Infrared, Visible Light, Or Ultraviolet Radiation Directed On Or Through Body Or Constituent Released Therefrom Patents (Class 600/310)
  • Patent number: 11330361
    Abstract: A hearing aid includes a speaker driver, an optical source secured directly to the speaker driver, an optical detector secured directly to the speaker driver, a first light guide extending outwardly from the optical source and in optical communication with the optical source, and a second light guide extending outwardly from the optical detector and in optical communication with the optical detector. The first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector. The hearing aid may include at least one signal processor configured to process signals produced by the optical detector, and at least one of the following: an accelerometer, a humidity sensor, an altimeter, a temperature sensor.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: May 10, 2022
    Assignee: Valencell, Inc.
    Inventors: Wolfgang Wagner, Shawn Stephenson, Steven Matthew Just, Michael Edward Aumer, Jesse Berkley Tucker, Lawrence Christopher Eschbach, Steven Francis LeBoeuf
  • Patent number: 11324430
    Abstract: Example apparatuses, systems, and methods for detecting a muscle tissue ischemia event are provided. An example apparatus may include an electromyography (EMG) sensor applied to a patient to detect electrical activity in the muscle tissue. The apparatus may also include processing circuitry in communication with the EMG sensor and configured to receive EMG signals from the EMG sensor and detect characteristics within the EMG signals indicating oxygen depletion within the muscle tissue of the patient. The characteristics may include a signal power level of the EMG signals increasing by at least a threshold value at a select frequency or with respect to a select band of frequencies. The processing circuitry may be further configured to trigger an output, in response to detecting the characteristics, indicating that the oxygen depletion in the muscle tissue is indicative of an ischemia event.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: May 10, 2022
    Assignee: The Johns Hopkins University
    Inventor: Wayne I. Sternberger
  • Patent number: 11317821
    Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient includes an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue. The monitor also includes a perfusion status indicator indicating a perfusion status of the PPG signal, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP value based on a respiratory variation of the PPG signal. The FRP calculator applies a correction factor based on the perfusion status indicator.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: May 3, 2022
    Assignee: COVIDIEN LP
    Inventors: Paul Stanley Addison, Rui Wang, Scott McGonigle, James N. Watson
  • Patent number: 11319570
    Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a micro biosensor implanted subcutaneously to measure a physiological signal associated with an analyte. The micro biosensor includes a working electrode and a counter electrode, wherein the counter electrode includes silver and a silver halide having an initial amount. The method includes cyclic steps of: applying a measurement voltage to drive the working electrode to measure the physiological signal, where the silver halide is consumed by a specific amount; stopping applying the measurement voltage; and whenever the physiological parameter is obtained, applying a replenishment voltage to drive the counter electrode, thereby the silver halide of a replenishment amount being replenished to the counter electrode, wherein a guarding value of a sum of the replenishment amount and the initial amount subtracting the consumption amount is controlled within a range of the initial amount plus or minus a specific value.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: May 3, 2022
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11317873
    Abstract: A biological analysis device includes an average blood pressure calculation unit that calculates an average blood pressure index related to an average blood pressure of a biological body in accordance with a blood vessel diameter index related to a blood vessel diameter of the biological body and a blood flow index related to a blood flow of the biological body and calculated from an intensity spectrum related to a frequency of light reflected and received from an inside of the biological body through radiation of a laser beam.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: May 3, 2022
    Assignee: SEIKO EPSON CORPORATION
    Inventors: Kohei Yamada, Ayae Sawado, Akiko Yamada, Megumi Enari, Yuta Machida, Akira Ikeda, Masayasu Fukuoka, Akira Kitahara
  • Patent number: 11315742
    Abstract: A sticker-type electronic device which is freely detachably attachable to various bodies repeatedly is provided. The electronic device includes a main substrate which exhibits a surface adhesion property due to the properties of a material thereof and which provides an attachment/detachment surface to an article, and an electrode formed by being transferred from a temporary substrate to a surface that is opposite to the attachment/detachment surface of the main substrate to the article wherein the electrode is transferred directly to the main substrate using the adhesion property of the main substrate. The electronic device is freely detachably attachable to the surface of the article repeatedly using the surface adhesion property of the main substrate. The electronic device is formed directly on the surface of the substrate constituted by the material having the surface adhesion property, thereby providing a sticker-type electronic device which is freely repeatedly detachably attachable to various bodies.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: April 26, 2022
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Hana Yoon, Chung-yul Yoo, Sang-hyun Park, Jung-Joon Yoo, Younghyun Cho, Yeoung A Lee, Jiyoung Lee, Jaehyun Jeon
  • Patent number: 11313817
    Abstract: A variety of application can use nuclear magnetic resonance as an investigative tool. Nuclear magnetic resonance measurements can be conducted using a nuclear magnetic resonance microscope. An example nuclear magnetic resonance microscope can comprise a film embedded in a coverslip, where the film is doped with reactive centers that undergo stable fluorescence when illuminated by electromagnetic radiation having a wavelength within a range of wavelengths and a magnetic field generator to provide a magnetic field for nuclear magnetic resonance measurement of analytes when disposed proximal to the film. Microwave striplines on the coverslip can be arranged to generate microwave fields to irradiate the analytes for the nuclear magnetic resonance measurement. Control of the microwave signals on the microwave striplines can be used for dynamic nuclear polarization in the nuclear magnetic resonance measurement of analytes.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: April 26, 2022
    Assignee: UNM Rainforest Innovations
    Inventors: Victor Marcel Acosta, Andrejs Jarmola
  • Patent number: 11305037
    Abstract: A facemask includes integrated actuating modules having sensors and other mechanisms. The facemask has one or more sockets into which various modules may be inserted. The facemask itself or the modules may include air filters and check valves to regulate airflow along or through the various modules. The modules may detect various substances either in the ambient air or the air exhaled by the wearer. The facemask also includes modules for measuring pulmonary and/or cardiovascular exertion, lung capacity and other physiological metrics. Other modules may provide supplements, vitamins or other substances such as tobacco smoke or vapor from vaporizers to the wearer. The modules may include microcontrollers in wireless communication with software applications on electronic devices so that the facemask may also serve as a cellular phone.
    Type: Grant
    Filed: December 5, 2020
    Date of Patent: April 19, 2022
    Inventors: Patrick Damien O'Brien, Jez Noah Ali, Arthur Ali
  • Patent number: 11304615
    Abstract: Embodiments of the present application provide a biological feature detection apparatus. The detection apparatus includes: a light emitting unit and a light receiving unit. The light emitting unit is configured to emit light to a detection surface of a biological tissue, the light emitted by the light emitting unit being processed by the biological tissue and then transmitted to the light receiving unit, the light receiving unit is configured to receive the light and perform a photoelectric conversion to generate an original electrical signal for biological feature detection, and at least one of the adjustable relative position and relative angle is defined between the light emitting unit and the light receiving unit. As such, accurate monitoring of the biological feature is achieved.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: April 19, 2022
    Assignee: SHENZHEN GOODIX TECHNOLOGY CO., LTD.
    Inventor: Wangwang Yang
  • Patent number: 11307147
    Abstract: Techniques for colorimetric based test strip analysis and reader system are provided. In one aspect, a method of test strip analysis includes: illuminating a test strip wetted with a sample with select spectrums of light, wherein the test strip includes test pads that are configured to change color in the presence of an analyte in the sample; obtaining at least one digital image of the test strip; and analyzing color intensity from the at least one digital image against calibration curves to determine an analyte concentration in the sample with correction for one or more interference substances in the sample that affect the color intensity. A calibration method and a reader device are also provided.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: April 19, 2022
    Assignee: International Business Machines Corporation
    Inventors: Minhua Lu, Vince Siu, Russell Budd, Evan Colgan, John Knickerbocker
  • Patent number: 11278221
    Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ just the right amount of oxygen,? or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: March 22, 2022
    Assignee: REVEAL BIOSENSORS, INC.
    Inventor: Guy Meredith Hatch
  • Patent number: 11278230
    Abstract: An improved system for assessing cognitive function is described that uses tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, which, for example, can be encapsulated as a data structure. The data sets can include tracked specific response types, at different times and amplitudes, including, but not limited to, event related potential signal components. Brainwave features including, event related potentials, are tracked in relation to both pre-attentive brain responses and consciously controlled attention responses.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: March 22, 2022
    Assignee: MCMASTER UNIVERSITY
    Inventors: John Francis Connolly, Kyle Ingram Ruiter, Rober Boshra
  • Patent number: 11266320
    Abstract: An electronic device including optical sensing with a concentric architecture and methods for operation thereof is disclosed. The concentric architecture can include light detector(s) arranged in a concentric manner around light emitter(s). In some examples, at least one light emitter can be located in the center of the device, and each light detector can be located the same separation distance from the light emitter. Each light detector can be arranged such that the separation distance from the centrally located light emitter can be greater than the separation distance from another light emitter. Examples of the disclosure further include a selective transparent layer overlaying the light detector(s). The selective transparent layer can include section(s) transparent to a first wavelength range and non-transparent to a second wavelength ranges. In some examples, the selective transparent layer can further include section(s) transparent to the second wavelength range.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: March 8, 2022
    Assignee: Apple Inc.
    Inventors: Ueyn L. Block, Guocheng Shao, Itaru L. Hiromi, Mathieu Charbonneau-Lefort, Tobias J. Harrison-Noonan
  • Patent number: 11262241
    Abstract: A photo-thermal speckle spectroscopy device having an infrared laser, a visible laser, a foam, and a camera. The infrared and visible lasers are focused on the foam, which causes the visible laser to scatter. A camera records the speckle pattern, which shifts when the IR laser is turned on. The related method of photo-thermal speckle spectroscopy is also disclosed.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: March 1, 2022
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Robert Furstenberg, Chris Kendziora, R. Andrew McGill
  • Patent number: 11257213
    Abstract: In a computer implemented method of determining a boundary of a tumor region or other diseased tissue, hyper- or multispectral image data of a tissue sample including a tumor region or other diseased tissue is taken. The analysis includes a morphological analysis and a spectral analysis of the hyper- or multispectral image data resulting in a morphological tumor boundary and a spectral tumor boundary or a morphological diseased tissue boundary and a spectral diseased tissue boundary. These two boundaries are combined resulting in a combined tumor boundary or combined diseased tissue boundary, wherein an indication of reliability of the combined tumor boundary or combined diseased tissue boundary is given.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: February 22, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Bernardus Hendrikus Wilhelmus Hendriks, Hong Liu, Caifeng Shan
  • Patent number: 11246514
    Abstract: A non-invasive optical internal substance detector includes: a diode array including a plurality of light emitting diodes (LEDs) for emitting light toward a target where an internal substance is detected, and a plurality of photodiodes (PDs) for receiving light which is reflected from the target after being emitted from the plurality of light emitting diodes; and a controller for controlling the plurality of light emitting diodes to be turned on or off and for processing a signal obtained from the photodiodes. The plurality of light emitting diodes and the plurality of photodiodes each have a size of several micrometers to several tens of micrometers and are arranged at intervals of several micrometers to several tens of micrometers from each other.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: February 15, 2022
    Assignees: HYUNDAI MOTOR COMPANY, KIA MOTORS CORPORATION
    Inventors: Sang Hyeok Yang, Dong Gu Kim
  • Patent number: 11246486
    Abstract: An intra-body communication system for monitoring physiological changes in a patient is provided. The system can include a first device implanted into a patient's body; a second device spaced apart from the first device; and a receiver for detecting and/or decoding the signals to monitor physiological changes in the patient. The first device and second device are capable of engaging in a two-way communication through transmission of one or more signals through at least a portion of the patient's body between the first device and the second device. In one embodiment, the signal may be an optical signal.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: February 15, 2022
    Assignee: EFFERENT LABS, INC.
    Inventors: Spencer Z. Rosero, William K. Rader
  • Patent number: 11252498
    Abstract: An ear worn device includes an optical source, an optical detector, and a housing supporting the optical source and optical detector. The housing is configured to be positioned within an ear of a subject and includes a first light guide in optical communication with the optical source and a second light guide in optical communication with the optical detector. A distal end of the first light guide is configured to deliver light from the optical source into the ear, and a distal end of the second light guide is configured to collect light from the ear and deliver collected light to the optical detector. The first and second light guides define respective first and second axial directions that are outwardly diverging such that light rays directed into the ear via the first light guide cannot overlap with light rays collected by the second light guide.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: February 15, 2022
    Assignee: Valencell, Inc.
    Inventors: Wolfgang Wagner, Shawn Stephenson, Steven Matthew Just, Michael Edward Aumer, Jesse Berkley Tucker, Lawrence Christopher Eschbach, Steven Francis LeBoeuf
  • Patent number: 11252499
    Abstract: A monitoring device includes a band capable of at least partially encircling a portion of a body of a subject. An optical source and an optical detector are supported by the band. A first light guide is in optical communication with the optical source and a second light guide is in optical communication with the optical detector. A distal end of the first light guide is configured to deliver light from the optical source into the body, and a distal end of the second light guide is configured to collect light from the body and deliver collected light to the optical detector. The first and second light guides define respective first and second axial directions that diverge outwardly from the band such that light rays directed into the body via the first light guide cannot overlap with light rays collected by the second light guide.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: February 15, 2022
    Assignee: Valencell, Inc.
    Inventors: Wolfgang Wagner, Shawn Stephenson, Steven Matthew Just, Michael Edward Aumer, Jesse Berkley Tucker, Lawrence Christopher Eschbach, Steven Francis LeBoeuf
  • Patent number: 11241525
    Abstract: A stand-alone system for assessing wound exudates from the wound of a patient is described. The system contains functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may also compare detected physiological values to predetermined physiological values, in order to obtain a comparison result in real time. The system may include a processor (15) which provides an electronic signal based on the comparison result in which the electronic signal may corresponds to guidelines for treating the wound (3). The system described may be an accessory, which may be used on its own, or in conjunction with other wound treatment devices (9).
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: February 8, 2022
    Assignee: ConvaTec Technologies Inc.
    Inventor: Landy Aaron Toth
  • Patent number: 11234584
    Abstract: Medical imaging systems for use in conjunction with an endoscope are described. Generally, the medical imaging system includes an illumination source configured to generate illuminating photons. The illuminating photons are transmitted to one or more filters configured to filter a first plurality of illuminating photons and generate a first plurality of filtered photons comprising a first passband wavelength and a second plurality of filtered photons comprising a second passband wavelength. A sample is then illuminated with the first plurality of filtered photons and the second plurality of filtered photons to generate a first plurality of interacted photons and a second plurality of interacted photons. One or more detectors are configured to detect the first plurality of interacted photons and the second plurality of interacted photons and generate one or more image data sets.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: February 1, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Matthew P. Nelson
  • Patent number: 11235528
    Abstract: A carriageless print head assembly, for use in extrusion-based additive construction is disclosed. The carriageless print head features a cold end equipped with one or more timing belt attachment slots and bores for receiving bearings to achieve linear motion. The carriageless print head may be optionally equipped with some combination of an air conduit for cooling the top layer of the constructed product, a fluid channel for aiding in the regulation of the temperature of the print head cold end, and a thermal monitor for monitoring the temperature of the cold end of the print head. A computer-mediated method of monitoring the cold end of the print head to limit jams due to overheating is also disclosed.
    Type: Grant
    Filed: September 2, 2017
    Date of Patent: February 1, 2022
    Assignee: R3 Printing, Inc.
    Inventor: Paul Sieradzki
  • Patent number: 11234655
    Abstract: A perfusion trend indicator inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. Perfusion values are derived corresponding to the pulses. Time windows are defined corresponding to the perfusion values. Representative perfusion values are defined corresponding to the time windows. A perfusion trend is calculated according to differences between representative perfusion values of adjacent ones of the time windows.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: February 1, 2022
    Assignee: Masimo Corporation
    Inventor: Ammar Al-Ali
  • Patent number: 11229408
    Abstract: An optical based patient monitoring system employing an optical sensor and providing an indication of an optical change which does not correlate to a change in a physiological blood parameter and based on that indication, providing a care provider an indication of a condition of a patient. The optical based patient monitoring system providing the indication of the patient condition in relation to a patient using an IV setup.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: January 25, 2022
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, John Graybeal, Massi Joe E. Kiani, Michael Petterson, Chris Kilpatrick
  • Patent number: 11219428
    Abstract: A wearable electronic device configured to be worn by a user while performing an invasive procedure for enhancing visualization of desired anatomical structures is provided. The wearable electronic device includes: a housing; at least one imaging sensor associated with the housing; and a visual display integrally formed with or associated with the housing. The device is configured to acquire an image of an invasive access site of a patient with the at least one imaging sensor, process the image to determine a location of a desired anatomical structure, and display a virtual trace of the location to the user via the visual display.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: January 11, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Jonathan Karl Burkholz, Jeff O'Bryan, Siddarth K. Shevgoor, Yiping Ma
  • Patent number: 11207008
    Abstract: The present disclosure provides a system and method for analyzing a physiological parameter of a vital sign signal. The method may include acquiring a vital sign signal, storing data, computing and analyzing, processing, and outputting a result. The system may compute and analyze the physiological parameter of the vital sign signal, especially a blood oxygen saturation, via a plurality of algorithms, judge or process the computation result, and output the judgment result.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: December 28, 2021
    Assignee: VITA-COURSE TECHNOLOGIES (HAINAN) CO., LTD.
    Inventors: Ying Lu, Chuanmin Wei, Jiwei Zhao, Heng Peng, Ziming Deng, Zijian Huang, Zhiyong Wang
  • Patent number: 11191460
    Abstract: The present disclosure is directed to a method and device to determine the hemoglobin value of a mammal. The device includes a plurality of light emitting diodes, one or more sensors and a processor.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: December 7, 2021
    Assignee: Shani Biotechnologies LLC
    Inventor: Sanjay Gokhale
  • Patent number: 11185279
    Abstract: Techniques are described for detecting erythema caused by wearable devices. In various embodiments, a wearable device may include light source(s) to emit light at multiple wavelengths; light sensor(s) to receive light reflected from tissue of an individual that wears the wearable device; and logic configured to: operate the light source(s) to emit light at multiple wavelengths; receive a signal generated by the light sensor(s), wherein the signal is generated by the light sensor(s) in response to detection of light reflected from the tissue; analyze the signal to determine a first metric from a first wavelength of the light reflected from a first depth of the tissue and a second metric from a second wavelength of the light reflected from a second depth of the tissue; identify a correlation between the first and second metrics; and provide output indicative of tissue erythema based on the correlation.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: November 30, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Elise Claude Valentine Talgorn, Willem Verkruijsse, Lieven Adriaenssen
  • Patent number: 11172821
    Abstract: A system including a thermal sensor with an instrument placed in a volume. The thermal sensor may be useful in determining a temperature at a surface of the instrument and a distance away from the instrument. A therapy may be performed based on a sensed temperature with the thermal sensors.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: November 16, 2021
    Assignee: Medtronic Navigation, Inc.
    Inventors: Brad Jacobsen, Andrew Bzostek, Daniel Dunford, Benjamin D. Ewing, Amir Ghanei, Bryan Wilson, Janine Benavente
  • Patent number: 11160926
    Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: November 2, 2021
    Assignee: DexCom, Inc.
    Inventors: Jason Halac, John Charles Barry, Becky L. Clark, Chris W. Dring, John Michael Gray, Kris Elliot Higley, Jeff Jackson, David A. Keller, Ted Tang Lee, Jason Mitchell, Kenneth Pirondini, David Rego, Ryan Everett Schoonmaker, Peter C. Simpson, Craig Thomas Gadd, Kyle Thomas Stewart, John Stanley Hayes
  • Patent number: 11147438
    Abstract: An endoscope apparatus includes an illumination apparatus that applies first and second narrow-band light having different peak wavelengths to a subject, an imaging device that acquires image light from the subject with pixels to generate an acquisition image signal, and an image processing circuit. The image processing circuit includes a storage that has stored assumed subject types including information about a wavelength range of assumed subjects, and a subject type decision circuit that decides an assumed subject type for part of the pixels based on a first image signal about the first narrow-band light, a second image signal about the second narrow-band light, and the assumed subject types. The image processing circuit constructs a display image signal based on the acquisition image signal and decided assumed subject type.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: October 19, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Hiroyuki Kamee
  • Patent number: 11141087
    Abstract: A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source for exciting the target species and a probe beam with split frequency to measure the effect of excitation. The latter uses a heterodyne interferometer operating at a beat frequency ˜ KHz. to MHz. The photo-thermal excitation of target species leads to refractive index change. The RI change produces probe beam displacement and is measured using a 1) grating heterodyne interferometer, 2) grating deflection amplifier and 3) evanescent field heterodyne interferometer. The measured RI change can be related to specie concentration change in target volume. Furthermore, a sensing method for detecting HbA1c concentration and its change with thermal excitation is described in terms of phase shift of the OCT spectrum obtained with spectral domain optical coherence tomography (SD-OCT).
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: October 12, 2021
    Inventor: Arun Ananth Aiyer
  • Patent number: 11138734
    Abstract: A hyperspectral facial analysis system and method for personalized health scoring to assess the risk that a person has a disease. Embodiments capture images in multiple spectral bands, such as visible, infrared, and ultraviolet, and analyze these images to generate multiple health metrics, such as pallor, temperature, sweat, and chromophores. These metrics may be combined into an overall health score that may be used for screening. Image analysis may focus on the area under the eyes, where skin is thinnest. Images may be compared to a reference population to identify anomalous values, so that health scoring automatically adjusts for local conditions. Pallor may be calculated based on hue and saturation of visible light images. Temperature may be calculated based on infrared image intensity. Sweat may be calculated using cross-polarized images to identify specular highlights. Chromophores may be calculated by comparing frequency domain ultraviolet images to those of the reference population.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: October 5, 2021
    Assignee: VR Media Technology, Inc.
    Inventor: Charles Gregory Passmore
  • Patent number: 11112910
    Abstract: According to an embodiment, an electronic device, comprises a transparent member, an optical sensor disposed under the transparent member and including a light transmitter configured to emit light of a designated wavelength band and a light receiver configured to obtain light of the designated wavelength band emitted from the light transmitter and reflected by an external object adjacent to the transparent member, a first optical filter disposed between the transparent member and the optical sensor, having a first transmittance for light of the designated wavelength band, and configured to reflect light outside the designated wavelength band, and a second optical filter disposed between the transparent member and the first optical filter, having a second transmittance less than the first transmittance for light of the designated wavelength band, and configured to absorb at least a portion of the light reflected by the first optical filter.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: September 7, 2021
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jeonggyu Jo, Hyeongsoon Park, Bokyung Sim
  • Patent number: 11109771
    Abstract: A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes at least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: September 7, 2021
    Assignee: Vivonics, Inc.
    Inventor: Michele Pierro
  • Patent number: 11103279
    Abstract: System and methods are provided for adaptively and intraoperatively configuring an automated arm used during a medical procedure. The automated arm is configured to position and orient an end effector on the automated arm a desired distance and orientation from a target. The end effector may be an external video scope and the target may be a surgical port. The positions and orientations of the end effector and the target may be continuously updated. The position of the arm may be moved to new locations responsive to user commands. The automated arm may include a multi-joint arm attached to a weighted frame. The weighted frame may include a tower and a supporting beam.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: August 31, 2021
    Assignee: SYNAPTIVE MEDICAL INC.
    Inventors: Cameron Piron, Michael Wood, Gal Sela, Joshua Richmond, Murugathas Yuwaraj, Stephen McFadyen, Alex Panther, Nishanthan Shanmugaratnam, William Lau, Monroe M. Thomas, Wes Hodges, Simon Alexander, David Gallop
  • Patent number: 11096759
    Abstract: Operating a medical image recording device in the context of an image recording routine for a patient is provided. The image recording routine serves an image recording purpose. The image recording device is controlled based on operating parameters implemented by a controller of the image recording device. The operating parameters are identified completely automatically by an identification algorithm from input data describing at least the patient in the form of a patient model and/or the image recording purpose, and from a registration of the patient with a coordinates system of the image recording device. The operating parameters are used to control the image recording device. An examination region that is to be recorded for the patient and the image recording purpose are derived based on the registration.
    Type: Grant
    Filed: June 15, 2019
    Date of Patent: August 24, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: Martin Spahn, Philipp Bernhardt, Stefan Böhm, Boris Stowasser, Richard Obler, Stanislav Tashenov, Rudolf Leiblein, Andreas Berting, Markus Lendl, Oliver Baruth
  • Patent number: 11089983
    Abstract: Embodiments herein relate to implantable multimode analyte sensors and medical devices including the same. In an embodiment, an implantable medical device is included having an optical excitation assembly, an optical detection assembly and a multimode sensing element. The multimode sensing element can include a colorimetric response element specific for a first chemical analyte and a photoluminescent response element specific for a second chemical analyte. Other embodiments are also included herein.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: August 17, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yingbo Li, Michael J. Kane, Keith R. Maile
  • Patent number: 11076780
    Abstract: A new wideband acoustic immittance measurement apparatus is provided for determination of wideband acoustic immittance in the ear of the human, the apparatus comprising an ear probe for insertion in an ear canal of the human and having an acoustic output port for emission of sound into the ear canal of the human, and an acoustic input port for reception of sound from the ear canal of the human, and a loudspeaker that is arranged for acoustical connection with the acoustic output port of the ear probe for emission of the sound, and a microphone that is arranged for acoustical connection with the acoustic input port of the ear probe for generation of an audio signal as a function of sound received at the acoustic input port, and a processor that is adapted for controlling the loudspeaker to emit sound spanning a frequency range, and receiving the audio signal of the microphone, determining a complex acoustic admittance Y(f)=G(f)+jB(f) as a function of frequency f based on the emitted sound and the received audi
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: August 3, 2021
    Assignee: Natus Medical Incorporated
    Inventors: Camilla MacGregor Magnussen, Ask Bojesen
  • Patent number: 11070550
    Abstract: A device having a fingerprint reader and a first heart rate monitor which are co-located such that a person's heart rate is obtained at the same time as this fingerprint. The device is integral to yet another heart rate monitor for monitoring the performance of the person in exercise. The readings of the other heart rate monitor correlates to the readings of the first heart rate monitor if the person whose fingerprint is read is the same person wearing the second heart rate monitor, in which case the fingerprint is deemed acceptable for identifying the person. Other biometric identification besides fingerprint can be used such as iris recognition.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: July 20, 2021
    Assignee: WELL BEING DIGITAL LIMITED
    Inventors: Juergen Harald Rahmel, Wong Ming Yip Wallace
  • Patent number: 11064947
    Abstract: An apparatus for measuring biometric information is provided. The apparatus may include: a main body configured to be worn on an object to be examined. The main body may include a contact pressure sensor configured to measure a contact pressure of the object while a hand shape is changing; a pulse wave sensor configured to measure a pulse wave signal of the object; and a processor configured to measure biometric information on the basis of the measured contact pressure and pulse wave signal.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: July 20, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jae Min Kang, Yong Joo Kwon, Seung Woo Noh, Sang Yun Park
  • Patent number: 11064908
    Abstract: An apparatus for obtaining an antioxidant index may include an image acquirer configured to acquire an image by capturing a correction reference object and a skin of a user and a processor configured to determine a first degree of yellowness of the correction reference object and a second degree of yellowness of the skin based on the image, and determine an antioxidant index of the user based on the first degree of yellowness and the second degree of yellowness.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: July 20, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jin Young Park, Sung Mo Ahn, Min Jung Son
  • Patent number: 11051765
    Abstract: A health status detecting system includes a first acquisition device configured to collect a plurality of images of a finger of a user; a second acquisition device configured to obtain an electrocardiogram of the user; and a processor configured to process the plurality of images to obtain a pulse wave of the user and configured to obtain a blood pressure of the user based on the pulse wave and the electrocardiogram of the user.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: July 6, 2021
    Assignee: SHANGHAI OXI TECHNOLOGY CO., LTD
    Inventors: Ketao Lu, Hong Zhu, Weiping Lin
  • Patent number: 11057991
    Abstract: Described herein are flexible and stretchable LED arrays and methods utilizing flexible and stretchable LED arrays. Assembly of flexible LED arrays alongside flexible plasmonic crystals is useful for construction of fluid monitors, permitting sensitive detection of fluid refractive index and composition. Co-integration of flexible LED arrays with flexible photodetector arrays is useful for construction of flexible proximity sensors. Application of stretchable LED arrays onto flexible threads as light emitting sutures provides novel means for performing radiation therapy on wounds.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: July 6, 2021
    Assignees: The Board of Trustees of the University of Illinois, Trustees of Tufts College
    Inventors: John A. Rogers, Rak-Hwan Kim, Dae-Hyeong Kim, David L. Kaplan, Fiorenzo G. Omenetto
  • Patent number: 11045096
    Abstract: A finger blood monitor apparatus for easily measuring blood pressure, pulse, and oxygen saturation includes a cylindrical housing defining a housing cavity. A front end has a finger aperture extending through to the housing cavity and a battery compartment is coupled within the housing cavity adjacent a battery aperture. A control panel is coupled within the housing cavity and has a plurality of control buttons extending through the sidewall. A CPU is coupled within the housing cavity and is in operational communication with the control panel and the battery compartment. A plurality of sensors is coupled within the housing cavity to measure a user's pulse, blood pressure, and peripheral oxygen saturation and display the readings on a plurality of display screens coupled within the sidewall.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: June 29, 2021
    Inventor: Francis Ndeithi
  • Patent number: 11045122
    Abstract: A near infrared spectrometer and method for wavelength and path length correction are disclosed. The spectrometer includes a number of photodiodes that transmit broadband near infrared measurement light into the tissue and at least one broadband detector which measures the light signal transmitted through the tissue. A processor estimates chromophore concentrations through a comparison of measured light attenuation and modeled light attenuation. The light attenuation model utilizes a light path length distribution derived from a Monte Carlo model and accounts for the spectral shape of the light source as a function of temperature.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: June 29, 2021
    Assignee: Fortiori Design LLC
    Inventors: Bryan J. Scheele, Nicholas H. Finstrom, Roger W. Schmitz
  • Patent number: 11026633
    Abstract: A motion artifact detecting method using wavelet transform which is capable of removing the problem caused by a radio noise and a motion artifact generated during the measurement of a PPG signal which is one of bio-signals, the method including: measuring a PPG signal; generating a signal obtained by removing a radio noise from the measured PPG signal; setting a reference signal from the signal from which the radio noise is removed; selecting a base signal based on the set reference signal; performing wavelet transform using the base signal; and detecting and removing a motion artifact using the wavelet-transformed value.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: June 8, 2021
    Assignee: UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
    Inventors: Sungoh Kwon, Da Hee Ban
  • Patent number: 11020014
    Abstract: A photoplethysmogram device is provided comprising a light source configured to emit light to illuminate skin, a photo-detector configured to receive the light illuminating the skin and generate an electrical output as a function of an intensity of the received light, a skin temperature regulator configured to heat and/or cool a temperature of the skin adjacent to the photo-detector and light source to increase the signal-to-noise ratio (SNR) of the electrical output from the photo-detector, and a processor configured to generate, based on the electrical output, an output signal indicative of blood properties, including physiological parameters such as blood pressure, heart rate, stroke volume, cardiac output, total peripheral resistance, blood vessel elasticity, and arterial oxygen saturation.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: June 1, 2021
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Sidhant Gupta, Jonathan Bernard Lester, Jeremiah Wander, Jessica De Souza
  • Patent number: 11000214
    Abstract: A physical condition management device and a method thereof capable of performing early detection of metabolic disease, nutritional guidance, and a physical condition management diagnosis. The physical condition management device includes: an irradiation unit configured to radiate light at a predetermined light intensity toward an inside of a living body from outside of the living body; a light intensity detection unit configured to detect light intensity emitted from the living body; a scattering coefficient calculation unit configured to calculate a scattering coefficient of light inside the living body on the basis of the detected light intensity; a particle diameter calculation unit configured to calculate a variation of an average particle diameter of a lipid in blood on the basis of a variation of the scattering coefficient; and a physical condition determination unit configured to determine a physical condition from a temporal change in the variation of the average particle diameter.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: May 11, 2021
    Assignee: MEDICAL PHOTONICS CO., LTD.
    Inventor: Kazuya Iinaga
  • Patent number: RE49024
    Abstract: A fundus observation apparatus that is capable of assisting an examiner in judging the presence or absence of abnormality in an examinee's eye based on a fundus tomographic image. The fundus observation apparatus includes an optical coherence tomography device that has an optical scanner for setting an image pickup position on a fundus of an examinee's eye, and is arranged to obtain a tomographic image of the fundus, and an information display unit that is arranged to display on a monitor the tomographic image obtained by the optical coherence tomography device and assisting information for assisting an examiner in performing judgment on the tomographic image, and the information display unit is arranged to change the assisting information based on image pickup information on the tomographic image.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: April 12, 2022
    Assignee: NIDEK CO., LTD.
    Inventors: Naoki Isogai, Toshio Murata