Glucose Measurement Patents (Class 600/365)
  • Patent number: 11116900
    Abstract: An electronic insulin delivery device receives glucose data from a glucose monitor and sets a bolus dose amount. The device may take the form of an insulin pen with automatic priming and accurate dosing provided by a motor in connection with an encoder. The device may communicate with and be controlled by a smart phone device. The smart phone device provides a user interface to receive user data including patient weight, insulin to carbohydrate ratio and exercise factor, and to send instructions to the device, including dose amount. The dose amount is determined taking into account glucose level and trend, and other factors. The delivery device may be in continuous communication with the glucose monitor and smart phone to provide for near real-time adjustments in glucose treatment. Glucose data, insulin injection data, and other relevant data may be stored and accessible to interested parties.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: September 14, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: M. Ishaq Haider, Noel Harvey, Sundeep Kankanala, Frank Martin, Ronald Pettis
  • Patent number: 11122015
    Abstract: According to an aspect of the invention, a data transmitting apparatus includes a transmitting unit that transmits a first packet through a unidirectional communication based on an instruction to transmit the first packet, and that transmits a second packet through a unidirectional communication based on an instruction to transmit the second packet.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: September 14, 2021
    Assignees: OMRON HEALTHCARE CO., LTD., OMRON CORPORATION
    Inventors: Nobuo Kubo, Toru Deno, Hideki Kondo
  • Patent number: 11090433
    Abstract: An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: August 17, 2021
    Assignee: UNIVERSITY O VIRGINIA PATENT FOUNDATION
    Inventors: Stephen D. Patek, Basak Ozaslan, Linda Gonder-Frederick
  • Patent number: 11058358
    Abstract: An apparatus for providing corrected bio-information by using a bio-information sensor includes a communicator configured to receive bio-information from the bio-information sensor; a processor configured to extract metabolic information based on food intake information of a user and correct the received bio-information based on the extracted metabolic information; and an outputter configured to provide a result of correcting the bio-information.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: July 13, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: So Young Lee, Jin Young Park, Ka Ram Choi, Sang Kon Bae
  • Patent number: 11051726
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: July 6, 2021
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Jack Pryor, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 11013439
    Abstract: Method and apparatus for optimizing analyte sensor calibration including receiving a current blood glucose measurement, retrieving a time information for an upcoming scheduled calibration event for calibrating an analyte sensor, determining temporal proximity between the current blood glucose measurement and the retrieved time information for the upcoming calibration event, initiating a calibration routine to calibrate the analyte sensor when the determined temporal proximity is within a predetermined time period, and overriding the upcoming scheduled calibration event using the current blood glucose measurement are provided.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: May 25, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Erwin Satrya Budiman, Wesley Scott Harper, Timothy Christian Dunn
  • Patent number: 11017899
    Abstract: A diabetes management system includes a handheld medical device, a mobile computing device, and a diabetes management application. The handheld medical device is configured to determine, in response to a port receiving a test strip, whether an auto-send feature is enabled on the handheld medical device, determine whether the handheld medical device is paired with a mobile computing device, and selectively instruct a wireless transceiver to establish a wireless connection and communicate a glucose measurement and identifying information to the mobile computing device. The mobile computing device is configured to execute the diabetes management application. The diabetes management application is configured to process a plurality of glucose measurements and identifying information associated with each of a plurality of glucose measurements.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: May 25, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Eric S. Carlsgaard, David B. Markisohn, Mark Mears
  • Patent number: 11006872
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: May 18, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Phillip Yee, Christopher A. Thomas, Udo Hoss, Lei He, Michael R. Love
  • Patent number: 11006535
    Abstract: Introduced here is an attachable unit that connects to a base unit through a snap-fitting mechanism. The attachable unit can include a top housing structure and a bottom housing structure that are ultrasonically welded together. The top housing structure can include the toe portion that is integral with remaining portions of the top housing structure, where the toe portion is configured to provide the snap-fit with the base unit.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: May 11, 2021
    Assignee: Verily Life Sciences LLC
    Inventors: Arthur Lin, Sean Frick
  • Patent number: 10998101
    Abstract: A method includes capturing continuously vital signs and motion data from one or more sensors adapted to be coupled to a user; capturing food consumption of the user; predicting a predetermined health condition of the user based on the vital signs; generating a plan for the predetermined health condition; and prompting the user to execute the plan with a closed-loop feedback based on sensor data.
    Type: Grant
    Filed: December 15, 2019
    Date of Patent: May 4, 2021
    Inventors: Bao Tran, Ha Tran
  • Patent number: 10985804
    Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: April 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Thomas Miller, Mark Dervaes, Phong Lieu, Peter C. Simpson, Shawn Larvenz, Jacob S. Leach, Sebastian Bohm
  • Patent number: 10980450
    Abstract: Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: April 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Jeffrey R. Wedekind, Douglas William Burnette, Aditya Mandapaka, Zebediah L. McDaniel, Peter C. Simpson, Arturo Garcia
  • Patent number: 10980453
    Abstract: Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Jeffrey R. Wedekind, Douglas William Burnette, Aditya Mandapaka, Zebediah L. McDaniel, Peter C. Simpson, Arturo Garcia
  • Patent number: 10980451
    Abstract: Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.
    Type: Grant
    Filed: September 21, 2020
    Date of Patent: April 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Jeffrey R. Wedekind, Douglas William Burnette, Aditya Mandapaka, Zebediah L. McDaniel, Peter C. Simpson, Arturo Garcia
  • Patent number: 10957438
    Abstract: A method includes obtaining blood glucose measurements and blood glucose times of a patient from a blood glucose meter and executing a patient management program configured to display on a screen a graphical user interface having a trend window of the blood glucose measurements on the time line. The patient management program is configured to receive, in the trend window magnifying inputs for a magnification window superimposed on a segment of the timeline to specify a date range for a magnified window. The patient management program is further configured to display the magnified window including the blood glucose measurements of the patient from the specified date range and display a first information window including quantitative information associated with the blood glucose measurements from the specified date range.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: March 23, 2021
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Robert Salitsky, Andrew Rhinehart
  • Patent number: 10955423
    Abstract: A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: March 23, 2021
    Assignee: The General Hospital Corporation
    Inventors: Roy Malka, John M. Higgins, David M. Nathan
  • Patent number: 10945602
    Abstract: The embodiment of the present disclosure discloses a monitoring parameter threshold value setting method, comprising the following steps: selecting at least one threshold value indicator of the monitoring parameter that needs a threshold value setting; forming and displaying a corresponding threshold value setting graphic according to the said threshold value indicator, wherein, in the said threshold value setting graphic, said threshold value indicator corresponds to an indication icon; responding to the threshold value setting of the threshold value indicator by a user, and adjusting the indication icon corresponding to the threshold value indicator to the corresponding position of the said indicating graphic.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 16, 2021
    Assignees: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD., SHENZHEN MINDRAY SCIENTIFIC CO., LTD.
    Inventor: Jianhui Zhang
  • Patent number: 10943687
    Abstract: An apparatus including a controller can determine a rate of change of a blood glucose level of a patient and generate a pump setting based on the rate of change.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: March 9, 2021
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael L. Blomquist
  • Patent number: 10932672
    Abstract: Systems and methods for remote and host monitoring communication are disclosed. In some implementations, monitoring systems can comprise a host monitoring device associated with a Host communicatively coupled to one or more remote monitoring devices associated with Remote Monitors. The host monitoring device can send communications based at least in part on analyte measurements of a Host sensor and/or other contextual data giving such measurements context. Different remote monitoring devices can receive different communications based at least in part on the role of the respective Remote Monitors relative to the Host. These roles can be reflected in classifications of Remote Monitors.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: March 2, 2021
    Assignee: DexCom, Inc.
    Inventors: Aarthi Mahalingam, Esteban Cabrera, Jr., Basab Dattaray, Rian Draeger, Laura J. Dunn, Derek James Escobar, Thomas Hall, Hari Hampapuram, Apurv Ullas Kamath, Katherine Yerre Koehler, Phil Mayou, Michael Robert Mensinger, Michael Levozier Moore, Andrew Attila Pal, Nicholas Polytaridis, Eli Reihman, Brian Christopher Smith
  • Patent number: 10935511
    Abstract: The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first electrochemical sensor positioned within a conduit adjacent to a second electrochemical sensor and spaced apart from one another at a predetermined distance. The first electrochemical sensor includes an immobilized layer of antibodies. The second electrochemical sensor includes a magnetic field disposed locally around the second electrochemical sensor, and the magnetic field is configured to attract magnetic beads onto a surface of the second electrochemical sensor. The device further includes a scavenging electrode positioned between the first electrochemical sensor and the second electrochemical sensor. The scavenging electrode is configured to prevent crosstalk between the first electrochemical immunosensor and the second electrical immunosensor.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: March 2, 2021
    Assignee: Abbott Point of Care Inc.
    Inventors: Antti Leo Oskari Virtanen, Cary James Miller, Kenneth Harold Hardage
  • Patent number: 10921257
    Abstract: The present disclosure provides a method for mapping one or more analytes that contact a biological structure. The method uses surface-enhanced Raman spectroscopy and includes contacting the biological structure and a metallic nanoparticle. The method further includes collecting a spectrum with a Raman spectrometer. The method further includes determining a location of the analyte along at least one of an x-direction, a y-direction and a z-direction on the structure.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: February 16, 2021
    Assignee: University of Massachusetts
    Inventor: Lili He
  • Patent number: 10890569
    Abstract: A colorimetric array includes a substrate, a first spot on the substrate, and a second spot on the substrate. The first spot includes a first nanoporous pigment that includes a first nanoporous material and a first immobilized, chemoresponsive colorant. The second spot includes a second nanoporous pigment that includes a second nanoporous material and a second immobilized, chemoresponsive colorant. The first nanoporous pigment is different from the second nanoporous pigment.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: January 12, 2021
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Sung H. Lim, Christopher J. Musto, Liang Feng, Jonathan W. Kemling, Kenneth S. Suslick
  • Patent number: 10881334
    Abstract: A method, system, and device for improving the accuracy of a continuous glucose monitoring sensor by estimating a CGM signal at a time t+PH using a value of CGM at time t, using a real-time short-time glucose prediction horizon to estimate the real time denoised CGM value with a noise estimation algorithm.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: January 5, 2021
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Andrea Facchinetti, Giovanni Sparacino, Claudio Cobelli, Boris Kovatchev
  • Patent number: 10877022
    Abstract: An occult blood testing device is disclosed. The occult blood testing device includes a main body, a plurality of ribs, at least one light emitting unit, and at least one light sensing unit, wherein the ribs are disposed on an outer surface of the main body, and the light emitting unit and the light sensing unit are disposed in an accommodation space of the main body. The light emitting unit emits an incident light beam and aims the incident light beam towards a direction of an open end of the main body at a test solution, and the light sensing unit receives a detection light beam formed by the incident light beam that penetrated the test solution. When a filter unit is sleeved over the main body, a part of the filter unit is supported by the ribs and a gap is formed between the filter unit and the outer surface of the main body. Through the gap, gas in the accommodation space of the main body can be expelled to prevent the gas existence from affecting the accuracy of the occult blood test.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: December 29, 2020
    Assignee: Taiwan Redeye Biomedical Inc.
    Inventors: Shuo-Ting Yan, Tsung-Jui Lin, I-Hua Wang
  • Patent number: 10863944
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: December 15, 2020
    Assignee: DexCom, Inc.
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Patent number: 10856783
    Abstract: An electronic device includes a sensor that acquires a pulse wave and a controller that calculates an index based on the acquired pulse wave. The controller estimates the subject's state of glucose metabolism or lipid metabolism using the calculated index.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: December 8, 2020
    Assignee: KYOCERA Corporation
    Inventor: Hiromi Ajima
  • Patent number: 10850033
    Abstract: Presented here are techniques for controlling glucose levels of a patient based on predicted time to a target glucose level. One methodology predicts a trajectory of the blood glucose level based on past observations of the blood glucose level, determines a cost expression based on the trajectory, and affects a future command to an infusion pump to affect a cost value according to the cost expression. Another methodology defines a target blood glucose concentration level for the patient, observes a current blood glucose concentration for the patient based on signals received from a blood-glucose sensor, and predicts a duration of time for the patient's blood glucose concentration to reach the target blood glucose concentration level based on the observed current blood glucose concentration.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: December 1, 2020
    Assignee: Medtronic MiniMed, Inc.
    Inventor: Paul H. Kovelman
  • Patent number: 10825569
    Abstract: The present invention discloses a universal non-invasive blood glucose estimation method based on time series analysis, which comprises 5 steps, i.e., data input and preprocessing, features screening, establishment of single-feature model based on time series analysis, multi-feature fusion, and non-invasive blood glucose estimation. During non-invasive blood glucose estimation, new non-invasive test data is inputted, and the blood glucose estimation series is calculated using related feature information obtained through modeling, single-feature model, and multi-feature fusion model. The estimation method provided in the present invention is easy to execute, and can overcome the delay between changes of physiological parameters of human body and changes of blood glucose, and thereby can obtain more accurate non-invasive blood glucose test results. The estimation method is universal and is applicable to different non-invasive blood glucose monitoring methods.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: November 3, 2020
    Assignees: Global Health Ark Medical Technology (Beijing) Co. Ltd, Tsinghua University
    Inventors: Fei Tang, Zhanxiao Geng, Xiaohao Wang, Yadong Ding, Zhiwei Fan
  • Patent number: 10820841
    Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: November 3, 2020
    Assignee: ABBOT DIABETES CARE INC.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh
  • Patent number: 10813576
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: October 27, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10811133
    Abstract: A dosing controller for administering insulin. The dosing controller includes a data processing device and non-transitory memory in communication with the data processing device. The dosing controller receives blood glucose measurements of a patient from the glucometer, receives patient information, selects a subcutaneous insulin treatment from a collection of subcutaneous insulin treatments based on the blood glucose measurements and the patient information, and executes the selected subcutaneous insulin treatment. Each blood glucose measurement is separated by a time interval and includes a blood glucose time associated with a time of measuring the blood glucose measurement.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 20, 2020
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Harry Hebblewhite
  • Patent number: 10806859
    Abstract: A method may include displaying to a user an interface at which the user inputs a fear of hypoglycemia index (FHI), the FHI corresponding to an acceptable probability of a blood glucose level being below a threshold blood glucose level. The method may also include receiving blood glucose data for a person with diabetes (PWD). The method may additionally include calculating a probability of the PWD having a blood glucose level below the threshold blood glucose level based on the variability of the received blood glucose data. The method may also include setting one or more target blood glucose levels to align the probability of the PWD having a blood glucose level below the threshold blood glucose level with the acceptable probability associated with the user input FHI. The method may additionally include delivering insulin, using the insulin delivery device, based on the target blood glucose level.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: October 20, 2020
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Lane Desborough, Bryan Mazlish
  • Patent number: 10799184
    Abstract: The system and method described herein represent a totally new paradigm for assessing risk in critically ill patients by identifying physiologic patterns associated with a poor outcome. It then uses this information to detect these patterns on future patients, sending alerts to clinicians caring for patients with one or more of them. Moreover, the system and method can be extended to outcomes other than mortality, and can be adapted for use in a specific hospital system's EMR. The “code footprint” for embedding the patterns that indicate a trigger is small and thus favorably suited for embedding into an existing clinical decision support system.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: October 13, 2020
    Assignee: Prescient Healthcare Consulting, LLC
    Inventor: Andrew Alan Kramer
  • Patent number: 10792421
    Abstract: This invention relates to automatic insulin delivery systems and methods of administering insulin. Preferably the systems and methods comprise a predictive feedforward control.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: October 6, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Derrick K. Rollins, Sr., Yong Mei
  • Patent number: 10791969
    Abstract: The present disclosure refers to a method for determining a blood glucose level for a patient, the method comprising detecting a present sensor signal in a present continuous interstitial blood glucose measurement for a patient; providing measurement data representing the present sensor signal; providing sensor signal correction data representing a patient-specific signal correction, the sensor signal correction data being determined from a former interstitial blood glucose measurement for the patient and comprising at least one of time delay data representing a patient-specific time delay ?t between a blood glucose value measured in a continuous interstitial blood glucose measurement and a blood glucose reference value measured in a capillary blood glucose measurement, and sensor sensitivity data representing, for the patient, a patient-specific sensor sensitivity for the sensor, determining corrected measurement data representing a corrected present sensor signal by applying the sensor signal correction dat
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: October 6, 2020
    Assignee: ROCHE DIABETES CARE, INC
    Inventors: Guenther Schmelzeisen-Redeker, Nikolaus Schmitt, Christian Ringemann
  • Patent number: 10780223
    Abstract: A method includes receiving up-to-date blood glucose data for a PWD, determining basal insulin dosages for the PWD based on a baseline basal rate, delivering the basal insulin dosages to the PWD, modifying a target blood glucose level based on variability of blood glucose data for the PWD, receiving a temporary override indicating a user preference to reduce the likelihood that the PWD has a hypoglycemic event or a user preference to reduce the likelihood that the PWD has a hyperglycemic event, determining a temporary target blood glucose level based on the input—greater than the modified blood glucose level if the preference is to reduce the likelihood of a hypoglycemic event—lower than the modified target blood glucose level if the preference is to reduce the likelihood that of a hyperglycemic event. The method includes delivering basal insulin for the temporary period of time based on the temporary target.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 22, 2020
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Lane Desborough, Bryan Mazlish
  • Patent number: 10772552
    Abstract: A wearable device for the quantification of regulatory substances produced in the body, such as analytes and hormones, is disclosed. The wearable device includes contact sensors formed on an outer portion of a casing of the wearable device, and those contact sensors are positioned to contact skin of a wearer of the device and configured to measure galvanic skin response and temperature. The wearable device also includes a microprocessor in the casing of the wearable device adapted to control programs and execute algorithms, a system memory in the casing of the wearable device adapted to store data, an entry port in the casing of the wearable device adapted to receive a biological-assay cartridge containing a biological sample, and a biological-assay reader placed inside the casing of the device and configured to read the biological sample.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: September 15, 2020
    Inventor: Alfred H. Bedell, Jr.
  • Patent number: 10761347
    Abstract: An ophthalmic device includes an enclosure that is compatible for wearing in or on an eye. An adjustable lens is disposed within the enclosure. Driver circuitry is disposed within the enclosure and coupled to drive the adjustable lens and change its optical power. Built-in-self-test (BIST) circuitry is disposed within the enclosure and coupled to the adjustable lens. The BIST circuitry includes an impedance measurement circuit coupled to selectively measure an impedance of the adjustable lens. A controller is disposed within the enclosure and includes BIST control logic that measures the impedance of the adjustable lens with the impedance measurement circuit to determine a health status of the adjustable lens.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: September 1, 2020
    Assignee: Verily Life Sciences LLC
    Inventor: Shungneng Lee
  • Patent number: 10746693
    Abstract: A device includes a biosensor, a sensing circuit electrically connected to the biosensor, a quantizer electrically connected to the sensing circuit, a digital filter electrically connected to the quantizer, a selective window electrically connected to the digital filter, and a decision unit electrically connected to the selective window.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: August 18, 2020
    Assignee: Taiwan Semiconductor Manufacturing Company
    Inventors: Jui-Cheng Huang, Yi-Shao Liu, Chun-Wen Cheng, Tung-Tsun Chen, Chin-Hua Wen
  • Patent number: 10736549
    Abstract: An example continuous glucose monitor includes a printed circuit board (“PCB”) having first and second outer layers and an inner layer; a semiconductor package having a plurality of pins coupled to the first outer layer of the PCB; an electrical contact formed on the second outer layer of the PCB; a trace having a first portion disposed on the first outer layer, a second portion disposed on the inner layer, and a third portion disposed on the second outer layer, the trace having a first end coupled to a first pin of the plurality of pins and a second end coupled to the electrical contact; and an encapsulant disposed around a perimeter of the semiconductor package, the encapsulant covering the plurality of pins, the first portion of the sensor trace, the third portion of the sensor trace, wherein an upper surface of the semiconductor package remains exposed.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: August 11, 2020
    Assignee: Verily Life Sciences LLC
    Inventors: Mandy Philippine, Scott Matula, Johan Vanderhaegen, Louis Jung, Nivi Arumugam
  • Patent number: 10724066
    Abstract: Devices and methods capable of detecting glucose in saliva (FIG. 12). The devices feature a sensor having a substrate containing electrodes and one or more reagents on the electrodes. A detection device is operably coupled with the sensor to detect glucose based on measurement of an electrical parameter when electricity is applied to the electrode.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: July 28, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jeffrey LaBelle, Chi Lin, Jonus Reyna, Amnah Alkhan, Cael Muggeridge, Susan Sheffield
  • Patent number: 10714212
    Abstract: A portable data-management system based on an analyte testing device which communicates wirelessly with a mobile device. The mobile device runs an application to manage and analyze data obtained by the analyte testing device. The mobile device may assist the user in displaying testing data, identifying patterns to assist healthy behavior or issue warnings based on the collected data. The mobile device may be connected to a network to store user health data for use by other parties.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: July 14, 2020
    Assignee: Ascensia Diabetes Care Holding AG
    Inventors: Jun Chen, Harris Lieber, Erik Nelson, Jeffery S. Reynolds, Kevin Curran, Aseem Mehta, Dawn Rountree
  • Patent number: 10709978
    Abstract: An example system includes a physiological sensor for generating physiological data associated with a user bearing the physiological sensor. The physiological sensor is configured to wirelessly communicate the physiological data. A portable device includes a touch input device; an accelerometer for generating accelerometer data indicative of activity of the user; wireless communication circuitry for receiving the physiological data; memory for storing the accelerometer data and the physiological sensor data; and a vibrator for providing tactile output to the user. The wireless communication circuitry transmits the physiological data and the accelerometer data to a computer device for use in a presentation application.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: July 14, 2020
    Assignees: NINTENDO CO., LTD., TOHOKU UNIVERSITY
    Inventors: Makoto Yoshizawa, Tomoyuki Yambe, Norihiro Sugita, Norikatsu Furuta
  • Patent number: 10702165
    Abstract: The invention in at least one embodiment includes a method for determining the core body temperature of a person by setting an initial core body temperature with a processor; receiving a heart rate of the person with the processor; calculating a predicted core body temperature with the processor using an extended Kalman filter based on the heart rate and the initial core body temperature; and providing the predicted core body temperature. In another embodiment, a system for performing the method.
    Type: Grant
    Filed: March 4, 2017
    Date of Patent: July 7, 2020
    Assignee: The Government of the United States, as Represented by the Secretary of the Army
    Inventor: Mark J. Buller
  • Patent number: 10702198
    Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: July 7, 2020
    Assignee: DexCom, Inc.
    Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
  • Patent number: 10653344
    Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 19, 2020
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Gary Alan Hayter
  • Patent number: 10638979
    Abstract: Apparatus and methods for error modeling and correction in a blood analyte sensor or system. In one exemplary embodiment, the apparatus employs: (i) a training mode of operation, whereby the apparatus conducts “machine learning” to model one or more errors (e.g., unmodeled variable system errors) associated with the blood analyte measurement process, and (ii) generation of an operational model (based at least in part on data collected/received in the training mode), which is applied to correct or compensate for the errors during normal operation and collection of blood analyte data. This enhances device signal stability and accuracy over extended periods, thereby enabling among other things extended periods of blood analyte sensor implantation, and “personalization” of the sensor apparatus to each user receiving an implant. In one variant, the blood analyte is glucose, and the implanted sensor utilizes an oxygen-based molecular measurement principle.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: May 5, 2020
    Assignee: GlySens Incorporated
    Inventors: Piyush Gupta, Joseph Lucisano
  • Patent number: 10642960
    Abstract: A system and method for controlling medication-dispensing patches by a wearable device is provided. The method comprises receiving a transmission at a wearable device, wherein the transmission identifies a medication-dispensing patch; transmitting information corresponding to the identified medication-dispensing patch to an external computing device; receiving information at the wearable device from the external computing device, wherein the received information corresponds to a dosage of a medication that should be dispensed by the medication-dispensing patch; and transmitting information from the wearable device, wherein the transmission is configured for controlling a medication dosage that is dispensed by the medication-dispensing patch.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: May 5, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Jonathan T. Goguen
  • Patent number: 10624221
    Abstract: Introduced here is an attachable unit that connects to a base unit through a snap-fitting mechanism. The attachable unit can include a top housing structure and a bottom housing structure that are ultrasonically welded together. The top housing structure can include the toe portion that is integral with remaining portions of the top housing structure, where the toe portion is configured to provide the snap-fit with the base unit.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: April 14, 2020
    Assignee: Verily Life Sciences LLC
    Inventors: Arthur Lin, Sean Frick
  • Patent number: 10617822
    Abstract: Methods, devices, algorithms, and systems controlling insulin delivery employ velocity-weighting. Predicted glucose outcomes are penalized with a cost modulated by a factor that is a function of the glucose velocity, wherein glucose outcomes are penalized increasingly less for increasingly negative glucose velocities, when glucose level is high, and/or wherein a hyperglycemic glucose value that is already converging to the euglycemic zone results in less corrective action by the controller than were the hyperglycemic state steady.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: April 14, 2020
    Assignee: The Regents of the University of California
    Inventors: Ravi L. Gondhalekar, Eyal Dassau, Francis J. Doyle, III