Abstract: A computer-implemented method for controlling a vehicle. The method monitors one or more characteristics of one or more users within the vehicle, and compares the one or more characteristics of the one or more users with one or more corresponding baseline characteristics of the one or more users. The method further determines, based on the comparison, that a difference between the one or more characteristics and the one or more corresponding baseline characteristics of the one or more users exceeds a threshold value, and performs a controlling action associated with the vehicle, wherein the controlling action may be taking a higher level of autonomous control over the vehicle; varying speed and handling of the vehicle; and overriding the one or more characteristics of the one or more users in order to avoid an accident.

Abstract: A method and a device for determining a degree of thermal hair damage are provided. A method for determining a degree of thermal hair damage includes, during exposure of a hair sample of hair to UV or UV/VIS light, recording a spectrum of at least a portion of the UV or UV/VIS light that has interacted with the hair sample. Further, the method includes comparing at least a portion of the spectrum with a spectroscopic calibration model obtained using UV or UV/VIS spectra and degrees of thermal damage of a plurality of calibration hair samples. Also, the method includes determining the degree of thermal hair damage by using the comparison.

Abstract: A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.

Abstract: A method and a device for performing enhanced thermal digital subtraction angiography comprising infrared video camera, computer cable of subtracting all images produced by tissues having a temperature below a setup point, reconstructing and displaying 2D or 3D images of the received data, performing measurement of the vessels being displayed, conducting data analysis and mathematical calculation of hemodynamic parameters, storing and displaying the images produced. Said device is coupled to embodiments to warm the intravascular injectate, to warm the J-tip guide wire and to warm the intravascular catheter during angiography and during endovascular procedures. Furthermore, the device can be used to perform non-enhanced thermal digital subtraction imaging of part of interest and enhanced thermal digital subtraction imaging for joint, epidural and intrathecal space producing thermal arthrography, epidurography and myelography.

Abstract: An artificial-intelligence decision-making core system with neural network implements asymmetric hidden layers which is constructed by neural network with a dynamic neuron adjusting mechanism via making use of a device with computing unit and storage media, coupled to an independent feedback sub-system which operates a residual-compensation mechanism, thereby the core system can receive various trained data and performs a non-linear analysis process according to the output data derived from the asymmetric hidden layers of an unsupervised neural network, so as to derive individual and applicable decision-making data.

Abstract: A biological information detection apparatus includes: a light source which projects a pattern of near-infrared light onto an object including a living body; an imaging system which includes first photodetector cells detecting light in a near-infrared wavelength range and second photodetector cells detecting light in a visible wavelength range, and generates a first image signal representing a first image, which is an image taken in the near-infrared wavelength range, of the object on which the pattern is projected, and a second image signal representing a second image of the object taken in the visible wavelength range; and a calculator which calculates biological information concerning the living body using at least one selected from the group consisting of the first and second image signals.

Abstract: A diffuse-optical-spectroscopy system and method for scanning human tissue. The system includes: (a) a handheld probe operable to emit electromagnetic radiation at one or more wavelengths corresponding to absorption associated with one or more human-tissue constituents, respectively, the handheld probe being operable to detect received electromagnetic radiation at each of the wavelengths; and (b) a processor operable to produce, in response to the received electromagnetic radiation, one or more cross-sectional images of the human tissue respectively associated with the wavelengths. The handheld probe includes first and second sources for emitting the electromagnetic radiation and one or more sensors for detecting the received electromagnetic radiation. The sensors are aligned along a first axis and face in an outward direction. The first and second sources are aligned along the first axis, face in the outward direction, and are disposed on either side of the sensors.

Abstract: A monitoring system that includes an infrared detector comprising a field of view that detects temperature data from the field of view and provides a signal indicative of at least a detected temperature of a subject. The system includes a tab comprising a tab temperature that is positioned within the field of view such that the infrared detector detects the tab and emits a signal indicative of a detected temperature of the tab. The system includes a temperature sensor secured to the tab that detects the tab temperature and provides a signal indicative of a reference temperature. A control unit is communicatively coupled to the infrared detector and the temperature sensor and computes a net value between the detected temperature of the subject and the detected temperature of the tab. The control unit calculates a core temperature of the subject by combining the net value with the reference temperature.

Abstract: A facial recognition system, comprising: an automatically adjustable camera rig comprising a plurality of movable cameras, wherein the plurality of movable cameras are moved by a camera control platform according to take enrollment images; a first input for receiving images from the automatically adjustable camera rig; a second input for receiving a plurality of images from an comparative input; a first computing memory for storing a machine learning model that includes a three dimensional and a two dimensional comparison between the received first input and the received second input, wherein the comparison uses key facial points to compute a distance between the first input and the second input; and a match output in a case of a distance within a predetermined threshold.

Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity.

Abstract: A cartilage-tissue analysis device includes: an illuminating fiber that emits, from a light-emission surface thereof, laser light coming from a laser light source; two light-collecting fibers that receives scattered light at respective light-receiving surfaces the distances from which to the light-emission surface differ from each other; and detector that detects Raman spectra from the scattered light received by the light-collecting fibers. The cartilage-tissue analysis device is configure to: calculate an intensity ratio between two Raman bands originating from cartilage tissue and subchondral bone tissue, respectively, from each of the two Raman spectra; and evaluate a state of the cartilage tissue by selecting, from among the two Raman spectra, a Raman spectrum the intensity ratio of which is within a prescribed range and that analyzes the selected Raman spectrum, to analyze the selected Raman spectrum.

Abstract: A biological state detecting apparatus which generates biological information of a person, light sources which emit light having a first wavelength and light having a second wavelength, respectively, an imaging device which receives reflected light of the emitted light, a controller which controls the light sources, an arithmetic operator which reads out a first image and a second image from the imaging device and performs an arithmetic operation thereon, and a state estimator which generates the biological information of the person. The arithmetic operator generates a distance image based on the first image and the second image.

Abstract: The present disclosure relates to method for predicting location and depth of abnormal tissue in breast tissue by prediction system. The prediction system predicts location based on 2D thermal image generated based on temperature values and intermediate temperature values. The intermediate temperature values are estimated using triangular and rectangular patterns formed on pre-defined model of breast, thermal conductivity of breast tissue, 2D coordinates on one of triangular and rectangular patterns and temperature values at steady state of breast tissue. The depth is predicted based on 3D thermal image of breast tissue generated using temperature values and intermediate temperature values and error parameter.

Abstract: Embolism treatment devices, systems, and methods are provided. In one embodiment, an embolism treatment system includes a flexible elongate member configured to be positioned within a blood vessel of a patient, the flexible elongate member comprising a distal portion and a proximal portion; an ultrasound imaging component positioned at the distal portion and configured to emit ultrasound energy towards a blood clot within the blood vessel and collect an image signal representative of the blood clot; a treatment component positioned at the distal portion and configured to treat the blood clot; and a flow sensing component positioned at the distal portion and configured to determine a blood flow measurement within the blood vessel associated with the blood clot.

Abstract: An electrosurgical instrument capable of supporting resonance of microwave energy at multiple frequencies. The instrument comprises a coaxial cable and a radiating distal tip portion arranged to receive microwave energy from the coaxial cable. The radiating tip portion consists of a dielectric material having an electrical length selected in conjunction with its dielectric properties at three or more frequencies of microwave energy to support resonance at each frequency. By providing a single device that can effectively couple microwave energy into biological tissue at three or more frequencies, tissue ablation can be performed rapidly with accuracy. The instrument may be used in an apparatus that includes a generator arranged to supply microwave energy at three or more different frequencies.

Abstract: A piecewise progressive continuous calibration method with context coherence is utilized to improve display of virtual content. When a set of frames are rendered to depict a virtual image, the VAR system may identify a location of the virtual content in the frames. The system may convolve a test pattern at the location of the virtual content to generate a calibration frame. The calibration frame is inserted within the set of frames in a manner that is imperceptible to the user.

Abstract: A device for securing and monitoring movement of a catheter includes a film having an adhesive disposed on a body-facing surface for securing the film to a body. The device also includes a base mounted on the film, the base comprising a first portion of a guide channel for receiving the catheter. A cover is coupled to the base via a hinge, the cover comprising a second portion of the guide channel, the cover further comprising a rounded portion extending from a distal end of the cover, wherein in the closed configuration, the catheter is completely enclosed by the rounded portion and the first and second portions of the guide channel. The device also includes a positional shift indicator fixedly attached to the catheter and configured to indicate positional shifts by the catheter within the guide channel.

Abstract: Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can include an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution.

Abstract: The invention relates to a medical inspection apparatus (1), such as a microscope or endoscope, and to a medical inspection method such as microscopy or endoscopy. Visible image data (11) representing a visible-light image (49) and fluorescence image data (12) representing a fluorescent-light image (51) and a pseudocolor (70, 71) are merged to give an improved visual rendition of an object (2) which comprises at least one fluorophore (6) to mark special features of the object (2). This is accomplished in that an image processing unit (18) of the microscope (1) or endoscope is configured to compute a color (ro, go, bo) of an output pixel (54) in the pseudocolor image (53) from at least one pseudocolor (rp, gp, bp), a color (ri, gi, bi) of a first input pixel (50) in the visible-light image (49) and an intensity (f) of a second input pixel (52) in the fluorescent-light image (51).

Abstract: An optical sensor, an optical sensor array, and an apparatus and method for measuring a bio-signal are provided. The optical sensor includes a photodetector, and a light source disposed on the photodetector. The optical sensor is configured to operate the light source in a light source mode, and operate the photodetector in a photodetector mode, based on a control signal.

Abstract: The system may include a setup app that is configured to locate, track and/or analyze activities of living beings in an environment. The system may be configured for determining a temperature of an object in a space, based on infrared (IR) energy data of IR energy from the object, determining location coordinates of the object in the space, comparing the location coordinates of the object to location coordinates of a fixture and determining that the object is a human being, in response to the temperature of the object being within a range, and in response to the location coordinates of the object being distinct from the location coordinates of the fixture.

Abstract: A light sensing method, applied to a light sensing system comprising a light sensor and at least one light source. The light sensor comprises a plurality of light sensing units. The light sensing method comprises: controlling the light sensor to capture images according to the light source; generating an exposure condition according brightness that each of the light sensing units senses, to control all the light sensing units to generate a target brightness distribution according to the exposure condition; and controlling the light sensing units to sense light from the light source according to the exposure condition. The light sensing system can have a better SNR via adjusting the exposure condition for each one of the light sensing units. Such light sensing method can be applied to compute physiological parameters.

Abstract: Some embodiments of the present inventive concept provide a multispectral imaging system including a first light source, the first light source having a first wavelength configured to produce a non-coherent illumination to image a sample; a second coherent light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample simultaneously with the first light source; a camera configured to simultaneously receive information related to the first and second light sources from the sample, wherein light at the first wavelength is configured to image a surface of the sample into the camera and light at the second wavelength is configured to penetrate the sample and provide information related to the penetrated sample to the camera; and a processor configured to combine the received information related to the first and second light sources and generate a synthesized image of the anatomical structure and the physiology of blood flow and

Abstract: Disclosed herein is a two-piece sensor assembly that includes an attachment collar configured to attach to a body surface of a patient and comprising at least one opening, and a skin sensor configured to seat into the at least one opening in the attachment collar. The skin sensor includes at least one radiation source configured to irradiate the body surface with at least one interrogation light, and at least one detector configured to detect at least one response light incident from the direction of the body surface.

Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.

Abstract: An user interaction system for performing interaction with a user based on recognition of a sitting posture of the user includes a posture recognition seat including a posture recognition sensor for recognition the sitting posture of the user, and at least one communication module for communication with an external device, a posture mimicking animated device including a communication module for performing communication with the communication module of the posture recognition seat, wherein the posture mimicking animated device visually mimics the sitting posture of the user or visually or audibly guide the sitting posture of the user, in accordance with state information about the sitting posture of the user determined based on a sensing result obtained by the posture recognition sensor, and a mobile application installed in a communication device possessed by the user, wherein the mobile application receives synchronized information related to the sitting posture of the user via communication with the posture

Abstract: Provided is an imaging system including a light source which emits light in at least a portion of a wavelength band of an excitation wavelength with respect to each of a first fluorescent material emitting fluorescence belonging to a near-infrared wavelength band and a second fluorescent material emitting fluorescence belonging to a visible wavelength band, a first image sensor that detects a first fluorescent image of the target in the near-infrared wavelength band, a second image sensor that detects the second fluorescent image of the target in the visible wavelength band, and optics to direct the first fluorescent image to the first image sensor and the second fluorescent image to the second image sensor. The optics include a dichroic film that directs light of the near-infrared wavelength band into a first optical branch and at least a portion of light of the visible wavelength band into a second optical branch, separate from the first optical branch.

Abstract: A medical instrument is provided and includes a housing and a shaft coupled to the housing. The shaft has a proximal end and a distal end. An end-effector assembly is disposed at the distal end of the shaft. The end-effector assembly includes first and second jaw members. At least one of the first and second jaw members is movable from a first position wherein the first and second jaw members are disposed in spaced relation relative to one another to at least a second position closer to one another wherein the first and second jaw members cooperate to grasp tissue therebetween. The medical instrument also includes one or more light-emitting elements and one or more light-detecting elements configured to generate one or more signals indicative of tissue florescence. The one or more light-emitting elements are adapted to deliver light energy to tissue grasped between the first and second jaw members.

Abstract: A method for increasing accuracy of measurement of body temperature includes a step of collecting an infrared signal to obtain an infrared signal value (step 1), a step of collecting a skin image to obtain a calibrating emissivity (step 2), a step of obtaining a calibrated infrared signal value according to the calibrating emissivity and the infrared signal value obtained in step 1 (step 3), and a step of making a conversion into an actual body temperature (step 4). Accordingly, an actual temperature value of the skin surface can be attained to increase the accuracy of measurement effectively, thereby allowing the measured result to be more close to the real body temperature of a tested target.

Abstract: An imaging apparatus includes: an imaging sensor including a plurality of pixels; a color filter including a plurality of filters arranged to correspond to the pixels; a first light source configured to irradiate a subject with visible light; a second light source configured to irradiate the subject with near-infrared light; a first processor including hardware, the first processor being configured to control an irradiation timing of each of the first light source and the second light source; and a second processor including hardware, the second processor being configured to generate a plurality of pieces of near-infrared image data on different near-infrared regions based on first image data and second image data, the first image data being generated by the imaging sensor by capturing an image of the subject, the second image data being generated by the imaging sensor by capturing an image of the subject.

Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

Abstract: Provided are an endoscope system and a method of operating the same capable of reliably performing focusing even in a case where an observation target is illuminated with light including long-wave light. A movable lens moves in an optical axis direction. A lens drive unit moves the movable lens from a first lens position of the movable lens where an observation target illuminated with short-wave light is focused to a second lens position of the movable lens where the observation target illuminated with long-wave light having a longer wavelength than the short-wave light is focused.

Abstract: The present application discloses a surface-enhanced Raman scattering (SERS)-active photonic crystal fiber (PCF) probe including a biopsy needle in the PCF probe for integrated sample collection and SERS sensing of one or more analytes comprised in the sample. The PCF comprises solid core and a cladding region surrounding the solid core, wherein the cladding region comprises air holes functionalised by metallic nanoparticles. The application also provides a method for detecting one or more analytes using the PCF probe as well as the use of the PCF probe for the detection of one or more analytes.

Abstract: A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.

Abstract: An infrared detector and an infrared sensor including the infrared detector are provided. The infrared detector includes a plurality of quantum dots spaced apart from each other and including a first component, a first semiconductor layer covering the plurality of quantum dots, and a second semiconductor layer covering the first semiconductor layer.

Abstract: A control system having one or more controllers configured to determine physical or psychophysiological (3P) changes of an operator of a vehicle. First and second imaging devices take real-time images of an operator of a vehicle. Then, based on the physical, physiological and/or psychological features extracted from the imaging device data, and a 3P model from historical data the one or more processors also configured to, responsive to the physical, physiological and/or psychological changes of the operator of the vehicle, alert the operator and control the operation of the vehicle.

Abstract: An endoscope system according to the present invention includes: a second illumination unit that emits second illumination light; a first illumination unit that emits, simultaneously with the second illumination light, first illumination light that is light of a different wavelength band from the second illumination light and is for imaging two sets of image information about a subject different depths; an imaging unit that simultaneously images a first illumination image of the subject illuminated with the first illumination light and a second illumination image of the subject illuminated with the second illumination light; a separation processing unit that separates the two sets of image information from the first illumination image; and a separated-image creating unit that processes the second illumination image using the two sets of image information to create separated images.

Abstract: The present invention relates to an imaging device (100) for generating an image of a patient (P), the imaging system (100) comprising: a camera arrangement (10), which is configured to provide a first image information (I1) of the patient (P) using a first wavelength band, and which is configured to provide a second image information (I2) of the patient (P) using a second wavelength band. The first wavelength band and the second set of wavelength band are different; and the first and/or second image information comprises landmark information of landmarks (M) of a patient (P). The landmark information is derived by at least one wavelength band outside the visible spectrum. Further, a data processor (30) is provided, which is configured to generate a fused image (IE) based on the first image information (I1) and the second image information (I2), and which is configured to detect the landmarks (M) in the fused image (IE).

Abstract: Disclosed is an apparatus for observing a tear film on a persons or animals eye. The apparatus comprises an infrared sensitive camera that includes a camera lens system and a computer configured to receive data from the camera, process the data using software and represent the processed data on a display. The camera is configured to measure temporal and spatial changes of thermal radiation from a surface of the eye at a frame rate, a spatial resolution, and a thermal sensitivity that allows the dynamics of the tear film to be visualised. Also disclosed is a method of observing a tear film on an eye of a person or an animal using an apparatus, such as that described above, where the method includes the step of viewing the dynamics of the tear film using the apparatus.

Abstract: The system is configured to locate, track and/or analyze activities of living beings in an environment. The system does not require the input of personal biometric data. The sensor system detects infrared (IR) energy from a living being moving in an environment, determines a temperature of the living being based on IR energy data of the IR energy, projects the temperature onto a grid having sequential pixels, determines serial changes of the temperature in the sequential pixels and determines a trajectory of the living being based on the serial changes of the temperature in the sequential pixels.

Abstract: An eye tracking-based concealed information testing, which includes: presenting images of objects at certain coordinates on a computer display; operating a camera to track eye movements of a human subject observing the display; computing one or more gaze parameters for each of the objects, based on the tracked eye movements and the certain coordinates; and determining that a certain one of the objects is familiar to the human subject based on the gaze parameter. The eye tracking-based concealed information testing is optionally integrated with a short-term memory task, to enhance detection of concealed information.

Abstract: An electronic device, such as a watch, has a housing to which a carrier is attached. The carrier has a first surface interior to the electronic device, and a second surface exterior to the electronic device. A set of electrodes is deposited on the exterior surface of the carrier. An additional electrode is operable to be contacted by a finger of a user of the electronic device while the first electrode is positioned against skin of the user. The additional electrode may be positioned on a user-rotatable crown of the electronic device, on a button of the electronic device, or on another surface of the housing of the electronic device. A processor of the electronic device is operable to determine a biological parameter of the user based on voltages at the electrodes. The biological parameter may be an electrocardiogram.

Abstract: The invention discloses a NIR method for fatty acid content of oilseeds, including: selection of oilseed samples, and analyzing the oilseed samples by an near infrared spectrometer to obtain NIR spectra; preprocessing of NIR spectra and establishment of a NIR spectral database of oilseeds; establishment of a fatty acid database of oilseeds based on gas chromatography; establishment of prediction model of fatty acids in oilseeds; acquiring NIR spectrum of a sample to be tested by the near infrared spectrometer, and importing the preprocessed NIR spectrum into the prediction model of fatty acids to obtain the predicted fatty acid content of the tested sample. The method is simple and rapid to operate and is non-destructive, and the detection time of the sample is greatly shortened and the detection cost is reduced.

Abstract: A method is described for determining a degree of damage to hair, which includes: registering light which is radiated by the hair sample while a hair sample is illuminated with light; based on the registered light, determining first regions of the hair sample which reflect the light with higher interference, and second regions of the hair sample which reflect the light with lower interference; and determining a degree of damage to the hair sample based on the extents of the first regions and of the second regions.

Abstract: A method for displaying information, including receiving measurements, with respect to an invasive probe inside a body of a subject, of probe parameters consisting of a force exerted by the probe on tissue of the subject and temperatures measured by sensors of the probe. The method further includes, responsively to the measurements, displaying in a single map on a display screen a graphical representation of a distribution of the temperatures in a vicinity of the probe and superimposing thereon a vector representation of the force.

Abstract: A system for collecting cannabis and the psychoactive component tetrahydrocannabinol from a sample of exhaled breath is disclosed. Single or multiple exhaled breaths are conditioned by removing contaminants, and regulating flow rate and/or pressure to collect a sample of tetrahydrocannabinol for timely local or remote analysis. The cannabis detection system comprises a containment trap for removing interfering materials from the breath of the subject and a collection component for sampling components of breath introduced into the system through the containment trap for analysis to determine a presence of THC in the breath.

Abstract: A fluctuation-based fluorescence microscopy method, comprising influencing a point-spread function of the imaging of a sample emitting fluorescence radiation using an optical device in dependence on a parameter such that a point emitter is imaged into a representation with two image lobes. The relative positions of the lobes depend on the position of the point emitter relative to the focal plane. Synthetic pixels, smaller than detector pixels, are generated; for each synthetic pixel, pairs of pixel groups are defined among pixels of the detector based on the influencing of the point spread function. Each pair is assigned to an individual value of the parameter. In each frame and for each synthetic pixel, a signal correlation is ascertained and allocated as image brightness to the synthetic pixel for the parameter specification. Subframes for each frame are produced from the synthetic pixels, and a high-resolution sample image is produced from the subframes.

Abstract: The invention relates to a device and an according method for hybrid optoacoustic and ultrasonographic imaging of an object (1), comprising an irradiation unit (2, 3) for irradiating the object (1) with electromagnetic radiation, in particular light, and a transducer unit (4) comprising a plurality of transducer elements (5), the transducer elements (5) being configured to emit ultrasound waves impinging on the object (1) and to detect ultrasound waves which are reflected and/or transmitted by the object (1) upon impinging on the object (1), and to detect ultrasound waves which are generated in the object (1) upon irradiation with electromagnetic radiation, wherein the transducer elements (1) are arranged along a curved line, in particular a concave line, or a curved surface, in particular a concave surface.

Abstract: A method includes generating spectral image data reproducible as one or more spectral images of a plurality of regions of interest in a sample. The method also includes analyzing the spectral image data to identify a plurality of scattering components in the spectral image data, each of the plurality of scattering components being associated with one or more biological properties of the sample. The method also includes identifying a feature of interest in the sample based at least in part on one or more the identified plurality of scattering components.