Abstract: A blood pressure monitor equipped with a cardiovascular health condition monitoring module includes: a blood pressure measurement device measuring a user's blood pressure signal; a host including a blood pressure monitor microprocessor that processes blood pressure correlated signal; a control panel equipped to the host and configured to control blood pressure measured by the blood pressure monitor and heart rhythm analysis; a first display device displaying blood pressure result; and a second display device displaying heart rhythm analysis from the cardiovascular health condition monitoring module.

Abstract: An implantable medical device system includes an implantable cardioverter defibrillator (ICD) for detecting and treating ventricular tachycardia (VT). The ICD includes a sensing module for sensing a cardiac signal from available cardiac signal sensing vectors. A control module generates morphology templates of the cardiac signals for multiple patient postures for each of the available sensing vectors and determines a set of posture-independent template features. An unknown cardiac rhythm is classified in response to comparing features of a cardiac signal received during the unknown rhythm to the set of posture-independent features.

Abstract: Embodiments of a testing method suitable for diabetic persons to optimize their administered insulin dosage comprise collecting one or more sampling sets of biomarker data, wherein each sampling set comprises a sufficient plurality of non-adverse sampling instances and wherein each sampling instance comprises an acceptable biomarker reading at a single point in time recorded upon compliance with adherence criteria, determining a biomarker sampling parameter from each sampling set, comparing the biomarker sampling parameter to a target biomarker range, calculating an insulin adjustment parameter associated with the biomarker sampling parameter if the biomarker sampling parameter falls outside the target biomarker range, adjusting the insulin dosage by the insulin adjustment parameter if the biomarker sampling parameter falls outside the target biomarker range and if the insulin dosage does not exceed maximum dosage, and exiting the testing method if the adjusted insulin dosage is optimized.

Abstract: The present invention provides techniques for measuring one or more parameters of a subject using a probe having an optical assembly configured and operable for applying optical measurements to a measurement location in a subject and generating optical measured data indicative thereof comprising at least one of pulsatile and occlusion measurements, a pressure system configured and operable for controllably applying pressure to the subject in the vicinity of the measurement location and measuring pressure inside the pressure system and generating pressure data indicative thereof, and a control system configured and operable for receiving and processing the pressure data to identify whether the optical measured data is valid, and for processing the valid optical measured data and determining at least one relation between the valid optical measured data and the corresponding pressure data indicative of at least one parameter of the subject.

Abstract: An activity state information detecting device includes: a pulse wave measuring section that measures pulse wave information of a user; a body motion measuring section that measures body motion information of the user; and a processing section that performs a calculation process of activity state information of the user, in which the processing section performs a mode switching process between a first mode for performing the calculation process of the activity state information based on the body motion information and a second mode for performing the calculation process of the activity state information based on the pulse wave information.

Abstract: A system and method includes reception of a hemodynamic signal, reception of a cardiac impedance signal, identification of a first peak and a second peak of the cardiac impedance signal, identification of a first portion of the hemodynamic signal based on the first peak and a second portion of the hemodynamic signal based on the second peak, and calculation of a cardiac characteristic based on the first portion and the second portion of the hemodynamic signal.

Abstract: Medical devices and methods for providing breathing therapy (e.g., for treating heart failure, hypertension, etc.) may determine at least the inspiration phase of one or more breathing cycles based on the monitored physiological parameters and control delivery of a plurality of breathing therapy sessions (e.g., each of the breathing therapy sessions may be provided during a defined time period). Further, each of the plurality of breathing therapy sessions may include delivering stimulation after the start of the inspiration phase of each of a plurality of breathing cycles to prolong diaphragm contraction during the breathing cycle.

Abstract: A device can estimate the heart rate of an active user by using a physiological model to refine a “direct” measurement of the user's heart rate obtained using a pulse sensor. The physiological model can be based on heart rate response to activity and can be informed by context information, such as the user's current activity and/or intensity level as well as user-specific parameters such as age, gender, general fitness level, previous heart rate measurements, etc. The physiological model can be used to predict a heart rate, and the prediction can be used to assess or improve the direct measurement.

Abstract: The described physiology sensor is worn on a single finger to capture one or more different physiological signals and has a sensor body including first and second raised mounds, protruding from its surface and being longitudinally spaced-apart such as to define a transverse air gap therebetween. The mounds each retain electrodes which abut palmar surfaces of the single finger. The sensor also has one or more physiological sensing devices housed within the body, including a skin conductance sensing device. The sensor can also have at least one of a temperature sensing device, and a photoplethysmography sensing device. A processor is housed within the body and communicates with the electrodes and the sensing devices to apply an electrical excitation thereto, and to process the physiological measurements.

Abstract: The present invention extends to methods, systems, and computer program products for providing a matching system for correlating accelerometer data to known movements. Data representing known movements can be obtained and stored in a database such as by processing and storing accelerometer data obtained from one or more accelerometers worn by a user while performing a particular movement. The accelerometer data obtained from a particular movement can be processed to generate a feature set descriptive of the accelerations associated with a particular movement or series of movements.

Abstract: A method to identify feature points associated with the heart valve movement, heart contraction or cardiac hemodynamics is revealed. The mechanocardiography (MCG) is a technology that makes use of vibrational waveforms acquired using at least one gravity sensor attached on one of the four heart valve auscultation sites on the body surface. The data of the electrocardiography (ECG) is recorded simultaneously with the MCG. The feature points are identified by comparing P, R and T points of synchronized ECG with the MCG spectrum. By the time sequences and amplitudes of the feature points, the method provides additional clinical information of cardiac cycle abnormalities for diagnosis.

Abstract: A wearable device is provided. The wearable device includes a photon sensor, a processor, and an output unit. The photon sensor senses light reflected from a specific region and transforms the sensed light to a plurality of electric-signal components. The processor receives the electric-signal components sensed within a period to form a dimensional sensing signal. The processor extracts a feature of a waveform of the dimensional sensing signal and determines whether a predetermined heart condition of the object is present according to the feature of the waveform of the dimensional sensing signal to generate a determination signal. The output unit is coupled to the processor. The output unit receives the determination signal and generates an alarm signal according to the determination signal.

Abstract: Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a photoplethysmographic measurement of blood in a portion of subsurface vasculature. A plurality of samples of the photoplethysmographic signal are obtained and a frequency spectrum determined based on a first set of the plurality of samples. A frequency is determined based on a maximum frequency component of the frequency spectrum. Further, a confidence level of the determined frequency of the maximum frequency component is determined based on the magnitude of the maximum frequency component and the overall energy in the frequency spectrum. A pulse rate is then determined by updating a predicted pulse rate of a second, earlier set of the plurality of samples based on the frequency of the maximum frequency component and the determined confidence level.

Abstract: A method for quantifying, during pacemapping, a comparison of a BSPM of interest to a pace site BSPM. The method may include receiving at a computing device a plurality of ECG signals from an acquisition system. The pace site BSPM may be calculated using the plurality of ECG signals. The BSPM of interest may be compared to the pace site BSPM, by: retrieving the BSPM of interest from memory accessible by the computing device; and, calculating one or more comparison metrics for the BSPM of interest as compared to the pace site BSPM. An indication of similarity between the BSPM of interest and the pace site BSPM based on the comparison metric calculated may be displayed on a user interface in communication with the computing device.

Abstract: Systems and methods for detecting a worsening of patient's heart failure condition based, at least in part, on an increasing trend in a representative rapid shallow breathing index (RSBI) value over multiple days. The RSBI value may be a minimum RSBI, and more particularly may be a minimum RSBI value determined for an afternoon portion of each of the multiple days. The minimum RSBI value measured during an afternoon portion of the day may be more sensitive to changes in a patient's respiration, particularly when a patient is expected to be more active, and thus, may more readily exhibit an increasing trend when patient's heart failure is in decline.

Abstract: Oral engagement assemblies and methods of using the oral engagement assemblies are provided. In a general aspect, the oral engagement assembly includes a mouthpiece having a handle and a support attached to the handle. A diagnostic receptacle is insertable into the mouth-piece to form the oral engagement assembly. One or more diagnostic sensors can be fixedly or releasably inserted into the diagnostic receptacle. Kits useful for making the oral engagement assemblies and using such oral engagement assemblies for diagnosing a condition or disease in the animal are also provided.

Abstract: Discussed generally herein are methods and devices including or providing a patch system that can help in diagnosing a medical condition and/or provide therapy to a user. A body-area network can include a plurality of communicatively coupled patches that communicate with an intermediate device. The intermediate device can provide data representative of a biological parameter monitored by the patches to proper personnel, such as for diagnosis and/or response.

Abstract: A wearable electronic device, comprising a heart rate sensor to determine a heart rate of the user, a motion sensor to detect motion of a user, the motion sensor operated in an initial calibration phase during which the heart rate sensor is detecting the heart rate of the user, and the motion sensor is detecting the motion of the user, the calibration phase being used to compute a correspondence between motion of the user and the heart rate of the user, the motion sensor being operated in a low power phase during which the heart rate sensor is powered down, and a processor configured to run a heart rate estimation module configured to calculate an estimated heart rate of the user based upon the motion of the user and the correspondence between the heart rate of the user and the motion of the user determined in the calibration phase.

Abstract: A renal denervation system includes an ablation catheter and an inflation balloon. The renal denervation catheter is insertable into a renal artery to perform a renal denervation procedure. The inflation balloon is inflatable within the renal artery, wherein one of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure.

Abstract: Methods, systems, and apparatus for detecting the seizure in a patient using a medical device. The determination is performed by collecting cardiac data; determining valid heart beats suitable for seizure detection from the cardiac data; calculating heart rate data of interest from the valid heart beats; and identifying a seizure event from the heart rate data. The medical device may then take a responsive action, such as warning, logging the time of the seizure, computing and storing one or more seizure severity indices, and/or treating the seizure.

Abstract: A method and system for determining anaerobic threshold intensity (AnT) of a user in a freely performed physical exercise. A physiological response of a user is measured by heart rate and measured heart rate values are recorded as heart rate data. An external workload values are recorded and are each associated with one measured heart rate values to form a plurality of data points. The data points are filtered to form accepted data points, which are classified within a plurality of heart rate segments representing a heart rate within an anaerobic threshold (AnT) of the user. A data point with highest probability is stored for each segment. A first probability factor for each accepted data point is calculated. The calculated first probability factor is compared to a stored probability factor in each segment, and the higher probability factor is retained. AnT is calculated using the stored probabilities in each segment.

Abstract: An exercise information detecting apparatus of the present invention includes a heartbeat sensor which detects heartbeat data of a human body including a waveform signal, an exercise status detecting section which detects exercise data regarding an exercise status of the human body, an exercise status judging section which judges a change of the exercise status of the human body based on the exercise data detected by the exercise status detecting section, and a heart rate calculating section which removes, as a noise component, an invalid peak from among a plurality of peaks included in the waveform signal of the heartbeat data based on the change of the exercise status of the human body judged by the exercise status judging section.

Abstract: An automated assessment of a patient's peripheral vascular condition includes using a pulse oximeter to generate at least a perfusion index relative to a limb or digit of the patient. Pressure is applied to the limb or digit, and while increasing or decreasing the pressure, a change in the perfusion index is determined. The change is indicative of a cessation of blood flow or a return of blood flow in the limb or digit. A systolic blood pressure is thereafter determined based on the pressure applied at the time of cessation of blood flow or the return of blood flow in the limb or digit. Using a pulse oximeter to generate a perfusion index may include transmitting light into the limb or digit, detecting light that was transmitted into tissue in the limb or digit, and calculating the perfusion index based on the light transmitted through the tissue.

Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.

Abstract: Various embodiments relate to a method, apparatus, system, and a computer program product for suppressing an oscillatory signal Sosc. In the method a composite signal S comprising said Sosc and a modulating signal Smod are provided and the S is high pass filtered to produce estimates of the Sosc and the Smod, wherein the estimate of the Sosc comprises first oscillations during a first state of the modulating signal and second oscillations during a second state of the modulating signal. A first bin associated with said first state and a second bin associated with said second state are defined and assigned for said first oscillation and the second bin for said second oscillation according to a state defined from the estimate of the Smod. A first average waveform for said first oscillations and a second average waveform for said second oscillations are formed and used to suppress the Sosc signal from the composite signal S.

Abstract: The invention provides systems and methods for monitoring the wellbeing of a fetus by the non-invasive detection and analysis of fetal cardiac activity data, utilizing a plurality of acoustic sensors.

Abstract: Systems and methods are described herein for assisting a user in evaluation of cardiac therapy. The systems and methods may monitor electrical activity of a patient using external electrode apparatus to provide baseline cardiac information and therapy cardiac information and determine whether the cardiac pacing, or therapy, location is acceptable. If the cardiac pacing, or therapy, location is unacceptable, location information representative of a location that may more effective may be generated based on the therapy cardiac information.

Abstract: Systems and methods described herein relate to a sleep diagnostic system including a mattress assembly, a plurality of sensors, data acquisition circuitry, an input device, a sleep processor, and a display device. The mattress assembly may have a sleeping surface, and the plurality of sensors may be disposed within the mattress assembly below the sleeping surface. The sensors are configured to measure at least one sleep condition and output data signals indicative of the sleep condition. The sleep processor receives signals from both the sensors and one or more other input devices, and determines a sleep characteristic based upon these received signals. The display device, which includes circuitry and a graphical user interface, receives the sleep characteristic from the sleep processor and displays it to the user.

Abstract: The disclosure relates to systems and methods for cardiac rhythm management. In some cases, a system may include a pulse generator for generating pacing pulses for stimulating a heart of a patient; a memory; and a sensor configured to sense a response to a unwanted stimulation and to produce a corresponding sensor signal. A processing circuit may receive the sensor signal for a time after one or more pacing pulses, and may derive a time-frequency representation of the sensor signal based on the received sensor signal. The processing circuit may use the time-frequency representation of the sensor signal to help identify unwanted stimulation. Once unwanted stimulation is detected, the processing circuit may change the pacing pulses to help reduce or eliminate the unwanted stimulation.

Abstract: An infusion pump assembly includes a reservoir assembly configured to contain an infusible fluid. A motor assembly is configured to act upon the reservoir assembly and dispense at least a portion of the infusible fluid contained within the reservoir assembly. Processing logic is configured to control the motor assembly. The processing logic includes a primary microprocessor configured to execute one or more primary applications written in a first computer language; and a safety microprocessor configured to execute one or more safety applications written in a second computer language.

Abstract: An implantable sensor module and medical device includes a housing having an inner shell having a thickness extending between an inner wall and an outer wall and an outer layer, wherein the inner shell and the outer layer form a substantially flat portion. A shoulder extends adjacent to a diaphragm to extend the outer layer laterally away from a central medial line extending between edges of the diaphragm. A recess portion is formed between the diaphragm and an inner side of the outer layer, and an over-fill channel is formed by the outer layer extending through the outer layer from an opening formed at the outer wall to an opening formed along the inner side of the outer layer extending along the substantially flat portion.

Abstract: A method and an apparatus for obtaining information on a cardiovascular system beat by beat and continuously which are based exclusively on measurements between two limbs and effected with a pair of distal electrodes on each limb. The measurement is made by causing an alternating current to flow between one electrode of each limb and measuring the potential difference between the other two electrodes, one also on each limb. This potential difference has a low frequency component which is an electrocardiogram (ECG) and another component having a frequency of the injected alternating current and from which an impedance plethysmogram (IPG) is extracted. The cardiovascular information is determined by measuring the time interval between any predefined characteristic element of the ECG and one of the IPG.

Abstract: A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion.

Abstract: Systems and techniques for remote medical monitoring. In one implementation, a method includes monitoring a first medical condition of an individual, the monitoring being initiated remotely by a monitoring service, receiving a query relating to a second medical condition of the individual, transmitting a response to the query to the monitoring service, receiving a prompt from the monitoring service, and transmitting a response to the prompt to the monitoring service. The query is received from the monitoring service. The prompt is designed to provoke a particular action.

Abstract: The present disclosure includes a medical monitoring hub as the center of monitoring for a monitored patient. The hub includes configurable medical ports and serial ports for communicating with other medical devices in the patient's proximity. Moreover, the hub communicates with a portable patient monitor. The monitor, when docked with the hub provides display graphics different from when undocked, the display graphics including anatomical information. The hub assembles the often vast amount of electronic medical data, associates it with the monitored patient, and in some embodiments, communicates the data to the patient's medical records.

Abstract: The invention provides systems and methods for monitoring the wellbeing of a fetus by the non-invasive detection and analysis of fetal cardiac electrical activity data.

Abstract: A method provides supervision which includes providing a plurality of information channels for communicating information to the service provider and the user and integrating the information channels to provide access to supervisory functionality for supervising the information channels of the plurality of information channels by way of a single portal. The method provides access to audio/visual functionality, to information record functionality, to diagnostic functionality, to action functionality and to administrative functionality. All functionalities are accessed by way of a portal whereby the portal has access to the functionalities simultaneously. A single accessing of the portal by the user permits the user to gain access to all of the functionalities simultaneously in accordance with the single accessing. The portal can be a web portal. Each of the functionalities is accessed by way of a respective information channel of a plurality of information channels.

Abstract: An exercise detection apparatus determines body movements based on data detected by a detection unit, judges movement states for each body movement based on data detected by the detection unit, corrects the movement states based on a predetermined rule, calculates an exercise state of a user based on a result of the judgment, and stores the calculated exercise state in a storage unit. Accordingly, it is possible to provide an exercise detection apparatus capable of reducing erroneous judgments of the exercise states of the user.

Abstract: A renal denervation system includes an ablation catheter and an inflation balloon. The renal denervation catheter is insertable into a renal artery to perform a renal denervation procedure. The inflation balloon is inflatable within the renal artery, wherein one of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure.

Abstract: A remote patient monitoring system provides patient physiological data and alerts/alarms from a main patient monitor to a remote patient monitor worn by a medical professional. The medical professional is alerted as to physiological data of the monitored patient, and provided alerts or alarms when predetermined levels are reached. The medical professional is able to reset the alert or alarms at the remote patient monitor.

Abstract: A method includes pressurizing a cuff of a blood pressure measurement device that is wrapped around a measurement site of a patient, measuring the patient's blood pressure and pulse period during and before depressurization of the cuff, calculating a threshold value range of the pulse period based on data of a past measured pulse period of the patient, determining whether the measured pulse period is within the threshold value range of the past measured pulse period, if the measured pulse period is determined to be within the threshold value range of the past measured pulse period both during and before depressurization, displaying that the patient was in the rest condition, and if the measured pulse period is determined not to be within the threshold value range of the past measured pulse period either during or before depressurization, displaying that the patient was in the unrest condition.

Abstract: A medication confirmation method and apparatus. The method of an embodiment of the invention includes the steps of capturing one or more video sequences of a user administering medication, storing the captured one or more video sequences, and comparing at least one of the stored video sequences with a corresponding one or more prerecorded video sequences to confirm that the user has properly administered the medication.

Abstract: Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point.

Abstract: A modular holder or patch is described that may be used with or as part of a wireless physiological sensing device. The wireless physiological sensing device may include a holder or patch, first and second electrodes, and an electronics package that may be removably coupled with the holder or patch and which may be in electrical contact with the first and second electrodes. The electronics package may include a housing, a wireless transceiver and electronic circuitry configured to process signals received via the first and second electrodes and the wireless transceiver.

Abstract: A renal denervation system includes an ablation catheter and an inflation balloon. The renal denervation catheter is insertable into a renal artery to perform a renal denervation procedure. The inflation balloon is inflatable within the renal artery, wherein one of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure.

Abstract: The present invention relates to a system (1) and method for automatically monitoring the movement activity of a fetus. In order to provide a simple and reliable technique for monitoring the movement activity of a fetus, a method of automatically monitoring the movement activity of a fetus is suggested, the method comprising the steps of: detecting (200) the overall movements of a pregnant female, said overall movements comprising movements of the pregnant female and movements of the fetus; detecting at least one second physiological signal (26) of the pregnant female; and—determining (300) the movement activity of the fetus by analyzing the detected overall movements of the pregnant female, analyzing the at least one second physiological signal (26) of the pregnant female, and discriminating movements of the pregnant female from movements of the fetus depending on the analyzing results.

Abstract: Specific embodiments of the present invention determine a range of a physiologic property, for each of a plurality of periods of time, and monitor changes in the patient's heart disease based on changes in the range. Other embodiments determine a minimum of a physiologic property, for each of a plurality of periods of time, and monitor changes in the patient's heart disease based on changes in the minimum. Still other embodiments determine a maximum of the physiologic property, for each of a plurality of periods of time, and monitor changes in the patient's heart disease based on changes in the maximum.

Abstract: The invention provides a system and method of providing a user with specialized patient information comprising: uploading, storing, requesting, receiving, and displaying cardiological patient information for a patient. The display of the cardiological information is configured to optimal care to be provided to a patient.

Abstract: A male coupler for a guidewire, the guidewire having a hollow walled tube, the male coupler comprising a connector section, coupled with the guidewire, a portion of the connector section having a diameter smaller than the diameter of the hollow tube, at least one conducting ring coupled with the connector section where the diameter of the connector section is smaller the diameter of the guidewire, wherein the diameter of connector section and the at least one conducting ring substantially equals the diameter of the guidewire.

Abstract: The disclosure pertains to a perfusion system that is easy to set-up, use and monitor during a bypass procedure. In some embodiments, the disclosure pertains to a perfusion system in which at least some of the disposable components used with the perfusion system are configured to be able to communicate set-up and/or operational parameters to the perfusion system in order to unlock further functionality within the perfusion system.