Cardiovascular Patents (Class 600/481)
  • Patent number: 11419554
    Abstract: The invention relates to an electric motor furniture drive for sleeping or reclining furniture, comprising a number of adjusting motors (7, 8) for moving at least one movable furniture component relative to an additional furniture component by means of an electric motor and comprising a manual operation unit (10) for operating the adjusting motors (7, 8). The electric motor furniture drive is characterized in that at least one sensor (12) is provided for detecting vibrations and/or sound, said sensor being coupleable to the sleeping furniture, and an analyzing unit is provided which is connected to the at least one sensor (12). The analyzing unit is designed to process and analyze the signals of the at least one sensor (12) and detect physiological parameters of a person using the sleeping or reclining furniture.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 23, 2022
    Assignee: Dewertokin Technology Group Co., Ltd
    Inventors: Karsten Gehrke, Armin Hille, Steffen Loley, Alexander Tews
  • Patent number: 11419553
    Abstract: The invention relates to an analyzing unit (9?) for connecting to at least one sensor (12) which can be coupled to sleeping or reclining furniture in order to detect vibrations, movement, and/or sound. The analyzing unit (9?) is designed to process and analyze the signals of the at least one sensor (12) and detect physiological parameters (P) of a person using the sleeping or reclining furniture, and the analyzing unit (9?) is designed to transmit data to or exchange data with at least one external component. The invention further relates to a method for analyzing signals of at least one such sensor (12) and to sleeping or reclining furniture, in particular a bed (1), comprising at least one such sensor (12).
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 23, 2022
    Assignee: Dewertokin Technology Group Co., Ltd
    Inventors: Karsten Gehrke, Armin Hille, Steffen Loley, Alexander Tews
  • Patent number: 11412941
    Abstract: A system and method for calibration a system of determining blood pressure based on pulse wave transit time.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 16, 2022
    Assignee: ETROG SYSTEMS LTD.
    Inventor: Eyal Dov Vardi
  • Patent number: 11406273
    Abstract: We disclose a system and method for estimating values of hemodynamic parameters of a subject, by calibrating arterial pressure during one time and tracking arterial pressure at another time.
    Type: Grant
    Filed: December 22, 2018
    Date of Patent: August 9, 2022
    Assignee: Sensifree Ltd.
    Inventors: Ilan Barak, Eran Agmon, Roi Klein, Nadav Neuberger, Alexei Nomazov
  • Patent number: 11357410
    Abstract: A method for measuring blood pressure of a subject is described herein. In an implementation, the method includes obtaining a plurality of photoplethysmogram (PPG) features associated with the subject. The method further includes ascertaining one or more latent parameters associated with the subject based on the plurality of PPG features and a reference model, wherein the reference model indicates a correlation between the plurality of PPG features and the one or more latent parameters. Further, blood pressure of the subject is determined based on the one or more latent parameters and the plurality of PPG features.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: June 14, 2022
    Inventors: Rohan Banerjee, Anirban Dutta Choudhury, Aniruddha Sinha
  • Patent number: 11317868
    Abstract: A multimodal intravascular analysis uses a structural intravascular analysis modality to compensate for a chemical analysis modality. Examples of structural analysis are IVUS, OCT, including optical coherence domain Reflectometry (OCDR) and optical frequency domain imaging (OFDI), and/or sonar rangefinding. Examples of chemical or functional analysis are optical, NIR, Raman, fluorescence and spectroscopy, thermography and reflectometry. In one example, the structural analysis is used to characterize the environment structurally, such as catheter head-vessel wall distance. This information is then used to select from two or more algorithms which are depth specific (e.g. shallow vs. deep), to achieve improved accuracy in the chemical or functional analysis.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: May 3, 2022
    Assignee: Infraredx, Inc.
    Inventors: Jay D. Caplan, Huwei Tan
  • Patent number: 11311276
    Abstract: An ultrasonic diagnostic apparatus includes an image generating unit configured to generate a plurality of different ultrasound image data items from reception signals corresponding to a plurality of different steering angles, on the basis of the reception signals which an ultrasound probe has generated on the basis of reflected ultrasonic waves received from a reflecting surface of a subject body by transmitting ultrasonic waves at the plurality of different steering angles, and a regression estimate generating unit configured to perform regression analysis on the basis of the different steering angles and the ultrasound image data items, and generate regression estimates which are weighting values on the basis of the result of the regression analysis, and an image synthesis unit configured to perform weighting on the plurality of ultrasound image data items on the basis of the regression estimates, and synthesize them, thereby generating synthetic image data.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: April 26, 2022
    Assignee: KONICA MINOLTA, INC.
    Inventor: Jo Shikama
  • Patent number: 11311196
    Abstract: A method, device, and system for evaluating a vessel of a patient, and in particular the hemodynamic impact of a stenosis within the vessel of a patient. Proximal and distal pressure measurements are made using first and second instrument while the first instrument is moved longitudinally through the vessel from a first position to a second position and the second instrument remains in a fixed longitudinal position within the vessel. A series of pressure ratio values are calculated, and a pressure ratio curve is generated. One or more stepped change in the pressure ratio curve are then identified and/or located using an Automatic Step Detection (ASD) process and/or algorithm.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: April 26, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Wenguang Li, Qian Li, Justin Michael Lerman, David Burgess
  • Patent number: 11285303
    Abstract: A balloon dilation assembly configured to be used for performing balloon valvuloplasty in order to dilate a stenotic heart valve, in particular a stenotic aortic valve. The assembly comprises at least three outer balloons (12), (13), (14) evenly arranged in a circle around a central balloon (11) and fixed to the central balloon, and comprises a further outer balloon (15) which is shorter in length compared with balloons (11), (12), (13), (14) and which is not fixed to the central balloon, whereby each balloon has a separate filling tube (1), (2), (3), (4), (5) used for inflating each balloon separately, characterized in that the short outer balloon (15) is equipped with a sensing and/or stimulation system comprising an electrical pole (21).
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: March 29, 2022
    Inventor: Peter Osypka
  • Patent number: 11275557
    Abstract: First sensor data may be acquired from a first galvanic skin response sensor monitoring a first user. Second sensor data may be acquired from a second galvanic skin response sensor monitoring a second user. At least one programmable processor may generate a compatibility score between the first user and the second user. The generating may include executing a compatibility algorithm to generate the compatibility score based at least on a comparison of at least one type of response contained in the first sensor data and the second sensor data. A client device may generate an electronic indication of the compatibility score.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: March 15, 2022
    Assignee: ONTOLEAD, INC.
    Inventors: Firoozeh Motamedi, Shahrokh Yadegari
  • Patent number: 11219375
    Abstract: An electronic device includes a processor and memory, wherein the memory stores instructions that, when executed by the processor, control the electronic device to: determine a pulse arrival time (PAT) value, a heart rate (HR) value, and a pulse transit time (PTT) value from the second data, calculate a first blood pressure value (BP1) and a second blood pressure value (BP2) by applying the determined values to pulse wave velocity (PWV) algorithms of Equations 1 and 2, wherein BP1?a1PAT+b1HR+c1 . . . Equation 1, BP2?a2 ln(PTT)+b2 . . .
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: January 11, 2022
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Donghyun Lee, Sunok Jung, Seunghwan Shin
  • Patent number: 11216942
    Abstract: A method and a system for detecting and analyzing a mucosa of a digestive tract are provided. The method includes detecting reply signals from the mucosa of the digestive tract within a depth range, acquiring 2D vascular images by performing a vascular enhancement on the reply signals, constructing a 3D vascular contrasting image of at least part of the mucosa of the digestive tract within the depth range by recombining at least part of the 2D vascular images, and reconstructing a 3D vascular contrasting projection image by performing a projection process to the 3D vascular contrasting image, and defining a stage of the mucosa of the digestive tract within the depth range according to the 3D vascular contrasting projection image, the 3D vascular contrasting image, the 2D vascular images, and vessel morphologies shown therein.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: January 4, 2022
    Assignee: NATIONAL YANG-MING UNIVERSITY
    Inventors: Wen-Chuan Kuo, Ping-Hsien Chen, Chien-Hsien Wu
  • Patent number: 11210790
    Abstract: A system and method for predicting an outcome specific signal (OSS) in test subject images. The method includes detecting the OSS in image data from outcome and control subjects; extracting a volumetric space containing the detected OSS and dividing the extracted volumetric space into a first set of sub-regions; determining a set of image features for the first set of sub-regions; determining a global feature set (GFS) by averaging the set of image features; utilizing a machine learning algorithm to select a subset of discriminant GFS to determine a best signal model (BSM) that distinguishes the outcome and control subjects; extracting volumetric space containing the target anatomy in test subject images and dividing the extracted volumetric space into a second set of sub-regions; and determining the subset of discriminant GFS at each of the second set of sub-regions, and using them in the BSM to generate the predicted OSS.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: December 28, 2021
    Assignee: 4QIMAGING, LLC
    Inventor: Jose G. Tamez-Pena
  • Patent number: 11206994
    Abstract: A wearable health monitoring device is disclosed. The device includes an attachment feature configured to engage with an attachment feature of an alignment element that is to be worn on the skin of a person, An RF front-end including a semiconductor substrate, at least one transmit antenna configured to transmit radio waves below the skin surface of the person, and a two-dimensional array of receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves, wherein the semiconductor substrate includes circuits configured to generate signals in response to the received radio waves, a digital baseband system configured to generate digital data in response to the signals, wherein the digital data is indicative of a health parameter of the person, and a communications interface configured to transmit the digital data generated by the digital baseband system from the wearable health monitoring device.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: December 28, 2021
    Assignee: Movano Inc.
    Inventor: Michael A. Leabman
  • Patent number: 11154215
    Abstract: There is provided a method that includes receiving pulse-oximetry measurements (SpO2) of a patient's peripheral arterial blood oxygen saturation during a first time period, and receiving breathing samples of the patient. The method further includes determining, using breathing samples of the patient, oxygen partial pressure measurements (PAO2) and carbon dioxide partial pressure measurements (PACO2) from exhaled air of the patient during a steady-state breathing of the patient during the first time period.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: October 26, 2021
    Assignee: Medipines Corporation
    Inventors: Steve Lee, John B. West
  • Patent number: 11134858
    Abstract: A method of locating a source of vibrational cardiac energy within a human, includes acquiring time synchronized vibrational cardiac data noninvasively from a surface of the human's body with at least three transducer channels. A time-to-frequency transformation is performed on the vibrational cardiac data to obtain a sequence of heart cycle ensemble averaged power spectral density (PSD) estimates. A feature is identified in the PSD estimates. A vernier band (VB) in frequency is established for the feature. The VB portion of the PSI) estimates that correspond to the feature are processed to obtain a vibrational energy intensity level estimate at a spatial location within the human's body. A metric of clinical significance is obtained from the strength of the estimated vibration intensity within a VB and at a location relative to a background noise level.
    Type: Grant
    Filed: August 4, 2018
    Date of Patent: October 5, 2021
    Assignee: PHONOFLOW MEDICAL, LLC
    Inventors: Norman Lee Owsley, Ralph Walter Zaorski
  • Patent number: 11109973
    Abstract: Steady flow hydrodynamic performance testing is performed on a valved prosthesis mounted in a test conduit. The system is configured with prescribed test condition inputs into control software. Upon test initiation, a steady flow pump is activated and automatically adjusts its flow based on the software logic to meet the prescribed first test condition. During forward flow pressure drop testing, the flow pump is automatically adjusted to achieve and hold a particular flow rate. During back flow leakage testing, the steady flow pump is automatically adjusted to achieve and hold a particular differential pressure across the test prosthesis while a flow rate of the leakage flow is measured. After a first test condition has been achieved, the system control software then automatically adjusts the pump flow rate to meet a second test condition. This process then continues until all conditions set by software inputs are evaluated.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: September 7, 2021
    Assignee: Biomedical Device Consultants and Laboratories of Colorado, LLC
    Inventors: Benjamin McCloskey, Craig Weinberg
  • Patent number: 11109829
    Abstract: A medical image diagnostic apparatus according to an embodiment includes an estimation unit, an extraction unit, and a specifying unit. The estimation unit estimates a position of a plaque in a blood vessel based on data of CT images constituting a time series, with the blood vessel being enhanced by a contrast medium. The extraction unit extracts regions constituting the blood vessel from the CT images. The specifying unit specifies stress values respectively corresponding to the regions based on a moving displacement due to cardiac pulsation in each of the regions, and specifies an exfoliation risk of the plaque based on an index indicating hardness of the plaque and the stress value in the region corresponding to the position of the plaque.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: September 7, 2021
    Assignee: Canon Medical Systems Corporation
    Inventors: Hideaki Ishii, Satoshi Wakai, Kazumasa Arakita, Takuma Igarashi, Yasuko Fujisawa, Shigeo Kaminaga, Kenji Hirohata, Junichiro Ooga
  • Patent number: 11089978
    Abstract: A detection apparatus and a method are provided for detecting a respiratory movement of a patient. The detection apparatus includes at least two metallic U-shaped signal coupling elements that are interleaved so that between the signal coupling elements arises at least one coupling point at which a signal may be transferred between the two signal coupling elements. Analysis electronics are configured to detect a change in a received signal produced in a second of the signal coupling elements that is acting as a receiver in the near-field region of the first signal coupling elements as a result of a signal given for one of the signal coupling elements that is acting as a transmitter being coupled into the second of the signal coupling elements, which change indicates the respiratory movement.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: August 17, 2021
    Assignee: Siemens Healthcare GmbH
    Inventor: Sebastian Martius
  • Patent number: 11069064
    Abstract: A method and a system for modelling a human heart based on a plurality of emission tomography images representing concentrations of a tracer that has been injected at a specific time is presented. The method comprising: extracting time activity curves of a tracer that has been injected for a plurality of pixels and/or voxels; identifying first-pass peaks of the time activity curves corresponding to an arrival time of the injected tracer at the corresponding pixel/voxel; defining a model comprising at least two portions of the heart; and arranging the at least two portions in relation to each other by comparing the arrival times of the first-pass peaks. The method and model may be used to obtain an estimate of the volume of the left or right atrium of the human heart.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: July 20, 2021
    Assignee: MEDTRACE PHARMA A/S
    Inventors: Jens Sørensen, Hendrik Johannes Harms
  • Patent number: 11056233
    Abstract: A controller-based apparatus for diagnosis and treatment of a subject with acquired brain injury and dysfunction. Various embodiments of the invention described herein recognize that different body postures affect the autonomic nervous system differently, and therefore various external stimuli may have different therapeutic efficacies when a patient or subject is in each body posture. Postures, such as walking, sitting, standing, prone and supine, have different effects on the autonomic nervous system, and therefore some stimuli have different physiological efficacies while a patient or subject is in a given body posture. Disclosed embodiments of the present invention leverage this relationship to provide a controller-based apparatus that determines a combination of posture and stimulus that has optimal therapeutic effect, while minimizing health practitioner involvement.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: July 6, 2021
    Inventor: Victor M. Pedro
  • Patent number: 11000189
    Abstract: Computer implemented methods, systems and devices are provided to monitor for potential heart failure (HF). Cardiac activity (CA) data is obtained and filtered to obtain respiration data indicative of a respiration pattern. The respiration data is analyzed to determine one or more respiration characteristics of interest (COI) that are recorded along with collection time information to form an HF monitoring log. Additionally or alternatively, the CA data is analyzed to detect an event of interest. The cardiac activity data is filtered to obtain respiration data indicative of a respiration pattern, and the respiration data is analyzed for respiration induced under detection of the event of interest from the CA data.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: May 11, 2021
    Assignee: PACESETTER, INC.
    Inventors: Stephanie C. Sun, Xiaoyi Min, Alan B. Vogel, Fujian Qu, Stuart Rosenberg
  • Patent number: 10980430
    Abstract: In one embodiment of the invention, a cuff-less blood pressure measuring system is disclosed including cuff-less blood pressure scanner with a vital signs signal processor having an adaptive blood pressure model. A machine learning process is further disclosed to tune the adaptive blood pressure model of the cuff-less blood pressure measuring system to the user.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: April 20, 2021
    Assignee: HEALTHY.IO LTD.
    Inventors: Piotr Przybyszewski, Eunseog Youn, Walter De Brouwer, Brian G. La Plume, Babak Aghazadeh, Maxim Akhterov
  • Patent number: 10966617
    Abstract: Techniques exist for measuring local blood velocity of flow rate waveforms in, for example, mammalian vascular segments. A method and system for deriving information on disease in vascular segments, for example mean pressure, drop in mean pressure and/or hydraulic resistance, from such measured waveforms is described. The waveforms can, for example, be measured non-invasively using Doppler ultrasound or magnetic resonance techniques. Form factors (Vff, Pff) for the velocity waveform and the central arterial pressure are determined. Stenosis may be detected by detecting changes e.g in Vff/Pff.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: April 6, 2021
    Assignee: Bluedop Medical Ltd.
    Inventors: David H. King, Mohammed Al-Qaisi
  • Patent number: 10929334
    Abstract: A subscriber station for a serial bus system are provided. The subscriber station includes a message creating device for creating a message to be transmitted serially via a bus of the bus system for at least one further subscriber station of the bus system, so that the message has a first time segment and a second time segment, and a transceiver device for serially sending the message to the bus in such a way that data in the first time segment are sent with a slower data rate than in the second time segment, the transceiver device having in the second time segment at least at times an exclusive, collision-free access to the bus, the message creating device to insert an identification number into the first time segment and to begin the second time segment at the latest after the final bit of the identification number and an additional bit.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 23, 2021
    Assignee: Robert Bosch GmbH
    Inventors: Arthur Mutter, Simon Weissenmayer, Steffen Walker
  • Patent number: 10925801
    Abstract: The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: February 23, 2021
    Assignees: SOMMETRICS, INC., TTP PLC.
    Inventors: Jerome K. Aarestad, Stephen Maine, Thomas John Harrison
  • Patent number: 10909678
    Abstract: A method and apparatus for monitoring a human or animal subject in a room using video imaging of the subject and analysis of the video image to derive an estimate of vital signs such as heart rate or breathing rate. The method includes determination of whether the subject in the images is still or moving, and whether any of the regions from which vital signs are being detected are not on the subject. The subject's movement may be manually or automatically detected, and the determination of whether regions from which vital signs are being detected are not on the subject can be input manually, by displaying the regions to the user in a visually distinguishable manner, or automatically. Vital signs measurements are only displayed if the subject is determined as being still and if there are no regions in the image which are returning vital signs signals but are not determined as being on the subject.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: February 2, 2021
    Assignee: OXEHEALTH LIMITED
    Inventors: Nicholas Dunkley Hutchinson, Oliver John Gibson, Peter Richard Dodds
  • Patent number: 10909168
    Abstract: Database systems and techniques are disclosed for accessing data stores of digital medical images, processing the digital images, and displaying the digital images to efficiently provide information in an interactive user interface. The disclosure may advantageously provide efficient and rapid dynamic interaction with digital images accessed from one or more databases to enable user detection of differences between related digital images. Interactive user interfaces may be dynamically updated to provide rapid comparison of digital images. Further, digital images from multiple data sources may be automatically sorted by the system according to attributes associated with the images and rules and/or preferences of the user. In an embodiment the user may select a digital image from a first data source, and the system automatically determines and displays one or more comparison images from other image data sources.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: February 2, 2021
    Assignee: MERGE HEALTHCARE SOLUTIONS INC.
    Inventors: Murray A. Reicher, Evan K. Fram
  • Patent number: 10881327
    Abstract: A device for recognizing activity of an object. The device has a housing configured to be attached to the object and a processing unit disposed in the housing has a processor and a movement sensor. The movement sensor measures a signal related to the movement of the object during a time window. The processor assigns at least one preliminary activity label to the time window based on at least one numerical descriptor computed from the signal. The processor then determines whether to perform additional analysis dependent upon at least the preliminary activity label. The processor then assigns a final activity label to the time window.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: January 5, 2021
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Eric C. Lobner, James W. Howard, Richard J. Moore, Jennifer F. Schumacher, Brian J. Stankiewicz
  • Patent number: 10842385
    Abstract: A vascular impedance measuring device may comprise a processing component capable of processing raw pressure and flow wave data and a pressure measuring component capable of providing pressure wave data from a specified point in a vessel and forwarding the pressure wave data to the processing component. The device may further include a flow measuring component capable of providing flow wave data from the specified point or a point near the specified point in the vessel and forwarding the flow wave data to the processing component. The processing component processes the raw pressure and flow wave data to produce an estimation of vascular impedance of the vessel from the specified point of measure and may provide data to a feedback system for therapy.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: November 24, 2020
    Assignee: Rush University Medical Center
    Inventor: Andrew Kelly Johnson
  • Patent number: 10832138
    Abstract: Methods and apparatus for extending a neural network, reducing its dimension and processing input data are provided. The method of extending a neural network involves selecting, with a processor, a node of a neural network, adding a new node in a layer that includes the selected node, and setting connection weights of the new node based on connection weights of the selected node.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: November 10, 2020
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Heeyoul Choi
  • Patent number: 10743777
    Abstract: Disclosed embodiments pertain to cardiovascular parameter (e.g. heart rate) measurements when motion is present. Biometric sensor signal measurements may be obtained based on cardiovascular parameters of a user; and motion sensor signal measurements may be obtained based on user motion. An activity type may be determined based on the motion sensor signals. For example, when non-motion related frequencies in a frequency domain representation of the biometric sensor signal are obscured by user motion, an activity type may be determined based on the motion sensor signals. Further, based on the activity type, for each cardiovascular parameter (e.g. heart rate), a corresponding likely cardiovascular parameter value (e.g. a likely heart rate) may be determined. A corresponding fundamental frequency associated with the biometric sensor signal may then be determined for each cardiovascular parameter based on the motion sensor signal measurements and the corresponding likely cardiovascular parameter value.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: August 18, 2020
    Assignee: QUALCOMM Incorporated
    Inventors: Russel Martin, Shashank Narayanan, Hithesh Reddivari, Vidyut Naware, Igor Tchertkov, Joseph Czompo
  • Patent number: 10722125
    Abstract: A system and method for blood pressure signal acquisition using a pressure sensor array. A solution is provided for a non-inflatable, non-invasive, continuous blood pressure waveform and blood pressure acquisition system. The system is operative to combine signals from various sensing elements where the less accurate sensor elements are calibrated utilizing the more accurate sensor elements. Blood pressure measurements are acquired using very sensitive pressure sensors that detect slight pressure changes through the skin, which are sampled and processed to yield a blood pressure signal, which is processed to yield actual systolic and diastolic continuous and or intermittent blood pressure readings. By sampling and detecting the signal in each of the sensors, the sensor that is best placed on the target artery is found and the signals from that sensor is used to weight the signals from other sensors based on signal quality.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: July 28, 2020
    Assignee: LIVEMETRIC (MEDICAL) S.A.
    Inventors: Nir Efraim Joseph Tal, Tomer Bentzion
  • Patent number: 10709341
    Abstract: Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: July 14, 2020
    Assignee: ST. JUDE MEDICAL LUXEMBOURG HOLDINGS II S.A.R.L.
    Inventors: Jason White, Ralph Jordan, John Erik Moore, Jay Yadav
  • Patent number: 10682063
    Abstract: A system and method for blood pressure signal acquisition using a pressure sensor array. A solution is provided for a non-inflatable, non-invasive, continuous blood pressure waveform and blood pressure acquisition system. The system is operative to combine signals from various sensing elements where the less accurate sensor elements are calibrated utilizing the more accurate sensor elements. Blood pressure measurements are acquired using very sensitive pressure sensors that detect slight pressure changes through the skin, which are sampled and processed to yield a blood pressure signal, which is processed to yield actual systolic and diastolic continuous and or intermittent blood pressure readings. By sampling and detecting the signal in each of the sensors, the sensor that is best placed on the target artery is found and the signals from that sensor is used to weight the signals from other sensors based on signal quality.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: June 16, 2020
    Assignee: LIVEMETRIC (MEDICAL) S.A.
    Inventors: Nir Efraim Joseph Tal, Tomer Bentzion
  • Patent number: 10663495
    Abstract: An averaging unit includes: a plurality of sensor connectors to which current sensors are detachably connected; an averager that generates an averaged signal for at least two detection voltage signals outputted from the current sensors connected to the sensor connectors; and an outputter that outputs the averaged signal.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: May 26, 2020
    Assignee: HIOKI DENKI KABUSHIKI KAISHA
    Inventors: Yoichiro Takeuchi, Hajime Yoda
  • Patent number: 10660788
    Abstract: There is provided a method for controlling a flow of fluid in the vas deferens in order to obtain a controlled male contraception. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow vas deferens, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the vas deferens. The method can be used for restricting or stopping the flow in the vas deferens, or for actively moving the fluid in the vas deferens, with a low risk of injuring the organ.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: May 26, 2020
    Inventor: Peter Forsell
  • Patent number: 10646646
    Abstract: Implantable infusion apparatus, systems and methods that involve the use of a sensor that is associated with the catheter outlet.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: May 12, 2020
    Assignee: The Alfred E. Mann Found. For Scientific Research
    Inventors: Lawrence Scott Ring, Peter C. Lord, Scott R. Gibson, Sam W. Bowman, Brian M. Shelton
  • Patent number: 10632240
    Abstract: A ventricular assist device incorporating a rotary pump configured to be in fluid communication with a heart and systemic circulation of a subject to assist blood flow from the heart to the systemic circulation. The device includes a pump drive circuit for applying power to the pump, one or more sensors for sensing one or more electrogram signals (such as subcutaneous pre-cordial electrode signals) in the patient, and a signal processing circuit to determine the presence or absence of a reduction in cardiac blood flow, ischemic condition or myocardial infarction condition based on subcutaneous pre-cordial electrode signals, to control power supplied to the pump from the pump drive circuit, and to operate the pump in either a normal sinus rhythm mode in the absence of an ischemic condition or myocardial infarction condition, or a modified mode of operation in the presence of an ischemic condition or myocardial infarction condition.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: April 28, 2020
    Assignee: HeartWare, Inc.
    Inventor: Barry M. Yomtov
  • Patent number: 10596307
    Abstract: A blood pump incorporating a rotary pump such as a rotary impeller pump implantable in fluid communication with a ventricle and an artery to assist blood flow from the ventricle to the artery. The device may include a pump drive circuit supplying power to the pump, one or more sensors for sensing one or more electrophysiological signals such as subcutaneous, pre-cordial ECG signals and a signal processing circuit connected to the sensors and to the pump drive circuit. The signal processing circuit is operative to detect the sensor signals and control power supplied to the pump from the pump drive circuit so that the pump may run in a normal sinus rhythm mode, with a varying speed synchronized with the cardiac cycle. When an ischemic or myocardial infarction condition is detected, the pump drive circuit may also run the pump in an ischemia or myocardial infarction mode different from the normal sinus rhythm mode.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: March 24, 2020
    Assignee: HeartWare, Inc.
    Inventor: Barry M. Yomtov
  • Patent number: 10566151
    Abstract: An item such as a fabric-based item may have one or more input devices. The input devices may have terminals that are electrically coupled to control circuitry. The control circuitry may make resistance measurements, capacitance measurements, and other measurements on the input devices to determine whether the input devices have been pressed by a user's finger or have otherwise received input. The input devices may be used to form an array of switches for a keyboard, may form buttons on an electronic device housing or case, may be part of an item of clothing, or may be incorporated into other items such as fabric-based items. The input devices may have collapsible fabric structures such as collapsible fabric domes. The terminals of the input devices may be formed from conductive strands of material in the fabric domes or may be supported by other structures that buckle under applied pressure.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: February 18, 2020
    Assignee: Apple Inc.
    Inventors: Paul Xiaopeng Wang, Siddhartha Hegde, Daniel D. Sunshine, Zheng Gao
  • Patent number: 10512427
    Abstract: A bladder fullness level of a patient may be determined based on a frequency of mechanical oscillations of the bladder of the patient. The bladder may mechanically oscillate in response to the occurrence of non-micturition contractions of the bladder of the patient, which are contractions not associated with urine release. The frequency at which the bladder oscillates, e.g., following a non-micturition contraction, may have a correlation to the bladder fullness level. In some examples, a medical device may be configured to control the delivery of electrical stimulation therapy to the patient based on the oscillation frequency of the bladder. In addition, or instead to controlling therapy based on the oscillation frequency of the bladder, a notification, such as a patient or patient caretaker notification, may be generated (e.g., automatically by a processor of a device) based on the oscillation frequency of the bladder.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: December 24, 2019
    Assignee: Medtronic, Inc.
    Inventors: Richard T. Stone, Keith A. Miesel
  • Patent number: 10506932
    Abstract: A vascular viscoelasticity evaluation device and method in which, a pulse wave obtained using a cuff is subjected to first derivation, a positive amplitude peak value Vf1 that occurs first and a negative amplitude peak value Vr2 that occurs second out of a plurality of negative amplitude peak values are detected in a state in which an external force substantially the same as or greater than the systolic blood pressure has been exerted on a blood vessel, and a ratio of the positive amplitude peak value Vf1 that occurs first to the negative amplitude peak value Vr2 that occurs second is calculated, and then the vascular viscoelasticity is evaluated on the basis of this calculated ratio.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: December 17, 2019
    Assignees: Shisei Datum Co., Ltd., RIKEN
    Inventors: Yukiyoshi Saito, Ryutaro Himeno, Shu Takagi, Fuyou Liang
  • Patent number: 10504286
    Abstract: Methods and apparatus for anonymizing neuromuscular signals used to generate a musculoskeletal representation. The method comprises recording, using a plurality of neuromuscular sensors arranged on one or more wearable devices, a plurality of neuromuscular signals from a user, providing as input to a trained statistical model, the plurality of neuromuscular signals and/or information based on the plurality of neuromuscular signals; and generating, the musculoskeletal representation based, at least in part, on an output of the trained statistical model, wherein the musculoskeletal representation is an anonymized musculoskeletal representation from which at least one personal characteristic of the user has been removed.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: December 10, 2019
    Assignee: CTRL-labs Corporation
    Inventors: Patrick Kaifosh, Tudor Giurgica-Tiron, Steven Kober, Adam Al-natsheh, Alexandre Barachant
  • Patent number: 10499827
    Abstract: A method and system are provided for measuring the cognitive state of an individual by combining analysis of 2 independent quantities derived from a single sensor. The method comprises placing an array of electrocardiogram (ECG) sensors in contact with the individual. The sensors continually measure the ECG voltages and signal-to-noise ratios from each ECG. A distance to sensor and pressure applied to sensor our calculated for each ECG sensor that corresponds to the ECG voltage and signal-to-noise ratio measurements from each respective ECG sensor. Next, a graphical distance and pressure map is generated based on the combined signal-to-noise ratios of the ECG sensors and continually analyzed to determine the cognitive state of the individual.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: December 10, 2019
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zdenek Moravek, David Kunes, Lukas Maly
  • Patent number: 10492473
    Abstract: A system for monitoring vital signs of a pet animal comprises an annular band, an accelerometer configured to measure at least one of resting patterns, activity patterns, movement patterns, position patterns relating to, for example the pet animal relieving itself, lameness and scratching, and a non-accelerometer sensor configured to measure at least one of the following non-accelerometer-measured bioparameters of the pet animal: temperature, pulse rate, respiration rate. One or more processors are configured to receive sensor output data and reference data concerning the measured bioparameters of the pet animal or of a population of the pet animal, and determine a suspicion of a specific medical condition by: (i) scoring at least two bioparameters and comparing a cumulative score to a threshold cumulative score or to a threshold cumulative range; or (ii) identifying an abnormal pattern. The processor(s) may send an alert if at least one specific medical condition is suspected.
    Type: Grant
    Filed: April 9, 2017
    Date of Patent: December 3, 2019
    Assignee: PETPACE LTD.
    Inventors: Avi Menkes, Asaf Dagan
  • Patent number: 10398327
    Abstract: A method is provided for non-contact cardiac assessment of a subject. Images of the subject are captured from at least two synchronized independent imaging devices spaced equidistant from the subject and positioned such that each imaging device captures an image of the subject different from other imaging devices. Spectral components of the captured images are extracted. The extracted spectral components are analyzed. A signal corresponding to cardiac information is identified in the extracted spectral components. The identified signal corresponding to the cardiac information is extracted from the extracted spectral components.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 3, 2019
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Justin R. Estepp, Ethan B. Blackford, Christopher M. Meier
  • Patent number: 10390761
    Abstract: Provided is a device which can utilize a motion sensor installed in a mobile device. A smartphone includes a motion sensor and a controller. The motion sensor detects a motion factor. The controller processes the motion factor detected by the motion sensor as a self-control factor. The controller can process the motion factor detected by the motion sensor as a vital-sign factor of a user.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: August 27, 2019
    Assignee: KYOCERA Corporation
    Inventor: Hiromi Ajima
  • Patent number: 10368808
    Abstract: Embodiments describe a method of determining etiology of undiagnosed events comprising monitoring electrocardiogram signals and blood pressure of a patient via a medical device, capturing one or more of an ECG segment and a BP reading in response to a triggering event, classifying one or more of the ECG segment and BP reading as normal or abnormal, and determining etiology of undiagnosed symptomatic events based on the classification. Embodiments further describe a medical device comprising sensors for monitoring ECG signals and BP of a patient, circuitry for capturing one or more of ECG segments and BP readings of a patient in response to a triggering event, and a processor for communicating one of more of captured ECG segments and captured BP readings to a remote monitoring center directly or indirectly where the captured ECG segments and captured BP readings are classified as normal or abnormal.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 6, 2019
    Assignee: Medtronic Monitoring, Inc.
    Inventors: Brian B. Lee, ShaileshKumar V. Musley, Robert W. Stadler, Maneesh Shrivastav, Randal Schulhauser, Stacie Vilendrer
  • Patent number: 10368753
    Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 6, 2019
    Assignee: The Johns Hopkins University
    Inventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A. C. Lima, Chia-Ying Liu, Boaz D. Rosen