a jacket formed of an insulator and covering the core wire; a cable fixing portion that fixes an end portion of the metal cable, and has an end face which is perpendicular to an axial direction of the metal cable and on which a cross section of an end portion of the core wire is exposed; an external connection electrode formed on at least one surface of the cable fixing portion, the at least one surface being in parallel with the axial direction of the metal cable; and a wire pattern that extends from an area on the core wire exposed on the end face to the external connection electrode.

Abstract: Disclosed herein are systems and methods for monitoring one or more of cerebral oxygenation and total hemoglobin concentration that can be used to perform accurate, noninvasive measurement of cerebral venous blood oxygen saturation (oxygenation) in neonatal patients. A neonatal cerebral oxygenation detection apparatus comprises a wearable support having a light emitter and an acoustic sensor coupled thereto. The wearable support can be secured onto a head of an infant, and the light emitter can be configured to emit a light toward a superior sagittal sinus of the infant's head. The acoustic sensor can be configured to detect acoustic pressure generated by blood in the superior sagittal sinus when the superior sagittal sinus blood absorbs the light. Cerebral oxygenation and/or total hemoglobin concentration can be determined based on the acoustic pressure detected by the acoustic detector.

Abstract: A light detection unit includes a light emitter that emits light toward an object of interest, a light receiver that receives light from the object of interest, and a light blocking member that performs light blocking at least above the light receiver. The light blocking member includes a first surface that is provided between the light emitter and the light receiver and prevents direct light from the light emitter from entering the light receiver and a second surface and a third surface that are provided along a direction that intersects the first surface and prevent light from entering the light receiver. Further, the first surface is made of a first material, and the second surface and the third surface are made of a second material different from the first material.

Abstract: An electronic sticker assembly includes a first electronic sticker comprising an upper surface, a lower surface, and a first group of conductive connection dots on the upper surface, a first adhesive layer on the first electronic sticker and comprising a first window. The first window is positioned to expose the first group of one or more conductive connection dots. A second electronic sticker on the first adhesive layer includes a lower surface and one or more second conductive connection dots on the lower surface. The first group of conductive connection dots on the upper surface of the first electronic sticker are in contact with the one or more second conductive connection dots on the lower surface of the second electronic sticker through the first window in the first adhesive layer.

Abstract: Locating systems and methods for components are provided. A component has an exterior surface. A method includes locating a surface feature configured on the exterior surface along an X-axis and a Y-axis by analyzing an image of the component to obtain X-axis data points and Y-axis data points for the surface feature. The method further includes directly measuring the surface feature along a Z-axis to obtain Z-axis data points for the surface feature, wherein the X-axis, the Y-axis and the Z-axis are mutually orthogonal. The method further includes calculating at least two of a pitch value, a roll value or a yaw value for the surface feature.

Abstract: The present invention discloses a non-invasive method of measuring skin thickness and blood glucose concentration of a subject by a Raman system. The advantage of the present invention is that a single Raman spectrum is used to measure both the skin thickness and glucose concentration. The skin thickness and Raman intensity retrieved from the same Raman spectrum are both utilized to yield a more accurate blood glucose concentration. The present invention also discloses a Raman system for measuring physiological data of a subject. It comprises a Raman spectroscopic unit and a signal processing unit.

Abstract: A pulse photometry probe includes: a light emitter having a first face from which light is emitted toward a living body; a light receiver having a second face which receives the light from the living body; a surface sheet which faces the first face of the light emitter and the second face of the light receiver; a cover sheet in which at least one slit is formed; and a lead wire which includes: a first lead wire connected to one of the light emitter and the light receiver; a second lead wire connected to the other one of the light emitter and the light receiver; and a basal portion at which the first lead wire and the second lead wire are bundled. The second lead wire includes at least one slack portion between the basal portion and the other one of the light emitter and the light receiver.

Abstract: The present invention provides a pulse oximeter of the portable type, which is possible to carry around and to use widely regardless of the adult, the infant, the newborn baby, and which can keep the finger still for performing the precise measurement. The pulse oximeter 100 comprises a measurement cavity 110 for accepting the examined portion (for example finger) of the subject, a measurement device 120 including a light emitting part 121 and a photo detecting part 122 facing between the measurement cavity 110, a filling element 140 formed from a material that the light used for the measurement can penetrate. The height and the curvature of the inner surface of the filling element 140 is larger than that of the outer surface of the filling element 140. The filling element 140 converts the height and the curvature of the inner space.

Abstract: A wearable pulse oximetry device and associated methods are provided. In some embodiments, the device includes at least two light sources having different wavelengths and at least one detector responsive to the different wavelengths. The device also includes a structure adapted to fixate at a distal end of the wearer's ulna bone at a fixated area. The light sources having different wavelengths and the at least one detector are fixed within, or adjacent to, the structure such that when the structure fixates at the fixated area the light sources and the at least one detector are positioned adjacent to the distal end of the ulna, and the at least one detector is positioned to detect light emitted from the at least two light sources.

Abstract: Methods for heart rate measurement based on pulse oximetry are provided that can tolerate some degree of relative displacement of a photoplethysmograph (PPG) heart rate monitor device. In some methods, artifact compensation based on a reference signal is performed on the PPG signal data to remove artifacts in the signal that may be caused, for example, by changes in ambient light and/or motion of a person wearing the monitor device. The reference signal used for artifact compensation may be generated using an LED of a complementary wavelength to that of the LED used to generate the PPG signal, or by driving an LED at a lower current than the current applied to generate the PPG signal.

Abstract: Provided is a watch-type terminal including: a main body that includes an antenna module which transmits and receives a wireless signal in a predetermined frequency band; a band that extends from the main body and that is formed in such a manner that the main body is removably worn on a wrist; a ground portion that includes first and second metal members that extend to have different lengths; a sensing unit that detects whether or not the main body is worn on the wrist; and a controller that grounds the antenna module to at least one of the first and second metal members, based on whether or not the main body is worn on the wrist.

Abstract: Disclosed is a picture interaction method, which includes: setting a corresponding relation between a picture material moving speed and a user heartbeat frequency; presenting a picture material; shooting a user body image group, analyzing the user body image group so as to monitor a blood color difference, and calculating a user heartbeat frequency according to the blood color difference; and determining a picture material moving speed corresponding to the user heartbeat frequency according to the calculated user heartbeat frequency, and controlling moving of the picture material based on the determined picture material moving speed.

Abstract: The present invention discloses a lighting effect-controllable computer case, which comprises a computer case containing electrically-connected computer components, including a motherboard and a power source; a lighting controller electrically connected with the motherboard disposed inside the computer case; and at least one LED light strip disposed inside or outside the computer case, electrically connected with the lighting controller, including a plurality LEDs, and presenting different lighting effects according to at least one control signal generated by the lighting controller.

Abstract: A physiological signal collection unit is for use with a physiological signal measuring apparatus to measure physiological signals from an anatomical part of a test subject, in which the anatomical part is covered with hair. The physiological signal collection unit includes a detector and a wearable member. The detector includes a circuit substrate defining a substrate-through-hole to permit hair strands to extend through, an electrical connector, and at least one signal collecting component. The wearable member is to be worn on the anatomical part of the test subject, and is formed with a through-hole having a size smaller than size of the circuit substrate. The through-hole permits the hair strands extending through the circuit substrate to extend through the wearable member.

Abstract: A patient interface for a reusable optical sensor, the patient interface including a compliant element defining a pocket having a lower wall defining an opening therethrough, the pocket being configured to removably receive the reusable optical sensor. The compliant element includes a first wing and a second wing configured for conformal placement on a patient's body. A condition of a patient may be monitored by inserting an optical sensor into a patient interface, applying the patient interface to the patient, obtaining a measurement with the optical sensor related to the condition of the patient, removing the patient interface from the patient, and removing the sensor from the patient interface.

Abstract: A measurement device is provided for measuring a vessel pulse signal of a specific position attached by a mark. The measurement device includes a sensor, a plurality of conductive dots, a determination unit, and a measurement unit. The conductive dots are located around the sensor. The determination unit determines whether the plurality of conductive dots are connected to each other through the mark to generate a determination signal to indicate whether the sensor has been disposed in the specific position.

Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.

Abstract: Disclosed is a fingerstall oximeter including a soft gum coat and a case, a display screen for displaying measurement results is provided on the upper part of the case and an open corresponding to the display screen is provided on the soft gum coat. The soft gum coat is slipped over the outside of the case, the case is used to accommodate and protect a circuit board, and a chamber for accommodating finger is formed and rounded by the upper part of the case and the bottom of the soft gum coat, for accommodating a finger to be measured. A first measurement module is provided on the bottom of the soft gum coat and a second measurement module is provided within the case at a position corresponding to the first measurement module.

Abstract: For repeatedly measuring signals from a fixed position of a tissue to monitor the blood composition, a subject adaptor is used to secure the subject position and a position fixing device uses a remote sensing tool to detect the subject position. The subject adaptor and the position fixing device are used to guide the moving of the subject relative to a position of the last measurement of a first signal analyzer. The signals can be from an aggregate of the designated composition with the other ingredients of the blood.

Abstract: A pacifier is presented including a nipple configured to receive a plurality of breath and saliva samples from a user, a base portion configured for attachment to the nipple, and an output mechanism attached to the base portion and configured for displaying different nutritional information values. The output mechanism may include one or more removable strips. The plurality of breath and saliva samples received from the user via the nipple are analyzed for nutritional information, preferably, continuously and in real-time, and the nutritional information includes at least one of carbohydrates, fats, minerals, protein, fiber, vitamins, water, salt, sugar, sodium, antioxidants, and phytochemicals.

Abstract: Apparatus is provided for detecting an analyte, configured to be implanted in a body of a subject. The apparatus includes an optical fiber having a distal portion and also a membrane permeable to the analyte. The membrane is coupled to the distal portion of the fiber and surrounding a sampling region at least in part, by being fitted over the distal portion of the fiber. Other embodiments are also described.

Abstract: A sensor attached to a living body includes a sensor body that outputs a signal corresponding to biological information, and a cable that is connected to a sensor body and transmits the signal. The cable has a first portion having a first flexibility and a second portion having a second flexibility lower than the first flexibility. The second flexibility enables the second portion to be bent, and is able to retain a shape of the second portion in a bent state.

Abstract: A method for manufacturing a sensor is provided. The method includes providing a frame having a loop structure, and covering the frame with a coating material to provide a sensor body having at least one diaphragm structure. The one or more diaphragm structures of the sensor body bias an emitter housing and a detector housing of the frame toward one another. The sensor may be placed on a patient's finger, toe, and so forth, to obtain pulse oximetry or other physiological measurements.

Abstract: A continuous analysis apparatus capable of transmitting information about components in body fluid to another apparatus such as medicine dosing apparatus more correctly without giving a user displeasure. The continuous analysis apparatus according to the present invention includes a sensing unit 2 including a sensor that is held in subcutaneous tissue for obtaining information with respect to an objective substance in a sample; and a data holding unit 3 having a storage means for storing the information obtained from the sensor or data corresponding to the information, the sensing unit and the data holding unit having configuration so that they are separably joined to each other.

Abstract: A sensor cartridge according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor. Certain embodiments of the sensor cartridge protect the sensor from damage, such as damage due to repeated use, reduce the need for sensor sanitization, or both. Further, embodiments of the sensor cartridge are positionable on the user before insertion in the sensor and allow for improved alignment of the treatment site with the sensor. In addition, the sensor cartridge of certain embodiments of the disclosure can be configured to allow a single sensor to comfortably accommodate treatment sites of various sizes such as for both adult and pediatric applications.

Abstract: Apparatus, systems and methods employing a contact lens having a pulse oximetry sensor to detect information indicative of a blood oxygen content and/or pulse rate of a wearer of the contact lens, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a pulse oximetry sensor located on or within the substrate that detects information associated with at least one of blood oxygen content or a pulse rate of a wearer of the contact lens. The pulse oximetry sensor comprises one or more light emitting diodes that illuminate a blood vessel of at least one of a region of an eye or an eyelid and a detector that receives light reflected from the blood vessel and generates the information.

Abstract: A sensor may be adapted to reduce motion artifacts by damping the effects of outside forces and sensor motion. A sensor is provided with a motion damping structure adapted to reduce the effect of motion of a sensor emitter and/or detector. Further, a method of damping outside forces and sensor motion is also provided.

Abstract: A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector.

Abstract: An intra-operative sensor device for detecting tissue or body parameters includes one or more light emitting sources and one or more photo-detectors. An optical isolator ring may be placed around either the one or more light emitting sources or around the one or more photo-detectors. The intra-operative sensor device may be a stand alone device or may be operatively coupled into a surgical instrument, such as a laparoscopic device.

Abstract: An optical sensor unit (10) for measuring a concentration of a gas is provided, comprising at least one sensing layer (122) adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer (121) adjacent to one side of the at least one sensing layer (122) and adapted to pass gas which concentration is to be measured through the gas-permeable layer (121) towards the sensing layer (122); a removable protective layer (150) covering at least the gas-permeable layer (121) and adapted to be removed before use of the optical sensor unit (10), wherein the optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (122), which optical response depends on the concentration of the gas.

Abstract: A physiological sensor has light sources arranged in one or more rows and one or more columns. Each light source is activated by addressing at least one row and at least one column. The light sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

Abstract: A flexible sensor pad includes a cavity to hold a sensor unit with an attached cable. According to one aspect of the present invention, a light-shielding layer is coupled to a bottom surface of the sensor pad, surrounds the sensor unit, and extends past two sides of the sensor pad. A transparent adhesive layer is coupled to the light-shielding layer and extends past two sides of the light-shielding layer. Another light shielding layer is coupled to a top surface of the sensor pad and covers the sensor unit. The cable divides the sensor pad into a first side and a second side which are mirror images of each other.

Abstract: A finger-placement sensor tape aligns and removably secures a finger to a sensor pad of a reusable finger-clip optical sensor so as to assure the finger is repeatably aligned between the sensors emitters and detectors and that the finger stays aligned during a test procedure. The sensor tape has a double-sided tape layer having a silicon-based adhesive on a finger side and an acrylic adhesive on a sensor-side. An aperture is defined in the tape layer so as to allow emitters disposed in a top sensor pad to emit light through the tape layer to detectors disposed in a bottom sensor pad. A finger-side release layer is removably disposed over the silicon-based adhesive. A sensor-side release layer is removably disposed over the acrylic adhesive.

Abstract: A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface.

Abstract: Apparatus, systems and methods employing a contact lens having a pulse oximetry sensor to detect information indicative of a blood oxygen content and/or pulse rate of a wearer of the contact lens, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a pulse oximetry sensor located on or within the substrate that detects information associated with at least one of blood oxygen content or a pulse rate of a wearer of the contact lens. The pulse oximetry sensor comprises one or more light emitting diodes that illuminate a blood vessel of at least one of a region of an eye or an eyelid and a detector that receives light reflected from the blood vessel and generates the information.

Abstract: The invention relates to a device for diagnosis and/or therapy of a selected portion of a body by optical reflectance or optical transmission. The device according to the invention has a laminar body (12) containing a tissue-facing surface (13). The laminar body (12) integrally forms a transmitter opening destined to accommodate a transmitter fiber terminal (24) and a receiver opening destined to accommodate a receiver fiber terminal (38a, 38b). Furthermore, it contains annular light shielding means for shielding said transmitter fiber terminal (24) and receiver fiber terminal (38a, 38b) from ambient light sources. Thereby, said annular transmitter and receiver light shielding means are formed as an annular transmitter light shielding bulge (46) and an annular receiver light shielding bulge (48a, 48b), respectively, which are firmly arranged with respect to said laminar body (12), whereby their free ends are protruding with respect to said tissue-facing surface (13) of said laminar body (12).

Abstract: Embodiments of the present disclosure relate generally to a sensor assembly. In various embodiments the sensor assembly includes a body having a first segment, a second segment, and a living hinge. The living hinge has a pivot axis and mechanically couples the first segment and the second segment. Further, the living hinge facilitates the first segment and the second segment to pivoting relative to one another about the pivot axis. Embodiments may also relate to a method of manufacturing a sensor frame. The method may include forming an integral sensor body having a first frame segment, a second frame segment, and a living hinge. The first frame segment and the second frame segment are configured to pivot relative to one another about a pivot axis of the living hinge. The method may also include coupling one or more biasing mechanisms to the first frame segment and the second frame segment. The biasing mechanism is configured to generate a moment about the pivot axis of the living hinge.