Abstract: A band device according to an aspect of the present disclosure includes a sensor unit, and a band unit that is linked to the sensor unit and forms a hollow part together with the sensor unit. The band unit includes an end piece section to which a watch head section is attached, and an engaging section that makes detachable engagement in a state where the band unit is wrapped around a wrist.

Abstract: To objectively grasp a stress state of a user and to prevent a mental disorder of the user, biogas information is acquired via a network that represents a concentration of dimethyl adipate of a user acquired by a sensor that detects dimethyl adipate discharged from a skin surface of the user. From a memory, information representing an upper limit of a normal range of the concentration of dimethyl adipate per unit period of time is obtained. A stress time period is determined during which a concentration of the dimethyl adipate of the user is more than the upper limit of the normal range, based on the acquired biological gas information; and time period information indicating the determined stress time period is outputted to an information terminal of the user, to display the stress time period indicated by the time period information on a display of the information terminal.

Abstract: Stereo visualization systems with optical filters for selective detection of color, multispectral, fluorescence, and laser mapping image data. A system includes a stereo camera comprising a first image sensor and a second image sensor, with a first optical filter that prevents the first image sensor from accumulating near infrared electromagnetic radiation. The system includes an emitter comprising a plurality of sources of electromagnetic radiation. The first image sensor detects visible electromagnetic radiation and reads out a visible data frame in response to the emitter cycling on a visible source, and the second image sensor detects near infrared electromagnetic radiation and reads out a near infrared data frame in response to the emitter cycling on a near infrared source.

Abstract: The present disclosure provides a wearable component. The wearable component includes a first carrier and a first electronic component at least partially embedded within the first carrier. The first carrier and the first electronic component define a space configured for audio transmission. An ear tip and a method of manufacturing a wearable component are also provided.

Abstract: One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.

Abstract: A method of verifying display of primary visual information on a screen of an electronic visual display device in which primary visual information is displayed on the screen of the display device. Visual verification information is simultaneously displayed at a verification location of the screen. The verification location is monitored using an optical detector to determine if the visual verification information is displayed. Display of the primary visual information is verified if it is determined that the verification information has been displayed.

Abstract: This document describes techniques and devices for blood-solute calculation with a mobile device using non-invasive spectroscopy. A mobile device (502) includes a light source (504) that emits light toward an interferometer (508) that uses mirrors to separate and recombine the light. The interferometer directs the recombined light toward a person. Light reflected from, or transmitted through, the person is received through a reception port (506) to a photodetector (510) that outputs photodetector data that corresponds to a measured light intensity of the reflected and transmitted light as a function of a path length of the light or a mirror position of the interferometer. Based on the photodetector data, an interferogram is generated. Applying a technique such as a Fourier transform to the interferogram, a spectrum data set of the reflected and transmitted light is generated. Based on the spectrum data set, a concentration of solutes in the person's blood is calculated.

Abstract: A biological component measurement apparatus includes an optical medium, an excitation light source, a probe light source, and a light position detector. The optical medium includes a sample placement surface. The excitation light source emits excitation light toward a sample placed on the sample placement surface. The probe light source emits probe light that travels through the optical medium. The light position detector detects the position of the probe light outgoing from the optical medium. The optical medium is formed from chalcogenide glass.

Abstract: A device may obtain absorption spectra data associated with tissue of a subject. The device may determine, based on the absorption spectra data, an estimate of a water content associated with the tissue. The device may determine, based on the estimate of the water content, an estimate of a hydration level of the subject. The device may perform one or more actions based on the estimate of the hydration level of the subject.

Abstract: An instrumented mold formed by an assembly of strata includes, within the assembly of strata, a measurement structure provided with at least one pressure sensor and/or at least one temperature sensor or any other sensor capable of measuring a physical quantity, the structure typically being in the form of a flexible support housed between two strata.

Abstract: Apparatus and methods are described for ultrasound guided optoacoustic monitoring to provide diagnostic information for many clinical applications blood oxygenation in blood vessels and in tissues including for early diagnosis and management of circulatory shock (including that induced by hemorrhage). In certain embodiments provided herein, methods and apparatus for optoacoustics for measurement of blood oxygenation in the innominate vein are provided.

Abstract: An oximetry probe and an operating method thereof, and an oximetry sensor. The oximetry probe includes an oximetry sensor which includes a detection end and an output end, and an adapter. The detection end includes a photodetector and multiple light-emitting elements connected in series. The output end has multiple output ports. Adjacent output ports are electrically connected to two sides of the corresponding light-emitting element. The adapter has a first adapter end and a second adapter end between which multiple wires are provided. The first adapter end is electrically connected with an input end of the monitor. When the second adapter end is connected to the output end, the wires are electrically connected with the output ports to form closed circuit to enable the light-emitting element to emit light which is received by the photodetector to generate a signal involving blood oxygen saturation to be displayed on the monitor.

Abstract: A biosensor system has a capsule with a housing configured for ingesting in a mammal GI tract, being cylindrical with domed ends. The housing forms an external space akin to a “cut-out” shape with two opposing transparent walls facing each other in the longitudinal direction and a base wall facing radially. An LED emitter emits at a number of wavelengths in time sequence, and radiation is detected by a photo-detector via the wall which forms a concave lens. An antenna is for wireless transmission of data to an external device and is in the form of conical spiral in an overall conical shape, located for optimum space efficiency in a domed end. A battery compartment is at the opposed end of the housing, separated from the antenna by the external space.

Abstract: An apparatus for analyzing a biological material component may include an impedance sensor comprising a first electrode having a first contact surface that contacts an analysis target, and a second electrode having a second contact surface that contacts the analysis target and that faces the first contact surface. The apparatus may include an impedance measurement assembly configured to measure impedance of the analysis target using the first electrode and the second electrode. The apparatus may include a processor configured to model the measured impedance as an equivalent circuit, and analyze a biological material component based on a modeling result.

Abstract: A method and system are provided for measuring post-translational modification of proteins in a subject. The method comprises recording of infrared radiation within a predetermined wavenumber range and attenuated by an integument of the subject, such that the integument is still attached to the subject. The method further comprises the step of comparing the attenuation of infrared radiation to a predetermined value for deriving information regarding post-translational modification of proteins in the integument.

Abstract: This optical measurement system 100 is provided with a plurality of optical measurement units 1 and a control device 2 that controls the optical measurement unit. The control device includes a communication unit 24 that obtains specific state information 30 on whether or not the optical measurement unit is in a measurable state by communication for each of a plurality of optical measurement units, a display unit 25 that collectively displays the obtained state information for each of the plurality of optical measurement units, and a control unit 21 that controls a plurality of optical measurement units so that a simultaneous measurement is performed.

Abstract: Methods and systems for determining extracellular concentration data of an analyte are disclosed. A method for determining extracellular concentration data of an analyte includes receiving sensor data from one or more arrays of functionalized plasmonic nanostructures on a localized surface plasmon resonance imaging chip in contact with a fluid containing at least one living cell for a plurality of times, determining intensity data for the one or more arrays, determining fractional occupancy based on the intensity data, and determining extracellular concentration data based on the fractional occupancy data. A system for determining extracellular concentration data of an analyte includes a LSPRi chip, a sensor component, an intensity component, a fractional occupancy component, a concentration component, and a processor to implement the components.

Abstract: In some aspects, a head mounted device may include an eye portion configured to face an eye of a user wearing the head mounted device, where the eye portion includes a display. The head mounted device may include at least one light emitter configured to emit light for illuminating at least a portion of a nose of the user. The head mounted device may include at least one image sensor configured to capture an image of at least a portion of the nose of the user for use in determining a shift or a rotation of the head mounted device relative to the user. Numerous other aspects are provided.

Abstract: Various sensor tapes can improve securing of a non-invasive optical sensor to a surface of a medium for taking noninvasive measurement of characteristics of the medium. The sensor tape can taper from a wide end to a narrow end. The sensor tape can transition from a wide portion to a narrow portion in a step-like change or slope. The sensor tape can have staggered portions. The various tapes can be used with an L-shaped sensor. The various tapes can increase contact surface between the surface of the medium and an adhesive side of the tape so as to reduce motion-induced noise.

Abstract: A wideband acoustic immittance measurement apparatus including an ear probe having an acoustic output port for emitting sound into an ear canal and an acoustic input port for receiving sound from the ear canal, a loudspeaker that is acoustically connected with the acoustic output port, a microphone acoustically connected with the acoustic input port for generating an audio signal as a function of sound received at the acoustic input port, and a processor for controlling the loudspeaker to emit sound spanning a frequency range and receiving the audio signal of the microphone, determining a complex acoustic admittance Y(f)=G(f)+jB(f) as a function of frequency f based on the emitted sound and the received audio signal, and identifying at least one middle ear resonance based on both the real and imaginary part of the determined acoustic admittance as a function of frequency f.

Abstract: The disclosure relates to converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT), and may be applied to intelligent services based on the 5G communication technology and IoT-related technology. To do so, a method and apparatus are provided for transmitting groupcast/broadcast/multicast data and control information in the downlink and uplink. The method and apparatus include features for transmitting to a user equipment (UE), configuration information for multicast and broadcast services (MBS), encoding a first bit sequence for the MBS based on a channel coding, identifying a transport block size (TBS) for limited buffer rate matching (LBRM) based on the configuration information, performing the LBRM to the encoded first bit sequence based on the identified TBS, and transmitting to the UE, a second bit sequence identified based on the LBRM.

Abstract: The present disclosure concerns a sensor assembly for measuring displacement of a contact surface at least along a central axis of the assembly caused by pressure applied on the surface by the skin of a user during measurement of at least one biological parameter of the user.

Abstract: A method and system for measuring personal health, the method comprising detecting a photoplethysmograph (PPG) wave, the PPG wave generated based on a combination of infra-red and red lights, transmitting the PPG wave to a server, the server processing the PPG wave to infer biometric statistics based on machine learned correlations generated from a training set of PPG waves and biometric data, receiving the biometric statistics from the server, and generating display data based on the biometric statistics.

Abstract: An apparatus for estimating bio-information includes a sensor configured to measure a bio-signal from an object, and a processor configured to obtain a feature based on the measured bio-signal, obtain a bio-information variation based on the obtained feature, obtain an adjustment coefficient based on the obtained bio-information variation, and estimate the bio-information by applying the obtained adjustment coefficient to the obtained bio-information variation.

Abstract: Methods and apparatus for measuring perfusion using transmission laser speckle imaging are provided. The apparatus comprises a coherent light source and a detector configured to measure transmitted light associated with an unfocused image at one or more locations. The coherent light source and detector are positioned in a transmission geometry. The apparatus further comprises means for securing the coherent light source and the detector to the tissue sample in a fixed transmission geometry relative to the tissue sample. The apparatus may further comprise at least one processor to receive information from the detector and process detected variations in transmitted light intensity to determine a single metric of perfusion. The method may comprise the steps transilluminating a tissue sample with coherent light, recording spatial and/or temporal variations in the transmitted light signal, determining speckle contrast value(s), and computing a metric of perfusion.

Abstract: One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.

Abstract: A method for determining sub-diffuse scattering parameters of a material includes illuminating the material with structured light and imaging remission by the material of the structured light. The method further includes determining, from captured remission images, sub-diffuse scattering parameters of the material. A structured-light imaging system for determining sub-diffuse scattering parameters of a material includes a structured-light illuminator, for illuminating the material with structured light of periodic spatial structure, and a camera for capturing images of the remission of the structured light by the material. The structured-light imaging system further includes an analysis module for processing the images to quantitatively determine the sub-diffuse scattering parameters. A software product includes machine-readable instructions for analyzing images of remission of structured light by a material to determine sub-diffuse scattering parameters of the material.

Abstract: Disclosed are apparatuses, systems, and techniques to render images depicting light interacting with media that have volume attenuation, using optimized spectral rendering that emulates rendering of the media in tristimulus color rendering schemes.

Abstract: This invention is directed to non-invasive devices and methods to detect electrochemically active molecules in a fluid sample of a subject.

Abstract: A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material.

Abstract: Methods and systems for treating a disease include navigating a symptom-centric decision tree which accounts for probabilities for symptoms and diseases and emergency values for the symptoms and diseases, based on information provided by a user, to determine a disease. A treatment is provided to the user based on the determined disease.

Abstract: A three-dimensional Raman image mapping measuring device for a flowable sample according to an embodiment of the present disclosure is designed to be capable of measuring a flowable sample during mapping measurement of a three-dimensional image that is a region of a confocal Raman by using a micro Raman spectrometer and a three-axis sample stage (Piezo stage). The three-dimensional Raman image mapping measuring device for a flowable sample includes at least one piezo element; an element holder equipped with the piezo element and having an opening, a sample stage for supporting the element holder equipped with the piezo element, an objective lens mounted in the opening in the element holder, a sample holder for controlling vertical movement of the flowable sample disposed under the lower portion of the sample stage, and a transparent window disposed between the sample stage and the sample holder.

Abstract: The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.

Abstract: An optoelectronic sensor module and a method for producing an optoelectronic sensor module are disclosed. In an embodiment an optoelectronic sensor module includes a first semiconductor transmitter chip configured to emit radiation of a first wavelength, a second semiconductor transmitter chip configured to emit radiation of a second wavelength different from the first wavelength, a semiconductor detector chip configured to detect the radiation of the first and second wavelengths, and a first potting body being opaque to the radiation of the first and the second wavelength, wherein the first potting body directly covers side surfaces of the chips and mechanically connects the chips located in a common plane to one another, wherein a distance between the chips is less than or equal to twice an average diagonal length of the chips, and wherein the sensor module is adapted to rest against a body part to be examined.

Abstract: A photoacoustic apparatus includes a light source configured to generate a plurality of pulsed lights in different wavelengths, an irradiation optical system configured to irradiate an object with the pulsed light from the light source and configured to irradiate the object in different irradiation positions along a rotational trajectory during a rotational scanning period in a corresponding wavelength, and a probe configured to receive photoacoustic wave from the object in response to each pulsed light irradiation in the different irradiation positions and to convert the received photoacoustic wave into an electric signal. The irradiation optical system is moved to irradiate the object with a first wavelength in a plurality of times during a first rotational scanning period and irradiate the object with a second wavelength in a plurality of times during a second rotational scanning period after the first rotational scanning period.

Abstract: An apparatus and method for detecting a bio-signal feature are provided. The apparatus according to one aspect may include: a bio-signal acquirer configured to acquire a bio-signal; and a processor configured to generate an envelope signal of the bio-signal, and detect at least one feature of the bio-signal based on a difference between the envelope signal and the bio-signal.

Abstract: A neural sensing system includes an interrogator that includes an optical head. The optical head is configured to transmit a light signal. The neural sensing system also includes a microprobe configured to contact tissue. The microprobe includes a transducer configured to receive the light signal and modulate the light signal with neural signal information sensed from the tissue. The microprobe also includes a retroreflector configured to reflect the modulated light signal back to the optical head of the interrogator.

Abstract: The present invention relates to a parathyroid sensing system, and includes: a modulator for generating a modulation signal having a predetermined frequency; a lock-in amplifier and a light source which receive information on the modulation signal; an excitation filter for transmitting, among light emitted from the light source, only excitation light that excites parathyroid glands; an emission filter connected to a probe and selectively transmitting only fluorescence emitted from the parathyroid glands; a near-infrared sensor for sensing the autofluorescence that has passed through the emission filter, and converting the sensed autofluorescence into an electric signal; and a speaker for generating an alarm through the electric signal. Through the present invention, the locations of the parathyroid glands may be precisely identified even when lights are turned on in an operating room, and convenience may be provided by alerting a surgeon by means of an alarm when the parathyroid glands are detected.

Abstract: A wearable device for healthcare and a method thereof, wherein the device is worn on a finger for measuring the health data of the user, including but not limited to, the heart rate, blood oxygen saturation, etc. The wearing size of the device is adjustable for different sizes of fingers. In one embodiment, the device includes a main body at least partially worn on a digit of a user; at least one physiological sensor attached to the main body for detecting physiological information; and at least two branches coupled to the main body for holding the digit while reducing the movement of the device. At least a part of at least one branch is changeable such that the wearing size of the device is adjustable for different sizes of digits. In another embodiment, at least a part of at least one branch is movable such that the wearing size of the device is adjustable for different sizes of digits.

Abstract: The present disclosure relates to optical methods and devices based on pulsate behavior of blood and optical absorption spectroscopy to measure the level of water and/or other substances or compounds, such as an alcohol or lipid, in the blood and the tissues surrounding blood vessels and arteries.

Abstract: An antioxidant sensor includes a pressure sensor configured to obtain a contact pressure between an object and an optical sensor; the optical sensor configured to, based on the obtained contact pressure exceeding a set threshold pressure, emit a first light of a first wavelength to the object, and receive the first light reflected or scattered from the object; and a processor configured to determine a contact portion of the object in contact with the optical sensor, set a threshold pressure, among different threshold pressures, according to the determined contact portion, and determine an antioxidant value based on the received first light.

Abstract: A device includes source and detector sensors. In a specific implementation, the device has two near detectors, two far detectors, and two sources. The two near detectors are arranged closer to the two sources than the two far detectors. A light-diffusing layer covers the two near detectors. The device may be part of a medical device that is used to monitor or measure oxygen saturation levels in a tissue. In a specific implementation, light is transmitted into the tissue and received by the detectors. An attenuation coefficient is first calculated for a shallow layer of tissue. The attenuation coefficient is then used to calculate an attenuation coefficient for a deep layer of tissue.

Abstract: Techniques for measuring metabolic tissue state and oxygenation in human or animal models, through optical techniques capable of simultaneous measurement at single region of interest. Simultaneously measuring CCO, oxygenated hemoglobin (HbO), and deoxygenated (HbR) hemoglobin is performed and metabolic activity of the tissue is determined. The methods employ a super-continuum light source and a probe to deliver light to the individual, and reflected light from the individual is analyzed to determine the metabolic function of the individual.

Abstract: A system for simultaneously detecting audio-characteristics within a body over multiple body surface locations comprising a coherent light source directing at least one coherent light beam toward the body surface locations, an imager acquiring a plurality of defocused images, each is of reflections of the coherent light beam from the body surface locations. Each image includes at least one speckle pattern, each corresponding to a respective coherent light beam and further associated with a time-tag. A processor, coupled with the imager, determines in-image displacements over time of each of a plurality of regional speckle patterns according to said acquired images. Each one of the regional speckle patterns is at least a portion of a respective speckle pattern. Each regional speckle pattern is associated with a respective different body surface location. The processor determines the audio-characteristics according to the in-image displacements over time of the regional speckle patterns.

Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a fixing indentation containing the sensor, a filler disposed in the fixing indentation to retain the sensor in the holder, and a blocking element disposed between the implantation hole and the fixing indentation to hold the sensor in the holder and restrict the filler in the fixing indentation.

Abstract: An electronic device may include a housing and a PhotoPlethysmoGram (PPG) sensor disposed inside the housing. The PPG sensor may include a first Light Emitting Diode (LED) configured to generate light in a first wavelength band, a second LED configured to generate light in a second wavelength band, a third LED configured to generate light in a third wavelength band, a fourth LED configured to generate light in a fourth wavelength band, and a light receiving module including at least one photo diode. The electronic device may include a processor operatively coupled with the PPG sensor and a memory operatively coupled with the processor. The memory may include instructions that, when executed, cause the processor to measure optical densities of the light generated by the first LED to the fourth LED, and calculate a blood glucose value based at least in part on the measured optical densities.

Abstract: The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue layer, such as the dermis, of a person for analysis in a noninvasive analyte property determination systemy, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.

Abstract: An integrated circuit comprises: at least one photonic layer that includes one or more optical waveguides; a first optical coupler that couples at least a first optical mode outside of the photonic layer to a first waveguide in the photonic layer; a photonic device that includes one or more ports in the photonic layer; a first multi-port optical coupler that includes three or more ports in the photonic layer, including a first port optically coupled to the first optical coupler, a second port optically coupled to a first port of the photonic device, and a third port optically coupled to a first optical reflector configured to send substantially all optical power emitted from the third port of the first multi-port optical coupler back to the third port of the first multi-port optical coupler.

Abstract: The invention relates to the field of laser technology and can be used for more efficient optical pumping of laser media in laser generators and amplifiers. The invention can be used for the efficient optical pumping of practically all types of lasers, provided that the absorption profile of the pumped medium is sufficiently broadband. The invention discloses a method and device for combining at least two laser beams of different wavelengths, the polarization states of which are substantially orthogonal, into an exit beam by using a polarizing beamsplitter which spatially combines two beams in mutually orthogonal polarization states, and then changing the polarization state of one of the beams relative to the other using a spectrally selective polarization filter such that the polarization state of the exit beam becomes substantially identical for all of the wavelengths of the exit beam, thus permitting the subsequent combining thereof with another beam.

Abstract: An apparatus comprising an acoustic transducer arrangement configured to transmit at least one acoustic signal and configured to detect a reflection of said at least one acoustic signal, and a controller configured to determine a time-of-flight of the at least one acoustic signal, the controller further configured to determine at least a first value indicative of temperature based on said time-of-flight of the at least one acoustic signal and calibration information indicative of a relationship between time-of-flight and temperature in a space the apparatus is located.