Abstract: The disclosure relates to converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT), and may be applied to intelligent services based on the 5G communication technology and IoT-related technology. To do so, a method and apparatus are provided for transmitting groupcast/broadcast/multicast data and control information in the downlink and uplink. The method and apparatus include features for transmitting to a user equipment (UE), configuration information for multicast and broadcast services (MBS), encoding a first bit sequence for the MBS based on a channel coding, identifying a transport block size (TBS) for limited buffer rate matching (LBRM) based on the configuration information, performing the LBRM to the encoded first bit sequence based on the identified TBS, and transmitting to the UE, a second bit sequence identified based on the LBRM.

Abstract: The present disclosure concerns a sensor assembly for measuring displacement of a contact surface at least along a central axis of the assembly caused by pressure applied on the surface by the skin of a user during measurement of at least one biological parameter of the user.

Abstract: A method and system for measuring personal health, the method comprising detecting a photoplethysmograph (PPG) wave, the PPG wave generated based on a combination of infra-red and red lights, transmitting the PPG wave to a server, the server processing the PPG wave to infer biometric statistics based on machine learned correlations generated from a training set of PPG waves and biometric data, receiving the biometric statistics from the server, and generating display data based on the biometric statistics.

Abstract: An apparatus for estimating bio-information includes a sensor configured to measure a bio-signal from an object, and a processor configured to obtain a feature based on the measured bio-signal, obtain a bio-information variation based on the obtained feature, obtain an adjustment coefficient based on the obtained bio-information variation, and estimate the bio-information by applying the obtained adjustment coefficient to the obtained bio-information variation.

Abstract: Methods and apparatus for measuring perfusion using transmission laser speckle imaging are provided. The apparatus comprises a coherent light source and a detector configured to measure transmitted light associated with an unfocused image at one or more locations. The coherent light source and detector are positioned in a transmission geometry. The apparatus further comprises means for securing the coherent light source and the detector to the tissue sample in a fixed transmission geometry relative to the tissue sample. The apparatus may further comprise at least one processor to receive information from the detector and process detected variations in transmitted light intensity to determine a single metric of perfusion. The method may comprise the steps transilluminating a tissue sample with coherent light, recording spatial and/or temporal variations in the transmitted light signal, determining speckle contrast value(s), and computing a metric of perfusion.

Abstract: One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.

Abstract: A method for determining sub-diffuse scattering parameters of a material includes illuminating the material with structured light and imaging remission by the material of the structured light. The method further includes determining, from captured remission images, sub-diffuse scattering parameters of the material. A structured-light imaging system for determining sub-diffuse scattering parameters of a material includes a structured-light illuminator, for illuminating the material with structured light of periodic spatial structure, and a camera for capturing images of the remission of the structured light by the material. The structured-light imaging system further includes an analysis module for processing the images to quantitatively determine the sub-diffuse scattering parameters. A software product includes machine-readable instructions for analyzing images of remission of structured light by a material to determine sub-diffuse scattering parameters of the material.

Abstract: Disclosed are apparatuses, systems, and techniques to render images depicting light interacting with media that have volume attenuation, using optimized spectral rendering that emulates rendering of the media in tristimulus color rendering schemes.

Abstract: This invention is directed to non-invasive devices and methods to detect electrochemically active molecules in a fluid sample of a subject.

Abstract: A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material.

Abstract: Methods and systems for treating a disease include navigating a symptom-centric decision tree which accounts for probabilities for symptoms and diseases and emergency values for the symptoms and diseases, based on information provided by a user, to determine a disease. A treatment is provided to the user based on the determined disease.

Abstract: A three-dimensional Raman image mapping measuring device for a flowable sample according to an embodiment of the present disclosure is designed to be capable of measuring a flowable sample during mapping measurement of a three-dimensional image that is a region of a confocal Raman by using a micro Raman spectrometer and a three-axis sample stage (Piezo stage). The three-dimensional Raman image mapping measuring device for a flowable sample includes at least one piezo element; an element holder equipped with the piezo element and having an opening, a sample stage for supporting the element holder equipped with the piezo element, an objective lens mounted in the opening in the element holder, a sample holder for controlling vertical movement of the flowable sample disposed under the lower portion of the sample stage, and a transparent window disposed between the sample stage and the sample holder.

Abstract: The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.

Abstract: An optoelectronic sensor module and a method for producing an optoelectronic sensor module are disclosed. In an embodiment an optoelectronic sensor module includes a first semiconductor transmitter chip configured to emit radiation of a first wavelength, a second semiconductor transmitter chip configured to emit radiation of a second wavelength different from the first wavelength, a semiconductor detector chip configured to detect the radiation of the first and second wavelengths, and a first potting body being opaque to the radiation of the first and the second wavelength, wherein the first potting body directly covers side surfaces of the chips and mechanically connects the chips located in a common plane to one another, wherein a distance between the chips is less than or equal to twice an average diagonal length of the chips, and wherein the sensor module is adapted to rest against a body part to be examined.

Abstract: A photoacoustic apparatus includes a light source configured to generate a plurality of pulsed lights in different wavelengths, an irradiation optical system configured to irradiate an object with the pulsed light from the light source and configured to irradiate the object in different irradiation positions along a rotational trajectory during a rotational scanning period in a corresponding wavelength, and a probe configured to receive photoacoustic wave from the object in response to each pulsed light irradiation in the different irradiation positions and to convert the received photoacoustic wave into an electric signal. The irradiation optical system is moved to irradiate the object with a first wavelength in a plurality of times during a first rotational scanning period and irradiate the object with a second wavelength in a plurality of times during a second rotational scanning period after the first rotational scanning period.

Abstract: An apparatus and method for detecting a bio-signal feature are provided. The apparatus according to one aspect may include: a bio-signal acquirer configured to acquire a bio-signal; and a processor configured to generate an envelope signal of the bio-signal, and detect at least one feature of the bio-signal based on a difference between the envelope signal and the bio-signal.

Abstract: A neural sensing system includes an interrogator that includes an optical head. The optical head is configured to transmit a light signal. The neural sensing system also includes a microprobe configured to contact tissue. The microprobe includes a transducer configured to receive the light signal and modulate the light signal with neural signal information sensed from the tissue. The microprobe also includes a retroreflector configured to reflect the modulated light signal back to the optical head of the interrogator.

Abstract: The present invention relates to a parathyroid sensing system, and includes: a modulator for generating a modulation signal having a predetermined frequency; a lock-in amplifier and a light source which receive information on the modulation signal; an excitation filter for transmitting, among light emitted from the light source, only excitation light that excites parathyroid glands; an emission filter connected to a probe and selectively transmitting only fluorescence emitted from the parathyroid glands; a near-infrared sensor for sensing the autofluorescence that has passed through the emission filter, and converting the sensed autofluorescence into an electric signal; and a speaker for generating an alarm through the electric signal. Through the present invention, the locations of the parathyroid glands may be precisely identified even when lights are turned on in an operating room, and convenience may be provided by alerting a surgeon by means of an alarm when the parathyroid glands are detected.

Abstract: A wearable device for healthcare and a method thereof, wherein the device is worn on a finger for measuring the health data of the user, including but not limited to, the heart rate, blood oxygen saturation, etc. The wearing size of the device is adjustable for different sizes of fingers. In one embodiment, the device includes a main body at least partially worn on a digit of a user; at least one physiological sensor attached to the main body for detecting physiological information; and at least two branches coupled to the main body for holding the digit while reducing the movement of the device. At least a part of at least one branch is changeable such that the wearing size of the device is adjustable for different sizes of digits. In another embodiment, at least a part of at least one branch is movable such that the wearing size of the device is adjustable for different sizes of digits.

Abstract: The present disclosure relates to optical methods and devices based on pulsate behavior of blood and optical absorption spectroscopy to measure the level of water and/or other substances or compounds, such as an alcohol or lipid, in the blood and the tissues surrounding blood vessels and arteries.

Abstract: A device includes source and detector sensors. In a specific implementation, the device has two near detectors, two far detectors, and two sources. The two near detectors are arranged closer to the two sources than the two far detectors. A light-diffusing layer covers the two near detectors. The device may be part of a medical device that is used to monitor or measure oxygen saturation levels in a tissue. In a specific implementation, light is transmitted into the tissue and received by the detectors. An attenuation coefficient is first calculated for a shallow layer of tissue. The attenuation coefficient is then used to calculate an attenuation coefficient for a deep layer of tissue.

Abstract: An antioxidant sensor includes a pressure sensor configured to obtain a contact pressure between an object and an optical sensor; the optical sensor configured to, based on the obtained contact pressure exceeding a set threshold pressure, emit a first light of a first wavelength to the object, and receive the first light reflected or scattered from the object; and a processor configured to determine a contact portion of the object in contact with the optical sensor, set a threshold pressure, among different threshold pressures, according to the determined contact portion, and determine an antioxidant value based on the received first light.

Abstract: Techniques for measuring metabolic tissue state and oxygenation in human or animal models, through optical techniques capable of simultaneous measurement at single region of interest. Simultaneously measuring CCO, oxygenated hemoglobin (HbO), and deoxygenated (HbR) hemoglobin is performed and metabolic activity of the tissue is determined. The methods employ a super-continuum light source and a probe to deliver light to the individual, and reflected light from the individual is analyzed to determine the metabolic function of the individual.

Abstract: A system for simultaneously detecting audio-characteristics within a body over multiple body surface locations comprising a coherent light source directing at least one coherent light beam toward the body surface locations, an imager acquiring a plurality of defocused images, each is of reflections of the coherent light beam from the body surface locations. Each image includes at least one speckle pattern, each corresponding to a respective coherent light beam and further associated with a time-tag. A processor, coupled with the imager, determines in-image displacements over time of each of a plurality of regional speckle patterns according to said acquired images. Each one of the regional speckle patterns is at least a portion of a respective speckle pattern. Each regional speckle pattern is associated with a respective different body surface location. The processor determines the audio-characteristics according to the in-image displacements over time of the regional speckle patterns.

Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a fixing indentation containing the sensor, a filler disposed in the fixing indentation to retain the sensor in the holder, and a blocking element disposed between the implantation hole and the fixing indentation to hold the sensor in the holder and restrict the filler in the fixing indentation.

Abstract: An electronic device may include a housing and a PhotoPlethysmoGram (PPG) sensor disposed inside the housing. The PPG sensor may include a first Light Emitting Diode (LED) configured to generate light in a first wavelength band, a second LED configured to generate light in a second wavelength band, a third LED configured to generate light in a third wavelength band, a fourth LED configured to generate light in a fourth wavelength band, and a light receiving module including at least one photo diode. The electronic device may include a processor operatively coupled with the PPG sensor and a memory operatively coupled with the processor. The memory may include instructions that, when executed, cause the processor to measure optical densities of the light generated by the first LED to the fourth LED, and calculate a blood glucose value based at least in part on the measured optical densities.

Abstract: The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue layer, such as the dermis, of a person for analysis in a noninvasive analyte property determination systemy, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.

Abstract: An integrated circuit comprises: at least one photonic layer that includes one or more optical waveguides; a first optical coupler that couples at least a first optical mode outside of the photonic layer to a first waveguide in the photonic layer; a photonic device that includes one or more ports in the photonic layer; a first multi-port optical coupler that includes three or more ports in the photonic layer, including a first port optically coupled to the first optical coupler, a second port optically coupled to a first port of the photonic device, and a third port optically coupled to a first optical reflector configured to send substantially all optical power emitted from the third port of the first multi-port optical coupler back to the third port of the first multi-port optical coupler.

Abstract: The invention relates to the field of laser technology and can be used for more efficient optical pumping of laser media in laser generators and amplifiers. The invention can be used for the efficient optical pumping of practically all types of lasers, provided that the absorption profile of the pumped medium is sufficiently broadband. The invention discloses a method and device for combining at least two laser beams of different wavelengths, the polarization states of which are substantially orthogonal, into an exit beam by using a polarizing beamsplitter which spatially combines two beams in mutually orthogonal polarization states, and then changing the polarization state of one of the beams relative to the other using a spectrally selective polarization filter such that the polarization state of the exit beam becomes substantially identical for all of the wavelengths of the exit beam, thus permitting the subsequent combining thereof with another beam.

Abstract: An apparatus comprising an acoustic transducer arrangement configured to transmit at least one acoustic signal and configured to detect a reflection of said at least one acoustic signal, and a controller configured to determine a time-of-flight of the at least one acoustic signal, the controller further configured to determine at least a first value indicative of temperature based on said time-of-flight of the at least one acoustic signal and calibration information indicative of a relationship between time-of-flight and temperature in a space the apparatus is located.

Abstract: An illustrative wearable brain interface system includes a headgear configured to be worn on a head of a user and a plurality of photodetector units configured to attach to the headgear, the photodetector units each housing a photodetector included in a plurality of photodetectors configured to be controlled by a master control unit to detect photons of light.

Abstract: A biological sensor module includes a light emitter that emits irradiation light with which a living body is irradiated, a light receiver that receives reflected light that is the irradiation light reflected off the living body, and a passage section through which the irradiation light and the reflected light pass. The passage section includes an outer surface section that comes into contact with the living body and an inner surface section that is opposite the outer surface section. The outer surface section has a first convex curved surface that presses the living body, and the inner surface section has a second convex curved surface that collects the reflected light incident on the passage section into a spot on the light receiver.

Abstract: A pulse oximetry system for reducing the risk of electric shock to a medical patient can include physiological sensors, at least one of which has a light emitter that can impinge light on body tissue of a living patient and a detector responsive to the light after attenuation by the body tissue. The detector can generate a signal indicative of a physiological characteristic of the living patient. The pulse oximetry system may also include a splitter cable that can connect the physiological sensors to a physiological monitor. The splitter cable may have a plurality of cable sections each including one or more electrical conductors that can interface with one of the physiological sensors. One or more decoupling circuits may be disposed in the splitter cable, which can be in communication with selected ones of the electrical conductors. The one or more decoupling circuits can electrically decouple the physiological sensors.

Abstract: An earpiece monitor configured to be worn by a subject includes a battery, an earpiece fitting configured to be inserted within an ear canal of an ear of the subject, a reflective pulse oximeter configured to measure pulse rate and pulse intensity of the subject, a motion sensor configured to monitor footsteps and head motion of the subject, a digital memory for storing at least one algorithm, and a processor configured to process signals from the reflective pulse oximeter and the motion sensor using the at least one algorithm to generate as assessment of a health state of the subject. The earpiece fitting is configured to transmit sound to the inner ear or eardrum of the subject. The assessment of the health state of the subject may include an assessment of subject physiological stress and/or an assessment of overall subject health.

Abstract: An oxygen-sensing assembly for attachment to a urinary catheter may include a housing having a flow pathway extending between an inlet end and an outlet end thereof, an oxygen sensor in operable communication with the flow pathway of the housing, the oxygen sensor configured to detect oxygen levels of a fluid flowing through the flow pathway, a flowrate sensor configured to detect a flowrate of the fluid flowing through the flow pathway, and a temperature sensor configured to detect a temperature of the fluid flowing through the flow pathway.

Abstract: An apparatus for estimating bio-information according to an embodiment of the present disclosure includes a processor configured to obtain spectra from an object, obtain a component produced based on a change in pressure applied to the object, correct the spectra based on the obtained component produced based on the change in pressure, and estimate bio-information of the object based on the corrected spectra.

Abstract: Described herein is a monitoring system that includes a foot diagnostic device. The foot diagnostic device is shaped to receive one or both of a user's feet. The foot diagnostic device is equipped with a number of sensors that may work together or separately from each other, which are able to measure different diagnostic attributes of the feet. The system includes a mobile application and the ability to transmit information to the mobile application and other locations such as a physician's office.

Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.

Abstract: Methods and apparatus disclosed herein use a filtering technique to improve the accuracy of the results achieved when processing data provided by a physiological sensor. The disclosed filtering technique corrects many of the accuracy problems associated with physiological sensors, particularly PPG sensors. Broadly, the filtering technique adjusts a current filtered estimate of a physiological metric as a function of a rate limit based on a comparison between an instantaneous estimate of the physiological metric and the current filtered estimate.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: A wearable device for reflecting a fatigue level of a human body is disclosed. The device comprises a physiological signal acquisition module, a signal conditioning module, a parameter extraction module and a decision module. The physiological signal acquisition module is configured to acquire physiological signals of a testee. An output end of the physiological signal acquisition module is connected to an input end of the signal conditioning module. The signal conditioning module is configured to perform signal conditioning on the physiological signals. An output end of the signal conditioning module is connected to an input end of the parameter extraction module. The parameter extraction module is configured to extract time-domain and frequency-domain parameters in a specific time window. An output end of the parameter extraction module is connected to an input end of the decision module. The decision module is configured to decide a fatigue level of the testee.

Abstract: An attachment tape is configured such that a light emitter and a light detector are mounted on the attachment tape and such that the attachment tape is wrapped around a tissue so as to be attached to the tissue. The light emitter is configured to emit light. The light detector is configured to detect the light emitted from the light emitter. A width dimension of the attachment tape is gradually narrowed from one point along a longitudinal direction of the attachment tape toward another point at a distal end of the attachment tape.

Abstract: An apparatus for measuring a body fluid includes: an optical sensor configured to emit light onto an object, receive the light returning from the object, and measure a first intensity of a first wavelength and a second intensity of a second wavelength from the received light; and a processor configured to estimate a body fluid volume of the object based on the first intensity and the second intensity.

Abstract: An in-the-ear hearing aid device is disclosed. The device at least one electro-acoustic transducer, and at least one sensor or at least one active electronic component. The at least one electro-acoustic transducer comprises a capsule enclosing a transducer sound active part and a transducer air volume. The transducer air volume is air volume which is enclosed by said capsule and which is in fluid-connection with said transducer sound active part. At least a portion of said at least one sensor or of said at least one active electronic component is provided within said transducer air volume.

Abstract: An electronic device and method are disclosed herein. The electronic device includes a sensor and a processor. The processor implements the method, including measuring infrared light corresponding to a user using the sensor, and detecting biometric information of the user if the infrared information satisfies a predetermined condition.

Abstract: The non-invasive biolipid concentration meter comprises: an irradiator (2) that emits light at a given intensity toward the inside of a living body from outside; a light intensity detector (3) that is disposed at a given distance from a position (21) irradiated with the light from the irradiator (2) and that determines the intensity of light emitted from the living body; a scattering coefficient calculator (4) that calculates the coefficient of light scattering within the living body on the basis of the light intensity determined with the light intensity detector (3); and a lipid concentration calculator (5) that calculates the lipid concentration in the living body on the basis of the coefficient of light scattering.

Abstract: A hearing aid includes a speaker driver, an optical source secured directly to the speaker driver, an optical detector secured directly to the speaker driver, a first light guide extending outwardly from the optical source and in optical communication with the optical source, and a second light guide extending outwardly from the optical detector and in optical communication with the optical detector. The first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector. The hearing aid may include at least one signal processor configured to process signals produced by the optical detector, and at least one of the following: an accelerometer, a humidity sensor, an altimeter, a temperature sensor.

Abstract: Example apparatuses, systems, and methods for detecting a muscle tissue ischemia event are provided. An example apparatus may include an electromyography (EMG) sensor applied to a patient to detect electrical activity in the muscle tissue. The apparatus may also include processing circuitry in communication with the EMG sensor and configured to receive EMG signals from the EMG sensor and detect characteristics within the EMG signals indicating oxygen depletion within the muscle tissue of the patient. The characteristics may include a signal power level of the EMG signals increasing by at least a threshold value at a select frequency or with respect to a select band of frequencies. The processing circuitry may be further configured to trigger an output, in response to detecting the characteristics, indicating that the oxygen depletion in the muscle tissue is indicative of an ischemia event.

Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient includes an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue. The monitor also includes a perfusion status indicator indicating a perfusion status of the PPG signal, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP value based on a respiratory variation of the PPG signal. The FRP calculator applies a correction factor based on the perfusion status indicator.

Abstract: A biological analysis device includes an average blood pressure calculation unit that calculates an average blood pressure index related to an average blood pressure of a biological body in accordance with a blood vessel diameter index related to a blood vessel diameter of the biological body and a blood flow index related to a blood flow of the biological body and calculated from an intensity spectrum related to a frequency of light reflected and received from an inside of the biological body through radiation of a laser beam.