Abstract: Device for carrying out and monitoring an atherectomy, with which a cutting knife driven in a rotating manner by an external unit and set back to project into an opening in the tip of the catheter can be pressed onto the artery wall by means of an inflatable balloon arranged on the side of the catheter casing opposite the window opening, an atherectomy catheter being connected to an OCT catheter to form an integrated unit.

Abstract: An integrated transducer device includes an optical transducer and an acoustic transducer integrally joined with the optical transducer. The acoustic transducer includes a membrane responsive to acoustic signals, the membrane being aligned with the optical transducer such that optical signals emitted or received by the optical transducer pass through the membrane. A propagation direction of the acoustic signals emitted or received by the acoustic transducer is collinear with a propagation direction of the optical signals emitted or received by the optical transducer.

Abstract: The invention relates to a method and device for performing coordinate transformation for navigation-guided procedures using an imaging diagnostic tool, especially an X-ray diagnostic tool, and a position-determining system. In the vicinity of the image receiver, the diagnostic tool has one or more three-dimensional reference structure that can be touched with a pointer of a position-determining system. From the known geometry of the three-dimensional reference structure and the coordinates of the touched points determined by the position-determining system, a coordinate transformation is created between the coordinate system of the diagnostic tool and the coordinate system of the position-determining system. Navigation for an instrument captured by the position-determining system can be performed in reconstructed images of the diagnostic tool after the registration procedure.

Abstract: In one aspect, the invention relates to a probe. The probe includes a sheath, a flexible, bi-directionally rotatable, optical subsystem positioned within the sheath, the optical subsystem comprising a transmission fiber, the optical subsystem capable of transmitting and collecting light of a predetermined range of wavelengths along a first beam having a predetermined beam size. The probe also includes an ultrasound subsystem, the ultrasound subsystem positioned within the sheath and adapted to propagate energy of a predetermined range of frequencies along a second beam having a second predetermined beam size, wherein a portion of the first and second beams overlap a region during a scan.

Abstract: An optical coherent tomographic image forming apparatus including a light guide configured to divide a light into a measurement light and a reference light; a flush unit configured to discharge a flush liquid into a body lumen; a refractive index setting unit configured to set a refractive index of the flush liquid; an adjustment value setting unit configured to set an adjustment value; a calibration unit for adjusting the length of the reference optical path or the length of the measurement optical path based on the adjustment value; an image construction unit configured to construct a cross-sectional image; and an offset value calculation unit for calculating an offset value of the length of the reference optical path based on a changed refractive index when the refractive index of the flush liquid is changed by the refractive index setting unit after calibration is executed by the calibration unit.

Abstract: Methods, and apparatuses are provided that include a first imaging element configured to generate a first observation of a first object, the first observation of the first object being generated at a first time, wherein the first object is associated with a volume of interest (VOI). The system further includes a second imaging element configured to generate a first observation of a second object, wherein the first observation of the second object is generated at a second time, and the second object is associated with the VOI. A first positioning of the VOI is determined based on the first observation of the first object and the first observation of the second object, a third time for the first imaging element is determined based on a positioning parameter associated with the first positioning of the VOI, and a second observation of the first object is generated at the third time.

Abstract: A volume of a patient can be mapped with a system operable to identify a plurality of locations and save a plurality of locations of a mapping instrument. The mapping instrument can include one or more electrodes that can sense a voltage that can be correlated to a three dimensional location of the electrode at the time of the sensing or measurement. Therefore, a map of a volume can be determined based upon the sensing of the plurality of points without the use of other imaging devices. An implantable medical device can then be navigated relative to the mapping data.

Abstract: An exemplary method includes use of a multielectrode device that can help position a cardiac stimulation lead to an optimal site in the heart based at least in part on cardiac motion information acquired via the multielectrode device and one or more pairs of current delivery electrodes that establish potential fields (e.g., for use as a coordinate system). An exemplary mutlielectrode device may be a multielectrode catheter or a multifilar, electrode-bearing guidewire. Various other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Deep Vein Thrombosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal peripheral veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's peripheral veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or symptoms associated with these maladies. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Multiple Sclerosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal jugular veins (IJV) or azygous veins (AZV). In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's IJV or AZV veins are provided.

Abstract: Diagnostic apparatus (20) includes an antenna 32, which is configured to direct radio frequency (RF) electromagnetic waves into a living body and to generate signals responsively to the waves that are scattered from within the body. Processing circuitry (36) is configured to process the signals so as to locate a feature in a blood vessel in the body.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Deep Vein Thrombosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal peripheral veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's peripheral veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal pulmonary veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's pulmonary veins are provided.

Abstract: Embodiments of the disclosure relate to medical devices and, in particular, to medical visualization systems and methods of use. In one embodiment, a medical visualization system may include a video source configured for insertion into a patient and an external data source. A central processing unit in communication with the video source and the external data source may be configured to merge data from the video source and data from the external data source into a left hybrid image and a right hybrid image. The medical visualization system may further include eyewear having left and right oculars in communication with the central processing unit. The left ocular and right ocular may each include a display, and the displays may be configured to project the left hybrid image on the left display and the right hybrid image on the right display.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal pulmonary veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's pulmonary veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal pulmonary veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's pulmonary veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Deep Vein Thrombosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal peripheral veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's peripheral veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Deep Vein Thrombosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal peripheral veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's peripheral veins are provided.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Multiple Sclerosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal jugular veins (IJV) or azygous veins (AZV). In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's IJV or AZV veins are provided.

Abstract: When delivering a therapy to a patient, such as a drug to a brain of a patient, an optimized delivery point can be selected. The optimized point can be based on physics, physiology, and pharmacology. The optimized point can be used for planning a surgical navigation procedure.

Abstract: An ultrasound medical treatment system includes an end effector insertable into a patient. The end effector includes a tissue-retaining device. The tissue-retaining device includes a first tissue-retaining member having an ultrasound medical-treatment transducer and includes a second tissue-retaining member. The first and second tissue-retaining members are operatively connected together to retain patient tissue between the first and second tissue-retaining members and to release patient tissue so retained. In one example, the second tissue-retaining member has an ultrasound reflector. In the same or a different example, the ultrasound medical-treatment transducer is an ultrasound imaging and medical-treatment transducer.

Abstract: There is described a system for carrying out and monitoring minimally-invasive interventions with an x-ray device, in which at least one x-ray emitter and a x-ray detector are attached to one or more robot arms of one or more multi-axis articulated-arm robots, with which they are able to be moved for recording images from different projection directions on a predeterminable path around a patient support facility. The system includes a control and evaluation unit with interfaces for catheters and devices for carrying out the minimally-invasive intervention. The control and evaluation unit is embodied for the processing of measurement and/or image data which it receives from the catheters and devices and for control of the catheters and devices for recording the measurement and/or image data. With the proposed system the workflow is covered completely and seamlessly from the examination to the therapy, especially in the treatment of tachycardial arrythmias.

Abstract: An apparatus for diagnosing a patient includes a catheter having a tip. The apparatus includes a bioptome disposed in proximity to the tip to obtain a tissue sample of the patient. The apparatus includes a radiodetector disposed in proximity to the tip to detect radiation in the patient. A method for diagnosing a patient includes the steps of moving a tip of a catheter to a desired location in a blood vessel of the patient determined by radiation detected by a radiodetector disposed in proximity to the tip. There is the step of obtaining a tissue sample of the patient with a bioptome disposed in proximity to the tip.

Abstract: A surgical instrument for treating tissue during use of a diagnostic scanning device. The surgical instrument includes a housing, an actuating mechanism and an end effector assembly. The actuating mechanism is configured to activate the end effector assembly to treat tissue. At least a portion of the end effector is made of a material that is compatible with the diagnostic scanning device and allows a user to insert and activate the end effector to treat tissue at a surgical site within a patient while the surgical site is monitored during diagnostic scanning device.

Abstract: Systems and methods are provided for timing of a plurality of imaging observation elements based on a volume of interest (VOI). One system includes a first imaging element configured to generate a first observation of a first object, wherein the first observation is generated at a first time, and the first object is associated with a volume of interest (VOI). A second imaging element is configured to generate a first observation of a second object, the first observation of the second object generated at a second time, wherein the second object is associated with the VOI. The system is configured to determine a first positioning of the VOI based on the first observation of the first object and the first observation of the second object, determine a plurality of imaging times for the first imaging element to generate a plurality of additional observations of the first object.

Abstract: A computer assisted surgery system is described for assisting a surgeon in aligning a drill with the interlocking holes of an implanted intramedullary (IM) rod used for fixation of long bone fractures. With the IM rod inserted, a localizing device measures the pose of a tracked adapter attached to the rod's exposed end. Approximate AP and lateral fluoroscopic x-ray images are acquired of the end of the rod with the interlocking holes. Image processing algorithms determine the actual position of the rod and calculate an adjustment to the pose of the tracked adapter and IM rod. Using the adjusted pose information, the system displays, in three roughly orthogonal views, a representation of the drill trajectory relative to the images of the IM rod and relative to a graphic representation of the IM rod.

Abstract: In a medical apparatus and method, the apparatus installation has a placement device for a patient, into which placement device is integrated at least one electromechanical sensor. A signal evaluation device is supplied with the measurement signals generated with the at least one electromechanical sensor, for evaluation. The medical apparatus is connected with the signal evaluation device, and the medical apparatus acquires measurement signals that relate to breathing and/or cardiac activity of the patient with the at least one electromechanical sensor upon support of the patient on said placement device. Trigger signals are generated with the signal evaluation device based on the measurement signals which relate to breathing cycle and/or cardiac cycle of the patient. The operation of the medical apparatus is controlled based on the trigger signals.

Abstract: In a method to control a medical apparatus of an installation having: a contact device for a patient, at least one electrical potential sensor that can be coupled to the body of said patient is integrated into the contact device. A signal evaluation device is provided with measurement signals generated with the electrical potential sensor for evaluation. The medical apparatus is connected with the signal evaluation device, and measurement signals that relate to the breathing and/or cardiac activity of the patient are acquired with the at least one electrical potential sensor coupled to the body of said patient upon contact of the patient with the contact device. Trigger signals are generated with the signal evaluation device based on the measurement signals that relate to the breathing cycle and/or the cardiac cycle of the patient. Operation of the medical apparatus is controlled based on the trigger signals.

Abstract: In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.

Abstract: A method of treating a disorder may include positioning a thermoelectric device in the ear canal of a subject and activating the thermoelectric device to deliver caloric vestibular stimulation and/or cranial nerve stimulation effective to treat the disorder. In some embodiments, the ear canal may be cooled sufficiently to treat the disorder. In alternative embodiments, the ear canal may be warmed sufficiently to treat the disorder.

Abstract: A system and method for specificity-based multimodality three-dimensional optical tomography imaging comprises steps of: optical imaging to obtain a light intensity of body surface optical signal of an imaging target; CT imaging to obtain structure volume data; establishing an equation representing a linear relationship between the distribution of the obtained light intensity of body surface optical signal of the imaging target, the obtained CT discrete mesh data and the distribution of unknown internal self-luminescence light sources; establishing a dynamic sparse regularization target function in every iteration for the equation; and reconstructing a tomography image. The present invention well considers the optical specificity of tissue, in which there is a non-uniform optical characteristic parameter distribution within the same tissue when finite element modeling is used, which is closer to the real situation, so that an accurate imaging effect is achieved.

Abstract: A system for video based registration between images during a skeletal medical procedure includes a stereoscopic camera, a two dimensional image detector and a registration processor. The camera is associated with a stereoscopic coordinate system, the camera acquires a stereoscopic image pair of fiducial marks fixed onto a skeletal structure. Fiducial representations of the fiducial marks appear on the stereoscopic image pair, and a skeletal representation of the skeletal structure appears on two different 2D images. The registration processor registers a stereoscopic coordinate system with a 3D coordinate system associated with a volumetric image detector, and superimposes 3D information on at least one volumetric image. The registration processor registers the stereoscopic coordinate system with the 3D coordinate system by registering the stereoscopic coordinate system with the 2D coordinate system and by registering the 2D coordinate system with the 3D coordinate system.

Abstract: A method for assisting a person performing a minimally invasive intervention with a catheter involving a puncture of a septum, in particular of a heart, is proposed. A three-dimensional image data record is recorded showing an anatomical structure in the region of the septum. An item of septum information showing the position of the septum is determined in the image data record and additional information is derived from the position of the anatomical structure influencing or showing the selection of a puncture site. During the intervention, the fluoroscopic images of the region are continuously recorded and a current fluoroscopic image is displayed and superimposed with the septum information and/or the additional information based on a registration of the image data record with the fluoroscopic images.

Abstract: Conjugates of porphyrin, chlorophyll and bacteriochlorophyll photosensitizers with RGD-containing peptides or RGD peptidomimetics are provided that are useful for photodynamic therapy (PDT), particularly vascular-targeted PDT (VTP), of tumors and nonneoplastic vascular diseases such as age-related macular degeneration, and for diagnosis of tumors by different techniques.

Abstract: MRI-Surgical systems include: (a) at least one MRI-compatible surgical tool; (b) a circuit adapted to communicate with an MRI scanner; and (c) at least one display in communication with the circuit. The circuit electronically recognizes predefined physical characteristics of the at least one tool to automatically segment MR image data provided by the MRI scanner whereby the at least one tool constitutes a point of interface with the system. The circuit is configured to provide a User Interface that defines workflow progression for an MRI-guided surgical procedure and allows a user to select steps in the workflow, and wherein the circuit is configured to generate multi-dimensional visualizations using the predefined data of the at least one tool and data from MRI images of the patient in substantially real time during the surgical procedure.

Abstract: Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.

Abstract: A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.

Abstract: The invention relates generally to biopsy needle guidance which employs an x-ray/gamma image spatial co-registration methodology. A gamma camera is configured to mount on a biopsy needle gun platform to obtain a gamma image. More particular, the spatially co-registered x-ray and physiological images may be employed for needle guidance during biopsy. Moreover, functional images may be obtained from a gamma camera at various angles relative to a target site. Further, the invention also generally relates to a breast lesion localization method using opposed gamma camera images or dual opposed images. This dual head methodology may be used to compare the lesion signal in two opposed detector images and to calculate the Z coordinate (distance from one or both of the detectors) of the lesion.

Abstract: A system for visualizing needle entry into a body is presented. The system includes a needle for entering a body. The needle is coated with a radiation scattering coating on at least a portion of the needle. The system additionally includes a radiation visualization device which detects reflected radiation directed at a target body and enables medical personnel to view anatomical structures such as a blood vessel along with the inserted needle within a body.

Abstract: Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be effected under gonioscopic control. Internal delivery may he controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

Abstract: A system and method for navigating a medical instrument in a branched structure of a body employs a tracking system, for collecting positional information for the medical instrument, and data, which defines a geometrical model of the branched structure, in particular, coordinates for predetermined points defining a pathway extending along branches of the model. Coordinates are identified for each Euclidean distance of the instrument, from an anchor point of a coordinate system for the tracking system, that corresponds to a Euclidean distance of a designated point, of the predetermined points, from a reference point of a coordinate system for the model, wherein the anchor point of the tracking coordinate system has been established to correspond to the reference point of the model coordinate system. The two coordinate systems are registered to one another via a mathematical transformation using the identified coordinates of the instrument and the corresponding coordinates of each designated point.

Abstract: A method for assisting optimum positioning of an occlusion site in a blood vessel in a tumor embolization is provided. Tumors are cut off from the blood supply by the embolization which is an artificial occlusion of blood vessels. The vessels around the tumor and at the same time the planned site for occlusion are firstly determined. A path from the access to the vessels can be determined based on image recognition, and with the aid of this path the site for occlusion can then be optimally determined. A computer system assists the doctor carrying out the treatment by a suitable display.

Abstract: Methods are disclosed for assessing the condition of a cartilage in a joint, particularly in a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the effect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy. Planning therapy may include generating one or more physical models.

Abstract: An X-ray moving image radiographing apparatus includes an X-ray detector configured to detect an X-ray transmitting through a subject to acquire a subject image, an image processing unit configured to process an X-ray radiographic image output from the X-ray detector, and a control unit configured to capture a mask image by selectively scanning X-ray focal positions of an X-ray source which has a plurality of X-ray focal points so that an X-ray incident angle varies with respect to a target point of the subject, and to capture a moving image after a predetermined work is performed on the subject by selectively scanning X-ray focal positions of the X-ray source similar to the scanning operation used to capture the mask image.

Abstract: A device for delivering fluid inside a vessel includes an elongated member having a proximal end, a distal end, and a channel extending between the proximal end and the distal end, and a first port located at the distal end, wherein the first port is in fluid communication with the channel, wherein the first port faces at least partially towards a proximal direction.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.

Abstract: A three-dimensional positioning device for minimally invasive surgery includes a base, two angle adjustable assemblies, an arc, a sliding assembly, a first positioning assembly, a second positioning assembly and a third positioning assembly. The base includes two first frames and two second frames. Two ends of each second frame are connected to the first frames respectively. Each first frame has a pivotal member. The angle adjustable assemblies are pivotably connected to the pivotal member of the first frame respectively. The arc includes a hollow track member. The angle adjustable assemblies are connected to two ends of the arc. The sliding assembly is mounted on the track member of the arc according to a predetermined position of a nidus. Therefore, the three-dimensional positioning device can effectively improve precision and operation more precisely in minimally invasive surgery to increase surgery success rate.

Abstract: Example embodiments are directed to a method of correcting attenuation in a magnetic resonance (MR) scanner and a positron emission tomography (PET) unit. The method includes acquiring PET sinogram data of an object within a field of view of the PET unit. The method further includes producing an attenuation map based on a maximum likelihood expectation maximization (MLEM) of a parameterized model instance and the PET sinogram data.

Abstract: An imaging system, including (1) a CT scanner configured to scan an object arranged on a patient pallet; (2) a PET scanner, including a first detector portion, including first detector elements, arranged circumferentially around the patient pallet, the first detector portion having a predetermined axial extent and transaxially subtending less than 360 degrees with respect to a central axis of the scanner; and a second detector portion, including second detector elements, arranged separately from and opposing the first detector portion, wherein the second detector elements are of a different type than the first detector elements, and the second detector portion is configured to be movable radially and circumferentially around the object; and (3) an acquisition subsystem configured to acquire first event data from the first detector portion and to acquire second event data from the second detector portion.