Cardiovascular Patents (Class 600/481)
  • Patent number: 11109829
    Abstract: A medical image diagnostic apparatus according to an embodiment includes an estimation unit, an extraction unit, and a specifying unit. The estimation unit estimates a position of a plaque in a blood vessel based on data of CT images constituting a time series, with the blood vessel being enhanced by a contrast medium. The extraction unit extracts regions constituting the blood vessel from the CT images. The specifying unit specifies stress values respectively corresponding to the regions based on a moving displacement due to cardiac pulsation in each of the regions, and specifies an exfoliation risk of the plaque based on an index indicating hardness of the plaque and the stress value in the region corresponding to the position of the plaque.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: September 7, 2021
    Assignee: Canon Medical Systems Corporation
    Inventors: Hideaki Ishii, Satoshi Wakai, Kazumasa Arakita, Takuma Igarashi, Yasuko Fujisawa, Shigeo Kaminaga, Kenji Hirohata, Junichiro Ooga
  • Patent number: 11109973
    Abstract: Steady flow hydrodynamic performance testing is performed on a valved prosthesis mounted in a test conduit. The system is configured with prescribed test condition inputs into control software. Upon test initiation, a steady flow pump is activated and automatically adjusts its flow based on the software logic to meet the prescribed first test condition. During forward flow pressure drop testing, the flow pump is automatically adjusted to achieve and hold a particular flow rate. During back flow leakage testing, the steady flow pump is automatically adjusted to achieve and hold a particular differential pressure across the test prosthesis while a flow rate of the leakage flow is measured. After a first test condition has been achieved, the system control software then automatically adjusts the pump flow rate to meet a second test condition. This process then continues until all conditions set by software inputs are evaluated.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: September 7, 2021
    Assignee: Biomedical Device Consultants and Laboratories of Colorado, LLC
    Inventors: Benjamin McCloskey, Craig Weinberg
  • Patent number: 11089978
    Abstract: A detection apparatus and a method are provided for detecting a respiratory movement of a patient. The detection apparatus includes at least two metallic U-shaped signal coupling elements that are interleaved so that between the signal coupling elements arises at least one coupling point at which a signal may be transferred between the two signal coupling elements. Analysis electronics are configured to detect a change in a received signal produced in a second of the signal coupling elements that is acting as a receiver in the near-field region of the first signal coupling elements as a result of a signal given for one of the signal coupling elements that is acting as a transmitter being coupled into the second of the signal coupling elements, which change indicates the respiratory movement.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: August 17, 2021
    Assignee: Siemens Healthcare GmbH
    Inventor: Sebastian Martius
  • Patent number: 11069064
    Abstract: A method and a system for modelling a human heart based on a plurality of emission tomography images representing concentrations of a tracer that has been injected at a specific time is presented. The method comprising: extracting time activity curves of a tracer that has been injected for a plurality of pixels and/or voxels; identifying first-pass peaks of the time activity curves corresponding to an arrival time of the injected tracer at the corresponding pixel/voxel; defining a model comprising at least two portions of the heart; and arranging the at least two portions in relation to each other by comparing the arrival times of the first-pass peaks. The method and model may be used to obtain an estimate of the volume of the left or right atrium of the human heart.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: July 20, 2021
    Assignee: MEDTRACE PHARMA A/S
    Inventors: Jens Sørensen, Hendrik Johannes Harms
  • Patent number: 11056233
    Abstract: A controller-based apparatus for diagnosis and treatment of a subject with acquired brain injury and dysfunction. Various embodiments of the invention described herein recognize that different body postures affect the autonomic nervous system differently, and therefore various external stimuli may have different therapeutic efficacies when a patient or subject is in each body posture. Postures, such as walking, sitting, standing, prone and supine, have different effects on the autonomic nervous system, and therefore some stimuli have different physiological efficacies while a patient or subject is in a given body posture. Disclosed embodiments of the present invention leverage this relationship to provide a controller-based apparatus that determines a combination of posture and stimulus that has optimal therapeutic effect, while minimizing health practitioner involvement.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: July 6, 2021
    Inventor: Victor M. Pedro
  • Patent number: 11000189
    Abstract: Computer implemented methods, systems and devices are provided to monitor for potential heart failure (HF). Cardiac activity (CA) data is obtained and filtered to obtain respiration data indicative of a respiration pattern. The respiration data is analyzed to determine one or more respiration characteristics of interest (COI) that are recorded along with collection time information to form an HF monitoring log. Additionally or alternatively, the CA data is analyzed to detect an event of interest. The cardiac activity data is filtered to obtain respiration data indicative of a respiration pattern, and the respiration data is analyzed for respiration induced under detection of the event of interest from the CA data.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: May 11, 2021
    Assignee: PACESETTER, INC.
    Inventors: Stephanie C. Sun, Xiaoyi Min, Alan B. Vogel, Fujian Qu, Stuart Rosenberg
  • Patent number: 10980430
    Abstract: In one embodiment of the invention, a cuff-less blood pressure measuring system is disclosed including cuff-less blood pressure scanner with a vital signs signal processor having an adaptive blood pressure model. A machine learning process is further disclosed to tune the adaptive blood pressure model of the cuff-less blood pressure measuring system to the user.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: April 20, 2021
    Assignee: HEALTHY.IO LTD.
    Inventors: Piotr Przybyszewski, Eunseog Youn, Walter De Brouwer, Brian G. La Plume, Babak Aghazadeh, Maxim Akhterov
  • Patent number: 10966617
    Abstract: Techniques exist for measuring local blood velocity of flow rate waveforms in, for example, mammalian vascular segments. A method and system for deriving information on disease in vascular segments, for example mean pressure, drop in mean pressure and/or hydraulic resistance, from such measured waveforms is described. The waveforms can, for example, be measured non-invasively using Doppler ultrasound or magnetic resonance techniques. Form factors (Vff, Pff) for the velocity waveform and the central arterial pressure are determined. Stenosis may be detected by detecting changes e.g in Vff/Pff.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: April 6, 2021
    Assignee: Bluedop Medical Ltd.
    Inventors: David H. King, Mohammed Al-Qaisi
  • Patent number: 10925801
    Abstract: The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: February 23, 2021
    Assignees: SOMMETRICS, INC., TTP PLC.
    Inventors: Jerome K. Aarestad, Stephen Maine, Thomas John Harrison
  • Patent number: 10929334
    Abstract: A subscriber station for a serial bus system are provided. The subscriber station includes a message creating device for creating a message to be transmitted serially via a bus of the bus system for at least one further subscriber station of the bus system, so that the message has a first time segment and a second time segment, and a transceiver device for serially sending the message to the bus in such a way that data in the first time segment are sent with a slower data rate than in the second time segment, the transceiver device having in the second time segment at least at times an exclusive, collision-free access to the bus, the message creating device to insert an identification number into the first time segment and to begin the second time segment at the latest after the final bit of the identification number and an additional bit.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 23, 2021
    Assignee: Robert Bosch GmbH
    Inventors: Arthur Mutter, Simon Weissenmayer, Steffen Walker
  • Patent number: 10909678
    Abstract: A method and apparatus for monitoring a human or animal subject in a room using video imaging of the subject and analysis of the video image to derive an estimate of vital signs such as heart rate or breathing rate. The method includes determination of whether the subject in the images is still or moving, and whether any of the regions from which vital signs are being detected are not on the subject. The subject's movement may be manually or automatically detected, and the determination of whether regions from which vital signs are being detected are not on the subject can be input manually, by displaying the regions to the user in a visually distinguishable manner, or automatically. Vital signs measurements are only displayed if the subject is determined as being still and if there are no regions in the image which are returning vital signs signals but are not determined as being on the subject.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: February 2, 2021
    Assignee: OXEHEALTH LIMITED
    Inventors: Nicholas Dunkley Hutchinson, Oliver John Gibson, Peter Richard Dodds
  • Patent number: 10909168
    Abstract: Database systems and techniques are disclosed for accessing data stores of digital medical images, processing the digital images, and displaying the digital images to efficiently provide information in an interactive user interface. The disclosure may advantageously provide efficient and rapid dynamic interaction with digital images accessed from one or more databases to enable user detection of differences between related digital images. Interactive user interfaces may be dynamically updated to provide rapid comparison of digital images. Further, digital images from multiple data sources may be automatically sorted by the system according to attributes associated with the images and rules and/or preferences of the user. In an embodiment the user may select a digital image from a first data source, and the system automatically determines and displays one or more comparison images from other image data sources.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: February 2, 2021
    Assignee: MERGE HEALTHCARE SOLUTIONS INC.
    Inventors: Murray A. Reicher, Evan K. Fram
  • Patent number: 10881327
    Abstract: A device for recognizing activity of an object. The device has a housing configured to be attached to the object and a processing unit disposed in the housing has a processor and a movement sensor. The movement sensor measures a signal related to the movement of the object during a time window. The processor assigns at least one preliminary activity label to the time window based on at least one numerical descriptor computed from the signal. The processor then determines whether to perform additional analysis dependent upon at least the preliminary activity label. The processor then assigns a final activity label to the time window.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: January 5, 2021
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Eric C. Lobner, James W. Howard, Richard J. Moore, Jennifer F. Schumacher, Brian J. Stankiewicz
  • Patent number: 10842385
    Abstract: A vascular impedance measuring device may comprise a processing component capable of processing raw pressure and flow wave data and a pressure measuring component capable of providing pressure wave data from a specified point in a vessel and forwarding the pressure wave data to the processing component. The device may further include a flow measuring component capable of providing flow wave data from the specified point or a point near the specified point in the vessel and forwarding the flow wave data to the processing component. The processing component processes the raw pressure and flow wave data to produce an estimation of vascular impedance of the vessel from the specified point of measure and may provide data to a feedback system for therapy.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: November 24, 2020
    Assignee: Rush University Medical Center
    Inventor: Andrew Kelly Johnson
  • Patent number: 10832138
    Abstract: Methods and apparatus for extending a neural network, reducing its dimension and processing input data are provided. The method of extending a neural network involves selecting, with a processor, a node of a neural network, adding a new node in a layer that includes the selected node, and setting connection weights of the new node based on connection weights of the selected node.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: November 10, 2020
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Heeyoul Choi
  • Patent number: 10743777
    Abstract: Disclosed embodiments pertain to cardiovascular parameter (e.g. heart rate) measurements when motion is present. Biometric sensor signal measurements may be obtained based on cardiovascular parameters of a user; and motion sensor signal measurements may be obtained based on user motion. An activity type may be determined based on the motion sensor signals. For example, when non-motion related frequencies in a frequency domain representation of the biometric sensor signal are obscured by user motion, an activity type may be determined based on the motion sensor signals. Further, based on the activity type, for each cardiovascular parameter (e.g. heart rate), a corresponding likely cardiovascular parameter value (e.g. a likely heart rate) may be determined. A corresponding fundamental frequency associated with the biometric sensor signal may then be determined for each cardiovascular parameter based on the motion sensor signal measurements and the corresponding likely cardiovascular parameter value.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: August 18, 2020
    Assignee: QUALCOMM Incorporated
    Inventors: Russel Martin, Shashank Narayanan, Hithesh Reddivari, Vidyut Naware, Igor Tchertkov, Joseph Czompo
  • Patent number: 10722125
    Abstract: A system and method for blood pressure signal acquisition using a pressure sensor array. A solution is provided for a non-inflatable, non-invasive, continuous blood pressure waveform and blood pressure acquisition system. The system is operative to combine signals from various sensing elements where the less accurate sensor elements are calibrated utilizing the more accurate sensor elements. Blood pressure measurements are acquired using very sensitive pressure sensors that detect slight pressure changes through the skin, which are sampled and processed to yield a blood pressure signal, which is processed to yield actual systolic and diastolic continuous and or intermittent blood pressure readings. By sampling and detecting the signal in each of the sensors, the sensor that is best placed on the target artery is found and the signals from that sensor is used to weight the signals from other sensors based on signal quality.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: July 28, 2020
    Assignee: LIVEMETRIC (MEDICAL) S.A.
    Inventors: Nir Efraim Joseph Tal, Tomer Bentzion
  • Patent number: 10709341
    Abstract: Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: July 14, 2020
    Assignee: ST. JUDE MEDICAL LUXEMBOURG HOLDINGS II S.A.R.L.
    Inventors: Jason White, Ralph Jordan, John Erik Moore, Jay Yadav
  • Patent number: 10682063
    Abstract: A system and method for blood pressure signal acquisition using a pressure sensor array. A solution is provided for a non-inflatable, non-invasive, continuous blood pressure waveform and blood pressure acquisition system. The system is operative to combine signals from various sensing elements where the less accurate sensor elements are calibrated utilizing the more accurate sensor elements. Blood pressure measurements are acquired using very sensitive pressure sensors that detect slight pressure changes through the skin, which are sampled and processed to yield a blood pressure signal, which is processed to yield actual systolic and diastolic continuous and or intermittent blood pressure readings. By sampling and detecting the signal in each of the sensors, the sensor that is best placed on the target artery is found and the signals from that sensor is used to weight the signals from other sensors based on signal quality.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: June 16, 2020
    Assignee: LIVEMETRIC (MEDICAL) S.A.
    Inventors: Nir Efraim Joseph Tal, Tomer Bentzion
  • Patent number: 10660788
    Abstract: There is provided a method for controlling a flow of fluid in the vas deferens in order to obtain a controlled male contraception. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow vas deferens, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the vas deferens. The method can be used for restricting or stopping the flow in the vas deferens, or for actively moving the fluid in the vas deferens, with a low risk of injuring the organ.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: May 26, 2020
    Inventor: Peter Forsell
  • Patent number: 10663495
    Abstract: An averaging unit includes: a plurality of sensor connectors to which current sensors are detachably connected; an averager that generates an averaged signal for at least two detection voltage signals outputted from the current sensors connected to the sensor connectors; and an outputter that outputs the averaged signal.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: May 26, 2020
    Assignee: HIOKI DENKI KABUSHIKI KAISHA
    Inventors: Yoichiro Takeuchi, Hajime Yoda
  • Patent number: 10646646
    Abstract: Implantable infusion apparatus, systems and methods that involve the use of a sensor that is associated with the catheter outlet.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: May 12, 2020
    Assignee: The Alfred E. Mann Found. For Scientific Research
    Inventors: Lawrence Scott Ring, Peter C. Lord, Scott R. Gibson, Sam W. Bowman, Brian M. Shelton
  • Patent number: 10632240
    Abstract: A ventricular assist device incorporating a rotary pump configured to be in fluid communication with a heart and systemic circulation of a subject to assist blood flow from the heart to the systemic circulation. The device includes a pump drive circuit for applying power to the pump, one or more sensors for sensing one or more electrogram signals (such as subcutaneous pre-cordial electrode signals) in the patient, and a signal processing circuit to determine the presence or absence of a reduction in cardiac blood flow, ischemic condition or myocardial infarction condition based on subcutaneous pre-cordial electrode signals, to control power supplied to the pump from the pump drive circuit, and to operate the pump in either a normal sinus rhythm mode in the absence of an ischemic condition or myocardial infarction condition, or a modified mode of operation in the presence of an ischemic condition or myocardial infarction condition.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: April 28, 2020
    Assignee: HeartWare, Inc.
    Inventor: Barry M. Yomtov
  • Patent number: 10596307
    Abstract: A blood pump incorporating a rotary pump such as a rotary impeller pump implantable in fluid communication with a ventricle and an artery to assist blood flow from the ventricle to the artery. The device may include a pump drive circuit supplying power to the pump, one or more sensors for sensing one or more electrophysiological signals such as subcutaneous, pre-cordial ECG signals and a signal processing circuit connected to the sensors and to the pump drive circuit. The signal processing circuit is operative to detect the sensor signals and control power supplied to the pump from the pump drive circuit so that the pump may run in a normal sinus rhythm mode, with a varying speed synchronized with the cardiac cycle. When an ischemic or myocardial infarction condition is detected, the pump drive circuit may also run the pump in an ischemia or myocardial infarction mode different from the normal sinus rhythm mode.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: March 24, 2020
    Assignee: HeartWare, Inc.
    Inventor: Barry M. Yomtov
  • Patent number: 10566151
    Abstract: An item such as a fabric-based item may have one or more input devices. The input devices may have terminals that are electrically coupled to control circuitry. The control circuitry may make resistance measurements, capacitance measurements, and other measurements on the input devices to determine whether the input devices have been pressed by a user's finger or have otherwise received input. The input devices may be used to form an array of switches for a keyboard, may form buttons on an electronic device housing or case, may be part of an item of clothing, or may be incorporated into other items such as fabric-based items. The input devices may have collapsible fabric structures such as collapsible fabric domes. The terminals of the input devices may be formed from conductive strands of material in the fabric domes or may be supported by other structures that buckle under applied pressure.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: February 18, 2020
    Assignee: Apple Inc.
    Inventors: Paul Xiaopeng Wang, Siddhartha Hegde, Daniel D. Sunshine, Zheng Gao
  • Patent number: 10512427
    Abstract: A bladder fullness level of a patient may be determined based on a frequency of mechanical oscillations of the bladder of the patient. The bladder may mechanically oscillate in response to the occurrence of non-micturition contractions of the bladder of the patient, which are contractions not associated with urine release. The frequency at which the bladder oscillates, e.g., following a non-micturition contraction, may have a correlation to the bladder fullness level. In some examples, a medical device may be configured to control the delivery of electrical stimulation therapy to the patient based on the oscillation frequency of the bladder. In addition, or instead to controlling therapy based on the oscillation frequency of the bladder, a notification, such as a patient or patient caretaker notification, may be generated (e.g., automatically by a processor of a device) based on the oscillation frequency of the bladder.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: December 24, 2019
    Assignee: Medtronic, Inc.
    Inventors: Richard T. Stone, Keith A. Miesel
  • Patent number: 10506932
    Abstract: A vascular viscoelasticity evaluation device and method in which, a pulse wave obtained using a cuff is subjected to first derivation, a positive amplitude peak value Vf1 that occurs first and a negative amplitude peak value Vr2 that occurs second out of a plurality of negative amplitude peak values are detected in a state in which an external force substantially the same as or greater than the systolic blood pressure has been exerted on a blood vessel, and a ratio of the positive amplitude peak value Vf1 that occurs first to the negative amplitude peak value Vr2 that occurs second is calculated, and then the vascular viscoelasticity is evaluated on the basis of this calculated ratio.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: December 17, 2019
    Assignees: Shisei Datum Co., Ltd., RIKEN
    Inventors: Yukiyoshi Saito, Ryutaro Himeno, Shu Takagi, Fuyou Liang
  • Patent number: 10499827
    Abstract: A method and system are provided for measuring the cognitive state of an individual by combining analysis of 2 independent quantities derived from a single sensor. The method comprises placing an array of electrocardiogram (ECG) sensors in contact with the individual. The sensors continually measure the ECG voltages and signal-to-noise ratios from each ECG. A distance to sensor and pressure applied to sensor our calculated for each ECG sensor that corresponds to the ECG voltage and signal-to-noise ratio measurements from each respective ECG sensor. Next, a graphical distance and pressure map is generated based on the combined signal-to-noise ratios of the ECG sensors and continually analyzed to determine the cognitive state of the individual.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: December 10, 2019
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zdenek Moravek, David Kunes, Lukas Maly
  • Patent number: 10504286
    Abstract: Methods and apparatus for anonymizing neuromuscular signals used to generate a musculoskeletal representation. The method comprises recording, using a plurality of neuromuscular sensors arranged on one or more wearable devices, a plurality of neuromuscular signals from a user, providing as input to a trained statistical model, the plurality of neuromuscular signals and/or information based on the plurality of neuromuscular signals; and generating, the musculoskeletal representation based, at least in part, on an output of the trained statistical model, wherein the musculoskeletal representation is an anonymized musculoskeletal representation from which at least one personal characteristic of the user has been removed.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: December 10, 2019
    Assignee: CTRL-labs Corporation
    Inventors: Patrick Kaifosh, Tudor Giurgica-Tiron, Steven Kober, Adam Al-natsheh, Alexandre Barachant
  • Patent number: 10492473
    Abstract: A system for monitoring vital signs of a pet animal comprises an annular band, an accelerometer configured to measure at least one of resting patterns, activity patterns, movement patterns, position patterns relating to, for example the pet animal relieving itself, lameness and scratching, and a non-accelerometer sensor configured to measure at least one of the following non-accelerometer-measured bioparameters of the pet animal: temperature, pulse rate, respiration rate. One or more processors are configured to receive sensor output data and reference data concerning the measured bioparameters of the pet animal or of a population of the pet animal, and determine a suspicion of a specific medical condition by: (i) scoring at least two bioparameters and comparing a cumulative score to a threshold cumulative score or to a threshold cumulative range; or (ii) identifying an abnormal pattern. The processor(s) may send an alert if at least one specific medical condition is suspected.
    Type: Grant
    Filed: April 9, 2017
    Date of Patent: December 3, 2019
    Assignee: PETPACE LTD.
    Inventors: Avi Menkes, Asaf Dagan
  • Patent number: 10398327
    Abstract: A method is provided for non-contact cardiac assessment of a subject. Images of the subject are captured from at least two synchronized independent imaging devices spaced equidistant from the subject and positioned such that each imaging device captures an image of the subject different from other imaging devices. Spectral components of the captured images are extracted. The extracted spectral components are analyzed. A signal corresponding to cardiac information is identified in the extracted spectral components. The identified signal corresponding to the cardiac information is extracted from the extracted spectral components.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 3, 2019
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Justin R. Estepp, Ethan B. Blackford, Christopher M. Meier
  • Patent number: 10390761
    Abstract: Provided is a device which can utilize a motion sensor installed in a mobile device. A smartphone includes a motion sensor and a controller. The motion sensor detects a motion factor. The controller processes the motion factor detected by the motion sensor as a self-control factor. The controller can process the motion factor detected by the motion sensor as a vital-sign factor of a user.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: August 27, 2019
    Assignee: KYOCERA Corporation
    Inventor: Hiromi Ajima
  • Patent number: 10368808
    Abstract: Embodiments describe a method of determining etiology of undiagnosed events comprising monitoring electrocardiogram signals and blood pressure of a patient via a medical device, capturing one or more of an ECG segment and a BP reading in response to a triggering event, classifying one or more of the ECG segment and BP reading as normal or abnormal, and determining etiology of undiagnosed symptomatic events based on the classification. Embodiments further describe a medical device comprising sensors for monitoring ECG signals and BP of a patient, circuitry for capturing one or more of ECG segments and BP readings of a patient in response to a triggering event, and a processor for communicating one of more of captured ECG segments and captured BP readings to a remote monitoring center directly or indirectly where the captured ECG segments and captured BP readings are classified as normal or abnormal.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 6, 2019
    Assignee: Medtronic Monitoring, Inc.
    Inventors: Brian B. Lee, ShaileshKumar V. Musley, Robert W. Stadler, Maneesh Shrivastav, Randal Schulhauser, Stacie Vilendrer
  • Patent number: 10368753
    Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 6, 2019
    Assignee: The Johns Hopkins University
    Inventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A. C. Lima, Chia-Ying Liu, Boaz D. Rosen
  • Patent number: 10335081
    Abstract: An improved apparatus and method for interfacing a time variant waveform between two hardware environments. In one aspect, the invention comprises a circuit for accurately simulating the output of one or more types of sensing device (e.g., passive bridge pressure transducer) for use with a plurality of different monitoring and/or analysis devices, thereby obviating the need for specialized interface circuitry adapted to each different monitor/analyzer. In one exemplary embodiment, the sensing device comprises a non-invasive blood pressure monitor (NIBPM), which universally interfaces with prior art patient monitors via the interface circuit of the invention. In a second aspect of the invention, an improved NIBPM device incorporating the interface circuit is disclosed. An improved disconnect circuit adapted to sense the status of the electrical connection between the sensing device and monitor is also described.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: July 2, 2019
    Assignee: United States GTM Medical Devices
    Inventor: Ronald S. Conero
  • Patent number: 10335080
    Abstract: A wearable sensor apparatus comprises a motion sensor configured to sense two or three dimensional movement and orientation of the sensor and a vibration sensor configured to sense acoustic vibrations. The apparatus includes means for attaching the motion sensor and the vibration sensor to a body. The sensor apparatus enables long term monitoring of mechanomyographic muscle activity in combination with body motion for a number of applications.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: July 2, 2019
    Assignee: Imperial Innovations Limited
    Inventors: Ravi Vaidyanathan, Niamh Nowlan, Richard Woodward, Sandra Shefelbine
  • Patent number: 10307131
    Abstract: Systems and methods are disclosed for assessing the severity of plaque and/or stenotic lesions using contrast distribution predictions and measurements.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: June 4, 2019
    Assignee: HeartFlow, Inc.
    Inventors: Charles A. Taylor, Leo Grady, Sethuraman Sankaran, Souma Sengupta, Hyun Jin Kim, Nan Xiao
  • Patent number: 10299690
    Abstract: An electronic device for measuring biometric information is provided. The electronic device includes a sensor unit configured to detect an attitude of the electronic device, a biometric information measurement unit configured to detect biometric information on an examinee through a plurality of electrodes formed on at least one surface of the electronic device, a switch unit including a plurality of switches electrically connected to the plurality of electrodes and a controller configured to recognize an array of the plurality of electrodes based on the detected attitude of the electronic device and control the switch unit such that the recognized electrode array corresponds to a preset electrode array.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: May 28, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Ah-Young Choi, Young-Hyun Kim, Seong-Wook Jo, Jin-Hong Min
  • Patent number: 10271739
    Abstract: This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: April 30, 2019
    Assignee: Respiratory Motion, Inc.
    Inventors: Jenny E Freeman, Michael Lalli, Alex Mattfolk, Alexander Panasyuk, Charles Jahnke, Nathaniel Steiger, Svetlana V Panasyuk, Arvil Nagpal, James F Toy, IV, Roman Bokhenik, Anita Karcz
  • Patent number: 10271824
    Abstract: The various embodiments herein provide a device for analyzing a rectum gas discharge. The device comprises a central bag, a peripheral bag, and an electronic unit. The central bag comprises a gas inlet and a gas outlet on directionally opposite ends of a central bag surface. The peripheral bag is housed in a container and radially encapsulates the central bag. The electronic unit comprises a pressure sensor and a connector for further connecting a monitoring unit. The pressure sensor is attached over a surface of the peripheral bag. The central bag is attached to an anal canal of a patient and expands on ingestion of discharged rectal gas from the anal canal. The peripheral bag expands with the central bag resulting in activation of the pressure sensor to measure a gas collected in the central bag.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 30, 2019
    Inventor: Nooshin Jalili
  • Patent number: 10271751
    Abstract: A method for monitoring the blood pressure of a patient, comprising the following steps: determining a pulse arrival time signal from the patient 2 based on the pulse wave velocity method; determining an accelerometer signal from the patient 2; and triggering an additional measure or deriving a blood pressure value, taking into account the pulse arrival time signal and a DC component of the accelerometer signal. In this way, a possibility for monitoring the blood pressure of a patient is provided with which false alarms and/or unnecessary additional cuff-based blood pressure measurements can be avoided.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: April 30, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jens Muhlsteff, Geert Guy Georges Morren, Xavier Louis Marie Antoine Aubert
  • Patent number: 10213159
    Abstract: The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: February 26, 2019
    Assignee: SOTERA WIRELESS, INC.
    Inventors: Jim Moon, Gunnar Trommer, Caroline DiBattista
  • Patent number: 10206587
    Abstract: An image processing apparatus according to an embodiment includes a processing circuitry. The processing circuitry is configured to obtain images in a time series including images of a blood vessel of a subject and correlation information indicating a correlational relationship between physical indices of the blood vessel and function indices of the blood vessel related to vascular hemodynamics, calculate blood vessel morphology indices in a time series indicating morphology of the blood vessel of the subject, on a basis of the images in the time series, and identify a function index of the blood vessel of the subject, by using a physical index of the blood vessel of the subject obtained from the blood vessel morphology indices, on a basis of the correlation information.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: February 19, 2019
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Akira Kano, Kenji Hirohata, Junichiro Ooga, Mitsuaki Kato, Takuya Hongo, Akihiro Goryu, Shigeo Kaminaga, Yasuko Fujisawa, Satoshi Wakai, Yoshihiro Ikeda, Kazumasa Arakita
  • Patent number: 10206626
    Abstract: A biosignal measurement and transmission apparatus having a simplified signal slot as provided is configurable for receiving signals from a biosignal detection apparatus and a biosignal detection correction unit and for performing signal transfer and analysis operations.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: February 19, 2019
    Inventor: Chuen Wei Lu
  • Patent number: 10201285
    Abstract: A cuff of a blood pressure measurement device compresses a measurement site by being wrapped therearound. A control unit evaluates the wrapping strength of the cuff, by comparing a detection amount detected based on the output of a sensor with a history of the detection amount stored in the storage unit.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: February 12, 2019
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Yukiya Sawanoi, Shingo Yamashita, Toshiaki Yuasa
  • Patent number: 10136813
    Abstract: An information display and control system that enables a fast and easy understanding and management of the status of the patient's cardiovascular and ventilation systems is disclosed. The system can control administration and management of a patient's medication and fluids. The display is organized by goals related to management of patient's cardiovascular system, ventilation system, and medications and fluids administration and management. Such goals include hemodynamics, oxygenation, CO2 removal, medication status, and fluids status.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: November 27, 2018
    Inventor: Yasser A. Sowb
  • Patent number: 10130624
    Abstract: A stable pharmaceutical composition consisting of (a) benazepril, in free or pharmaceutically acceptable salt form; and (b) amlodipine, in free or pharmaceutically acceptable salt form. The composition is free of alkali and alkaline earth metal carbonates and phosphates. The composition is also free of excipients which increase the pH of microenvironment above 5. It is therefore not required to physically separate the two drugs from each other.
    Type: Grant
    Filed: January 25, 2006
    Date of Patent: November 20, 2018
    Assignee: LUPIN LIMITED
    Inventors: Veena Vithalapuram, Vijaya Kumar Thommandru, Himadri Sen
  • Patent number: 10098555
    Abstract: A biological information measurement apparatus capable of improving the SN ratio of a photoplethysmographic signal by reducing stray light in detection light that reaches a light-receiving unit from a light-emitting unit is provided. A biological information measurement apparatus includes a light-emitting unit that irradiates a finger, a light-receiving unit that receives and photoelectrically converts light transmitted through or reflected by the finger and outputs a photoplethysmographic signal, and a processing unit that obtains biological information on the basis of the photoplethysmographic signal. The light-emitting and light-receiving units are disposed, in plan view in a plane perpendicular to the direction of the emitted light or the received light, such that a line passing through the centers of the light-emitting unit and the light-receiving unit is slanted relative to a lengthwise direction of the finger.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: October 16, 2018
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Kazuhiro Yamaji, Hirofumi Tsuchimoto
  • Patent number: 10070839
    Abstract: The invention provides, in some aspects, a system for implementing a rule derived basis to display volumetric image sets. In various embodiments of the invention, the selection of the images to be displayed, the generation of the 3-D volumetric image from measured 2-D images including the rendering parameters and styles, the choice of viewing directions and 2-D projection images based on the viewing directions, the layout of the projection images, and the formation of a video can be determined using a rule derived basis. In an embodiment of the present invention, the user is presented with sequential images making up a video displayed based on their preferences without having to first manually adjust parameters. The present invention allows for novel ways of viewing such images to detect microcalcifications and obstructions when reviewing Digital Breast Tomosynthesis and other volumetric mammography images.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: September 11, 2018
    Assignee: PME IP PTY LTD
    Inventors: Malte Westerhoff, Detlev Stalling
  • Patent number: 10064560
    Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data sequence representing normal blood pressure of a patient, a second digital data sequence representing random blood pressure of a normal patient and a third digital data sequence representing a potentially abnormal blood pressure of a patient. A complexity processor calculates first, second and third complexity indices for the corresponding first, second and third digital data sequences respectively. A correlation processor uses the calculated first, second and third complexity indices to calculate one or more measures indicating deviation of the potentially abnormal blood pressure of the patient from a normal value.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: September 4, 2018
    Assignee: Siemens Healthcare GmbH
    Inventor: Hongxuan Zhang