Abstract: A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.

Abstract: The present invention is directed to a system and method in which real-time ubiquitous imaging is feasible in local areas, such as inside a clinic, hospital room or doctor office. This is achieved by designing a wireless network having a central processing server with, for example, distributed broadband acquisition and video bus capability. Remote access is possible using store-and-forward image transfer over a wide area network. With these capabilities, a physician can use a handheld transducer (such as an ultrasound transducer) as a basic tool to facilitate diagnostic decisions similar to the way a stethoscope is used today.

Abstract: A data processing method for the ultrasonic diagnostic apparatus, according to the present invention includes: acquiring data corresponding to the same predetermined depth, out of a plurality of pieces of ultrasonic data acquired by performing the plurality of times of ultrasonic transmitting/receiving operations in the same sound ray direction and at predetermined time intervals; filtering the acquired data corresponding to the same predetermined depth, and extracting echo data from a moving part in a body; acquiring the first autocorrelation amplitude value when this echo data is delayed by a first predetermined time period; acquiring the second autocorrelation amplitude value when the above-described echo data is delayed by a second predetermined time period; and further relating the multiplied value obtained by multiplying the first autocorrelation amplitude value by the second autocorrelation amplitude value, to the luminance of a predetermined hue.

Abstract: Provided herein are composite passive layers for ultrasound transducers having acoustic properties that can be easily tailored to the needs of the transducer application using current microfabrication techniques. In an embodiment, a passive layer comprises metal posts embedded in a polymer matrix or other material. The acoustic properties of the passive layer depend on the metal/polymer volume fraction of the passive layer, which can be easily controlled using current microfabrication techniques, e.g., integrated circuit (IC) fabrication techniques. Further, the embedded metal posts provide electrical conduction through the passive layer allowing electrical connections to be made to an active element, e.g., piezoelectric element, of the transducer through the passive layer. Because the embedded metal posts conduct along one line of direction, they can be used to provide separate electrical connections to different active elements in a transducer array through the passive layer.

Abstract: In an ultrasound diagnosis apparatus, a plurality of sub arrays are defined on a 2D array transducer. A plurality of groups are defined for each sub array. Each group is basically composed of a plurality of transducer elements which are connected in parallel with each other. A sub array shape is variably defined for a plurality of sub arrays in accordance with the beam direction and the depth of a focal point. Further, a grouping pattern is variably defined for each sub array. The acoustic distances between the respective transducer elements and the focal point is made as equal as possible for a plurality of transducer elements forming each group, whereby a preferable beam profile can be obtained.

Abstract: Systems and methods for grading signals from microemboli in blood flow monitored using a Doppler ultrasound system. Signals from microemboli in blood flow are graded by calculating a value related to a power for the signals from microemboli in blood flow and categorizing the signals into one of at least two grades based on the calculated value. Alternatively, signals can be categorized by assessing a power value for the microemboli in blood flow during a period of monitoring. In response to the power value being greater than or equal to a threshold value, the microemboli in blood flow are categorized based on the power value, and in response to the power value being less than the threshold value, a number of microemboli are counted during at least a portion of the period of monitoring and the microemboli are categorized based on the number.

Abstract: A Doppler radar signal processing system and method and a Doppler radar employing the system or the method. In one embodiment, the system includes: (1) an input configured to receive at least one radar output signal representing a reflected Doppler radar signal, (2) signal processing circuitry coupled to the input and configured to produce an arc-length cardiopulmonary signal from the at least one radar output signal and employ a respiration fundamental frequency estimate to extract a heart rate signal from the arc-length cardiopulmonary signal and (3) an output coupled to the signal processing circuitry and configured to provide the heart rate signal.

Abstract: Unipolar, bipolar or sinusoidal transmitters may leave the transmitter in any of various states at the end of one pulse. Undesired acoustic energy may be generated to change states prior to beginning another transmit sequence or pulse. For example, phase inversion for tissue harmonic imaging is performed where two sequential pulses are transmitted with different phases. The first waveform starts at a low state and ends at the low state of a unipolar transmitter. The next waveform starts at the high state. Transmit apodization or spectrum control techniques may require a pattern of waveform starting states different than a current state. Acoustic disruption due to a change of state of the transmitter between transmissions for imaging is minimized.

Abstract: An ultrasonic transducer in which lead wire connection is facilitated even when piezoelectric devices are divided in order to prevent lateral vibrations from affecting longitudinal vibrations is manufactured by a method comprising: a step in which first dicing grooves are formed on an acoustic matching layer and a piezoelectric device plate that are mounted together in order to form a plurality of piezoelectric devices; a step in which a board and the respective piezoelectric devices are connected together; a step in which surfaces in the vicinity of locations at which the board and the piezoelectric devices are connected together are coated with a conductive sheet; and a step in which the plurality of transducer elements are formed by forming second dicing grooves between the first dicing grooves formed on the piezoelectric devices and the board that is coated with the conductive sheet and on the acoustic matching layer.

Abstract: The present invention aims to provide a delay device having an analog delay line adaptable to a plurality of frequencies with a less number of taps. The analog delay line has a maximum delay amount equivalent to a wavelength from over a ? wavelength of a predetermined maximum wavelength of an input signal to under a 1 wavelength thereof. Tap intervals up to a delay point equivalent to ½ of a predetermined minimum wavelength of the input signal are different from tap intervals placed ahead of those. The maximum wavelength is a wavelength of a signal having a frequency of 2 MHz, for example, and the minimum wavelength is a wavelength of a signal having a frequency of 5 MHz, for example.

Abstract: An ultrasound scanner is equipped with one or more fuzzy control units that can perform adaptive system parameter optimization anywhere in the system. In one embodiment, an ultrasound system comprises a plurality of ultrasound image generating subsystems configured to generate an ultrasound image, the plurality of ultrasound image generating subsystems including a transmitter subsystem, a receiver subsystem, and an image processing subsystem; and a fuzzy logic controller communicatively coupled with at least one of the plurality of ultrasound imaging generating subsystems.

Abstract: A method and apparatus for extracting an envelope curve of a spectrogram, for use in measurement of blood flow velocity by using spectral Doppler techniques, the method comprising steps of: processing RF ultrasound echo signals to obtain Doppler signals; performing spectral analysis on the Doppler signals, to obtain a corresponding power spectrum P(f); estimating a forward maximum frequency fmax+ and a backward maximum frequency fmax? for the Doppler signals at a predetermined moment, according to the power spectrum P(f) of the Doppler signals at the predetermined moment; determining a noise frequency range according to the two maximum frequencies, so as to estimate an average noise power E; and correcting the forward maximum frequency and the backward maximum frequency by using the average noise power E. With the method of the invention, influence from the SNR and bandwidth on the envelope curve may be reduced, so as to be useful for accurate computation of blood flow parameters.

Abstract: An enhanced intraluminal flow measurement system and method is conducive for a low-power ultrasonic system that can use continuous-wave (CW) Doppler sensing and wireless RF telemetry. Applications include measurement of blood flow in situ in living organisms. Implementations include an extraluminal component located outside of a body, such as a human or animal body, containing a lumen. The extraluminal component can be wirelessly coupled via an RF magnetic field or other RF field to an implantable intraluminal component. The intraluminal component (i.e. implant) is implanted inside of the lumen of the body such as a heart or elsewhere in a vasculature (such as in a dialysis shunt). The intraluminal component can telemeter, via RF electromagnetic signals, flow data directly out of the body housing the intraluminal component to be received by the extraluminal component.

Abstract: An enhanced intraluminal flow measurement system and method is conducive for a low-power ultrasonic system that can use continuous-wave (CW) Doppler sensing and wireless RF telemetry. Applications include measurement of blood flow in situ in living organisms. Implementations include an extraluminal component located outside of a body, such as a human or animal body, containing a lumen. The extraluminal component can be wirelessly coupled via an RF magnetic field or other RF field to an implantable intraluminal component. The intraluminal component (i.e. implant) is implanted inside of the lumen of the body such as a heart or elsewhere in a vasculature (such as in a dialysis shunt). The intraluminal component can telemeter, via RF electromagnetic signals, flow data directly out of the body housing the intraluminal component to be received by the extraluminal component.

Abstract: An enhanced intraluminal flow measurement system and method is conducive for a low-power ultrasonic system that can use continuous-wave (CW) Doppler sensing and wireless RF telemetry. Applications include measurement of blood flow in situ in living organisms. Implementations include an extraluminal component located outside of a body, such as a human or animal body, containing a lumen. The extraluminal component can be wirelessly coupled via an RF magnetic field or other RF field to an implantable intraluminal component. The intraluminal component (i.e. implant) is implanted inside of the lumen of the body such as a heart or elsewhere in a vasculature (such as in a dialysis shunt). The intraluminal component can telemeter, via RF electromagnetic signals, flow data directly out of the body housing the intraluminal component to be received by the extraluminal component.

Abstract: The invention relates to systems and methods for assessing blood flow in single or multiple vessels and segments, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for effect, for assessing risk factors, for evaluating intracranial pressure and for analyzing the results in a defined manner. The invention enables direct monitoring of therapies, substances and devices on blood vessels, especially those of the cerebral vasculature. Relevant blood flow parameters include mean flow velocity, systolic acceleration, and pulsatility index. Measurement and analysis of these parameters, and others, provides details regarding the vascular health of individual and multiple vessels and a global analysis of an individual's overall vascular health. The invention is applicable as both a system and method for monitoring and improving the design, performance, marketing and use of vascular stents.

Abstract: An ultrasonic probe includes piezoelectric elements each including grooves parallel to each other and arrayed in a direction substantially parallel to the grooves, and a mixed member which is to fill the grooves and obtained by mixing in a nonconductive resin member a nonconductive granular substance with a coefficient of thermal expansion of not more than substantially 10?5 K?1.

Abstract: A method of measuring blood flow including several steps. In an initial step a first ultrasound beam is oriented in a direction substantially perpendicular to the direction of the blood flow to be measured. Next, the Doppler spectrum obtained from the backscattered echoes of said first ultrasound beam is measured. Subsequently, the ultrasound beam is reoriented so that the Doppler spectrum of the backscattered echoes of the ultrasound beam is substantially symmetrical around the zero frequency. The Doppler frequency of the backscattered echoes of a second ultrasound beam oriented at a fixed angle to the first ultrasound beam is then measured. Finally, the rate of blood flow is calculated based on the angle between the ultrasound beams and the measured Doppler frequency of the backscattered echoes of the second ultrasound beam.

Abstract: In a method and apparatus for fully automatic detection of anomalies in vessel structures, a 3D volume data set of an imaging 3D measurement of the vessel structure is obtained and, for an evaluation device, the vessel structure is detected in the 3D volume data set and subsequently is skeletonized in order to obtain a three-dimensional course of skeletonization paths. Characteristic quantities of the vessel structure are automatically determined along the skeletonization paths as features that are significant for an anomaly to be detected, in order obtain one or more feature series. The determined feature series are classified by non-linear imaging and comparison with reference feature series that have been determined for different classes of known vessel structures that contain different anomalies and known vessel structures without anomalies. Anomalies corresponding to the classification thus are identified.

Abstract: A portable apparatus for conveying blood flow parameters to a user, the apparatus comprising: a transducer device for providing for Doppler monitoring of flows within a patient; a processing unit interconnected to the transducer unit and adapted to extract a blood flow signal from the operation of the transducer and process the blood flow signal so as to produce a video blood flow signal and an audio blood flow signal; a display unit interconnect to the processing unit for visualising the video blood flow signal; and at least one audio emission devices interconnected to the processing unit for emission of the audio blood flow signal to the ears of the user.

Abstract: An ultrasonic low-noise analog beamformer for Doppler acquisition achieves high sensitivity by translating the frequency of the ultrasound echoes to an intermediate frequency, which is well above of the 1/f corner. This is accomplished by beamforming the downconverted RF signals instead of using their baseband representation. The baseband conversion, succeeding the beamformation, also incorporates the steps of clutter filtering and anti-aliasing. The invention is particularly suitable for low-voltage process technologies that support broadband applications.

Abstract: Ultrasound information for B-mode and CW Doppler mode use the same digital beamformer. Due to sigma-delta conversion or over sampling, sufficient dynamic range is provided for the desired bandwidth. By mixing the input ultrasound information to base band before conversion, additional dynamic range may be provided. The electrical impedance may be better matched to elements by connecting a different number of sigma-delta converters to an element. Elements with lower impedance may be connected to a plurality of sigma-delta converters. To increase the aperture size for elements with a higher impedance, the same sigma-delta converters may be used as separate receive beamformer channels without the summation.

Abstract: An ultrasound system is provided comprising an ultrasound probe having a 2D matrix of transducer elements transmitting a continuous wave (CW) Doppler transmit signal into an object of interest. The CW transmit signal includes a dither signal component and the probe receives ultrasound echo signals from the object in response to the CW transmit signal. The probe generates an analog CW receive signal based on the ultrasound echo signals. An analog to digital (A/D) converter converts the analog CW receive signal to a digital CW receive signal at a predetermined sampling frequency and a processor processes the digital CW receive signal in connection with CW Doppler imaging.

Abstract: The present invention relates to a continuous wave Doppler beam former application specific integrated circuit (CW-ASIC). The beam former may be a transmit or receive beam former.

Abstract: A plurality of 2D sub arrays are defined on a 2D array transducer for effecting transmission and reception of ultrasound. For each sub array, a plurality of groups are set. More specifically, a plurality of (16, for example) transducer elements forming a sub array are grouped or divided into a plurality of (4, for example) groups. A multiplexer sums a plurality of receiving signals output from the plurality of transducer elements for each group, and generates a group receiving signal. A plurality of group receiving signals thus generated are then subjected to a sub phase adjusting and summing process to form a sub phase adjusted and summed signal. A plurality of sub phase adjusted and summed signals corresponding to the plurality of sub arrays are then subjected to a main phase adjusting and summing process. A sub phase adjusting and summing processing section is provided within a probe head, a cable connector, or an apparatus body.

Abstract: The present invention relates to a continuous wave Doppler beam former application specific integrated circuit (CW-ASIC). The beam former may be a transmit or receive beam former.

Abstract: An apparatus and method for detecting the highest velocity of fluid flow with in a volume having multiple sources of fluid flow with different velocities. There are multiple pairs of receiving transducers arranged about a region wherein each transducer in a pair is positioned on the same axis with respect to the region. A transmitting transducer is positioned at the region to provide an output frequency signal, which frequency signal is transmitted to the fluid flow area volume. This causes Doppler shifted frequency signals to be reflected, with the Doppler shift being a function of the fluid flow velocity. Each of the receiving transducers receive the Doppler shifted signals. Signal processing means are responsive to the Doppler shifted signals and the original transmitted output frequency signal to process those signals to provide a velocity signal for each pair of transducers. One then selects the maximum velocity signal obtained from the pair.

Abstract: The present invention relates generally to systems and methods for assessing blood flow in blood vessels, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for adverse effects, and for assessing the effects of risk factors, therapies and substances, including therapeutic substances, on blood vessels, especially cerebral blood vessels, all achieved by measuring various parameters of blood flow in one or more vessels and analyzing the results in a defined manner. The relevant parameters of blood flow include mean flow velocity, systolic acceleration, and pulsatility index. By measuring and analyzing these parameters, one can ascertain the vascular health of a particular vessel, multiple vessels and an individual. Such measurements can also determine whether a substance has an effect, either deleterious or advantageous, on vascular health. The present invention further provides an expert system for achieving the above.

Abstract: A system and method for screening tissue is provided. The system provides a computer-based system for distinguishing between normal and potentially abnormal tissue. The system includes computer components for generating and receiving ultrasonic waves, for storing a tissue model, and for analyzing received ultrasonic waves in the context of the tissue model.

Abstract: An ultrasonic imaging technique and apparatus with a portable scanning head. In one form of the scanning head, a reflective scanner is provided with a variable focus, and in another form the scanning head has several reflective facts of respectively different focal lengths.

Abstract: The present invention relates generally to systems and methods for assessing blood flow in blood vessels, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for adverse effects, and for assessing the effects of risk factors, therapies and substances, including therapeutic substances, on blood vessels, especially cerebral blood vessels, all achieved by measuring various parameters of blood flow in one or more vessels and analyzing the results in a defined manner. The relevant parameters of blood flow include mean flow velocity, systolic acceleration, and pulsatility index. By measuring and analyzing these parameters, one can ascertain the vascular health of a particular vessel, multiple vessels and an individual. Such measurements can also determine whether a substance has an effect, either deleterious or advantageous, on vascular health. The present invention further provides an expert system for achieving the above.

Abstract: The present invention relates generally to systems and methods for assessing blood flow in blood vessels, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for adverse effects, and for assessing the effects of risk factors, therapies and substances, including therapeutic substances, on blood vessels, especially cerebral blood vessels, all achieved by measuring various parameters of blood flow in one or more vessels and analyzing the results in a defined matter. The relevant parameters of blood flow include mean flow velocity, systolic acceleration, and pulsatility index. By measuring and analyzing these parameters, one can ascertain the vascular health of a particular vessel, multiple vessels and an individual. Such measurements can also determine whether a substance has an effect, either deleterious or advantageous, on vascular health. The present invention further provides an expert system for achieving the above.

Abstract: A continuous wave Doppler beam former comprises an application specific integrated circuit (CW-ASIC). The beam former may be a transmit or receive beam former and forming a medical ultrasound system comprising a plurality of channels forming a CW analog receive path.

Abstract: The present invention relates to a continuous wave Doppler beam former application specific integrated circuit (CW-ASIC). The beam former may be a transmit or receive beam former.

Abstract: An ultrasound system that performs image processing in the digital domain, including CW Doppler. The ultrasound system is provided with a transducer having a plurality of elements and an ultrasound receiver with a plurality of channels. Each channel receives an analog echo signal and outputs a digital representation of the analog echo signal using an A/D converter capable of converting a signal with a dynamic range of at least 154 dB.

Abstract: By bonding a conductive first matching layer 14 to the acoustic radiation surface side, which is the bottom side, of a belt-shape piezoelectric element on both faces with electrodes provided, and using a dicing machine to form divided grooves 16, an array of piezoelectric elements 6, 6, . . . , 6 is formed in the element array direction. By deepening the divided grooves 16, generation of cross talk can be prevented, and by filling the portions of the divided grooves 16 not in contact with the piezoelectric elements 6 with a conductive adhesive 17, a reduction in strength due to formation of the divided grooves 16 can be prevented, and a common connection between the ground electrode 13b on the bottom surface of each piezoelectric element 6 and the conductive first matching layer 14 can be reliably secured.

Abstract: A system for automatic manipulation of a transcranial Doppler probe device designed for placement on a patient's head comprising a bi-temporal probe hanger, a cylindrical probe housing having an inner electrical wiring, an ultrasound transducer with cable affixed on the probe cylindrical base having a coil, said probe cylindrical base placed within the cylindrical probe housing, a spring system affixed to provide perpendicular pressure on the probe cylindrical base, a system of roller balls, a locking system to affix the cylindrical probe housing to the frame of the bi-temporal probe hanger, a system software program and microprocessor for controlling the probe position, and a removable handle attached to the said probe cylindrical base. The system software ‘learns’ probe angulations after initial manual manipulations and then performs cerebral vessel insonation using electromotive force independent of operator.

Abstract: A Doppler receiver has a wide dynamic range and operates in a differential mode.

Abstract: In order to arrange continuous wave signal paths using fewer switches, a plurality of amplifying circuits 602 for respectively amplifying a plurality of continuous wave input signals, and outputting each respective pair of amplified signals that have mutually opposite phases for each continuous wave input signal; a plurality of selecting circuits 604, each of which selects one signal of the pair of amplified signals from each of the plurality of amplifying circuits; and a matrix switch 608 employing the output signals from the plurality of selecting circuits as input signals are provided.

Abstract: An apparatus for determining the velocity of a fluid flowing through a lumen comprises a first diffraction grating transducer (DGT) responsive to a continuous wave (CW) input and operable in a first mode for producing a first signal beam at a first frequency and first phase, and in a second mode for producing a second signal beam at the first frequency and a second phase; a second diffraction grating transducer (DGT) operating as a receiver and coupled to the first diffraction grating transducer at a predetermined angle, the second diffraction grating transducer producing a first beam which intersects the first DGT first beam for receiving a first reflected signal associated with the first signal beam, and for producing a second beam which intersects the first DGT second beam for receiving a second reflected signal associated with the second signal beam; the first beams adapted to intersect in a first predetermined region through which dynamic particles are undergoing velocity analysis, and the second beams a

Abstract: A strobed blood flow meter provides periodic measurements of blood flow velocity or volumetric blood flow over a cardiac cycle at reduced average power consumption, which is advantageous for reducing battery size, and extending device battery life, such as in an implantable application. Continuous wave Doppler, pulsed Doppler, laser Doppler, transit time, electromagnetic flow, and thermal dilution techniques are included. Strobing provides higher level excitation during active periods, which improves signal-to-noise ratio, and provides a low power standby mode during an idle time between active periods. The invention may be used for chronic or acute applications. Doppler or other signals may be telemetered from an implanted portion of the flow meter for further signal processing to extract velocity or volumetric flow. Alternatively, such signal processing is also implanted, such that the velocity signal can be telemetered to an remote monitor.

Abstract: A method and an apparatus for increasing the spatial resolution and sensitivity of a color flow image while maintaining a desired acoustic frame rate. The ultrasound energy is concentrated at a more narrowly defined focal region, which allows for increased flow sensitivity and vessel filling. Better flow uniformity across the color region of interest is also achieved. The method uses multiple transmit focal zones, and transmit and receive apertures having low f-numbers. Using multiple focal zones with low f-numbers allows for tight focusing over a larger depth-of-field. Unique waveforms and unique gain curves are used for each focal zone. Each focal zone is fired on a separate acoustic frame. An adaptive frame averaging algorithm is used to blend together the in-focus data from each of these acoustic frames before the data is displayed.

Abstract: An ultrasonic continuous wave doppler blood flow-meter deflects an ultrasonic continuous wave to an arbitrary angle and transmits it into an organism, thereby measuring a blood flow speed of the organism. Two continuous sine wave signals of different phases and a plurality of sets of pairs of coefficients are generated. One of each of the pairs of coefficients is multiplied to one of the two sine wave signals. The other one of each of the pairs of coefficients is multiplied to the other one of the two sine wave coefficients. After that, two sine wave signals after the multiplication are added, so that a plurality of synthesis sine wave signals are generated. When a plurality of micro vibrators are driven by the plurality of synthesis sine wave signals, the ultrasonic continuous wave is deflected to an arbitrary angle and is transmitted into the organism.