Contrast Enhancement Patents (Class 600/458)
  • Patent number: 11344204
    Abstract: A photoacoustic measurement probe and a probe unit capable of preventing generation of artifacts in a photoacoustic measurement apparatus are obtained. In a photoacoustic measurement probe having a light emitting unit that emits measurement light toward a subject, an acoustic wave detection element that detects an acoustic wave emitted from a portion of the subject that has received the measurement light, and a housing which has a surface facing the subject at the time of use and in which the light emitting unit and the acoustic wave detection element are housed, at least one slit that is opened to the housing surface and that extends from the housing surface toward the inside of the housing is provided between the light emitting unit and the acoustic wave detection element.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: May 31, 2022
    Assignee: FUJIFILM Corporation
    Inventors: Atsushi Osawa, Atsushi Hashimoto, Kaku Irisawa
  • Patent number: 11291866
    Abstract: Various approaches to generating and maintaining an ultrasound focus at a target region include configuring a controller to cause transmission of treatment ultrasound pulses from a transducer having multiple transducer elements; cause the transducer to transmit focusing ultrasound pulses to the target region and generate an acoustic reflector therein; measure reflections of the focusing ultrasound pulses from the acoustic reflector; based at least in part on the measured reflections, adjust a parameter value associated with one or more transducer elements so as to maintain and/or improve the ultrasound focus at the target region.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: April 5, 2022
    Assignee: INSIGHTEC, LTD.
    Inventors: Yoav Levy, Eyal Zadicario, Shuki Vitek, Javier Grinfeld, Ohad Silbiger
  • Patent number: 11207053
    Abstract: The present disclosure generally relates to using high frequency ultrasound to assess blood volume changes in a subject. A baseline blood volume value can be determined based on a weight of a subject or based on an initial/previous assessment test value. An image taken with the high frequency ultrasound can be retrieved. A test blood volume value can be measured in a field of view of the image. For example, the test blood volume can be determined based on a destruction/replenishment of a contrast agent during imaging by the high frequency ultrasound. A change in blood volume in the subject can be estimated by comparing the test blood volume value to the baseline blood volume value. The estimate of the change in blood volume can be used to assess a condition of the subject.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: December 28, 2021
    Assignee: UNIVERSITY OF HAWAII
    Inventor: Chad Walton
  • Patent number: 11166699
    Abstract: For estimating attenuation, diffraction effects are corrected by transmitting at different frequencies using apertures sized to match the on-axis intensity profile and/or resolution cell size between the transmissions where there is no attenuation. Attenuation causes a variance in return. A rate of change is estimated from a ratio of the magnitude of the signals or displacements responsive to the transmissions. The attenuation is calculated from the rate of change over depth of the ratio.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: November 9, 2021
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Yassin Labyed, Kutay F. Ustuner
  • Patent number: 11064973
    Abstract: An ultrasound probe according to an embodiment includes: transducer elements, phase reversal processing circuitry, and delay processing circuitry. The transducer elements, each of which is configured to generate a first echo signal by receiving a reflected wave of a first ultrasound wave and to generate a second echo signal by receiving a reflected wave of a second ultrasound wave corresponding to an ultrasound wave obtained by reversing the phase of the first ultrasound wave. The phase reversal processing circuitry is configured to reverse the phase of the second echo signal. The delay processing circuitry is configured to delay the first echo signal and the phase-reversed second echo signal.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: July 20, 2021
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventor: Masaaki Ishitsuka
  • Patent number: 11031990
    Abstract: A technique comprising: receiving a set of digital signals representative of a set of analogue electrical signals generated by radio transmissions in one or more antenna elements; generating at least two beamformed signals from the same set of digital signals; multiplying together said beamformed signals; and performing demodulation at least partially on an output of multiplying said beamformed signals.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: June 8, 2021
    Assignee: NOKIA TECHNOLOGIES OY
    Inventors: Wolfgang Zirwas, Muhammad Bilal Amin
  • Patent number: 11020143
    Abstract: A steering adjustment for a needle visualization ultrasound system includes a needle, an ultrasound interface and one or more processing electronics. The ultrasound interface receives ultrasound imaging information from a first set of ultrasound firings. The processing electronics are coupled to the ultrasound interface. The processing electronics utilize the information from the first set of firings and identify the angle of the needle and the optimized steering frame angle. The processing electronics are further configured to cause a second set of firings. The second set of firings are configured for the identified needle angle and steering frame angle. The processing electronics are further configured to utilize the ultrasound information from the second set of firings to adaptively and dynamically enhance the visualization of the needle.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: June 1, 2021
    Assignee: EDAN INSTRUMENTS, INC.
    Inventors: Seshadri Srinivasan, Ling Feng
  • Patent number: 10993611
    Abstract: Methods and systems for assessing regional variations in aqueous outflow vessels of the eye and for optimizing locations within the eye stent implantation or other surgical procedures intended to increase aqueous outflow and reduce intraocular pressure.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: May 4, 2021
    Assignee: The Regents of the University of California
    Inventors: Sameh Mosaed, Ken Lin
  • Patent number: 10890661
    Abstract: A method of forming an image of a region of interest using a pulse-echo imaging device is described. The method includes the steps of transmitting a pulse, discriminating an echo of the pulse by comparison to a plurality of Hermite polynomials, and determining a color for display based on the comparison. A system for forming an image of a region of interest is also described. The system includes a pulse-echo imaging device for transmitting a pulse and a control unit in communication with the pulse-echo imaging device. The control unit is configured to discriminate an echo of the pulse by comparison to a plurality of Hermite polynomials and determine a color for display based on the comparison.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: January 12, 2021
    Assignee: UNIVERSITY OF ROCHESTER
    Inventor: Kevin J. Parker
  • Patent number: 10799219
    Abstract: A system and a method of ultrasound imaging includes acquiring ultrasound data, acquiring a quality parameter while acquiring the ultrasound data, determining an acquisition quality level based on the quality parameter, displaying an image generated based on the ultrasound data and displaying an ROI on the ultrasound image, where a color of the ROI represents the acquisition quality level.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: October 13, 2020
    Assignee: General Electric Company
    Inventors: Tanya Specht, Menachem Halmann, Alexander Sokulin, Peter Lysyansky, Cynthia Owen, Sergey Ogurtsov
  • Patent number: 10792014
    Abstract: An ultrasound inspection apparatus includes a region setting section setting a plurality of regions within the inspection object; a sound velocity calculator calculating a sound velocity of each of the plurality of regions; a sound velocity obtainer obtaining a preliminary sound velocity of a region of interest; and an image quality determiner determining an image quality of the region of interest based on the preliminary sound velocity. The preliminary sound velocity obtained by the sound velocity obtainer is employed as a sound velocity of the region of interest when a determination result made by the image quality determiner is positive, and the sound velocity of the region of interest is calculated by the sound velocity calculator when the determination result is negative.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: October 6, 2020
    Assignee: FUJIFILM Corporation
    Inventor: Hiroaki Yamamoto
  • Patent number: 10751015
    Abstract: Devices, systems, and methods of evaluating risk associated with a condition of the vessel and issuing an automatic recommendation based on co-registered physiological measurements are disclosed. The includes steps of obtaining image data for the vessel of the patient, obtaining physiological measurements for the vessel of the patient, co-registering the obtained physiological measurements with the obtained image data such that the physiological measurements are associated with corresponding portions of the vessel of the patient, analyzing the co-registered physiology measurements to identify a region of interest, and outputting, to a user interface, a suggested diagnostic procedure for the region of interest based on the analysis of the co-registered physiology measurements.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: August 25, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: David Anderson, Fergus Merritt
  • Patent number: 10751028
    Abstract: Ultrasonic imaging is performed by constructing spatial coherence images of a target having microbubbles in it. The basis for this approach is the observation that the spatial coherence of microbubbles differs from the spatial coherence of tissue and the spatial coherence of image noise. Therefore, imaging based on spatial coherence provides a way to suppress noise signals and tissue signals relative to the microbubble signals.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: August 25, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jeremy Joseph Dahl, Dongwoon Hyun, Juergen K. Willmann
  • Patent number: 10670581
    Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: June 2, 2020
    Assignee: Purdue Research Foundation
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Patent number: 10631730
    Abstract: Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: April 28, 2020
    Assignee: Oregon Health & Science University
    Inventors: David Huang, Yali Jia, Miao Zhang
  • Patent number: 10591325
    Abstract: A flow feature detection method is described. The method includes storing a plurality of points at locations over a region in which vortex detection is to be performed. A value for each of a plurality of fluid flow parameters, such as velocity, pressure and density, is determined at each point. The points are grouped as being contained in either a flow feature portion or normal flow portion of the region according to one or more statistical distribution for the fluid flow parameters. A point is identified as being indicative of the flow feature by identifying multiple further points at least partially surrounding the point, and determining a plane in which the flow feature is identifiable based upon the relative values of the one or more fluid flow parameter for the further points. The method may be used to detect vortices and to identify a two-dimensional plane representative of a vortex.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: March 17, 2020
    Assignee: ROLLS-ROYCE plc
    Inventors: Yiping Ke, Jian Cheng Wong, Chi-Keong Goh, Kee Khoon Lee
  • Patent number: 10512452
    Abstract: For estimating attenuation in ultrasound imaging, displacements at different locations along an acoustic radiation force impulse (ARFI) beam are used measured. The on-axis displacements and displacements from a phantom using a same ARFI focus as a reference are used to cancel out focusing effects. A single ARFI beam may be used to estimate the attenuation for a location.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: December 24, 2019
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Yassin Labyed, Liexiang Fan
  • Patent number: 10507315
    Abstract: A catheter system including an elongate tubular member having a proximal end portion, a distal end portion and a lumen extending through at least a portion of a length of the elongate tubular member. The distal end portion of the elongate member is dimensioned and adapted to advance to or in proximity to a treatment site of a subject. A microbubble device is in fluid communication with the lumen. The microbubble device includes at least one input port for receiving a flow of material into the device and an output port configured to output microbubbles from the microbubble device. A second tubular member is in fluid communication with one of the at least one input ports. A pressure fitting arrangement is adapted to maintain a seal between the second tubular member and the input port.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: December 17, 2019
    Assignee: University of Virginia Patent Foundation
    Inventors: John A. Hossack, Brian R. Wamhoff, Alexander L. Klibanov, Johnny Chen, Brent A. French
  • Patent number: 10499813
    Abstract: In part, the disclosure relates to systems for imaging a blood vessel using intravascular image data and extravascular image data and methods to calibrate such systems. In one embodiment, multiple calibration trials are performed to determine a plurality of time lag values. A minimum time lag value is used to align intravascular image data and extravascular time lag data in one embodiment.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: December 10, 2019
    Assignee: LIGHTLAB IMAGING, INC.
    Inventor: Desmond Adler
  • Patent number: 10456114
    Abstract: Provided is a method of marking a diffusion boundary of medicine, the method performed by an ultrasound apparatus and including operations of obtaining first B mode image data and first Doppler data about a target object to which the medicine is injected; detecting a first area of the target object from which the first Doppler data is obtained; determining a first diffusion boundary of the medicine, based on the first area; and marking the first diffusion boundary of the medicine on a B mode image that is generated by using the first B mode image data.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: October 29, 2019
    Assignees: Samsung Medison Co., Ltd., Samsung Electronics Co., Ltd.
    Inventors: Eun-mi Cho, Jung-taek Oh, Eun-yeong Kim
  • Patent number: 10453193
    Abstract: Various methods and systems are provided for shading a 2D ultrasound image, generated from ultrasound data, using a gradient determined from scalar values of the ultrasound image data. As one example, a method includes correlating image values of a dataset acquired with an ultrasound imaging system to height values; determining a gradient of the height values; applying shading to a 2D image generated from the dataset using the determined gradient; and displaying the shaded 2D image.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: October 22, 2019
    Assignee: General Electric Company
    Inventors: Gerald Schroecker, Daniel John Buckton
  • Patent number: 10448850
    Abstract: Methods for measuring blood flow speed within blood vessels using a PA imaging system are disclosed. The methods include position a field of view of a PA imaging system along a section of a blood vessel, introducing a PA discontinuity into the blood flow within the blood vessel upstream of the FOV of the PA system, monitoring the movement of the PA discontinuity during movement through the FOV of the PA imaging device, and calculate the blood flow speed using at least two measured positions and corresponding times of the PA discontinuity within the FOV of the PA imaging system. PA discontinuities may include blood surges formed by compressing and releasing the blood vessel and/or boluses of a fluid with high PA contrast relative to the blood, such as saline solution.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: October 22, 2019
    Assignee: Washington University
    Inventors: Lihong Wang, Yong Zhou
  • Patent number: 10410608
    Abstract: An electronic device and a method for displaying an image transmitted by a robot and remotely controlling a movement of the robot are provided. The electronic device includes a communicator, an inputter, a display, and a controller. The communicator receives, from the robot, an image photographed by the robot and time information. The inputter receives a command to control the robot. The display displays a screen corresponding to the image. The controller calculates a time delay between the electronic device and the robot based on the time information, control the display to display a graphical object to be overlaid on the screen, and control the communicator to transmit the command to the robot. The graphical object represents a field of view of the robot at a current time. The field of view of the robot at the current time may be estimated based on the time delay information.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 10, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yoon-sang Kim, Jae-keun Na, Ho-chul Shin
  • Patent number: 10345268
    Abstract: An ultrasonic transmitter 3 attached to an inspecting target object 1, an ultrasonic receiver 5 receiving a reflected wave of the ultrasonic wave that has propagated from the ultrasonic transmitter 3 in the inspecting target object, a data processing device 7 acquiring position specifying data for specifying a position of a defect 1a in the inspecting target object 1 on the basis of received data representing a waveform of the reflected wave received by the ultrasonic receiver 5 are provided. The ultrasonic wave generated by the ultrasonic transmitter 3 has been frequency-modulated, and has a waveform composed of components of respective frequencies that are deviated from a resonance frequency of the ultrasonic transmitter 3 and the ultrasonic receiver 5. The data processing device 7 includes a pulse compressing unit 21 performing pulse compression on the received data, and acquires the position specifying data on the basis of the pulse-compressed received data.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: July 9, 2019
    Assignee: IHI Inspection and Instrumentation Co., Ltd.
    Inventors: Hiraku Kawasaki, Tatsuya Hikichi, Saburou Shibata, Hideyuki Nakamura, Takahiro Arakawa
  • Patent number: 10278612
    Abstract: A solution for diagnostic applications is proposed. Particularly, a corresponding diagnostic system includes means (903-906) for providing (A1-A3) a plurality of input signals representative of a body-part being perfused with a contrast agent over time, each input signal being indicative of a response to an interrogating stimulus of a corresponding location of the body-part possibly including the contrast agent, means (909-930) for generating (A4.1-A4.3) a plurality of filtered signals from selected input signals of selected locations, each filtered signal at each instant over time being generated from a corresponding selected input signal according to a portion of the selected input signal including said instant, and means (933-939) for monitoring (A4.4-A4.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: May 7, 2019
    Assignee: Bracco Suisse SA
    Inventors: Peter Frinking, Laurent Mercier, Nicolas Rognin, Marcel Arditi
  • Patent number: 10217443
    Abstract: An electronic device and a method for displaying an image transmitted by a robot and remotely controlling a movement of the robot are provided. The electronic device includes a communicator, an inputter, a display, and a controller. The communicator receives, from the robot, an image photographed by the robot and time information. The inputter receives a command to control the robot. The display displays a screen corresponding to the image. The controller calculates a time delay between the electronic device and the robot based on the time information, control the display to display a graphical object to be overlaid on the screen, and control the communicator to transmit the command to the robot. The graphical object represents a field of view of the robot at a current time. The field of view of the robot at the current time may be estimated based on the time delay information.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: February 26, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yoon-sang Kim, Jae-keun Na, Ho-chul Shin
  • Patent number: 10213189
    Abstract: A needle includes a surface with a plurality of first ultrasound reflecting depressions formed therein. The first depressions are distributed along at least a portion of a length of the needle separated from one another by intervening sections. Each of the first depressions is extending along a curve between first and second ends adjacent to corresponding ones of the intervening sections with troughs at which surfaces of each of the first depressions most closely approach a longitudinal axis of the needle being offset toward the first ends of each of the first depressions.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: February 26, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Shawn Ryan
  • Patent number: 10159781
    Abstract: A method for implanting a cardiac support device (CSD) on a patient's heart. An amount of contrast agent sufficient to cause structures on the heart to be visible upon fluoroscopic or other imaging is introduced into the pericardial space surrounding the heart. The heart and contrast agent are imaged to provide a visual indication of the location of the structures of the heart. The CSD is placed on the heart using the visual indications provided by the imaging.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: December 25, 2018
    Assignee: Mardil, Inc.
    Inventors: William E. Cohn, Aaron J. Hjelle, Robert G. Walsh, Kevin Paul Bassett
  • Patent number: 10143455
    Abstract: Methods and devices for providing improved ultrasound visibility of medical devices intended for intravascular use are described. The inclusion of gas/solid boundary regions within a medical devices improves the resolution of the device under ultrasound visualization. Gas/solid boundary regions may be provided through the use of embedded gas-filled microlumens, microwells, or enclosed pockets within the medical device.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: December 4, 2018
    Assignee: Covidien LLP
    Inventors: Robert C. Lichty, II, Jan R. Lau, Rodney D. Raabe, Monte Madsen
  • Patent number: 10105070
    Abstract: A catheter to access and navigate the uterine cavity through the cervical canal for delivering, deploying, and facilitating operation of a peripheral intrauterine medical apparatus during parturition includes an elongated, flexible tubular catheter body with a handle at the proximal end controlling a steering mechanism and deflecting the distal tip. The catheter includes a lumen that extends the length of catheter body to a distal end region of the catheter. The peripheral medical apparatus is located in the distal end region and is configured to deploy from the distal tip of the catheter into the uterine cavity. A soft catheter tip reduces the likelihood of injury during intrauterine navigation and placement, and sensors associated with the catheter body provide signals that allow for the monitoring of infant, umbilical cord, placenta and uterine muscle activity during labor to assist operation of the peripheral medical apparatus.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: October 23, 2018
    Assignee: 3VO Medical, Inc.
    Inventors: Ed Chinchoy, James Kelley, Jay Snell
  • Patent number: 10086150
    Abstract: A method for manufacturing a needle tapered along the longitudinal direction by electroforming comprises: a step of immersing a core material (122) having an outer peripheral surface that is tapered along the longitudinal direction in an electrolyte and forming a first electroformed body (126) on an outer peripheral surface (124) of the core material (122); a step of immersing the first electroformed body (126) in an electrolyte to which particles having a prescribed particle size are added and forming a second electroformed body (134) having multiple protrusions (30) on an outer peripheral surface (128) of the first electroformed body (126); a step of cutting the first electroformed body (126) and second electroformed body (134) into a prescribed length and forming a needle (10) having a sharp needle tip (16); and a step of pulling out the core material (122) from the cut first electroformed body (126).
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: October 2, 2018
    Assignee: EFR CO., LTD.
    Inventors: Akitoshi Tomihara, Terumi Takimiya, Tetsuo Tanaka
  • Patent number: 10012724
    Abstract: Provided are an ultrasonic diagnostic apparatus that is capable of generating an image caused by fundamental components of ultrasonic echo signals and synthesizing the generated image with an image caused by harmonic components so that an image having both advantages of the images can be generated, and a method of controlling the ultrasonic diagnostic apparatus.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: July 3, 2018
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventor: Deok Gon Kim
  • Patent number: 9993631
    Abstract: A ventriculoperitoneal shunt includes a proximal catheter, a distal catheter, a shunt valve operably coupling the proximal catheter to the distal catheter, and a contrast container containing contrast material configured to change acoustic impedance proportionally to a change in pressure applied to the contrast container.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: June 12, 2018
    Assignee: The Johns Hopkins University
    Inventors: George L. Coles, Jr., Sybil Klaus, Eric Jackson, Philippe M. Burlina, Richard S. Potember, Wayne I. Sternberger, John H. Benson, Benjamin Elder
  • Patent number: 9968692
    Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: May 15, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Patent number: 9943289
    Abstract: An ultrasound imaging system includes an ultrasound transducer array that receives a set of echo signals produced in response to an ultrasound signal traversing flowing structure in a portion of a tubular structure of an object or subject in an imaging field of view. An image processor processes the set of echo signals and generates a structure image. A color flow processor processes the set of echo signals and generates a color flow image indicative of a flow of the flowing structure in the portion of the tubular structure, including a flow direction and a flow magnitude of the flowing structure. A color flow corrector corrects the color flow image for at least one of color noise artifact or color flash artifact, producing a corrected color flow image. A video processor displays the structure image and the corrected color flow image superimposed over the structure image.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: April 17, 2018
    Assignee: B-K Medical Aps
    Inventor: Bo Martins
  • Patent number: 9940736
    Abstract: According to one embodiment, a medical image diagnostic apparatus includes a storage memory, processing circuitry, and a display. The storage memory stores data of a plurality of FFR distribution maps constituting a time series regarding a coronary artery, and data of a plurality of morphological images corresponding to the time series. The processing circuitry converts the plurality of FFR distribution maps into a plurality of corresponding color maps, respectively. The display displays a plurality of superposed images obtained by superposing the plurality of color maps and the plurality of morphological images respectively corresponding in phase to the plurality of color maps. The display restricts display targets for the plurality of color maps based on the plurality of FFR distribution maps or the plurality of morphological images.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: April 10, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Hideaki Ishii, Satoshi Wakai, Kazumasa Arakita, Takuma Igarashi, Yasuko Fujisawa, Shigeo Kaminaga, Kenji Hirohata, Junichiro Ooga
  • Patent number: 9939413
    Abstract: Measurement or imaging of elastic wave nonlinear scatterers with a memory of scattering parameters comprises selecting LF pulses having characteristics to change the scattering parameters of nonlinear scatterers. A transmit time relation is selected so that the incident HF pulse propagates sufficiently close to the LF pulse that the effect of the incident LF pulse on its scatterer parameters is observed by the HF pulse. At least two elastic wave pulse complexes comprising a high frequency (HF) pulse and a selected low frequency (LF) pulse are transmitted towards the region. Received HF signals are combined to form nonlinear HF signals representing the scatterers with memory, with suppression of received HF signals from other scatterers. At least one of the received HF signals may be corrected by time delay correction and/or speckle correction with a speckle correction filter, determined by movement of the scattering object. Systems are also disclosed.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: April 10, 2018
    Assignee: SURF Technology AS
    Inventors: Bjørn A. J. Angelsen, Rune Hansen, Tonni F. Johansen, Svein-Erik Måsøy, Sven Peter Nasholm, Thor Andreas Tangen
  • Patent number: 9861385
    Abstract: A surgical needle having notches in a sidewall with enhanced ultrasound reflectivity is disclosed. Indentations, ridges, projections, overhanging edges, and other structures are formed in the notches to retain small amounts of air or other reflective material as the surgical needle is passed through tissue. The additional amounts of reflective material retained by these structures will significantly enhance the ultrasound reflectivity and enhance the response to ultrasonic probing to provide an enhanced image during needle placement in a medical patient so that the needle may be accurately placed as desired. Alternatively or additionally, the notches are filled with a substance that contains air bubbles suspended in the substance wherein the suspended air bubbles provide the reflectivity enhancement. In both embodiments, the needle will be visible at any angle in which the device is used in a medical patient.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: January 9, 2018
    Assignee: NFINIUM VASCULAR TECHNOLOGIES, LLC
    Inventor: Richard Eustis Fulton
  • Patent number: 9773307
    Abstract: The present invention provides quantification and imaging methods and a system of the echo-texture feature, comprising: obtaining an ultrasonic image; calculating all the pixel values in a selected ROI of the ultrasonic image to obtain a regional standard deviation; excluding pixels with a pixel value smaller than a multiple of the regional standard deviation in the selected ROI; counting a set of pixels centered around a Nth pixel to gather a Nth local mean, a Nth local variance and a Nth local coefficient of variance corresponding the set of pixel values, wherein N is from 1 to the number of the pixels remaining in the selected ROI; and obtaining an echo-texture index according to the local means, the local variances, or the local coefficient of variances. The imaging of echo texture which shows the echo texture distribution of the selected ROI with a color scale changing continuously from red to blue is also included. A parameter is provided to adjust the visualization enhancement of the echo texture.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: September 26, 2017
    Assignee: AMCAD BIOMED CORPORATION
    Inventors: King-Jen Chang, Argon Chen, Chiung-Nein Chen, Kuen Yuan Chen, Yu-Hsin Wang, Kuo-Chen Huang
  • Patent number: 9636082
    Abstract: An embryo replacement catheter has a flexible extruded shaft of a transparent polyurethane with a bore extending along its length. Gas bubbles of a diameter in the range 5 .mu. to 10 .mu. are incorporated into the thickness of the wall of the shaft by adding gas during extrusion. The bubbles are selected to increase the visibility of the catheter under ultrasound imaging while still enabling material flowing along the catheter to be seen. The inventive catheter is not confined to embryo replacement catheters.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: May 2, 2017
    Assignee: The Cooper Companies Global Holdings LP
    Inventor: Stephen James Field
  • Patent number: 9592352
    Abstract: An ultrasound-guided piercing needle constituting the internal needle of an indwelling needle has ridged and grooved portions which reflect ultrasonic waves. The ridged and grooved portions comprise grooves, which are disposed on the outer periphery near the tip having a blade face, and ridges, which are arranged on both sides of the grooves.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: March 14, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Masaki Matsuzawa
  • Patent number: 9576357
    Abstract: Ultrasonic imaging methods are described for eliminating the effects of physiological motion such as respiratory motion from image data of a sequence of images which is to be used for quantified analysis such as time-intensity curve computation. A bright reflector in the images of the loop which exhibits motional effects such as cyclical variation in brightness or position from image to image is identified and its variation used to identify cycles of motion. A phase or range of phases of the cycles is identified. Images acquired during the identified phase or phase range of the motion cycles during the loop are then used for quantified processing.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: February 21, 2017
    Assignee: Koninklijke Philips N.V.
    Inventors: Michalakis Averikou, Damianos Christophides
  • Patent number: 9561017
    Abstract: The present disclosure provides for a system that is adapted to simultaneously display photoacoustic and ultrasound images of the same object. An image combiner can perform spatial and temporal interpolation of the two images before generating a combined image. The combined image is then displayed on a display such as an LCD or CRT. The system is able to use motion estimates obtained from the ultrasound data to enhance the photoacoustic image thereby increasing its apparent frame rate, registering consecutive frames in order to reduce artifacts. The system is capable of generating combined ultrasound and photoacoustic images which are registered spatially and temporally.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: February 7, 2017
    Assignee: Koninklijke Philips N.V.
    Inventor: Michael Burcher
  • Patent number: 9521993
    Abstract: A needle includes a surface with a plurality of first ultrasound reflecting depressions formed therein. The first depressions are distributed along at least a portion of a length of the needle separated from one another by intervening sections. Each of the first depressions is extending along a curve between first and second ends adjacent to corresponding ones of the intervening sections with troughs at which surfaces of each of the first depressions most closely approach a longitudinal axis of the needle being offset toward the first ends of each of the first depressions.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: December 20, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Shawn Ryan
  • Patent number: 9456806
    Abstract: A biopsy probe mechanism includes an elongate sample receiving member having a longitudinal axis and having a sample receiving notch. The elongate sample receiving member and a cutting cannula are movable relative to one another along a longitudinal axis. A first echogenic feature is established on the elongate sample receiving member and a second echogenic feature is established on the cutting cannula. The elongate sample receiving member and the cutting cannula are configured to have a first position in which the first echogenic feature is in longitudinal alignment with the second echogenic feature, and configured such that when the elongate sample receiving member and the cutting cannula are moved relative to one another from the first position, the first echogenic feature and the second echogenic feature are out of longitudinal alignment.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: October 4, 2016
    Assignee: C.R. Bard, Inc.
    Inventors: Rafal Chudzik, Jason G. Seiger, Jennifer Smith, Charles Simpson
  • Patent number: 9433373
    Abstract: The present subject matter provides apparatus and methods for physically fitting a hearing assistance device, including mathematically characterizing a person's ear canal. The apparatus includes a housing adapted to be mechanically coupled to the person in proximity to the person's outer ear. An ultrasonic transducer array is located within at least a portion of the housing. The apparatus includes electronics within the housing, the electronics adapted to control the transducer array to alternate between transmitting and receiving ultrasonic energy. In various embodiments, a processor is adapted to characterize geometry of the ear canal using information from the ultrasonic transducer array obtained from scans of the ear canal.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: September 6, 2016
    Assignee: Starkey Laboratories, Inc.
    Inventor: Thomas Howard Burns
  • Patent number: 9409001
    Abstract: A balloon catheter includes a balloon having a plurality of layers. The inner layer acts as a support layer to the outer layer. Embedded within the outer layer is a plurality of particles or pellets which in one embodiment provide roughening of the outer surface of the balloon. The particles or pellets, particularly in conjunction with an inner support layer, ensure maintenance of the roughened outer surface of the balloon during inflation of the balloon. In another embodiment, the particles or pellets may be radiopaque and/or echogenic with or without creating surface roughening of the balloon.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: August 9, 2016
    Assignee: Cook Medical Technologies LLC
    Inventors: Steen Aggerholm, Anders Scheel Klausen, Thomas Lysgaard, Anne-Mette Hoppe Sönnichsen, Allan Torp
  • Patent number: 9370338
    Abstract: Disclosed is an ultrasound diagnosis device for creating an ultrasound image with a high contrast-to-tissue ratio. Said device sends a transmission pulse to the subject, uses an ultrasound probe to receive echoes reflected from an ultrasound contrast agent injected into the subject, and forms an image. The transmission pulse is sent such that nonlinear interactions between the constituent frequency components of said transmission pulse, as a result of the acoustic nonlinearity of the subject, do not produce sum and difference components in the frequency sensitivity range of the ultrasonic probe as the transmission pulse propagates across the subject.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: June 21, 2016
    Assignee: HITACHI MEDICAL CORPORATION
    Inventors: Kunio Hashiba, Hideki Yoshikawa, Tatsuya Hayashi
  • Patent number: 9291493
    Abstract: The invention presents methods and instrumentation for measurement or imaging of a region of an object with waves of a general nature, for example electromagnetic (EM) and elastic (EL) waves, where the material parameters for wave propagation and scattering in the object depend on the wave field strength. The invention specially addresses suppression of 3rd order multiple scattering noise, referred to as pulse reverberation noise, and also suppression of linear scattering components to enhanced signal components from nonlinear scattering. The pulse reverberation noise is divided into three classes where the invention specially addresses Class I and Class II 3rd order multiple scattering that are generated from the same three scatterers, but in opposite sequence.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: March 22, 2016
    Assignee: SURF Technology AS
    Inventors: Bjørn A. J. Angelsen, Thor Andreas Tangen
  • Patent number: 9261596
    Abstract: A method for ultrasound imaging of anatomical tissue. A first signal is received from a first imaging ultrasound wave which has been reflected from a location in the anatomical tissue during a first time period. A second signal is received from a second imaging ultrasound wave which has been reflected from the location in the anatomical tissue during a later second time period, following a discrete medical treatment. The second signal is subtracted from the first signal to form a difference signal. The difference signal may be scaled, spatially filtered, then used to generate an indication, the indication showing the effect of the medical treatment in the location in the anatomical tissue.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: February 16, 2016
    Inventors: T. Douglas Mast, Waseem Faidi, Inder Raj S. Makin, Peter G. Barthe, Michael H. Slayton