Abstract: A method of enhancing readability of a graph showing glucose values received from a continuous glucose monitoring device (CGM) on the display of a handheld device includes receiving a plurality of CGM glucose values separated by a first fixed time interval. A second fixed time interval at which to display at least a portion of the plurality of CGM glucose values is received. The second fixed time interval is greater than the first fixed time interval. A computer processor of the handheld device determines a characteristic CGM glucose value at a preselected fixed time for each of a sequence of second fixed time intervals within a patient-specified time period. Each characteristic CGM glucose value is derived from two or more received CGM values centered about the preselected fixed time in the corresponding second fixed time interval. The characteristic CGM glucose values for a patient-selected period of time on the display.

Abstract: A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement.

Abstract: A system is provided including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. The data received from the continuous analyte sensor may be used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement. The device may provide for toggling between modes that allow or prevent the display of glucose concentration values associated with the continuous glucose sensor.

Abstract: Techniques for controlling an insulin pump include determining values for parameters selected from a group including a first prediction time horizon, a predicted glucose threshold (Goff) for turning the insulin pump off, a maximum shut off time within a time window, and duration of the time window. A safety rule is determined based on the maximum shut off time within the duration. Glucose readings are collected up to a current time. An expected current glucose value G and glucose temporal rate of change are determined based only on the glucose readings and a Kalman filter configured for noisy glucose readings. A glucose level (Gh1) is predicted for a future time that is the prediction time horizon after the current time. A command is issued to shut off the insulin pump if it is determined both that Gh1 is less than Goff and that the safety rule is satisfied.

Abstract: A device may be implanted subcutaneously with an attached catheter inserted within, e.g., the peritoneal cavity of a subject. The catheter and/or device may also be inserted into another space, e.g., subcutaneous, vascular, peritoneal, cerebrospinal, pleural spaces, etc. The peritoneal fluid which normally collects and/or flows through the peritoneal cavity may be detected by the catheter and analyzed via the device to detect the concentration of glucose within the fluid.

Abstract: A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.

Abstract: A physiological trend monitor has a sensor signal responsive to multiple wavelengths of light transmitted into a tissue site. The transmitted light is detected after attenuation by pulsatile blood flow within the tissue site. A processor has an input responsive to the sensor signal and a physiological parameter output. Features are extracted from the physiological parameter output. Criteria are applied to the features. An alarm output is generated when the criteria are satisfied.

Abstract: In aspects of the present disclosure, an auto turn on blood glucose monitoring unit including a calibration unit integrated with one or more components of an analyte monitoring system is provided. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract: A method for measuring a concentration of a biogenic substance in a living body includes steps of: preparing an apparatus including a light source, a substrate which has periodic metal structures and generates surface enhanced Raman scattering light by being irradiated with light from the light source, and spectroscopic means which disperses and detects the light, wherein the periodic metal structure is arranged with first and second distances in first and second direction respectively, the first distance is set to generate surface plasmon by matching a phase of the light from the light source, and the second distance is smaller than the first distance and is set between 300 nm and 350 nm; irradiating the substrate with the light from the light source to generate the surface enhanced Raman scattering; detecting the scattering with the spectroscopic means; and calculating the concentration of the biogenic substance based on the scattering.

Abstract: This present disclosure relates to systems and methods for providing an Adaptive Analytical Behavioral and Health Assistant. These systems and methods may include collecting one or more of patient behavior information, clinical information, or personal information; learning one or more patterns that cause an event based on the collected information and one or more pattern recognition algorithms; identifying one or more interventions to prevent the event from occurring or to facilitate the event based on the learned patterns; preparing a plan based on the collected information and the identified interventions; and/or presenting the plan to a user or executing the plan.

Abstract: A measuring system for measuring the concentration of substances or analytes in a body fluid or in a body tissue comprises a microdialysis probe comprising a microdialysis membrane, the probe being adapted to be placed in blood or in tissue, a flow through sensor for analysing a fluid having passed the microdialysis probe, a pump for pumping the fluid to and through the microdialysis probe and further to and through the sensor, and tubing connecting the pump to the microdialysis probe and the microdialysis probe to the sensor. The pump effects a flow rate in the system in the interval 0.2-15 microliters per minute. The sensor comprises a flow channel having a flow resistance or pressure drop adapted to the characteristics of the microdialysis membrane so as to eliminate, or at least substantially reduce, ultra filtering in the microdialysis membrane.

Abstract: A testing member for eliciting blood samples is provided that can be rotatably mounted inside a cartridge and having a lancet for lancing a body part of a user. The lancet can protrude from an edge of the testing member. The testing member also can have a second blood collection part, and second contact pads, where the second contact pads being electrically connected to the second blood collection part, the second blood collection part and second contact pads together being configured to facilitate an analysis of the quantity of blood in a first blood sample in the second blood collection part. A blood analysis part and first contact pads can be included, where the first contact pads are electrically connected to the blood analysis part, the blood analysis part and first contact pads together being configured to facilitate an analysis of a second blood sample in the blood analysis part.

Abstract: A biometric monitoring device measuring various biometric information is provided that allows the person to take and/or display a heart rate reading by a simple user interaction with the device, e.g., by simply touching a heart rate sensor surface area or moving the device in a defined motion pattern. Some embodiments of this disclosure provide biometric monitoring devices that allow a person to get a quick heart rate reading without removing the device or interrupting their other activities. Some embodiments provide heart rate monitoring with other desirable features such as feedback on data acquisition status.

Abstract: A modular system and method for testing and measuring various physical and chemical properties of substances includes a user interface unit having a micro controller, a power source, a display, and an input device; and a sensing module having a sensor probe, a signal conditioner, and a sensor controller. The user interface unit and the sensing modules are in electrical communication with one another such that sensor data generated by the one or more sensor probes, corresponding to one or more properties of the substances, is transmitted to the micro controller of the user interface unit. The user interface unit can be used to remotely view, test, record, and analyze data obtained by the sensing module, which module may be located at a remote location. The user interface unit and the sensing module may be in wired or wireless communication according to various known wired and wireless connection means.

Abstract: In a combination invasive and non-invasive bioparameter monitoring device an invasive component measures the bioparameter and transmits the reading to the non-invasive component. The non-invasive component generates a bioparametric reading upon insertion by the patient of a body part. A digital processor processes a series over time of digital color images of the body part and represents the digital images as a signal over time that is converted to a learning vector using mathematical functions. A learning matrix is created. A coefficient of learning vector is deduced. From a new vector from non-invasive measurements, a new matrix of same size and structure is created. Using the coefficient of learning vector, a recognition matrix may be tested to measure the bioparameter non-invasively. The learning matrix may be expanded and kept regular. After a device is calibrated to the individual patient, universal calibration can be generated from sending data over the Internet.

Abstract: The present invention recognizes that there is a need for a single-step, pain-free or substantially pain-free device to test the levels of an analyte in one's blood such as glucose. The invention incorporates a lancet and a glucose test strip into a disposable cartridge. The user inserts the cartridge into the port of the device to turn it on. The base vibrates to quench or reduce pain from a lancet puncture. The test strip is exposed to the blood sample at the site of the lancet puncture which is analyzed by the device.

Abstract: Disclosed are methods, apparatuses, etc. for glucose sensor signal reliability analysis.

Abstract: A device is provided for determining blood glucose characteristics including a display configured for presenting a graphical representation of a plurality of measurements of blood glucose values, wherein the graphical representation comprises a trend indicator indicating an approximate value trend in the sensed blood glucose value over a recent series of measurements, based on graphical segments having different graphical styles assigned to different ranges of sensed blood glucose values to indicate a transition from a first range to a second range of sensed blood glucose values. An associated method for operating a device for determining blood glucose characteristics is also provided.

Abstract: There are included: a step for receiving, through communication, pieces of operation information each including (a) operating state information of a device and (b) user information for identifying a user, in association with each other; a step storing the pieces of the operation information received in the receiving into a first storage unit; a step for reading, from a second storage unit, behavior tendency information including, in association with each other, (c) operating state information of at least one device and (d) a predetermined user behavior tendency of the user; and a step for specifying the predetermined user behavior tendency which corresponds to the operating state information of at least one device, by searching the pieces of the operation information for the operating state information of at least one device which is included in the behavior tendency information.

Abstract: One or more therapeutic fluids, such as for example insulin can be delivered to a body. In addition or alternatively, the concentrations of one or more analytes can be measured in vivo. A feedback process can be used to regulate levels of the one or more analytes based on the measurements via delivery of the one or more therapeutic fluids. Related systems, apparatus, methods, and/or articles are also described.

Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated.

Abstract: A detection device for detecting a blood count parameter in a blood vessel, comprising a transmitter having a number of transmit antennas for transmitting at least one transmit signal, a receiver having a number of receive antennas for receiving at least one receive signal, a processor to select a detection configuration comprising one of the transmit antennas and one of the receive antennas and select a second detection configuration comprising one of the transmit antennas and one of the receive antennas, and a loss detector that is designed, when the first detection configuration is selected to transmit a transmit signal, to detect a first loss value on the basis of the transmit signal and a receive signal, and, when the second detection configuration is selected to transmit a transmit signal, detect a second loss value on the basis of the transmit signal and a receive signal. The processor is designed to select the detection configuration having the lower loss value to detect the blood count parameter.

Abstract: Methods and apparatus for providing multi-stage signal amplification in a medical telemetry system are provided.

Abstract: An integrated-testing system includes a meter, a lancing device and a storage case. The meter includes a housing, a display and a processor. The storage case holds the meter and the lancing device in a relatively fixed position to each other. The meter and the lancing device are maintained in the storage case in the relatively fixed position until a fluid sample is desired, at which time a first portion of the lancing device is advanced to a position external to the storage case to obtain the fluid sample and a second portion of the lancing device remains relatively fixed in the storage case while the fluid sample is obtained.

Abstract: A method and an apparatus for measuring glucose level in the body fluid of a subject, typically blood glucose level, by measuring impedance of a body tissue, with two pairs of electrodes, two electrodes for injecting current into a body tissue and two electrodes for detecting the ensuing voltage of the body tissue. The body tissue is typically a sub-dermal or sub-cutaneous tissue. The measured impedance of the body tissue is used to correlate with directly determined glucose levels to determine the glucose level from the measured impedance. It is thus possible to determine body fluid glucose levels in a reliable and reproducible manner.

Abstract: A testing system and method for providing a testing system includes a user interface having a display for displaying information relating to measurements of health data and an input device for receiving information from a user relating to the health data. Provided in connection with the user interface is an autologging feature adapted to provide the user with user-selectable options on the display. Also provided is a statistical operation adapted to provide the user with enhanced information relating to the measurements of health data. Also provided is at least one indicator for indicating information relating to the number of health data readings that are within a target range, the number of health data readings that are above the target range and the number of health data readings that are below the target range.

Abstract: Devices and methods for providing a user with alerts are provided. The alerts may take different forms, such as an output to a display, a speaker, a vibration module, a shock module, etc. The alerts provide the user with sufficient information to take appropriate action, but the devices may be of limited functionality to enhance their compactness, discreetness, wearability, etc., while also lowering their cost to manufacture.

Abstract: The invention relates to a method for calibrating an analyte-measurement device that is used to evaluate a concentration of analyte in bodily fluid at or from a measurement site in a body. The method involves measuring a concentration, or calibration concentration, of an analyte in blood from an “off-finger” calibration site, and calibrating the analyte-measurement device based on that calibration concentration. The invention also relates to a device, system, or kit for measuring a concentration of an analyte in a body, which employs a calibration device for adjusting analyte concentration measured in bodily fluid based on an analyte concentration measured in blood from an “off-finger” calibration site.

Abstract: Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device.

Abstract: A device for detection or measurement of a carbohydrate analyte in fluid comprises: an optical sensor comprising components of an assay for carbohydrate analyte, the readout of which is a detectable or measurable optical signal, and a light guide having a distal portion optically coupled to the assay components and a proximal portion; and a reader for interrogating the optical sensor, the reader comprising an assay interrogating system including a lens; and an interface portion forming part of at least one of the optical sensor and the reader, the interface portion being capable of removably constraining the proximal portion of the light guide and the lens of the assay interrogating system in an optically coupled arrangement. The device may be combined with an insulin-infusion system.

Abstract: Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device.

Abstract: A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g., glucose) in the body fluid is then determined. It is found that the stimulation of the skin provides results that are generally closer to the results of measurements from the fingertips, the traditional site for obtaining body fluid for analyte testing.

Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern.

Abstract: The present invention relates to a blood glucose monitoring system, a strip accommodation device, a strip storage device, and an automated blood collection device, wherein the blood glucose monitoring system has the strip accommodation device formed integrally therewith, the strip accommodation device being configured to convert a rotary motion of a cover of an operating member into an upward linear motion and to eject one of a plurality of strips through an ejection hole, thereby easily storing the strips therein, preventing the contamination of the strips from the foreign matters like outside moisture, and accurately and easily measuring the concentration of the glucose in the blood.

Abstract: Wireless molecular sensor methods and systems integrate radio frequency (RF) technology to interrogate, power, operate and/or readout signals corresponding to levels of molecules of interest from microelectromechanical systems (MEMS) implanted within the body. Various alternative embodiments are disclosed.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: A method detects a biological condition and detects a change in the biological condition of a mammal. The device determines if the change in the biological condition exceeds a predetermined threshold and sends a signal based at least in part on the determination.

Abstract: An intelligent temperature sensing apparatus contains a temperature sensor having a first end for inserting into at least one ear and a second end for connecting with a smartphone; the smartphone in which a control software is loaded and saved; the control software for controlling a processor, an editor, and a storage device. The processor connects with the temperature sensor so as to process at least one measured temperature transmitted from the control software, the editor is used to edit/transform the at least one measured temperature, and the store device is served to record and store the at least one measured temperature.

Abstract: Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.

Abstract: Methods, sensors, and systems that prevent or reduce data loss when more than one external sensor transceiver is used with a sensor. A sensor may receive a transceiver identification (ID) of an external transceiver conveyed from the external transceiver and determine whether the received transceiver ID is a new transceiver ID. If sensor determines the received transceiver ID to be a new transceiver ID, the sensor may store the received transceiver ID in a nonvolatile storage medium of the sensor and convey, using the sensor, measurement information stored in the nonvolatile storage medium to the external transceiver.

Abstract: A calibration system is disclosed for calibrating a first physiological monitoring device using a second physiological monitoring device. The first physiological monitor measures a first indication of a physiological parameter. The second physiological monitor measures a second indication of the physiological parameter. The first and second indications are used to calibrate the first physiological monitoring device.

Abstract: Methods and systems for providing data communication in medical systems are disclosed.

Abstract: In aspects of the present disclosure, a multi compatible or universal blood glucose monitoring unit including a calibration unit is integrated with one or more components of an analyte monitoring system to provide compatibility with in vitro test strip that require calibration code and test strips that do not require calibration code. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract: Methods and apparatus for providing a power supply to a device, including an inductive rechargeable power supply for a data monitoring and management system in which a high frequency magnetic field is generated to provide power supply to a rechargeable power source such as a battery of a transmitter unit in the data monitoring and management system are provided.

Abstract: An apparatus and system diabetes management.

Abstract: The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Abstract: This document relates to receiving and processing signals during cardio-pulmonary resuscitation (CPR) treatment. This document further relates to establishing a localized, patient-specific network for communication of information from one or more sensors to a computing device.

Abstract: Methods and systems for providing therapy related data management are provided. The subject systems include one or more device components, and at least one memory storage unit and at least one data storage unit associated with such one or more device components. The device components may include one or more of an analyte monitoring system, a fluid delivery device and a remote terminal. The subject methods include use of the subject systems to optimize treatment of a patient.