Abstract: A device for imaging within a body of a patient is provided. In one embodiment, the device includes a flexible elongate member that can be inserted into the body of the patient. The device also has an imaging assembly that is disposed at and extending a length of a distal portion of the flexible elongate member. The imaging assembly may include an array of imaging elements that may have an outward surface and an inward surface. The imaging assembly may further include an integrated circuit adjacent to the inward surface of the array of imaging elements. The device may further include a conductive plate adjacent to and extending at least a portion of a length of the imaging assembly. The conductive plate may receive heat generated by at least one of the array of imaging elements or the integrated circuit.

Abstract: A system configured to control an endoscope probe either in manual mode or in robotic mode. The system comprises: a handle at a proximal end of the probe; a handheld controller attachable to the handle; and a robotic controller in communication with the handle and/or the handheld controller. The handheld controller includes separate controls for the manual and robotic modes. In manual mode, the handheld controller combined with the handle and the probe is used to manually control insertion and actuation of the probe into a first location of a lumen. In robotic mode, the handheld controller is removed from the handle, and the robotic controller controls handle to robotically navigate the probe to a second location within the lumen. Attachment and detachment of handheld controller to the handle is such that only certain controls appropriate to a particular portion of a workflow are accessible to the user.

Abstract: A tethered laparoscopic probe for deployment through a trocar into a cavity of a subject and manipulatable by fenestrated laparoscopic graspers includes opposing fenestrated jaws. The tethered laparoscopic probe also includes a probe head shaped for insertion through the trocar and including an elongated casing, a sensor arranged within the casing and defining a sensing direction of the probe head, and a grip for secure grasping by the fenestrated laparoscopic graspers. The grip has protrusions for mating with the fenestrated jaws. The tethered laparoscopic probe further includes a tether coupled to the probe head. The protrusions are positioned and shaped to enable the grip to be grasped securely by the fenestrated laparoscopic graspers at a first angle relative to the sensing direction of the probe head and at a second angle relative to the sensing direction of the probe head, the second angle being different from the first angle.

Abstract: An endoscope including: a retaining body; and a flexible printed circuit board providing an electrical connection between an electrical component arranged in a proximal end region of the endoscope and an internal electrical terminal provided in the proximal end region distanced along a longitudinal axis from the electrical component. The flexible printed circuit board includes: a first circuit board section extending in a longitudinal axial direction and guided at least partially in a cavity in the endoscope by the electrical terminal in the direction of the electrical component, and a second circuit board section arranged on the retaining body and guided along a lower side of the retaining body directed in a direction of an internal space in the endoscope and along an upper side of the retaining body directed in a direction of an outer sleeve of the endoscope towards the electrical component, and electrically contacts the electrical component.

Abstract: A sensor guide wire for intravascular measurement of a physiological variable includes: a core wire extending at least partly along a length of the sensor guide wire; a sensor element in a sensor region of the sensor guide wire; a jacket having a jacket wall, the jacket being fixed relative to the core wire; and at least one lead connected to the sensor element. The jacket is tubular and includes a proximal end opening, a distal end opening, and a first set of openings extending through the jacket wall. The first set of openings extending through the jacket wall includes a first opening located above the sensor element, a second opening located at a first lateral side of the sensor element, and a third opening located at a second lateral side of the sensor element, and wherein the first, second, and third openings are elongated in a longitudinal direction of the jacket, and are aligned in a circumferential direction of the jacket.

Abstract: A controller (120) for simultaneously tracking multiple sensors in a medical intervention includes a circuit (121-181) that causes the controller (120) to execute a process. The process executed by the circuit (121-181) includes receiving first and second signals respectively from a first and a second passive ultrasound sensor (S2) used in the medical intervention. The first and second signals respectively include first and second sensor information indicative of respective locations of the first and the second passive ultrasound sensor (S2). The process executed by the circuit (121-181) also includes combining (120) the first signal and the second signal for transmission over only one channel, and providing the first signal and the second signal over the only one channel to a system (190) that determines the location of the first passive ultrasound sensor (S1) and the location of the second passive ultrasound sensor (S2) and that has only the one channel to receive the first signal and the second signal.

Abstract: A capacitive micro-machined ultrasonic transducer (CMUT) device in which integrated probe circuitry includes both the ultrasound transmission and reception circuitry and a DC-DC converter for generating a bias voltage for the CMUT cell. The high voltage pulses of a pulser circuit and a high voltage DC bias voltage are both generated by a single probe circuit, which is local to the CMUT cell.

Abstract: Provided is an ultrasound bronchoscope capable of preventing a non-coaxial cable from being disconnected and improving a degree of freedom of wirings. An ultrasound bronchoscope includes a distal end part having an ultrasound transducer array, a bending part that is coupled to a proximal end of the distal end part and is bendable in two directions, a flexible part that is coupled to a proximal end of the bending part, a cable that is inserted into the flexible part and the bending part, and a flexible substrate that electrically connects a plurality of ultrasound transducers and the cable, and is disposed over the distal end part, the bending part, and a part of the flexible part.

Abstract: A method includes, in a medical procedure carried out during a time interval including at least first and second time periods, receiving, for the first time period, a first electrical signal indicative of at least a first position and a first orientation of a hand-held device directing energy to one or more volumetric portions of an organ. A second electrical signal indicative of at least a second position and a second orientation of the hand-held device is received for the second time period. Based on the first and second electrical signals, a cumulative energy applied to at least one of the one or more volumetric portions is estimated. The estimated cumulative energy, of at least one of the one or more volumetric portions, is overlaid on an anatomical image of the organ.

Abstract: The present invention relates to an ultrasound system. A first non-invasive ultrasound probe receives first ultrasound data having a first field of view and a second invasive ultrasound probe receives second ultrasound data having a second field of view which is different from the first field of view. A tracking unit determines tracking data including a position and orientation of the first non-invasive ultrasound probe relative to the second invasive ultrasound probe. A registration unit registers the second field of view into the first field of view based on the tracking data.

Abstract: A variety of medical and non-medical devices are exploited by users to address a wide range of conditions. However, in the vast majority of instances, the device has a limited number of options with respect to its fit for the user and its performance. Further, the determination of target performance and fit are established on a qualitative basis rather than a quantitative basis. In many instances, these combinations lead to low user acceptance of the device due to the resulting performance and fit issues. Accordingly, it would enhance performance and user acceptance if a quantitative determination provided a recommended type where options exist, and this determination provided the basis of a custom designed device to the user's specific anatomical and/or performance requirements.

Abstract: An optical tissue imaging system includes a probe for insertion into a transparent cylindrical capillary. The capillary includes an internal cylindrical channel that extends along a central axis. The capillary is inserted into tissue of a subject, and the probe may rotate and translate within the capillary. The probe may include a mirror configured to reflect light to the tissue outside of the cylindrical capillary.

Abstract: A sensor guide wire includes a sensor element arranged in a jacket in a sensor region of the sensor guide wire; a core wire extending at least partly along a length of the sensor guide wire; and at least one electrical lead connected to the sensor element. The jacket is tubular and includes proximal and distal end openings, a jacket wall, a first opening arranged in the jacket wall, and a second opening arranged in the jacket wall, the first and second openings being proximate to the sensor element. The core wire is adapted to extend through the jacket via the proximal and distal end openings. At least a portion of the first opening and at least a portion of the second opening are both located in the same cross-section of the sensor guide wire, the cross-section being perpendicular to the longitudinal axis of the sensor guide wire.

Abstract: The invention relates to a computer-implemented medical method for determining a virtual flight-path (1) with respect to a virtual representation (2) of at least one anatomical structure, the method comprising executing, on a processor of a computer, the steps of:—acquiring, on the processor, patient image data describing at least one patient image showing at least one anatomical structure of a patient; —acquiring, on the processor, atlas data describing at least one model of the at least one anatomical structure; —determining, by the processor and based on the patient image data and the atlas data, representation data describing a virtual representation of the at least one anatomical structure; —acquiring, on the processor, requirement data describing at least one requirement for at least one flight-path (1); and—determining, by the processor and based on the representation data and the requirement data, flight-path data describing at least one virtual flight-path (1) with respect to the virtual representati

Abstract: Ultrasonic force detection systems and methods can be based on propagation of ultrasonic waves in a user's body (e.g., in a user's digit). An amount of force can be determined using time-of-flight (TOF) techniques of one or more ultrasonic waves propagating in the user's body. In some examples, an electronic device including a transducer can be coupled to a digit, and can transmit ultrasonic waves into the digit. As the wave propagates through the thickness of the digit, a reflection of at least a portion of the transmitted wave can occur due to the bone and/or due to reaching the opposite side of the digit (e.g., finger pad). One or more reflections can be measured to determine the amount of force.

Abstract: A surgical stapling device includes a body portion that defines a longitudinal axis and a tool assembly that articulates about an axis transverse to the longitudinal axis. The surgical stapling device includes an articulation member that is supported in the body portion and is movable between retracted and advanced positions to pivot the tool assembly between a non-articulated position and articulated positions. The body portion supports a braking assembly that moves into engagement with the articulation member to stabilize the articulation member when the surgical stapling device is fired.

Abstract: An apparatus includes an elongate member having proximal and distal portions; a rotatable drive cable disposed within the elongate member, the drive cable being connectable to a mechanism to which torque can be applied; and a control assembly mechanically coupled to the drive cable, and configured to disengage the mechanism from the drive cable when the applied torque exceeds a predetermined level, wherein disengagement of the mechanism from the drive cable causes rotation of the drive cable to stop or withdrawal of the drive cable.

Abstract: An infusion system determines a volumetric flow rate of infusion fluid delivered by an infusion pump along a flow path based on: an upstream acoustic signal emitted by at least one upstream acoustic sensor and detected by at least one downstream acoustic sensor; a downstream acoustic signal emitted by the downstream acoustic signal and detected by the upstream acoustic sensor; and a phase delay between the upstream acoustic signal and the downstream acoustic signal either upstream or downstream. The infusion system automatically adjusts the infusion pump based on the determined volumetric flow rate to achieve a desired volumetric flow rate of the infusion fluid along the flow path.

Abstract: A robotic catheter procedure system includes a bedside system that has a percutaneous device, and an actuating mechanism configured to engage and to impart movement to the percutaneous device. The system also includes a workstation coupled to the bedside system. The workstation includes a user interface configured to receive a user input, ma display device configured to display an image, a control system operatively coupled to the user interface and the actuating mechanism. The control system is configured to generate a control signal and the actuating mechanism causes movement of the percutaneous device in response to the control signal. The control system is configured to slow movement of the percutaneous device via the actuating mechanism as an identified point on the percutaneous device approaches a structure requiring a change in direction of the percutaneous device.

Abstract: A steerable medical apparatus includes a shaft, a steering mechanism, and an actuation mechanism. The shaft has a proximal portion, a distal portion, a first pull wire, and a second pull wire. The distal ends of the first and second pull wires are coupled to the distal portion of the shaft. The steering mechanism has a first wheel and a second wheel coupled by a differential mechanism. The proximal ends of the first and second pull wires are respectively coupled to the first and second wheels. The actuation mechanism is coupled to the steering mechanism. Actuating the actuation mechanism in a first operational mode causes the distal portion of the shaft to curve in a first plane. Actuating the actuation mechanism in a second operational mode causes the distal portion of the shaft to curve away from the first plane.

Abstract: The invention relates to an ultrasound system (100) for sequentially performing a predetermined procedure for each of at least one region of interest. The ultrasound system (100) comprises an ultrasound probe (101) configured to transmit a first ultrasound signal (SG1) towards a region of interest and receive echo signals from the region of interest. The ultrasound system (100) also comprises a motion sensor (102) configured to detect a motion of the ultrasound probe (101) and generate a motion signal (MS) for indicating the motion of the ultrasound probe (101). The ultrasound system (100) also comprises a processor (103) configured to perform a predetermined procedure for a region of interest on the basis of the echo signals received from the region of interest if the motion signal (MS) indicates that the ultrasound probe (101) is stationary. The invention also relates to a corresponding ultrasound method.

Abstract: An x-axis curvable LED strip includes an elongated curved channel having a bottom portion and one or more walls extending therefrom; an elongated lens to secure over a top of the elongated curved channel; and a flexible light strip, having a mounting strip to secure to one of the one or more walls of the elongated curved channel; LED lights attached to the mounting strip by an extension such that the LED lights are positioned within the elongated curved channel along the bottom portion; the LED lights emit light through the elongated lens.

Abstract: An ultrasonic endoscope has an ultrasonic vibrator array in which a plurality of ultrasonic vibrators are arrayed; a backing material layer that supports the ultrasonic vibrators; shield cables that each include a signal wire and a shield member for the signal wire; a flexible printed wiring board that extends on a side opposite to the ultrasonic vibrator array with respect to the backing material layer and that includes a ground portion electrically connected to the shield members; and a heat conductive layer that is provided on at least one surface of the flexible printed wiring board and connected to the ground portion, the heat conductive layer dissipating heat generated in the plurality of ultrasonic vibrators to the ground portion.

Abstract: An endoscope includes: an insertion portion to be inserted into a subject; an image sensor provided at a distal end of the insertion portion and configured to acquire an image of the subject; a signal cable connected to the image sensor at one end of the signal cable, the signal cable including a signal line group formed of a plurality of signal lines configured to transmit signals acquired by the image sensor; a tube provided at a part of the signal cable, the tube covering the signal cable and having insulation properties; and a filling member configured to fill a vacant space formed between the signal cable and the tube and at least a part of which is made of a material with low melting point.

Abstract: An ultrasonic endoscope has a laminated body that includes an ultrasonic transducer array in which a plurality of ultrasonic transducers are arranged, and a backing material layer that supports the plurality of ultrasonic transducers; a cable portion that includes a plurality of cables each of which is electrically connected to a corresponding one of the plurality of ultrasonic transducers, and a shield member that covers the plurality of cables from outside and that is made of a metal; and a first heat conductive member that is disposed on a side surface of the laminated body. The first heat conductive member is extended to the shield member that is grounded to a housing and is thermally connected to the shield member.

Abstract: A method of manufacturing an endoscope includes: dividing some of signal lines into bundle portions; notching a part of a tube to form one or a plurality of notch portions; cutting at least one end portion of the tube in a state where the tube is folded with each notch portion to produce a first heat-shrinkable tube having cylindrical portions with aligned end portions in longitudinal directions of the cylindrical portions; inserting the divided bundle portions into the cylindrical portions of the first heat-shrinkable tube, respectively; inserting the signal lines into a second heat-shrinkable tube; heating at least an overlapping portion in a state where the first and second heat-shrinkable tubes partially overlap each other to cause heat shrinkage; inserting the signal cable and the channel into a tubular portion; and connecting the tubular portion to a distal end constituting portion to form the insertion portion.

Abstract: An ultrasonic endoscope has an ultrasonic transducer array in which a plurality of ultrasonic transducers are arranged; a backing material layer on a back side of a plurality of ultrasonic transducers, a wiring board including a plurality of electrode pads that are connected to the plurality of ultrasonic transducers; a plurality of shield cables each including a signal wire and a shield member, a wiring portion in which the plurality of signal wires are electrically connected to the plurality of electrode pads; a ground portion that is electrically connected to the shield members and that have heat conductivity; and a first heat conductive member that extends beyond the backing material layer to a side opposite to the ultrasonic transducer array with respect to the backing material layer and that is thermally connected to the ground portion.

Abstract: An esophageal monitoring device includes a camera and, optionally, one or more lights to enable visualization of an interior of a subject's esophagus. Visualization of the interior of the subject's esophagus before and after a left atrial ablation procedure may enable a healthcare provider to determine whether or not the left atrial ablation procedure has damaged the subject's esophagus before the subject experiences any symptoms of such damage. An esophageal monitoring device may also include sensors and/or markers that enable a determination of its location within a subject's esophagus. Such an esophageal monitoring device may be configured for three-dimensional mapping, and enable the generation of an accurate three-dimensional map of the physical relationship between a subject's esophagus and the left atrium of his or her heart. Methods of monitoring a subject's esophagus while a left atrial ablation procedure is being conducted on the subject's heart are also disclosed.

Abstract: An encapsulated integrated circuit is provided that includes an integrated circuit (IC) die. A phonon device is fabricated on the IC die that is configured to emit or to receive phonons that have a range of ultrasonic frequencies. An encapsulation material encapsulates the IC die. A phononic bandgap structure is included within the encapsulation material that is configured to have a phononic bandgap with a frequency range that includes at least a portion of the range of ultrasonic frequencies. A phononic channel is located in the phononic bandgap structure between the phonon device and a surface of the encapsulated IC.

Abstract: Certain embodiments provide a hearing testing probe apparatus. The hearing testing probe apparatus includes a probe tube detachably coupled at a first end to a probe body and extending through a center hole in an eartip to align proximate a face of the eartip at a second end. The probe tube includes a plurality of stimulus lumens for receiving and carrying stimulus from the first end of the probe tube for output at the second end of the probe tube. The probe tube includes one or more microphone lumens for receiving and carrying one or more measured responses from the second end of the probe tube to one or more microphones at the first end of the probe tube.

Abstract: An endoscope or exoscope having a shaft and at least one objective and at least one electronic image recorder for recording an image of an object field, wherein the objective and image recorder are arranged in a distal end region of the endoscope or exoscope, and includes at least one cable, routed within the endoscope or exoscope, for supply of and/or image transmission from the electronic image recorder, wherein the electronic image recorder includes an optical unit, which is rotatable about a first axis of rotation identical or approximately parallel to a direction of view of the scope, and on which the cable is connected and can be wound on a circumferential surface of the optical unit, and wherein the distal end region includes a cavity, in which storage for holding a section of the cable is held.

Abstract: An ultrasound probe and method of forming an ultrasound probe are provided. The ultrasound probe comprises a two-dimensional (2D) transducer assembly having transducer elements arranged in rows and columns. The transducer elements have front and rear surfaces. The front surface is configured to transmit and receive ultrasound signals to and from an object of interest. A thin film flex circuit extends along the rear surface of the transducer assembly. The flex circuit has conductive traces arranged in layers and enclosed within a common dielectric layer. The dielectric layer has a homogeneous composition surrounding the layers of the conductive traces. The conductive traces are electrically interconnected to the corresponding transducer elements.

Abstract: A device includes a catheter section comprising a flexible joint region disposed between a distal end and a proximal end. The device includes a laser fiber disposed within the catheter section. The laser fiber emits laser light at a fiber distal end. The device includes a wire comprising a distal end coupled to the catheter section. The wire is configured to move the distal end of the catheter section from a first position to a second position about the flexible joint region.

Abstract: Renal failure therapy system includes a blood filter, a blood pump, a dialysis fluid pump, a blood line connecting to a patient, a transmitter for receiving a transmit signal and transmitting a wave into blood flowing through the blood line, a receiver for receiving the wave and emitting a corresponding received signal, and a processor for initiating the transmit signal and for receiving the received signal, configured to convert the transmit and received signals into a frequency domain, extract spectral values for the converted transmit and received signals, calculate at least one of a reflection coefficient (R) or an impedance ratio (I) using the spectral values, and analyze an imaginary part of at least one of R or I to determine if an access disconnection event concerning fluid communication between the blood line and the patient has occurred.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to heat tissue to create lesions without ablating the tissue. The system includes a first treatment device having at least one electrode for applying radiofrequency energy to tissue, a controller including a connector to which a first treatment device is coupled for use, and a generator for applying radiofrequency energy to the electrodes. The controller controls application of energy so that the tissue is thermally treated to create lesions but preventing thermal treatment beyond a threshold which would ablate the tissue.

Abstract: An implant sized and shaped to be endovascularly delivered to the middle meningeal artery includes a carrier that carries a payload between first and second ends thereof. An anchor mechanism associated with the implant transitions into a swollen state in response to exposure to bodily fluids. In the swollen state, said anchor mechanism anchors the implant to the middle meningeal artery. Before or during the transition, the anchor mechanism permits endovascular delivery of the implant to the middle meningeal artery.

Abstract: The invention proposes to detect and track an intervention device in a 2D fluoroscopy image and to steer an ultrasound probe beam towards this device. Therefore, a method and corresponding system is proposed, by which an ultrasound probe is registered in a fluoroscopy image, wherein the registering includes the estimation of the position and of the orientation of the probe relative to the fluoroscopy.

Abstract: A device includes a first retainer plate, a second retainer plate, a connector link, and a clamp. The second retainer plate has a clearance aperture. The connector link has a first end and a second end. The first retainer plate is coupled to the first end and the second retainer plate is coupled to the second end. The first retainer plate and second retainer plate are in parallel alignment. At least one of the first retainer plate and the second retainer plate are elastically urged to converge. The clamp is coupled to the connector link by a joint. The joint is configured to articulate in at least two degrees of freedom and configured to retain a selected fixed alignment as to the connector link relative to the clamp.

Abstract: An embodiment of a fluid infusion device includes a fluid pump mechanism having a rotor and a stator. The rotor includes a reference surface and a cam element rising from the reference surface, and the stator includes a cam element having a stator cam surface. The cam elements cooperate to axially displace the rotor as a function of angular position of the rotor. A biasing element provides force to urge the cam elements together. A drive motor actuates the rotor to pump medication fluid from a fluid cartridge module to a body, via a subcutaneous conduit. A detection circuit processes axial and angular position data of the rotor, and determines that an upstream occlusion has occurred based on detectable characteristics of the axial and angular position data.

Abstract: Assemblies are provided for positioning within a lumen comprising a stent graft; and a sensor positioned on the stent graft. Within certain aspects the sensors are wireless sensors, and include for example one or more fluid pressure sensors, contact sensors, position sensors, pulse pressure sensors, blood volume sensors, blood flow sensors, chemistry sensors (e.g., for blood and/or other fluids), metabolic sensors (e.g., for blood and/or other fluids), mechanical stress sensors and/or temperature sensors.

Abstract: Registration is provided for imaging with an intra-patient probe. The intra-patient probe is used for imaging or the imaging is, at least in part, of the intra-patient probe. Either approach for imaging with an intra-patient probe uses active transitions for registration. In one embodiment, one or more markers in the intra-patient probe are moveable relative to the intra-patient probe, allowing avoidance of occlusions and providing more reliable marker detection for registration. In another embodiment, a value of a parameter for imaging with at least one modality is changed so that acceptable or better registration with an image of another modality may be made. The imaging is repeated with differences, such as field-of-view or scale, allowing for registration for different types of modalities.

Abstract: A system for identifying an attribute of an implanted medical device, such as an access port is disclosed. In one embodiment, the identification system comprises a marker included with the implanted medical device, wherein the marker relates to an attribute of the implanted medical device. An external detection device is also included, comprising a signal source that emits an incident electromagnetic signal for impingement on the marker of the implanted medical device, a detector that detects a return signal from the marker resulting from impingement of the incident electromagnetic signal, and a user interface for conveying information relating to the attribute based on detection of the return signal. In the case of an implantable access port, for instance, the described system enables information, such as the ability of the port to withstand power injection of fluids therethrough, to be ascertained even after the port has been subcutaneously implanted within the patient.

Abstract: A device is for thermal treatment of tissue. The device includes (a) an elongated member extending from a proximal end to a distal end insertable to a target position within a body; (b) a housing coupled to the distal end of the elongated member sized and shaped for insertion to a target organ within a living body, the housing including an opening permitting fluid surrounding the housing to enter the housing, the housing further including first and second deflecting elements shaped to diffuse pulses of fluid directed thereagainst; and © a piezoelectric element mounted within the housing between the first and second deflecting elements. The piezoelectric element is oriented to generate pulses in liquid received within the housing toward the first and second deflecting elements.

Abstract: A medical device is used to image a body cavity using a plurality of axially and angularly spaced imaging sensors. Each imaging sensor generates an image that is distinct from one another due to distinct fields of vision. Each image includes an overlapping zone with commonalties that are used to extrapolate a greater calibrated image.

Abstract: Stent delivery system comprising a catheter shaft having a proximal end portion and a distal end portion and an expandable member provided at the distal end portion of the shaft, the expandable member having a delivery condition and a deployed condition and formed at least in part from a matrix of fiber elements to define a continuous surface substantially free of openings when in the delivery condition.

Abstract: A modular handle assembly for supporting and controlling a steerable catheter having at least one deflection wires includes a handle extending along an axis for being secured about a portion of the steerable catheter. The modular handle assembly includes at least one barrel rotatably connected to the handle for rotation about the axis, and at least one spindle disposed in and connected with said barrel for rotation about the axis with the barrel. At least one guide cable extends from an anchored end being anchored to the spindle to a distant end for connection with one of the deflection wires of the steerable catheter. The guide cable is wrapped about the spindle for axially moving the deflection wires in response to rotation of the first spindle about the axis by the barrel to curl the distal tip of the elongated body of the steerable catheter.

Abstract: A system and method for improved ultrasound strain imaging includes using data from a tracking system to enhance the quality of ultrasound strain image and to reduce the dependency of image quality of the user's expertise. The tracking information is synchronized with the RF frames and interpolated to find the transformation corresponding to each frame. The RF frames with their transformations are incorporated into calculation of ultrasound strain images. The tracking system may be an optical tracker, electromagnetic tracker, accelerometer, or a structured light system. The structured light system may also be used for probe calibration, by calibrating the surface of the probe pre-operatively. In addition, a relative Young's Modulus may be calculated using tracking information that is independent from the distribution of input force.

Abstract: The end-effector includes a sheath and a medical device or needle carrier that is disposed within the interior compartment of the sheath. An aperture is located in a portion of the sheath proximal a distal end of the sheath that is inserted into a natural or artificial cavity. This device is guided by a real-time imager.

Abstract: Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device includes three balloons that are each sized and shaped to fit within a concave portion of a valve cusp when inflated with a liquid and a shock wave source within each of the three balloons. Each balloon is separately and/or independently inflatable, and each shock wave source is separately and/or independently controllable. Methods of treating calcified heart valves using a shock wave device can include advancing a shock wave device having one or more balloons and a shock wave source in each of the balloons to contact a heart valve, inflating the one or more balloons with a liquid such that the balloon is seated within a concave portion of a valve cusp, and activating the shock wave source.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.