Infrared Radiation Patents (Class 600/473)
  • Patent number: 10123704
    Abstract: A hybrid system is developed using thermal and electrical impedance imaging methods together. The innovation of the approach relies on the frequency dependence of the tissue's electrical impedance which facilitates the acquisition of multiple thermal images with currents at different frequencies injected to the region of the body under inspection. Proposed method without current application (in passive mode of operation) provides images which are obtained by standard thermal imagers. On the other hand, the application of the electrical current (in active mode of operation) increases the temperature contrast on the body surface depending on the electrical property of tissue. Therefore, the technique while increasing the thermal contrast provides frequency dependent conductivity distribution data which can be used as a basis for the detection of the breast carcinoma. The sensitivity of the technique is increased by an infrared camera with dual band (MWIR/LWIR) imaging capability.
    Type: Grant
    Filed: July 5, 2013
    Date of Patent: November 13, 2018
    Inventors: Nevzat Guneri Gencer, Hamza Feza Carlak, Cengiz Besikci
  • Patent number: 10117705
    Abstract: Methods and apparatus for optically recognizing tissue parameters during an energy-based tissue-sealing procedure involve grasping tissue with a tissue-sealing instrument, illuminating the grasped tissue or tissue adjacent to the grasped tissue with light, analyzing the light that is transmitted, scattered, or reflected by the tissue, and recognizing the tissue based on the result of analyzing the light. The wavelength of the light may be selected so that a vessel is sufficiently recognizable in tissue containing the vessel. A marker may also be introduced into fluid flowing in the vessel to increase the contrast between the vessel and tissue containing the vessel. Analyzing the light includes analyzing the spatial and spectral distribution of light. Analyzing the light may also include forming the light into an image of the illuminated tissue.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: November 6, 2018
    Assignee: COVIDIEN LP
    Inventors: Boris Chernov, Nataliya Chernova, Igoris Misuchenko, Georgy Martsinovskiy, Mikhail Verbitsky
  • Patent number: 10105057
    Abstract: The present invention relates to an apparatus 100 and, a method and a computer program for determining a parameter indicative of a tissue type of an associated tissue 116. In particular, the invention relates to an apparatus 100 comprising a spectrometer 102, which spectrometer comprises a light source 104 and a detector 106, 108 arranged to measure an optical spectrum. This enables determination of a first parameter being indicative of a bile concentration. As the inventors of the present invention have made the insight that bile concentration may serve as a discriminative feature for different tissue types, the apparatus is arranged to determine a second parameter indicative of a tissue type based on a concentration of bile. According to a specific embodiment, the apparatus further comprises an interventional device 112.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: October 23, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Bernardus Hendrikus Wilhelmus Hendriks, Rami Nachabe, Gerhardus Wilhelmus Lucassen, Adrien Emmanuel Desjardins, Theodoor Jacques Marie Ruers
  • Patent number: 10098692
    Abstract: Methods are provided for monitoring and controlling tissue ablation using RF energy delivered by an imaging ablation catheter under direct visualization, using the control and modulation of a set of ablation parameters based on direct optical imaging of the tissue surface via the imaging ablation catheter, where a set of optical image-derived parameters modulates the setting of a subset of Radio Frequency dosing parameters. The ablation dosing algorithms based on image-derived information can be implemented manually or in semi-automated or automated forms.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: October 16, 2018
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: John B. Allison, Jean-Luc Pageard, Brian Pedersen, Celina Escobedo
  • Patent number: 10092449
    Abstract: Systems, methods, and devices used to treat eyelids, meibomian glands, ducts, and surrounding tissue are described herein. In some embodiments, an eye treatment device is disclosed, which includes a scleral shield positionable proximate an inner surface of an eyelid, the scleral shield being made of, or coated with, an energy-absorbing material activated by a light energy, and an energy transducer positionable outside of the eyelid, the energy transducer configured to provide light energy at one or more wavelengths, including a first wavelength selected to heat the energy-absorbing material. Wherein, when the eyelid is positioned between the energy transducer and the scleral shield, the light energy from the energy transducer and the heated energy-absorbing material of the scleral shield conductively heats a target tissue region sufficiently to melt meibum within meibomian glands located within or adjacent to the target tissue region.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: October 9, 2018
    Assignee: Tear Film Innovations, Inc.
    Inventors: Brian S. Kelleher, Kabir Gambhir
  • Patent number: 10092183
    Abstract: Systems and methods for imaging an eye are disclosed. The systems and methods may include at least one plenoptic camera. The systems and methods may include an illumination source with a plurality of lights.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: October 9, 2018
    Assignee: Dr. John Berestka
    Inventor: John Berestka
  • Patent number: 10080527
    Abstract: Systems, methods and devices for reducing noise in health monitoring including monitoring systems, methods and/or devices receiving a health signal and/or having at least one electrode or sensor for health monitoring.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: September 25, 2018
    Assignee: RHYTHM DIAGNOSTIC SYSTEMS, INC.
    Inventors: George Stefan Golda, Daniel Van Zandt Moyer, Mark P. Marriott, Sam Eletr, Bruce O'Neil
  • Patent number: 10041822
    Abstract: A calibration method for a hand-held surgical instrument is disclosed. The hand-held instrument includes a drive motor, a firing rod controlled by the drive motor and having at least one indicator, and a sensor configured to detect the at least one indicator. A microcontroller includes a pulse modulation algorithm stored therein to control the drive motor. The microcontroller executes a calibration algorithm to adjust at least one program coefficient in the pulse modulation algorithm.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: August 7, 2018
    Assignee: Covidien LP
    Inventor: Michael A. Zemlok
  • Patent number: 10034647
    Abstract: A system for the endoscopic X-ray luminescence computed tomographic imaging is provided.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 31, 2018
    Assignee: XIDIAN UNIVERSITY
    Inventors: Jimin Liang, Xueli Chen, Xiaochao Qu, Shouping Zhu, Duofang Chen, Heng Zhao, Jie Tian
  • Patent number: 10013811
    Abstract: The present application discloses a novel algorithm to convert medical hyperspectral images (MHSI) into RGB (RedBlueGreen) images in different medical conditions by making use of the three spectral bands (Red, Green and Blue) of the MHSI and mapping them into Red, Green and Blue components for visualization of hyperspectral images.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: July 3, 2018
    Assignee: Umm-Al-Qura University
    Inventor: Maher I Rajab
  • Patent number: 10004497
    Abstract: A surgical instrument for use by an operator in a surgical procedure includes an elongate shaft, an end effector extending from the elongate shaft, and a control system. The end effector is articulatable relative to the elongate shaft between a home state position and an articulated position. The control system includes a processor and a memory coupled to the processor to store program instructions. The processor can alert the operator when the end effector reaches the home state position from the articulated position.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: June 26, 2018
    Assignee: Ethicon LLC
    Inventors: Mark D. Overmyer, Brett E. Swensgard, Shane R. Adams, Thomas W. Lytle, IV, Richard L. Leimbach, Frederick E. Shelton, IV, Kevin L. Houser
  • Patent number: 9986177
    Abstract: A method for capturing and consolidating multi-spectral image data for regions of interest using one or more spectral boost mechanisms or techniques is disclosed. A first multi-spectral or hyperspectral workflow comprising time-stamped two-dimensional pixelated images of a region of interest is obtained by a first computer-enabled imaging device. Each of the images corresponds to image data captured for a respective frequency band of a plurality of frequency bands. First meta data is associated with the images of the first workflow and includes: a plurality of first positions and first orientations of the first imaging device indicating first positional and orientation data for the first imaging device, and indications of a respective frequency band for each of the images of the first workflow. A consolidated multi-spectral workflow for the region of interest is generated, which includes spectrally and spatially consolidating the images of the first workflow using the first meta data.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: May 29, 2018
    Assignee: GALILEO GROUP, INC.
    Inventors: Donald Michael Barnes, James Michael Grichnik, Zhihong Pan
  • Patent number: 9980650
    Abstract: A remote photoplethysmography system includes a filter (10) for application to a detection unit. The filter further includes a first filter area (11) configured to transmit light (A) at a first wavelength and a second filter area (12) configured to transmit light (D) at a second wavelength. The detection unit (22) detects radiation received from the first filter area and from the second filter area of the filter. An analysis unit (6) determines the vital sign information of the subject from the detected radiation from the first filter area and from the second filter area.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: May 29, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Rick Bezemer
  • Patent number: 9968788
    Abstract: In general, the disclosure is directed toward an implantable medical device that includes a plurality of sensor modules that are implanted within a patient. The sensor modules may cooperate with each other to coordinate the timing for performance of one or more sensor actions across the modules when making a measurement. Example measurements include tissue perfusion measurements, oxygen sensing measurements, sonomicrometry measurements, and pressure measurements. The coordination of the sensor modules may be controlled by a signal that is transmitted from a host controller to the sensor modules via a bus. In some examples, the bus may have two wires that transmit both timing information and data information to the sensor modules. The signal may be a signal that is substantially periodic, such as a pulsed signal. In additional examples, the signal may supply operating power and timing information to the sensor modules.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: May 15, 2018
    Assignee: Medtronic, Inc.
    Inventors: Robert Michael Ecker, Kaustubh R. Patil, John Robert Hamilton, James D. Reinke, Timothy Davis
  • Patent number: 9949918
    Abstract: The present invention provides compositions comprising extracts of Jojoba (Simmondsia chinensis) in a polar solvent that are effective in promoting the barrier functions of the skin, useful for improving skin integrity, health and appearance and as anti-aging agent.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: April 24, 2018
    Assignee: IBR—Israeli Biotechnology Research Ltd.
    Inventors: Etienne Soudant, Ilana Kachko-Chernetsky, Fabien Havas, Olga Ben-Chitrit, Lea Von Oppen-Bezalel, Inon Perry, Alex Aliluiko
  • Patent number: 9940740
    Abstract: The present invention aims to provide a refractometer that can satisfactorily observe an actual state of measurement light during a measurement with low cost. A graph 311 showing detection intensity of measurement light detected by a detector and a captured image 312 by a camera are displayed on one display screen 301 in real time. This configuration eliminates the need to separately provide a display unit for displaying the captured image 312 by the camera, thereby reducing cost. In addition, the actual state of measurement light can satisfactorily be observed during the measurement through the confirmation of the captured image 312 by the camera displayed on one display screen 301 along with the graph 311 in real time.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: April 10, 2018
    Assignee: SHIMADZU CORPORATION
    Inventor: Nobuhiko Sawayanagi
  • Patent number: 9936084
    Abstract: A system includes a wrist computer and a portable video camera. The wrist computer acquires physical activity data measured by a sensor device, generates a time marker on the basis of the physical activity data, and transmits the time marker to the portable video camera according to a predefined wireless communication protocol. The portable video camera is configured to record video data, encode the video data into a video data file, and store the received time marker as meta data in the video file.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: April 3, 2018
    Assignee: Polar Electro Oy
    Inventors: Mika Erkkila, Niclas Granqvist
  • Patent number: 9913606
    Abstract: Embodiments of the present disclosure disclose a method and system for determining health condition of a subject. First step of the method comprises receiving, by a computing unit, a first oxygen saturation level and a second oxygen saturation level from at least two sensors placed on the subject. Second step of the method comprises determining cerebral extraction of oxygen using the first and second oxygen saturation levels. Third step of the method comprises comparing the cerebral extraction of oxygen with a threshold level. Fourth step of the method comprises identifying a mental fatigue level of the subject based on outcome of the comparison, wherein the mental fatigue level indicates the health condition of the subject.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 13, 2018
    Assignee: Wipro Limited
    Inventors: Satish Prasad Rath, Upendra Suddamalla
  • Patent number: 9907696
    Abstract: A motion-compensated cutting system includes a hand-held tool body, and an actuator connected to the tool body. A shaft of the actuator is movable relative to the tool body so that a distal end of a cutting implement attached to the shaft is axially movable relative to the tool body. An optical coherence tomography system includes an optical fiber with a distal end fixed relative to the distal end of the cutting implement. The system includes a control unit that can determine a position of the distal end of the cutting implement relative to a reference surface based on input from the optical coherence tomography system. The control unit can control the cutting implement to compensate for relative motion between the tool body and the reference surface, and can maintain a predetermined depth of the distal end of the cutting implement with respect to the reference surface.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: March 6, 2018
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Jin U. Kang, Peter L. Gehlbach
  • Patent number: 9906718
    Abstract: The subject invention includes a biomimetic integrated optical sensor system, based on the integration of a wide field-of-view (WFOV) miniature staring multi-aperture compound eye with a high-speed, low-cost, polarization and spectral selective liquid crystal (LC) filter array, a MWIR focal plane array (FPA), and a neural network processor.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: February 27, 2018
    Assignee: Luminit LLC
    Inventors: Winston X. Xia, Fedor I. Dimov
  • Patent number: 9892513
    Abstract: Methods and systems for characterizing tissue of a subject are disclosed. The method includes receiving a time series of fluorescence images of the tissue of the subject wherein the images define a plurality of calculation regions, generating a plurality of time-intensity curves for the plurality of calculation regions, creating a set of parameter values for each calculation region, generating a total rank value for each calculation region by comparing the sets of parameter values, and converting the total rank value into a ranking map image. Also disclosed are methods and systems for characterizing a wound in tissue by generating a wound index value.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: February 13, 2018
    Assignee: Novadaq Technologies ULC
    Inventors: Lina Gurevich, Jorgen Walle-Jensen
  • Patent number: 9883803
    Abstract: An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for collecting light from the turbid sample target area, and a processor to analyze the data captured by the sensor to yield scattering and absorption coefficients of the turbid sample. A method comprises illuminating the sample with spatial structured light, collecting light reflected from the sample at a number of wavelengths, illuminating the sample with non-spatial structured light, collecting light reflected from the sample at a number of wavelengths, and combining the measurements of the collected light to obtain the optical properties of the sample and/or the concentration of absorbing or fluorescent molecules. The wavelengths of the spatial and non-spatial light sources are preferably different.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: February 6, 2018
    Assignee: MODULATED IMAGING, INC.
    Inventors: David Cuccia, Amaan Mazhar
  • Patent number: 9871950
    Abstract: Provided is an image forming apparatus that forms a layer of at least one type of scattering material. The image forming apparatus is configured to obtain subsurface scattering characteristic data indicating the subsurface scattering characteristic of a reproducing target, and determine the laminated structure of the layer of the scattering material based on the subsurface scattering characteristic data. The image forming apparatus is configured to then form an image corresponding to the layer of the scattering material based on the determined laminated structure of the layer of the scattering material.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: January 16, 2018
    Assignee: Canon Kabuhshiki Kaisha
    Inventors: Kimitaka Arai, Hideki Kubo
  • Patent number: 9848812
    Abstract: fNIRS may be used in real time or near-real time to detect the mental state of individuals. Phase measurement can be applied to drive an adaptive filter for the removal of motion artifacts in real time or near-real time. In this manner, the application of fNIRS may be extended to practical non-laboratory environments. For example, the mental state of an operator of a vehicle may be monitored, and alerts may be issued and/or an autopilot may be engaged when the mental state of the operator indicates that the operator is inattentive.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: December 26, 2017
    Assignee: The United States of America as Represented by the Administrator of National Aeronautics and Space Administration
    Inventors: Angela Harrivel, Tristan Hearn
  • Patent number: 9839413
    Abstract: A protective guide for protecting a cell extraction device used during a Pap smear. An access tunnel receives the cell extraction device and allows for access and movement of the cell extraction device. A protective chamber covers and protects the head of the cell extraction device as the cell extraction device is being removed and inserted from the patient's vagina. A protective guide connector attaches the protective guide to an imaging transducer. After inserted into the patient's vagina, the location of the patient's cervix is determined by utilization of the imaging transducer. Once the cervix is located the cell extraction device is pushed outward from the protective chamber so that the cell extraction device head contacts the cervix and then removes cells from the cervix. The cell extraction device head is then pulled back into the protective chamber and the protective guide is removed from the patient's vagina.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: December 12, 2017
    Inventors: Matthew D Millard, Imran Jawaid, Winston L Alexis
  • Patent number: 9820886
    Abstract: Laser assisted cataract surgery methods and devices utilizing one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may optionally be added onto or into the lens capsule tissue, and the treatment laser wavelength selected to be strongly absorbed by the light absorbing agent. Alternatively, the treatment laser wavelength may be selected to be absorbed or strongly absorbed by the tissue itself, in which case no additional light absorbing agent need be used. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the procedure. The devices may be attached to or integrated with microscopes.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: November 21, 2017
    Assignee: EXCEL-LENS, INC.
    Inventor: David Mordaunt
  • Patent number: 9823189
    Abstract: In an embodiment of the present disclosure, an optical method for determining morphological parameters and physiological properties of tissue is presented. The method includes using reflectance measurements from a tissue area for a plurality of wavelengths, using a bio-optical model, using radiative transfer modeling and using a non-linear inversion procedure.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: November 21, 2017
    Assignee: Balter, AS.
    Inventors: Jakob J. Stamnes, Knut Stamnes, Lu Zhao, Boerge Hamre, Gennady Ryzhikov, Marina Biryulina, Endre R. Sommersten, Kristian Pagh Nielsen, Johan E. Moan
  • Patent number: 9820638
    Abstract: Embodiments of the invention are directed medical devices for illuminating and viewing a patient's internal body portion. The device may include an elongated flexible tube including a distal end and a proximal end. The tube defines a channel extending from the proximal end to an aperture at the distal end. An illumination device is housed within the channel and configured to emit a distally directed path of light. A light source is provided at the distal end of the flexible tube and configured to emit a laterally directed path of light. In one embodiment the light source is a organic light emitting diode.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: November 21, 2017
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Eric Cheng
  • Patent number: 9795303
    Abstract: Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above overtime. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: October 24, 2017
    Assignee: Hypermed Imaging, Inc.
    Inventors: Svetlana V. Panasyuk, Jenny Freeman, Alexander Panasyuk
  • Patent number: 9772275
    Abstract: Disclosed herein is a measuring probe and an arrangement for measuring spectral absorption, preferably in the infrared. Furthermore, the invention relates to a method for spectroscopically measuring absorption. The measuring probe may comprise a cutting apparatus configured to cut a slice or respectively flap off of a sample to be measured; a measuring gap configured to accommodate the sample slice; an optical window element for coupling measuring light into, or respectively out of the measuring gap; and an end reflector designed and arranged to reflect the measuring light propagated through the measuring gap back into the measuring gap. The arrangement for measuring spectral absorption may comprise the measuring probe, a light source and an apparatus for the spectral analysis of the measuring light coupled out of the measuring gap.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: September 26, 2017
    Assignee: Universität Stuttgart
    Inventors: Klaus Koerner, Christof Pruss, Alois Herkommer, Wolfgang Osten, Daniel Claus
  • Patent number: 9772224
    Abstract: A component measurement apparatus includes: a sensor module that receives reflected light and outputs a signal corresponding to light intensity of the reflected light; a calibration plate that outputs first reflected light to the sensor module, the first reflected light being used for comparing the light intensity of the reflected light; and a calibration unit that switches the input reflected light to the sensor module between the second reflected light reflected at a measured portion, and the first reflected light.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: September 26, 2017
    Assignee: Seiko Epson Corporation
    Inventors: Hideto Ishiguro, Tsukasa Eguchi, Hitoshi Tsuchiya, Megumu Ito
  • Patent number: 9737201
    Abstract: A device and method for example operating an in vivo imaging device wherein the illumination is operated at a certain rate or range of rates, and images are transmitted from the device.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: August 22, 2017
    Assignee: GIVEN IMAGING LTD.
    Inventors: Dov Avni, Arkady Glukhovsky
  • Patent number: 9717448
    Abstract: Various embodiments of methods and systems for continuous transdermal monitoring (“CTM”) are disclosed. One exemplary embodiment of a continuous transdermal monitoring system comprises a sensor package. The sensor package may include a pulse oximetry sensor having a plurality of light detectors arranged as an array. One exemplary method for continuous transdermal monitoring begins by positioning a pulse oximetry sensor system, similar to the system described immediately above, adjacent to a target tissue segment. Then, the method continues by detecting a light reflected by the target tissue segment. Then, the method continues by transmitting a pulse oximetry reading(s), based at least in part on the light reflected by the target tissue segment, of the target tissue segment. Then, the method continues by analyzing the pulse oximetry reading(s).
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: August 1, 2017
    Inventors: James Tyler Frix, Andrew Johnson, James Mitchell Frix, Robert Andrew Taylor
  • Patent number: 9709485
    Abstract: A new technique which uses a pump-probe methodology to place a molecule into one or more excited rotational and/or vibrational states. By evaluating spectral changes due to at least one discrete frequency of pump photons a multi-dimensional characterization of the molecule's excited state energy level results. This multi-dimensional characterization typically involves evaluating the changes between excited and unexcited state measurements. The differential nature of the evaluation makes the technique self-referencing and solves problems common to many spectroscopic techniques. The multi-dimensionality of the technique provides high specificity and immunity to interferents. The preferred embodiments involve excitation by using photons suited to pumping the rotational states and evaluating the effects by probing the energy levels of one of more vibrational states.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: July 18, 2017
    Assignee: Kestrel Corporation
    Inventors: Eugene W Butler, Timothy M Stratman, Boyd V Hunter, Paul Harrison, Jason M Cox
  • Patent number: 9693693
    Abstract: A non-contact, passive method for measurement of arterial pulse from areas such as the major superficial arteries of the body through analysis of thermal IR images acquired by passive thermal IR imaging sensors, and through the modeling of the pulsatile nature of the blood flow and arterial pulse propagation in the circulatory system. The method is automatic and does not need operator input. The output waveform readily contains the information on heart rate, cardiac interbeat intervals, heart-rate variability and other features inherent in arterial pulse.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: July 4, 2017
    Assignee: University of Louisville Research Foundation
    Inventors: Aly A. Farag, Sergey Y. Chekmenev
  • Patent number: 9687158
    Abstract: Provided is a fluorescence observation apparatus including a light source; a section generating a fluorescence image of an object; a section generating a reference image of the object; a section generating a corrected image in which emphasized are pixels of the reference image corresponding to pixels each having luminance value equal to or more than a first threshold value in the fluorescence image; a display unit displaying the reference image or the corrected image; a bleeding state determining section determining whether or not a bleeding region of the subject detected based on the reference image is more than a predetermined range; and a section switching between displaying the reference image on the display unit if the determining section determines that the region is not more than the range, and displaying the corrected on the image display if the determining section determines that the region is more than the range.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: June 27, 2017
    Assignee: OLYMPUS CORPORATION
    Inventor: Toshiaki Watanabe
  • Patent number: 9681810
    Abstract: A fluorescent image acquisition and projection apparatus for real-time visualization of an invisible fluorescent signal is provided. The apparatus visualizes an invisible fluorescent signal generated from a target object (a tissue of a living body, a cell of a living body, or the like) by using a photodetection unit and a projector in real time. The apparatus directly projects a visualized fluorescent signal onto a region of the target object where the invisible fluorescent signal is generated, thereby enabling users to determine and confirm the generation location of the fluorescence with the naked eye.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: June 20, 2017
    Assignee: Korea Photonics Technology Institute
    Inventors: Byeong-Il Lee, In-Hee Shin, Jae-Seok Park, Joo-Beom Eom, Hyung-Ju Park, Seok-Ki Kim
  • Patent number: 9668656
    Abstract: The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: June 6, 2017
    Assignee: SOTERA WIRELESS, INC.
    Inventors: Matt Banet, Marshal Dhillon, Devin McCombie
  • Patent number: 9655563
    Abstract: For therapy response assessment, texture features are input for machine learning a classifier and for using a machine learnt classifier. Rather than or in addition to using formula-based texture features, data driven texture features are derived from training images. Such data driven texture features are independent analysis features, such as features from independent subspace analysis. The texture features may be used to predict the outcome of therapy based on a few number of or even one scan of the patient.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: May 23, 2017
    Assignee: Siemens Healthcare GmbH
    Inventors: David Liu, Shaohua Kevin Zhou, Martin Kramer, Michael Sühling, Christian Tietjen, Grzegorz Soza, Andreas Wimmer
  • Patent number: 9636096
    Abstract: A retractor system with a closed loop control includes a retractor having one or more sensors, which measure parameters associated with a retracted tissue. The system further includes a positioning mechanism connected to the retractor and a controller which receives feedback signals from the sensors. Based on the feedback signals from the sensors, the retractor is actuated by the positioning mechanism so that the tissue can be retracted while maintaining the parameters associated with the retracted tissue above a threshold level or within a desired range. Another retractor system includes a retractor with a force sensor and at least one additional sensor, which can be used without a closed loop control arrangement.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: May 2, 2017
    Assignee: ViOptix, Inc.
    Inventors: Larry C. Heaton, II, Alex Keller, Robert E. Lash, Jimmy Jian-min Mao
  • Patent number: 9638638
    Abstract: Disclosed herein is a system (10) for measuring light induced transmission or reflection changes, in particular due to stimulated Raman emission. The system comprises a first light source (12) for generating a first light signal having a first wavelength, a second light source (14) for generating a second light signal having a second wavelength, an optical assembly (16) for superposing said first and second light signals at a sample location (18), and a detection means (24) for detecting a transmitted or reflected light signal, in particular a stimulated Raman signal caused by a Raman-active medium when located at said sample location. Here in at least one of the first and second light sources (12, 14) is one or both of actively controllable to emit a time controlled light pattern or operated substantially in CW mode and provided with an extra cavity modulation means (64) for generating a time controlled light pattern.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: May 2, 2017
    Assignee: Ludwig-Maximilians-Universität München
    Inventors: Robert Alexander Huber, Thomas Klein, Wolfgang Wieser, Sebastian Karpf, Matthias Eibl
  • Patent number: 9603508
    Abstract: A method for capturing and displaying endoscopic maps is disclosed generally comprising providing an endoscope with a view vector that pivots relative to the longitudinal axis of the endoscope, programming a scan trajectory along which the view vector moves relative to the longitudinal axis of the endoscope to provide a predefined sequence of views of a surface, and capturing a sequence of images corresponding to the predefined sequence of views as the view vector moves along that scan trajectory. A set of configuration coordinates is associated with each of the captured images, and the images and the coordinates associated therewith are used to create a map of the interior surface that is larger than the view attending the view vector.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: March 28, 2017
    Assignee: Karl Storz Imaging, Inc.
    Inventors: Eric Lawrence Hale, Hans David Hoeg, Nathan Jon Schara
  • Patent number: 9588045
    Abstract: The invention relates to a method and a microscope for generating a microscopic image, wherein a) the sample is illuminated in each case by the microscope lens using the TIRF method; and b) the sample is illuminated in a structured fashion in different displacement positions of the structure. The sample light of the method according to a) and b) is detected in each case for generating an image of at least once sample region, wherein the sample images generated according to a) and b) are set off against one another, preferably multiplied, and the result is stored for generating a new sample image.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: March 7, 2017
    Assignee: Carl Zeiss Microscopy GmbH
    Inventors: Ingo Kleppe, Yauheni Novikau
  • Patent number: 9582890
    Abstract: Embodiments segment received image data. The received image data may include pixels that have multiple channels of intensity values. The image data is decomposed into albedo and shading components. This may be accomplished using a minimization that enforces a relationship between albedo, shading, and intensity values. The minimization may also include an albedo regularizer to infer albedo in part based on chromaticity and albedo of surrounding pixels. Superpixels are generated based on contiguous regions of pixels having similar image data across channels. These superpixels are then merged based in part on the determined albedo and shading components as well as based on the image data. The channels of image data may include infrared image data used to modify visible channels of the image to create pseudo-image data, which may be used in place of image data for albedo-shading decomposition, superpixel generation, or superpixel merging.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: February 28, 2017
    Assignee: Ricoh Company, LTD.
    Inventors: Mithun Das Gupta, Srinidhi Srinivasa
  • Patent number: 9572529
    Abstract: Surgical devices and methods for utilizing optical coherence tomography (OCT) to monitor and control tissue sealing are disclosed. The surgical device includes an end effector assembly that includes first and second jaw members that are movable between a first, spaced-apart position and a second proximate position. An OCT system, at least a portion of which is incorporated into the end effector assembly, is configured to sense properties of the tissue, e.g., the structural density of the tissue, disposed between the first and second jaw members. A tissue-sealing energy source may be disposed within at least one of the jaw members and may provide tissue-sealing energy to tissue disposed between the jaw members. A controller, which is coupled to the OCT system and the tissue-sealing energy source, controls the tissue-sealing energy generated by the tissue-sealing energy source based on the properties of the tissue sensed by the OCT system.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: February 21, 2017
    Assignee: COVIDIEN LP
    Inventors: Cassandra Latimer, William H. Nau, Jr.
  • Patent number: 9558499
    Abstract: A method for assessing a pre-cognitive emotional response from a test subject, using responses obtained during the first moments of brain activity after presentation of a stimulus, includes exposing the test subject to a visual stimulus for between approximately 500 milliseconds and approximately 1 second, and receiving an input from the subject while the subject is exposed to the visual stimulus or within approximately 300 milliseconds after the subject is first exposed to the stimulus. The method further includes storing, in response to receiving the input, a user response that identifies one of a plurality of emotional reactions that is associated with the visual stimulus. Each of the exposing, receiving, and storing acts is repeated for a plurality of visual stimuli. The method further includes determining, based on each of the stored user responses, one or more dominant emotional characteristics of the subject.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: January 31, 2017
    Assignee: The Forbes Consulting Group, LLC
    Inventor: David L. Forbes
  • Patent number: 9522240
    Abstract: A visualization apparatus for the vein according to the present disclosure includes a near-infrared ray irradiating unit for irradiating near-infrared rays below the skin of a target area, an infrared camera unit for photographing the target area, an image processing unit for receiving and processing image information of a portion below the skin of the target area, photographed by the infrared camera unit, and providing the processed image information to a display device, and a display device located near the target area to display the image information provided from the image processing unit.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: December 20, 2016
    Assignee: Korea Institute Of Science And Technology
    Inventors: Deukhee Lee, Se Hyung Park, Sung Hwan Lim, Sangjun Lee
  • Patent number: 9486196
    Abstract: A retractor system includes a retractor with an oximeter sensor at its tip and a force sensor coupled to the retractor. The retractor system also includes a system unit which can send signals to and receive signals from the oximeter sensor via optical fibers. The oximeter sensor measures oxygen saturation of a tissue being refracted by the retractor, and the force sensor measures an amount of force that is applied to the retracted tissue by the tip of the retractor. Another retractor system has a closed loop control arrangement with a positioning mechanism which moves the retractor based on measurements of the sensors.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: November 8, 2016
    Assignee: ViOptix, Inc.
    Inventors: Larry C. Heaton, II, Alex Keller, Robert E. Lash, Jimmy Jian-min Mao
  • Patent number: 9439651
    Abstract: A method for encrypted authentication of interchangeable parts of a surgical instrument includes providing a surgical end effector at a distal end of a handle of the surgical instrument and electrically connecting an authentication controller within the handle to a receiving portion of the end effector. An interchangeable part is removably placed at the receiving portion. The interchangeable part is authenticated with the authentication controller when the interchangeable part is seated in the end effector.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: September 13, 2016
    Assignee: Ethicon Endo-Surgery, LLC
    Inventors: Kevin W. Smith, Thomas O. Bales, Jr., Derek Dee Deville, Carlos Rivera, Matthew A. Palmer
  • Patent number: 9414797
    Abstract: A mammography CT system is disclosed which includes an X-ray generator; and a first radiator-detector system. A contrast medium, including an opacifying element including an absorption peak in a first energy range, is useable for tomographic imaging of a female breast of a patient. After filtering, the X-rays with a prespecified tube voltage that form at an anode, are configured to emit an X-ray spectrum having a second energy range, wherein the radiator-detector system is configured to acquire a plurality of circumferential projections around the breast. The first energy range is a part of the second energy range and the second energy range includes an upper limit of less than 70 keV and a lower limit of greater than 20 keV. A corresponding method for generating tomographic mammography CT images is also disclosed.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: August 16, 2016
    Assignees: Siemens Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Thomas Flohr, Gregor Jost, Rüdiger Lawaczeck, Hubertus Pietsch, Bernhard Schmidt