Abstract: A method of compensating for breathing and other motions of a patient during treatment includes periodically generating internal positional data about an internal target region. The method further includes continuously generating external positional data about external motion of the patient's body using an external sensor and generating a correlation model between the position of the internal target region and the external sensor using the external positional data of the external sensor and the internal positional data of the internal target region. The method further includes predicting the position of the internal target region at some later time based on the correlation model.

Abstract: An integrated Positron Emission Tomography (PET)/Computed Tomography (CT) system includes a patient support device supporting a patient pallet, a gantry having a space through which the patient pallet passes, a plurality of integrated PET/CT detector modules attached to one side of the gantry, an x-ray tube attached to the other side of the gantry, and a signal detecting/processing unit. Each of the plurality of integrated PET/CT detector modules include a plurality of PET detectors, a flat-panel x-ray detector disposed in contact with the PET detectors and a read-out driver mounted at a rear end of the PET detectors and electrically connected with the flat-panel x-ray detector.

Abstract: The invention comprises a semi-vertical patient positioning, alignment, and/or control method and apparatus used in conjunction with charged particle or proton beam radiation therapy of cancerous tumors. Patient positioning constraints are used to maintain the patient in a treatment position, including one or more of: a seat support, a back support, a head support, an arm support, a knee support, and a foot support. One or more of the positioning constraints are movable and/or under computer control for rapid positioning and/or immobilization of the patient. The system optionally uses an X-ray beam that lies in substantially the same path as a proton beam path of a particle beam cancer therapy system. The generated image is usable for: fine tuning body alignment relative to the proton beam path, to control the proton beam path to accurately and precisely target the tumor, and/or in system verification and validation.

Abstract: A catheter (700, 800, 1206) comprising: a shaft with distal (808, 906, 1004, 208) and proximal ends (1006),wherein the distal end comprises at least one array of capacitive micromachined ultrasound transducers (308, 402, 404, 500, 512, 600, 604, 802, 008) with an adjustable focus for controllably heating a target zone (806, 1014, 1210); and a connector (1012) at the proximal end for supplying the at least one array of capacitive micromachined ultrasound transducers with electrical power and for controlling the adjustable focus.

Abstract: Approaches for assessing hemodynamic characteristics for an organ of interest are related. In one implementation, a fluid dynamics model may be provided with data derived from an anatomic imaging modality and blood flow information derived by ultrasound to derive the desired hemodynamic characteristics. In one such implementation, a fractional flow reserve is estimated.

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, side-loading electrical connectors for use with intravascular devices are provided. The side-loading electrical connector has at least one electrical contact configured to interface with an electrical connector of the intravascular device. A first connection piece of the side-loading electrical connector is movable relative to a second connection piece between an open position and a closed position, wherein in the open position an elongated opening is formed between the first and second connection pieces to facilitate insertion of the electrical connector between the first and second connection pieces in a direction transverse to a longitudinal axis of the intravascular device and wherein in the closed position the at least one electrical contact is electrically coupled to the at least one electrical connector received between the first and second connection pieces.

Abstract: Controlled local application of drugs to a certain part of a body of a patient may be of major importance during a cardiac CT scan. By transporting the drugs in containers which prevent an application of the drugs and by rupturing only those containers which are located in the vicinity of the part of the body of a patient to which the drugs have to be applied, a local application of the drugs may be performed. According to an exemplary embodiment of the present invention, the rupturing and therefore the application of the drugs may be triggered by a monitoring algorithm which evaluates changes in the heart beat rate of the patient. Advantageously, the method allows for a local delivery of the drugs on a fine time scale and therefore for a fast control of the heart beat rate during the CT scan.

Abstract: A medical apparatus (400) comprising an ultrasound transmitter (444, 602) and receiver (446, 604) system (600) for acquiring ultrasound data (476) descriptive of the speed of ultrasound (304, 306) along at least two paths (606, 1114). The medical apparatus further comprises a medical imaging system (402) for acquiring medical image data (468) and a memory (464) containing instructions (490, 492, 494, 496, 498, 500, 502, 504) that causes the processor to acquire (100, 200) the medical image data. The instructions further cause the processor to acquire (102, 202) the ultrasound data. The instructions further cause the processor to segment (104, 204) the medical image data into at least two tissue types (434, 436, 610, 612, 708, 710). The instructions further causes the processor to determine (106, 206) at least two distances corresponding to the at least two paths in the subject. The instructions further cause the processor to calculate (108, 208) the speed of ultrasound in the at least two tissue types.

Abstract: When generating a projection image which is an image formed of image information on a plurality of visual lines viewing a first structure in a three-dimensional medical image from a given viewpoint being projected on a given projection plane, setting an assumed position of a treatment tool in the three-dimensional image, detecting a surface of the first structure from the three-dimensional medical image, identifying a second structure in the three-dimensional medical image located at a position masked by the first structure, detecting an intersection point between an assumed path formed when the treatment tool is moved from the assumed position towards the second structure and the surface of the first structure, and displaying the intersection point in an identifiable manner at a position to which image information on a visual line connecting the viewpoint and the intersection point is projected.

Abstract: A method is disclosed for assisting in determination of the suitability of a patient for a scan of the heart of the patient using an X-ray computer tomograph. In at least one embodiment of the method, a) an electrocardiogram of the patient is recorded; b) the electrocardiogram is evaluated by predicting the occurrence time of at least the immediately following R wave on the basis of at least four immediately consecutive R waves of the electrocardiogram which were measured last, and comparing this with the actual measured occurrence time of the next R wave; and c) wherein the quality of the prediction is visualized qualitatively. Further, in at least one embodiment, a device is disclosed including an ECG instrument and a computation device for carrying out the method. At least one embodiment of the invention furthermore relates to a method and a device for scanning the heart of a patient on the basis of a prediction of R waves.

Abstract: The present invention discloses a neuronavigation-guided focused ultrasound system and a method for the same, which are used to guide focused ultrasound energy to a target point. The system of the present invention comprises a focused ultrasound device, a neuronavigation system and a fixture. According to an image of an interested region of an individual, a focus point of the focused ultrasound device, and tracking points provided by the neuronavigation system, the neuronavigation system performs a calibration process and establishes a positional relationship between the focus point and the image of the interested region. Thereby, the neuronavigation system can recognize the focus point and guide focused ultrasound to the target point.

Abstract: An imaging apparatus in accordance with the present invention comprises a hand-held, battery powered imaging device that provides: (1) an Identification Picture wherein an image of the patient's face is captured for identification purposes; (2) an Area of Interest picture wherein an image of the general area of interest on the patient is captured; and (3) a Subject of Interest picture wherein an image of the subject lesion of interest is captured. Two digital imaging systems, including a wide-angle (e.g. fisheye) imaging system and a macro (close-up) imaging system, are provided to allow for the simultaneous capture of AOI and SOI images thereby capturing an image that identifies the location of the lesion on the body and an image that comprises a close-up view of the lesion. A light source or flash provides illumination during the image capture phase.

Abstract: A method of thermally inducing and monitoring changes to localized regions of tissue by illuminating a volume of tissue with a first beam of X-rays, detecting portions of the first beam that passed through the volume, generating a first image signal from the portions of the first beam detected, applying heat to at least a localized region of tissue within the volume after the illuminating and detecting, illuminating the volume with a second beam of X-rays, detecting portions of the second beam that passed through the volume during the illuminating with the second beam, generating a second image signal from the portions of the second beam detected, and generating a difference image signal based upon a comparison of the first and second image signals. The difference image signal provides information of changes in X-ray attenuation by localized regions of tissue within the volume due to the application of heat.

Abstract: In one embodiment, the present application is directed to a method. The method includes performing at least one of, or a portion of one of, a vertebroplasty procedure, a kyphoplasty procedure, an electroencephalography (EEG) procedure and intraoperative electromyography (EMG) on a patient, and using an imaging system to image at least a portion of the patient during performance of at least a portion of this procedure), the imaging system being arranged on a robot including at least four, preferably six axes of rotation. In another embodiment of the present application, an x-ray system is disclosed. The x-ray system includes an imaging system including an x-ray source and an x-ray detector; a table; and at least two robots. The table is movable by the at least one robot and the at least one other robot includes at least four, preferably six axes of rotation and controls movement of the imaging system.

Abstract: Embodiments provide dual modality probes for imaging phosphatidylserine (PS) exposure and other anionic membrane surfaces. In various embodiments, the probes were constructed by utilizing a) the high selectivity of synthetic zinc (II) dipicolylamine coordination complexes (Zn-DPA) for targeting externalized PS which over-expresses in apoptotic and necrotic cells, b) a near-infrared (NIR) dye for optical imaging, and c) a widely used clinically approved radionuclide for PET (or SPECT) imaging. A variety of linking elements were incorporated into the probes between the Zn-DPA and radionuclide motif to modulate the pharmacokinetics. The in vitro and in vivo data of radiolabeled dipicolylamine probes demonstrated their utilities for imaging PS exposure with multiple imaging modalities.

Abstract: The present invention discloses an imaging device within an MRI. In a magnetic resonance imaging system, a spatially fixed coupled imaging device (SFCID) for producing combined anatomical and real time functional light images, the SFCID functionally incorporates a maneuverable imaging system MIS with a coupled imaging system CIS.

Abstract: A navigation system for catheter-based interventions, the system comprising a processing device; an angiogram x-ray system connected by data transfer connection to the processing device and capable of capturing angiographic images of a patient; an electrocardiogram monitoring device that is also connected by data transfer connection to the processing device and to the x-ray system; a medical instrument to be inserted into the area of the patient captured by the angiographic image; a position capture module for getting position information about the position of the medical instrument, the unit connected by data transfer connection to the processing device, wherein the processing device is capable of triggering the capturing of the angiographic images as a roadmap and superimposing on the roadmap the position information about the medical instrument.

Abstract: A three-dimensional transurethral ultrasound system includes a transurethral ultrasound probe, an ultrasound data processor configured to communicate with the transurethral ultrasound probe to receive ultrasound signals from the transurethral ultrasound probe and to output ultrasound imaging signals for three-dimensional ultrasound images of at least a portion of a patient's prostate, and a display system configured to communicate with the ultrasound data processor to receive the ultrasound imaging signals and to render three-dimensional ultrasound images of the at least the portion of the patient's prostate from the ultrasound imaging signals.

Abstract: A system and method for use in tissue analysis and therapy. An optical probe array has at least two or more optical probes for illuminating tissue and generates light fluorescence and/or diffuse reflectance signals corresponding to the illuminated tissue. One or more ultrasound, CT and MRI imaging guidance systems identify the position of the optical probes relative to the tissue. The imaging guidance system can also be a fusion of an MRI or CT image provided by the MRI or CT imaging guidance system and an ultrasound image provided by the ultrasound imaging guidance system. An imaging system generates a three-dimensional image of the tissue based on the generated light signals and the identified position of the optical probes.

Abstract: A method and apparatus are presented for acquiring MR cardiac images in a time equivalent to a single breath-hold. MR data acquisition is segmented across multiple cardiac cycles. MR data acquisition is interleaved from each phase of a first cardiac cycle with MR data from each phase of a subsequent cardiac cycle. Preferably, low spatial frequency data are interleaved between multiple cardiac cycles, and the subsequent cardiac cycle acquisition includes sequential acquisition of high spatial frequency data towards the end of the acquisition window. An MR image can then be reconstructed with data acquired from each of the acquisitions that reduce ghosting and artifacts. Volume images of the heart can be produced within a single breath-hold. Images can be acquired throughout the cardiac cycle to measure ventricular volumes and ejection fractions. Single phase volume acquisitions can also be performed to assess myocardial infarction.

Abstract: A system for providing automatic diagnosis and decision support includes: a medical image database; generative learning and modeling modules that build distributional appearance models and spatial relational models of organs or structures using images from the medical image database; a statistical whole-body atlas that includes one or more distributional appearance models and spatial relational models of organs or structure, in one or more whole-body imaging modalities, built by the generative learning and modeling modules; and discriminative learning and modeling modules that build two-class or multi-class classifiers for performing at least one of organ, structure or disease detection or segmentation.

Abstract: Presented herein are methods, systems, devices, and computer-readable media for image guided surgery. The systems herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound wands or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets. Additionally, some embodiments provide for quickly calibratable surgical instruments or attachments for surgical instruments.

Abstract: An apparatus includes a diagnostic scanner (102) and a treatment planner (112). The treatment planner (112) plans a treatment to be applied to an object. A treatment device (114) treats the object according to the treatment plan. A treatment scanner (108) scans the object during a treatment session. A motion modeler (116) uses information from the treatment scan to model a motion of the object. A motion compensated quantitative data generator (1004) uses data from the diagnostic (102) or other scanner, as well as feature geometry (1008) and feature motion (1006) information, to generate motion compensated quantitative data indicative of a feature of the object.

Abstract: To visually support a catheter ablation in the heart, three-dimensional image data have been used prior to the intervention. During ablation, the position of the catheter is pinpointed by an orientation system. The orientation system acquires electroanatomical 3D mapping data. The two-dimensional image data is assigned to the 3D mapping data in the correct position and dimensions which is a time-consuming step. The invention makes provision for the orientation system being in a fixed location relative to the X-ray system so that a positionally and dimensionally correct alignment of the X-ray image data set with the 3D mapping data is no longer required. An image or surface based 3D-3D alignment of the three-dimensional data acquired prior to the intervention with the three-dimensional X-ray image data is considerably less time-consuming than alignment thereof with the 3D mapping data and is more reliable because more structures is recognized in the three-dimensional X-ray image data.

Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.

Abstract: Systems and methods for creation of a videographic representation of a real-time medical treatment by a processor operating in conjunction with a treatment device and an imaging device are described. The representation may include real-time imaging data, a representation of real-time treatment data and contours of relevant anatomy among other things. Related systems and techniques are also described.

Abstract: Assemblies are provided for use as surgical instruments in optical coherence tomography (OCT) assisted surgical procedures. Each assembly includes a working assembly, formed from a material selected for desirable optical properties or modified to increase the visibility of the material in an OCT scan, and a handle attached to the working assembly.

Abstract: The invention relates to a method and a device for making correction information for correcting a guidance direction of an instrument. Based on a current position of the tip of the instrument and the current guidance direction of the instrument and the position of a target point in an object, a first straight line indicating the current guidance direction and a second straight line defined by the tip of the instrument and the target point in the object are determined. The second straight line intersects the first straight line and indicates the desired guidance direction. Based on the position of the first and second straight lines relative to one another, a digital item of correction information is specified, wherein the correction image has a correction diagram located in a plane in the perspective of the current guidance direction of the instrument.

Abstract: A miniature surgical robot is attached directly to the bone of a patient at a surgical site, thereby locating the robot precisely on the bone. Intraoperative two-dimensional images of the robot on the bone together with an image referencing element disposed in a predetermined position relative to the robot, are correlated to form a three dimensional image. One or more windows of this three dimensional image are registered with similarly located windows in a preoperative three-dimensional image of the surgical site, the preoperative image including details of the surgeon's plan. This registration of these windows defines the referencing element position in the preoperative image, and hence the robot location in the preoperative image. This enables the robot to be directed to pre-operative determined positions based on the pre-operative plan to perform a surgical procedure.

Abstract: A biopsy system includes a tomographic image pick-up device which is insertable into a living body to pick-up a tomographic image of a bioptic target part in the living body to be subjected to biopsy, a guide wire configured to puncture the bioptic target part in the condition where the tomographic image obtained by the tomographic image pick-up device is being observed; and a biopsy device which is inserted along the guide wire to the bioptic target part in the living body after withdrawal of the tomographic image pick-up device out of the living body and by which tissue of the bioptic target part is sampled. The guide wire remains in the living body in the state of puncturing the bioptic target part even after the withdrawal of the tomographic image pick-up device.

Abstract: A method and system for co-registration of angiography data and intra vascular ultrasound (IVUS) data is disclosed. A vessel branch is detected in an angiogram image. A sequence of IVUS images is received from an IVUS transducer while the IVUS transducer is being pulled back through the vessel branch. A fluoroscopic image sequence is received while the IVUS transducer is being pulled back through the vessel branch. The IVUS transducer and a guiding catheter tip are detected in each frame of the fluoroscopic image sequence. The IVUS transducer detected in each frame of the fluoroscopic image sequence is mapped to a respective location in the detected vessel branch of the angiogram image. Each of the IVUS images is registered to a respective location in the detected vessel branch of the angiogram image based on the mapped location of the IVUS transducer detected in a corresponding frame of the fluoroscopic image sequence.

Abstract: A system for collecting data elements relating to events in an interventional procedure includes an input, a clock, a memory and a display. The input, during the interventional procedure, receives the data elements from at least two systems use in the interventional procedure. The clock registers a time of receipt of the data elements. The memory stores items relating to respective events, each item including the corresponding data element and the corresponding time of receipt. The display displays representations of the items sequentially along a timeline in accordance with the respective times of receipt.

Abstract: In accordance with at least some embodiments of the present disclosure, a medical device for aiding a medical procedure is disclosed. The medical device contains a vibratory component configured to generate vibrations. The medical device also contains an illumination component configured to generate lights. The medical device further contains a contact component coupled with the vibratory component and the illumination component, wherein the contact component is adapted to maintain contact with a skin area, transmit the vibrations to the skin area, and direct the lights to the skin area.

Abstract: In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.

Abstract: An ultrasound system has an ultrasound transducer equipped with a position marker and a needle equipped with a position marker. The position markers allow the position and orientation of the transducer and needle to be determined. Displays indicating a projection of the longitudinal axis of the needle onto a plane of an ultrasound image acquired via the transducer and displays indicating a projection of a reference position onto a plane of an ultrasound image acquired via the transducer are provided. Displays indicating in real-time whether the needle is substantially within the plane of the ultrasound image are provided.

Abstract: Segmentation is provided in multi-modal reconstruction of functional information. Rather than using HU values for segmentation, the HU values are converted into linear attenuation coefficients, such as in a ?-map (Mu map). The conversion uses different functions for different ranges of the HU values. Linear attenuation coefficients are less likely subject to variation by patient, protocol, or scanner. The resulting segmentation may be more consistent across various clinical settings, providing for more accurate multi-modal reconstruction.

Abstract: According to an exemplary embodiment of the present invention, a cardiac roadmapping technique is provided, that does not rely on the prerequisite of a phase-centric pairing of the angiogram and life images. Instead, both the pairing and accurate registration of the images are combined within a single operation, for example by using a multi-device map. This may provide for robust and precise cardiac roadmapping.

Abstract: When estimating an arterial input function or a patient under study, cross-calibration factors are generated by comparing nuclear scan data of a radioactive material (e.g., F18) and measuring a sample of the radioactive material in a gamma counter. The derived cross-calibration factors are applied to venous samples collected from the patient during a nuclear scan after infusion with a radioactive tracer, to convert gamma values counted by the gamma counter into concentration values. The concentration values are used to optimize an initial estimated input function, thereby generating an arterialized input function.

Abstract: A non-contact apparatus for monitoring cardiopulmonary activity signals comprises a pulse-series generator configured to generate a series of probing pulses and a series of reference pulses, a transmitting antenna configured to emit the probing pulses to a chest portion and a series of scattered pulses generated from the probing pulses by the scattering of the chest portion, a receiving antenna configured to receive the scattered pulses, a mixer including a first input port configured to receive the reference pulses and a second input port electrically connected to the receiving antenna and a signal-processing module configured to generate cardiopulmonary activity signals after the scattered pulses and the reference pulses are processed by the mixer.

Abstract: The invention relates to an X-ray device (2) for a medical workplace (1, 21). The X-ray device (2) comprises a robot (R) with a plurality of axes (9), a control device (10) for controlling the axes (9) for movement of the robot (R), and a fastening device (8), and a support device (11) disposed at the fastening device (8), said support device comprising an X-ray radiation source (12) and an X-ray radiation receiver (14). A 3D model (15, 15a) of the robot (R) and the support device (11) provided is stored in the control device (10), said 3D model modeling the spatial extension of the robot (R) and the support device (11) during movement of the robot (R). The 3D model (15,15a) also models the spatial extension of at least one other device (3, 4, R2) of the medical workplace (1, 21) and/or of a living organism (5) located within the medical workplace (1, 21).

Abstract: An imaging and diagnostic system and method to differentiate between malignant and non-malignant tissue of a prostate and surrounding region. The system acquires imaging data from the prostate and surrounding proximal region, and processes the data to differentiate areas of tissue malignancy from non-malignant tissue. A sectioning device or ablative device is provided. The ablative device is operable by automation for receiving the imaging output coordinates and defining the trajectory and quantity of energy or power to be delivered into the malignant tissue. A control system determines calculated energy or power to be deposited into the malignant tissue during ablation, to minimize destruction of the non-malignant tissue within the prostate and surrounding tissue. The system operates on generated ablative device output data.

Abstract: The present invention relates to a system for performing and monitoring minimally invasive interventions with an x-ray unit, in which at least one x-ray source and one x-ray detector can traverse a circular track through an angle range, an ECG recording unit, an imaging catheter, a mapping unit with a mapping catheter and an ablation unit with an ablation catheter. The system comprises a control and evaluation unit with interfaces for the units and catheters, which enable an exchange of data with the control and evaluation unit. The control and evaluation unit is designed for processing measurement or image data which it receives from the catheters and units, and for controlling the catheters and units for the capture of the measurement or image data. The workflow from the examination through to the therapy, particularly with regard to the treatment of tachycardial arrhythmias, is covered completely and continuously by the proposed system.

Abstract: A method includes fitting a motion map from a first imaging modality with a first FOV to a second imaging modality different from the first with a second FOV sized differently than the first FOV.

Abstract: A facility for performing a medical examination includes a room, a medical imaging system located in the room, and a plurality of elements installed on at least one of the room and the medical imaging system, the elements collectively creating a first theme that forms a physical environment at least partially surrounding a patient, wherein the theme is presented in a manner to reduce the level of patient anxiety and fear experienced by the patient being imaged. A medical imaging system is also described. A method of imaging a patient using the facility, a method of remodeling an existing facility, and a method of determining a theme to be used in a medical facility are also described.

Abstract: A method for the acquisition of measurement data of a breathing examination subject by magnetic resonance includes the following steps: (a) detect the physiological breathing signal of the examination subject with a breathing signal detection unit, (b) evaluate the detected breathing signal in an evaluation unit, (c) based on the evaluated breathing signal, calculate in a computer at least one parameter affecting the type of acquisition of measurement data by means of magnetic resonance, (d) detect a current physiological breathing signal with the breathing signal detection unit, (e) compare the last detected breathing signals with at least one trigger condition, (f) initiate the acquisition of measurement data using the calculated parameter from step (c) upon satisfaction of the trigger conditions from step (e), (g) repeat the steps (d) through (f) until all desired measurement data have been acquired, and (h) store and/or process the acquired measurement data in a memory and/or processing unit.

Abstract: A diagnostic imaging apparatus and method are provided. The diagnostic imaging apparatus includes a detection unit configured to detect a lesion from a medical image, an interpretation unit configured to acquire a shape feature value by interpreting a shape of the detected lesion in a frequency domain, and a diagnosis unit configured to determine whether the detected lesion is benign or malignant based on the acquired shape feature value.

Abstract: Medical examination or treatment device, in particular x-ray or CT device, comprising a control device controlling the operation of one or a number of device elements, as well as at least one mobile control element assigned to the control device, the control element communicating wirelessly with the control device for operating the examination or treatment device to issue control signals, with a detector element for detecting an item of information which can be read out or sent by a control element assigned to the control device during a movement of the control element from the room containing the medical examination or treatment device, the room communicating with the control device which disables the control operation as a function of the detection result.

Abstract: One or more techniques and/or systems described herein provide for generating a radiographic image and ultrasound image depicting parallel planes of an object under examination and may be used in conjunction with radiographic or ultrasound techniques known to those in the field (e.g., x-ray tomosynthesis, computed tomography ultrasound imaging, etc.). An ultrasound frontend component is configured to transmit ultrasound waves in a direction substantially parallel to a trajectory of radiation. In one example, one or more radiographic images of an object are spatially coincident to one or more ultrasound images of the object in the same position and/or geometric shape/volume, and the images may be combined to generate a combined image depicting features of the ultrasound image (e.g., the sensitivity of the ultrasound image) and features of the radiographic image (e.g., the morphological details of the radiographic image).

Abstract: An automatic atherectomy system uses a rotary burr at the tip of a catheter as a sensing device, in order to measure both electrical conductivity and permittivity of surrounding tissue at multiple frequencies. From these parameters it is determined which tissue lies in different directions around the tip. A servo system steers the catheter tip in the direction of the tissue to be removed. In non-atherectomy applications the rotary burr can be replaced with any desired tool and the system can be used to automatically steer the catheter to the desired position. The steering may be done hydraulically, by pressurizing miniature bellows located near the catheter tip.

Abstract: A method, including constructing a simulated surface of a body cavity, and pressing a distal end of a probe against a wall of the body cavity. While pressing the distal end against the wall, position measurements are accepted from the probe indicating a position of the probe within the body cavity, and force measurements are accepted from the probe indicating a force between the distal end and the wall. A distortion in the simulated surface is created at the position indicated by the position measurements, so as to form a distorted surface, upon detecting that the force measurements exceed a predefined amount. The distorted surface is then displayed.