Infrared Radiation Patents (Class 600/473)
  • Patent number: 10776915
    Abstract: A medical image processing apparatus includes: a medical image acquisition unit that acquires a medical image; a medical image analysis result acquisition unit that acquires an analysis result of the medical image; a display unit that displays the medical image and the analysis result; a correspondence relationship setting unit that sets a correspondence relationship between a first analysis result of a first medical image and a second analysis result of a second medical image having different imaging conditions from the first medical image; and a display control unit that sets a display form in case of displaying the second analysis result on the first medical image using the set correspondence relationship or sets a display form in case of displaying the first analysis result on the second medical image using the set correspondence relationship.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: September 15, 2020
    Assignee: FUJIFILM Corporation
    Inventor: Norimasa Shigeta
  • Patent number: 10758142
    Abstract: A device and method is described for electronic human prosthetics, and specifically a body-machine interface (BMI) device where the input, output and on-board computing are combined into a single unit to form a compact ECG, respiratory sensing, temperature-sensing-prosthetics device. The devices (BMIs) can also communicate with other body-machine interface devices (BMI) and/or with external controllers wirelessly. The compact device has ultrasonic battery charging system. One or more BMI can be wirelessly connected so that a closed loop of BMIs, or a BMI and an external controller, can wirelessly send trigger pulses to the stimulator over the heart, glossopharyngeal nerve(s) or diaphragm.
    Type: Grant
    Filed: July 14, 2018
    Date of Patent: September 1, 2020
    Assignees: San Diego State University Research Foundation, Electronic and Telecommunication Research Institute
    Inventors: Kee S. Moon, Sung Q. Lee, Woosub Youm
  • Patent number: 10750873
    Abstract: A furniture system includes an office productivity structure (OPS). The furniture system also includes a sensor coupled to the OPS, the sensor operable to detect a parameter of the OPS and generate an output signal indicative of the parameter; and a processor coupled to the sensor. The processor is operable to receive the output signal generated by the sensor, determine, based on the output signal, an operation condition of the OPS, when the operation condition is determined to be within a satisfactory range, determine an estimated time before servicing is needed, and when the operation condition is determined to be outside a satisfactory range, send a service alert.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: August 25, 2020
    Assignee: HERMAN MILLER, INC.
    Inventors: Christopher Hoyt, Daniel Rucker, Joseph Doran, Brian Alexander, Adam Daley-Fell
  • Patent number: 10750984
    Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: August 25, 2020
    Assignee: Cercacor Laboratories, Inc.
    Inventors: Kevin Pauley, Cristiano Dalvi, Hung Vo, Jesse Chen, Ferdyan Lesmana, Jeroen Poeze, Sean Merritt
  • Patent number: 10722105
    Abstract: A medical imaging device includes: a spectroscopic unit that separates light into a first light component of a wavelength band and a second light component; a first imaging element that includes a plurality of first pixels configured to receive the first light component and convert the first light component into electric signals; and a second imaging element that includes a plurality of second pixels and includes a first color filter on which first filters configured to transmit the light component of the wavelength band of one color in the light components of the wavelength bands of two colors that are contained in the second light component and second filters configured to transmit light components of a plurality of wavelength bands including at least the wavelength band of another color in the light components of the wavelength bands of the two colors are arranged.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: July 28, 2020
    Inventors: Motoaki Kobayashi, Yuichi Yamada
  • Patent number: 10723226
    Abstract: A pattern recognition system receives an image captured by an image capture device, of an operator and the operator is identified. Operator information is accessed, based upon the identified operator, and a control signal is generated to control a mobile machine, based upon the operator information.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: July 28, 2020
    Assignee: Deere & Company
    Inventors: Joshua C. Heitsman, Reginald M. Bindl, Keith N. Chaston, Michael G. Kean, John M. Hageman, Mark J. Cherney, Sean P. West
  • Patent number: 10687697
    Abstract: An endoscopic system having a light source that can operate in two modes is provided. The first mode provides a white light to an endoscope to transmit the light to a surgical site or other object, the reflection of which can be received by the endoscope and for the process. The second mode of the light source provides infrared excitation light and light in the blue and green wavelength spectra to an endoscope to transmit the light to an object such as a surgical site. The blue and green reflected light, as well as light from excitation markers, which is an infrared light at a different wavelength than the excitation infrared light, is received by the endoscope and further processed.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 23, 2020
    Assignee: Stryker Corporation
    Inventors: Ajay Ramesh, Perry Hu, Harman Singh, Chien Mien Pang, Vasudev Nambakam
  • Patent number: 10682112
    Abstract: A medical image viewing device for navigation in X-ray imaging includes a processor. The processor is configured to perform a 3D-2D registration of a preoperative three-dimensional volume based on geometry parameters of an image data provider, which provides fluoroscopy images of an object of interest and a plurality of structures with interfering motions to be removed, for creating digitally reconstructed radiograph images of these structures for each fluoroscopy image. These are subtracted from the respective fluoroscopy images to generate structure-suppressed fluoroscopy images free from interfering motions. Based on these structure-suppressed fluoroscopy images, an angiographic image sequence is generated performing a motion estimation of the structures.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: June 16, 2020
    Inventors: Guilaume Julien Joseph Pizaine, Pascal Yves Francois Cathier, Olivier Pierre Nempont, Raoul Florent
  • Patent number: 10663596
    Abstract: Disclosed herein is a ladar system that includes a ladar transmitter, ladar receiver, and camera, where the camera that is co-bore sited with the ladar receiver, the camera configured to generate image data corresponding to a field of view for the ladar receiver. In an example embodiment, a mirror can be included in the optical path between a lens and photodetector in the ladar receiver, where the mirror (1) directs light within the light from the lens that corresponds to a first light spectrum in a first direction for reception by the camera and (2) directs light within the light from the lens that corresponds to a second light spectrum in a second direction for reception by the photodetector, wherein the second light spectrum includes ladar pulse reflections for processing by the ladar system.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: May 26, 2020
    Assignee: AEYE, INC.
    Inventors: Luis Carlos Dussan, Allan Steinhardt, Joel David Benscoter, Jordan Spencer Greene
  • Patent number: 10660533
    Abstract: Systems and methods are disclosed to measure a PPG signal. In some embodiments, a method may include capturing a plurality of frames of a subject; tracking the position of a region of interest of the subject in each of the plurality of frames; creating a first time series signal, a second time series signal, and third time series signal corresponding with respective color channels of the plurality of frames; normalizing the first, second, and third time series signals, combining the normalized first time series signal, the normalized first time series signal, and the normalized first time series signal into a combined signal; creating a spectral signal from the combined signal; and extracting the PPG signal from the spectral signal.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: May 26, 2020
    Assignee: RAPSODO PTE. LTD.
    Inventors: Kelvin Yeo Soon Keat, Batuhan Okur
  • Patent number: 10649198
    Abstract: Sample handling, processing and analysis methods and apparatus are described. According to one aspect, a sample processing method includes providing a sample, providing a reference frame which comprises a plurality of markers arranged in a predefined pattern, wherein individual ones of the markers are uniquely identifiable from others of the markers, and associating the reference frame comprising the markers with the sample. The markers are amenable to human or machine reading and for computational manipulation in some examples.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: May 12, 2020
    Assignee: Battelle Memorial Institute
    Inventors: Micah D. Miller, James Preston McKinley
  • Patent number: 10649206
    Abstract: A light sensing method applied to a light sensing system comprising a first light sensor and at least one light source. The first light sensor comprises a plurality of light sensing units. The light sensing method comprises: (a) respectively controlling an exposure condition for each of the light sensing units according distances between each one of the light sensing units and the light source; and (b) controlling the light sensing units to sense the light from the light source according to the exposure condition. The light sensing system can have a better SNR via adjusting the exposure condition for each one of the light sensing units. Such light sensing method can be applied to compute physiological parameters.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: May 12, 2020
    Assignee: PixArt Imaging Inc.
    Inventors: Ren-Hau Gu, Chih-Hsin Lin
  • Patent number: 10646178
    Abstract: The present disclosure relates to a cabinet x-ray and ultrasound system and method for obtaining x-ray images and ultrasound images of a specimen and more specifically, a system and method including a cabinet defining an interior chamber, a display, an x-ray system and an ultrasound system.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: May 12, 2020
    Inventors: Vikram Butani, Chester Lowe, Yan Chen, Roberto Velasco, Edwin Divakaran Maria-Selvaraj, Vignesh Mandalapa-Bhoopathy, Timothy Ely
  • Patent number: 10624587
    Abstract: An example method for estimating a disease state for a patient can include: capturing physiological data including images from the patient over time; processing the physiological data to detect a variability; comparing the variability to a baseline or a range; and estimating the disease state for the patient based upon the comparing of the variability to the baseline or the limit.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: April 21, 2020
    Assignee: WELCH ALLYN, INC.
    Inventors: Steven D. Baker, Chau Chong Ye, Yue Wang, Aye Aung
  • Patent number: 10596392
    Abstract: A radiotherapy system including a radiotherapy component, a structural imaging component, a functional imaging component, and a workstation coupled to the radiotherapy component, the structural imaging component, and the functional imaging component. The workstation includes a processor which combines the structural imaging data and the functional imaging data to produce a fused model for a least a portion of the region of interest, to generate a plan for radiotherapy treatment of the region of interest based on the fused model, and apply, via the radiotherapy component, the radiotherapy treatment.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: March 24, 2020
    Inventor: Kalman Fishman
  • Patent number: 10569100
    Abstract: Disclosed herein is a method for regenerating retinal tissue which includes preparing a luminescent scaffold, implanting the luminescent scaffold in a portion of retina, for example subretinal area, emitting a green light from the luminescent nanoparticles in a luminescence phenomenon, and absorbing the emitted light by retinal cells for regenerating retinal tissue by stimulating the retinal cells. Moreover, preparing a luminescent scaffold may comprise synthesizing a plurality of luminescent particles, dispersing the luminescent particles in a polymeric matrix to form a luminescent composite, and electrospinning the luminescent composite to form the luminescent scaffold.
    Type: Grant
    Filed: September 17, 2017
    Date of Patent: February 25, 2020
    Inventor: Azadeh Sepahvandi
  • Patent number: 10564103
    Abstract: A dual-mode optical molecular imaging navigation apparatus with a switchable field of view, and an imaging method thereof, are provided in the embodiments of the disclosure, the apparatus including: a camera module configured to perform a color imaging and a fluorescence imaging; a switching module configured to switch between an open imaging mode and an endoscopic imaging mode as per imaging requirements; an open imaging module configured to perform observation and imaging with a large field of view; an endoscopic imaging module configured to perform observation and imaging with a deep field of view; a data processing module configured to provide a camera control software and image capturing, processing and display method; and a support module configured to support and connect the navigation apparatus.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: February 18, 2020
    Inventors: Jie Tian, Yamin Mao, Chongwei Chi, Xin Yang
  • Patent number: 10555673
    Abstract: A probe (1) is used in an optical coherence tomography device which irradiates measurement light to a subject and collects scattered light that has returned from the subject after being reflected. The probe (1) is provided with a scanning means (70) composed of galvanometer mirrors (72, 73) that change an irradiation direction of the measurement light. The scanning means (70) is provided with actuators (72b, 73b) which switch reflecting mirrors (72a, 73a) that reflect the measurement light between a state where the measurement light is reflected by the subject and returns as the scattered light, and a state where the measurement light is diffusely reflected within the probe (1).
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: February 11, 2020
    Inventor: Hideo Kakuma
  • Patent number: 10548513
    Abstract: A variety of techniques are used automate the collection and classification of workout data gathered by a wearable physiological monitor. The classification process is staged in order to correctly and efficiently characterize a workout type. Initially, a generalized workout event is detected using motion and heart rate data. Then a location of the monitor on a user is determined. An artificial intelligence engine can then be conditionally applied (if a workout is occurring and a suitable device location is detected) to identify the type of workout. In addition to improved speed and accuracy, a workout detection process implemented in this manner can be realized with a sufficiently small computational footprint for deployment on a wearable physiological monitor.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: February 4, 2020
    Assignee: Whoop, Inc.
    Inventors: Brian Anthony Todd, John Vincenzo Capodilupo, Emily Rachel Capodilupo, William Ahmed
  • Patent number: 10551357
    Abstract: A method for high resolution photoacoustic imaging in scattering media using structured illumination may include illuminating a sample of an absorption object with structured illumination, including illuminating the sample with multiple different speckle patterns at different times. The method may also include detecting multiple photoacoustic signals generated by the absorption object in response to illumination with the different speckle patterns to generate multiple photoacoustic responses. The method may also include reconstructing an absorber distribution of the absorption object by exploiting joint sparsity of sound sources in the plurality of photoacoustic responses.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: February 4, 2020
    Assignees: The Regents of the University of Colorado, a body corporate, Research Center for Non Destructive Testing GmbH, University of Innsbruck
    Inventors: Todd W. Murray, Peter Burgholzer, Markus Haltmeier
  • Patent number: 10531921
    Abstract: The present invention relates to a method for determining a state of tissue sealing during a tissue sealing process. According to the disclosed method, an optical probe beam is used to irradiate a tissue region. A signal indicative of optical scattering in the tissue region is generated from a portion of the optical probe beam that has passed through or been returned by the tissue region. The onset of tissue sealing is indicated by the successive occurrence in time of a turning point and a point of inflection in the optical scattering signal. An energy-based tissue sealing or tissue-cutting device for use in accordance with the method is also disclosed.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: January 14, 2020
    Inventors: Bernardus Hendrikus Wilhelmus Hendriks, Torre Michelle Bydlon, Vishnu Vardhan Pully, Charles Frederik Sio, Sandra Martina Van Den Bosch, Gerhardus Wilhelmus Lucassen
  • Patent number: 10521893
    Abstract: An image processing apparatus includes: an acquisition unit configured to acquire band images of an object, using filters of which transmission center wavelengths are different from each another; a detection unit configured to select a first band image from the band images, and detect a target region that is to be improved with respect to visibility; a selection unit configured to select a second band image, which includes information, originated from a structure of the object, within the target region, from among the band images other than the first band image; and a generation unit configured to generate a spectral image from a band image. The generation unit uses at least a band image that has been captured using a same filter as the second band image, upon generating a spectral image of the object.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: December 31, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventors: Toshiki Shiga, Toru Sasaki
  • Patent number: 10492678
    Abstract: An image processing apparatus includes an image input that receives input of image data of a captured human being, a region detector that detects a specific color region of the image data, a filter that smooths a pixel value in the specific color region detected by the region detector by using a frame of the image data input into the image input and each of previous and subsequent frames of the image data of the inputting into the image input, a coder that codes an output image of the filter, and an output that outputs the output image of the filter coded by the coder.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: December 3, 2019
    Inventors: Ryoji Ogino, Tsuyoshi Nakamura, Junya Kuwada
  • Patent number: 10483006
    Abstract: A computer-implemented method for providing a personalized evaluation of assessment of atherosclerotic plaques for a patient acquiring patient data comprising non-invasive patient data, medical images of the patient, and blood biomarkers. Features of interest are extracted from the patient data and one or more machine learning models are applied to the features of interest to predict one or more measures of interest related to atherosclerotic plaque.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: November 19, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Lucian Mihai Itu, Tiziano Passerini, Saikiran Rapaka, Puneet Sharma, Dorin Comaniciu
  • Patent number: 10469723
    Abstract: In implementations of photography lighting control, a camera device includes a camera to capture an image of a subject in an environment. The camera device implements an image exposure module that can determine ambient lighting conditions of the environment, and discover fixed light sources that are usable to illuminate the subject for image capture in the environment. The image exposure module can determine optimal lighting for the image capture of the subject in the environment, as well as control one or more of the fixed light sources used to adjust the ambient lighting conditions of the environment for the optimal lighting and the image capture of the subject. The image exposure module can then initiate use of the controlled fixed light sources to capture the image of the subject.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: November 5, 2019
    Assignee: Motorola Mobility LLC
    Inventors: John Christopher Pincenti, Alberto R. Cavallaro, Robert S. Witte
  • Patent number: 10460833
    Abstract: A method for storing data of photoelectrically synchronous brain activity recording, said method comprising: generating data when a photoelectrically synchronous brain activity detection system is operating; generating from said data a data storage file comprising a basic information data segment, a near-infrared spectrum data segment and a brain electrical activity data segment, and sequentially storing said data segments into a .neg file in binary form according to the above order. The method can store comprehensive test information, flexibly configure the near-infrared and brain electrical measurement information, and realize synchronous storage of near-infrared data and brain electrical data and maintain file version compatibility.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: October 29, 2019
    Inventors: Tianzi Jiang, Nianming Zuo, Xin Zhang, Yujin Zhang, Hao Liu
  • Patent number: 10456570
    Abstract: The present invention relates to subcutaneously implanted graft-port systems, devices and methods for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a flattened plateau-like surface for receiving an access tube. The flat surface may include a tactile or visual guide to assist with placement of the access tube into the tapered seat. Optional valve mechanisms reduce the size and form factor of the implantable graft-port device and seals the conduit of the port closed to physiologic pressures until the valve is opened upon percutaneous insertion of the access tube. The access tube does not pass into the conduit.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: October 29, 2019
    Assignee: PROVIFLO, LLC
    Inventor: Charles David Finch, Jr.
  • Patent number: 10441211
    Abstract: The method of detecting bone fractures using backscattered light makes use of backscattered near infrared (NIR) light to determine if a body part of a patient is healthy, has a bone fracture, or has an edema. An incident beam of near infrared light is generated by a light source, and has both an incident amplitude and an incident phase. The incident beam of NIR light is directed toward the patient's body part, and a backscattered beam of NIR light is received from the body part. The backscattered beam of NIR light has a backscattered amplitude and a backscattered phase. The determination of whether the body part is healthy, has a bone fracture or has an edema is made based on the level of absorption of the incident beam of NIR light and/or based on the amount of scattering, based on the phase difference, of the incident beam of NIR light.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: October 15, 2019
    Inventors: Ali Hajjiah, Ebraheem Sultan, Kawther Al Mejadi, Sara Al Omran, Shemoukh Al Failakawi, Sara Borjaib
  • Patent number: 10433731
    Abstract: There is a need for a compact instrument and microscope that maps the vibration fingerprints of biomolecules and chemicals in a sample such as brain, breast, cervix, and arteries. One can use spontaneous Raman scattering to accomplish this; however, the problem is low scattering efficiency to 10?5. With the availability of continuous wave diode laser at numerous wavelengths from 375 nm-1800 nm for parametric nonlinear difference vibrational mixing to enhance Stimulated Raman process within materials. A seed beam at Raman frequency is used with pump laser beam. In this way one can map in 2D and 3D images of the vibrations associate with disease changes. Scanning a pair of laser beams can map the location of vibrations within cells, smears, membranes, arteries, and tissues of animal and human.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: October 8, 2019
    Inventor: Robert R. Alfano
  • Patent number: 10438346
    Abstract: The present invention relates to methods and devices that may be used to extract spatial frequency information. In one embodiment, the invention provides an instrument configured to extract data using a two-dimensional (2D) Hilbert transform technique, and providing spatial frequency information from a sample. In another embodiment, the invention provides a spatial frequency domain imaging (SFDI) device adapted for demodulation using two or less imaging frames.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: October 8, 2019
    Assignee: The Regents of the University of California
    Inventors: Kyle Nadeau, Anthony J. Durkin, Bruce J. Tromberg
  • Patent number: 10429627
    Abstract: An imaging system can include an optical fiber and a light source for providing optical stimulation to a region of interest along the optical fiber. A camera can capture emission such as fluorescence resulting from the optical stimulation. A cannula configured for implantation into a subject can be configured to direct the emission from the subject. A mating sleeve coupling the cannula to the optical fiber, and configured to support the camera, can include a dichroic mirror to allow the optical stimulation to pass from the optical fiber to the cannula and to redirect the emission from the cannula to the camera.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: October 1, 2019
    Assignee: University of Utah Research Foundation
    Inventors: Rajesh Menon, Ganghun Kim
  • Patent number: 10422749
    Abstract: The disclosed embodiments relate to a system that displays an image of the characteristics of the biological tissue. During operation, the system enables a user to illuminate a measurement location in an area of interest on the biological tissue by manipulating a point measurement probe, wherein the point measurement probe delivers both an excitation beam and an overlapping aiming beam that is visible to a camera. Next, the system obtains fluorescence information from a fluorescence signal emitted from the measurement location in response to the excitation beam. The system then captures an image of the area of interest using the camera and identifies a portion of the image that corresponds to the measurement location by identifying a location illuminated by the aiming beam. Finally, the system generates an overlay image by overlaying the fluorescence information onto the portion of the image that corresponds to the measurement location, and then displays the overlay image to a user.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: September 24, 2019
    Assignee: The Regents of the University of California
    Inventors: Laura Marcu, Dinglong Ma, Julien Bec, Dimitris Gorpas, Diego R. Yankelevich
  • Patent number: 10413232
    Abstract: Systems and methods for discriminating between malignant and benign pigmented skin lesions based on optical analysis using spatial distribution maps, morphological parameters, and additional diagnostic parameters derived from images of tissue lesions. A handheld optical transfer diagnosis device is disclosed capable of capturing a series of reflectance images of a skin lesion at a variety of angles of illumination and observation.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: September 17, 2019
    Assignee: BALTER MEDICAL, AS.
    Inventor: Jakob J. Stamnes
  • Patent number: 10413190
    Abstract: This invention relates to an apparatus and a method for measuring whether organic matter is present or whether or not organisms (cells or tissue) are alive using infrared absorption spectroscopic analysis. The measurement apparatus of the invention includes an infrared light source for radiating infrared rays on a sample, an infrared detection unit for detecting the infrared rays transmitted or reflected from the sample, and a determination unit for identifying an amide infrared absorption peak of the sample using the detected infrared rays and for determining whether organic matter is present or whether organisms are alive or not in the sample using the identified amide infrared absorption peak. In this invention, a reagent is not used, simple measurement is performed, quantification is feasible, and the presence or absence of cells or tissues and changes in the life and death can be consecutively measured for the same sample.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 17, 2019
    Assignee: Hanbat National University Industry-Academic Cooperation Foundation
    Inventor: Sang-Mo Shin
  • Patent number: 10405798
    Abstract: A bio-information detecting apparatus includes: a band member curved in a C-shape, and attached around a neck part of an examinee from a back side of the neck part; and a pair of electrodes for cardiac potential measurement disposed at positions on the band member that come into contact with right and left skin surfaces of the neck part, and in the pair of electrodes, a position of the electrode on the right is located relatively more frontward than a position of the electrode on the left. The bio-information detecting apparatus further includes a substrate to optically measure a blood oxygen saturation for pulse measurement at a position on the band member that comes into contact with the neck part of the examinee, and a pressing force of the substrate against the skin surface of the neck part is 0.96 to 1.21 [N/cm2].
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: September 10, 2019
    Inventors: Hisashi Iizuka, Hirokazu Kikuchi
  • Patent number: 10398233
    Abstract: A furniture system includes a chair having a seat, a backrest coupled to the seat, and a base supporting the backrest and the seat. The furniture system also includes a plurality of sensors and a processor. Each sensor is operable to detect a physical force imparted by a user on the chair, and generate an output signal indicative of the physical force. The processor is coupled to the plurality of sensors, and is operable to receive the output signals generated by the plurality of sensors, and determine, based on at least one of the output signals, a current posture of the user sitting in the chair.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: September 3, 2019
    Assignee: HERMAN MILLER, INC.
    Inventors: Christopher Hoyt, Daniel Rucker, Joseph Doran, Brian Alexander, Adam Daley-Fell
  • Patent number: 10386303
    Abstract: A Raman microscopy imaging device (100) is described, having: a first laser light source (12) for emitting a first laser beam (16) having a first wavelength along a first light path (20); a second laser light source (44) for emitting a second laser beam (18) having a second wavelength, different from the first wavelength, along a second light path (22) physically separated from the first light path (20); a beam combining element (32) for collinearly combining the two laser beams (16, 18) in one shared light path (34) directed onto a sample; a detector (38) for sensing a measured signal on the basis of the two laser beams (16, 18) interacting with the sample; and an evaluation unit (40) for evaluating the measured signal sensed by the detector (38). According to the present invention the first laser light source (12) is embodied as a pulsed source, and the second laser light source (44) as a continuous source.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: August 20, 2019
    Assignee: Leica Microsystems CMS GmbH
    Inventors: Vishnu Vardhan Krishnamachari, Volker Seyfried, William C. Hay
  • Patent number: 10356334
    Abstract: An imaging device may include a first illumination port to output first light having a first illumination distribution at a target to illuminate the target, a second illumination port to output second light having a second illumination distribution at the target to illuminate the target, the second illumination distribution being substantially similar to the first illumination distribution at the target, the second illumination port being spaced apart from the first illumination port, the first and second illumination distributions being simultaneously provided to the target and overlapping at the target. The illumination from the first and second ports may be matched to a same aspect ratio and field of view coverage as the imaging field of view.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: July 16, 2019
    Inventors: Frederick Allen Moore, Anton Walter Lamprecht, Lesley Myron Otsig, Paul Roald Westwick, Muhammad Nasir al-Din bin Zulkafly, Gavin Michael Murray, Adam John Tynan, James Elliott Cameron, Gregory Vincent Browne, Isabelle Fontaine
  • Patent number: 10342432
    Abstract: An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for collecting light from the turbid sample target area, and a processor to analyze the data captured by the sensor to yield scattering and absorption coefficients of the turbid sample. A method comprises illuminating the sample with spatial structured light, collecting light reflected from the sample at a number of wavelengths, illuminating the sample with non-spatial structured light, collecting light reflected from the sample at a number of wavelengths, and combining the measurements of the collected light to obtain the optical properties of the sample and/or the concentration of absorbing or fluorescent molecules. The wavelengths of the spatial and non-spatial light sources are preferably different.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: July 9, 2019
    Inventors: David Cuccia, Amaan Mazhar
  • Patent number: 10327951
    Abstract: Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: June 25, 2019
    Assignee: EXCEL-LENS, INC.
    Inventors: David H. Mordaunt, Kingman Yee
  • Patent number: 10321822
    Abstract: A fundus camera and method of operating the fundus camera are described. The fundus camera includes an image sensor, an eyepiece lens, an illumination source, and an alignment target. The image sensor captures image light of a retina within an eye. The eyepiece lens is disposed to pass the image light of the retina to the image sensor. The illumination source is disposed to direct illumination light onto the retina through the eyepiece lens. The illumination source is further disposed around a first aperture through which the image light of the retina passes from the eyepiece lens to the image sensor. The alignment target is coupled to output an alignment image through the eyepiece lens to the eye and disposed around a second aperture through which the image light of the retina is passed to the image sensor and the illumination light is passed to the eyepiece lens.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: June 18, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Seung Ah Lee, Chinmay George Belthangady, Charles M. Santori
  • Patent number: 10309832
    Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: June 4, 2019
    Assignee: MarqMetrix Inc.
    Inventors: Brian James Marquardt, John Scott Van Vuren
  • Patent number: 10308257
    Abstract: In some examples, a system may generate an alternating current signal to one of a first sensor electrode or a second sensor electrode. For instance, the first sensor electrode may be associated with a seatbelt and located adjacent to a torso of a vehicle operator of a vehicle. Further, the second sensor electrode may be positioned to be contacted by or otherwise proximate to another body part of the vehicle operator, such as at least one of an arm, hand, leg, or foot of the vehicle operator. The system may receive from the other one of the first sensor electrode or the second sensor electrode, a signal indicative of a capacitance, and may determine a respiration rate of the vehicle operator based at least partially on the signal indicative of the capacitance.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: June 4, 2019
    Assignee: Hitachi, Ltd.
    Inventor: Subrata Kumar Kundu
  • Patent number: 10288567
    Abstract: The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific tens used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: May 14, 2019
    Assignee: Cedars-Sinai Medical Center
    Inventors: Pramod Butte, Paul Lapchak, David Scott Kittle
  • Patent number: 10278649
    Abstract: A technique for classifying lesions as malignant or benign is disclosed. The technique can include: cooling an area of skin including a lesion of a patient to initiate a warm-up process; receiving a temporal sequence of thermal images of the area of skin representing a thermal recovery of the area of skin, the temporal sequence of thermal images generated by an infrared camera; generating a temporal profile of the thermal recovery based on the temporal sequence of thermal images; analyzing temporal statistical properties of the temporal profile; determining a malignancy probability that the lesion is malignant based on an analysis of the temporal profile, wherein the determining includes extracting one or more statistical features based on continuous-time stochastic signals in the sequence of thermal images; and classifying the lesion based on the malignancy probability.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: May 7, 2019
    Assignee: STC.UNM
    Inventors: Majeed M. Hayat, Sanjay Krishna, Sebastian Eugenio Godoy, David A. Ramirez
  • Patent number: 10271735
    Abstract: An imaging system for an object such as human or animal tissue applies acoustic vibrations localized in two or three dimensions and simultaneously illuminates the object with an illuminating electromagnetic wave. A transmitter or receiver is provided that has an antenna with at least one coil that surrounds an axis along which at least a portion of the acoustic vibration is output.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: April 30, 2019
    Inventors: David John Edwards, Grahame Edward Faulkner, Ning Zhang, Eleanor Georgina Edwards
  • Patent number: 10264974
    Abstract: Disclosed are methods for imaging lumen-forming structures such as blood vessels using near-infrared fluorescence in the NIR-II region of 1000-1700 nm. The fluorescence is created by excitation of solubilized nano-structures that are delivered to the structures, such as carbon nanotubes, quantum dots or organic molecular fluorophores attached to hydrophilic polymers. These nanostructures fluoresce in the NIR-II region when illuminated through the skin and tissues. Fine anatomical vessel resolution down to ?30 ?m and high temporal resolution up to 5-10 frames per second is obtained for small-vessel imaging with up to 1 cm penetration depth in mouse hind limb, which compares favorably to tomographic imaging modalities such as CT and MRI with much higher spatial and temporal resolution, and compares favorably to scanning microscopic imaging techniques with much deeper penetration.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: April 23, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Guosong Hong, Jerry Chung-yu Lee, Ngan Fong Huang, John P. Cooke, Hongjie Dai
  • Patent number: 10231872
    Abstract: Laser assisted cataract surgery methods and devices utilizing one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may optionally be added onto or into the lens capsule tissue, and the treatment laser wavelength selected to be strongly absorbed by the light absorbing agent. Alternatively, the treatment laser wavelength may be selected to be absorbed or strongly absorbed by the tissue itself, in which case no additional light absorbing agent need be used. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the procedure. The devices may be attached to or integrated with microscopes.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: March 19, 2019
    Assignee: EXCEL-LENS, INC.
    Inventor: David Mordaunt
  • Patent number: 10225449
    Abstract: According to one embodiment, the present invention relates to (1) a sensor system configuration to record multi-level spatial and spectral information for creating high spatial resolution, large coverage, and high spectral resolution (hyperspectral) images, and (2) a multi-level spatial and spectral resolution sharpening method to create high spatial resolution, large coverage hyperspectral images.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: March 5, 2019
    Assignee: University of New Brunswick
    Inventor: Yun Zhang
  • Patent number: 10217891
    Abstract: The present invention includes a method for biomimetic-inspired infrared sensors utilizing a bottom up approach. This method includes providing a sinusoidal alternating electrical field between a preformed electrode gap comprising two gold micro-electrodes. Providing single needles of zinc phosphide crystals optimized for growth conditions using a physical vapour transport. Immobilizing at least one individual zinc phosphide nanowire in the preformed electrode gap using dielectrophoretic manipulation. And, placing and contacting the at least one individual zinc phosphide nanowire in the preformed electrode gap. Two nanowires are combined to form a lambda shape for improved sensing.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 26, 2019
    Inventors: Meir Israelowitz, Herbert Peter von Schroeder, Syed Rizvi, Chris Holm, Christoph Gille, Birgit Weyand, Kerstin Reimers-Fadhlaoui, Peter Vogt, Vicente Muñoz-SanJosé