Contrast Enhancement Patents (Class 600/458)
  • Patent number: 10345268
    Abstract: An ultrasonic transmitter 3 attached to an inspecting target object 1, an ultrasonic receiver 5 receiving a reflected wave of the ultrasonic wave that has propagated from the ultrasonic transmitter 3 in the inspecting target object, a data processing device 7 acquiring position specifying data for specifying a position of a defect 1a in the inspecting target object 1 on the basis of received data representing a waveform of the reflected wave received by the ultrasonic receiver 5 are provided. The ultrasonic wave generated by the ultrasonic transmitter 3 has been frequency-modulated, and has a waveform composed of components of respective frequencies that are deviated from a resonance frequency of the ultrasonic transmitter 3 and the ultrasonic receiver 5. The data processing device 7 includes a pulse compressing unit 21 performing pulse compression on the received data, and acquires the position specifying data on the basis of the pulse-compressed received data.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: July 9, 2019
    Assignee: IHI Inspection and Instrumentation Co., Ltd.
    Inventors: Hiraku Kawasaki, Tatsuya Hikichi, Saburou Shibata, Hideyuki Nakamura, Takahiro Arakawa
  • Patent number: 10278612
    Abstract: A solution for diagnostic applications is proposed. Particularly, a corresponding diagnostic system includes means (903-906) for providing (A1-A3) a plurality of input signals representative of a body-part being perfused with a contrast agent over time, each input signal being indicative of a response to an interrogating stimulus of a corresponding location of the body-part possibly including the contrast agent, means (909-930) for generating (A4.1-A4.3) a plurality of filtered signals from selected input signals of selected locations, each filtered signal at each instant over time being generated from a corresponding selected input signal according to a portion of the selected input signal including said instant, and means (933-939) for monitoring (A4.4-A4.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: May 7, 2019
    Assignee: Bracco Suisse SA
    Inventors: Peter Frinking, Laurent Mercier, Nicolas Rognin, Marcel Arditi
  • Patent number: 10213189
    Abstract: A needle includes a surface with a plurality of first ultrasound reflecting depressions formed therein. The first depressions are distributed along at least a portion of a length of the needle separated from one another by intervening sections. Each of the first depressions is extending along a curve between first and second ends adjacent to corresponding ones of the intervening sections with troughs at which surfaces of each of the first depressions most closely approach a longitudinal axis of the needle being offset toward the first ends of each of the first depressions.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: February 26, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Shawn Ryan
  • Patent number: 10217443
    Abstract: An electronic device and a method for displaying an image transmitted by a robot and remotely controlling a movement of the robot are provided. The electronic device includes a communicator, an inputter, a display, and a controller. The communicator receives, from the robot, an image photographed by the robot and time information. The inputter receives a command to control the robot. The display displays a screen corresponding to the image. The controller calculates a time delay between the electronic device and the robot based on the time information, control the display to display a graphical object to be overlaid on the screen, and control the communicator to transmit the command to the robot. The graphical object represents a field of view of the robot at a current time. The field of view of the robot at the current time may be estimated based on the time delay information.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: February 26, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yoon-sang Kim, Jae-keun Na, Ho-chul Shin
  • Patent number: 10159781
    Abstract: A method for implanting a cardiac support device (CSD) on a patient's heart. An amount of contrast agent sufficient to cause structures on the heart to be visible upon fluoroscopic or other imaging is introduced into the pericardial space surrounding the heart. The heart and contrast agent are imaged to provide a visual indication of the location of the structures of the heart. The CSD is placed on the heart using the visual indications provided by the imaging.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: December 25, 2018
    Assignee: Mardil, Inc.
    Inventors: William E. Cohn, Aaron J. Hjelle, Robert G. Walsh, Kevin Paul Bassett
  • Patent number: 10143455
    Abstract: Methods and devices for providing improved ultrasound visibility of medical devices intended for intravascular use are described. The inclusion of gas/solid boundary regions within a medical devices improves the resolution of the device under ultrasound visualization. Gas/solid boundary regions may be provided through the use of embedded gas-filled microlumens, microwells, or enclosed pockets within the medical device.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: December 4, 2018
    Assignee: Covidien LLP
    Inventors: Robert C. Lichty, II, Jan R. Lau, Rodney D. Raabe, Monte Madsen
  • Patent number: 10105070
    Abstract: A catheter to access and navigate the uterine cavity through the cervical canal for delivering, deploying, and facilitating operation of a peripheral intrauterine medical apparatus during parturition includes an elongated, flexible tubular catheter body with a handle at the proximal end controlling a steering mechanism and deflecting the distal tip. The catheter includes a lumen that extends the length of catheter body to a distal end region of the catheter. The peripheral medical apparatus is located in the distal end region and is configured to deploy from the distal tip of the catheter into the uterine cavity. A soft catheter tip reduces the likelihood of injury during intrauterine navigation and placement, and sensors associated with the catheter body provide signals that allow for the monitoring of infant, umbilical cord, placenta and uterine muscle activity during labor to assist operation of the peripheral medical apparatus.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: October 23, 2018
    Assignee: 3VO Medical, Inc.
    Inventors: Ed Chinchoy, James Kelley, Jay Snell
  • Patent number: 10086150
    Abstract: A method for manufacturing a needle tapered along the longitudinal direction by electroforming comprises: a step of immersing a core material (122) having an outer peripheral surface that is tapered along the longitudinal direction in an electrolyte and forming a first electroformed body (126) on an outer peripheral surface (124) of the core material (122); a step of immersing the first electroformed body (126) in an electrolyte to which particles having a prescribed particle size are added and forming a second electroformed body (134) having multiple protrusions (30) on an outer peripheral surface (128) of the first electroformed body (126); a step of cutting the first electroformed body (126) and second electroformed body (134) into a prescribed length and forming a needle (10) having a sharp needle tip (16); and a step of pulling out the core material (122) from the cut first electroformed body (126).
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: October 2, 2018
    Assignee: EFR CO., LTD.
    Inventors: Akitoshi Tomihara, Terumi Takimiya, Tetsuo Tanaka
  • Patent number: 10012724
    Abstract: Provided are an ultrasonic diagnostic apparatus that is capable of generating an image caused by fundamental components of ultrasonic echo signals and synthesizing the generated image with an image caused by harmonic components so that an image having both advantages of the images can be generated, and a method of controlling the ultrasonic diagnostic apparatus.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: July 3, 2018
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventor: Deok Gon Kim
  • Patent number: 9993631
    Abstract: A ventriculoperitoneal shunt includes a proximal catheter, a distal catheter, a shunt valve operably coupling the proximal catheter to the distal catheter, and a contrast container containing contrast material configured to change acoustic impedance proportionally to a change in pressure applied to the contrast container.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: June 12, 2018
    Assignee: The Johns Hopkins University
    Inventors: George L. Coles, Jr., Sybil Klaus, Eric Jackson, Philippe M. Burlina, Richard S. Potember, Wayne I. Sternberger, John H. Benson, Benjamin Elder
  • Patent number: 9968692
    Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: May 15, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Joseph Irudayaraj, Pushpak Bhandari
  • Patent number: 9943289
    Abstract: An ultrasound imaging system includes an ultrasound transducer array that receives a set of echo signals produced in response to an ultrasound signal traversing flowing structure in a portion of a tubular structure of an object or subject in an imaging field of view. An image processor processes the set of echo signals and generates a structure image. A color flow processor processes the set of echo signals and generates a color flow image indicative of a flow of the flowing structure in the portion of the tubular structure, including a flow direction and a flow magnitude of the flowing structure. A color flow corrector corrects the color flow image for at least one of color noise artifact or color flash artifact, producing a corrected color flow image. A video processor displays the structure image and the corrected color flow image superimposed over the structure image.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: April 17, 2018
    Assignee: B-K Medical Aps
    Inventor: Bo Martins
  • Patent number: 9940736
    Abstract: According to one embodiment, a medical image diagnostic apparatus includes a storage memory, processing circuitry, and a display. The storage memory stores data of a plurality of FFR distribution maps constituting a time series regarding a coronary artery, and data of a plurality of morphological images corresponding to the time series. The processing circuitry converts the plurality of FFR distribution maps into a plurality of corresponding color maps, respectively. The display displays a plurality of superposed images obtained by superposing the plurality of color maps and the plurality of morphological images respectively corresponding in phase to the plurality of color maps. The display restricts display targets for the plurality of color maps based on the plurality of FFR distribution maps or the plurality of morphological images.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: April 10, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Hideaki Ishii, Satoshi Wakai, Kazumasa Arakita, Takuma Igarashi, Yasuko Fujisawa, Shigeo Kaminaga, Kenji Hirohata, Junichiro Ooga
  • Patent number: 9939413
    Abstract: Measurement or imaging of elastic wave nonlinear scatterers with a memory of scattering parameters comprises selecting LF pulses having characteristics to change the scattering parameters of nonlinear scatterers. A transmit time relation is selected so that the incident HF pulse propagates sufficiently close to the LF pulse that the effect of the incident LF pulse on its scatterer parameters is observed by the HF pulse. At least two elastic wave pulse complexes comprising a high frequency (HF) pulse and a selected low frequency (LF) pulse are transmitted towards the region. Received HF signals are combined to form nonlinear HF signals representing the scatterers with memory, with suppression of received HF signals from other scatterers. At least one of the received HF signals may be corrected by time delay correction and/or speckle correction with a speckle correction filter, determined by movement of the scattering object. Systems are also disclosed.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: April 10, 2018
    Assignee: SURF Technology AS
    Inventors: Bjørn A. J. Angelsen, Rune Hansen, Tonni F. Johansen, Svein-Erik Måsøy, Sven Peter Nasholm, Thor Andreas Tangen
  • Patent number: 9861385
    Abstract: A surgical needle having notches in a sidewall with enhanced ultrasound reflectivity is disclosed. Indentations, ridges, projections, overhanging edges, and other structures are formed in the notches to retain small amounts of air or other reflective material as the surgical needle is passed through tissue. The additional amounts of reflective material retained by these structures will significantly enhance the ultrasound reflectivity and enhance the response to ultrasonic probing to provide an enhanced image during needle placement in a medical patient so that the needle may be accurately placed as desired. Alternatively or additionally, the notches are filled with a substance that contains air bubbles suspended in the substance wherein the suspended air bubbles provide the reflectivity enhancement. In both embodiments, the needle will be visible at any angle in which the device is used in a medical patient.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: January 9, 2018
    Assignee: NFINIUM VASCULAR TECHNOLOGIES, LLC
    Inventor: Richard Eustis Fulton
  • Patent number: 9773307
    Abstract: The present invention provides quantification and imaging methods and a system of the echo-texture feature, comprising: obtaining an ultrasonic image; calculating all the pixel values in a selected ROI of the ultrasonic image to obtain a regional standard deviation; excluding pixels with a pixel value smaller than a multiple of the regional standard deviation in the selected ROI; counting a set of pixels centered around a Nth pixel to gather a Nth local mean, a Nth local variance and a Nth local coefficient of variance corresponding the set of pixel values, wherein N is from 1 to the number of the pixels remaining in the selected ROI; and obtaining an echo-texture index according to the local means, the local variances, or the local coefficient of variances. The imaging of echo texture which shows the echo texture distribution of the selected ROI with a color scale changing continuously from red to blue is also included. A parameter is provided to adjust the visualization enhancement of the echo texture.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: September 26, 2017
    Assignee: AMCAD BIOMED CORPORATION
    Inventors: King-Jen Chang, Argon Chen, Chiung-Nein Chen, Kuen Yuan Chen, Yu-Hsin Wang, Kuo-Chen Huang
  • Patent number: 9636082
    Abstract: An embryo replacement catheter has a flexible extruded shaft of a transparent polyurethane with a bore extending along its length. Gas bubbles of a diameter in the range 5 .mu. to 10 .mu. are incorporated into the thickness of the wall of the shaft by adding gas during extrusion. The bubbles are selected to increase the visibility of the catheter under ultrasound imaging while still enabling material flowing along the catheter to be seen. The inventive catheter is not confined to embryo replacement catheters.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: May 2, 2017
    Assignee: The Cooper Companies Global Holdings LP
    Inventor: Stephen James Field
  • Patent number: 9592352
    Abstract: An ultrasound-guided piercing needle constituting the internal needle of an indwelling needle has ridged and grooved portions which reflect ultrasonic waves. The ridged and grooved portions comprise grooves, which are disposed on the outer periphery near the tip having a blade face, and ridges, which are arranged on both sides of the grooves.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: March 14, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Masaki Matsuzawa
  • Patent number: 9576357
    Abstract: Ultrasonic imaging methods are described for eliminating the effects of physiological motion such as respiratory motion from image data of a sequence of images which is to be used for quantified analysis such as time-intensity curve computation. A bright reflector in the images of the loop which exhibits motional effects such as cyclical variation in brightness or position from image to image is identified and its variation used to identify cycles of motion. A phase or range of phases of the cycles is identified. Images acquired during the identified phase or phase range of the motion cycles during the loop are then used for quantified processing.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: February 21, 2017
    Assignee: Koninklijke Philips N.V.
    Inventors: Michalakis Averikou, Damianos Christophides
  • Patent number: 9561017
    Abstract: The present disclosure provides for a system that is adapted to simultaneously display photoacoustic and ultrasound images of the same object. An image combiner can perform spatial and temporal interpolation of the two images before generating a combined image. The combined image is then displayed on a display such as an LCD or CRT. The system is able to use motion estimates obtained from the ultrasound data to enhance the photoacoustic image thereby increasing its apparent frame rate, registering consecutive frames in order to reduce artifacts. The system is capable of generating combined ultrasound and photoacoustic images which are registered spatially and temporally.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: February 7, 2017
    Assignee: Koninklijke Philips N.V.
    Inventor: Michael Burcher
  • Patent number: 9521993
    Abstract: A needle includes a surface with a plurality of first ultrasound reflecting depressions formed therein. The first depressions are distributed along at least a portion of a length of the needle separated from one another by intervening sections. Each of the first depressions is extending along a curve between first and second ends adjacent to corresponding ones of the intervening sections with troughs at which surfaces of each of the first depressions most closely approach a longitudinal axis of the needle being offset toward the first ends of each of the first depressions.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: December 20, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Shawn Ryan
  • Patent number: 9456806
    Abstract: A biopsy probe mechanism includes an elongate sample receiving member having a longitudinal axis and having a sample receiving notch. The elongate sample receiving member and a cutting cannula are movable relative to one another along a longitudinal axis. A first echogenic feature is established on the elongate sample receiving member and a second echogenic feature is established on the cutting cannula. The elongate sample receiving member and the cutting cannula are configured to have a first position in which the first echogenic feature is in longitudinal alignment with the second echogenic feature, and configured such that when the elongate sample receiving member and the cutting cannula are moved relative to one another from the first position, the first echogenic feature and the second echogenic feature are out of longitudinal alignment.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: October 4, 2016
    Assignee: C.R. Bard, Inc.
    Inventors: Rafal Chudzik, Jason G. Seiger, Jennifer Smith, Charles Simpson
  • Patent number: 9433373
    Abstract: The present subject matter provides apparatus and methods for physically fitting a hearing assistance device, including mathematically characterizing a person's ear canal. The apparatus includes a housing adapted to be mechanically coupled to the person in proximity to the person's outer ear. An ultrasonic transducer array is located within at least a portion of the housing. The apparatus includes electronics within the housing, the electronics adapted to control the transducer array to alternate between transmitting and receiving ultrasonic energy. In various embodiments, a processor is adapted to characterize geometry of the ear canal using information from the ultrasonic transducer array obtained from scans of the ear canal.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: September 6, 2016
    Assignee: Starkey Laboratories, Inc.
    Inventor: Thomas Howard Burns
  • Patent number: 9409001
    Abstract: A balloon catheter includes a balloon having a plurality of layers. The inner layer acts as a support layer to the outer layer. Embedded within the outer layer is a plurality of particles or pellets which in one embodiment provide roughening of the outer surface of the balloon. The particles or pellets, particularly in conjunction with an inner support layer, ensure maintenance of the roughened outer surface of the balloon during inflation of the balloon. In another embodiment, the particles or pellets may be radiopaque and/or echogenic with or without creating surface roughening of the balloon.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: August 9, 2016
    Assignee: Cook Medical Technologies LLC
    Inventors: Steen Aggerholm, Anders Scheel Klausen, Thomas Lysgaard, Anne-Mette Hoppe Sönnichsen, Allan Torp
  • Patent number: 9370338
    Abstract: Disclosed is an ultrasound diagnosis device for creating an ultrasound image with a high contrast-to-tissue ratio. Said device sends a transmission pulse to the subject, uses an ultrasound probe to receive echoes reflected from an ultrasound contrast agent injected into the subject, and forms an image. The transmission pulse is sent such that nonlinear interactions between the constituent frequency components of said transmission pulse, as a result of the acoustic nonlinearity of the subject, do not produce sum and difference components in the frequency sensitivity range of the ultrasonic probe as the transmission pulse propagates across the subject.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: June 21, 2016
    Assignee: HITACHI MEDICAL CORPORATION
    Inventors: Kunio Hashiba, Hideki Yoshikawa, Tatsuya Hayashi
  • Patent number: 9291493
    Abstract: The invention presents methods and instrumentation for measurement or imaging of a region of an object with waves of a general nature, for example electromagnetic (EM) and elastic (EL) waves, where the material parameters for wave propagation and scattering in the object depend on the wave field strength. The invention specially addresses suppression of 3rd order multiple scattering noise, referred to as pulse reverberation noise, and also suppression of linear scattering components to enhanced signal components from nonlinear scattering. The pulse reverberation noise is divided into three classes where the invention specially addresses Class I and Class II 3rd order multiple scattering that are generated from the same three scatterers, but in opposite sequence.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: March 22, 2016
    Assignee: SURF Technology AS
    Inventors: Bjørn A. J. Angelsen, Thor Andreas Tangen
  • Patent number: 9261596
    Abstract: A method for ultrasound imaging of anatomical tissue. A first signal is received from a first imaging ultrasound wave which has been reflected from a location in the anatomical tissue during a first time period. A second signal is received from a second imaging ultrasound wave which has been reflected from the location in the anatomical tissue during a later second time period, following a discrete medical treatment. The second signal is subtracted from the first signal to form a difference signal. The difference signal may be scaled, spatially filtered, then used to generate an indication, the indication showing the effect of the medical treatment in the location in the anatomical tissue.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: February 16, 2016
    Inventors: T. Douglas Mast, Waseem Faidi, Inder Raj S. Makin, Peter G. Barthe, Michael H. Slayton
  • Patent number: 9254146
    Abstract: An apparatus for performing a nerve block procedure, the apparatus being composed of an echogenic needle or an echogenic soft tissue tunneling device and an echogenic catheter configured for controlled delivery of a medication. The apparatus may further include a sheath such that at least one of the needle or tunneling device and sheath is echogenic. The present invention also encompasses a system for performing a nerve block procedure, the system includes introducing an echogenic needle in the general area of a nerve bundle, positioning the echogenic needle adjacent the nerve bundle utilizing sonic imaging techniques, introducing an echogenic catheter configured for controlled delivery of a fluid through the echogenic needle, withdrawing the echogenic needle, positioning the echogenic catheter adjacent the nerve bundle utilizing sonic imaging techniques, and delivering fluid to the nerve bundle through the echogenic catheter.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: February 9, 2016
    Assignee: Avent, Inc.
    Inventors: Roger Dillard Massengale, Steve S. Khalaj, Siddharth Desai, Dominic J. Cooke
  • Patent number: 9237883
    Abstract: A biopsy device includes coaxially disposed inner and outer needles in which the outer needle tip is configured for obtaining a tissue sample. The inner surface of the outer needle includes a tissue retention feature which may include a countersink and/or a feature formed in the inner surface. The device may be configured such that the inner needle does not extend past a certain point within the outer needle.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: January 19, 2016
    Assignee: JJ Dogs LLC
    Inventors: Herbert Alan Sundheimer, Dan C. Ireland
  • Patent number: 9232478
    Abstract: A method, an apparatus, and a computer program product for wireless communication are provided in which a set of time intervals is obtained from a received radio frequency signal. A power profile is determined for a frequency spectrum segment in each time interval. A first list is used to identify frequency spectrum segments that exhibit a power or energy profile over a range of frequencies associated with a downlink channel bandwidth, and a second list is used to identify frequency spectrum segments that have a total or average energy greater than a threshold energy relative to a noise floor. An absolute radio frequency channel number (ARFCN) of a wireless communication system is determined based on the time intervals identified in the first and second lists.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: January 5, 2016
    Assignee: QUALCOMM Incorporated
    Inventors: Huilin Xu, Raghu Narayan Challa, Hisham A. Mahmoud
  • Patent number: 9226683
    Abstract: Scan timing of contrast agent study is provided. Ultrasound is used to determine timing of contrast agent inflow and/or outflow. The timing based on the ultrasound scanning controls scanning for MR or CT imaging. The MR or CT contrast agent imaging for MR or CT contrast agents may be synchronized using the ultrasound contrast agent flow.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: January 5, 2016
    Assignees: Siemens Medical Solutions USA, Inc., Siemens Aktiengesellschaft
    Inventors: Patrick Gross, Caroline Maleke, Stephen J. Hsu, Chi-Yin Lee, Jerry Hopple, Xiaozheng Jenny Zeng
  • Patent number: 9192303
    Abstract: Aspects of the disclosure relate to fluorescence imaging, and more particularly to the use of temperature modulation in a tissue site with a modulator such as high intensity focused ultrasound to modulate the emission signal emitted by temperature-sensitive optical fluorescence reporters.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: November 24, 2015
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Gultekin Gulsen, Yuting Lin
  • Patent number: 9192354
    Abstract: An ultrasound diagnostic apparatus comprising: an image forming unit which forms an ultrasound image that corresponds to an echo signal received from a subject to which a contrast medium has been administered; a region of interest setting unit which sets, in a target region corresponding to target tissue on the ultrasound image formed by the image forming unit, a first region of interest and a second region of interest which are two regions different from each other; a feature value extraction unit which extracts, as a feature value, a difference in brightness between the first region of interest and the second region of interest set by the region of interest setting unit; and a type determination unit which determines, based on the feature value extracted by the feature value extraction unit, a type of the target tissue.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: November 24, 2015
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kazuya Takagi, Satoshi Kondo
  • Patent number: 9153046
    Abstract: A sectional image and a two-dimensional elasticity image on an arbitrary cross section are added at a first combination ratio received from an operator to produce an arbitrary cross-section combined image. A three-dimensional image and a three-dimensional elasticity image of a predetermined part are added at a second combination ratio received from the operator to produce a three-dimensional combined image. The arbitrary cross-section combined image and the three-dimensional combined image are displayed side by side in a display. This can provide an ultrasonic diagnostic apparatus capable of facilitating the grasp of the structure and the recognition of the hardness of the living organ within the object from the plurality of images.
    Type: Grant
    Filed: September 11, 2011
    Date of Patent: October 6, 2015
    Assignee: HITACHI MEDICAL CORPORATION
    Inventor: Yuki Sawayama
  • Patent number: 9131923
    Abstract: An ultrasonic diagnostic device and image display method display an inflow time map representing relative differences in blood flow dynamics such as inflow of a contrast agent, including extracting a vessel and constructing a noise-less inflow time map, and, in the comparison of differences in color between the constructed inflow time map and the past inflow time map, unifying the color of regions as a base. A TIC analysis unit calculates a parameter (t?) indicating an inflow starting time of a contrast agent and a difference of brightness ?I due to the contrast agent using image data in a range designated by an image detection unit. A first pixel selection unit extracts a pixel and removes a non-contrast-enhanced region. An image construction unit constructs an inflow time map colored according to t?, and a second pixel selection unit extracts a vessel using a histogram based on ?I.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: September 15, 2015
    Assignee: HITACHI MEDICAL CORPORATION
    Inventor: Hideki Yoshikawa
  • Patent number: 9113990
    Abstract: An implant includes a substrate and a carrier coupled to the substrate. The carrier including a plurality of objects configured to reflect energy emitted by an ultrasound device. In some embodiments, the carrier includes a plurality of air bubbles that are configured to reflect energy emitted by an ultrasound device. In one embodiment, a method of forming a bodily implant includes forming a substrate, disposing a plurality of air bubbles within a carrier, and applying the carrier to the substrate.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: August 25, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Isaac Ostrovsky, Jianmin Li, Tim Harrah, Jozef Slanda
  • Patent number: 9095313
    Abstract: Apparatus and methods are provided including, while an endoluminal data-acquisition device is being moved through a lumen of a subject, acquiring a plurality of endoluminal data points of the lumen using the endoluminal data-acquisition device. At at least one location it is determined that an event occurred, the event causing the endoluminal data-acquisition device not to acquire a single endoluminal data point at the location. The endoluminal data points are displayed in a stack, in which the endoluminal data points are positioned at locations corresponding to relative locations within the lumen at which the endoluminal data points were acquired, and in which the event is accounted for. Other applications are also described.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: August 4, 2015
    Assignee: SYNC-RX, LTD.
    Inventors: David Tolkowsky, Ran Cohen, Eldad Klaiman, Alexander Steinberg, Zohar Barzelay
  • Patent number: 9066674
    Abstract: Destruction for reperfusion in medical diagnostic ultrasound is synchronized to motion. Perfusion data for a volume is acquired sequentially for different segments of the volume. For a given segment, such as a planar region, motion tracking within the segment is performed. If sufficient registration or correlation exists at the completion of a sequence of scans for the current segment, then a lesser amount of movement is occurring. At this point, the transmission of contrast agent destructive acoustic energy is performed in the next segment. Tracking is repeated for the next segment to synchronize the switch to yet another segment. Other regions for tracking can be used. By controlling transmission of destruction pulses, more reliable perfusion quantities in a volume may be determined.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: June 30, 2015
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventor: Ismayil M. Guracar
  • Publication number: 20150141833
    Abstract: An imaging catheter system is provided, including a hollow lumen having a distal portion, and a plurality of first transducer elements arranged in a first array configured to be received within the distal portion of the hollow lumen. Each of the first transducer elements include a micromachined piezocomposite, and the plurality of first transducer elements is configured to operate at an effective operational frequency of greater than about 30 MHz. A plurality of second transducer elements configured to operate at an effective operational frequency of less than about 15 MHz may be arranged in a second array, each of the second transducer elements including a micromachined piezocomposite, and engaged with the first array. The low frequency array may be operated in a transmit mode and the high frequency array may be operated in a receive mode to facilitate contrast imaging.
    Type: Application
    Filed: May 29, 2013
    Publication date: May 21, 2015
    Inventors: Paul Dayton, Xiaoning Jiang
  • Patent number: 9037218
    Abstract: Electromagnetic energy is applied to thereby oscillate a bubble that is then insonified to produce an echo (260) for reception and analysis to afford imaging of the region of the bubble. To create the bubble, the energy may be applied to a nano particle (232) of a contrast agent whose consequent internal nano- or micro-bubbles offer, with novel pulsing techniques, greater sensitivity, and which can permeate outside vasculature (216) prior to being energized thereby affording quantification of vascular permeability and delivery of targeting molecules. The particle can include an absorbing and an evaporating parts, the irradiation (204), as by near-infrared laser, causing the phase change that gives rise to the bubble. The echo may occur in response to ultrasound interrogation (220) of the activated contrast agent, which could entail pulse inversion, power modulation or contrast pulse sequence imaging, with persistence processing.
    Type: Grant
    Filed: October 11, 2010
    Date of Patent: May 19, 2015
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Yao Wang, William Tao Shi
  • Patent number: 9022939
    Abstract: Method and system for ultrasound imaging of body tissue in which a focused ultrasound (FUS) transducer (20) is oriented relative to the body such that ultrasonic waves generated by the FUS transducer (20) are directed toward the tissue being imaged. The FUS transducer (20) is operated to cause the formation of microbubbles (28) in the tissue and an ultrasound image of the tissue with the microbubbles (28) is acquired. Phase aberration in the acquired ultrasound image may be corrected, if necessary, using each microbubble (28) as a point source or point-like scatterer. Microbubble (28) formation can therefore be obtained in a non-invasive manner since FUS-induced microbubble (28) formation does not require the insertion of interventional tools into the body.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: May 5, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Christopher Hall, Shunmugavelu Sokka, David Louis Marie Savery, Chien-Ting Chin
  • Patent number: 9005128
    Abstract: An imaging part acquires a plurality of ultrasound image data by sequentially imaging the subject with ultrasound waves. A display controller causes a display to display, side by side, a plurality of ultrasound images based on the plurality of ultrasound image data acquired by the imaging part. Moreover, the display controller causes the display to display measurement markers for obtaining quantitative information of tissues shown in the ultrasound images in a state superimposed in relatively the same positions on the plurality of ultrasound images.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: April 14, 2015
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems Corporation
    Inventors: Tomohisa Imamura, Kazuya Akaki, Atsushi Sumi, Akihiro Kakee, Takuya Sasaki
  • Patent number: 8965486
    Abstract: The invention provides materials, devices and methods for marking biopsy sites for a limited time. The biopsy-marking materials are ultrasound-detectable bio-resorbable powders, with powder particles typically between about 20 microns and about 800 microns in maximum dimension, more preferably between about 300 microns and about 500 microns. The powders may be formed of polymeric materials containing cavities sized between about 10 microns and about 500 microns, and may also contain binding agents, anesthetic agents, hemostatic agents, and radiopaque markers. Devices for delivering the powders include tubes configured to contain the powders and to fit within a biopsy cannula, the powders being ejected by action of a syringe. Systems may include a tube containing powder, and a syringe containing sterile saline. The tube may be configured to fit within a biopsy cannula such as a Mammotome® or SenoCor 360™ cannula.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: February 24, 2015
    Assignee: SenoRx, Inc.
    Inventors: Fred H. Burbank, Paul Lubock, Michael L. Jones
  • Patent number: 8956301
    Abstract: Frame rate and/or line density are controlled in contrast agent medical diagnostic ultrasound imaging. The number of lines scanned per second (e.g., frame rate and/or line density) is set based on the differences in contrast agent response. Where the contrast agent response is changing rapidly, more frequent scanning and/or denser scanning is performed. Where the contrast agent response is not changing or changing slowly, less frequent scanning and/or less dense scanning is performed. By linking the number of scan lines per second of the scanning adaptively with the contrast agent response, the destruction of contrast agents may be reduced while providing information when needed for diagnosis.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: February 17, 2015
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventor: Roee Lazebnik
  • Patent number: 8939910
    Abstract: A hydrogel marker is placed under stress during its curing stage, in one embodiment, by application of an externally applied force. The stress may also be induced during or after the dehydration process. The direction of the externally applied force increases the length, width, depth, or radial extent of the marker. The elastic limit of the marker is exceeded when the external force is applied so that the marker substantially retains its stressed size and shape when the externally applied force is removed. When the stretched or otherwise deformed dehydrated marker is hydrated, it substantially returns to the configuration it had prior to its dehydration and prior to the application of the externally applied force.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: January 27, 2015
    Assignee: Devicor Medical Products, Inc.
    Inventor: John S. Fisher
  • Patent number: 8926516
    Abstract: An ultrasound imaging apparatus comprises an ultrasonic probe configured to transmit and receive an ultrasonic wave and a controller configured to control the ultrasonic probe such that an ultrasonic wave for imaging a contrast agent injected into an object and an ultrasonic wave for imaging a tissue movement of the object are transmitted in time division. A method of ultrasound imaging comprises transmitting a first ultrasonic wave and a second ultrasonic wave which hardly destroys bubbles of a contrast agent, obtaining blood flow information based on a signal generated from the first ultrasonic wave, and obtaining tissue movement information based on a signal generated from the second ultrasonic wave.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: January 6, 2015
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems Corporation
    Inventor: Hiroyuki Tsujino
  • Patent number: 8923953
    Abstract: A medical examination apparatus including a control unit, an image-generating modality and a controllable injection apparatus for a contrast agent is provided. The control unit is connected to an alarm signal emitter and the control unit switches the modality and the injection apparatus to a safe mode as a function of an alarm signal.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: December 30, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Stefan Assman, Björn Heismann, Reto Merges, Markus Schmidt, Sebastian Schmidt, Kera Westphal
  • Publication number: 20140378841
    Abstract: The present invention provides an article or an interface having a distribution of a first partially spherical indentation and at least a second partially spherical indentation contained within the first indentation to form a multi-component or “compound” shape that is referred to as a “compound” or “nested” dimples or indentations. These compound dimples or indentions may be concentric and are etched or otherwise formed into a surface or interface of an article to enhance the ultrasonic imaging. Exemplary articles may be needles of the type used to conduct nerve blocks or the interface may be the surface of such a needle, cannula, catheter, catheter tip or similar article.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 25, 2014
    Inventors: Alfred C. Coats, Louis Lupin
  • Patent number: 8917925
    Abstract: Systems and methods are disclosed for image reconstruction and enhancement, using a computer system. One method includes acquiring a plurality of images associated with a target anatomy; determining, using a processor, one or more associations between subdivisions of localized anatomy of the target anatomy identified from the plurality of images, and local image regions identified from the plurality of images; performing an initial image reconstruction based on image acquisition information of the target anatomy; and updating the initial image reconstruction or generating a new image reconstruction based on the image acquisition information and the one or more determined associations.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: December 23, 2014
    Assignee: HeartFlow, Inc.
    Inventors: Leo Grady, Michiel Schaap
  • Patent number: 8911372
    Abstract: A diagnostic imaging apparatus for imaging information changing with time and displaying it in real time, composed of an ultrasonic probe (2), having piezoelectric elements arranged in an array form that transmit ultrasonic waves to a target object (1) and acquires a reflection signal from the target object; a body movement measuring unit (12) that constitutes a two-dimensional ultrasonic image using the reflection signal acquired by the ultrasonic probe, sets, in the image plane, a plurality of measuring areas used for measuring the body movement of the target object, and measures the body movement and deformation amounts in the measuring areas; and an image accumulating (subtracting) unit for accumulating or subtracting images using body movement measured by the body movement measurement unit.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: December 16, 2014
    Assignee: Hitachi Medical Corporation
    Inventors: Hideki Yoshikawa, Takashi Azuma, Kenichi Kawabata, Kazuaki Sasaki, Shinichiro Umemura