With Comparison Means (e.g., Ratio Of Or Comparison To A Standard) Patents (Class 600/475)
  • Patent number: 9915523
    Abstract: The invention relates to a system for monitoring a position of a distal end of a tube with respect to a blood vessel of a mammal. The system comprises a source for generating an outgoing beam of electromagnetic radiation having a predefined electromagnetic spectrum. The system furthermore comprises a guideway for guiding the outgoing beam to the distal end, and for guiding an incoming beam of electromagnetic radiation reflected by surroundings of the distal end in response to said outgoing beam to a measurement arrangement, which is arranged for measuring a parameter associated with an electromagnetic spectrum of the incoming beam. The system furthermore comprises a comparator arrangement for comparing said parameter with a reference parameter associated with a reference electromagnetic spectrum representing a predefined location of the distal end inside the mammal.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: March 13, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Judith Margreet Rensen, Wouter Harry Jacinth Rensen
  • Patent number: 9814417
    Abstract: Methods and apparatus are disclosed which facilitate the rapid, noninvasive and quantitative measurement of the concentration of flavonoid compounds, as well as their isomers and metabolites, in biological tissue such as human skin. Low-intensity, visible-light illumination of intact tissue provides for high spatial resolution, and allows for precise quantification of the flavonoid levels in the tissue. The preferred embodiments make use of a previously unknown, low-oscillator strength, optical absorption transition of flavonoids. This makes it possible to optically excite flavonoids in living human tissue outside the absorption range of other, potentially confounding skin chromophores.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: November 14, 2017
    Assignee: Longevity Link Corporation
    Inventors: Mohsen Sharifzadeh, Igor V. Ermakov, Werner Gellermann
  • Patent number: 9727962
    Abstract: The invention relates to a system for visualizing characteristic tissue with a colorant in a surgical region. The system contains a detection unit which detects light from at least one object point in the surgical region. The system has a computer unit which is connected to the detection unit and drives a visualization unit which displays an image of an area in the surgical region. The computer unit determines the color coordinate in a color space with respect to the light from a point from the object point in the surgical region. Depending on the position of the color coordinate determined with respect to the object point, the computer unit calculates a color coordinate information (“0”, “1”) for controlling the visualization unit by comparing information concerning the determined color coordinate of the object point with information concerning a characteristic reference color coordinate.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: August 8, 2017
    Assignee: Carl Zeiss Meditec AG
    Inventors: Christoph Hauger, Roland Guckler, Helge Jess, Joachim Steffen, Werner Nahm
  • Patent number: 9597482
    Abstract: A method and apparatus for inserting and monitoring the placement of a cannula tip within a peripheral vein of a human body where the cannula includes a sensor located at predetermined location and mounted on the cannula for sensing the biological material of the body to guide the insertion of the cannula tip into the vein and alerts to the withdrawal of the cannula tip from the vein in the body.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: March 21, 2017
    Assignee: Smart IV LLC
    Inventor: Lenn R. Hann
  • Patent number: 9599599
    Abstract: In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: March 21, 2017
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Stephen R. Ash, Thomas A. Sullivan, David Carr, Michael James Beiriger
  • Patent number: 9522033
    Abstract: A method of directing energy to tissue includes the initial step of positioning an energy applicator for delivery of energy to target tissue. The energy applicator is provided with a surface-contact detection device including one or more optical transmitters and one or more optical receivers. The energy applicator is operably associated with an electrosurgical power generating source. The method also includes the steps of determining whether a radiating portion of the energy applicator is disposed in contact with the target tissue based on a determination of whether optical signals generated by the one or more optical transmitters result in reflected optical signals received at the one or more optical receivers, and if it is determined that the radiating portion of the energy applicator is disposed in contact with tissue, transmitting energy from the electrosurgical power generating source through the radiating portion to the target tissue.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: December 20, 2016
    Assignee: COVIDIEN LP
    Inventor: Joseph D. Brannan
  • Patent number: 9365883
    Abstract: A spectroscopic method for spectroscopic detection and identification of bacteria in culture is disclosed. The method incorporates construction of at least one data set, which may be a spectrum, interference pattern, or scattering pattern, from a cultured sample suspected of containing said bacteria. The data set is corrected for the presence of water in the sample, spectral features are extracted using a principal components analysis, and the features are classified using a learning algorithm. In some embodiments of the invention, for example, to differentiate MRSA from MSSA, a multimodal analysis is performed in which identification of the bacteria is made based on a spectrum of the sample, an interference pattern used to determine cell wall thickness, and a scattering pattern used to determine cell wall roughness. An apparatus for performing the method is also disclosed, one embodiment of which incorporates a multiple sample analyzer.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: June 14, 2016
    Assignees: OPTICUL DIAGNOSTICS LTD., OPTICUL DIAGNOSTICS INC.
    Inventors: Gallya Gannot, Dror Lederman, Hassan Moinuddin, Israel Gannot
  • Patent number: 9320460
    Abstract: Apparatus, systems and methods employing contact lenses having one or more sensor that sense an analyte in tear fluid and one or more recesses that collect the tear fluid. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a recess formed within the substrate configured to collect tear fluid when the contact lens is worn. The contact lens further includes at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: April 26, 2016
    Assignee: Verily Life Sciences LLC
    Inventors: Zenghe Liu, James Etzkorn
  • Publication number: 20150148683
    Abstract: The invention relates to a method for determining the presence of a respiratory movement in a human or an animal. This method comprises the detection of a movement by a passive infrared detector and the analysis of signals transmitted by this detector. The invention also relates to an apparatus for executing a method of detecting a respiratory movement.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 28, 2015
    Inventor: Jean-Philippe Hermanne
  • Publication number: 20150126873
    Abstract: This invention is a wearable device to measure a person's consumption of selected types of food, ingredients, or nutrients comprising: a housing that is configured to be worn on the person's wrist, arm, hand, or finger; a spectroscopy sensor that collects data concerning light energy reflected from the person's body and/or absorbed by the person's body, wherein this data is used to measure the person's consumption of selected types of food, ingredients, or nutrients; a data processing unit; and a power source. The selected types of food, ingredients, or nutrients can be selected from the group consisting of: food that is high in simple carbohydrates; food that is high in simple sugars; food that is high in saturated or trans fat; fried food; food that is high in Low Density Lipoprotein (LDL); and food that is high in sodium.
    Type: Application
    Filed: November 4, 2013
    Publication date: May 7, 2015
    Inventor: Robert A. Connor
  • Patent number: 9026192
    Abstract: Devices and methods for optically scanning an in-vivo lumen, and for determining contact between an in-vivo device and an in-vivo lumen wall. The device may include an elongated housing having a cylindrical portion. At least one illuminating body may provide illumination at the circumference of the cylindrical portion, and at least one light sensor may sense light that penetrated and was scattered from the tissue of the in vivo lumen. The device may include a barrier for preventing direct illumination from the illuminating body from reaching the light sensor and for decreasing the amount of direct light reflection from the outer surface of the in vivo lumen onto the light sensor.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: May 5, 2015
    Assignee: Given Imaging Ltd
    Inventors: Shmuel Blit, Elisha Rabinovitz
  • Publication number: 20150099979
    Abstract: Various aspects of the instant disclosure are directed to imaging tissue. As may be implemented in accordance with one or more embodiments, aspects of the present disclosure are directed to apparatuses and methods involving the following. A light source includes an array of light emitters that illuminate a tissue region of a heart wall with light at different wavelength ranges. A light collector collects multispectral images including respective images collected at each of the different wavelength ranges at which the tissue region is illuminated. A catheter positions the light source and light collector proximate the tissue region of the heart wall for respectively illuminating the tissue region and collecting the multispectral images. A display circuit collects and displays one or more images depicting a condition of the health of heart wall tissue, based on the respective images collected at the different ones of the wavelength ranges.
    Type: Application
    Filed: October 8, 2014
    Publication date: April 9, 2015
    Inventors: Jeffrey Caves, Paul J. Wang, Joyce E. Farrell, Brian A. Wandell, Henryk Blasinski
  • Publication number: 20150099980
    Abstract: A device for detection of internal bleeding in a patient's body is provided. An optical interface for transmitting IR light through an area of a skin of a patient and to collect IR light from the area of the skin, is provided. In some embodiments the optical interface includes one or more delivery components and one or more collection components. The delivery component includes a plurality of first optical channels configured to transmit the IR light through a plurality of respective first sub-areas on the area of the skin, into an internal layer of the body. The collection component includes a plurality of second optical channels, configured to collect IR light from a plurality of respective second sub-areas on the area of the skin.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Dean Nahman, Yaron Ilan, Ilan Ben Oren, Yaron Bar-Ilan, Shmuel Chen
  • Publication number: 20150073271
    Abstract: Disclosed herein are systems and methods for revascularization assessment. The methods can in some cases include one or more of the steps of measuring blood perfusion as a function of time to obtain time series data, mathematically transforming the time series data into a power spectrum, calculating at least one parameter of the power spectrum within a specific frequency range, and using the at least one calculated parameter as a discriminator for the first population and the second population.
    Type: Application
    Filed: August 14, 2014
    Publication date: March 12, 2015
    Inventors: Kijoon Lee, Renzhe Bi, Jing Dong, Justin Dauwels
  • Publication number: 20150073282
    Abstract: The present invention provides a non-invasive device and method of detecting or evaluating brain damage in a living subject.
    Type: Application
    Filed: November 12, 2014
    Publication date: March 12, 2015
    Inventors: Eugene B. Hanlon, Frank A. Greco
  • Patent number: 8971997
    Abstract: An infrared fiber-optic device is able to monitor esophageal temperature during an ablation/cryoablation procedure over a volume of interest to sense whether the temperature is too high or too low. The device may include a plurality of optical fibers each with a wide angle lens collectively disposed circumferentially and longitudinally to cover the volume of interest, as the particular region over which undesirable temperature may not be known beforehand. In other examples, the device may include an embedded array of infrared sensors extending sufficiently to encompass a volume of interest. The device may be used as part of a feedback control to regulate and stop operation of the ablation/cryoablation procedure to prevent vessel damage.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: March 3, 2015
    Assignee: The Regents of the University of Michigan
    Inventors: Hakan Oral, Fred Morady
  • Patent number: 8971998
    Abstract: The present invention relates to systems and methods for detecting biomaterial anomalies in a test subject for diagnosing existing and potential medical conditions. The general technique utilized is to expose a portion of the test subject to low doses of RF electromagnetic energy. Different biomaterials in a test subject may be differentiated and identified by characterizing their electromagnetic properties based on observed parameters, e.g., electromagnetic energy absorbed, thermal energy created, and electromagnetic energy emitted, during irradiation of the test subject. This invention allows for the efficient utilization of multiple frequency bands allowed by the FCC, as well as a more precise distribution of electromagnetic energy to the test subject.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 3, 2015
    Assignee: Integral ElectroMagnetronic Technologies LLC
    Inventors: Albert Francis Messano, Jr., Mandeep Singh
  • Patent number: 8971984
    Abstract: This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: March 3, 2015
    Assignee: Hypermed Imaging, Inc.
    Inventors: Jenny E. Freeman, Svetlana V. Panasyuk, Michael J. Hopmeier, Derek Brand, Kevin Schomacker
  • Publication number: 20150057511
    Abstract: An optical proximity sensor assembly includes an optical proximity sensor with an IR LED emitting light having an infrared wavelength, an IR photo detector sensitive to the infrared wavelength, an optical barrier blocking direct light rays from the LED to the IR photo detector and permitting reflected light rays to reach the at least one photo detector; and an electronic integrated circuit with an amplifier for amplifying a signal detected by the photo detector, an analog to digital converter, LED drivers, noise reduction and ambient light cancellation circuitry, and a digital interface for communication with a microcontroller. The optical proximity sensor is accommodated on a wearable carrier. A single sensor may include a plurality of identical or different LEDs, a plurality of photodiodes, or both. Also, several sensors may be placed on a person's skin along a vascular path to obtain data relating to blood flow and artery stiffness.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 26, 2015
    Inventor: Amar Sarbbasesh Basu
  • Patent number: 8954133
    Abstract: The present invention provides a non-invasive device and method of detecting or evaluating brain damage in a living subject.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: February 10, 2015
    Assignee: The United States of America as represented by the Department of Veterans Affairs
    Inventors: Eugene B. Hanlon, Frank A. Greco
  • Patent number: 8948850
    Abstract: Methods and apparatus are provided which in some implementations a non-contact thermometer determines a temperature of a subject from a carotid source point of the subject.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: February 3, 2015
    Assignee: Arc Devices Limited
    Inventor: Jason Roth
  • Patent number: 8932223
    Abstract: A design and a fabrication method for an intravascular imaging and therapeutic catheters for combined ultrasound, photoacoustic, and elasticity imaging and for optical and/or acoustic therapy of hollow organs and diseased blood vessels and tissues are disclosed in the present invention. The invention comprises both a device—optical fiber-based intravascular catheter designs for combined IVUS/IVPA, and elasticity imaging and for acoustic and/or optical therapy—and a method of combined ultrasound, photoacoustic, and elasticity imaging and optical and/or acoustic therapy. The designs of the catheters are based on single-element catheter-based ultrasound transducers or on ultrasound array-based units coupled with optical fiber, fiber bundles or a combination thereof with specially designed light delivery systems. One approach uses the side fire fiber, similar to the one utilized for biomedical optical spectroscopy.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: January 13, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Stanislav Emelianov, Andrei Karpiouk, Bo Wang
  • Patent number: 8918162
    Abstract: A sequence of three-dimensional thermal infrared images of the face or other area of the body is analyzed to extract time-varying maps which link skin surface temperature details to the locations of anatomical structures. Frame-to-frame quantitative variations in temperature and position of anatomical nodes of the body maps are determined for the sequence and compared to reference profiles to produce estimates of physiological condition and psychological state. The magnitude, latency, and duration of such variations at particular anatomical locations resulting from selected controlled stimuli have been determined to be strongly correlated with particular psychological states.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: December 23, 2014
    Inventor: Francine J. Prokoski
  • Patent number: 8903474
    Abstract: Systems and techniques for the analysis of gases for medical purposes are described. In one aspect, a system includes a sample collector to collect a physical sample associated with an individual and present a gas sample for analysis, a gas analysis device to analyze the gas sample presented by the sample collector to determine a concentration of one or more non-aqueous gases in the gas sample, a data storage device that includes information reflecting a correlation between concentration of the one or more non-aqueous gases in the gas sample and a disease state, and a data analysis device to determine a medical condition of the individual based on the concentration of one or more non-aqueous gases in the gas sample and the information.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: December 2, 2014
    Assignee: PEN Inc.
    Inventors: Zvi Yaniv, Prabhu Soundarrajan
  • Patent number: 8879812
    Abstract: The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: November 4, 2014
    Assignee: Cambridge Research & Instrumentation, Inc.
    Inventors: Richard Levenson, Paul J. Cronin, Kirk William Gossage, Clifford C. Hoyt
  • Publication number: 20140323875
    Abstract: According to one embodiment, an apparatus for detecting obstructions in biological vessels includes a cylindrical hollow stent with an expandable body portion having an outer surface configured to engage the inner surface of the lumen of the vessel to urge the vessel against collapse, and an imaging system operatively coupled with stent. The imaging system includes a first power source, a light generating element, a light sensor generating a first signal representative of light received by the sensor element from the light generating elements, and a processor unit receiving the first signal and processing the first signal in accordance with image processing logic stored in a memory of the processor unit to generate an image signal representative of as image of associated target material such as plaque obstructing the flow. The imaging system and stent may be formed on opposite sides of a flexible organic substrate.
    Type: Application
    Filed: April 25, 2013
    Publication date: October 30, 2014
    Applicant: Toshiba America Electronic Components, Inc.
    Inventor: Rakesh SETHI
  • Patent number: 8874194
    Abstract: An apparatus which can detect leak of a liquid injected through an injection needle into a blood vessel of a human body near its surface with high accuracy. The apparatus emits a light ray in a predetermined wavelength band containing a particular wavelength at which the reflectivity for the liquid is lower than the reflectivity for internal tissues of the human body, and detects the light ray in the wavelength band reflected inside the human body. The leak of the liquid can be detected without being affected by variations in the human body or physical condition.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: October 28, 2014
    Assignee: Nemoto Kyorindo Co., Ltd.
    Inventors: Seiichi Ono, Masahiro Sakakibara
  • Patent number: 8868157
    Abstract: A system and method for assessing a peripheral neuropathy risk wherein the system and method according to one embodiment of the present invention detects abnormality which may be directed to a probability, a stage, a category, or other indicator as to the degree of progression of the disease.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: October 21, 2014
    Assignee: VisionQuest Biomedical LLC
    Inventor: Peter Soliz
  • Patent number: 8868158
    Abstract: An optical analyzer performing analysis excellent in spatial resolution and in invasion depth is provided.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: October 21, 2014
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventor: Takemi Hasegawa
  • Patent number: 8855749
    Abstract: Methods and systems are provided for analyzing a physiological signal by applying a continuous wavelet transform on the signal and comparing the wavelet transformation to a library of wavelet signatures corresponding to one or more physiological conditions and/or patient conditions. A pulse oximeter system may relate the wavelet transformation with one or more of the wavelet signatures based on filters and/or thresholds, and may determine that the wavelet transformation indicates that the patient of the physiological signal has a physiological condition indicated by the related wavelet signature. In some embodiments, the pulse oximeter system may use previous analyses in a neural network to update the library. Further, non-physiological components of the wavelet transformation may also be identified and removed.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: October 7, 2014
    Assignee: Covidien LP
    Inventor: Edward M. McKenna
  • Patent number: 8831710
    Abstract: A medical observation system, which includes a medical probe that observes a subject by scanning on the subject with laser light; a laser source that supplies the laser light to the medical probe; a judgment unit that judges whether the medical probe is in a predetermined state; and a control unit that controls an amount of laser light emitted from the laser source based on a judgment result by the judgment unit.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: September 9, 2014
    Assignee: Hoya Corporation
    Inventor: Shotaro Kobayashi
  • Patent number: 8818493
    Abstract: An apparatus and method for creating a three dimensional imaging system is disclosed. There is a first source of laser light and a second source of laser light having a wavelength different from the wavelength of the laser light of the first source. The laser light from the first and second sources are combined, and the combined laser light is transmitted to a scanner. The scanner further transmits the combined light to a surface to be imaged.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: August 26, 2014
    Assignee: AccuVein, Inc.
    Inventors: Ron Goldman, Fred Wood, Vincent Luciano, Stephen Conlon
  • Publication number: 20140236021
    Abstract: A system and method for using near-infrared or short-wave infrared (SWIR) light sources for early detection and monitoring of breast cancer, as well as other kinds of cancers may detect decreases in lipid content and increases in collagen content, possibly with a shift in the collagen peak wavelengths and changes in spectral features associated with hemoglobin and water content as well. Wavelength ranges between 1000-1400 nm and 1600-1800 nm may permit relatively high penetration depths because they fall within local minima of water absorption, scattering loss decreases with increasing wavelength, and they have characteristic signatures corresponding to overtone and combination bands from chemical bonds of interest, such as hydrocarbons. Broadband light sources and detectors permit spectroscopy in transmission, reflection, and/or diffuse optical tomography. High signal-to-noise ratio may be achieved using a fiber-based super-continuum light source.
    Type: Application
    Filed: December 17, 2013
    Publication date: August 21, 2014
    Applicant: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 8812083
    Abstract: Optical changes of tissue during wound healing measured by Near Infrared and Diffuse Reflectance Spectroscopy are shown to correlate with histologic changes. Near Infrared absorption coefficient correlated with blood vessel in-growth over time, while Diffuse Reflectance Spectroscopy (DRS) data correlated with collagen concentration. Changes of optical properties of wound tissue at greater depths are also quantified by Diffuse Photon Density Wave (DPDW) methodology at near infrared wavelengths. The diffusion equation for semi-infinite media is used to calculate the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain or time domain device. An increase in the absorption and scattering coefficients and a decrease in blood saturation of the wounds compared to the non wounded sites was observed. The changes correlated with the healing stage of the wound.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: August 19, 2014
    Assignees: Philadelphia Health & Education Corporation, Drexel University
    Inventors: Elisabeth S. Papazoglou, Leonid Zubkov, Michael T. Neidrauer, Linda Zhu, Kambiz Pourrezaei, Michael S. Weingarten
  • Patent number: 8810658
    Abstract: What is disclosed is a system and method for estimating color for pixels in an infrared image. In one embodiment, an infrared image is received which has been captured using a N-band infrared imaging system comprising a multi-spectral camera or a hyperspectral camera. The IR image is composed of an array of pixels with N intensity values having been collected for each pixel in the image. Then, for each pixel of interest, a search metric is used to search a database of vector samples to identify a visible-IR set which is closest to the intensity values of the IR band vector collected for the pixel. A visible vector representation is then estimated for the pixel based upon the visible portion corresponding to the closest visible-IR set. Thereafter, color coordinates for this pixel are computed from the visible vector. The method repeats for all pixels of interest in the IR image.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: August 19, 2014
    Assignee: Xerox Corporation
    Inventors: Sandra Skaff, Raja Bala, Lalit Keshav Mestha, Beilei Xu
  • Patent number: 8812084
    Abstract: The present invention relates to systems and methods for detecting biomaterial anomalies in a test subject for diagnosing existing and potential medical conditions. The general technique utilized is to expose a portion of the test subject to low doses of RF electromagnetic energy. Different biomaterials in a test subject may be differentiated and identified by characterizing their electromagnetic properties based on observed parameters, e.g., electromagnetic energy absorbed, thermal energy created, and electromagnetic energy emitted, during irradiation of the test subject.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: August 19, 2014
    Inventors: Albert Francis Messano, Jr., Mandeep Singh
  • Publication number: 20140213908
    Abstract: A portable electronic device includes an infrared touch screen and a processor. The infrared touch screen includes a detection unit, a filter unit, and a signal conversion unit. The detection unit detects the intensity of the infrared beams reflected by a user's body part placed on the infrared touch screen, and converts the detected intensity of the infrared beam to electrical signals. The filter unit filters the electrical signals and amplifies the filtered electrical signals. The signal conversion unit converts the electrical signals to digital signals. The processor includes an information processing module and a display control module. The information processing module processes the digital signals to obtain the heart rate information of the user, and creates a heart rate monitoring result according to the heart rate information of the user. The display control module controls the infrared touch screen to display the heart rate monitoring result.
    Type: Application
    Filed: April 12, 2013
    Publication date: July 31, 2014
    Applicant: HON HAI PRECISION INDUSTRY CO., LTD.
    Inventor: CHIH-CHUNG WENG
  • Patent number: 8774905
    Abstract: Methods are provided for detecting lipid cores underneath thin fibrous caps (LCTC) and thin-cap fibroatheromas (TCFA) in a subject in need of diagnosis for having a vulnerable plaque, a plaque at risk of disruption or thrombosis, or risk of an acute coronary syndrome, and for screening compounds for modulators of this process.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: July 8, 2014
    Assignee: Lahey Clinic Foundation, Inc.
    Inventors: Sergio Waxman, Fumiyuki Ishibashi
  • Patent number: 8774902
    Abstract: A device and method to diagnose an internal abnormality in a living subject by sensing a passively occurring electromagnetic radiation signal associated with the abnormality and inside an orifice of the subject. Diagnosis includes detection, imaging or identification of the abnormality. An instrument is used either to bring a sensor into the orifice or to transmit the signal to a sensor located outside of the orifice. An example of the instrument includes a prior art endoscope.
    Type: Grant
    Filed: April 1, 2007
    Date of Patent: July 8, 2014
    Assignee: Passive Imaging Medical Systems Engineering Ltd. (PIMS)
    Inventors: Ben Zion Dekel, Nathan Blaunshtein, Arkadii Zilberman
  • Patent number: 8750970
    Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: June 10, 2014
    Inventors: Ron Goldman, David Hunt, Mark Mock, Graham Marshall, Stephen P. Conlon, Bob Roth
  • Patent number: 8750968
    Abstract: A first aspect of the invention relates to a device for a diagnosis and/or therapy monitoring of inflammatory diseases, such as rheumatoid arthritis. It comprises at least a rest or support device (1) for holding at least one extremity (11) of a person. Thereby, the support device has the task of facilitating the at least one extremity, preferably two extremities, for instance the two hands to be comfortably and immovably placed as long as possible. This support device can be provided with a rest with several accessories, such as indentations, bowl-like recesses, ridges, elastic or non-elastic straps and/or loops, etc. Furthermore, at least an excitation source (2) for at least partially illuminating one extremity at least with a radiation of defined excitation wavelength. Furthermore, at least an image sensor (3) is incorporated for capturing at least a reference signal from the extremity as well as several signals from the regions of medical interest (ROI) of the extremity (11).
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: June 10, 2014
    Assignee: MIVENION GmbH
    Inventor: Malte Bahner
  • Patent number: 8738116
    Abstract: A technique for obtaining information regarding a state of periodontal tissue involves deriving a substantially whole curve measure of similarity of an observed bandshape of an isolated spectral component attributed to water within the infrared region. Subtle variations in the bandshape of the water bands have been found to correlate with inflammatory periodontal diseases and using whole curve measures such as weighted integrals or measure of fit parameters these variations can be detected and used to classify periodontal tissues.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: May 27, 2014
    Assignee: National Research Council of Canada
    Inventors: Kan-Zhi Liu, Mike G. Sowa
  • Publication number: 20140135597
    Abstract: A system for measuring and converting to an observer intelligible form an internal physiological parameter of a patient. The invention allows transcutaneous telemetry of intracranial pressure via a system which includes a patient implanted sensor module and an external processing module, optically coupled to the sensor module via an external coupling module. A sensor within the sensor module transduces the measured pressure and a near infrared emitter transmits the telemetry when interrogated by the external coupling module. A set of tuned inductor-crystal circuits comprised in part of a cylindrical crystal oscillator whose resonant frequency is sensed by a dipper circuit arrangement is provided. Power for the sensor module is derived inductively through rectification of a transcutaneously-applied high-frequency alternating electromagnetic field generated within the external coupling module.
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Inventor: Erich W. Wolf, II
  • Patent number: 8725236
    Abstract: A method for demonstrating pre-emergent pimples is disclosed. The method includes providing a camera having a 25 mm macro lens and a linear polarizing filter including from 10 to 50 narrow band filters in the spectral range of 400-970 nm, and a light source having a linear polarizer oriented vertical to a polarization plane of the camera polarizer; taking a sequence of images of the face of a subject with the camera; creating an erythema map of the imaged area using oxy-hemoglobin values at each corresponding pixel; taking a visible-light image of the face of the subject; and comparing the images to see pre-emergent pimples. The method enables consumers to see pre-emergent pimples and treat them, which results in preventing the pimples from emerging or reducing the emergence of the pimples.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: May 13, 2014
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Nikiforos Kollias, Georgios N. Stamatas
  • Patent number: 8718749
    Abstract: A vessel pulse wave measurement system performs vessel pulse wave measurement using an optical probe circuit provided with an optical probe including a light emitting element and a light receiving element, a drive circuit, and a detection circuit. A measurement device directly and synchronously feeds back an electrical signal from the optical probe to the drive circuit as a drive signal to generate a self-oscillation signal from the detection circuit, and measures the self-oscillation signal as a vessel pulse wave signal. A controller controls an operating point of at least one of the detection circuit and the drive circuit such that the self-oscillation signal substantially reaches a maximum level thereof.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: May 6, 2014
    Assignee: Act Medical Service Co., Ltd.
    Inventors: Seiichi Takenoshita, Shintaro Chiba, Yutaka Hata, Tokuko Saito Wiedemann, Hiromichi Annoh, Asako Yagi, Shinichi Takahashi, Fukuto Handa, Toshikuni Yajima
  • Patent number: 8688199
    Abstract: A method of aiding in the diagnosis or prediction of degenerative joint disease in a joint of a patient. The method comprises obtaining a test spectrum of Raman scattered radiation from cartilage tissue in the joint, and analyzing the test spectrum, or one or more regions thereof, to assess whether the test spectrum is consistent with the patient having, or subsequently developing, degenerative joint disease in the joint.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: April 1, 2014
    Assignee: UCL Business PLC
    Inventors: Jayesh Dudhia, Paul Francis McMillan, Edward Richard Cornell Draper, Steven Firth
  • Patent number: 8682417
    Abstract: Methods for detection of heat-related symptoms can include use of a thermal sensor to obtain thermal data. Subsets of the thermal data can correspond with multiple subjects. The subsets can be compared to determine whether any of the subjects is a thermal outlier relative to the remaining subjects.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: March 25, 2014
    Assignee: Intermountain Invention Management, LLC
    Inventor: Glen Forrest Huff
  • Publication number: 20140066781
    Abstract: A medical diagnosis device and a method for controlling the device that detect an abnormal portion of a diagnosis target early and accurately are provided. A medical diagnosis device according to an embodiment of the present invention includes: a light source configured to irradiate light onto a diagnosis target; an optical filter configured to filter out visible light and infrared light from light reflected from the diagnosis target and convert an optical path of the filtered visible or infrared light; a polarization beam splitter configured to polarize the infrared light filtered by the optical filter; a first image acquisition unit configured to acquire a first image from the visible light filtered by the optical fiber; and a second image acquisition unit configured to acquire a second image from the infrared light polarized by the polarization beam splitter.
    Type: Application
    Filed: April 25, 2013
    Publication date: March 6, 2014
    Applicant: Electronics and Telecommunications Research Institute
    Inventor: Electronics and Telecommunications Research Institute
  • Publication number: 20140052003
    Abstract: An infrared detector includes a radiation source configured to emit electromagnetic radiation. The detector includes a source monitoring apparatus configured to generate output signals (62) related to electrical resistance through the radiation source. The output signals are used to account for radiation source temperature in measurements by the detector. The output signals may be used (72) in the provision of power to the radiation source to maintain the temperature of the detector at a beneficial level. The detector is configured to monitor a level of a gaseous molecular species within a flow of breathable gas.
    Type: Application
    Filed: April 4, 2012
    Publication date: February 20, 2014
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: Zhi-Xing Jiang, Anthony Pierry
  • Patent number: 8634607
    Abstract: The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: January 21, 2014
    Assignee: Cambridge Research & Instrumentation, Inc.
    Inventors: Richard Levenson, Paul J. Cronin, Kirk William Gossage, Clifford C. Hoyt